CLIC2

General Information

Gene Name       : CLIC2
Gene ID             : ENSG00000155962.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CLIC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CLIC2ENSG00000155962.1227.6424.2025.92ENCSR000AEF
HepG2CLIC2ENSG00000155962.120.160.120.14ENCSR985KAT
K562CLIC2ENSG00000155962.1244.9756.3350.65ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CLIC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CLIC2 RNA is bound by 12 proteins.  







eCLIP assay for CLIC2 is not avaliable on ENCORE database.





12 proteins are bound to CLIC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX154506923154506986-3'-UTR,intron-Distal3.627114.48983K562TIA1
chrX154507143154507175-3'-UTR,intron-Distal,intron-Proximal3.844996.76307K562LIN28B
chrX154506804154506849-3'-UTR,intron-Distal3.257618.67981K562YBX3
chrX154506995154507049-3'-UTR,intron-Distal3.988337.73013K562IGF2BP1
chrX154507060154507148-3'-UTR,intron-Distal3.447457.72939K562PABPC4
chrX154506938154506995-3'-UTR,intron-Distal4.1861110.14641K562IGF2BP1
chrX154563858154563927-5'-UTR,intron-Distal,intron-Proximal4.109958.04211K562DDX3X
chrX154509335154509353-CDS,intron-Distal4.3423314.35991K562YBX3
chrX154508470154508519-CDS,intron-Distal,intron-Proximal4.440974.42935K562SND1
chrX154507257154507346-CDS,intron-Distal,intron-Proximal3.009723.99218K562SND1
chrX154508469154508509-CDS,intron-Distal,intron-Proximal6.253988.90838K562RPS3
chrX154509353154509357-CDS,intron-Distal4.7747713.92894K562YBX3
chrX154508453154508507-CDS,intron-Distal,intron-Proximal3.747809.34382K562YBX3
chrX154528097154528141-CDS,intron-Distal,intron-Proximal5.3334220.52075K562YBX3
chrX154547000154547054-intron-Distal3.569964.57394K562HNRNPM
chrX154523914154523958-intron-Distal3.706984.61282K562EXOSC5
chrX154523119154523151-intron-Distal4.775055.12361K562EXOSC5
chrX154544327154544366-intron-Distal5.4287910.34146K562EXOSC5
chrX154545750154545850-intron-Distal5.141878.36828K562EXOSC5
chrX154547696154547777-intron-Distal5.9360113.98859K562EXOSC5
chrX154546563154546592-intron-Distal4.208503.59909K562EXOSC5
chrX154549824154549892-intron-Distal4.241943.29197K562HNRNPM
chrX154543838154543907-intron-Distal4.875507.06134K562EXOSC5
chrX154543554154543588-intron-Distal4.507023.89080K562EXOSC5
chrX154546995154547063-intron-Distal4.332787.61413K562EXOSC5
chrX154543588154543606-intron-Distal4.288733.59909K562EXOSC5
chrX154524048154524127-intron-Distal4.860936.08953K562EXOSC5
chrX154552488154552589-intron-Distal4.629456.36768K562HNRNPM
chrX154563572154563676-intron-Distal4.204433.49003K562PRPF8
chrX154543822154543917-intron-Distal3.734185.54542K562HNRNPM
chrX154548023154548067-intron-Distal4.749736.08953K562EXOSC5
chrX154546673154546703-intron-Distal4.304824.48560K562EXOSC5
chrX154544507154544554-intron-Distal4.389794.80466K562EXOSC5
chrX154552347154552389-intron-Distal4.825735.76606K562EXOSC5
chrX154552091154552133-intron-Distal4.509025.44433K562EXOSC5
chrX154553564154553615-intron-Distal5.115638.03988K562EXOSC5
chrX154546815154546856-intron-Distal5.254017.71312K562EXOSC5
chrX154523314154523413-intron-Distal3.430233.48890K562KHSRP
chrX154546448154546485-intron-Distal4.500984.80399K562EXOSC5
chrX154552491154552543-intron-Distal6.5406622.68925K562EXOSC5
chrX154543740154543787-intron-Distal4.138543.01445K562EXOSC5
chrX154523498154523537-intron-Distal3.304823.72904K562EXOSC5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CLIC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CLIC2 is not available on ENCORE database.

  • 55 RBPs can affect the levels of CLIC2.  








The Knockdown/knockout RNA-Seq assay for CLIC2 is not available on ENCORE database.





55 RBPs can affect the gene expression of CLIC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CLIC2ENSG00000155962.825.792000.868304.892406.214105.35900HepG2BOP1
CLIC2ENSG00000155962.821.989906.251601.814402.014201.42160HepG2DKC1
CLIC2ENSG00000155962.831.282508.026501.962403.001302.33540HepG2EIF4A3
CLIC2ENSG00000155962.810.315800.902203.515101.843501.31340HepG2GPKOW
CLIC2ENSG00000155962.815.364500.880404.125202.758101.79250HepG2MTPAP
CLIC2ENSG00000155962.821.822006.515901.743701.906601.39860HepG2PUF60
CLIC2ENSG00000155962.827.659607.093901.963002.599602.09330HepG2RBM22
CLIC2ENSG00000155962.833.187206.957202.254004.153003.55180HepG2SSB
CLIC2ENSG00000155962.812.784300.842003.924402.651601.93960HepG2TARDBP
CLIC2ENSG00000155962.815.850302.030502.964502.669102.17630HepG2TIAL1
CLIC2ENSG00000155962.83022.786802549.241100.245702.010401.45170K562AKAP8L
CLIC2ENSG00000155962.82121.784001356.217900.645607.908806.40280K562BOP1
CLIC2ENSG00000155962.81780.873602228.21820-0.323304.269302.87320K562CPEB4
CLIC2ENSG00000155962.81743.285501379.695300.337404.521902.81780K562DDX27
CLIC2ENSG00000155962.83098.028002305.648400.426108.758807.68070K562DDX47
CLIC2ENSG00000155962.81788.128501278.391500.484003.660002.16030K562EEF2
CLIC2ENSG00000155962.81156.521701934.83560-0.7424011.5609010.24040K562EIF2S2
CLIC2ENSG00000155962.81785.043101322.525900.432603.111602.01160K562EIF3D
CLIC2ENSG00000155962.82782.898803251.22140-0.224402.375901.50200K562EIF4G2
CLIC2ENSG00000155962.81251.920601611.60210-0.364403.288701.89170K562EXOSC5
CLIC2ENSG00000155962.82569.215901721.252900.577807.781206.28680K562FIP1L1
CLIC2ENSG00000155962.81311.511701594.39960-0.281802.835802.22450K562FXR1
CLIC2ENSG00000155962.82853.576401766.872200.691506.472005.28880K562G3BP2
CLIC2ENSG00000155962.81539.424802083.68180-0.436705.060103.58270K562HNRNPL
CLIC2ENSG00000155962.8790.187001415.83740-0.841409.894807.90040K562HNRNPM
CLIC2ENSG00000155962.81552.523902216.12760-0.513402.964501.89220K562IGF2BP2
CLIC2ENSG00000155962.83337.426402705.339900.302802.851902.01220K562KIF1C
CLIC2ENSG00000155962.81600.719001175.631100.445202.832301.88560K562KRR1
CLIC2ENSG00000155962.81171.108702325.85210-0.989908.780607.03970K562MATR3
CLIC2ENSG00000155962.84234.662703465.489100.289102.461701.39770K562MSI2
CLIC2ENSG00000155962.81038.762201578.47290-0.6037012.8101011.22350K562MTPAP
CLIC2ENSG00000155962.81002.681401409.79060-0.491603.741701.98180K562NUSAP1
CLIC2ENSG00000155962.82647.014202049.956000.368702.794201.95850K562PCBP3
CLIC2ENSG00000155962.82613.802203340.72600-0.354003.586301.95790K562PNPT1
CLIC2ENSG00000155962.82012.307801572.432800.355803.985303.01790K562POLR2G
CLIC2ENSG00000155962.81750.822101201.978100.542505.731904.65050K562PRPF8
CLIC2ENSG00000155962.8699.765001283.88050-0.8756012.8660010.62610K562PSIP1
CLIC2ENSG00000155962.81734.503702264.01130-0.384402.335401.71850K562PTBP1
CLIC2ENSG00000155962.82627.901601685.808800.640404.082802.30150K562RAVER1
CLIC2ENSG00000155962.82884.049302463.286600.227402.424101.86270K562RBM15
CLIC2ENSG00000155962.81400.604302171.63570-0.632703.937602.92060K562RBM22
CLIC2ENSG00000155962.81845.469001224.361200.591905.084803.97440K562RPS19
CLIC2ENSG00000155962.82195.694001228.984900.837108.658906.37980K562RRP9
CLIC2ENSG00000155962.82040.297801448.463400.494205.397003.36790K562SDAD1
CLIC2ENSG00000155962.81503.527101837.23380-0.289202.747101.89570K562SF3B4
CLIC2ENSG00000155962.8860.541401110.35170-0.367702.789701.76040K562SRFBP1
CLIC2ENSG00000155962.82192.736601772.968700.306505.004603.79070K562SRPK2
CLIC2ENSG00000155962.81523.705702219.33810-0.542503.914603.07930K562SRSF1
CLIC2ENSG00000155962.81353.539901668.49880-0.301802.511101.51610K562SRSF4
CLIC2ENSG00000155962.82269.993301789.863700.342703.789001.99650K562SRSF9
CLIC2ENSG00000155962.81843.298301463.538600.332703.255901.84630K562SSB
CLIC2ENSG00000155962.83605.444002136.721700.754703.338501.72040K562SUPT6H
CLIC2ENSG00000155962.81733.454001163.794700.574703.579402.40790K562SUPV3L1
CLIC2ENSG00000155962.81317.536801577.12660-0.259502.102801.38590K562SYNCRIP
CLIC2ENSG00000155962.81525.374902246.43340-0.558503.609102.79780K562TARDBP
CLIC2ENSG00000155962.81653.133802166.85500-0.390402.359001.61020K562TIA1
CLIC2ENSG00000155962.8829.656701234.88980-0.573805.194603.86970K562TIAL1
CLIC2ENSG00000155962.82201.561001768.816800.315603.324002.44540K562U2AF2
CLIC2ENSG00000155962.82117.908101231.723300.7819011.126009.03780K562UCHL5
CLIC2ENSG00000155962.81903.464701591.284700.258302.084601.32680K562WDR3
CLIC2ENSG00000155962.82342.531801654.688900.501403.885002.89350K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CLIC2 is not available on ENCORE database.





6 RBPs can affect the splicing of CLIC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECLIC2ENSG00000155962.8chrX-154528348154528458154509250154509357154563679154563955-0.085000.004720.07082excludedK562SF3B4
SECLIC2ENSG00000155962.8chrX-1545080991545082191545072681545073531545084371545086190.106000.000000.00000includedK562XRCC6
SECLIC2ENSG00000155962.8chrX-154528348154528458154509250154509357154563679154563955-0.070000.000000.00004excludedK562AQR
SECLIC2ENSG00000155962.8chrX-154528348154528458154509250154509357154563679154563955-0.279000.000010.00436excludedK562HNRNPM
SECLIC2ENSG00000155962.8chrX-1545283481545284581545092501545093571545636791545639550.143000.001110.09565includedK562CPSF6
SECLIC2ENSG00000155962.8chrX-1545080991545082191545072681545073531545084371545086190.090000.000000.00000includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CLIC2 is not avaliable on ENCORE database.