MTTP

General Information

Gene Name       : MTTP
Gene ID             : ENSG00000138823.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MTTP)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MTTPENSG00000138823.130.130.110.12ENCSR000AEF
HepG2MTTPENSG00000138823.1365.0871.0668.07ENCSR985KAT
K562MTTPENSG00000138823.130.020.030.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MTTP is not avaliable on ENCORE database.



Proteins bound to RNA
  • MTTP RNA is bound by 16 proteins.  







eCLIP assay for MTTP is not avaliable on ENCORE database.





16 proteins are bound to MTTP RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4100544491100544532+3'-UTR3.386264.25688HepG2TIAL1
chr4100503214100503249+3'-UTR,CDS3.4345912.00921HepG2BCLAF1
chr4100544586100544650+3'-UTR4.0619115.63481HepG2LIN28B
chr4100496009100496068+3'-UTR,5'-UTR,CDS,intron-Distal3.205353.74400HepG2EIF3D
chr4100544022100544076+3'-UTR3.732564.59124HepG2FUBP3
chr4100544502100544559+3'-UTR3.208865.41541HepG2GRSF1
chr4100545075100545146+3'-UTR4.245805.69494HepG2FUBP3
chr4100544633100544710+3'-UTR4.503774.49605HepG2UPF1
chr4100544236100544299+3'-UTR3.745253.06406HepG2IGF2BP1
chr4100504530100504547+3'-UTR,CDS,intron-Proximal3.436567.66871HepG2BCLAF1
chr4100534095100534164+CDS5.844328.53206HepG2SND1
chr4100510839100510906+CDS3.547214.36355HepG2LIN28B
chr4100518223100518271+CDS,intron-Proximal3.518504.76748HepG2SND1
chr4100527928100527980+CDS4.4985913.76815HepG2BCLAF1
chr4100532589100532611+CDS,intron-Proximal3.207473.27746HepG2LIN28B
chr4100534069100534095+CDS,intron-Proximal5.027284.35919HepG2SND1
chr4100543962100543997+CDS4.180443.19000HepG2SND1
chr4100534094100534179+CDS4.275117.73437HepG2RPS3
chr4100532299100532387+CDS,intron-Proximal5.063385.54337HepG2SND1
chr4100543962100543995+CDS4.361594.03377HepG2LARP4
chr4100527980100528026+CDS3.4488210.11361HepG2BCLAF1
chr4100543850100543892+CDS3.159703.03966HepG2SND1
chr4100532577100532611+CDS,intron-Proximal5.026384.94988HepG2SND1
chr4100510806100510830+CDS3.8432410.35753HepG2BCLAF1
chr4100518271100518348+CDS4.189155.79199HepG2SND1
chr4100527967100528091+CDS4.270906.64821HepG2SND1
chr4100522805100522871+CDS3.1644513.48662HepG2BCLAF1
chr4100512902100512944+CDS3.031669.95292HepG2BCLAF1
chr4100522779100522805+CDS3.119347.43909HepG2BCLAF1
chr4100512456100512508+CDS3.3996912.83321HepG2BCLAF1
chr4100543934100543993+CDS3.196115.54154HepG2LIN28B
chr4100521721100521761+CDS,intron-Proximal4.641444.65414HepG2SND1
chr4100512458100512508+CDS3.029246.27353HepG2GRWD1
chr4100530010100530073+CDS3.643003.12130HepG2YBX3
chr4100534069100534131+CDS,intron-Proximal3.791185.75355HepG2LIN28B
chr4100522808100522854+CDS3.693444.65332HepG2ZNF800
chr4100527986100528023+CDS4.998004.77100HepG2BUD13
chr4100505712100505783+intron-Distal3.651454.45128HepG2HNRNPL
chr4100525899100525970+intron-Distal3.905523.45317HepG2HNRNPL
chr4100505783100505897+intron-Distal4.131129.86969HepG2HNRNPL
chr4100512038100512093+intron-Distal3.809203.45317HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MTTP is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MTTP is not available on ENCORE database.

  • 149 RBPs can affect the levels of MTTP.  








The Knockdown/knockout RNA-Seq assay for MTTP is not available on ENCORE database.





149 RBPs can affect the gene expression of MTTP :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MTTPENSG00000138823.82141.990704044.89820-0.9172020.4384017.99060HepG2AATF
MTTPENSG00000138823.82946.183804299.07070-0.545206.032304.70070HepG2ABCF1
MTTPENSG00000138823.8891.878004200.30560-2.2356069.9780067.97670HepG2ACO1
MTTPENSG00000138823.81851.5491014730.73790-2.9920035.1122033.49550HepG2AKAP1
MTTPENSG00000138823.82658.257105010.15930-0.9144013.9073011.79230HepG2AKAP8
MTTPENSG00000138823.88955.6225012189.01440-0.444702.667401.89680HepG2ASCC1
MTTPENSG00000138823.85044.949003878.488200.379204.267102.54800HepG2ATP5C1
MTTPENSG00000138823.83637.304305469.78140-0.5886018.7355017.24680HepG2AUH
MTTPENSG00000138823.83760.454002767.772700.442104.328403.15320HepG2BCCIP
MTTPENSG00000138823.85856.912302405.301201.2838029.7554027.35470HepG2BCLAF1
MTTPENSG00000138823.82768.337101173.939601.2376020.3807018.98430HepG2BOP1
MTTPENSG00000138823.87667.738903881.318600.9822033.0792031.02120HepG2CALR
MTTPENSG00000138823.82602.750304474.89330-0.781805.811002.97640HepG2CDC40
MTTPENSG00000138823.814240.5372011580.220100.298202.144501.45760HepG2CIRBP
MTTPENSG00000138823.82314.342503925.24260-0.762206.036804.90470HepG2CNOT7
MTTPENSG00000138823.84236.456801077.665501.9748073.1479070.44370HepG2CPSF6
MTTPENSG00000138823.84350.519003539.674000.297502.776501.67060HepG2CPSF7
MTTPENSG00000138823.81790.099904782.57540-1.4177081.2693078.83150HepG2CELF1
MTTPENSG00000138823.89223.875405142.645300.8428056.9502054.50920HepG2DAZAP1
MTTPENSG00000138823.81545.749303884.38320-1.3294031.7355029.69840HepG2DDX19B
MTTPENSG00000138823.84071.002203125.551900.381203.350802.07600HepG2DDX1
MTTPENSG00000138823.88768.109404366.980101.0055032.6520029.98580HepG2DDX24
MTTPENSG00000138823.82926.613602062.023200.505106.045004.08490HepG2DDX28
MTTPENSG00000138823.89429.0049014112.14650-0.581803.734603.01840HepG2DDX3X
MTTPENSG00000138823.85473.581404059.166300.431205.181603.44540HepG2DDX47
MTTPENSG00000138823.81359.780902721.12720-1.000805.866104.79220HepG2DDX55
MTTPENSG00000138823.88293.936703922.017901.0804026.1470023.63780HepG2DDX5
MTTPENSG00000138823.83741.7902012119.76700-1.6956018.6018017.19320HepG2DDX6
MTTPENSG00000138823.86447.856002955.985301.1251032.0390029.45920HepG2DHX30
MTTPENSG00000138823.86197.051504018.386800.6249018.4046017.00940HepG2DKC1
MTTPENSG00000138823.83872.035103064.741800.337205.282204.33760HepG2DNAJC21
MTTPENSG00000138823.85302.170704109.296500.367602.402701.37530HepG2AGO1
MTTPENSG00000138823.86201.2717011653.86340-0.910207.380206.44730HepG2EIF2S1
MTTPENSG00000138823.82663.611003260.68340-0.291803.168901.91140HepG2EIF2S2
MTTPENSG00000138823.82302.753503520.03650-0.612207.067705.68260HepG2EIF3D
MTTPENSG00000138823.85641.431704213.918300.420806.236504.71040HepG2EIF3G
MTTPENSG00000138823.85862.7753012880.26140-1.135509.659808.47810HepG2EIF4A3
MTTPENSG00000138823.82691.2160012538.12250-2.2200024.7587022.86020HepG2EIF4B
MTTPENSG00000138823.88083.099605073.360700.6719025.7292023.73570HepG2EIF4G1
MTTPENSG00000138823.811024.055004859.986201.1815032.1089029.69060HepG2EIF4G2
MTTPENSG00000138823.86484.190003723.631700.8001015.0441012.82790HepG2ESF1
MTTPENSG00000138823.81291.973804340.88220-1.7484045.0940042.74450HepG2FIP1L1
MTTPENSG00000138823.83255.801002265.137200.523306.179604.36290HepG2FKBP4
MTTPENSG00000138823.83267.839201079.668701.5976012.6241010.51550HepG2FTO
MTTPENSG00000138823.810534.199707029.008300.5836011.013709.49050HepG2FUBP3
MTTPENSG00000138823.82901.830505497.27850-0.921805.863304.28770HepG2FUS
MTTPENSG00000138823.83194.4375012991.49100-2.0239022.9231021.14510HepG2FXR1
MTTPENSG00000138823.85190.4156012053.69750-1.2156010.703809.43840HepG2G3BP1
MTTPENSG00000138823.88449.8258012793.69060-0.598404.411303.27550HepG2G3BP2
MTTPENSG00000138823.82830.450904178.64620-0.562004.520303.21280HepG2GNB2L1
MTTPENSG00000138823.82151.065401221.412200.816405.877904.96840HepG2GPKOW
MTTPENSG00000138823.82582.490603633.58000-0.492603.208702.00280HepG2GRSF1
MTTPENSG00000138823.85220.656603878.666200.428603.870701.63200HepG2GRWD1
MTTPENSG00000138823.82997.196905178.76410-0.789005.055703.03330HepG2GTF2F1
MTTPENSG00000138823.84849.479204009.696700.274202.961401.95420HepG2HDGF
MTTPENSG00000138823.81556.578703318.91100-1.0923013.7548010.73500HepG2HNRNPA0
MTTPENSG00000138823.82266.564703094.10490-0.449005.687904.80550HepG2HNRNPA1
MTTPENSG00000138823.85342.227104726.140600.176702.133101.30160HepG2HNRNPA2B1
MTTPENSG00000138823.81723.747203240.99240-0.9109011.177908.31260HepG2HNRNPAB
MTTPENSG00000138823.82381.096603441.68220-0.531507.317306.23100HepG2HNRNPC
MTTPENSG00000138823.84704.639003400.011300.468403.208901.57160HepG2HNRNPD
MTTPENSG00000138823.83538.712101404.269901.3333063.9209061.45450HepG2HNRNPF
MTTPENSG00000138823.87045.6518012200.36040-0.792107.119706.03640HepG2HNRNPK
MTTPENSG00000138823.86835.524601165.634702.55180114.98790112.02270HepG2HNRNPLL
MTTPENSG00000138823.81173.222802994.61390-1.3519044.4613041.64910HepG2HNRNPM
MTTPENSG00000138823.81621.271103418.92320-1.0764051.7732049.42280HepG2HNRNPU
MTTPENSG00000138823.83107.315801382.785401.168006.653805.57430HepG2IGF2BP1
MTTPENSG00000138823.89338.8348012253.09720-0.391802.145601.54200HepG2IGF2BP2
MTTPENSG00000138823.84635.0213011495.87280-1.310508.855507.17510HepG2IGF2BP3
MTTPENSG00000138823.84658.459103839.203200.278903.340002.22020HepG2KIF1C
MTTPENSG00000138823.82245.314305121.06480-1.1895018.8577016.68980HepG2LARP4
MTTPENSG00000138823.82107.237404093.00920-0.9578013.6126011.28450HepG2LARP7
MTTPENSG00000138823.87097.255804298.791200.7232014.3051011.75310HepG2LIN28B
MTTPENSG00000138823.85993.7660012996.00800-1.1165010.214008.97790HepG2MAGOH
MTTPENSG00000138823.82468.684703466.93290-0.489904.528402.50850HepG2MARK2
MTTPENSG00000138823.83328.8657013069.42060-1.9731021.6970020.06510HepG2MATR3
MTTPENSG00000138823.81655.871403684.12680-1.1537013.9278011.73800HepG2METAP2
MTTPENSG00000138823.82400.036603512.57740-0.549506.200405.03410HepG2MSI2
MTTPENSG00000138823.84841.615701189.245302.0253020.5249018.00930HepG2MTPAP
MTTPENSG00000138823.84018.071502949.679500.445805.478303.78060HepG2NAA15
MTTPENSG00000138823.84434.2309013377.82780-1.5931016.1226014.67690HepG2NCBP2
MTTPENSG00000138823.85174.059603701.094300.483206.462904.28480HepG2NIP7
MTTPENSG00000138823.82682.280605099.42570-0.9269031.0094028.71040HepG2NOL12
MTTPENSG00000138823.86202.297201033.707402.58490131.25020127.79450HepG2NSUN2
MTTPENSG00000138823.86865.936303587.584400.936306.614105.19640HepG2PABPC1
MTTPENSG00000138823.815639.7923011916.351000.392203.141302.37460HepG2PABPC4
MTTPENSG00000138823.81582.350803384.07040-1.0967049.7383047.10530HepG2PARN
MTTPENSG00000138823.85696.3269011928.78450-1.0663069.7370067.44520HepG2PCBP1
MTTPENSG00000138823.85884.467603049.395400.9483037.1286034.71440HepG2PPIL4
MTTPENSG00000138823.810283.986503513.931101.54910124.78500121.56370HepG2PRPF4
MTTPENSG00000138823.81444.624302100.04210-0.539702.270501.53580HepG2PRPF8
MTTPENSG00000138823.83378.8101012137.65450-1.84490153.52770151.04930HepG2PTBP1
MTTPENSG00000138823.87845.668404867.791700.6885011.2776010.18420HepG2PUF60
MTTPENSG00000138823.83286.995205167.30980-0.6526032.1610030.58860HepG2PUM1
MTTPENSG00000138823.85358.725504278.189000.324805.516404.70110HepG2PUS1
MTTPENSG00000138823.810795.8960013146.08240-0.284104.360803.60210HepG2QKI
MTTPENSG00000138823.8878.318805023.28860-2.5158019.8982018.17660HepG2RAVER1
MTTPENSG00000138823.81227.702505248.87380-2.0960066.1430064.28050HepG2RBM22
MTTPENSG00000138823.83309.165704935.35940-0.576704.083802.86060HepG2RBM27
MTTPENSG00000138823.87565.262205005.788300.595704.335701.76370HepG2RBM34
MTTPENSG00000138823.82689.512403791.02620-0.495203.399101.70640HepG2RBM47
MTTPENSG00000138823.84567.6273013508.31810-1.5643095.7854093.76430HepG2NELFE
MTTPENSG00000138823.86452.1834012580.66540-0.9633049.0757047.13850HepG2RECQL
MTTPENSG00000138823.82173.777901513.036400.522705.472504.55820HepG2RPLP0
MTTPENSG00000138823.8444.941903425.03870-2.94440116.97590114.08780HepG2RPS19
MTTPENSG00000138823.82222.490204551.96410-1.034309.799908.37450HepG2RPS2
MTTPENSG00000138823.85132.699903941.268900.381002.354601.61410HepG2RPS3A
MTTPENSG00000138823.82555.230504646.29300-0.8626011.994409.78680HepG2RPS5
MTTPENSG00000138823.84504.372203044.665500.5649015.6470014.30160HepG2SAFB2
MTTPENSG00000138823.86233.386503711.398500.748008.519106.32720HepG2SART3
MTTPENSG00000138823.86370.747103744.206300.766706.259604.03410HepG2SBDS
MTTPENSG00000138823.82982.586707241.46360-1.2797020.8810018.97270HepG2SF3A3
MTTPENSG00000138823.84082.551301153.629401.8232065.6957063.02840HepG2SF3B1
MTTPENSG00000138823.85412.8354012637.45640-1.2232081.7667079.43310HepG2SF3B4
MTTPENSG00000138823.81657.531503197.79720-0.948002.780701.33050HepG2SFPQ
MTTPENSG00000138823.811677.638204667.317701.3230066.6377064.26710HepG2SLBP
MTTPENSG00000138823.81142.524503550.53230-1.63580143.05740140.06970HepG2SMN1
MTTPENSG00000138823.83450.412405116.47450-0.568403.335202.27250HepG2SMNDC1
MTTPENSG00000138823.84725.965505928.45590-0.327007.389606.67900HepG2SRFBP1
MTTPENSG00000138823.84842.725602592.043200.9016016.1382012.88870HepG2SRP68
MTTPENSG00000138823.89291.1779013190.52710-0.5056017.3039016.33560HepG2SRSF1
MTTPENSG00000138823.83265.076301379.716601.2426047.9113045.77610HepG2SRSF7
MTTPENSG00000138823.85024.4244010730.98850-1.0948072.9020070.85860HepG2SRSF9
MTTPENSG00000138823.83252.674205435.17550-0.740709.353007.21130HepG2SSRP1
MTTPENSG00000138823.84604.685702898.827100.667506.846105.01150HepG2STAU1
MTTPENSG00000138823.82255.438503428.37830-0.604105.225303.66890HepG2STIP1
MTTPENSG00000138823.83882.314905465.99130-0.4936016.1035014.80230HepG2SUCLG1
MTTPENSG00000138823.84180.229705503.47260-0.396802.588501.31040HepG2SUGP2
MTTPENSG00000138823.85466.057602930.615200.8992022.6446020.23300HepG2SUPT6H
MTTPENSG00000138823.83831.466702709.104800.500002.667502.00180HepG2SUPV3L1
MTTPENSG00000138823.816348.1368011855.490200.4635010.921109.92370HepG2TAF15
MTTPENSG00000138823.85299.345401136.678102.2209097.2821094.14350HepG2TARDBP
MTTPENSG00000138823.81151.651503321.88810-1.5283064.1427062.33770HepG2TIAL1
MTTPENSG00000138823.81945.562802797.16280-0.523804.287302.35380HepG2TROVE2
MTTPENSG00000138823.82422.998303712.97310-0.615808.651607.53480HepG2U2AF1
MTTPENSG00000138823.8493.099601600.53240-1.6986017.2497015.38910HepG2UCHL5
MTTPENSG00000138823.87472.008606422.073800.218403.121102.38790HepG2UPF1
MTTPENSG00000138823.83564.070706200.25580-0.7988038.7962036.91950HepG2UTP3
MTTPENSG00000138823.85656.244103530.189300.680006.036804.42360HepG2XPO5
MTTPENSG00000138823.82466.014405523.31470-1.163407.909006.20470HepG2XRCC6
MTTPENSG00000138823.83875.253702666.808600.539106.339105.25680HepG2XRN2
MTTPENSG00000138823.84539.996103467.693000.3886010.915009.73000HepG2ZC3H8
MTTPENSG00000138823.88171.143107063.048000.210104.733804.06730HepG2ZNF622
MTTPENSG00000138823.87764.176505016.908100.629905.606803.68520HepG2ZRANB2
MTTPENSG00000138823.814.815201.285103.527002.522901.72920K562PCBP3
MTTPENSG00000138823.812.090000.985803.616302.450701.69920K562POLR2G
MTTPENSG00000138823.80.4457013.94160-4.967203.555702.51110K562SRPK2
MTTPENSG00000138823.81.0355012.50950-3.594602.614301.76130K562WDR3
MTTPENSG00000138823.81.4783013.00990-3.137602.495801.69040K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MTTP is not available on ENCORE database.





2 RBPs can affect the splicing of MTTP :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXEMTTPENSG00000138823.8chr4+100510799100510907100512391100512508100504530100504674100512807100512947-0.167000.000000.000072includedHepG2U2AF2
MXEMTTPENSG00000138823.8chr4+100510799100510907100512391100512508100504530100504674100512807100512947-0.109000.001680.027912includedHepG2HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MTTP is not avaliable on ENCORE database.