EXOC1

General Information

Gene Name       : EXOC1
Gene ID             : ENSG00000090989.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EXOC1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXOC1ENSG00000090989.1722.2124.8923.55ENCSR000AEF
HepG2EXOC1ENSG00000090989.177.0810.768.92ENCSR985KAT
K562EXOC1ENSG00000090989.1730.8930.6030.75ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EXOC1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EXOC1 RNA is bound by 15 proteins.  







eCLIP assay for EXOC1 is not avaliable on ENCORE database.





15 proteins are bound to EXOC1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr45677098656771059+3'-UTR3.432964.39516K562PUM2
chr45677107656771129+3'-UTR4.876828.78414K562PUM2
chr45671989556720005+5'-UTR,intron-Proximal4.109955.63105K562DDX3X
chr45672459756724614+CDS,intron-Proximal3.442173.95301K562ZNF622
chr45673721656737297+CDS,intron-Proximal4.6816813.78274K562SF3B4
chr45676865656768702+CDS3.673813.66187K562ZNF622
chr45675642756756489+CDS3.203004.00731K562UCHL5
chr45673689856737073+CDS,intron-Proximal3.2989814.42925K562UCHL5
chr45674407756744157+CDS,intron-Proximal3.616373.16095HepG2U2AF2
chr45673722656737302+CDS,intron-Proximal3.857019.18050K562BUD13
chr45673454056734658+CDS3.061105.29004K562GRWD1
chr45675497356755060+CDS,intron-Distal,intron-Proximal3.948383.06537K562RBFOX2
chr45676299456763044+CDS3.331564.92880K562ZNF622
chr45673689056737015+CDS3.6187212.48200K562ZNF622
chr45673692456737074+CDS,intron-Proximal3.898139.93259HepG2BCLAF1
chr45676300656763056+CDS4.587264.72838K562UCHL5
chr45677050856770573+CDS,intron-Proximal5.007556.13315HepG2BCLAF1
chr45672657656726605+CDS,intron-Proximal3.718565.14848K562ZNF622
chr45674404656744167+CDS,intron-Proximal3.7095712.32933K562SF3B4
chr45675639056756461+CDS3.632623.05298K562GRWD1
chr45673701556737076+CDS,intron-Proximal4.086929.36792K562ZNF622
chr45674406956744141+CDS,intron-Proximal5.4352111.99917K562U2AF2
chr45673807256738119+CDS3.185173.78791K562RBM15
chr45673464456734691+CDS,intron-Proximal3.321415.15500HepG2BCLAF1
chr45673722656737339+CDS,intron-Proximal3.039605.48288K562PRPF8
chr45675509156755182+CDS,intron-Distal,intron-Proximal3.307644.56724K562KHSRP
chr45675007056750089+CDS3.302113.31745K562ZNF622
chr45674372956743799+intron-Distal4.054997.46973K562KHSRP
chr45674959756749700+intron-Distal3.505139.27366K562KHSRP
chr45673813456738249+intron-Distal,intron-Proximal3.047704.23631K562KHSRP
chr45675491456755051+intron-Distal,intron-Proximal3.693514.13575K562KHSRP
chr45674112856741224+intron-Distal4.5858114.84176K562U2AF2
chr45673862256738697+intron-Distal3.409884.52210K562KHSRP
chr45673309156733177+intron-Distal4.289835.46313K562KHSRP
chr45674113856741205+intron-Distal3.161813.12916K562U2AF1
chr45674976256749858+intron-Distal5.3237511.14062K562KHSRP
chr45674379956743927+intron-Distal3.391927.78760K562KHSRP
chr45674986656749937+intron-Distal,intron-Proximal4.486544.96658K562KHSRP
chr45674397356744026+intron-Distal,intron-Proximal5.021107.79026K562TIA1
chr45674970056749757+intron-Distal4.111459.20471K562KHSRP
chr45674402756744082+intron-Proximal4.105968.34041K562KHSRP
chr45673714556737226+intron-Proximal4.020944.95247K562PRPF8
chr45674399556744027+intron-Proximal3.706009.89511K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EXOC1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EXOC1 is not available on ENCORE database.

  • 45 RBPs can affect the levels of EXOC1.  








The Knockdown/knockout RNA-Seq assay for EXOC1 is not available on ENCORE database.





45 RBPs can affect the gene expression of EXOC1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXOC1ENSG00000090989.131001.40520521.200100.942009.519308.59750HepG2AKAP1
EXOC1ENSG00000090989.13633.66230494.144900.358702.330801.61860HepG2CALR
EXOC1ENSG00000090989.13575.14970466.951000.300602.273801.66190HepG2CKAP4
EXOC1ENSG00000090989.13442.95610646.28720-0.545006.870305.78020HepG2DAZAP1
EXOC1ENSG00000090989.13594.35480384.757000.627305.172104.27300HepG2DDX21
EXOC1ENSG00000090989.13674.86760434.096700.636504.834203.84570HepG2DDX55
EXOC1ENSG00000090989.13320.44100428.88290-0.420501.824801.31300HepG2DDX6
EXOC1ENSG00000090989.13752.81650465.195200.694404.811503.81930HepG2FIP1L1
EXOC1ENSG00000090989.13423.95150532.95200-0.330102.135501.49880HepG2HNRNPF
EXOC1ENSG00000090989.13636.37680462.451400.460502.522801.91790HepG2MATR3
EXOC1ENSG00000090989.13496.53200376.489400.399202.301501.56100HepG2MSI2
EXOC1ENSG00000090989.13549.90820443.471400.310202.102701.35650HepG2PARN
EXOC1ENSG00000090989.13332.09310417.90370-0.331602.032701.36270HepG2PRPF4
EXOC1ENSG00000090989.13555.62050335.026200.729706.087004.94000HepG2PRPF8
EXOC1ENSG00000090989.13611.86690454.449000.429003.600202.99370HepG2PTBP1
EXOC1ENSG00000090989.13760.35760441.618900.783804.407603.52880HepG2RAVER1
EXOC1ENSG00000090989.131246.29280712.594800.8064015.2039014.18920HepG2RBM22
EXOC1ENSG00000090989.13672.60230505.746600.411203.488802.89650HepG2NELFE
EXOC1ENSG00000090989.13431.27540290.456600.570203.908203.18920HepG2RPS19
EXOC1ENSG00000090989.13562.30850443.684300.341702.130101.42300HepG2RPS2
EXOC1ENSG00000090989.13483.78210331.425600.545603.377302.51990HepG2RRP9
EXOC1ENSG00000090989.131105.27960804.844800.457506.444705.76710HepG2SRFBP1
EXOC1ENSG00000090989.13740.31210493.840000.584006.776806.11660HepG2SRSF1
EXOC1ENSG00000090989.13565.41910401.773900.492804.879504.18510HepG2SRSF9
EXOC1ENSG00000090989.13295.51920397.93900-0.429302.098701.54380HepG2U2AF1
EXOC1ENSG00000090989.13235.32280490.97630-1.061002.993701.96350HepG2U2AF2
EXOC1ENSG00000090989.13619.28950434.144400.512302.495801.30770HepG2XRCC5
EXOC1ENSG00000090989.13661.67750417.410600.664609.571908.70930HepG2ZNF622
EXOC1ENSG00000090989.132080.086201717.270400.276401.892601.39000K562AQR
EXOC1ENSG00000090989.13768.065201050.79930-0.452203.935802.95930K562EIF4A3
EXOC1ENSG00000090989.13765.93880946.33180-0.305102.471201.40020K562EIF4B
EXOC1ENSG00000090989.131748.741401165.242900.585604.530503.57820K562G3BP2
EXOC1ENSG00000090989.131224.350401525.78110-0.317502.622601.88570K562GRSF1
EXOC1ENSG00000090989.13627.67390850.96550-0.439102.753501.82650K562HNRNPM
EXOC1ENSG00000090989.13994.256901377.30040-0.470203.344602.17780K562IGF2BP2
EXOC1ENSG00000090989.13954.59590701.928400.443502.503301.61830K562KRR1
EXOC1ENSG00000090989.13916.822501447.79410-0.659109.181807.59480K562MAGOH
EXOC1ENSG00000090989.131041.460401444.90340-0.472405.420004.07100K562MATR3
EXOC1ENSG00000090989.13884.043901406.59980-0.6700010.182208.96370K562PTBP1
EXOC1ENSG00000090989.133083.851202584.306900.254902.434801.43860K562PUM1
EXOC1ENSG00000090989.13917.693301348.92810-0.555706.108804.79760K562RBM22
EXOC1ENSG00000090989.13989.415901314.81980-0.410203.201901.67090K562RBM34
EXOC1ENSG00000090989.131156.29910799.996800.531304.165403.16170K562RPS19
EXOC1ENSG00000090989.13942.704601211.61900-0.362103.520402.55180K562SF3B4
EXOC1ENSG00000090989.13777.500501039.98400-0.419603.310002.14420K562SRSF4
EXOC1ENSG00000090989.131097.765501395.61320-0.346302.545301.86510K562TARDBP
EXOC1ENSG00000090989.13975.744401346.20710-0.464305.119303.95420K562TIA1
EXOC1ENSG00000090989.131328.252101080.462400.297802.428101.60630K562WDR3
EXOC1ENSG00000090989.132326.900001934.289700.266502.187401.43080K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EXOC1 is not available on ENCORE database.





19 RBPs can affect the splicing of EXOC1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEXOC1ENSG00000090989.13chr4+567574805675758856756388567565525675880056758877-0.088000.002210.03946excludedK562SRSF1
SEEXOC1ENSG00000090989.13chr4+567574805675758856756388567565525675880056758877-0.142000.000010.00057excludedK562SF3B4
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.192000.001430.07806includedHepG2RBM22
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.519000.000160.00429includedHepG2U2AF1
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.438000.000520.06518includedHepG2HNRNPM
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.218000.000120.01633includedK562XRCC6
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.457000.000000.00210includedHepG2DKC1
SEEXOC1ENSG00000090989.13chr4+5674372956743923567380145673812456744082567442320.074000.002000.02186includedK562AQR
SEEXOC1ENSG00000090989.13chr4+567499885675009456744017567442325675638856756552-0.058000.001980.02171excludedK562AQR
SEEXOC1ENSG00000090989.13chr4+567380145673812456737163567373995674408256744232-0.115000.000110.00183excludedK562AQR
SEEXOC1ENSG00000090989.13chr4+567588005675887756757459567575885675971756759793-0.068000.000480.00658excludedK562AQR
SEEXOC1ENSG00000090989.13chr4+567658505676605056762882567630665676850956768704-0.055000.005490.05020excludedK562AQR
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.243000.000000.00000includedK562FXR1
SEEXOC1ENSG00000090989.13chr4+567466265674682556744082567442325674998856750094-0.146000.000650.07954excludedK562DROSHA
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.143000.000010.00408includedK562APOBEC3C
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.403000.000000.00093includedK562HNRNPM
SEEXOC1ENSG00000090989.13chr4+567550535675509856749988567500945675638856756552-0.286000.003810.07224excludedHepG2SRSF1
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.434000.000040.02514includedHepG2GRSF1
SEEXOC1ENSG00000090989.13chr4+567550535675509856749988567500945675638856756552-0.370000.001200.05345excludedHepG2SF3B4
SEEXOC1ENSG00000090989.13chr4+5674662656746825567440825674423256749988567500940.122000.000020.00062includedK562U2AF2
SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.300000.000000.00000includedK562TARDBP
SEEXOC1ENSG00000090989.13chr4+567574805675758856756388567565525675871056758877-0.062000.001890.04419excludedK562RBM15
SEEXOC1ENSG00000090989.13chr4+567550535675509856749988567500945675638856756552-0.443000.000520.03815excludedHepG2SRSF9
SEEXOC1ENSG00000090989.13chr4+5673892056738974567380145673812456744082567442320.106000.001250.04756includedK562PTBP1
SEEXOC1ENSG00000090989.13chr4+5673892056738974567380145673812456744082567442320.155000.006430.08449includedK562HNRNPC
A3SSEXOC1ENSG00000090989.13chr4+5675871056758877567588005675887756757480567575880.127000.000000.00005longerK562U2AF2
A3SSEXOC1ENSG00000090989.13chr4+5676283256763066567628825676306656759717567599460.063000.000010.00008longerK562AQR
A3SSEXOC1ENSG00000090989.13chr4+5672655756726707567265765672670756724479567246130.108000.000030.00031longerK562AQR
A3SSEXOC1ENSG00000090989.13chr4+5675871056758877567588005675887756757480567575880.063000.001100.04951longerK562U2AF1
MXEEXOC1ENSG00000090989.13chr4+5674998856750094567550535675509856744082567442325675638856756552-0.436000.001010.021382includedHepG2U2AF1
MXEEXOC1ENSG00000090989.13chr4+56757459567575885675865756758877567563725675655256759717567598070.139000.000000.000051includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+56757459567575885675871056758877567563725675655256759717567598070.134000.000000.000071includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+56757445567575885675871056758877567563725675655256759717567597930.106000.000400.004111includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+56757445567575885675865756758877567563725675655256759717567597930.111000.000310.003311includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+56757433567575885675871056758877567563725675655256759717567597930.080000.001140.010241includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+56757433567575885675865756758877567563725675655256759717567597930.083000.000910.008391includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+56756388567565525675971756759946567440825674423256762882567630660.069000.000750.007131includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+5673801456738124567436875674392356737266567373995674408256744232-0.074000.001480.012832includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+5673801456738124567437295674392356737266567373995674408256744232-0.069000.003020.023582includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+5673793656738124567436875674392356737195567373995674408256744232-0.133000.001600.013702includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+5673793656738124567437295674392356737195567373995674408256744232-0.124000.003160.024482includedK562AQR
MXEEXOC1ENSG00000090989.13chr4+5675748056757588567588005675887756756388567565525675971756759946-0.192000.001870.037522includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EXOC1 is not avaliable on ENCORE database.