YARS

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	YARS	ENSG00000134684.10	139.07	122.09	130.58	ENCSR000AEF
HepG2	YARS	ENSG00000134684.10	68.11	77.94	73.03	ENCSR985KAT
K562	YARS	ENSG00000134684.10	225.23	222.25	223.74	ENCSR000AEO

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
YARS		A305-064A	1				BGHcLV45-81, Experimented, ENCORE2	BGKcLV44-85, Submitting, ENCORE2

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
YARS	K562	CRISPR	BGKcLV37-61,BGKcLV37-62	BGKcLV37-1,BGKcLV37-2	no change/too many bands,	NotSatisfied	ENCORE2
YARS	K562	CRISPR	YARS-BGKcLV44-85,YARS-BGKcLV44-86	NT-BGKcLV44-1,NT-BGKcLV44-2	63.4,60.5	Sequenced	ENCORE2
YARS	K562	CRISPR	BGKcLV44-87,BGKcLV44-88	BGKcLV44-1,BGKcLV44-2	58.6,53.6	NotSatisfied	ENCORE2
YARS	HepG2	CRISPR	BGHcLV36-59,BGHcLV36-60	BGHcLV36-1,BGHcLV36-2	0.0,0.0	NotSatisfied	ENCORE2
YARS	HepG2	CRISPR	BGHcLV45-81,BGHcLV45-82	BGHcLV45-1,BGHcLV45-2	65.5,63.7	Sequencing	ENCORE2

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for YARS is not avaliable on ENCORE database.

Proteins bound to RNA

YARS RNA is bound by 44 proteins.

eCLIP assay for YARS is not avaliable on ENCORE database.

44 proteins are bound to YARS RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	33241499	33241579	-	3'-UTR,intron-Distal,intron-Proximal	3.11514	17.80244	K562	RPS3
chr1	33241353	33241434	-	3'-UTR,intron-Distal	3.31406	6.89814	K562	METAP2
chr1	33241443	33241505	-	3'-UTR,intron-Distal,intron-Proximal	4.11004	17.99896	K562	IGF2BP2
chr1	33240977	33241013	-	3'-UTR,intron-Distal	4.17646	18.73632	K562	UPF1
chr1	33241162	33241176	-	3'-UTR,intron-Distal	3.09286	3.57974	K562	IGF2BP1
chr1	33241228	33241280	-	3'-UTR,intron-Distal,intron-Proximal	3.58915	3.81856	K562	IGF2BP1
chr1	33240931	33240977	-	3'-UTR,intron-Distal	3.26597	15.75853	K562	UPF1
chr1	33241013	33241105	-	3'-UTR,intron-Distal	3.48703	20.18162	K562	UPF1
chr1	33241168	33241222	-	3'-UTR,intron-Distal,intron-Proximal	3.76552	6.73288	K562	IGF2BP2
chr1	33240912	33240970	-	3'-UTR,intron-Distal	5.07235	8.79791	HepG2	SUB1
chr1	33241178	33241238	-	3'-UTR,intron-Distal,intron-Proximal	3.19261	20.51086	K562	UPF1
chr1	33241389	33241442	-	3'-UTR,intron-Distal	3.49756	5.25229	K562	IGF2BP2
chr1	33241303	33241389	-	3'-UTR,intron-Distal	3.66606	7.19744	K562	IGF2BP2
chr1	33241029	33241105	-	3'-UTR,intron-Distal	3.61726	8.00779	HepG2	SUB1
chr1	33240860	33240897	-	3'-UTR,intron-Distal	4.46895	10.88945	K562	UPF1
chr1	33240893	33240986	-	3'-UTR,intron-Distal	3.94764	7.11514	K562	NOLC1
chr1	33241014	33241068	-	3'-UTR,intron-Distal	3.08727	6.71760	K562	IGF2BP2
chr1	33241300	33241338	-	3'-UTR,intron-Distal	3.38441	6.99055	K562	UPF1
chr1	33241450	33241558	-	3'-UTR,intron-Distal,intron-Proximal	3.85910	9.84119	K562	IGF2BP1
chr1	33240853	33240962	-	3'-UTR,intron-Distal	5.60323	8.90208	K562	IGF2BP1
chr1	33282792	33282908	-	5'-UTR,CDS,intron-Distal	3.06723	9.12772	K562	ZNF800
chr1	33282817	33282893	-	5'-UTR,CDS,intron-Distal	3.65470	11.98644	K562	GEMIN5
chr1	33282791	33282913	-	5'-UTR,CDS,intron-Distal	3.37588	13.05825	K562	DROSHA
chr1	33282834	33282936	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.11246	14.93256	K562	RPS3
chr1	33245058	33245124	-	CDS,intron-Distal	3.67368	3.93645	HepG2	PPIG
chr1	33276545	33276607	-	CDS,intron-Distal	3.00178	15.18285	K562	ZNF622
chr1	33256762	33256846	-	CDS,intron-Distal,intron-Proximal	3.36147	5.50236	K562	SRSF1
chr1	33272082	33272106	-	CDS,intron-Distal,intron-Proximal	3.67092	3.72080	K562	FXR2
chr1	33276531	33276621	-	CDS,intron-Distal	4.08275	10.78406	HepG2	BCLAF1
chr1	33252476	33252547	-	CDS,intron-Distal,intron-Proximal	3.98050	7.77750	HepG2	PRPF8
chr1	33282781	33282817	-	CDS,intron-Distal	3.11413	3.94602	K562	GEMIN5
chr1	33252026	33252138	-	CDS,intron-Distal,intron-Proximal	4.80997	3.82050	HepG2	SF3B4
chr1	33245045	33245103	-	CDS,intron-Distal	3.18732	4.24789	K562	SRSF1
chr1	33252651	33252677	-	CDS,intron-Distal,intron-Proximal	3.28248	3.49777	K562	ZNF800
chr1	33263268	33263385	-	CDS,intron-Distal,intron-Proximal	3.56404	15.20903	K562	EFTUD2
chr1	33251962	33252036	-	CDS,intron-Distal,intron-Proximal	4.33763	3.11149	HepG2	G3BP1
chr1	33276264	33276361	-	CDS,intron-Distal,intron-Proximal	3.18535	5.33987	HepG2	GRWD1
chr1	33245716	33245772	-	CDS,intron-Distal	3.20118	3.17464	K562	DDX6
chr1	33245741	33245804	-	CDS,intron-Distal	4.47056	21.47848	K562	RPS3
chr1	33276621	33276657	-	CDS,intron-Distal	3.08034	3.55800	HepG2	BCLAF1
chr1	33276511	33276607	-	CDS,intron-Distal,intron-Proximal	3.56774	10.16880	K562	LIN28B
chr1	33272048	33272100	-	CDS,intron-Distal,intron-Proximal	4.56647	14.23871	HepG2	PRPF8
chr1	33263415	33263444	-	CDS,intron-Distal	5.06031	4.08330	K562	FXR2
chr1	33248066	33248140	-	CDS,intron-Distal	3.20968	7.88565	HepG2	GRWD1
chr1	33272080	33272159	-	CDS,intron-Distal,intron-Proximal	3.64955	7.57199	K562	FMR1
chr1	33276645	33276658	-	CDS,intron-Distal	4.98196	3.86495	K562	DDX24
chr1	33276607	33276627	-	CDS,intron-Distal	3.29057	3.19733	K562	ZNF622
chr1	33263347	33263365	-	CDS,intron-Distal,intron-Proximal	3.18476	8.65113	K562	AQR
chr1	33276550	33276608	-	CDS,intron-Distal	3.35980	5.54854	HepG2	GRWD1
chr1	33246743	33246794	-	CDS,intron-Distal,intron-Proximal	3.92872	6.84121	HepG2	SF3B4
chr1	33252645	33252665	-	CDS,intron-Distal	4.46914	3.38968	HepG2	BCLAF1
chr1	33256850	33256927	-	CDS,intron-Distal,intron-Proximal	4.30351	3.56713	HepG2	SF3B4
chr1	33276544	33276619	-	CDS,intron-Distal	3.16823	13.02019	K562	UCHL5
chr1	33245732	33245860	-	CDS,intron-Distal	3.96446	5.73518	HepG2	G3BP1
chr1	33252479	33252560	-	CDS,intron-Distal,intron-Proximal	3.58482	6.25219	HepG2	TIAL1
chr1	33245790	33245883	-	CDS,intron-Distal,intron-Proximal	3.43746	6.60490	HepG2	BCLAF1
chr1	33263396	33263444	-	CDS,intron-Distal	4.04905	3.80193	HepG2	GRWD1
chr1	33246648	33246671	-	CDS,intron-Distal,intron-Proximal	3.59170	5.15500	HepG2	BCLAF1
chr1	33276227	33276277	-	CDS,intron-Distal,intron-Proximal	3.12351	5.80673	K562	GRWD1
chr1	33246720	33246749	-	CDS,intron-Distal,intron-Proximal	3.12484	3.67408	K562	DDX24
chr1	33246717	33246747	-	CDS,intron-Distal,intron-Proximal	3.16518	6.58907	K562	YBX3
chr1	33241639	33241680	-	CDS,intron-Distal	3.52103	5.17903	K562	UCHL5
chr1	33244994	33245114	-	CDS,intron-Distal	3.78776	21.76060	K562	RPS3
chr1	33252474	33252544	-	CDS,intron-Distal,intron-Proximal	4.16955	10.55990	HepG2	TIA1
chr1	33245804	33245855	-	CDS,intron-Distal	3.77854	14.70344	K562	RPS3
chr1	33263362	33263398	-	CDS,intron-Distal,intron-Proximal	4.21118	5.57500	K562	SND1
chr1	33263377	33263456	-	CDS,intron-Distal,intron-Proximal	3.15662	4.00119	K562	SRSF1
chr1	33252655	33252676	-	CDS,intron-Distal	3.36023	3.34359	K562	SND1
chr1	33245772	33245825	-	CDS,intron-Distal	3.45121	4.34553	K562	DDX6
chr1	33252580	33252651	-	CDS,intron-Distal	4.31768	5.98894	K562	ZNF800
chr1	33276513	33276624	-	CDS,intron-Distal	3.10880	16.62004	K562	DDX24
chr1	33245613	33245704	-	CDS,intron-Distal,intron-Proximal	3.97726	6.79537	K562	AQR
chr1	33245687	33245777	-	CDS,intron-Distal	3.28283	7.51817	K562	PUM1
chr1	33276190	33276264	-	CDS,intron-Distal,intron-Proximal	3.77031	6.23335	HepG2	GRWD1
chr1	33263384	33263421	-	CDS,intron-Distal	3.09481	6.05977	K562	UCHL5
chr1	33245629	33245716	-	CDS,intron-Distal,intron-Proximal	4.74933	11.76457	HepG2	PRPF8
chr1	33276511	33276536	-	CDS,intron-Distal,intron-Proximal	3.25578	5.17903	K562	UCHL5
chr1	33252458	33252560	-	CDS,intron-Distal,intron-Proximal	3.00862	7.55249	K562	PRPF8
chr1	33246555	33246640	-	intron-Distal,intron-Proximal	5.03781	5.02942	K562	EFTUD2
chr1	33256178	33256242	-	intron-Distal,intron-Proximal	3.83670	6.83369	K562	ILF3
chr1	33244920	33244981	-	intron-Distal,intron-Proximal	3.90111	6.80869	K562	AQR
chr1	33257569	33257645	-	intron-Distal	3.13105	3.37567	HepG2	HNRNPK
chr1	33271977	33272048	-	intron-Distal,intron-Proximal	4.05283	7.64882	K562	PRPF8
chr1	33263201	33263254	-	intron-Distal,intron-Proximal	4.51315	4.79708	HepG2	U2AF2
chr1	33241705	33241737	-	intron-Distal	5.04163	4.90235	K562	SF3B4
chr1	33270801	33270854	-	intron-Distal	4.32457	4.07750	HepG2	HNRNPK
chr1	33263319	33263346	-	intron-Distal,intron-Proximal	3.23747	4.87883	K562	BUD13
chr1	33259885	33259955	-	intron-Distal	3.77468	8.89279	HepG2	HNRNPC
chr1	33266673	33266730	-	intron-Distal	3.46909	5.44125	K562	PTBP1
chr1	33258710	33258809	-	intron-Distal	3.78824	4.00631	HepG2	PTBP1
chr1	33256564	33256664	-	intron-Distal,intron-Proximal	3.64210	10.82143	K562	EFTUD2
chr1	33264194	33264222	-	intron-Distal	3.95854	3.24242	HepG2	HNRNPC
chr1	33255062	33255164	-	intron-Distal	3.70006	14.49681	K562	ILF3
chr1	33258710	33258812	-	intron-Distal	4.63472	18.67461	K562	PTBP1
chr1	33256876	33256919	-	intron-Distal,intron-Proximal	3.50970	4.89507	K562	SF3B4
chr1	33252423	33252465	-	intron-Distal,intron-Proximal	3.77386	8.82673	K562	TIA1
chr1	33263255	33263339	-	intron-Distal,intron-Proximal	4.16488	9.48330	K562	RBM22
chr1	33263274	33263345	-	intron-Distal,intron-Proximal	4.00008	16.05612	K562	AQR
chr1	33252465	33252527	-	intron-Distal,intron-Proximal	4.97198	47.94619	K562	TIA1
chr1	33271998	33272040	-	intron-Distal,intron-Proximal	3.96181	4.19412	K562	EFTUD2
chr1	33262903	33262973	-	intron-Distal	3.11813	5.65057	HepG2	HNRNPC
chr1	33262928	33262982	-	intron-Distal	3.23625	4.57936	K562	HNRNPC
chr1	33252491	33252534	-	intron-Distal,intron-Proximal	3.85465	12.17288	K562	EFTUD2
chr1	33264740	33264829	-	intron-Distal	3.63428	8.32412	K562	HNRNPL
chr1	33246556	33246634	-	intron-Distal,intron-Proximal	3.06066	6.64817	K562	TIA1
chr1	33255316	33255362	-	intron-Distal	4.03384	3.57543	K562	ILF3
chr1	33257869	33257947	-	intron-Distal	4.18923	3.62025	K562	MATR3
chr1	33267864	33267953	-	intron-Distal	4.31600	3.53509	HepG2	HLTF
chr1	33243404	33243531	-	intron-Distal	3.28934	3.07751	K562	KHSRP
chr1	33246762	33246827	-	intron-Distal,intron-Proximal	5.76371	36.15400	K562	SF3B4
chr1	33246794	33246822	-	intron-Distal,intron-Proximal	4.81896	8.09250	HepG2	SF3B4
chr1	33244904	33244982	-	intron-Distal,intron-Proximal	3.10269	6.71915	K562	PRPF8
chr1	33244886	33244960	-	intron-Distal,intron-Proximal	4.54646	8.70163	K562	RBM22
chr1	33270805	33270848	-	intron-Distal	4.46044	4.57427	HepG2	PCBP2
chr1	33259546	33259595	-	intron-Distal	3.14678	3.56409	K562	MATR3
chr1	33252051	33252135	-	intron-Distal,intron-Proximal	5.86768	16.36015	HepG2	RBFOX2
chr1	33258874	33258922	-	intron-Distal	3.17885	3.71597	K562	MATR3
chr1	33252050	33252096	-	intron-Distal,intron-Proximal	4.01692	16.80956	K562	SF3B4
chr1	33251864	33251956	-	intron-Distal,intron-Proximal	4.04634	5.95946	K562	KHSRP
chr1	33264829	33264898	-	intron-Distal	4.22271	4.02823	K562	HNRNPL
chr1	33266660	33266741	-	intron-Distal	3.96758	4.48652	HepG2	PTBP1
chr1	33266730	33266787	-	intron-Distal	4.89308	5.39854	K562	PTBP1
chr1	33267820	33267903	-	intron-Distal	4.21455	4.16170	K562	UCHL5
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for YARS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for YARS is not available on ENCORE database.
142 RBPs can affect the levels of YARS.

The Knockdown/knockout RNA-Seq assay for YARS is not available on ENCORE database.

142 RBPs can affect the gene expression of YARS :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
YARS	ENSG00000134684.6	1267.35030	792.02930	0.67810	8.40340	6.65130	HepG2	AATF
YARS	ENSG00000134684.6	881.12260	1291.81700	-0.55200	9.33500	8.02710	HepG2	AKAP8L
YARS	ENSG00000134684.6	2025.80090	3769.48530	-0.89590	22.99290	21.36440	HepG2	AUH
YARS	ENSG00000134684.6	1378.36430	1130.13730	0.28640	2.31600	1.60550	HepG2	CALR
YARS	ENSG00000134684.6	2016.45190	2484.53440	-0.30120	2.14040	1.45440	HepG2	CIRBP
YARS	ENSG00000134684.6	1347.89190	1746.25710	-0.37360	4.77230	3.97080	HepG2	CELF1
YARS	ENSG00000134684.6	1239.50350	873.75290	0.50440	5.04140	4.15390	HepG2	DDX21
YARS	ENSG00000134684.6	1240.57890	855.11370	0.53670	6.26850	4.89940	HepG2	DDX24
YARS	ENSG00000134684.6	1813.66810	3027.60970	-0.73930	9.65260	8.54530	HepG2	DDX3X
YARS	ENSG00000134684.6	5528.77610	2600.71120	1.08800	18.50130	17.09640	HepG2	DDX6
YARS	ENSG00000134684.6	1317.04850	1043.72230	0.33550	2.66290	1.69860	HepG2	DHX30
YARS	ENSG00000134684.6	1791.75100	1082.14830	0.72740	16.06700	14.50910	HepG2	DNAJC21
YARS	ENSG00000134684.6	1284.22450	1072.55430	0.25970	3.06720	2.38700	HepG2	DNAJC2
YARS	ENSG00000134684.6	824.75640	1093.73800	-0.40720	2.82990	1.89930	HepG2	EEF2
YARS	ENSG00000134684.6	1598.25040	804.66530	0.98990	11.49730	9.41020	HepG2	AGO1
YARS	ENSG00000134684.6	1353.83700	2500.19440	-0.88500	13.20830	11.98030	HepG2	EIF2S1
YARS	ENSG00000134684.6	3515.27570	1427.61030	1.29990	29.38020	26.35870	HepG2	EIF2S2
YARS	ENSG00000134684.6	1835.30270	2763.04140	-0.59020	5.58370	4.67610	HepG2	EIF4A3
YARS	ENSG00000134684.6	3846.02150	2690.14610	0.51560	3.76480	2.96820	HepG2	EIF4B
YARS	ENSG00000134684.6	2969.43330	1852.39610	0.68070	20.53870	18.70690	HepG2	EIF4G1
YARS	ENSG00000134684.6	1279.10540	1774.44470	-0.47220	4.49920	3.47650	HepG2	EIF4G2
YARS	ENSG00000134684.6	7045.89370	4328.17190	0.70290	26.83900	25.29510	HepG2	ETF1
YARS	ENSG00000134684.6	1036.68040	1256.43270	-0.27740	2.05110	1.33390	HepG2	EWSR1
YARS	ENSG00000134684.6	1135.48990	781.76160	0.53840	4.73830	2.53200	HepG2	EXOSC9
YARS	ENSG00000134684.6	559.08900	793.57130	-0.50530	4.98010	3.37560	HepG2	FAM120A
YARS	ENSG00000134684.6	842.61410	1133.23600	-0.42750	2.70710	1.45470	HepG2	FKBP4
YARS	ENSG00000134684.6	943.29350	1854.12380	-0.97500	19.66570	17.66350	HepG2	FUBP3
YARS	ENSG00000134684.6	1549.76040	2586.04700	-0.73870	8.96650	7.80370	HepG2	G3BP1
YARS	ENSG00000134684.6	1878.28830	2745.35240	-0.54760	5.98230	4.66040	HepG2	G3BP2
YARS	ENSG00000134684.6	2065.28470	1227.54870	0.75050	21.22110	18.95250	HepG2	HDGF
YARS	ENSG00000134684.6	939.97340	1215.20840	-0.37050	2.92530	2.21420	HepG2	HNRNPC
YARS	ENSG00000134684.6	2275.28380	2599.03910	-0.19190	1.92540	1.31970	HepG2	HNRNPF
YARS	ENSG00000134684.6	1443.35710	2618.48540	-0.85930	14.77240	13.28370	HepG2	HNRNPK
YARS	ENSG00000134684.6	1144.18100	1710.14780	-0.57980	13.77830	12.38360	HepG2	HNRNPL
YARS	ENSG00000134684.6	959.13490	1623.92900	-0.75970	9.68010	8.58180	HepG2	HNRNPLL
YARS	ENSG00000134684.6	1534.95570	2466.82700	-0.68450	2.42700	1.51350	HepG2	IGF2BP3
YARS	ENSG00000134684.6	1344.62220	2643.96710	-0.97550	11.81980	9.66330	HepG2	KHSRP
YARS	ENSG00000134684.6	1750.20290	1175.36100	0.57430	14.45250	12.35920	HepG2	KIF1C
YARS	ENSG00000134684.6	1795.36870	2788.66680	-0.63530	7.34760	6.29310	HepG2	MAGOH
YARS	ENSG00000134684.6	3832.14490	2804.29070	0.45040	3.81140	3.08060	HepG2	MATR3
YARS	ENSG00000134684.6	2031.91210	2870.36060	-0.49840	4.70820	3.89460	HepG2	NCBP2
YARS	ENSG00000134684.6	1525.30920	1194.91250	0.35210	4.59160	3.53180	HepG2	PARN
YARS	ENSG00000134684.6	2356.40150	2655.05690	-0.17220	1.87740	1.36060	HepG2	PCBP1
YARS	ENSG00000134684.6	1562.69260	1076.70600	0.53730	8.72540	7.46420	HepG2	PPIL4
YARS	ENSG00000134684.6	1657.00670	2701.57030	-0.70520	20.33990	19.11850	HepG2	PTBP1
YARS	ENSG00000134684.6	2261.66050	1777.19790	0.34770	3.59190	2.92410	HepG2	PUF60
YARS	ENSG00000134684.6	3626.31680	1886.64140	0.94260	51.81900	49.91730	HepG2	PUM1
YARS	ENSG00000134684.6	1559.88500	1885.22150	-0.27330	2.33880	1.72060	HepG2	PUM2
YARS	ENSG00000134684.6	2284.39680	1598.11530	0.51530	8.18860	6.81710	HepG2	RBM15
YARS	ENSG00000134684.6	2123.72810	2655.46850	-0.32240	3.03730	2.33470	HepG2	RBM25
YARS	ENSG00000134684.6	1676.60220	3006.62940	-0.84260	21.65720	20.42450	HepG2	NELFE
YARS	ENSG00000134684.6	2028.44950	2800.19210	-0.46510	10.13930	9.07450	HepG2	RECQL
YARS	ENSG00000134684.6	2027.75370	2799.62700	-0.46540	5.34200	4.43490	HepG2	RPLP0
YARS	ENSG00000134684.6	1338.16970	921.85790	0.53750	3.19340	2.18040	HepG2	RPS10
YARS	ENSG00000134684.6	1022.67910	1613.87850	-0.65820	2.70200	1.90980	HepG2	RPS2
YARS	ENSG00000134684.6	2009.98400	3095.06010	-0.62280	5.23710	4.13390	HepG2	RPS3A
YARS	ENSG00000134684.6	851.70910	1075.05030	-0.33600	3.96030	3.21300	HepG2	SAFB2
YARS	ENSG00000134684.6	2333.23110	1451.43030	0.68480	6.28550	5.24430	HepG2	SF3A3
YARS	ENSG00000134684.6	2412.65150	1607.32960	0.58590	7.59420	6.47710	HepG2	SF3B1
YARS	ENSG00000134684.6	3238.26750	2812.77200	0.20310	2.44280	1.88240	HepG2	SF3B4
YARS	ENSG00000134684.6	1372.56660	1704.19410	-0.31220	4.35500	3.50340	HepG2	SLBP
YARS	ENSG00000134684.6	952.91160	1788.45010	-0.90830	8.09950	6.76310	HepG2	SNRNP70
YARS	ENSG00000134684.6	2098.61750	2935.88880	-0.48440	11.98390	11.14760	HepG2	SRSF1
YARS	ENSG00000134684.6	1942.80510	2553.42970	-0.39430	6.89390	5.87640	HepG2	SRSF7
YARS	ENSG00000134684.6	3404.99240	2388.47080	0.51150	13.86060	12.79430	HepG2	SRSF9
YARS	ENSG00000134684.6	1870.03810	3547.17180	-0.92360	18.24660	17.17600	HepG2	SSB
YARS	ENSG00000134684.6	2096.40000	876.79350	1.25750	11.93470	9.59640	HepG2	SUB1
YARS	ENSG00000134684.6	2991.40970	1995.62740	0.58390	19.04490	17.64940	HepG2	SUCLG1
YARS	ENSG00000134684.6	783.71460	1355.32990	-0.79020	5.72350	4.80500	HepG2	SUPV3L1
YARS	ENSG00000134684.6	3444.34370	2638.79090	0.38430	6.11810	5.33960	HepG2	TAF15
YARS	ENSG00000134684.6	1974.03160	3616.59970	-0.87350	5.06020	3.65030	HepG2	TBRG4
YARS	ENSG00000134684.6	580.89520	908.33000	-0.64490	4.51210	3.28520	HepG2	TFIP11
YARS	ENSG00000134684.6	1701.41090	942.27540	0.85240	7.79050	5.43650	HepG2	TRA2A
YARS	ENSG00000134684.6	1123.10970	705.47190	0.67070	5.69980	3.51510	HepG2	TROVE2
YARS	ENSG00000134684.6	2252.47770	1625.39400	0.47060	2.53690	1.93310	HepG2	U2AF1
YARS	ENSG00000134684.6	2684.75230	1837.97900	0.54660	5.51080	4.30490	HepG2	UBE2L3
YARS	ENSG00000134684.6	943.38290	1287.19950	-0.44830	6.91370	5.89190	HepG2	UPF1
YARS	ENSG00000134684.6	1681.38750	922.82630	0.86540	7.85960	5.79150	HepG2	XRCC5
YARS	ENSG00000134684.6	1795.54940	1031.89890	0.79900	7.14090	5.50820	HepG2	XRCC6
YARS	ENSG00000134684.6	959.66370	1334.17870	-0.47540	2.86950	2.13090	HepG2	XRN2
YARS	ENSG00000134684.6	1345.77750	2588.32020	-0.94360	9.31660	8.20520	HepG2	ZC3H8
YARS	ENSG00000134684.6	2527.14860	1415.66920	0.83590	36.10630	34.71050	HepG2	ZNF622
YARS	ENSG00000134684.6	1792.65720	937.59420	0.93500	10.10150	7.52280	HepG2	ZRANB2
YARS	ENSG00000134684.6	6269.83710	10317.34110	-0.71860	13.02620	10.51110	K562	ABCF1
YARS	ENSG00000134684.6	2590.75070	5016.66050	-0.95340	5.35170	2.97810	K562	ADAR
YARS	ENSG00000134684.6	19157.19700	22459.53670	-0.22940	4.24400	3.56740	K562	AGGF1
YARS	ENSG00000134684.6	17261.42270	23370.23720	-0.43710	5.89290	4.91560	K562	AKAP8L
YARS	ENSG00000134684.6	7864.73190	13375.33470	-0.76610	15.28180	14.05500	K562	AQR
YARS	ENSG00000134684.6	21235.20980	24521.13920	-0.20760	2.49990	1.63510	K562	ATP5C1
YARS	ENSG00000134684.6	4450.15020	6810.04700	-0.61380	23.17650	20.55500	K562	BCLAF1
YARS	ENSG00000134684.6	3362.48350	5074.68010	-0.59380	3.10820	2.18210	K562	BOP1
YARS	ENSG00000134684.6	4548.03290	7186.67580	-0.66010	8.72000	6.20210	K562	BUD13
YARS	ENSG00000134684.6	2986.80280	4912.15170	-0.71780	11.79690	9.13770	K562	CCAR1
YARS	ENSG00000134684.6	7458.87030	10545.40150	-0.49960	3.79970	2.06550	K562	CKAP4
YARS	ENSG00000134684.6	5643.03400	13053.33590	-1.20990	4.08320	2.75120	K562	CNOT7
YARS	ENSG00000134684.6	6310.55510	10676.45720	-0.75860	29.57300	26.34440	K562	CPEB4
YARS	ENSG00000134684.6	3232.84250	5251.08770	-0.69980	4.23580	1.90130	K562	CPSF7
YARS	ENSG00000134684.6	3493.53660	5365.55380	-0.61900	6.14930	3.53120	K562	YBX3
YARS	ENSG00000134684.6	3807.82360	5166.43500	-0.44020	8.95020	6.92190	K562	CSTF2
YARS	ENSG00000134684.6	10241.07150	17671.51600	-0.78710	26.80150	24.26570	K562	CELF1
YARS	ENSG00000134684.6	3255.76950	5175.60050	-0.66870	4.78410	2.35080	K562	DDX1
YARS	ENSG00000134684.6	6334.46360	7999.73260	-0.33670	6.61680	4.70310	K562	DDX21
YARS	ENSG00000134684.6	4179.37670	6516.49830	-0.64080	12.95580	10.53720	K562	DDX3X
YARS	ENSG00000134684.6	8583.90590	11046.22970	-0.36380	8.36800	7.31560	K562	DDX47
YARS	ENSG00000134684.6	3662.03770	5498.79490	-0.58650	6.10410	4.01450	K562	DHX30
YARS	ENSG00000134684.6	2742.95150	5282.36810	-0.94550	17.10570	14.33150	K562	DNAJC21
YARS	ENSG00000134684.6	3172.75220	5599.36700	-0.81950	5.91030	3.36750	K562	DNAJC2
YARS	ENSG00000134684.6	4118.76040	6520.21970	-0.66270	6.61170	4.62770	K562	EEF2
YARS	ENSG00000134684.6	4140.32960	6299.85540	-0.60560	8.61330	6.92130	K562	EFTUD2
YARS	ENSG00000134684.6	6231.22820	7157.53000	-0.19990	2.76110	1.55430	K562	EIF2S1
YARS	ENSG00000134684.6	13949.68930	8700.31390	0.68100	24.49120	22.70370	K562	EIF2S2
YARS	ENSG00000134684.6	4682.84220	6745.30880	-0.52650	4.76110	3.36010	K562	EIF3D
YARS	ENSG00000134684.6	5363.66320	7244.37060	-0.43360	5.92280	4.77190	K562	EIF3G
YARS	ENSG00000134684.6	3290.10420	5363.30030	-0.70500	3.84320	1.47300	K562	EIF4G1
YARS	ENSG00000134684.6	7916.72870	14370.04730	-0.86010	39.80090	36.80030	K562	EIF4G2
YARS	ENSG00000134684.6	5062.74920	7886.22620	-0.63940	6.31800	3.78540	K562	ESF1
YARS	ENSG00000134684.6	6924.71960	5942.64780	0.22050	2.56780	1.32590	K562	EWSR1
YARS	ENSG00000134684.6	5408.35770	6969.10450	-0.36580	4.72990	3.02280	K562	EXOSC5
YARS	ENSG00000134684.6	3976.29410	5607.94360	-0.49600	4.35720	2.19890	K562	FAM120A
YARS	ENSG00000134684.6	4516.60120	5777.92140	-0.35530	2.95000	1.77800	K562	FKBP4
YARS	ENSG00000134684.6	3477.73250	5489.80070	-0.65860	3.57450	2.59810	K562	FMR1
YARS	ENSG00000134684.6	2600.99000	4652.79070	-0.83900	4.68940	3.47050	K562	FTO
YARS	ENSG00000134684.6	4806.66490	6316.01920	-0.39400	3.58980	1.93320	K562	GEMIN5
YARS	ENSG00000134684.6	5676.98900	8191.57770	-0.52900	4.23860	2.83710	K562	GLRX3
YARS	ENSG00000134684.6	3261.59160	5152.34850	-0.65970	3.42880	2.54710	K562	GPKOW
YARS	ENSG00000134684.6	7939.88480	11594.54510	-0.54630	6.71710	5.53150	K562	GRSF1
YARS	ENSG00000134684.6	3982.61730	6657.40400	-0.74120	15.72110	14.38210	K562	HNRNPC
YARS	ENSG00000134684.6	3609.83400	5944.52490	-0.71960	14.92120	12.27190	K562	HNRNPF
YARS	ENSG00000134684.6	7610.94770	9668.48240	-0.34520	3.02450	1.73150	K562	HNRNPK
YARS	ENSG00000134684.6	6535.13400	9983.13590	-0.61130	11.87910	9.54940	K562	HNRNPL
YARS	ENSG00000134684.6	9114.67620	6100.49890	0.57920	6.78150	5.22820	K562	HNRNPM
YARS	ENSG00000134684.6	22309.96470	10055.29660	1.14960	33.40750	31.03490	K562	HSPD1
YARS	ENSG00000134684.6	3382.52050	4960.23100	-0.55230	4.67470	2.74390	K562	KHDRBS1
YARS	ENSG00000134684.6	2270.95470	4398.68820	-0.95380	5.15070	3.82510	K562	KRR1
YARS	ENSG00000134684.6	8280.26390	6445.21470	0.36130	4.05240	2.31580	K562	LARP7
YARS	ENSG00000134684.6	2732.16710	5029.14230	-0.88030	5.23690	4.00890	K562	METAP2
YARS	ENSG00000134684.6	8354.75580	15316.63950	-0.87440	21.03090	18.27170	K562	MSI2
YARS	ENSG00000134684.6	5634.28140	8612.50800	-0.61220	8.45940	7.11830	K562	MTPAP
YARS	ENSG00000134684.6	11946.40190	15719.35160	-0.39600	5.10760	3.02940	K562	NOL12
YARS	ENSG00000134684.6	6568.68740	9568.52720	-0.54270	9.87160	8.57850	K562	NSUN2
YARS	ENSG00000134684.6	5429.24240	12540.35200	-1.20780	3.94790	2.45110	K562	PABPC1
YARS	ENSG00000134684.6	6375.44810	9052.46060	-0.50580	7.72310	6.05940	K562	PCBP2
YARS	ENSG00000134684.6	4950.36190	8864.68320	-0.84050	13.91460	12.07970	K562	PCBP3
YARS	ENSG00000134684.6	4249.18140	6799.61930	-0.67830	15.64580	13.82080	K562	POLR2G
YARS	ENSG00000134684.6	8021.80640	9885.77890	-0.30140	3.57640	2.83240	K562	PTBP1
YARS	ENSG00000134684.6	11707.06710	15678.48230	-0.42140	6.34560	5.11110	K562	PUF60
YARS	ENSG00000134684.6	10346.01590	16339.59960	-0.65930	24.45360	21.83200	K562	PUM2
YARS	ENSG00000134684.6	17852.36670	23176.35540	-0.37650	4.23740	3.58750	K562	PUS1
YARS	ENSG00000134684.6	17349.06460	22582.28720	-0.38030	7.29880	6.36650	K562	RBM15
YARS	ENSG00000134684.6	7394.75750	9477.34890	-0.35800	3.84540	2.84310	K562	RBM22
YARS	ENSG00000134684.6	7110.14430	9973.84560	-0.48830	5.78710	4.12390	K562	NELFE
YARS	ENSG00000134684.6	4720.37180	6244.63900	-0.40370	3.24020	2.35560	K562	RPS19
YARS	ENSG00000134684.6	7127.15380	9558.59900	-0.42350	3.86590	1.69710	K562	SAFB2
YARS	ENSG00000134684.6	6163.04720	9442.79900	-0.61560	11.91900	10.32710	K562	SF3A3
YARS	ENSG00000134684.6	3048.10080	4898.98970	-0.68460	3.77760	2.63320	K562	SF3B1
YARS	ENSG00000134684.6	3013.66000	5410.88380	-0.84430	13.83560	11.30430	K562	SLBP
YARS	ENSG00000134684.6	4787.16720	6121.63850	-0.35470	3.40940	1.56460	K562	SRP68
YARS	ENSG00000134684.6	5976.79820	9674.45110	-0.69480	12.39510	10.59880	K562	SRPK2
YARS	ENSG00000134684.6	7209.32500	9691.75640	-0.42690	6.73380	5.64110	K562	SRSF1
YARS	ENSG00000134684.6	5627.39590	7139.04370	-0.34330	6.43270	4.63720	K562	SRSF7
YARS	ENSG00000134684.6	7541.57420	9730.99570	-0.36770	3.86210	2.23520	K562	SSRP1
YARS	ENSG00000134684.6	5836.86050	8900.11990	-0.60860	7.84520	5.67810	K562	STAU1
YARS	ENSG00000134684.6	3100.29460	5935.72580	-0.93700	15.76400	13.36800	K562	SUPV3L1
YARS	ENSG00000134684.6	8863.61020	6820.05030	0.37800	5.84240	4.64050	K562	SYNCRIP
YARS	ENSG00000134684.6	6126.79660	9807.83400	-0.67880	10.94260	9.37730	K562	TARDBP
YARS	ENSG00000134684.6	3484.71970	5410.73700	-0.63480	7.74470	5.11150	K562	TFIP11
YARS	ENSG00000134684.6	3266.87280	5741.18020	-0.81340	13.09560	10.95460	K562	TIAL1
YARS	ENSG00000134684.6	4933.77290	6098.44590	-0.30580	2.75740	1.81450	K562	TRIM56
YARS	ENSG00000134684.6	6605.53490	8675.27060	-0.39320	4.06530	2.29360	K562	TRIP6
YARS	ENSG00000134684.6	8642.14710	10797.14300	-0.32120	7.31630	5.21910	K562	TROVE2
YARS	ENSG00000134684.6	5137.20110	6282.18800	-0.29030	2.27470	1.36020	K562	UCHL5
YARS	ENSG00000134684.6	7894.68620	10145.77120	-0.36190	4.91080	3.98420	K562	UPF1
YARS	ENSG00000134684.6	8333.22170	12511.34350	-0.58630	6.94420	5.08620	K562	UTP3
YARS	ENSG00000134684.6	6199.00960	8681.32010	-0.48590	5.15520	3.94180	K562	WDR3
YARS	ENSG00000134684.6	6608.04100	9028.22470	-0.45020	6.82140	5.54790	K562	WDR43
YARS	ENSG00000134684.6	12764.98360	15848.54900	-0.31220	3.63710	2.14510	K562	WRN
YARS	ENSG00000134684.6	4442.79870	6396.94980	-0.52590	6.31810	4.24530	K562	XRN2
YARS	ENSG00000134684.6	10429.19100	15067.14760	-0.53080	8.34220	6.71760	K562	ZC3H8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for YARS is not available on ENCORE database.

13 RBPs can affect the splicing of YARS :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239			33256762	33256855	33263363	33263444	0.13400	0.00000	0.00001	included	HepG2	HNRNPK
SE	YARS	ENSG00000134684.6	chr1	-	33252540	33252704			33251970	33252048	33256762	33256855	-0.07200	0.00000	0.00000	excluded	K562	AQR
SE	YARS	ENSG00000134684.6	chr1	-	33272082	33272238			33263363	33263444	33276191	33276367	-0.05200	0.00000	0.00000	excluded	K562	AQR
SE	YARS	ENSG00000134684.6	chr1	-	33276191	33276367			33272082	33272212	33282788	33282918	-0.10100	0.00000	0.00011	excluded	K562	SUPV3L1
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239			33252540	33252676	33263363	33263444	-0.56600	0.00000	0.00007	excluded	K562	PUS1
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239			33256762	33256855	33263363	33263444	0.18600	0.00000	0.00000	included	HepG2	HNRNPL
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239			33252540	33252676	33263363	33263444	-0.42200	0.00167	0.04992	excluded	K562	UTP18
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239			33252540	33252676	33263363	33263444	-0.44900	0.00076	0.02208	excluded	K562	RBM15
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239			33252540	33252676	33263363	33263444	-0.56300	0.00000	0.00017	excluded	K562	AGGF1
SE	YARS	ENSG00000134684.6	chr1	-	33276191	33276367			33272082	33272212	33282788	33282918	-0.11300	0.00000	0.00000	excluded	K562	HNRNPC
A3SS	YARS	ENSG00000134684.6	chr1	-	33246648	33246823			33246648	33246746	33248004	33248159	0.05300	0.00000	0.00000	longer	K562	AQR
A3SS	YARS	ENSG00000134684.6	chr1	-	33251970	33252133			33251970	33252048	33252540	33252704	0.05400	0.00000	0.00000	longer	K562	AQR
A3SS	YARS	ENSG00000134684.6	chr1	-	33244982	33245216			33244982	33245124	33245685	33245879	0.06400	0.00000	0.00000	longer	K562	AQR
A3SS	YARS	ENSG00000134684.6	chr1	-	33251962	33252183			33251962	33252048	33256762	33256855	-0.30800	0.00004	0.00035	shorter	K562	AQR
MXE	YARS	ENSG00000134684.6	chr1	-	33276191	33276367	33276511	33276658	33272082	33272212	33282788	33282918	-0.09100	0.00003	0.00153	2included	K562	DROSHA
MXE	YARS	ENSG00000134684.6	chr1	-	33263363	33263474	33272082	33272238	33252540	33252676	33276191	33276367	0.55500	0.01758	0.09924	1included	K562	AQR
MXE	YARS	ENSG00000134684.6	chr1	-	33252540	33252676	33256762	33256855	33251962	33252048	33263363	33263444	0.10800	0.00001	0.00135	1included	K562	PPIL4
MXE	YARS	ENSG00000134684.6	chr1	-	33263363	33263444	33272082	33272212	33256762	33256855	33276191	33276367	-0.08500	0.00161	0.04144	2included	K562	PPIL4
MXE	YARS	ENSG00000134684.6	chr1	-	33256762	33256855	33263016	33263239	33252540	33252676	33263363	33263444	0.05300	0.00001	0.00059	1included	HepG2	HNRNPL
MXE	YARS	ENSG00000134684.6	chr1	-	33252540	33252676	33256762	33256855	33251962	33252048	33263363	33263444	0.07700	0.00483	0.09897	1included	K562	DHX30
MXE	YARS	ENSG00000134684.6	chr1	-	33252540	33252676	33256762	33256855	33251962	33252048	33263363	33263444	-0.07300	0.00009	0.00503	2included	K562	FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

YARS

General Information

Functions

Localization

Domains (AlphaFold: YARS)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for YARS is not avaliable on ENCORE database.

44 proteins are bound to YARS RNA:

eCLIP assay for YARS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for YARS is not available on ENCORE database.

142 RBPs can affect the gene expression of YARS :

The Knockdown/knockout RNA-Seq assay for YARS is not available on ENCORE database.

13 RBPs can affect the splicing of YARS :

The Knockdown/knockout RNA-Seq assay for YARS is not avaliable on ENCORE database.