NFYC

General Information

Gene Name       : NFYC
Gene ID             : ENSG00000066136.20
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NFYC)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NFYCENSG00000066136.2044.0135.7039.86ENCSR000AEF
HepG2NFYCENSG00000066136.2051.4235.3843.40ENCSR985KAT
K562NFYCENSG00000066136.2047.0237.8342.42ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NFYC is not avaliable on ENCORE database.



Proteins bound to RNA
  • NFYC RNA is bound by 23 proteins.  







eCLIP assay for NFYC is not avaliable on ENCORE database.





23 proteins are bound to NFYC RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr14123685341236937+3'-UTR,intron-Distal3.028804.11240K562TIA1
chr14123670641236762+3'-UTR,intron-Distal,polyA_signal3.082214.13941K562IGF2BP1
chr14123671241236757+3'-UTR,intron-Distal3.890143.19904K562TIA1
chr14123699441237076+3'-UTR,CDS,intron-Proximal3.913366.12308K562PUM2
chr14115779741157885+5'-UTR,intron-Distal,intron-Proximal3.155843.61506K562NONO
chr14115795541158070+5'-UTR,intron-Distal,intron-Proximal4.271233.99137K562NONO
chr14117518641175240+5'-UTR,intron-Distal3.102883.94979HepG2BCLAF1
chr14117503641175105+5'-UTR,intron-Distal3.349873.76820HepG2NCBP2
chr14115775541157842+5'-UTR,intron-Distal3.509653.29548K562XRN2
chr14115737241157550+5'-UTR,intron-Proximal4.184156.02664K562DDX3X
chr14120044441200542+5'-UTR,intron-Distal4.452554.17759HepG2QKI
chr14115792541158059+5'-UTR,intron-Distal,intron-Proximal4.258484.19345HepG2CSTF2T
chr14121319941213283+CDS,intron-Distal,intron-Proximal4.346597.49468HepG2BCLAF1
chr14123633041236392+CDS,intron-Distal,intron-Proximal3.615755.04653K562SF3B4
chr14122870041228755+CDS,intron-Proximal4.632109.61639HepG2PRPF8
chr14121885741218933+CDS,intron-Distal,intron-Proximal3.560366.81726HepG2GRWD1
chr14123603841236095+CDS,intron-Distal,intron-Proximal5.461417.23718K562AQR
chr14122860541228692+CDS,intron-Proximal3.945183.39858K562IGF2BP2
chr14123508041235134+CDS,intron-Distal,intron-Proximal3.737579.06608K562AQR
chr14123231541232377+CDS,intron-Proximal4.243173.98311K562IGF2BP1
chr14123497541235060+CDS,intron-Distal,intron-Proximal4.311914.69223K562SF3B4
chr14122375841223825+CDS,intron-Proximal3.578236.50179HepG2BUD13
chr14121890941218963+CDS,intron-Distal,intron-Proximal4.752466.26248HepG2PRPF8
chr14123237441232418+CDS,intron-Proximal5.049856.22530K562AQR
chr14123507741235193+CDS,intron-Distal,intron-Proximal3.164377.74688HepG2PRPF8
chr14123263941232690+CDS,intron-Distal,intron-Proximal3.324933.54718K562PRPF8
chr14123643941236497+CDS,intron-Distal3.730903.34184HepG2GRWD1
chr14123227141232378+CDS,intron-Proximal3.278116.59473HepG2GRWD1
chr14123222841232291+CDS,intron-Proximal4.2756310.16714K562AQR
chr14121994041219978+intron-Distal3.630233.41711K562DROSHA
chr14122334441223431+intron-Distal4.803966.92775K562DROSHA
chr14123441341234496+intron-Distal3.555064.97118HepG2U2AF2
chr14122290341222961+intron-Distal3.990365.73918K562DGCR8
chr14122269541222736+intron-Distal4.665615.47789K562DGCR8
chr14122290741222955+intron-Distal5.507675.19464K562DROSHA
chr14122267841222740+intron-Distal4.337754.85687K562DROSHA
chr14122361541223678+intron-Distal5.896478.88555K562DROSHA
chr14122290141222959+intron-Distal5.232129.75847HepG2DROSHA
chr14122362241223696+intron-Distal,intron-Proximal3.422566.42594HepG2DROSHA
chr14122285041222861+intron-Distal4.945238.03514HepG2DGCR8
chr14122428441224366+intron-Distal4.461485.29390K562TARDBP
chr14121997841220037+intron-Distal4.748755.36494K562DROSHA
chr14122299441223035+intron-Distal6.6513218.27461K562DGCR8
chr14122286141222896+intron-Distal5.5280412.87980HepG2DGCR8
chr14122005341220089+intron-Distal8.3961278.94365K562DGCR8
chr14122333341223416+intron-Distal5.7722411.72800K562DGCR8
chr14122313641223207+intron-Distal6.3987513.64593K562DGCR8
chr14122008941220108+intron-Distal8.3213775.40523K562DGCR8
chr14121933541219379+intron-Distal4.151323.10925K562DGCR8
chr14122266941222733+intron-Distal3.306147.74417HepG2DROSHA
chr14122269041222726+intron-Distal3.835326.25837HepG2DGCR8
chr14115761341157673+intron-Distal,intron-Proximal4.110263.98553K562NONO
chr14122348841223532+intron-Distal4.421655.18638HepG2DROSHA
chr14122030541220338+intron-Distal4.982816.41859K562DGCR8
chr14123512341235181+intron-Distal,intron-Proximal4.4954010.03412HepG2EFTUD2
chr14116304941163102+intron-Distal3.219383.42785HepG2HNRNPM
chr14123513441235193+intron-Distal,intron-Proximal4.469216.48405K562AQR
chr14122299741223032+intron-Distal6.7823324.38474HepG2DGCR8
chr14122304241223184+intron-Distal3.443305.11891HepG2GRWD1
chr14122290141222953+intron-Distal4.387499.10912HepG2DGCR8
chr14122309441223228+intron-Distal6.3052121.92479HepG2DGCR8
chr14122030141220355+intron-Distal3.276903.98694HepG2DROSHA
chr14122310741223190+intron-Distal4.638334.70044HepG2DROSHA
chr14121983741219889+intron-Distal4.248755.59743K562DROSHA
chr14123510041235195+intron-Distal,intron-Proximal3.177914.14020K562BUD13
chr14122006341220108+intron-Distal7.9915854.97717HepG2DGCR8
chr14123509441235191+intron-Distal,intron-Proximal4.009585.85871K562EFTUD2
chr14122283841222901+intron-Distal4.265966.68663HepG2DROSHA
chr14122332341223427+intron-Distal6.1028319.41075HepG2DGCR8
chr14122005141220063+intron-Distal6.5597821.37170HepG2DGCR8
chr14122048241220541+intron-Distal4.437865.45942HepG2DROSHA
chr14122276341222786+intron-Distal4.308743.96814HepG2DROSHA
chr14119020141190305+intron-Distal3.128873.73266K562KHSRP
chr14122285141222891+intron-Distal3.994866.31854K562DGCR8
chr14121991541220077+intron-Distal6.0787818.66467HepG2DROSHA
chr14122940441229490+intron-Distal4.651574.64001HepG2U2AF2
chr14119132541191380+intron-Distal4.697335.20135HepG2QKI
chr14122396841224062+intron-Proximal4.582403.62536K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NFYC is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NFYC is not available on ENCORE database.

  • 82 RBPs can affect the levels of NFYC.  








The Knockdown/knockout RNA-Seq assay for NFYC is not available on ENCORE database.





82 RBPs can affect the gene expression of NFYC :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NFYCENSG00000066136.151457.307201055.817500.464803.445802.39840HepG2ABCF1
NFYCENSG00000066136.15868.47530488.854000.829006.061204.66000HepG2ADAR
NFYCENSG00000066136.15435.44890898.13770-1.044407.285406.46690HepG2AKAP1
NFYCENSG00000066136.15540.27430719.20900-0.412702.428801.44950HepG2AKAP8
NFYCENSG00000066136.15854.313101116.42580-0.386104.463503.62780HepG2AUH
NFYCENSG00000066136.151121.36060881.777800.346702.573301.99330HepG2BOP1
NFYCENSG00000066136.15502.83610706.37920-0.490404.126003.20850HepG2CALR
NFYCENSG00000066136.151007.35900705.991400.512804.088903.15850HepG2CIRBP
NFYCENSG00000066136.15865.77790715.132100.275702.602701.95310HepG2CKAP4
NFYCENSG00000066136.15683.84910861.75340-0.333603.248702.45600HepG2DAZAP1
NFYCENSG00000066136.15797.40140661.539100.269402.448301.65940HepG2DDX19B
NFYCENSG00000066136.15756.86570549.855300.460903.561002.79900HepG2DDX21
NFYCENSG00000066136.15459.42880646.42240-0.492603.313002.47750HepG2DDX55
NFYCENSG00000066136.15498.61060739.24420-0.568102.974302.33610HepG2DDX6
NFYCENSG00000066136.151050.79480684.337200.618609.699408.58970HepG2DKC1
NFYCENSG00000066136.15635.79770487.919100.381803.259902.56250HepG2DNAJC2
NFYCENSG00000066136.15930.86870656.293400.504103.659702.61120HepG2EEF2
NFYCENSG00000066136.15346.07030537.99710-0.636504.838403.19570HepG2FKBP4
NFYCENSG00000066136.151063.25580780.374100.446203.270602.29790HepG2G3BP2
NFYCENSG00000066136.15773.25520474.284600.705106.427005.06310HepG2GEMIN5
NFYCENSG00000066136.151008.12690496.957801.0204015.8630014.52270HepG2HNRNPA1
NFYCENSG00000066136.15781.89510552.781700.500203.952103.13440HepG2HNRNPC
NFYCENSG00000066136.15773.05660549.126400.493305.840104.98710HepG2HNRNPU
NFYCENSG00000066136.151471.71870792.628500.8927010.597509.34020HepG2MAGOH
NFYCENSG00000066136.15650.42970862.74070-0.407503.189402.32320HepG2MSI2
NFYCENSG00000066136.15712.40910477.971400.575702.956201.45620HepG2NOLC1
NFYCENSG00000066136.15712.28340851.70760-0.257902.090701.55140HepG2PCBP1
NFYCENSG00000066136.15721.87970489.775500.559506.310905.23030HepG2PPIL4
NFYCENSG00000066136.151054.52770815.755600.370303.219802.58310HepG2PUF60
NFYCENSG00000066136.151032.85610866.008300.254102.919002.31350HepG2PUM1
NFYCENSG00000066136.15686.73320865.34610-0.333502.311801.69710HepG2PUM2
NFYCENSG00000066136.151388.44320728.567900.9302026.5228024.97500HepG2PUS1
NFYCENSG00000066136.15743.34640938.59100-0.336502.759502.13530HepG2QKI
NFYCENSG00000066136.15383.16930564.68050-0.559502.249001.60850HepG2RAVER1
NFYCENSG00000066136.15717.68130456.624500.652204.803202.45590HepG2RBM14
NFYCENSG00000066136.15824.064701081.41790-0.392103.825902.83680HepG2RBM15
NFYCENSG00000066136.15613.025801071.34840-0.8054013.5096012.53770HepG2RBM22
NFYCENSG00000066136.15834.76230554.774300.589403.819502.56740HepG2RCC2
NFYCENSG00000066136.151514.90250899.018600.7527010.598009.41140HepG2RPLP0
NFYCENSG00000066136.15849.73230518.405100.712808.050807.06630HepG2RPS19
NFYCENSG00000066136.15712.16710464.045900.617803.888102.94010HepG2RPS3A
NFYCENSG00000066136.151437.222601034.723800.473902.806202.12800HepG2SF3A3
NFYCENSG00000066136.15683.92020570.268100.262102.113101.54010HepG2SMN1
NFYCENSG00000066136.15763.106501210.05120-0.6651012.6825011.81700HepG2SRFBP1
NFYCENSG00000066136.15958.43980805.497000.250702.350201.76730HepG2SRSF5
NFYCENSG00000066136.15989.45750819.904000.271102.344601.69980HepG2SRSF7
NFYCENSG00000066136.15416.92690766.20310-0.8779015.6212014.50090HepG2SRSF9
NFYCENSG00000066136.151276.863701050.615400.281303.111602.57480HepG2SSB
NFYCENSG00000066136.15570.29250846.53300-0.569906.646305.84200HepG2TAF15
NFYCENSG00000066136.151398.07840766.370500.867204.534803.19310HepG2TBRG4
NFYCENSG00000066136.15618.46030777.83560-0.330802.433601.64790HepG2TIA1
NFYCENSG00000066136.15720.41510533.548900.433103.739203.17630HepG2TIAL1
NFYCENSG00000066136.15272.34020380.05080-0.480802.825602.05820HepG2UCHL5
NFYCENSG00000066136.151133.32010917.644200.304403.372102.61370HepG2UPF1
NFYCENSG00000066136.15691.95840885.94570-0.356503.356002.70850HepG2UTP3
NFYCENSG00000066136.15932.21950633.393800.557503.659702.83420HepG2XRN2
NFYCENSG00000066136.151927.514101425.222000.435507.659206.78190K562AGGF1
NFYCENSG00000066136.151787.975101215.810800.556306.311905.48590K562AQR
NFYCENSG00000066136.151261.82620874.438200.529004.827203.66370K562BOP1
NFYCENSG00000066136.152060.131001313.251300.6495015.2738013.85710K562DDX47
NFYCENSG00000066136.15890.66960607.949500.550804.573003.38420K562EFTUD2
NFYCENSG00000066136.151296.418401057.812300.293302.930602.19400K562EIF2S2
NFYCENSG00000066136.15888.51450650.831500.449002.705601.68260K562EIF3D
NFYCENSG00000066136.15663.04580459.005700.530505.191404.11740K562EIF3G
NFYCENSG00000066136.151000.07700687.855700.539804.002603.01680K562EIF4A3
NFYCENSG00000066136.15784.19750619.462000.340102.878001.69380K562EIF4B
NFYCENSG00000066136.15829.51520600.435000.466204.576502.84470K562EWSR1
NFYCENSG00000066136.151429.812001013.791300.496005.001003.83790K562FIP1L1
NFYCENSG00000066136.15931.76950715.342900.381203.836903.14190K562FXR1
NFYCENSG00000066136.151248.18190778.647400.680708.960807.93790K562HNRNPC
NFYCENSG00000066136.15887.66980695.485400.351902.458601.39440K562HNRNPF
NFYCENSG00000066136.151286.897701043.248900.302702.295101.47970K562HNRNPU
NFYCENSG00000066136.151797.883101374.460100.387303.425702.54130K562HSPD1
NFYCENSG00000066136.151173.08480866.410000.437104.115403.03270K562METAP2
NFYCENSG00000066136.151307.68980839.359400.639602.666601.69770K562PABPN1
NFYCENSG00000066136.15721.830601032.33560-0.516203.046501.40640K562PKM
NFYCENSG00000066136.151036.36760591.607300.808709.184007.81490K562PRPF8
NFYCENSG00000066136.15859.24200615.124400.482104.691903.84910K562PTBP1
NFYCENSG00000066136.152505.620701470.705100.768608.747807.83070K562PUS1
NFYCENSG00000066136.15773.04060589.729300.390402.777701.93610K562RBM22
NFYCENSG00000066136.15834.32640637.204000.388803.135102.07250K562RCC2
NFYCENSG00000066136.15329.02810452.09920-0.458403.314701.58340K562RPS10
NFYCENSG00000066136.15868.61980602.547400.527603.435602.52270K562RPS19
NFYCENSG00000066136.151139.25640811.966500.488504.840803.40770K562SAFB
NFYCENSG00000066136.151513.96730935.589400.694302.818501.49900K562SFPQ
NFYCENSG00000066136.15986.19000603.047800.709509.087407.81510K562SRSF1
NFYCENSG00000066136.15826.45050650.476700.345302.311701.36420K562SRSF4
NFYCENSG00000066136.15726.64620569.584900.351202.226401.30500K562SRSF5
NFYCENSG00000066136.151210.30920913.906900.405204.097403.09350K562SYNCRIP
NFYCENSG00000066136.15815.44730588.694600.470003.717602.75050K562TIA1
NFYCENSG00000066136.151560.002501252.716400.316403.831602.99780K562UPF1
NFYCENSG00000066136.151439.367701071.920100.425104.412103.29810K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NFYC is not available on ENCORE database.





21 RBPs can affect the splicing of NFYC :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENFYCENSG00000066136.15chr1+4123606841236287412350274123508741236380412367650.305000.000190.00527includedK562SRSF1
SENFYCENSG00000066136.15chr1+4117835841178493411575094115753941204507412046200.129000.000000.00052includedK562XRCC6
SENFYCENSG00000066136.15chr1+4122903441229161412285594122871841232267412323590.096000.000080.01209includedK562XRCC6
SENFYCENSG00000066136.15chr1+4123606841236287412350274123508741236380412367650.225000.001750.04224includedHepG2HNRNPK
SENFYCENSG00000066136.15chr1+412360684123628741234317412350874123638041236612-0.220000.001100.01525excludedHepG2U2AF2
SENFYCENSG00000066136.15chr1+4123606841236287412350274123508741236380412367650.073000.000080.00209includedK562PUS1
SENFYCENSG00000066136.15chr1+412360684123628741234317412350874123638041236612-0.328000.000000.00001excludedHepG2SFPQ
SENFYCENSG00000066136.15chr1+4123258941232646412322674123237541235027412350870.198000.000210.02358includedHepG2DDX6
SENFYCENSG00000066136.15chr1+4123606841236287412343174123508741236380412366120.306000.000010.00059includedHepG2SRSF1
SENFYCENSG00000066136.15chr1+412360684123628741235027412350874123638041236765-0.104000.000960.02973excludedHepG2SF3A3
SENFYCENSG00000066136.15chr1+412360684123628741235027412350874123638041236765-0.118000.000420.03560excludedK562HNRNPUL1
SENFYCENSG00000066136.15chr1+412360684123628741235027412350874123638041236765-0.212000.000000.00034excludedHepG2TIAL1
SENFYCENSG00000066136.15chr1+412360684123628741234317412350874123638041236612-0.230000.000000.00000excludedHepG2HNRNPC
SENFYCENSG00000066136.15chr1+4117835841178493411575094115753941204507412046200.251000.000000.00000includedK562HNRNPC
SENFYCENSG00000066136.15chr1+412325894123264641232267412323754123502741235087-0.090000.000240.00584excludedK562HNRNPC
A3SSNFYCENSG00000066136.15chr1+4123606841237275412363804123727541235027412350870.310000.000010.00177longerHepG2SRSF1
A3SSNFYCENSG00000066136.15chr1+412360684123727541236380412372754123502741235087-0.212000.001820.04311shorterHepG2U2AF2
A3SSNFYCENSG00000066136.15chr1+412360684123727541236380412372754123502741235087-0.131000.000040.01652shorterK562HNRNPUL1
A3SSNFYCENSG00000066136.15chr1+412360684123727541236380412372754123502741235087-0.207000.000000.00086shorterHepG2TIAL1
A3SSNFYCENSG00000066136.15chr1+412360684123727541236380412372754123502741235087-0.327000.000000.00008shorterHepG2SFPQ
A3SSNFYCENSG00000066136.15chr1+4123606841237275412363804123727541235027412350870.300000.000200.02138longerK562SRSF1
A3SSNFYCENSG00000066136.15chr1+412360684123727541236380412372754123502741235087-0.220000.000000.00005shorterHepG2HNRNPC
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.229000.000010.000422includedK562DROSHA
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.150000.000870.037242includedK562LIN28B
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.188000.001840.064602includedHepG2BCCIP
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.186000.000980.026412includedK562TARDBP
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.222000.000010.000452includedHepG2SFPQ
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.202000.000230.023572includedHepG2NOL12
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.193000.002490.059382includedHepG2XRN2
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.182000.004180.073152includedHepG2DDX55
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.344000.000000.000002includedHepG2U2AF2
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.114000.001970.056082includedHepG2RBFOX2
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.234000.000000.000002includedHepG2HNRNPUL1
MXENFYCENSG00000066136.15chr1+4123226741232375412350274123508741228559412287184123638041236612-0.159000.000770.028302includedK562DHX30
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.145000.002970.043902includedK562SF3B4
MXENFYCENSG00000066136.15chr1+41204507412046204121320541213277411574144115753941215244412153580.109000.000970.022791includedK562HNRNPUL1
MXENFYCENSG00000066136.15chr1+4121524441215358412188224121891841213205412132774122379241223966-0.195000.000130.005622includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NFYC is not avaliable on ENCORE database.