GCSH

General Information

Gene Name       : GCSH
Gene ID             : ENSG00000140905.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GCSH)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GCSHENSG00000140905.1038.2632.4135.33ENCSR000AEF
HepG2GCSHENSG00000140905.1058.08136.2297.15ENCSR985KAT
K562GCSHENSG00000140905.1068.1773.0170.59ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GCSH is not avaliable on ENCORE database.



Proteins bound to RNA
  • GCSH RNA is bound by 7 proteins.  







eCLIP assay for GCSH is not avaliable on ENCORE database.





7 proteins are bound to GCSH RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr168112969881129747-CDS,intron-Distal5.018057.45424HepG2AQR
chr168112973581129817-CDS,intron-Distal4.733446.83552HepG2DDX3X
chr168112968481129758-CDS,intron-Distal4.7017314.00282HepG2PRPF8
chr168112981481129823-CDS,intron-Distal4.4131010.09915K562YBX3
chr168112973381129778-CDS,intron-Distal3.898813.83925K562YBX3
chr168112978081129814-CDS,intron-Distal4.6856613.81890K562YBX3
chr168112961881129744-CDS,intron-Distal3.772988.08764HepG2EFTUD2
chr168112973581129842-CDS,intron-Distal3.617933.70637K562DDX3X
chr168112942181129585-intron-Distal3.9149311.07163HepG2EFTUD2
chr168112965781129731-intron-Distal3.729704.34418HepG2RBM22
chr168112941781129550-intron-Distal4.8547812.48856HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GCSH is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GCSH is not available on ENCORE database.

  • 140 RBPs can affect the levels of GCSH.  








The Knockdown/knockout RNA-Seq assay for GCSH is not available on ENCORE database.





140 RBPs can affect the gene expression of GCSH :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GCSHENSG00000140905.5590.23490813.68440-0.463203.676502.45060HepG2AATF
GCSHENSG00000140905.5815.095501097.43400-0.429103.324402.66760HepG2ACO1
GCSHENSG00000140905.51017.554001893.09780-0.8956010.713909.73390HepG2AKAP1
GCSHENSG00000140905.5753.633701726.00650-1.1955041.3852039.27800HepG2AUH
GCSHENSG00000140905.5800.084101307.79060-0.708906.275004.83710HepG2BCCIP
GCSHENSG00000140905.5739.995201371.35130-0.8900013.5794012.39460HepG2BOP1
GCSHENSG00000140905.5669.904301005.75540-0.586305.114003.46480HepG2BUD13
GCSHENSG00000140905.51586.019001199.040200.403404.373703.42990HepG2CALR
GCSHENSG00000140905.5830.708801097.18840-0.401405.683504.79240HepG2CKAP4
GCSHENSG00000140905.51151.920101636.47750-0.506608.656007.63950HepG2CELF1
GCSHENSG00000140905.5845.095801759.82640-1.0582042.2284040.00120HepG2DAZAP1
GCSHENSG00000140905.5514.79050893.37510-0.7953011.979809.83120HepG2DDX1
GCSHENSG00000140905.5751.426501813.43680-1.2710023.0410021.41850HepG2DDX3X
GCSHENSG00000140905.5618.868301285.81320-1.0550012.9963011.47160HepG2DDX55
GCSHENSG00000140905.5990.215201429.67890-0.529902.564201.62440HepG2DDX59
GCSHENSG00000140905.51435.660101138.613200.334302.380901.44080HepG2DDX5
GCSHENSG00000140905.5597.811301557.79780-1.3817022.5689021.03250HepG2DDX6
GCSHENSG00000140905.51275.877601049.945100.281102.156301.54650HepG2DKC1
GCSHENSG00000140905.5567.61040876.02960-0.626106.763405.70190HepG2DNAJC21
GCSHENSG00000140905.5556.07020868.17820-0.642709.605508.47880HepG2DNAJC2
GCSHENSG00000140905.5788.790201497.53090-0.9249012.4379011.24060HepG2EIF2S1
GCSHENSG00000140905.51504.296901162.760200.371403.298202.11120HepG2ESF1
GCSHENSG00000140905.51584.574401072.382800.563204.976103.85870HepG2EWSR1
GCSHENSG00000140905.5466.37480718.94030-0.624404.143002.68450HepG2FAM120A
GCSHENSG00000140905.5857.108201355.20020-0.661005.513104.46160HepG2FIP1L1
GCSHENSG00000140905.5823.643101261.10630-0.614602.248401.34230HepG2FTO
GCSHENSG00000140905.51162.835001669.79030-0.522004.857903.95800HepG2FXR1
GCSHENSG00000140905.5699.086001548.96160-1.1478017.5786015.97590HepG2G3BP1
GCSHENSG00000140905.5572.69020925.44410-0.692405.924104.41390HepG2GNB2L1
GCSHENSG00000140905.51020.716801427.24290-0.483602.183201.61080HepG2GPKOW
GCSHENSG00000140905.5822.191201047.73100-0.349703.870802.72880HepG2HDGF
GCSHENSG00000140905.5281.35880485.90170-0.788305.057103.15300HepG2HNRNPA0
GCSHENSG00000140905.5873.872701161.27890-0.410205.317604.36360HepG2HNRNPF
GCSHENSG00000140905.51220.167501568.49610-0.362302.843602.13480HepG2HNRNPK
GCSHENSG00000140905.51330.402101603.13130-0.269003.971703.17500HepG2HNRNPL
GCSHENSG00000140905.5670.69580977.21540-0.543007.093906.15840HepG2HNRNPU
GCSHENSG00000140905.5912.578801143.52610-0.325502.765602.04170HepG2IGF2BP1
GCSHENSG00000140905.51248.121801574.48070-0.335102.249201.63270HepG2IGF2BP2
GCSHENSG00000140905.5817.433801003.18790-0.295403.247002.14400HepG2KIF1C
GCSHENSG00000140905.5500.07350745.31610-0.575703.333401.95880HepG2KRR1
GCSHENSG00000140905.51295.430601670.37340-0.366702.550201.91900HepG2MAGOH
GCSHENSG00000140905.5484.09270842.11480-0.798702.649001.61830HepG2METAP2
GCSHENSG00000140905.5805.908701097.12510-0.445003.753602.81460HepG2MSI2
GCSHENSG00000140905.5612.867901719.28130-1.4882028.8737026.99280HepG2NCBP2
GCSHENSG00000140905.51106.475201745.02900-0.6573012.3161010.75720HepG2NOL12
GCSHENSG00000140905.5676.402201180.62760-0.803604.445203.03910HepG2NONO
GCSHENSG00000140905.51173.439701531.11620-0.383802.741702.02330HepG2PABPC4
GCSHENSG00000140905.51220.905301521.07160-0.317103.961903.26240HepG2PCBP1
GCSHENSG00000140905.5729.89650871.60480-0.256001.933201.30870HepG2PPIL4
GCSHENSG00000140905.51054.34280735.797100.518906.288405.17410HepG2PRPF4
GCSHENSG00000140905.5665.41330991.99260-0.576104.596803.58400HepG2PRPF8
GCSHENSG00000140905.5778.731301547.73760-0.9910026.8444025.48200HepG2PTBP1
GCSHENSG00000140905.5882.584701665.72420-0.9163017.3884016.06590HepG2PUF60
GCSHENSG00000140905.51370.338701766.92220-0.366704.279303.45640HepG2PUM2
GCSHENSG00000140905.5821.784001117.80670-0.443806.403605.53580HepG2PUS1
GCSHENSG00000140905.51125.552601676.25850-0.574609.141008.10460HepG2QKI
GCSHENSG00000140905.5754.693701398.12970-0.8895017.3425015.50240HepG2RBM15
GCSHENSG00000140905.5894.606101521.30460-0.7660012.5145011.14320HepG2RBM25
GCSHENSG00000140905.51316.971801722.49130-0.387305.582504.85630HepG2NELFE
GCSHENSG00000140905.51343.785201604.25210-0.255602.781302.16290HepG2RECQL
GCSHENSG00000140905.5828.197401251.01370-0.595106.657705.66280HepG2RPLP0
GCSHENSG00000140905.5552.47500782.81630-0.502803.003602.36670HepG2RPS19
GCSHENSG00000140905.5768.60530577.011000.413502.059901.37000HepG2RPS3A
GCSHENSG00000140905.5562.83110981.29500-0.802007.497406.27940HepG2RRP9
GCSHENSG00000140905.51043.77410870.276200.262202.569001.94390HepG2SAFB2
GCSHENSG00000140905.5968.589101348.18790-0.477104.448603.57240HepG2SF3B1
GCSHENSG00000140905.51066.918301611.41180-0.5949011.7878010.70170HepG2SF3B4
GCSHENSG00000140905.5714.630301346.97910-0.914502.981701.60690HepG2SNRNP200
GCSHENSG00000140905.51023.732201870.73350-0.8698026.5467025.40820HepG2SRFBP1
GCSHENSG00000140905.51984.219001681.958000.238302.716802.24700HepG2SRSF1
GCSHENSG00000140905.5997.487901450.54300-0.540203.667102.49890HepG2SRSF3
GCSHENSG00000140905.51218.541801644.57760-0.432607.239306.29190HepG2SRSF5
GCSHENSG00000140905.5849.754301140.92550-0.425105.686704.74650HepG2SRSF7
GCSHENSG00000140905.5790.772501368.35640-0.7911019.5311018.30870HepG2SRSF9
GCSHENSG00000140905.51603.713601870.40840-0.221902.926502.29060HepG2SUCLG1
GCSHENSG00000140905.5724.45480915.36600-0.337502.334201.46500HepG2SUPT6H
GCSHENSG00000140905.5794.156301280.03380-0.688706.073205.12980HepG2SUPV3L1
GCSHENSG00000140905.51041.362701389.14970-0.415704.400403.35420HepG2TIA1
GCSHENSG00000140905.5790.62270949.69140-0.264501.957701.52170HepG2TIAL1
GCSHENSG00000140905.5762.79080958.02630-0.328803.454802.84050HepG2TRIM56
GCSHENSG00000140905.5902.050701159.46490-0.362202.350601.76720HepG2U2AF1
GCSHENSG00000140905.5543.097601569.29960-1.530806.358304.78720HepG2U2AF2
GCSHENSG00000140905.5861.957101722.32320-0.9987013.5292011.63360HepG2UBE2L3
GCSHENSG00000140905.5870.035601285.90700-0.5636010.152908.96200HepG2UPF1
GCSHENSG00000140905.51461.593701241.496100.235402.396801.83000HepG2UTP3
GCSHENSG00000140905.5578.85880726.08450-0.326901.903101.33180HepG2ZC3H8
GCSHENSG00000140905.51244.472701414.25470-0.184501.903201.42690HepG2ZNF622
GCSHENSG00000140905.5684.133301658.02460-1.2771013.1825010.65620K562ABCF1
GCSHENSG00000140905.5330.486501665.93350-2.3337016.8258015.53890K562AQR
GCSHENSG00000140905.51160.33360916.555000.340103.592702.54030K562ATP5C1
GCSHENSG00000140905.5751.29260992.61920-0.401902.937101.58180K562BCCIP
GCSHENSG00000140905.5581.03450959.32530-0.7234010.891408.98080K562BCLAF1
GCSHENSG00000140905.5323.54040905.81260-1.4853017.4565015.24300K562BOP1
GCSHENSG00000140905.5538.186001154.79620-1.101509.410806.82310K562BUD13
GCSHENSG00000140905.5620.528001008.31730-0.700408.111706.04370K562CIRBP
GCSHENSG00000140905.5508.115701490.71740-1.5528017.6618015.12890K562CNOT7
GCSHENSG00000140905.5314.10760963.16710-1.6165034.0003031.28660K562CPSF6
GCSHENSG00000140905.5558.02530727.79150-0.383202.985801.88630K562CSTF2
GCSHENSG00000140905.51554.409902647.01140-0.7680016.1947014.00240K562CELF1
GCSHENSG00000140905.5616.88040805.06510-0.384103.353902.01810K562DDX21
GCSHENSG00000140905.5477.57250664.89240-0.477404.456902.16530K562DDX24
GCSHENSG00000140905.5353.84970627.50700-0.826509.624507.55800K562DDX3X
GCSHENSG00000140905.51113.858201620.89360-0.541209.866008.72540K562DDX47
GCSHENSG00000140905.51537.09240939.921500.7095014.5905012.24600K562DKC1
GCSHENSG00000140905.5242.31220736.20490-1.603208.095806.46640K562EFTUD2
GCSHENSG00000140905.5917.496501305.53000-0.508906.018005.01830K562EIF2S2
GCSHENSG00000140905.5358.01430655.58520-0.8728010.016808.43890K562EIF4A3
GCSHENSG00000140905.5356.20300554.42050-0.638305.783703.91170K562EXOSC5
GCSHENSG00000140905.5891.409001191.70800-0.418902.945602.06990K562FIP1L1
GCSHENSG00000140905.5313.94990979.94460-1.6422032.9374030.06090K562FMR1
GCSHENSG00000140905.5301.82370830.56750-1.4604022.9088020.16800K562FTO
GCSHENSG00000140905.51022.52210681.780200.584708.178307.20680K562FXR1
GCSHENSG00000140905.51038.92150729.177500.510603.279102.49690K562G3BP2
GCSHENSG00000140905.5814.481101153.30440-0.501806.450704.75140K562GLRX3
GCSHENSG00000140905.5357.46160919.61030-1.3632024.9024022.33600K562GPKOW
GCSHENSG00000140905.51333.914901739.88070-0.383303.645702.78210K562GRSF1
GCSHENSG00000140905.5764.077301337.56810-0.807805.236502.77550K562HNRNPA0
GCSHENSG00000140905.5728.838401162.63740-0.673709.419607.56770K562HNRNPA1
GCSHENSG00000140905.5902.497801395.09890-0.628403.988002.07890K562HNRNPAB
GCSHENSG00000140905.5203.68560860.55490-2.0789030.8636028.94570K562HNRNPC
GCSHENSG00000140905.5499.00270768.33870-0.622705.919004.17080K562HNRNPF
GCSHENSG00000140905.5722.38010939.61510-0.379302.542301.36310K562HNRNPK
GCSHENSG00000140905.51148.421101464.80680-0.351103.173102.03310K562HNRNPL
GCSHENSG00000140905.5954.755501287.53490-0.431405.204003.96490K562HNRNPU
GCSHENSG00000140905.5690.36060940.87710-0.446702.780901.75290K562IGF2BP2
GCSHENSG00000140905.5905.393601360.80120-0.587802.992201.50820K562ILF2
GCSHENSG00000140905.5381.69310785.17290-1.040609.756007.88700K562KRR1
GCSHENSG00000140905.5528.90390832.92590-0.655206.693004.39770K562LARP7
GCSHENSG00000140905.5614.24250872.50530-0.506403.724901.96590K562LIN28B
GCSHENSG00000140905.5762.79500986.73130-0.371403.082802.10610K562MATR3
GCSHENSG00000140905.51299.921201038.476600.323902.995102.03920K562MBNL1
GCSHENSG00000140905.5385.06740897.63270-1.2210017.4748015.17980K562METAP2
GCSHENSG00000140905.51424.087502294.94270-0.688406.247904.56790K562MSI2
GCSHENSG00000140905.5648.985901212.55570-0.9018021.4968019.54920K562MTPAP
GCSHENSG00000140905.5362.33560654.64760-0.8534010.486308.15000K562NCBP2
GCSHENSG00000140905.5620.449301347.22160-1.1186039.8257037.57000K562NSUN2
GCSHENSG00000140905.5689.573801432.14400-1.054409.303507.02750K562PABPC1
GCSHENSG00000140905.5360.48400782.60600-1.118406.648904.91570K562PABPN1
GCSHENSG00000140905.5607.40210879.72760-0.534404.866903.55870K562PCBP2
GCSHENSG00000140905.5337.63640705.22230-1.0626011.9761010.24670K562PCBP3
GCSHENSG00000140905.5289.57310540.94720-0.901608.024006.68230K562POLR2G
GCSHENSG00000140905.5515.12530771.53920-0.582804.356303.18120K562PSIP1
GCSHENSG00000140905.51676.076702349.13600-0.487005.539704.38670K562PUF60
GCSHENSG00000140905.51940.297302448.21710-0.335504.099102.92260K562PUM2
GCSHENSG00000140905.5510.41260921.09460-0.8517011.221609.35770K562RBM22
GCSHENSG00000140905.5436.53400692.01270-0.664706.752904.57180K562RBM25
GCSHENSG00000140905.5632.84680897.92330-0.504703.969602.20570K562RBM34
GCSHENSG00000140905.5475.01650703.74470-0.567105.143203.78490K562RCC2
GCSHENSG00000140905.5735.06390969.31450-0.399102.908401.78300K562NELFE
GCSHENSG00000140905.5809.601001357.88800-0.746105.196102.97810K562SBDS
GCSHENSG00000140905.5647.412501329.41850-1.0380026.3046024.08240K562SF3A3
GCSHENSG00000140905.5303.18100874.49920-1.5283022.9346020.12370K562SF3B1
GCSHENSG00000140905.5450.62020758.58020-0.751409.627907.98440K562SF3B4
GCSHENSG00000140905.5535.57200872.61220-0.704302.921801.56680K562SFPQ
GCSHENSG00000140905.5842.952101394.95140-0.726705.343202.87910K562SMN1
GCSHENSG00000140905.5481.26900821.94090-0.772203.285001.90000K562SNRNP200
GCSHENSG00000140905.5428.87790667.15030-0.637402.321701.40040K562SRFBP1
GCSHENSG00000140905.51076.617101362.02290-0.339204.569103.39970K562SRPK2
GCSHENSG00000140905.5701.33680941.75310-0.425203.783702.96230K562SRSF1
GCSHENSG00000140905.5615.47230889.43600-0.531204.867203.40340K562SRSF5
GCSHENSG00000140905.5486.29410718.37450-0.562906.183404.42290K562SRSF7
GCSHENSG00000140905.5878.266101430.28240-0.703605.690903.82000K562STAU1
GCSHENSG00000140905.5735.585401328.96230-0.853304.424302.34840K562STIP1
GCSHENSG00000140905.5575.86230983.20070-0.771803.335601.71900K562SUPT6H
GCSHENSG00000140905.5251.21920693.95250-1.465907.492605.76170K562SUPV3L1
GCSHENSG00000140905.5742.08380542.559800.451703.937702.95630K562SYNCRIP
GCSHENSG00000140905.5495.31940953.09720-0.9443012.5826010.87960K562TARDBP
GCSHENSG00000140905.5518.31960760.39690-0.552904.560402.46790K562TBRG4
GCSHENSG00000140905.5648.07940919.37470-0.504504.931103.79060K562TIA1
GCSHENSG00000140905.5337.62640742.11410-1.1362011.682009.64620K562TIAL1
GCSHENSG00000140905.5587.79740902.22360-0.618206.119104.34310K562TRA2A
GCSHENSG00000140905.5505.12320788.19400-0.641903.914502.74890K562TRIM56
GCSHENSG00000140905.5955.693101280.50320-0.422105.694803.84180K562TROVE2
GCSHENSG00000140905.5489.83380730.26960-0.576105.915804.74270K562U2AF2
GCSHENSG00000140905.51869.279102648.38090-0.502606.361504.30830K562UBE2L3
GCSHENSG00000140905.5324.87250734.30480-1.176505.491404.01310K562UCHL5
GCSHENSG00000140905.5634.414701428.49050-1.1710038.7656036.45480K562UPF1
GCSHENSG00000140905.5576.467401222.30950-1.0843021.4491019.10140K562WDR3
GCSHENSG00000140905.5956.136901271.09260-0.410806.156004.94630K562WDR43
GCSHENSG00000140905.51039.306801877.07480-0.852904.750803.57370K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GCSH is not available on ENCORE database.





13 RBPs can affect the splicing of GCSH :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGCSHENSG00000140905.5chr16-811212058112126981118067811181998112420581124285-0.059000.000080.00404excludedHepG2SF3A3
SEGCSHENSG00000140905.5chr16-8112460181124712811242058112428581129735811299230.059000.000500.03656includedHepG2SRSF9
SEGCSHENSG00000140905.5chr16-8112460181124712811242058112428581129735811299230.151000.000000.00005includedK562HNRNPC
A3SSGCSHENSG00000140905.5chr16-8111642781116667811164278111656881118067811181990.066000.000000.00000longerK562AQR
MXEGCSHENSG00000140905.5chr16-81118067811181998112120581121269811155658111656881124205811242850.092000.001790.046441includedHepG2MATR3
MXEGCSHENSG00000140905.5chr16-81118067811181998112120581121269811155658111656881124205811242850.093000.002990.087001includedHepG2BCCIP
MXEGCSHENSG00000140905.5chr16-81118067811181998112120581121269811155658111656881124205811242850.101000.000020.000661includedHepG2SFPQ
MXEGCSHENSG00000140905.5chr16-81118067811181998112120581121269811155658111656881124205811242850.136000.000020.001221includedHepG2DDX55
MXEGCSHENSG00000140905.5chr16-81118067811181998112120581121269811155658111656881124205811242850.191000.000000.000001includedHepG2U2AF2
MXEGCSHENSG00000140905.5chr16-81118067811181998112120581121269811155658111656881124205811242850.146000.000300.031921includedK562CPSF6
MXEGCSHENSG00000140905.5chr16-81118067811181998112120581121269811155658111656881124205811242850.132000.000020.003101includedHepG2LARP4
MXEGCSHENSG00000140905.5chr16-81118067811181998112120581121269811155658111656881124205811242850.098000.001980.097801includedHepG2G3BP1
MXEGCSHENSG00000140905.5chr16-8111806781118199811212058112126981115565811165688112420581124285-0.146000.000020.007962includedHepG2SUB1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GCSH is not avaliable on ENCORE database.