TMEM173

General Information

Gene Name       : TMEM173
Gene ID             : ENSG00000184584.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM173)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM173ENSG00000184584.1217.4723.2120.34ENCSR000AEF
HepG2TMEM173ENSG00000184584.122.012.012.01ENCSR985KAT
K562TMEM173ENSG00000184584.1253.4343.5248.48ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM173 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM173 RNA is bound by 8 proteins.  







eCLIP assay for TMEM173 is not avaliable on ENCORE database.





8 proteins are bound to TMEM173 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5138861794138861889-5'-UTR,intron-Distal,intron-Proximal3.786775.85428K562DDX3X
chr5138857068138857101-CDS,intron-Distal,intron-Proximal3.831783.01428K562UCHL5
chr5138858071138858155-CDS,intron-Distal,intron-Proximal5.345477.41223K562SF3B4
chr5138857886138857944-CDS,intron-Distal,intron-Proximal3.951653.04123K562LIN28B
chr5138856000138856089-CDS,intron-Distal4.942345.65342K562AQR
chr5138858035138858133-CDS,intron-Distal,intron-Proximal3.184014.81603K562BUD13
chr5138860474138860532-CDS,intron-Distal,intron-Proximal4.311916.59856K562SF3B4
chr5138858032138858117-CDS,intron-Distal,intron-Proximal5.331157.81430K562AQR
chr5138860932138860977-intron-Distal,intron-Proximal5.181376.22530K562AQR
chr5138861567138861619-intron-Distal3.821664.95247K562PRPF8
chr5138858828138858903-intron-Distal,intron-Proximal3.351463.51696K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM173 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM173 is not available on ENCORE database.

  • 103 RBPs can affect the levels of TMEM173.  








The Knockdown/knockout RNA-Seq assay for TMEM173 is not available on ENCORE database.





103 RBPs can affect the gene expression of TMEM173 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM173ENSG00000184584.8238.1718097.943201.2819011.2895010.23700HepG2ACO1
TMEM173ENSG00000184584.8478.70140101.301002.2404026.4841025.03250HepG2AKAP1
TMEM173ENSG00000184584.8197.3810098.442101.003506.415505.29290HepG2AKAP8L
TMEM173ENSG00000184584.8179.8573083.815401.101505.373804.29640HepG2ASCC1
TMEM173ENSG00000184584.8249.58620181.424600.460102.330001.69090HepG2AUH
TMEM173ENSG00000184584.8204.02020109.877200.892704.320403.14720HepG2BCCIP
TMEM173ENSG00000184584.832.7843099.98840-1.608806.093005.24430HepG2BOP1
TMEM173ENSG00000184584.8284.08700146.447700.955805.241703.88010HepG2CCAR1
TMEM173ENSG00000184584.8153.6987097.968500.649602.757802.09290HepG2CKAP4
TMEM173ENSG00000184584.8232.88050159.539900.545602.829502.18060HepG2CELF1
TMEM173ENSG00000184584.8326.2172097.033001.7492016.1414014.75920HepG2DDX3X
TMEM173ENSG00000184584.8320.62560108.018001.5695012.9855011.46140HepG2DDX55
TMEM173ENSG00000184584.8178.8736083.366701.101304.349403.58940HepG2DDX6
TMEM173ENSG00000184584.8210.50000101.503001.052207.128206.04210HepG2DNAJC21
TMEM173ENSG00000184584.8175.9369080.129201.134605.476704.65870HepG2EIF2S1
TMEM173ENSG00000184584.8279.18770208.305100.422401.999701.47060HepG2ETF1
TMEM173ENSG00000184584.8360.1111096.320701.9024016.0389014.44550HepG2FIP1L1
TMEM173ENSG00000184584.8193.12440102.633100.911903.988402.65330HepG2FUS
TMEM173ENSG00000184584.8179.1377089.358301.003304.617403.74040HepG2FXR1
TMEM173ENSG00000184584.8204.0245082.882801.299507.805206.71780HepG2G3BP1
TMEM173ENSG00000184584.8214.7838093.758601.195806.702905.09840HepG2GNB2L1
TMEM173ENSG00000184584.8174.4480083.950101.055104.817303.91650HepG2HNRNPK
TMEM173ENSG00000184584.855.5284099.30830-0.838702.219401.64920HepG2HNRNPLL
TMEM173ENSG00000184584.8114.8818066.434900.790002.381001.49800HepG2HNRNPM
TMEM173ENSG00000184584.8205.28460113.227500.858305.278404.46170HepG2HNRNPU
TMEM173ENSG00000184584.8214.1918075.853701.497506.553704.99210HepG2METAP2
TMEM173ENSG00000184584.8137.1389077.920400.815502.743401.93840HepG2MSI2
TMEM173ENSG00000184584.8143.4478092.001500.640701.939301.40380HepG2NCBP2
TMEM173ENSG00000184584.830.4970088.05280-1.529704.360603.42670HepG2NSUN2
TMEM173ENSG00000184584.826.4742062.75700-1.245202.796001.90370HepG2PABPC1
TMEM173ENSG00000184584.8182.30310112.080900.701703.360102.43550HepG2PARN
TMEM173ENSG00000184584.8139.4458082.805200.751803.155502.51510HepG2PCBP1
TMEM173ENSG00000184584.825.9542061.57110-1.246302.974101.39550HepG2PNPT1
TMEM173ENSG00000184584.851.35050105.37730-1.037104.017503.10410HepG2PRPF4
TMEM173ENSG00000184584.8217.6641084.265401.3690010.791509.84710HepG2PTBP1
TMEM173ENSG00000184584.8237.14420172.366600.460202.200901.65950HepG2PUM1
TMEM173ENSG00000184584.8258.29330172.237500.584503.089702.38050HepG2PUM2
TMEM173ENSG00000184584.8174.71950108.686500.684802.911902.03310HepG2RBM15
TMEM173ENSG00000184584.8542.66520174.103401.6400028.1089026.80170HepG2RBM22
TMEM173ENSG00000184584.8152.7769093.772600.704102.736602.19760HepG2NELFE
TMEM173ENSG00000184584.842.1427092.11410-1.128103.289902.26020HepG2RPS10
TMEM173ENSG00000184584.8127.8045070.550300.857102.930302.30100HepG2RPS19
TMEM173ENSG00000184584.8184.77270104.318600.824703.156902.00480HepG2RPS5
TMEM173ENSG00000184584.838.0741098.29800-1.368404.452403.57550HepG2SF3B1
TMEM173ENSG00000184584.8141.1730087.716800.686402.022901.50520HepG2SF3B4
TMEM173ENSG00000184584.8177.81770117.596400.596502.697702.05930HepG2SMN1
TMEM173ENSG00000184584.8352.68550196.641400.842707.275606.56930HepG2SRFBP1
TMEM173ENSG00000184584.849.05530170.72790-1.7992013.3081012.35120HepG2SSB
TMEM173ENSG00000184584.8296.90020182.324500.703405.108304.30700HepG2SUCLG1
TMEM173ENSG00000184584.8177.8535082.316801.111306.553505.75430HepG2TAF15
TMEM173ENSG00000184584.8293.7065082.376001.8340015.5008013.96600HepG2U2AF1
TMEM173ENSG00000184584.8203.4139049.640602.034706.334904.76860HepG2U2AF2
TMEM173ENSG00000184584.859.12080104.00190-0.814902.770002.09740HepG2ZC3H8
TMEM173ENSG00000184584.8521.85980883.38050-0.759407.670406.79250K562AGGF1
TMEM173ENSG00000184584.8525.06130919.16800-0.807806.128605.13110K562AKAP8L
TMEM173ENSG00000184584.8550.410101033.38900-0.908806.809405.95480K562AQR
TMEM173ENSG00000184584.8756.64430589.375700.360302.128201.36950K562BOP1
TMEM173ENSG00000184584.8828.66820603.575700.457203.528102.30650K562CCAR1
TMEM173ENSG00000184584.8800.16050626.687800.352402.592301.83220K562CPSF6
TMEM173ENSG00000184584.81165.717001781.07200-0.611508.901807.19580K562CELF1
TMEM173ENSG00000184584.8465.78590658.09010-0.498605.163003.34280K562DDX27
TMEM173ENSG00000184584.8753.56340573.408600.394102.964801.88430K562DDX3X
TMEM173ENSG00000184584.8777.528201095.40330-0.494504.401903.60570K562DDX47
TMEM173ENSG00000184584.82650.187901015.875901.3833059.8139057.44830K562EIF2S2
TMEM173ENSG00000184584.8340.19410613.92790-0.851705.135603.72650K562EIF3A
TMEM173ENSG00000184584.8822.12830637.616100.366602.341901.55340K562FMR1
TMEM173ENSG00000184584.8309.80230492.62480-0.669106.049903.95640K562FUS
TMEM173ENSG00000184584.8158.88560384.40390-1.2746010.421308.88080K562G3BP2
TMEM173ENSG00000184584.8519.30510889.90220-0.777105.209503.67250K562GLRX3
TMEM173ENSG00000184584.8985.434101353.69070-0.458104.506303.54570K562GRSF1
TMEM173ENSG00000184584.8532.13140970.75270-0.867308.386706.60910K562HNRNPA1
TMEM173ENSG00000184584.8462.47130614.64360-0.410402.665602.07760K562HNRNPC
TMEM173ENSG00000184584.8512.54180719.93210-0.490204.160301.84050K562HNRNPH1
TMEM173ENSG00000184584.81274.36730989.879800.364402.340201.37780K562HNRNPL
TMEM173ENSG00000184584.81317.13290951.963900.468304.258003.27610K562HSPD1
TMEM173ENSG00000184584.8626.47640975.57030-0.639002.702301.88800K562KIF1C
TMEM173ENSG00000184584.8794.58110547.945500.536105.068602.91200K562LSM11
TMEM173ENSG00000184584.8522.87190684.78250-0.389202.354101.50910K562MATR3
TMEM173ENSG00000184584.81025.344301544.24410-0.590806.362804.66430K562MSI2
TMEM173ENSG00000184584.8530.39120935.59030-0.818804.850003.80190K562MTPAP
TMEM173ENSG00000184584.8554.73450766.01410-0.465602.611301.75880K562NAA15
TMEM173ENSG00000184584.81143.241301584.57250-0.471003.919402.12390K562NOL12
TMEM173ENSG00000184584.81095.03130755.314800.535702.950401.67140K562PABPC1
TMEM173ENSG00000184584.8354.81850870.30360-1.2944018.4623016.38970K562PCBP3
TMEM173ENSG00000184584.8825.05850600.042000.459303.774702.06690K562PHF6
TMEM173ENSG00000184584.8284.57070667.54940-1.2301019.4993017.48950K562POLR2G
TMEM173ENSG00000184584.8773.08110551.077500.488303.305902.30480K562PSIP1
TMEM173ENSG00000184584.8498.61350666.75810-0.419202.594801.94840K562PTBP1
TMEM173ENSG00000184584.81178.080601580.70800-0.424103.533402.61400K562PUF60
TMEM173ENSG00000184584.82263.342901647.381000.458208.118106.44770K562PUM2
TMEM173ENSG00000184584.8532.75410911.77340-0.775207.461506.61580K562PUS1
TMEM173ENSG00000184584.8222.91370366.77800-0.718402.970201.49240K562RAVER1
TMEM173ENSG00000184584.8489.99630888.21100-0.858109.013307.96720K562RBM15
TMEM173ENSG00000184584.8940.95370639.104600.558004.771603.63390K562RBM22
TMEM173ENSG00000184584.8649.16980502.715300.368802.434901.50890K562RCC2
TMEM173ENSG00000184584.8996.73710672.610700.567304.650103.19210K562NELFE
TMEM173ENSG00000184584.8399.88640548.80330-0.456704.114102.19480K562RPS10
TMEM173ENSG00000184584.8479.98410676.51710-0.495102.805701.98330K562RPS19
TMEM173ENSG00000184584.8465.19200329.079600.499302.343601.43090K562RPS3
TMEM173ENSG00000184584.8422.33740679.07830-0.685204.313702.64730K562RRP9
TMEM173ENSG00000184584.8436.88160594.81260-0.445203.025501.89440K562SAFB
TMEM173ENSG00000184584.8347.81020614.96280-0.822208.120105.72250K562SDAD1
TMEM173ENSG00000184584.8254.65970568.33080-1.158209.246206.68610K562SERBP1
TMEM173ENSG00000184584.8385.31570569.00900-0.562403.441602.35390K562SF3B1
TMEM173ENSG00000184584.8502.62330664.72080-0.403302.517001.31750K562SLBP
TMEM173ENSG00000184584.8649.34220476.568100.446203.040301.95390K562SRFBP1
TMEM173ENSG00000184584.8628.962201050.80490-0.740403.829002.74720K562SRPK2
TMEM173ENSG00000184584.8511.18460759.82880-0.571805.925903.64730K562SRSF9
TMEM173ENSG00000184584.8673.30510921.26140-0.452403.447601.90430K562SSRP1
TMEM173ENSG00000184584.8617.34900842.60030-0.448803.135901.79230K562STAU1
TMEM173ENSG00000184584.8964.837501379.20010-0.515506.259804.12490K562SUCLG1
TMEM173ENSG00000184584.8332.89420643.11530-0.950008.629506.79270K562SUPV3L1
TMEM173ENSG00000184584.8198.55470377.34180-0.926304.568702.51900K562TAF15
TMEM173ENSG00000184584.81100.26010661.476000.734008.560107.22740K562TARDBP
TMEM173ENSG00000184584.8795.96620638.095900.318802.058201.35980K562TIA1
TMEM173ENSG00000184584.8441.10820632.72520-0.520403.318201.36610K562TRNAU1AP
TMEM173ENSG00000184584.8478.15550680.58440-0.509303.357102.22790K562UCHL5
TMEM173ENSG00000184584.81603.658601102.372300.540705.593004.61070K562UPF1
TMEM173ENSG00000184584.8556.94870924.22980-0.730703.945802.30660K562UTP18
TMEM173ENSG00000184584.8591.46740943.28390-0.673404.243403.15080K562WDR3
TMEM173ENSG00000184584.8515.39920980.77720-0.928206.276205.05380K562WDR43
TMEM173ENSG00000184584.8842.637601224.11100-0.538806.115004.19360K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM173 is not available on ENCORE database.





18 RBPs can affect the splicing of TMEM173 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM173ENSG00000184584.8chr5-138856913138857100138855118138856039138857854138858789-0.199000.000030.00098excludedK562SRSF1
SETMEM173ENSG00000184584.8chr5-138856913138857100138855118138856039138857854138858789-0.163000.000640.02631excludedK562PRPF8
SETMEM173ENSG00000184584.8chr5-1388610621388612891388607701388609271388617941388618950.137000.000630.05477includedK562XRCC6
SETMEM173ENSG00000184584.8chr5-138860743138861289138860374138860483138861794138861887-0.118000.000110.03594excludedK562WDR43
SETMEM173ENSG00000184584.8chr5-138856913138857100138855118138856039138857854138858789-0.173000.000270.00404excludedK562AQR
SETMEM173ENSG00000184584.8chr5-138856913138857100138855118138856039138857854138858789-0.183000.000440.02064excludedK562FXR1
SETMEM173ENSG00000184584.8chr5-138860743138861289138860374138860483138861794138861887-0.095000.000030.00367excludedK562HNRNPL
SETMEM173ENSG00000184584.8chr5-138860743138861289138860374138860483138861794138861887-0.087000.000300.04866excludedK562ZC3H8
SETMEM173ENSG00000184584.8chr5-1388586881388587891388580461388580931388603741388604830.077000.000160.04163includedK562SAFB
SETMEM173ENSG00000184584.8chr5-138861062138861289138860770138860927138861794138861895-0.195000.000080.02561excludedK562SAFB
SETMEM173ENSG00000184584.8chr5-138856913138857100138855118138856039138857854138858789-0.154000.001000.04027excludedK562PTBP1
SETMEM173ENSG00000184584.8chr5-138860743138861289138860374138860483138861794138861887-0.100000.003200.04913excludedK562HNRNPC
A3SSTMEM173ENSG00000184584.8chr5-138860374138861289138860374138860483138861794138861887-0.171000.000130.07813shorterK562HNRNPL
A3SSTMEM173ENSG00000184584.8chr5-138860743138861289138860743138860927138861794138861887-0.275000.000020.02888shorterK562SAFB
RITMEM173ENSG00000184584.8chr5-1388607431388612891388607431388609271388610621388612890.216000.005450.09127includedK562HNRNPC
RITMEM173ENSG00000184584.8chr5-138860743138861289138860743138860927138861062138861289-0.115000.002130.02589excludedK562AGGF1
RITMEM173ENSG00000184584.8chr5-1388603741388612891388603741388604831388607431388612890.119000.001070.02508includedK562RBM22
RITMEM173ENSG00000184584.8chr5-1388607431388612891388607431388609271388610621388612890.141000.000680.04701includedK562WDR3
RITMEM173ENSG00000184584.8chr5-138860374138861289138860374138860483138860743138861289-0.107000.000090.01712excludedK562FTO
RITMEM173ENSG00000184584.8chr5-1388603741388612891388603741388604831388607431388612890.131000.007430.09585includedK562U2AF1
RITMEM173ENSG00000184584.8chr5-138860374138861289138860374138860483138860743138861289-0.095000.000650.03840excludedK562CPSF6
MXETMEM173ENSG00000184584.8chr5-1388603741388604831388607431388612891388579361388580931388617941388618870.199000.001610.045901includedK562XRN2
MXETMEM173ENSG00000184584.8chr5-138860374138860483138860743138860927138857854138858093138861794138861887-0.117000.001020.084632includedK562XRCC6
MXETMEM173ENSG00000184584.8chr5-1388607431388609271388610621388612891388603741388604831388617941388618870.229000.000000.002031includedK562WDR3
MXETMEM173ENSG00000184584.8chr5-1388603741388604831388607431388609271388578541388580931388610621388612140.138000.003790.062251includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM173 is not avaliable on ENCORE database.