SOCS3

General Information

Gene Name       : SOCS3
Gene ID             : ENSG00000184557.4
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SOCS3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SOCS3ENSG00000184557.40.250.330.29ENCSR000AEF
HepG2SOCS3ENSG00000184557.40.600.390.49ENCSR985KAT
K562SOCS3ENSG00000184557.413.998.3811.19ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SOCS3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SOCS3 RNA is bound by 3 proteins.  







eCLIP assay for SOCS3 is not avaliable on ENCORE database.





3 proteins are bound to SOCS3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr177635391976353956-3'-UTR,intron-Distal4.199433.54010K562UPF1
chr177635403376354106-3'-UTR,intron-Distal4.070685.61622K562UPF1
chr177635443976354473-3'-UTR,intron-Distal3.843633.28989K562RBM15
chr177635426976354317-3'-UTR,intron-Distal4.117853.81597K562RBM15
chr177635301776353073-3'-UTR,intron-Distal3.088585.17345K562UPF1
chr177635328176353326-3'-UTR,intron-Distal3.460413.95400K562UPF1
chr177635300276353068-3'-UTR,intron-Distal3.163065.25167K562TIA1
chr177635461176354648-CDS,intron-Distal4.325373.81597K562RBM15
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SOCS3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SOCS3 is not available on ENCORE database.

  • 142 RBPs can affect the levels of SOCS3.  








The Knockdown/knockout RNA-Seq assay for SOCS3 is not available on ENCORE database.





142 RBPs can affect the gene expression of SOCS3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SOCS3ENSG00000184557.399.5584046.581901.095703.523602.32310HepG2AATF
SOCS3ENSG00000184557.3106.7014064.758200.720302.385301.81410HepG2ACO1
SOCS3ENSG00000184557.3147.3996068.520801.105002.748902.21880HepG2AKAP1
SOCS3ENSG00000184557.3413.52400188.907201.130209.558607.76100HepG2AKAP8
SOCS3ENSG00000184557.3109.7985065.081600.754402.581501.83830HepG2AKAP8L
SOCS3ENSG00000184557.3162.7928056.679801.522006.329105.16420HepG2ASCC1
SOCS3ENSG00000184557.342.8849088.95510-1.052602.687401.30610HepG2ATP5C1
SOCS3ENSG00000184557.3150.0154097.887000.615802.132301.51580HepG2AUH
SOCS3ENSG00000184557.33.7639033.31070-3.145705.220704.43050HepG2BOP1
SOCS3ENSG00000184557.314.6239064.76720-2.146907.413906.42370HepG2CKAP4
SOCS3ENSG00000184557.343.32940239.69190-2.4678019.0262017.07850HepG2CNOT7
SOCS3ENSG00000184557.391.1829030.582501.576005.443404.50890HepG2CPSF6
SOCS3ENSG00000184557.35.8828029.62020-2.332003.595102.38430HepG2CSTF2
SOCS3ENSG00000184557.322.6380059.90270-1.403904.246903.23930HepG2DDX19B
SOCS3ENSG00000184557.389.7177051.402000.803502.074701.47780HepG2DDX21
SOCS3ENSG00000184557.394.1800047.149000.998102.402201.67590HepG2DDX55
SOCS3ENSG00000184557.326.5305061.14720-1.204602.802401.78420HepG2DDX5
SOCS3ENSG00000184557.3343.3508056.433702.6050028.4517026.78350HepG2DDX6
SOCS3ENSG00000184557.323.1693060.54340-1.385803.532702.43140HepG2DHX30
SOCS3ENSG00000184557.3181.0699076.293201.246805.830804.53390HepG2EEF2
SOCS3ENSG00000184557.3110.4937047.328101.223104.355302.95450HepG2AGO1
SOCS3ENSG00000184557.3137.8234061.933701.153904.691603.53770HepG2EIF3D
SOCS3ENSG00000184557.3175.2113058.325201.586803.474902.70730HepG2EIF4B
SOCS3ENSG00000184557.3202.6396082.235501.301008.397507.01010HepG2EIF4G2
SOCS3ENSG00000184557.320.7438085.38300-2.041307.607005.91820HepG2ESF1
SOCS3ENSG00000184557.3177.85540112.369600.662403.036602.41140HepG2ETF1
SOCS3ENSG00000184557.3197.0769099.521700.985603.876002.97740HepG2FIP1L1
SOCS3ENSG00000184557.3232.5401056.044602.0527016.8516015.27820HepG2G3BP1
SOCS3ENSG00000184557.36.6112059.57640-3.171802.460601.62270HepG2G3BP2
SOCS3ENSG00000184557.3233.6764060.125701.9584015.0797012.74180HepG2GNB2L1
SOCS3ENSG00000184557.3146.8962061.839501.248105.425304.10470HepG2HDGF
SOCS3ENSG00000184557.34.2958033.08750-2.945304.531503.74460HepG2HNRNPLL
SOCS3ENSG00000184557.326.6282070.02510-1.394904.312203.56930HepG2HNRNPU
SOCS3ENSG00000184557.3116.27610205.70250-0.823003.610202.20470HepG2HSPD1
SOCS3ENSG00000184557.34.6771029.33540-2.649003.288002.47310HepG2NSUN2
SOCS3ENSG00000184557.3158.3985055.359701.516506.833005.70590HepG2PABPC4
SOCS3ENSG00000184557.3121.9406046.277801.397707.097006.19900HepG2PCBP1
SOCS3ENSG00000184557.3141.1640053.212701.407405.625104.18580HepG2PCBP2
SOCS3ENSG00000184557.391.69140199.77490-1.123506.118103.40400HepG2PPIG
SOCS3ENSG00000184557.33.9596056.50150-3.8349012.1841010.73000HepG2PRPF4
SOCS3ENSG00000184557.3142.7201047.097601.599408.617807.76210HepG2PTBP1
SOCS3ENSG00000184557.342.0020082.36530-0.971602.608702.02740HepG2PUF60
SOCS3ENSG00000184557.348.5711087.43540-0.848102.581602.00410HepG2PUM1
SOCS3ENSG00000184557.324.6160065.96380-1.422104.325703.58710HepG2PUS1
SOCS3ENSG00000184557.3101.9984051.336500.990402.400601.74110HepG2RAVER1
SOCS3ENSG00000184557.3269.7106055.648402.2769024.8381022.72750HepG2RBM15
SOCS3ENSG00000184557.3116.0280046.283601.325805.719504.78190HepG2RBM25
SOCS3ENSG00000184557.3180.9130052.408301.787306.308905.54750HepG2NELFE
SOCS3ENSG00000184557.3137.7112048.823601.495907.923706.95940HepG2RECQL
SOCS3ENSG00000184557.38.0219050.45540-2.653006.577105.16830HepG2RPS10
SOCS3ENSG00000184557.3126.2078066.897100.915702.854801.76230HepG2RPS5
SOCS3ENSG00000184557.313.0558035.97780-1.462402.069301.38030HepG2RRP9
SOCS3ENSG00000184557.3144.31080226.77720-0.652102.777101.46530HepG2SART3
SOCS3ENSG00000184557.398.9484018.360702.430004.128503.29620HepG2SF3A3
SOCS3ENSG00000184557.3183.0211049.019901.9005011.007109.94680HepG2SF3B4
SOCS3ENSG00000184557.374.6129020.962901.831502.796601.34090HepG2SFPQ
SOCS3ENSG00000184557.329.1271078.97760-1.439104.744703.86430HepG2SLBP
SOCS3ENSG00000184557.3152.9913050.114801.610006.385104.08170HepG2SLTM
SOCS3ENSG00000184557.366.3908019.314501.781203.372901.89070HepG2SNRNP200
SOCS3ENSG00000184557.3294.3961036.441903.0140020.1015018.06380HepG2SNRNP70
SOCS3ENSG00000184557.3222.23420106.090101.066707.396406.68560HepG2SRFBP1
SOCS3ENSG00000184557.337.0146099.57950-1.427804.913601.77520HepG2SRSF4
SOCS3ENSG00000184557.3360.2334041.636503.1129040.9512039.32190HepG2SRSF9
SOCS3ENSG00000184557.3194.8131047.979302.0215011.172408.90530HepG2SUB1
SOCS3ENSG00000184557.3135.5381092.487800.551301.839601.31370HepG2SUCLG1
SOCS3ENSG00000184557.3232.9983046.935802.3115015.7939014.40820HepG2SUPV3L1
SOCS3ENSG00000184557.337.98290201.29300-2.4059013.6810011.53320HepG2TBRG4
SOCS3ENSG00000184557.3219.7349042.261302.3783019.0214016.90480HepG2TIA1
SOCS3ENSG00000184557.334.6527085.14020-1.296903.453802.75690HepG2U2AF1
SOCS3ENSG00000184557.3135.8278022.385502.601007.443105.74360HepG2U2AF2
SOCS3ENSG00000184557.370.6251016.283102.116707.774306.69920HepG2UPF1
SOCS3ENSG00000184557.355.4866015.720801.819404.616103.87430HepG2UTP3
SOCS3ENSG00000184557.314.2675046.20310-1.695303.165702.39150HepG2XRN2
SOCS3ENSG00000184557.381.9390017.908402.193809.374108.51910HepG2ZNF622
SOCS3ENSG00000184557.31049.26250822.241700.351603.730903.09000K562AGGF1
SOCS3ENSG00000184557.3709.69010501.510800.500805.545503.34290K562AKAP1
SOCS3ENSG00000184557.31288.87180903.509000.512403.353602.24790K562AKAP8
SOCS3ENSG00000184557.31332.03740855.577200.638602.735702.08660K562AKAP8L
SOCS3ENSG00000184557.3503.334501552.47950-1.6250036.2265034.31340K562AQR
SOCS3ENSG00000184557.3272.25400444.43970-0.707004.902303.72640K562BOP1
SOCS3ENSG00000184557.3354.71120608.43290-0.778507.472405.51590K562CCAR1
SOCS3ENSG00000184557.31354.69680982.632100.463105.388103.70560K562CCDC124
SOCS3ENSG00000184557.3609.56630892.41230-0.549904.059202.25760K562CKAP4
SOCS3ENSG00000184557.3625.27180911.46390-0.543702.761301.70180K562CNOT7
SOCS3ENSG00000184557.3283.08190472.57920-0.739306.588305.37320K562CPSF6
SOCS3ENSG00000184557.3368.22080664.53350-0.851807.184204.40180K562YBX3
SOCS3ENSG00000184557.31280.694202057.83760-0.6842012.6032010.60510K562CELF1
SOCS3ENSG00000184557.3463.00820964.71440-1.0591015.8618012.69130K562DDX19B
SOCS3ENSG00000184557.3686.70150520.163200.400603.324601.85990K562DDX27
SOCS3ENSG00000184557.3782.66140508.184300.622906.882305.14860K562DDX3X
SOCS3ENSG00000184557.3503.794301143.06230-1.1820032.1320030.16560K562DDX47
SOCS3ENSG00000184557.3474.61950681.16310-0.521203.710502.13080K562DHX30
SOCS3ENSG00000184557.31286.99710920.678200.483103.720202.68400K562DKC1
SOCS3ENSG00000184557.3336.58340654.26180-0.9589010.899908.49050K562DNAJC21
SOCS3ENSG00000184557.3224.12210693.51230-1.6296014.8225011.30530K562DNAJC2
SOCS3ENSG00000184557.3242.73550508.69840-1.067409.508707.23430K562EEF2
SOCS3ENSG00000184557.399.46080618.87200-2.6374031.9700029.07710K562EIF3A
SOCS3ENSG00000184557.3209.62190526.00610-1.3273010.063107.92780K562EIF3D
SOCS3ENSG00000184557.399.37770263.03140-1.4042010.273508.73310K562EIF3G
SOCS3ENSG00000184557.3208.72560530.94070-1.3469018.2449015.97350K562EIF4A3
SOCS3ENSG00000184557.3380.99840664.15640-0.801703.814401.46660K562EIF4G1
SOCS3ENSG00000184557.3515.870001673.55940-1.6978065.6203061.98300K562EIF4G2
SOCS3ENSG00000184557.3539.85540859.27110-0.670507.948705.77040K562EXOSC5
SOCS3ENSG00000184557.3260.71670476.09220-0.868807.067405.13470K562FKBP4
SOCS3ENSG00000184557.3266.68290480.81440-0.850407.380105.94850K562FMR1
SOCS3ENSG00000184557.3194.27270407.52330-1.068809.014407.27070K562FTO
SOCS3ENSG00000184557.3581.17060406.146600.516904.034202.27420K562G3BP1
SOCS3ENSG00000184557.384.54620320.75840-1.9237018.0200015.78860K562G3BP2
SOCS3ENSG00000184557.3414.410101000.13030-1.2711011.165609.01850K562GLRX3
SOCS3ENSG00000184557.3212.61250451.20660-1.0856010.165208.62760K562GPKOW
SOCS3ENSG00000184557.3484.95400817.88060-0.754004.253602.01480K562HNRNPA0
SOCS3ENSG00000184557.3606.31360964.70420-0.670005.490203.99730K562HNRNPA1
SOCS3ENSG00000184557.3228.50780548.18310-1.2624016.1834014.81940K562HNRNPC
SOCS3ENSG00000184557.3758.263401033.04530-0.446104.194902.86630K562HNRNPL
SOCS3ENSG00000184557.3246.40030432.23620-0.810806.119604.24120K562IGF2BP3
SOCS3ENSG00000184557.3295.60640832.15770-1.4932013.4026010.29740K562ILF2
SOCS3ENSG00000184557.3375.69850635.69340-0.758806.682804.39150K562ILF3
SOCS3ENSG00000184557.3318.30510614.27260-0.948509.922307.23690K562KHDRBS1
SOCS3ENSG00000184557.3192.80770429.34610-1.155007.853504.87890K562KHSRP
SOCS3ENSG00000184557.3104.99840385.24850-1.8754013.4039011.21890K562KRR1
SOCS3ENSG00000184557.3702.58050530.988700.403902.781901.38920K562LARP7
SOCS3ENSG00000184557.31135.94980869.162800.386102.828001.73820K562MAK16
SOCS3ENSG00000184557.31791.053501017.177100.8161015.1701012.79280K562MBNL1
SOCS3ENSG00000184557.3233.14370440.42390-0.917708.460806.87030K562METAP2
SOCS3ENSG00000184557.3802.876601783.83630-1.1517023.5374020.70650K562MSI2
SOCS3ENSG00000184557.3297.331601051.53570-1.8224018.0241016.21950K562MTPAP
SOCS3ENSG00000184557.3966.29860712.966700.438502.423001.61000K562NAA15
SOCS3ENSG00000184557.3374.52530530.15770-0.501403.706802.26150K562NCBP2
SOCS3ENSG00000184557.3978.149101830.61940-0.9042015.3297012.25540K562NOL12
SOCS3ENSG00000184557.3531.351001168.18700-1.1365010.186908.87830K562NSUN2
SOCS3ENSG00000184557.3524.16170875.65150-0.740304.802703.14290K562PABPC1
SOCS3ENSG00000184557.3574.73740436.533200.396702.775001.42410K562PCBP1
SOCS3ENSG00000184557.3437.509601092.99240-1.3209020.5984018.41700K562PCBP3
SOCS3ENSG00000184557.3368.69490535.23410-0.537704.108102.31350K562PHF6
SOCS3ENSG00000184557.3732.333101057.25860-0.529803.032001.39730K562PKM
SOCS3ENSG00000184557.3952.497901719.63770-0.8523017.1644014.48810K562PNPT1
SOCS3ENSG00000184557.3385.98190838.39360-1.1191019.1366017.14580K562POLR2G
SOCS3ENSG00000184557.31148.93540723.085600.668007.748606.22420K562PPIG
SOCS3ENSG00000184557.3240.80180433.77300-0.849107.956706.87190K562PTBP1
SOCS3ENSG00000184557.3918.798801825.97030-0.9908017.9569015.82010K562PUF60
SOCS3ENSG00000184557.3683.422501942.27230-1.5069050.6027047.02730K562PUM1
SOCS3ENSG00000184557.31461.943701902.97450-0.380405.072003.75480K562PUM2
SOCS3ENSG00000184557.3215.51700325.38940-0.594403.511001.58620K562RECQL
SOCS3ENSG00000184557.3188.99660486.99850-1.3656014.2776012.39690K562RPS19
SOCS3ENSG00000184557.3351.82390813.09270-1.2086010.659007.37930K562RPS3A
SOCS3ENSG00000184557.3271.80240488.82810-0.846805.765103.85970K562RRP9
SOCS3ENSG00000184557.3531.16950746.93110-0.491803.243902.07120K562SAFB
SOCS3ENSG00000184557.3410.34450772.28370-0.9123010.772208.11280K562SDAD1
SOCS3ENSG00000184557.3256.12290409.11350-0.675703.552901.76410K562SERBP1
SOCS3ENSG00000184557.3604.61220333.312700.859005.201304.00780K562SF3B4
SOCS3ENSG00000184557.3336.39880670.08630-0.9942011.840709.43590K562SLBP
SOCS3ENSG00000184557.3428.20230269.446900.668204.821402.49570K562SLTM
SOCS3ENSG00000184557.3240.31970477.66470-0.991006.641803.97780K562SRP68
SOCS3ENSG00000184557.3820.998901181.23990-0.524802.704701.77750K562SRPK2
SOCS3ENSG00000184557.3667.61630954.33140-0.515505.705503.46890K562SRSF9
SOCS3ENSG00000184557.3115.57800271.30890-1.231109.916907.45530K562SSB
SOCS3ENSG00000184557.31075.149001593.17250-0.567408.496906.07670K562SUCLG1
SOCS3ENSG00000184557.3170.51530462.81320-1.4405015.7705013.36990K562SUPV3L1
SOCS3ENSG00000184557.3431.09690840.88760-0.9639013.2257011.42670K562SYNCRIP
SOCS3ENSG00000184557.3136.75050314.84380-1.203106.611003.91110K562TAF15
SOCS3ENSG00000184557.3204.19270422.00160-1.047308.174805.43530K562TFIP11
SOCS3ENSG00000184557.3241.00590472.74930-0.972008.447706.73750K562TIAL1
SOCS3ENSG00000184557.3716.58380502.307300.512502.395701.52490K562TRIM56
SOCS3ENSG00000184557.3588.595601241.36390-1.0766022.0304018.74850K562TROVE2
SOCS3ENSG00000184557.3179.08260320.93750-0.841706.733105.48810K562U2AF2
SOCS3ENSG00000184557.31533.692502058.79570-0.424805.229903.32480K562UBE2L3
SOCS3ENSG00000184557.3320.45450489.92770-0.612404.375203.06630K562UCHL5
SOCS3ENSG00000184557.3588.153701238.66640-1.074508.855007.65870K562UPF1
SOCS3ENSG00000184557.3605.214001139.72620-0.9132010.398108.25980K562UTP3
SOCS3ENSG00000184557.3385.304801059.86660-1.4598013.9288011.91570K562WDR3
SOCS3ENSG00000184557.3566.598201102.28350-0.960107.203605.89760K562WDR43
SOCS3ENSG00000184557.31435.635201839.42260-0.357603.462702.00980K562WRN
SOCS3ENSG00000184557.3207.00460499.03630-1.2695014.2075011.18670K562XRN2
SOCS3ENSG00000184557.3528.761901748.90970-1.7258050.7102047.29180K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SOCS3 is not available on ENCORE database.






No RBPs affect the alternative splcing events of SOCS3 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for SOCS3 is not avaliable on ENCORE database.