SPEN

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SPEN	ENSG00000065526.10	28.42	39.93	34.17	ENCSR000AEF
HepG2	SPEN	ENSG00000065526.10	24.89	19.72	22.30	ENCSR985KAT
K562	SPEN	ENSG00000065526.10	63.29	58.82	61.05	ENCSR000AEO

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SPEN is not avaliable on ENCORE database.

Proteins bound to RNA

SPEN RNA is bound by 61 proteins.

eCLIP assay for SPEN is not avaliable on ENCORE database.

61 proteins are bound to SPEN RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	16265916	16265932	+	3'-UTR,CDS	3.53864	4.22460	K562	RBM15
chr1	16266300	16266337	+	3'-UTR	4.11321	7.45227	K562	RBM15
chr1	16266726	16266859	+	3'-UTR	3.60358	12.69332	K562	PUM2
chr1	16266814	16266861	+	3'-UTR	5.15418	3.92758	K562	PCBP1
chr1	16265877	16265922	+	3'-UTR,CDS	3.13904	3.17744	HepG2	GRWD1
chr1	16266478	16266529	+	3'-UTR	5.61552	13.21799	K562	PUM2
chr1	16266816	16266869	+	3'-UTR	5.04025	13.92665	HepG2	PCBP2
chr1	16266818	16266922	+	3'-UTR	4.13191	9.36317	K562	QKI
chr1	16266553	16266593	+	3'-UTR	6.90925	11.75835	K562	PUM2
chr1	16174371	16174472	+	5'-UTR	5.00134	6.95882	HepG2	GRSF1
chr1	16174405	16174462	+	5'-UTR	3.52153	14.66882	K562	UCHL5
chr1	16174506	16174592	+	5'-UTR,CDS	3.32766	6.67587	HepG2	DDX3X
chr1	16174395	16174488	+	5'-UTR	3.74052	22.55100	K562	GEMIN5
chr1	16174388	16174467	+	5'-UTR	3.19092	13.23712	K562	ZNF622
chr1	16174383	16174472	+	5'-UTR	3.79098	6.91244	HepG2	NCBP2
chr1	16174504	16174585	+	5'-UTR,CDS	4.49148	8.71519	K562	GEMIN5
chr1	16200213	16200289	+	5'-UTR,intron-Distal	3.82562	17.24564	K562	RBM15
chr1	16174387	16174487	+	5'-UTR	3.27652	9.98084	HepG2	EIF3H
chr1	16200340	16200374	+	5'-UTR,intron-Distal	5.37847	10.03208	K562	RBM15
chr1	16174387	16174493	+	5'-UTR	3.57377	15.86643	K562	DDX6
chr1	16174377	16174500	+	5'-UTR	3.04745	8.45635	K562	FUS
chr1	16200005	16200059	+	5'-UTR,intron-Distal	3.69255	6.92356	K562	NIPBL
chr1	16174523	16174569	+	5'-UTR,CDS	5.25266	4.97000	K562	DDX3X
chr1	16174391	16174475	+	5'-UTR	3.45339	8.15779	K562	ZNF800
chr1	16174370	16174458	+	5'-UTR	4.60766	15.02705	K562	PUM1
chr1	16174389	16174467	+	5'-UTR	3.26858	16.55149	K562	DROSHA
chr1	16200010	16200080	+	5'-UTR,intron-Distal	5.20603	24.12770	K562	RBM15
chr1	16200335	16200368	+	5'-UTR,intron-Distal	4.91128	13.28384	K562	UCHL5
chr1	16174389	16174471	+	5'-UTR	3.18127	13.44649	HepG2	DDX3X
chr1	16200333	16200389	+	5'-UTR,intron-Distal	3.02465	3.09975	K562	FTO
chr1	16200808	16200891	+	CDS,intron-Distal,intron-Proximal	4.31851	11.65401	K562	UPF1
chr1	16259810	16259857	+	CDS	5.60152	8.03056	HepG2	FXR2
chr1	16255218	16255294	+	CDS	3.25237	7.33351	K562	SAFB2
chr1	16263974	16264067	+	CDS	4.75050	10.60875	K562	PCBP1
chr1	16257785	16257819	+	CDS	3.44836	7.17953	K562	RBM15
chr1	16257833	16257880	+	CDS	3.37293	11.37435	K562	UCHL5
chr1	16262492	16262580	+	CDS	5.48510	5.87144	HepG2	PCBP1
chr1	16260494	16260551	+	CDS	3.71339	6.21348	K562	YBX3
chr1	16255216	16255249	+	CDS	3.74481	3.22063	K562	TRA2A
chr1	16256975	16256999	+	CDS	3.67260	11.23706	K562	UCHL5
chr1	16248769	16248798	+	CDS	4.42850	5.79396	K562	DDX24
chr1	16245898	16245942	+	CDS,intron-Proximal	3.91450	7.34123	K562	DDX24
chr1	16255631	16255695	+	CDS	3.84779	10.27045	K562	SLTM
chr1	16199345	16199402	+	CDS	3.40457	14.72846	K562	UCHL5
chr1	16255317	16255499	+	CDS	4.17062	38.21444	K562	UCHL5
chr1	16257326	16257375	+	CDS	3.50138	11.11590	K562	RBM15
chr1	16259044	16259108	+	CDS	4.07616	8.97056	K562	FXR2
chr1	16260611	16260629	+	CDS	4.59980	8.58706	K562	UCHL5
chr1	16255576	16255605	+	CDS	3.13199	3.73364	K562	SAFB2
chr1	16255808	16255854	+	CDS	3.58100	9.12920	K562	UCHL5
chr1	16261724	16261773	+	CDS	3.23268	5.09613	K562	IGF2BP2
chr1	16264076	16264136	+	CDS	3.86057	6.76074	K562	IGF2BP2
chr1	16247350	16247414	+	CDS,intron-Proximal	5.06982	7.27507	HepG2	U2AF2
chr1	16259619	16259645	+	CDS	4.03262	5.37287	K562	SLTM
chr1	16258745	16258789	+	CDS	4.26001	3.82973	HepG2	HLTF
chr1	16259038	16259103	+	CDS	3.63027	5.08339	K562	TRA2A
chr1	16254814	16254918	+	CDS	4.03239	32.40390	K562	UCHL5
chr1	16242749	16242768	+	CDS	3.19746	5.39278	K562	ZNF622
chr1	16199533	16199559	+	CDS	5.36144	14.88923	K562	RBM15
chr1	16258621	16258742	+	CDS	3.58411	13.65687	HepG2	FXR2
chr1	16258752	16258807	+	CDS	3.90047	6.16300	K562	FMR1
chr1	16199530	16199565	+	CDS	3.94503	11.94097	K562	UCHL5
chr1	16237760	16237890	+	CDS,intron-Proximal	3.84198	14.14355	K562	PRPF8
chr1	16262699	16262760	+	CDS	4.36377	5.09622	HepG2	IGF2BP1
chr1	16256347	16256397	+	CDS	3.62551	9.89786	K562	RBM15
chr1	16255202	16255317	+	CDS	4.44972	29.03261	K562	UCHL5
chr1	16254969	16255025	+	CDS	4.99054	6.32937	K562	LIN28B
chr1	16174562	16174610	+	CDS	3.11582	3.45165	K562	FXR2
chr1	16257602	16257677	+	CDS	3.75254	5.84448	K562	YWHAG
chr1	16262481	16262579	+	CDS	4.80794	20.23797	HepG2	DDX59
chr1	16237763	16237843	+	CDS,intron-Proximal	5.00646	10.42975	HepG2	PRPF8
chr1	16258014	16258079	+	CDS	3.12715	8.29055	K562	RBM15
chr1	16260678	16260702	+	CDS	4.84513	6.57313	K562	RBM15
chr1	16258615	16258675	+	CDS	3.64916	7.17964	K562	ZNF800
chr1	16255646	16255721	+	CDS	4.50826	26.56618	K562	UCHL5
chr1	16257937	16258060	+	CDS	4.05824	6.18214	HepG2	GRWD1
chr1	16256488	16256538	+	CDS	3.50456	4.39680	K562	YWHAG
chr1	16237740	16237807	+	CDS,intron-Proximal	3.32704	3.62863	K562	SRSF1
chr1	16258422	16258441	+	CDS	5.18087	6.28417	HepG2	FXR2
chr1	16259383	16259453	+	CDS	4.58063	10.22357	K562	FXR2
chr1	16259150	16259209	+	CDS	4.55410	9.14010	HepG2	BCLAF1
chr1	16257741	16257814	+	CDS	3.88924	7.03378	HepG2	GRWD1
chr1	16264138	16264184	+	CDS,intron-Proximal	3.59227	9.09021	HepG2	PRPF8
chr1	16257750	16257832	+	CDS	3.86820	18.91140	K562	UCHL5
chr1	16256346	16256404	+	CDS	4.31035	8.56425	K562	FXR2
chr1	16262616	16262644	+	CDS	5.18267	7.58445	K562	RBM15
chr1	16254664	16254710	+	CDS	4.04866	3.48757	K562	TRA2A
chr1	16261718	16261778	+	CDS	4.06718	8.36163	HepG2	IGF2BP1
chr1	16258745	16258793	+	CDS	3.76494	9.25079	K562	ZNF622
chr1	16258688	16258717	+	CDS	5.01306	12.91898	K562	UCHL5
chr1	16237598	16237617	+	CDS	3.56261	4.77019	K562	BUD13
chr1	16260029	16260052	+	CDS	3.39206	4.98411	K562	RBM15
chr1	16262547	16262592	+	CDS	6.11210	8.19722	HepG2	PCBP2
chr1	16255418	16255486	+	CDS	3.26082	6.06438	HepG2	BCLAF1
chr1	16258701	16258818	+	CDS	3.33787	10.88713	K562	SLTM
chr1	16245424	16245547	+	CDS,intron-Proximal	3.04325	10.63537	K562	UPF1
chr1	16254933	16254970	+	CDS	3.74014	6.73435	K562	SLTM
chr1	16259106	16259196	+	CDS	3.60187	7.56697	K562	METAP2
chr1	16255349	16255425	+	CDS	3.62580	7.72583	K562	GRWD1
chr1	16260590	16260646	+	CDS	3.30722	4.19285	K562	IGF2BP1
chr1	16247353	16247416	+	CDS,intron-Proximal	4.58347	7.19069	K562	U2AF2
chr1	16200787	16200817	+	CDS,intron-Distal	5.67131	11.79327	K562	RBM15
chr1	16255581	16255646	+	CDS	4.57080	20.41928	K562	UCHL5
chr1	16259084	16259168	+	CDS	4.35224	15.49974	K562	UCHL5
chr1	16257325	16257334	+	CDS	3.41192	4.74241	K562	YBX3
chr1	16199369	16199431	+	CDS	4.41901	16.35865	K562	RBM15
chr1	16255462	16255498	+	CDS	4.38269	3.83566	K562	YWHAG
chr1	16257238	16257287	+	CDS	3.39663	8.43531	K562	ZNF622
chr1	16258364	16258465	+	CDS	5.49045	26.53259	K562	UCHL5
chr1	16264484	16264550	+	CDS,intron-Proximal	3.14388	3.94654	HepG2	PRPF8
chr1	16256034	16256117	+	CDS	4.51487	11.82623	HepG2	FXR2
chr1	16259423	16259453	+	CDS	4.84183	5.85077	HepG2	FXR2
chr1	16245898	16245942	+	CDS,intron-Proximal	3.49134	7.01246	HepG2	BCLAF1
chr1	16256953	16256975	+	CDS	3.44842	11.00019	K562	UCHL5
chr1	16259111	16259251	+	CDS	3.83651	11.10802	HepG2	FXR2
chr1	16256509	16256548	+	CDS	4.06523	9.79481	K562	UCHL5
chr1	16264500	16264558	+	CDS,intron-Proximal	5.19963	5.65342	K562	AQR
chr1	16256128	16256170	+	CDS	3.84546	9.96940	K562	UCHL5
chr1	16257924	16258000	+	CDS	3.03289	10.63982	K562	RBM15
chr1	16237772	16237793	+	CDS	3.08034	3.71797	HepG2	BCLAF1
chr1	16255368	16255405	+	CDS	3.24140	6.73967	K562	ZNF622
chr1	16257205	16257278	+	CDS	4.50099	11.55000	HepG2	BCLAF1
chr1	16256548	16256573	+	CDS	4.84436	5.70640	HepG2	BCLAF1
chr1	16263705	16263784	+	CDS	3.59083	5.37198	HepG2	IGF2BP1
chr1	16264138	16264156	+	CDS,intron-Proximal	6.25180	16.44435	K562	AQR
chr1	16257998	16258041	+	CDS	4.81238	8.85442	HepG2	FXR2
chr1	16261700	16261786	+	CDS	3.30091	7.82337	K562	IGF2BP1
chr1	16257563	16257618	+	CDS	5.43059	10.96850	K562	RBM15
chr1	16254584	16254628	+	CDS,intron-Proximal	3.97372	14.88813	K562	UCHL5
chr1	16202696	16202773	+	CDS,intron-Proximal	3.87866	9.37566	K562	UPF1
chr1	16245907	16245938	+	CDS	3.77942	3.65778	K562	GRWD1
chr1	16254855	16254908	+	CDS	3.95235	13.44258	K562	RBM15
chr1	16254834	16254917	+	CDS	3.45119	7.20537	K562	TRA2A
chr1	16245440	16245544	+	CDS	4.13251	15.37934	HepG2	BCLAF1
chr1	16257222	16257273	+	CDS	3.13236	5.49645	K562	GRWD1
chr1	16259040	16259055	+	CDS	4.13369	4.95232	K562	XRCC6
chr1	16256947	16257004	+	CDS	4.82479	13.15731	K562	RBM15
chr1	16237760	16237777	+	CDS	3.53979	4.51666	K562	RBM15
chr1	16257593	16257628	+	CDS	4.47765	5.08354	K562	TRA2A
chr1	16257814	16257937	+	CDS	5.12726	8.32768	HepG2	GRWD1
chr1	16261495	16261518	+	CDS	3.24736	5.58482	K562	YBX3
chr1	16258736	16258794	+	CDS	4.16991	11.79915	K562	UCHL5
chr1	16246010	16246018	+	CDS,intron-Proximal	3.90865	4.88100	K562	AQR
chr1	16257592	16257674	+	CDS	4.48238	11.99763	HepG2	BCLAF1
chr1	16255721	16255780	+	CDS	3.91649	12.75382	K562	UCHL5
chr1	16257578	16257678	+	CDS	4.27753	28.40246	K562	UCHL5
chr1	16245991	16246062	+	CDS,intron-Proximal	3.47274	4.50321	HepG2	PRPF8
chr1	16257753	16257858	+	CDS	3.44195	8.11718	K562	TRA2A
chr1	16263908	16264000	+	CDS	4.11666	7.60928	HepG2	PCBP2
chr1	16262472	16262559	+	CDS	4.91423	19.03355	HepG2	HNRNPK
chr1	16254843	16254908	+	CDS	5.15230	13.34895	HepG2	BCLAF1
chr1	16262476	16262549	+	CDS	3.21217	4.27525	HepG2	ILF3
chr1	16256284	16256335	+	CDS	3.66813	8.83000	K562	UCHL5
chr1	16259412	16259496	+	CDS	3.67805	3.55204	K562	FXR1
chr1	16254921	16254968	+	CDS	4.54606	10.71068	K562	RBM15
chr1	16256348	16256400	+	CDS	4.73894	5.26571	K562	FMR1
chr1	16256363	16256372	+	CDS	3.38176	5.51859	K562	SLTM
chr1	16257618	16257681	+	CDS	3.66625	11.03005	K562	RBM15
chr1	16257356	16257426	+	CDS	3.28443	4.36388	HepG2	EIF3H
chr1	16264277	16264326	+	CDS,intron-Proximal	3.87645	6.79537	K562	AQR
chr1	16259168	16259232	+	CDS	4.05111	23.79934	K562	UCHL5
chr1	16262472	16262547	+	CDS	7.08438	52.23130	HepG2	PCBP2
chr1	16257397	16257464	+	CDS	3.66949	14.94623	HepG2	BCLAF1
chr1	16262499	16262529	+	CDS	4.01947	7.03491	K562	RBM15
chr1	16263721	16263778	+	CDS	3.69509	4.78882	K562	IGF2BP2
chr1	16256349	16256369	+	CDS	4.25506	4.68575	HepG2	FXR2
chr1	16258435	16258472	+	CDS	3.89420	6.43014	K562	SLTM
chr1	16261885	16261926	+	CDS	3.58188	4.94406	K562	YBX3
chr1	16262760	16262803	+	CDS,intron-Proximal	4.73863	12.46803	K562	AQR
chr1	16258366	16258436	+	CDS	3.76347	5.74979	HepG2	GRWD1
chr1	16257392	16257462	+	CDS	3.26783	6.63825	HepG2	GRWD1
chr1	16258760	16258831	+	CDS	4.85611	8.85442	HepG2	FXR2
chr1	16257038	16257079	+	CDS	4.36728	9.38865	K562	RBM15
chr1	16257394	16257460	+	CDS	4.47513	10.14604	HepG2	FXR2
chr1	16256675	16256709	+	CDS	4.02425	12.90299	K562	UCHL5
chr1	16263629	16263683	+	CDS,intron-Proximal	3.91313	6.42898	K562	AQR
chr1	16262483	16262537	+	CDS	6.23257	11.10821	K562	PCBP1
chr1	16257401	16257441	+	CDS	3.38944	4.73359	K562	PUM1
chr1	16200737	16200787	+	CDS,intron-Distal	4.50326	16.28134	K562	RBM15
chr1	16262481	16262547	+	CDS	4.38752	18.13440	K562	HNRNPK
chr1	16259032	16259136	+	CDS	4.03051	18.82670	K562	SLTM
chr1	16257934	16257969	+	CDS	4.18398	14.65767	K562	UCHL5
chr1	16258706	16258788	+	CDS	3.17309	5.23342	HepG2	G3BP1
chr1	16254924	16254962	+	CDS	3.94493	16.43895	K562	UCHL5
chr1	16259255	16259296	+	CDS	5.43706	21.65749	K562	UCHL5
chr1	16262504	16262550	+	CDS	3.56833	4.10184	HepG2	FXR2
chr1	16245900	16245940	+	CDS	3.13639	10.85799	K562	UCHL5
chr1	16257392	16257474	+	CDS	3.51485	17.53047	K562	RBM15
chr1	16256951	16256993	+	CDS	3.02019	5.27152	HepG2	BCLAF1
chr1	16262746	16262839	+	CDS,intron-Proximal	3.36617	5.83656	K562	PRPF8
chr1	16199559	16199633	+	CDS,intron-Proximal	6.00595	27.54500	K562	RBM15
chr1	16256548	16256605	+	CDS	5.39406	14.38113	K562	UCHL5
chr1	16259727	16259754	+	CDS	3.15839	5.10919	K562	SLTM
chr1	16255466	16255524	+	CDS	3.35791	7.63771	K562	RBM15
chr1	16254845	16254985	+	CDS	3.13588	5.39072	HepG2	GRWD1
chr1	16262485	16262644	+	CDS	3.33063	15.77350	K562	ILF3
chr1	16261041	16261090	+	CDS	3.44737	6.82132	K562	YBX3
chr1	16256849	16256881	+	CDS	3.48258	5.51859	K562	SLTM
chr1	16256097	16256162	+	CDS	4.55910	8.47938	HepG2	BCLAF1
chr1	16257252	16257289	+	CDS	3.95574	10.47889	K562	UCHL5
chr1	16257760	16257817	+	CDS	3.00456	4.21966	K562	YWHAG
chr1	16258343	16258375	+	CDS	3.27881	6.26015	K562	RBM15
chr1	16256841	16256891	+	CDS	3.42471	12.86621	K562	UCHL5
chr1	16258383	16258459	+	CDS	3.44025	7.41391	K562	RBM15
chr1	16254836	16254895	+	CDS	4.89288	8.42950	HepG2	FXR2
chr1	16245496	16245547	+	CDS,intron-Proximal	3.26337	7.98451	K562	DDX24
chr1	16259022	16259065	+	CDS	3.74040	5.89284	K562	RBM15
chr1	16257405	16257453	+	CDS	3.10758	5.81106	K562	NIPBL
chr1	16261971	16262095	+	CDS	3.97358	9.55443	HepG2	IGF2BP1
chr1	16248837	16248843	+	CDS	3.46741	7.55111	K562	UCHL5
chr1	16264447	16264493	+	CDS	3.32100	5.26861	K562	DDX24
chr1	16256317	16256407	+	CDS	3.32387	4.26316	K562	FXR1
chr1	16257760	16257917	+	CDS	3.59200	24.92768	K562	ZNF622
chr1	16254585	16254614	+	CDS,intron-Proximal	4.89735	3.29312	HepG2	FXR2
chr1	16255244	16255285	+	CDS	4.05410	6.23296	HepG2	BCLAF1
chr1	16259247	16259292	+	CDS	3.15767	5.22126	K562	YWHAG
chr1	16202716	16202769	+	CDS	3.35469	4.37145	K562	GRWD1
chr1	16261900	16261993	+	CDS	3.67453	7.82337	K562	IGF2BP1
chr1	16259603	16259640	+	CDS	4.52645	9.28061	HepG2	FXR2
chr1	16258748	16258807	+	CDS	5.43577	9.56947	K562	FXR2
chr1	16245529	16245544	+	CDS	4.57080	9.30180	K562	UCHL5
chr1	16257628	16257677	+	CDS	3.61330	5.08339	K562	TRA2A
chr1	16257389	16257454	+	CDS	3.57006	10.34700	K562	GRWD1
chr1	16256952	16256991	+	CDS	3.25400	5.22126	K562	YWHAG
chr1	16265160	16265250	+	CDS,intron-Proximal	6.03693	13.04469	K562	SF3B4
chr1	16259221	16259283	+	CDS	3.06049	9.60277	K562	SLTM
chr1	16259184	16259257	+	CDS	4.41772	12.87490	K562	FXR2
chr1	16248822	16248837	+	CDS	3.35496	10.40226	K562	UCHL5
chr1	16261639	16261724	+	CDS	3.37741	9.12996	K562	IGF2BP2
chr1	16255587	16255631	+	CDS	4.10518	8.54032	K562	SLTM
chr1	16257329	16257374	+	CDS	3.34659	5.07457	HepG2	BCLAF1
chr1	16245527	16245546	+	CDS	3.89439	6.60685	K562	BUD13
chr1	16257336	16257367	+	CDS	3.81003	3.12746	HepG2	GRWD1
chr1	16259472	16259524	+	CDS	3.95606	11.43233	K562	SLTM
chr1	16256000	16256089	+	CDS	3.71612	16.22911	K562	UCHL5
chr1	16258550	16258589	+	CDS	3.07659	5.09917	K562	SLTM
chr1	16262219	16262260	+	CDS	3.63404	5.37252	K562	YBX3
chr1	16258555	16258601	+	CDS	3.37633	3.69824	K562	TRA2A
chr1	16262700	16262762	+	CDS,intron-Proximal	3.12138	4.97172	K562	IGF2BP2
chr1	16200670	16200712	+	CDS,intron-Distal	6.60489	18.90022	K562	RBM15
chr1	16258217	16258267	+	CDS	3.60862	6.21345	K562	SLTM
chr1	16199465	16199496	+	CDS	5.06011	7.58445	K562	RBM15
chr1	16260436	16260474	+	CDS	3.08239	5.20141	K562	SLTM
chr1	16260272	16260338	+	CDS	3.06028	3.38325	HepG2	IGF2BP1
chr1	16257792	16257823	+	CDS	3.56230	4.92987	K562	MTPAP
chr1	16186841	16187007	+	intron-Distal	5.49847	22.54839	K562	EIF4G2
chr1	16174995	16175026	+	intron-Distal	3.81310	3.21586	K562	DDX52
chr1	16175555	16175647	+	intron-Distal	3.03333	3.87422	HepG2	CSTF2
chr1	16175175	16175217	+	intron-Distal	4.59973	6.16396	K562	NONO
chr1	16199898	16199977	+	intron-Distal	3.99357	11.82232	K562	DDX3X
chr1	16232382	16232504	+	intron-Distal	3.49474	6.59733	K562	KHSRP
chr1	16232504	16232619	+	intron-Distal	3.70730	5.32884	K562	KHSRP
chr1	16199922	16199979	+	intron-Distal	6.05340	16.04835	K562	RBM15
chr1	16175560	16175617	+	intron-Distal	3.34653	3.84340	K562	CSTF2T
chr1	16175927	16175982	+	intron-Distal	4.09558	3.80314	K562	CSTF2T
chr1	16242802	16242921	+	intron-Distal,intron-Proximal	3.29759	4.13620	K562	KHSRP
chr1	16176018	16176085	+	intron-Distal	4.66073	5.66217	K562	NONO
chr1	16248995	16249069	+	intron-Distal	3.19970	3.94281	K562	PRPF8
chr1	16219810	16219908	+	intron-Distal	4.85089	5.16513	HepG2	HNRNPM
chr1	16175051	16175149	+	intron-Distal	4.24325	7.48999	K562	NONO
chr1	16199798	16199852	+	intron-Distal	3.89519	4.29577	K562	FTO
chr1	16176119	16176191	+	intron-Distal	3.41198	5.20317	K562	NONO
chr1	16202523	16202660	+	intron-Distal,intron-Proximal	3.30311	7.42856	K562	KHSRP
chr1	16176040	16176110	+	intron-Distal	3.60565	3.35564	K562	FUS
chr1	16199734	16199830	+	intron-Distal	3.57010	19.34377	K562	UCHL5
chr1	16175264	16175347	+	intron-Distal	4.41054	9.37458	K562	NONO
chr1	16245595	16245729	+	intron-Distal,intron-Proximal	3.05268	5.42536	K562	KHSRP
chr1	16176123	16176165	+	intron-Distal	3.30057	3.50009	K562	CSTF2T
chr1	16199785	16199826	+	intron-Distal	4.86566	8.38377	K562	LIN28B
chr1	16174995	16175059	+	intron-Distal	3.24018	3.37264	K562	LSM11
chr1	16197056	16197177	+	intron-Distal	4.59841	4.66266	K562	TARDBP
chr1	16175159	16175211	+	intron-Distal	3.88130	3.70058	K562	CSTF2T
chr1	16200937	16201023	+	intron-Distal,intron-Proximal	5.51158	14.67956	K562	QKI
chr1	16175276	16175334	+	intron-Distal	4.48542	5.20806	K562	TIA1
chr1	16200941	16201047	+	intron-Distal,intron-Proximal	4.29324	12.02397	HepG2	QKI
chr1	16199735	16199790	+	intron-Distal	5.36874	17.67760	K562	RBM15
chr1	16203505	16203600	+	intron-Distal	3.29418	8.68012	K562	KHSRP
chr1	16175922	16175980	+	intron-Distal	4.19272	3.87357	K562	EWSR1
chr1	16174797	16174864	+	intron-Distal	4.39471	4.02737	K562	PHF6
chr1	16175917	16176007	+	intron-Distal	5.19108	16.54800	K562	NONO
chr1	16199726	16199794	+	intron-Distal,intron-Proximal	4.02120	8.47933	K562	XRCC6
chr1	16203233	16203364	+	intron-Distal,intron-Proximal	3.69656	12.80002	K562	KHSRP
chr1	16199816	16199847	+	intron-Distal	3.99247	5.38772	K562	RBM15
chr1	16174902	16175033	+	intron-Distal	3.17563	5.68177	HepG2	CSTF2T
chr1	16199865	16199878	+	intron-Distal	6.34906	17.82965	K562	RBM15
chr1	16175909	16175996	+	intron-Distal	4.61588	7.73600	K562	FUS
chr1	16199878	16199922	+	intron-Distal	6.92028	26.78079	K562	RBM15
chr1	16245618	16245661	+	intron-Distal,intron-Proximal	3.30843	3.20886	K562	PRPF8
chr1	16263502	16263593	+	intron-Distal,intron-Proximal	4.91183	3.85055	HepG2	XPO5
chr1	16248925	16248980	+	intron-Distal,intron-Proximal	4.56438	4.58968	K562	PRPF8
chr1	16219820	16219909	+	intron-Distal	3.54449	7.03773	K562	HNRNPM
chr1	16175904	16175969	+	intron-Distal	4.99439	4.99229	K562	DDX52
chr1	16199826	16199859	+	intron-Distal	4.58498	6.01926	K562	LIN28B
chr1	16199659	16199707	+	intron-Proximal	3.65272	6.40705	K562	XRCC6
chr1	16246018	16246084	+	intron-Proximal	4.65681	9.80019	K562	AQR
chr1	16199669	16199696	+	intron-Proximal	5.42323	10.38360	K562	RBM15
chr1	16237815	16237839	+	intron-Proximal	3.61638	6.69302	K562	AQR
chr1	16199696	16199712	+	intron-Proximal	5.14408	8.98006	K562	RBM15
chr1	16264156	16264184	+	intron-Proximal	6.26014	14.81397	K562	AQR
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for SPEN is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SPEN is not available on ENCORE database.
100 RBPs can affect the levels of SPEN.

The Knockdown/knockout RNA-Seq assay for SPEN is not available on ENCORE database.

100 RBPs can affect the gene expression of SPEN :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SPEN	ENSG00000065526.6	3249.71460	4082.94440	-0.32930	2.65140	1.72840	HepG2	ABCF1
SPEN	ENSG00000065526.6	2459.13000	2841.56380	-0.20850	2.81820	2.20580	HepG2	ACO1
SPEN	ENSG00000065526.6	1440.34030	2163.59670	-0.58700	5.26240	4.55770	HepG2	AKAP1
SPEN	ENSG00000065526.6	3332.32250	4411.40590	-0.40470	3.26340	2.13770	HepG2	AKAP8
SPEN	ENSG00000065526.6	2918.25220	3424.96620	-0.23100	3.06520	2.34810	HepG2	AUH
SPEN	ENSG00000065526.6	1331.42110	1880.51970	-0.49820	4.11510	2.97550	HepG2	BCCIP
SPEN	ENSG00000065526.6	2289.83930	2729.32300	-0.25330	2.30200	1.59310	HepG2	CALR
SPEN	ENSG00000065526.6	3414.29430	4442.29370	-0.37970	2.45140	1.54090	HepG2	CCAR1
SPEN	ENSG00000065526.6	1527.63420	2019.10000	-0.40240	4.87010	3.52140	HepG2	YBX3
SPEN	ENSG00000065526.6	2281.61330	2628.03420	-0.20390	2.73740	1.90730	HepG2	DDX19B
SPEN	ENSG00000065526.6	1563.61970	2021.89830	-0.37080	4.99330	3.47290	HepG2	DDX1
SPEN	ENSG00000065526.6	1233.36450	2058.28610	-0.73880	11.84400	10.55580	HepG2	DDX21
SPEN	ENSG00000065526.6	1364.30090	1848.98100	-0.43860	3.36570	2.52290	HepG2	DDX55
SPEN	ENSG00000065526.6	2168.67820	2718.60360	-0.32600	5.22540	4.34770	HepG2	DKC1
SPEN	ENSG00000065526.6	1715.20420	1982.57810	-0.20900	1.93390	1.33460	HepG2	DNAJC21
SPEN	ENSG00000065526.6	1588.94630	1965.11020	-0.30650	5.17660	4.32920	HepG2	DNAJC2
SPEN	ENSG00000065526.6	1842.34230	2505.52150	-0.44360	4.17630	3.06600	HepG2	EEF2
SPEN	ENSG00000065526.6	2394.76510	1711.43030	0.48460	4.46550	3.72220	HepG2	EIF2S1
SPEN	ENSG00000065526.6	1506.11030	1817.83860	-0.27140	2.46060	1.36000	HepG2	FAM120A
SPEN	ENSG00000065526.6	2327.87470	1413.21760	0.71990	8.34760	7.02030	HepG2	FUBP3
SPEN	ENSG00000065526.6	1881.51530	2510.87170	-0.41630	2.43580	1.38480	HepG2	FUS
SPEN	ENSG00000065526.6	2224.45240	1770.23450	0.32940	2.19100	1.59590	HepG2	G3BP1
SPEN	ENSG00000065526.6	2756.27880	1879.55590	0.55220	6.08760	4.75620	HepG2	G3BP2
SPEN	ENSG00000065526.6	3245.66960	4040.04480	-0.31590	2.25600	1.67450	HepG2	GPKOW
SPEN	ENSG00000065526.6	1275.22490	2001.57220	-0.65040	9.62110	8.52380	HepG2	HNRNPA1
SPEN	ENSG00000065526.6	2512.18470	1792.92480	0.48650	5.30490	4.36100	HepG2	HNRNPK
SPEN	ENSG00000065526.6	1970.37950	2196.46170	-0.15670	1.95710	1.37820	HepG2	HNRNPL
SPEN	ENSG00000065526.6	2344.46350	2844.30640	-0.27880	2.70410	1.76300	HepG2	HNRNPM
SPEN	ENSG00000065526.6	2350.31190	1809.94660	0.37680	2.23170	1.34360	HepG2	KHSRP
SPEN	ENSG00000065526.6	1483.74970	1853.44720	-0.32100	2.70990	1.58770	HepG2	LARP7
SPEN	ENSG00000065526.6	2938.16890	1909.16030	0.62190	7.15480	6.11610	HepG2	MAGOH
SPEN	ENSG00000065526.6	2763.36650	3336.35190	-0.27180	2.60070	1.81640	HepG2	MSI2
SPEN	ENSG00000065526.6	3117.37960	1964.97100	0.66570	7.76220	6.72700	HepG2	NCBP2
SPEN	ENSG00000065526.6	1305.48500	1675.88340	-0.36030	3.03610	1.55640	HepG2	NIP7
SPEN	ENSG00000065526.6	4157.95410	3418.80420	0.28230	2.24210	1.56620	HepG2	NSUN2
SPEN	ENSG00000065526.6	2976.12730	2071.50920	0.52270	2.79260	1.90100	HepG2	PABPC1
SPEN	ENSG00000065526.6	2476.87660	1749.73600	0.50130	4.68510	3.75630	HepG2	PABPC4
SPEN	ENSG00000065526.6	2768.95450	1797.72950	0.62310	2.31880	1.75320	HepG2	PCBP1
SPEN	ENSG00000065526.6	4255.06300	3126.34560	0.44460	10.03470	8.69830	HepG2	PRPF4
SPEN	ENSG00000065526.6	1103.10320	1426.12960	-0.37050	2.70470	1.90530	HepG2	PRPF8
SPEN	ENSG00000065526.6	3350.95040	2422.71990	0.46780	14.10310	12.98140	HepG2	PUM1
SPEN	ENSG00000065526.6	3130.74550	2420.98160	0.37080	4.72810	3.86290	HepG2	PUM2
SPEN	ENSG00000065526.6	2302.29410	2894.31540	-0.33020	6.29000	5.42890	HepG2	PUS1
SPEN	ENSG00000065526.6	2615.89230	1980.95210	0.40100	3.85400	3.13320	HepG2	QKI
SPEN	ENSG00000065526.6	2672.84470	3286.76240	-0.29830	4.10760	3.50830	HepG2	RBM22
SPEN	ENSG00000065526.6	2926.82550	1797.97840	0.70290	13.66350	12.23200	HepG2	RBM25
SPEN	ENSG00000065526.6	2599.23600	1896.36030	0.45480	5.07250	4.27020	HepG2	RECQL
SPEN	ENSG00000065526.6	1405.01660	1979.10660	-0.49430	6.23710	5.35540	HepG2	RPS19
SPEN	ENSG00000065526.6	1629.61980	2061.21850	-0.33900	2.69840	1.90680	HepG2	RPS2
SPEN	ENSG00000065526.6	1653.29400	2276.16520	-0.46130	3.01750	2.18290	HepG2	RPS3A
SPEN	ENSG00000065526.6	4844.21990	3816.06630	0.34410	3.31400	2.54850	HepG2	SF3B1
SPEN	ENSG00000065526.6	2973.23430	1904.36470	0.64260	13.36470	12.21830	HepG2	SF3B4
SPEN	ENSG00000065526.6	3037.29470	2188.27390	0.47290	13.00150	11.67540	HepG2	SLBP
SPEN	ENSG00000065526.6	2411.81230	1987.86890	0.27880	2.47270	2.01920	HepG2	SRSF1
SPEN	ENSG00000065526.6	2915.14660	2253.38600	0.37140	5.90510	5.04050	HepG2	SRSF5
SPEN	ENSG00000065526.6	3517.96550	3016.19390	0.22190	2.70290	2.01440	HepG2	SRSF7
SPEN	ENSG00000065526.6	2161.69840	1617.34450	0.41840	4.53170	3.85770	HepG2	SRSF9
SPEN	ENSG00000065526.6	2659.88440	3223.02650	-0.27710	4.50720	3.88440	HepG2	SSB
SPEN	ENSG00000065526.6	3173.54780	2562.77230	0.30830	4.69720	3.92430	HepG2	SUCLG1
SPEN	ENSG00000065526.6	1262.00570	1840.57120	-0.54440	5.03360	4.16460	HepG2	SUPV3L1
SPEN	ENSG00000065526.6	2349.15610	1787.11960	0.39440	4.27480	3.60140	HepG2	TAF15
SPEN	ENSG00000065526.6	2157.39970	1641.75280	0.39400	4.33530	3.29770	HepG2	TIA1
SPEN	ENSG00000065526.6	3126.97230	2229.63570	0.48790	6.95270	5.46690	HepG2	TUFM
SPEN	ENSG00000065526.6	6781.87440	3526.54490	0.94330	20.03020	18.29170	HepG2	U2AF1
SPEN	ENSG00000065526.6	758.09720	1087.24050	-0.52020	4.51270	3.54180	HepG2	UCHL5
SPEN	ENSG00000065526.6	3601.69250	4536.65390	-0.33300	7.16250	6.12620	HepG2	UPF1
SPEN	ENSG00000065526.6	1055.51580	1685.23930	-0.67500	5.33150	3.91340	HepG2	UPF2
SPEN	ENSG00000065526.6	1521.28620	2038.79580	-0.42240	2.45860	1.43400	HepG2	XPO5
SPEN	ENSG00000065526.6	1102.87360	1811.84230	-0.71620	8.96940	7.68160	HepG2	XRN2
SPEN	ENSG00000065526.6	2737.37510	3085.34390	-0.17260	2.32550	1.70290	HepG2	ZC3H8
SPEN	ENSG00000065526.6	4001.15640	4989.44890	-0.31850	8.55980	7.73370	HepG2	ZNF622
SPEN	ENSG00000065526.6	5688.03690	9385.84400	-0.72260	32.41850	30.56340	K562	AGGF1
SPEN	ENSG00000065526.6	4184.05850	5028.18210	-0.26510	3.73330	1.95910	K562	AKAP1
SPEN	ENSG00000065526.6	7958.96160	10313.62030	-0.37390	4.30570	3.02150	K562	AKAP8
SPEN	ENSG00000065526.6	6792.96170	9766.39530	-0.52380	7.93510	6.77410	K562	AKAP8L
SPEN	ENSG00000065526.6	16960.33700	8133.26460	1.06020	29.79390	28.07020	K562	AQR
SPEN	ENSG00000065526.6	8790.47920	10247.29810	-0.22120	2.69520	1.79420	K562	ATP5C1
SPEN	ENSG00000065526.6	6067.14560	4724.78640	0.36070	2.57190	1.56370	K562	CCAR1
SPEN	ENSG00000065526.6	18768.99530	12985.78670	0.53130	3.07740	1.94950	K562	CNOT7
SPEN	ENSG00000065526.6	4404.15980	5165.32440	-0.23000	2.79580	1.47920	K562	DDX6
SPEN	ENSG00000065526.6	7334.47140	5307.79720	0.46650	5.58440	4.26130	K562	EFTUD2
SPEN	ENSG00000065526.6	9207.02980	5322.65240	0.79050	16.74970	14.59660	K562	EIF4A3
SPEN	ENSG00000065526.6	17312.32910	13976.81980	0.30870	6.23940	4.84550	K562	EIF4G2
SPEN	ENSG00000065526.6	7027.25990	9992.78810	-0.50790	3.61040	2.63160	K562	FIP1L1
SPEN	ENSG00000065526.6	6831.47430	5535.32340	0.30340	4.10750	3.39190	K562	FXR1
SPEN	ENSG00000065526.6	7596.23920	6118.43280	0.31200	3.72510	3.04530	K562	HNRNPC
SPEN	ENSG00000065526.6	5296.27790	8218.80710	-0.63400	5.74000	4.33330	K562	HNRNPM
SPEN	ENSG00000065526.6	7063.81560	13548.66550	-0.93960	17.23770	15.37760	K562	HSPD1
SPEN	ENSG00000065526.6	7177.52490	10364.58940	-0.53010	8.32060	6.68830	K562	KIF1C
SPEN	ENSG00000065526.6	8013.33720	5449.75880	0.55610	9.53370	7.91440	K562	MAGOH
SPEN	ENSG00000065526.6	7488.81690	9921.46000	-0.40580	4.76750	3.24110	K562	MAK16
SPEN	ENSG00000065526.6	11799.00530	10282.87870	0.19830	2.92340	2.09160	K562	MTPAP
SPEN	ENSG00000065526.6	5505.98730	8138.44020	-0.56380	5.10270	3.78130	K562	NAA15
SPEN	ENSG00000065526.6	7157.10840	4848.62530	0.56170	9.25140	7.43600	K562	PCBP2
SPEN	ENSG00000065526.6	6917.57380	11343.20870	-0.71350	11.72400	9.69300	K562	PPIG
SPEN	ENSG00000065526.6	5009.74140	9685.59120	-0.95110	21.55090	20.06160	K562	PUS1
SPEN	ENSG00000065526.6	5945.24610	9437.14380	-0.66660	19.38810	17.78370	K562	RBM15
SPEN	ENSG00000065526.6	6004.79390	5005.00930	0.26260	2.94570	1.92140	K562	RCC2
SPEN	ENSG00000065526.6	3812.41290	5261.09230	-0.46470	4.29790	3.27620	K562	RPS19
SPEN	ENSG00000065526.6	3852.47300	5280.94390	-0.45500	3.27070	1.82580	K562	RRP9
SPEN	ENSG00000065526.6	14668.36130	11273.39010	0.37970	6.67000	5.45170	K562	SF3A3
SPEN	ENSG00000065526.6	7209.05750	4347.46480	0.72950	18.87820	16.45820	K562	SF3B4
SPEN	ENSG00000065526.6	11392.98800	7340.32660	0.63410	2.73910	1.51770	K562	SNRNP200
SPEN	ENSG00000065526.6	5729.10970	4744.62260	0.27190	2.44480	1.49570	K562	SRFBP1
SPEN	ENSG00000065526.6	13006.03580	11549.73290	0.17120	2.29970	1.43800	K562	SRPK2
SPEN	ENSG00000065526.6	6713.81100	5190.96720	0.37100	5.12160	4.16370	K562	SRSF1
SPEN	ENSG00000065526.6	6310.42400	5236.25250	0.26910	2.46540	1.47950	K562	SRSF4
SPEN	ENSG00000065526.6	6280.69020	5000.67430	0.32870	2.52770	1.56180	K562	SUPV3L1
SPEN	ENSG00000065526.6	6317.90550	5253.18600	0.26620	2.08190	1.46180	K562	TARDBP
SPEN	ENSG00000065526.6	5907.98530	4052.77910	0.54370	5.67220	3.98560	K562	U2AF1
SPEN	ENSG00000065526.6	5452.35100	4185.50780	0.38140	5.55840	4.42230	K562	U2AF2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SPEN is not available on ENCORE database.

9 RBPs can affect the splicing of SPEN :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SPEN	ENSG00000065526.6	chr1	+	16265212	16265371	16264306	16264501	16265790	16266955	-0.24100	0.00000	0.00013	excluded	K562	PRPF8
SE	SPEN	ENSG00000065526.6	chr1	+	16265212	16265371	16264306	16264501	16265790	16266955	-0.23000	0.00000	0.00000	excluded	HepG2	U2AF1
SE	SPEN	ENSG00000065526.6	chr1	+	16245898	16246012	16245420	16245546	16247364	16247401	-0.05500	0.00120	0.01645	excluded	HepG2	U2AF2
SE	SPEN	ENSG00000065526.6	chr1	+	16265212	16265371	16264306	16264501	16265790	16266955	-0.21900	0.00000	0.00000	excluded	K562	AQR
SE	SPEN	ENSG00000065526.6	chr1	+	16265212	16265371	16264306	16264501	16265790	16266955	-0.08000	0.00031	0.06133	excluded	K562	APOBEC3C
SE	SPEN	ENSG00000065526.6	chr1	+	16265212	16265371	16264306	16264501	16265790	16266955	-0.15000	0.00032	0.02124	excluded	K562	EFTUD2
SE	SPEN	ENSG00000065526.6	chr1	+	16265212	16265371	16264306	16264501	16265790	16266955	-0.17100	0.00000	0.00000	excluded	K562	SF3B1
SE	SPEN	ENSG00000065526.6	chr1	+	16265212	16265371	16264306	16264501	16265790	16266955	-0.05900	0.00253	0.04108	excluded	K562	HNRNPC
A3SS	SPEN	ENSG00000065526.6	chr1	+	16235791	16235976	16235815	16235976	16202696	16203173	0.13600	0.00000	0.00003	longer	K562	AQR
RI	SPEN	ENSG00000065526.6	chr1	+	16263657	16264140	16263657	16263885	16263981	16264140	0.06000	0.00000	0.00003	included	HepG2	U2AF1
RI	SPEN	ENSG00000065526.6	chr1	+	16263657	16264140	16263657	16263885	16263981	16264140	-0.07400	0.00003	0.00506	excluded	K562	FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SPEN

General Information

Functions

Localization

Domains (AlphaFold: SPEN)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SPEN is not avaliable on ENCORE database.

61 proteins are bound to SPEN RNA:

eCLIP assay for SPEN is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SPEN is not available on ENCORE database.

100 RBPs can affect the gene expression of SPEN :

The Knockdown/knockout RNA-Seq assay for SPEN is not available on ENCORE database.

9 RBPs can affect the splicing of SPEN :

The Knockdown/knockout RNA-Seq assay for SPEN is not avaliable on ENCORE database.