COX10

General Information

Gene Name       : COX10
Gene ID             : ENSG00000006695.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: COX10)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COX10ENSG00000006695.1013.0819.9316.50ENCSR000AEF
HepG2COX10ENSG00000006695.109.2113.2211.21ENCSR985KAT
K562COX10ENSG00000006695.1017.6717.7417.70ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COX10 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COX10 RNA is bound by 3 proteins.  







eCLIP assay for COX10 is not avaliable on ENCORE database.





3 proteins are bound to COX10 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr171411184514111889+3'-UTR4.268484.20872K562IGF2BP1
chr171411083614110904+3'-UTR3.858963.19026HepG2HNRNPL
chr171402187814021968+intron-Distal3.854393.84494HepG2QKI
chr171399624013996309+intron-Distal3.822323.16986HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COX10 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COX10 is not available on ENCORE database.

  • 47 RBPs can affect the levels of COX10.  








The Knockdown/knockout RNA-Seq assay for COX10 is not available on ENCORE database.





47 RBPs can affect the gene expression of COX10 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COX10ENSG00000006695.6364.86740550.14110-0.592403.419202.83640HepG2AKAP1
COX10ENSG00000006695.6322.24110497.60230-0.626904.824203.95890HepG2AUH
COX10ENSG00000006695.6310.47900403.91460-0.379601.980701.31910HepG2CALR
COX10ENSG00000006695.6228.33660347.88390-0.607402.518801.79050HepG2CNOT7
COX10ENSG00000006695.6317.52910408.80690-0.364502.178401.50840HepG2DAZAP1
COX10ENSG00000006695.6300.15230526.97080-0.812006.443305.52930HepG2DDX3X
COX10ENSG00000006695.6252.45270435.16950-0.785605.460704.64400HepG2EIF2S1
COX10ENSG00000006695.6332.96550485.27340-0.543403.260102.51140HepG2FXR1
COX10ENSG00000006695.6255.28600450.12130-0.818206.042805.07690HepG2G3BP1
COX10ENSG00000006695.6211.90630322.07100-0.604002.628701.54710HepG2GRSF1
COX10ENSG00000006695.6239.61870325.78140-0.443201.977501.38060HepG2HNRNPC
COX10ENSG00000006695.6258.64610348.49580-0.430202.197601.34930HepG2HNRNPM
COX10ENSG00000006695.6320.26700460.21810-0.523002.445301.51390HepG2KHSRP
COX10ENSG00000006695.6386.01270520.70720-0.431802.075601.36410HepG2LARP4
COX10ENSG00000006695.6357.71990488.14750-0.448502.173801.61130HepG2MATR3
COX10ENSG00000006695.6271.35410408.78670-0.591203.908102.95110HepG2MSI2
COX10ENSG00000006695.6325.89780499.63580-0.616503.933603.18170HepG2NCBP2
COX10ENSG00000006695.6312.50680444.91090-0.509602.871302.13650HepG2PABPC4
COX10ENSG00000006695.6392.01580481.96280-0.298001.835201.37190HepG2PTBP1
COX10ENSG00000006695.6620.50130480.580700.368602.459701.64690HepG2RBM15
COX10ENSG00000006695.6338.39440536.37210-0.664506.574905.80080HepG2NELFE
COX10ENSG00000006695.6383.85750499.56890-0.380102.561801.96470HepG2RECQL
COX10ENSG00000006695.6635.85100430.523000.562504.127903.32040HepG2RPLP0
COX10ENSG00000006695.6194.58810294.85900-0.599602.922602.10200HepG2RPS2
COX10ENSG00000006695.6331.97190523.74690-0.657806.604105.94920HepG2SRSF1
COX10ENSG00000006695.6492.95390392.618900.328201.992601.39110HepG2SRSF7
COX10ENSG00000006695.6221.34800314.49140-0.506702.817102.31290HepG2TIAL1
COX10ENSG00000006695.6519.89980257.084001.015902.900101.88660HepG2U2AF2
COX10ENSG00000006695.6617.02540380.040300.699108.623907.66120HepG2UTP3
COX10ENSG00000006695.6307.24820431.46980-0.489903.884103.11120HepG2ZC3H8
COX10ENSG00000006695.6344.23670432.92430-0.330702.219201.71430HepG2ZNF622
COX10ENSG00000006695.6908.24170641.392500.501804.033703.35120K562AQR
COX10ENSG00000006695.6492.03010665.73730-0.436203.352502.48720K562CPSF6
COX10ENSG00000006695.6784.20400617.745100.344102.763201.89040K562DKC1
COX10ENSG00000006695.6262.83460390.42720-0.570902.718901.45220K562EEF2
COX10ENSG00000006695.6377.14100288.575400.386102.155301.44650K562EIF3G
COX10ENSG00000006695.6523.84920353.530100.567204.313003.28870K562EIF4A3
COX10ENSG00000006695.6519.86710677.31950-0.381702.046701.30720K562FMR1
COX10ENSG00000006695.6490.61420635.63690-0.373602.342001.61050K562GPKOW
COX10ENSG00000006695.6463.50600736.17040-0.667506.653705.47540K562GRSF1
COX10ENSG00000006695.6905.86180682.454100.408503.107802.13470K562MBNL1
COX10ENSG00000006695.6356.28920584.00190-0.712908.596307.24380K562MTPAP
COX10ENSG00000006695.6378.39630500.57020-0.403702.541101.77640K562POLR2G
COX10ENSG00000006695.6731.55260569.341800.361602.094301.60930K562PUS1
COX10ENSG00000006695.6644.97300446.023700.532004.273602.91670K562SAFB
COX10ENSG00000006695.6640.51620461.135200.473903.232401.66050K562SDAD1
COX10ENSG00000006695.6664.43260906.47310-0.448103.409601.87530K562SSRP1
COX10ENSG00000006695.6498.82370688.06510-0.464004.910003.98360K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COX10 is not available on ENCORE database.





3 RBPs can affect the splicing of COX10 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOX10ENSG00000006695.6chr17+140054341400555913977639139777731406319314063264-0.167000.005720.05191excludedK562AQR
SECOX10ENSG00000006695.6chr17+140054341400555913980051139803731406319314063264-0.202000.003220.05807excludedK562U2AF1
MXECOX10ENSG00000006695.6chr17+13980051139803731400543414005559139776391397777314063193140632640.191000.001390.025611includedK562U2AF1
MXECOX10ENSG00000006695.6chr17+13980051139803731400543414005559139776391397777314063193140632640.180000.003250.040671includedK562U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COX10 is not avaliable on ENCORE database.