UBE2B

General Information

Gene Name       : UBE2B
Gene ID             : ENSG00000119048.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: UBE2B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UBE2BENSG00000119048.747.6946.1546.92ENCSR000AEF
HepG2UBE2BENSG00000119048.733.8083.2858.54ENCSR985KAT
K562UBE2BENSG00000119048.751.7159.7955.75ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for UBE2B is not avaliable on ENCORE database.



Proteins bound to RNA
  • UBE2B RNA is bound by 24 proteins.  







eCLIP assay for UBE2B is not avaliable on ENCORE database.





24 proteins are bound to UBE2B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5133726267133726345+3'-UTR4.4376719.52653HepG2FUBP3
chr5133726233133726272+3'-UTR3.9732320.76665K562KHSRP
chr5133725903133725973+3'-UTR,CDS,intron-Proximal4.6782717.58659K562U2AF1
chr5133725904133725982+3'-UTR,CDS,intron-Proximal4.4135526.58868K562U2AF2
chr5133726214133726344+3'-UTR6.6527516.26320HepG2SUB1
chr5133726211133726267+3'-UTR4.6960311.42010HepG2FUBP3
chr5133725914133725930+3'-UTR,CDS,intron-Proximal3.0015414.24943K562YBX3
chr5133726263133726336+3'-UTR3.3802010.80134K562DDX6
chr5133723995133724048+3'-UTR,CDS,intron-Distal,intron-Proximal4.6852117.20083K562SF3B4
chr5133726168133726182+3'-UTR4.139093.89838K562PABPC4
chr5133726392133726434+3'-UTR5.107615.66249K562TIA1
chr5133726182133726212+3'-UTR4.867218.19301K562PABPC4
chr5133726218133726332+3'-UTR4.0808250.18087K562PUM2
chr5133726209133726233+3'-UTR4.1439820.91589K562KHSRP
chr5133726210133726324+3'-UTR3.118469.28848K562RBFOX2
chr5133726227133726283+3'-UTR3.862685.93564K562NOLC1
chr5133724079133724104+3'-UTR,CDS,intron-Distal4.1714715.73774K562YBX3
chr5133707253133707265+5'-UTR4.3614916.98940K562NCBP2
chr5133707153133707204+5'-UTR3.675233.53770HepG2DDX3X
chr5133707275133707318+5'-UTR,CDS3.276624.39512K562HNRNPC
chr5133707254133707299+5'-UTR,CDS3.593416.89681K562PABPC4
chr5133707205133707247+5'-UTR4.216463.99162HepG2DDX3X
chr5133707265133707294+5'-UTR,CDS4.2640717.67685K562NCBP2
chr5133707279133707310+5'-UTR,CDS3.2746020.96126K562DDX6
chr5133707244133707275+5'-UTR3.175543.94332K562HNRNPC
chr5133712323133712442+CDS,intron-Distal,intron-Proximal4.232919.03062K562AQR
chr5133710152133710241+CDS,intron-Proximal3.105416.61836K562AQR
chr5133710070133710162+CDS,intron-Proximal3.496858.66760K562UCHL5
chr5133712373133712388+CDS,intron-Distal,intron-Proximal3.587083.67576K562IGF2BP2
chr5133707305133707339+CDS,intron-Proximal3.587303.87268K562SRSF1
chr5133716398133716432+CDS,intron-Distal,intron-Proximal4.470284.12401HepG2U2AF2
chr5133710073133710122+CDS,intron-Proximal3.743705.11124K562DDX6
chr5133716479133716533+CDS,intron-Distal,intron-Proximal4.821665.82778K562PRPF8
chr5133712340133712423+CDS,intron-Distal,intron-Proximal3.6085510.15139K562EFTUD2
chr5133710148133710247+CDS,intron-Proximal3.816734.65388K562PRPF8
chr5133712349133712396+CDS,intron-Distal,intron-Proximal3.262625.03700K562U2AF1
chr5133712351133712393+CDS,intron-Distal,intron-Proximal4.196974.89971K562U2AF2
chr5133707310133707331+CDS,intron-Proximal3.993667.45535K562DDX6
chr5133712346133712393+CDS,intron-Distal,intron-Proximal3.651573.32861HepG2U2AF2
chr5133720736133720764+intron-Distal3.047095.43929K562KHSRP
chr5133710162133710260+intron-Distal,intron-Proximal5.308095.43043K562EFTUD2
chr5133725790133725847+intron-Distal,intron-Proximal3.607047.14496K562KHSRP
chr5133723961133723995+intron-Distal,intron-Proximal5.4694317.59328K562SF3B4
chr5133714151133714221+intron-Distal3.975505.11169HepG2ILF3
chr5133712186133712240+intron-Distal5.134226.29945HepG2XPO5
chr5133724230133724292+intron-Distal4.701345.47569HepG2U2AF2
chr5133714135133714203+intron-Distal4.282714.58544K562ILF3
chr5133724223133724284+intron-Distal3.807285.36788K562U2AF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for UBE2B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for UBE2B is not available on ENCORE database.

  • 71 RBPs can affect the levels of UBE2B.  








The Knockdown/knockout RNA-Seq assay for UBE2B is not available on ENCORE database.





71 RBPs can affect the gene expression of UBE2B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
UBE2BENSG00000119048.31093.52080823.536600.409005.501704.70210HepG2ACO1
UBE2BENSG00000119048.32163.693401489.882000.538204.491603.83590HepG2AKAP1
UBE2BENSG00000119048.3525.39520744.60070-0.503102.994902.05820HepG2BCLAF1
UBE2BENSG00000119048.3869.028601171.18690-0.430503.256502.42110HepG2CIRBP
UBE2BENSG00000119048.31532.438701275.824600.264302.152101.57400HepG2CELF1
UBE2BENSG00000119048.3353.50200639.38210-0.855003.835503.04970HepG2DDX21
UBE2BENSG00000119048.31164.61350700.897000.732504.240303.04520HepG2DDX59
UBE2BENSG00000119048.3315.41710675.14500-1.0979022.6050020.90240HepG2DNAJC2
UBE2BENSG00000119048.3814.04350588.235700.468602.619901.54650HepG2AGO1
UBE2BENSG00000119048.3829.416301178.53450-0.506804.147103.42970HepG2EIF2S1
UBE2BENSG00000119048.3919.420101302.37030-0.502303.694902.95980HepG2EIF4A3
UBE2BENSG00000119048.3787.213001219.02140-0.630905.750004.80430HepG2G3BP1
UBE2BENSG00000119048.3364.03830699.68760-0.942609.021907.90930HepG2GPKOW
UBE2BENSG00000119048.3861.425901234.55110-0.519204.823403.92130HepG2HNRNPK
UBE2BENSG00000119048.3919.923201249.87920-0.442207.764906.68550HepG2HNRNPL
UBE2BENSG00000119048.3915.944701239.08100-0.435903.265902.53830HepG2IGF2BP2
UBE2BENSG00000119048.3549.57550714.66220-0.378902.434201.67330HepG2MSI2
UBE2BENSG00000119048.31037.950001353.09860-0.382502.599701.98430HepG2NCBP2
UBE2BENSG00000119048.3904.513401360.49310-0.588906.232705.09080HepG2NOL12
UBE2BENSG00000119048.3843.108401204.93280-0.515204.203803.32530HepG2PABPC4
UBE2BENSG00000119048.3971.614901168.79600-0.266601.850201.33670HepG2PCBP1
UBE2BENSG00000119048.3527.47890756.86730-0.520903.149601.35600HepG2PHF6
UBE2BENSG00000119048.3329.09520461.10260-0.486603.319501.96590HepG2PKM
UBE2BENSG00000119048.3523.55580677.78620-0.372503.079202.30520HepG2PPIL4
UBE2BENSG00000119048.31050.511401298.65220-0.305901.801701.30700HepG2PUF60
UBE2BENSG00000119048.31003.052101377.54420-0.457705.686304.73710HepG2PUM2
UBE2BENSG00000119048.3609.874201288.05210-1.0786024.2203022.63620HepG2QKI
UBE2BENSG00000119048.31582.19600838.098400.916606.720105.64700HepG2RAVER1
UBE2BENSG00000119048.31025.071401323.56480-0.368704.437503.78110HepG2NELFE
UBE2BENSG00000119048.3946.411001232.69510-0.381304.716303.94090HepG2RECQL
UBE2BENSG00000119048.3414.78030542.52190-0.387302.351101.77940HepG2RPS19
UBE2BENSG00000119048.3764.800501210.57260-0.662505.050403.97070HepG2RPS3A
UBE2BENSG00000119048.3870.27620643.059300.436402.958502.14870HepG2RRP9
UBE2BENSG00000119048.3470.08850676.74890-0.525706.164805.26170HepG2SAFB2
UBE2BENSG00000119048.31131.29000864.795700.387401.948301.38010HepG2SF3A3
UBE2BENSG00000119048.3931.015301245.06650-0.419306.815805.79390HepG2SLBP
UBE2BENSG00000119048.31097.07810735.391100.577003.344902.48070HepG2SNRNP70
UBE2BENSG00000119048.32433.308401394.388300.8032028.0066026.84740HepG2SRFBP1
UBE2BENSG00000119048.3968.64860711.125300.445802.558601.59950HepG2SRSF3
UBE2BENSG00000119048.31168.149901458.22590-0.320004.693903.92120HepG2SUCLG1
UBE2BENSG00000119048.3405.50160650.77050-0.682405.881904.88270HepG2TARDBP
UBE2BENSG00000119048.3855.627401067.43000-0.319102.590301.77900HepG2TIA1
UBE2BENSG00000119048.3520.14960738.47310-0.505604.922304.29460HepG2TIAL1
UBE2BENSG00000119048.3523.49690744.99450-0.509006.125605.34460HepG2TRIM56
UBE2BENSG00000119048.31006.805101268.61800-0.333502.980702.06950HepG2TUFM
UBE2BENSG00000119048.31193.47750755.321800.659905.994805.08620HepG2U2AF1
UBE2BENSG00000119048.3682.05070495.469200.461003.380802.54590HepG2UCHL5
UBE2BENSG00000119048.3490.60460766.93880-0.644609.359408.20570HepG2UPF1
UBE2BENSG00000119048.3637.73720788.32640-0.305802.534201.52560HepG2UTP18
UBE2BENSG00000119048.3590.04280823.99800-0.481802.513201.31990HepG2XRCC5
UBE2BENSG00000119048.3601.53180825.58020-0.456802.567201.86770HepG2XRN2
UBE2BENSG00000119048.31030.17100843.489700.288303.219002.64290HepG2ZNF622
UBE2BENSG00000119048.31682.248101165.988200.528705.526404.76750K562AGGF1
UBE2BENSG00000119048.31752.956301281.266800.452104.838203.45080K562AKAP8
UBE2BENSG00000119048.31568.837401213.269000.370703.366602.64480K562AKAP8L
UBE2BENSG00000119048.32394.097801328.924000.8491014.2318013.04650K562AQR
UBE2BENSG00000119048.32245.781601748.568500.360904.274103.05260K562CELF1
UBE2BENSG00000119048.3524.21950808.18880-0.624507.739706.41190K562EIF3G
UBE2BENSG00000119048.3968.65030673.658300.523904.943303.78780K562FIP1L1
UBE2BENSG00000119048.31388.12730975.077400.509502.223101.59970K562G3BP2
UBE2BENSG00000119048.3916.57560629.528600.541905.325104.52250K562HNRNPC
UBE2BENSG00000119048.31296.12040913.260900.505003.403702.52180K562HSPD1
UBE2BENSG00000119048.31819.743301287.562700.499006.092304.75960K562KIF1C
UBE2BENSG00000119048.31594.151401232.529700.371103.355802.13690K562MAK16
UBE2BENSG00000119048.31441.343701011.018300.511503.534802.51040K562NAA15
UBE2BENSG00000119048.3739.27940568.953700.377702.245701.56590K562PRPF8
UBE2BENSG00000119048.3779.643001189.05140-0.608908.049206.95830K562PTBP1
UBE2BENSG00000119048.32390.256501551.617000.623309.068807.57920K562PUF60
UBE2BENSG00000119048.32587.156401650.381700.648504.181302.85070K562PUM1
UBE2BENSG00000119048.32022.134601203.191400.7489010.689609.67010K562PUS1
UBE2BENSG00000119048.31428.61460930.278200.618803.659201.98830K562RAVER1
UBE2BENSG00000119048.31460.213901172.360700.316703.278002.64110K562RBM15
UBE2BENSG00000119048.3377.96140514.96730-0.446202.920101.90040K562RCC2
UBE2BENSG00000119048.3894.321801199.95640-0.424103.437302.19980K562NELFE
UBE2BENSG00000119048.3558.95620756.64110-0.436902.592001.62500K562RPS3
UBE2BENSG00000119048.3831.22050581.702300.514902.950401.57750K562RRP9
UBE2BENSG00000119048.3908.129601179.76590-0.377502.811402.09910K562TARDBP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for UBE2B is not available on ENCORE database.





29 RBPs can affect the splicing of UBE2B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUBE2BENSG00000119048.3chr5+1337240151337241041337100731337101541337259151337276830.075000.000080.00259includedK562SRSF1
SEUBE2BENSG00000119048.3chr5+133712281133712385133710073133710154133716409133716499-0.080000.002220.03947excludedK562SF3B4
SEUBE2BENSG00000119048.3chr5+1337240151337241041337100731337101541337259151337276830.076000.000100.02058includedK562MATR3
SEUBE2BENSG00000119048.3chr5+133724015133724104133710073133710154133725915133727683-0.160000.000000.00000excludedK562AKAP8L
SEUBE2BENSG00000119048.3chr5+1337246671337247431337240151337241041337259151337260120.186000.000000.00000includedK562XRCC6
SEUBE2BENSG00000119048.3chr5+133712359133712385133709998133710154133716409133716499-0.169000.000000.00000excludedK562AQR
SEUBE2BENSG00000119048.3chr5+1337240151337241041337100731337101541337259151337276830.055000.000320.01569includedK562FXR1
SEUBE2BENSG00000119048.3chr5+133724015133724104133710073133710154133725915133725989-0.228000.000000.00000excludedK562PUS1
SEUBE2BENSG00000119048.3chr5+1337240151337241041337100731337101541337259151337276830.065000.000330.09821includedK562KHSRP
SEUBE2BENSG00000119048.3chr5+133724015133724104133710073133710154133725915133725989-0.075000.000770.01818excludedK562U2AF1
SEUBE2BENSG00000119048.3chr5+133724015133724104133710073133710154133725915133725989-0.117000.000000.00000excludedK562UTP18
SEUBE2BENSG00000119048.3chr5+1337240151337241041337100731337101541337259151337276830.073000.000230.01202includedK562TARDBP
SEUBE2BENSG00000119048.3chr5+133724015133724104133710073133710154133725915133725989-0.148000.000000.00000excludedK562RBM15
SEUBE2BENSG00000119048.3chr5+133724015133724104133710073133710154133725915133725989-0.142000.000000.00000excludedK562AGGF1
SEUBE2BENSG00000119048.3chr5+1337240151337241041337100731337101541337259151337259890.078000.000020.00184includedK562HNRNPK
SEUBE2BENSG00000119048.3chr5+1337246671337247431337240151337241041337259151337260120.059000.000000.00013includedHepG2HNRNPC
SEUBE2BENSG00000119048.3chr5+1337240151337241041337100731337101541337259151337276830.078000.000500.02344includedK562PTBP1
SEUBE2BENSG00000119048.3chr5+133724015133724104133710073133710154133725915133725989-0.055000.000130.03273excludedK562NPM1
SEUBE2BENSG00000119048.3chr5+1337246671337247431337240151337241041337259151337260120.576000.000000.00000includedK562HNRNPC
A3SSUBE2BENSG00000119048.3chr5+1337123411337123851337123591337123851337099981337101540.184000.000000.00000longerK562AQR
MXEUBE2BENSG00000119048.3chr5+1337123591337123851337164091337164991337100731337101541337240151337241040.133000.000110.003581includedK562DROSHA
MXEUBE2BENSG00000119048.3chr5+1337123411337123851337163341337164991337099981337101541337240151337241040.210000.000000.000001includedK562AQR
MXEUBE2BENSG00000119048.3chr5+133712359133712385133716334133716499133709998133710154133724015133724104-0.084000.009480.060662includedK562AQR
MXEUBE2BENSG00000119048.3chr5+133712359133712385133716409133716499133710073133710154133724015133724104-0.123000.000190.002132includedK562AQR
MXEUBE2BENSG00000119048.3chr5+133710073133710154133724015133724104133706869133707330133725915133727683-0.079000.006610.068382includedK562U2AF2
MXEUBE2BENSG00000119048.3chr5+133716409133716499133724015133724104133712359133712385133725915133727683-0.102000.000050.005232includedHepG2BCCIP
MXEUBE2BENSG00000119048.3chr5+133712359133712385133716409133716499133710073133710154133724015133724104-0.163000.000010.000972includedHepG2XRN2
MXEUBE2BENSG00000119048.3chr5+133712359133712385133716409133716499133710073133710154133724015133724104-0.141000.000090.003582includedHepG2DDX55
MXEUBE2BENSG00000119048.3chr5+133712359133712385133716409133716499133710073133710154133724015133724104-0.118000.000510.082802includedK562PUM2
MXEUBE2BENSG00000119048.3chr5+133712359133712385133716409133716499133710073133710154133724015133724104-0.120000.000240.028642includedK562PUM1
MXEUBE2BENSG00000119048.3chr5+1337164091337164991337240151337241041337123591337123851337259151337276830.129000.000000.000251includedK562HNRNPC
MXEUBE2BENSG00000119048.3chr5+133716409133716499133724015133724104133712359133712385133725915133727683-0.077000.002980.081592includedHepG2SUPV3L1
MXEUBE2BENSG00000119048.3chr5+133716409133716499133724015133724104133712359133712385133725915133727683-0.096000.000280.032552includedHepG2ILF3
MXEUBE2BENSG00000119048.3chr5+133716409133716499133724015133724104133712359133712385133725915133727683-0.070000.002690.061412includedHepG2TIAL1
MXEUBE2BENSG00000119048.3chr5+1337123591337123851337164091337164991337100731337101541337240151337241040.160000.000120.024611includedK562NPM1
MXEUBE2BENSG00000119048.3chr5+1337123591337123851337164091337164991337100731337101541337240151337241040.110000.001680.033521includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for UBE2B is not avaliable on ENCORE database.