ERCC6L2

General Information

Gene Name       : ERCC6L2
Gene ID             : ENSG00000182150.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ERCC6L2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ERCC6L2ENSG00000182150.1517.1215.5516.34ENCSR000AEF
HepG2ERCC6L2ENSG00000182150.1514.1617.7715.96ENCSR985KAT
K562ERCC6L2ENSG00000182150.1511.8514.5813.21ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ERCC6L2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ERCC6L2 RNA is bound by 16 proteins.  







eCLIP assay for ERCC6L2 is not avaliable on ENCORE database.





16 proteins are bound to ERCC6L2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr99871819998718302+3'-UTR,5'-UTR,CDS,intron-Proximal4.0574410.78406HepG2BCLAF1
chr99877629598776392+3'-UTR3.556724.28919HepG2KHSRP
chr99873430698734431+3'-UTR,CDS4.215044.72880HepG2GRWD1
chr99873419098734264+3'-UTR,CDS,intron-Proximal4.203684.23351K562BUD13
chr99870378398703830+5'-UTR,CDS3.413635.15500HepG2BCLAF1
chr99869104398691090+5'-UTR,CDS4.220393.02457HepG2BCLAF1
chr99867851598678583+CDS4.160683.16051HepG2PPIG
chr99864335398643447+CDS3.580345.76104HepG2BCLAF1
chr99867850898678622+CDS,intron-Proximal3.336907.66871HepG2BCLAF1
chr99866019898660251+CDS4.969146.58593HepG2BCLAF1
chr99868345498683518+CDS,intron-Proximal4.385596.65960HepG2BCLAF1
chr99869031598690397+CDS,intron-Distal,intron-Proximal4.337224.69223K562SF3B4
chr99868352198683595+CDS3.611847.83567HepG2BCLAF1
chr99869042198690432+CDS,intron-Proximal3.498593.27569HepG2BCLAF1
chr99866936398669457+CDS3.074597.20615HepG2BCLAF1
chr99864354198643562+CDS4.111843.45943HepG2BCLAF1
chr99866013898660198+CDS4.665304.78529HepG2BCLAF1
chr99867794798678011+CDS,intron-Proximal4.359827.53358HepG2BCLAF1
chr99864317198643261+CDS3.305323.61259K562ZNF622
chr99868551698685608+CDS,intron-Proximal3.063514.25713HepG2U2AF2
chr99868353498683605+CDS,intron-Proximal4.322805.13243HepG2GRWD1
chr99866733698667370+intron-Distal4.6402832.53576K562XRCC6
chr99877022298770330+intron-Distal4.487833.70058HepG2XPO5
chr99868519398685291+intron-Distal4.338824.96658K562KHSRP
chr99874447098744525+intron-Distal4.188324.24431HepG2RBFOX2
chr99866294498663088+intron-Distal4.631306.27552K562KHSRP
chr99865427998654393+intron-Distal3.966223.71397K562KHSRP
chr99873858998738658+intron-Distal4.232183.96879HepG2MATR3
chr99868419198684247+intron-Distal3.483055.58362HepG2U2AF2
chr99869245698692504+intron-Distal4.290864.51299HepG2SUGP2
chr99866540698665538+intron-Distal3.233064.08064K562KHSRP
chr99866731898667366+intron-Distal4.581304.51051K562TBRG4
chr99869250498692562+intron-Distal3.477534.08528HepG2SUGP2
chr99865183198651922+intron-Distal4.517194.17759HepG2QKI
chr99872289798722952+intron-Distal3.936503.24150HepG2HLTF
chr99870123898701313+intron-Distal3.796253.04224HepG2SUGP2
chr99866731898667336+intron-Distal4.5554631.26178K562XRCC6
chr99874418598744256+intron-Distal5.072795.31214HepG2XPO5
chr99873857198738648+intron-Distal3.228784.18137HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ERCC6L2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ERCC6L2 is not available on ENCORE database.

  • 62 RBPs can affect the levels of ERCC6L2.  








The Knockdown/knockout RNA-Seq assay for ERCC6L2 is not available on ENCORE database.





62 RBPs can affect the gene expression of ERCC6L2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ERCC6L2ENSG00000182150.11316.68080436.10390-0.461602.353401.62560HepG2ASCC1
ERCC6L2ENSG00000182150.11188.41170364.27270-0.951105.552304.20720HepG2BCCIP
ERCC6L2ENSG00000182150.11400.40850510.57990-0.350701.829501.33380HepG2BOP1
ERCC6L2ENSG00000182150.11288.47350385.49790-0.418302.549301.86970HepG2DNAJC21
ERCC6L2ENSG00000182150.11283.26400382.11810-0.431903.080702.39840HepG2DNAJC2
ERCC6L2ENSG00000182150.11305.78870416.93470-0.447302.145801.61640HepG2EIF2S1
ERCC6L2ENSG00000182150.11672.68940448.622300.584302.876802.17630HepG2EIF4B
ERCC6L2ENSG00000182150.11950.69680751.431000.339203.293102.64640HepG2ETF1
ERCC6L2ENSG00000182150.11301.26960432.91150-0.523003.034502.31280HepG2HNRNPC
ERCC6L2ENSG00000182150.11303.30570430.04880-0.503704.017303.29790HepG2HNRNPU
ERCC6L2ENSG00000182150.11338.26200439.27920-0.377002.967602.21030HepG2ILF2
ERCC6L2ENSG00000182150.11719.12070465.064700.628704.886904.02280HepG2MAGOH
ERCC6L2ENSG00000182150.11488.37480385.416600.341502.181701.63220HepG2PCBP1
ERCC6L2ENSG00000182150.11394.04470276.362000.511702.834502.01540HepG2PRPF8
ERCC6L2ENSG00000182150.11538.74170392.157800.458103.684103.07230HepG2PTBP1
ERCC6L2ENSG00000182150.11346.87240467.17230-0.429502.630302.04710HepG2PUF60
ERCC6L2ENSG00000182150.11597.29700424.754900.491703.812403.09570HepG2QKI
ERCC6L2ENSG00000182150.11661.22130426.060900.634002.970302.24110HepG2RAVER1
ERCC6L2ENSG00000182150.11508.70060628.05900-0.304102.106501.63860HepG2RBM22
ERCC6L2ENSG00000182150.11655.92830385.477900.766808.084606.98380HepG2RBM25
ERCC6L2ENSG00000182150.11277.43240382.97270-0.465103.264102.57510HepG2SAFB2
ERCC6L2ENSG00000182150.11701.98860501.917000.483903.527802.74070HepG2SF3B1
ERCC6L2ENSG00000182150.11543.16540408.319100.411602.948202.34190HepG2SF3B4
ERCC6L2ENSG00000182150.11789.33410540.057600.547403.429802.30270HepG2SRSF3
ERCC6L2ENSG00000182150.11430.52720346.711800.312301.825801.35970HepG2SRSF9
ERCC6L2ENSG00000182150.11240.22380342.75380-0.512802.413001.39520HepG2STIP1
ERCC6L2ENSG00000182150.11630.87480524.579800.266101.827101.30240HepG2SUCLG1
ERCC6L2ENSG00000182150.11279.37490494.24040-0.823006.871605.79850HepG2TARDBP
ERCC6L2ENSG00000182150.11283.12860417.84240-0.561504.104803.52150HepG2TIAL1
ERCC6L2ENSG00000182150.11749.66090455.110200.719906.654805.69370HepG2U2AF1
ERCC6L2ENSG00000182150.11127.39590210.64070-0.725503.206202.39020HepG2UCHL5
ERCC6L2ENSG00000182150.11185.04170326.55420-0.819503.577802.42640HepG2UPF2
ERCC6L2ENSG00000182150.11612.35890418.834100.547902.674201.43990HepG2XRCC5
ERCC6L2ENSG00000182150.11161.55530350.98130-1.119407.747706.54610HepG2XRN2
ERCC6L2ENSG00000182150.11256.26350520.44600-1.0221013.5182012.36680K562AGGF1
ERCC6L2ENSG00000182150.11378.77870571.83400-0.594205.104903.67240K562AKAP8
ERCC6L2ENSG00000182150.11305.00880541.53350-0.828208.059206.88820K562AKAP8L
ERCC6L2ENSG00000182150.11441.44500568.17230-0.364102.778601.86330K562ATP5C1
ERCC6L2ENSG00000182150.11634.32910801.15450-0.336802.718601.62170K562CPEB4
ERCC6L2ENSG00000182150.11600.13820304.941300.9767011.231509.55270K562EIF4A3
ERCC6L2ENSG00000182150.11435.16910613.17330-0.494703.579602.60500K562FIP1L1
ERCC6L2ENSG00000182150.11434.24690317.121300.453401.965201.43840K562FXR1
ERCC6L2ENSG00000182150.11464.30390342.691700.438102.014901.42420K562G3BP2
ERCC6L2ENSG00000182150.11359.56700512.89150-0.512403.452102.56800K562GPKOW
ERCC6L2ENSG00000182150.11500.30270749.20770-0.582605.673404.10760K562HNRNPL
ERCC6L2ENSG00000182150.11564.45210831.32570-0.558604.860903.81420K562HSPD1
ERCC6L2ENSG00000182150.11325.80720482.27150-0.565803.181702.05520K562IGF2BP2
ERCC6L2ENSG00000182150.11358.68050574.75190-0.680205.899604.59080K562KIF1C
ERCC6L2ENSG00000182150.11351.35950550.13880-0.646805.056803.46040K562MAK16
ERCC6L2ENSG00000182150.11454.61790643.86040-0.502104.241703.07580K562MBNL1
ERCC6L2ENSG00000182150.11289.94850451.29510-0.638303.421802.41990K562NAA15
ERCC6L2ENSG00000182150.11487.73630643.56140-0.400003.890703.02370K562NSUN2
ERCC6L2ENSG00000182150.11245.58460425.82100-0.794003.117002.05070K562PABPN1
ERCC6L2ENSG00000182150.11444.39590696.08040-0.647405.883304.61220K562PPIG
ERCC6L2ENSG00000182150.11341.38000537.15370-0.654005.140004.42820K562PUS1
ERCC6L2ENSG00000182150.11277.48750523.29160-0.9152010.716309.57260K562RBM15
ERCC6L2ENSG00000182150.11338.39220472.02030-0.480203.129902.23000K562RBM22
ERCC6L2ENSG00000182150.11372.26730495.90090-0.413703.212601.94540K562SRSF7
ERCC6L2ENSG00000182150.11366.75530471.17720-0.361502.050301.35290K562TIA1
ERCC6L2ENSG00000182150.11329.10070462.43260-0.490702.932201.79990K562TRA2A
ERCC6L2ENSG00000182150.11215.45750302.48270-0.489402.227801.39250K562TRIM56
ERCC6L2ENSG00000182150.11465.53970332.387400.485902.315101.32670K562U2AF1
ERCC6L2ENSG00000182150.11507.13670343.215900.563204.736403.69050K562U2AF2
ERCC6L2ENSG00000182150.11514.37740682.38060-0.407703.826802.99370K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ERCC6L2 is not available on ENCORE database.





4 RBPs can affect the splicing of ERCC6L2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEERCC6L2ENSG00000182150.11chr9+9873382598733877987328579873293898734214987342500.263000.004290.06712includedK562SRSF1
SEERCC6L2ENSG00000182150.11chr9+9872974098729907987288439872899698732857987329380.299000.000100.00285includedHepG2U2AF1
SEERCC6L2ENSG00000182150.11chr9+9872974098729907987288439872899698732857987329380.638000.000000.00000includedHepG2U2AF2
SEERCC6L2ENSG00000182150.11chr9+987338259873387798732857987329389873421498734250-0.238000.006330.06402excludedHepG2U2AF2
SEERCC6L2ENSG00000182150.11chr9+9872974098729907987287519872899698732857987329380.326000.000050.01273includedK562NSUN2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ERCC6L2 is not avaliable on ENCORE database.