MAT1A

General Information

Gene Name       : MAT1A
Gene ID             : ENSG00000151224.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MAT1A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAT1AENSG00000151224.120.000.000.00ENCSR000AEF
HepG2MAT1AENSG00000151224.1261.8044.6853.24ENCSR985KAT
K562MAT1AENSG00000151224.120.020.020.02ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAT1A is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAT1A RNA is bound by 19 proteins.  







eCLIP assay for MAT1A is not avaliable on ENCORE database.





19 proteins are bound to MAT1A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr108203230682032380-3'-UTR,intron-Distal,intron-Proximal4.5144015.14578HepG2UPF1
chr108203206382032124-3'-UTR,intron-Distal,intron-Proximal3.474096.27467HepG2AKAP1
chr108203328482033390-3'-UTR,intron-Distal,intron-Proximal5.125774.96498HepG2GRSF1
chr108203255182032620-3'-UTR,intron-Distal4.2014712.82020HepG2UPF1
chr108203315182033225-3'-UTR,intron-Distal6.0667429.67392HepG2UPF1
chr108203251682032536-3'-UTR,intron-Distal4.822495.41597HepG2UPF1
chr108203216182032205-3'-UTR,intron-Distal,intron-Proximal5.4260811.00768HepG2UPF1
chr108203207682032107-3'-UTR,intron-Distal,intron-Proximal3.506895.45714HepG2UPF1
chr108203255582032627-3'-UTR,intron-Distal3.435098.46839HepG2AKAP1
chr108203238482032491-3'-UTR,intron-Distal,intron-Proximal5.4583023.63796HepG2UPF1
chr108203303682033109-3'-UTR,intron-Distal3.232764.17347HepG2FAM120A
chr108203187382031949-3'-UTR,intron-Distal4.9380515.60584HepG2UPF1
chr108203198982032063-3'-UTR,intron-Distal4.4100411.25346HepG2AKAP1
chr108203281482032844-3'-UTR,intron-Distal3.697073.92922HepG2AKAP1
chr108203335182033386-3'-UTR,intron-Distal5.112187.45692HepG2UPF1
chr108203241282032472-3'-UTR,intron-Distal,intron-Proximal4.268435.37876HepG2AKAP1
chr108203305982033166-3'-UTR,intron-Distal5.4333216.62638HepG2AKAP1
chr108203322882033328-3'-UTR,intron-Distal,intron-Proximal5.6583522.23925HepG2AKAP1
chr108203304182033151-3'-UTR,intron-Distal5.6791733.09850HepG2UPF1
chr108203269882032743-3'-UTR,intron-Distal3.360664.25624HepG2AKAP1
chr108203322582033287-3'-UTR,intron-Distal,intron-Proximal5.0596720.39686HepG2UPF1
chr108203316682033220-3'-UTR,intron-Distal4.3272213.22641HepG2AKAP1
chr108203281782032831-3'-UTR,intron-Distal4.735266.96152HepG2UPF1
chr108203318982033248-3'-UTR,intron-Distal,intron-Proximal3.780833.06084HepG2HNRNPK
chr108203199082032070-3'-UTR,intron-Distal4.6287615.64942HepG2UPF1
chr108203228482032381-3'-UTR,intron-Distal,intron-Proximal4.5589712.27244HepG2AKAP1
chr108204922182049291-5'-UTR,intron-Distal5.7425910.81699HepG2BCLAF1
chr108204910082049215-5'-UTR,CDS,intron-Distal,intron-Proximal3.376755.02357HepG2FXR2
chr108204908582049221-5'-UTR,CDS,intron-Distal,intron-Proximal5.1725038.47991HepG2BCLAF1
chr108204919382049354-5'-UTR,intron-Distal,intron-Proximal3.208034.54015HepG2TRA2A
chr108204923082049342-5'-UTR,intron-Distal3.022225.18088HepG2GRWD1
chr108204913382049230-5'-UTR,CDS,intron-Distal,intron-Proximal5.5169216.26652HepG2GRWD1
chr108204908682049249-5'-UTR,CDS,intron-Distal,intron-Proximal5.050016.64835HepG2UCHL5
chr108204522882045388-CDS,intron-Distal,intron-Proximal4.759609.33787HepG2AQR
chr108204044182040464-CDS,intron-Distal3.153734.02291HepG2GRWD1
chr108203472382034824-CDS,intron-Distal,intron-Proximal4.6150020.98117HepG2PRPF8
chr108204531982045345-CDS,intron-Distal4.187475.74979HepG2GRWD1
chr108204532682045347-CDS,intron-Distal,intron-Proximal4.347414.50440HepG2PPIG
chr108203623282036269-CDS,intron-Distal,intron-Proximal3.303564.24070HepG2GRWD1
chr108204377082043914-CDS,intron-Distal,intron-Proximal4.068773.31322HepG2SF3B4
chr108204908382049131-CDS,intron-Distal,intron-Proximal4.243213.85588HepG2ZNF800
chr108204908682049133-CDS,intron-Distal,intron-Proximal4.6137011.82039HepG2GRWD1
chr108204373382043787-CDS,intron-Distal4.376634.83675HepG2G3BP1
chr108204907982049128-CDS,intron-Distal,intron-Proximal3.711817.72793HepG2PPIG
chr108204907982049128-CDS,intron-Distal,intron-Proximal3.789197.10322HepG2BUD13
chr108203608882036184-CDS,intron-Distal,intron-Proximal4.700765.90930HepG2AQR
chr108204527082045369-CDS,intron-Distal,intron-Proximal3.4615911.64842HepG2BUD13
chr108204006982040136-CDS,intron-Distal,intron-Proximal4.781985.59044HepG2SF3B4
chr108203492882034973-CDS,intron-Distal,intron-Proximal3.066614.05586HepG2U2AF2
chr108204527182045331-CDS,intron-Distal3.054703.16615HepG2G3BP1
chr108203490382034944-CDS,intron-Distal3.245423.77614HepG2G3BP1
chr108204526682045319-CDS,intron-Distal,intron-Proximal3.159533.99689HepG2GRWD1
chr108203447582034531-intron-Distal,intron-Proximal3.308823.51682HepG2RBFOX2
chr108203496082035007-intron-Distal,intron-Proximal3.955943.56713HepG2SF3B4
chr108203900282039164-intron-Distal3.976996.99640HepG2HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAT1A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAT1A is not available on ENCORE database.

  • 142 RBPs can affect the levels of MAT1A.  








The Knockdown/knockout RNA-Seq assay for MAT1A is not available on ENCORE database.





142 RBPs can affect the gene expression of MAT1A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAT1AENSG00000151224.81052.046101622.00960-0.624604.175002.10390HepG2AARS
MAT1AENSG00000151224.8814.417401430.33490-0.8125012.0625010.05690HepG2AATF
MAT1AENSG00000151224.85551.936301977.136301.4895040.8199038.18820HepG2ABCF1
MAT1AENSG00000151224.8554.959401967.47370-1.82590104.67120102.35410HepG2ACO1
MAT1AENSG00000151224.81385.70750976.389400.505004.192802.99330HepG2ADAR
MAT1AENSG00000151224.8577.251703686.36950-2.6749086.1058083.85350HepG2AKAP1
MAT1AENSG00000151224.81097.212001917.25890-0.805204.779803.42490HepG2AKAP8
MAT1AENSG00000151224.81620.930401976.56750-0.286203.670702.79920HepG2AKAP8L
MAT1AENSG00000151224.81661.70710818.090901.022205.567003.08990HepG2APOBEC3C
MAT1AENSG00000151224.81509.441502712.74910-0.8457028.1630026.38600HepG2AUH
MAT1AENSG00000151224.8682.859801654.90530-1.277109.877308.05260HepG2BCCIP
MAT1AENSG00000151224.82488.017901437.752200.791105.216404.01720HepG2BCLAF1
MAT1AENSG00000151224.81042.59010804.485400.373902.753002.15600HepG2BOP1
MAT1AENSG00000151224.8567.031001172.53210-1.0481020.1556018.42660HepG2CALR
MAT1AENSG00000151224.85755.809202897.813000.9900019.8810018.03060HepG2CIRBP
MAT1AENSG00000151224.8511.15470876.15670-0.777403.119102.30370HepG2CNOT7
MAT1AENSG00000151224.81109.13840738.543900.586605.671804.71990HepG2CPSF6
MAT1AENSG00000151224.81633.984201001.289500.7064014.2578012.09050HepG2YBX3
MAT1AENSG00000151224.81054.547201464.92260-0.474202.941301.52790HepG2CSTF2T
MAT1AENSG00000151224.8958.550001837.41570-0.9388025.6183024.06840HepG2CELF1
MAT1AENSG00000151224.84230.520701819.548401.2172077.9163075.19020HepG2DDX19B
MAT1AENSG00000151224.83172.947601577.092301.0085023.0924021.39480HepG2DDX21
MAT1AENSG00000151224.82300.566701544.135800.575108.988407.36990HepG2DDX24
MAT1AENSG00000151224.84159.008101522.243801.4499025.2602022.12070HepG2DDX27
MAT1AENSG00000151224.82012.351503531.09120-0.8112011.8136010.60430HepG2DDX3X
MAT1AENSG00000151224.8803.993101051.09130-0.386603.363601.86770HepG2DDX52
MAT1AENSG00000151224.8802.541901627.23590-1.019808.678107.39160HepG2DDX55
MAT1AENSG00000151224.83329.798901372.815701.2782031.4119028.77390HepG2DDX5
MAT1AENSG00000151224.81311.040403033.68520-1.2104020.4725019.00010HepG2DDX6
MAT1AENSG00000151224.81627.16160948.262500.7789012.1888010.32920HepG2DHX30
MAT1AENSG00000151224.86839.718701882.292501.86130163.73720160.99960HepG2DKC1
MAT1AENSG00000151224.8492.70790983.15150-0.9967020.0629018.35040HepG2DNAJC21
MAT1AENSG00000151224.81679.16420974.527700.7849024.8803023.11070HepG2DNAJC2
MAT1AENSG00000151224.82452.282801253.952900.9675014.0641012.23500HepG2EEF2
MAT1AENSG00000151224.81294.377602915.95340-1.1717022.4095020.83040HepG2EIF2S1
MAT1AENSG00000151224.8715.590101017.85650-0.508304.188903.09270HepG2EIF3D
MAT1AENSG00000151224.82180.466301489.862500.549408.298406.62030HepG2EIF3G
MAT1AENSG00000151224.85229.339303222.277000.698408.174907.07940HepG2EIF4A3
MAT1AENSG00000151224.81847.456303137.70980-0.764207.267606.18190HepG2EIF4B
MAT1AENSG00000151224.83165.691701949.092700.6996022.3330020.44830HepG2EIF4G1
MAT1AENSG00000151224.82866.615801867.068900.618508.653107.24310HepG2EIF4G2
MAT1AENSG00000151224.82454.139001712.529000.519005.713904.19970HepG2ESF1
MAT1AENSG00000151224.82022.684103114.61010-0.6228017.5551016.25430HepG2ETF1
MAT1AENSG00000151224.8639.70710909.85690-0.508205.539203.85020HepG2FAM120A
MAT1AENSG00000151224.81092.461901503.34850-0.460604.884303.42800HepG2FASTKD2
MAT1AENSG00000151224.8629.000201996.37710-1.6663032.9579030.86760HepG2FIP1L1
MAT1AENSG00000151224.81880.044601354.284800.473103.254001.87940HepG2FKBP4
MAT1AENSG00000151224.82531.714901848.319900.453803.772801.83490HepG2FMR1
MAT1AENSG00000151224.81235.30800739.846300.739503.058601.98940HepG2FTO
MAT1AENSG00000151224.81334.496001948.83300-0.546307.173305.94510HepG2FUBP3
MAT1AENSG00000151224.81156.935201679.02910-0.537303.520502.26010HepG2FUS
MAT1AENSG00000151224.8633.529203251.73050-2.3597082.1472079.11390HepG2FXR1
MAT1AENSG00000151224.8871.741203016.14750-1.7907045.4189042.88100HepG2G3BP1
MAT1AENSG00000151224.84751.607403202.431400.569107.002405.57240HepG2G3BP2
MAT1AENSG00000151224.81329.01540906.247900.552305.266604.02590HepG2GEMIN5
MAT1AENSG00000151224.85220.41500837.149102.6405098.4259095.46640HepG2GPKOW
MAT1AENSG00000151224.8499.56370810.91730-0.698902.827801.70210HepG2GRSF1
MAT1AENSG00000151224.8847.692601583.02680-0.901107.771905.34460HepG2GTF2F1
MAT1AENSG00000151224.81409.680101878.26480-0.414007.067405.59520HepG2HDGF
MAT1AENSG00000151224.81629.94160992.571000.7155010.612509.47030HepG2HNRNPA1
MAT1AENSG00000151224.81389.731601815.59530-0.385605.343204.11840HepG2HNRNPA2B1
MAT1AENSG00000151224.82748.966701274.438101.1089044.1175041.90220HepG2HNRNPF
MAT1AENSG00000151224.81184.993103054.84480-1.3662035.5799033.37320HepG2HNRNPK
MAT1AENSG00000151224.81468.249201799.39540-0.293404.248303.42640HepG2HNRNPL
MAT1AENSG00000151224.81700.13240798.911201.0894018.5390017.12240HepG2HNRNPLL
MAT1AENSG00000151224.8641.141001377.25910-1.1031023.2496021.02090HepG2HNRNPM
MAT1AENSG00000151224.81405.295202086.79160-0.570403.076101.76960HepG2HSPD1
MAT1AENSG00000151224.84678.533201254.947701.8983095.7266092.66480HepG2IGF2BP1
MAT1AENSG00000151224.83879.535203065.737900.339502.808802.12890HepG2IGF2BP2
MAT1AENSG00000151224.8407.097702877.50600-2.8214028.6982025.97640HepG2IGF2BP3
MAT1AENSG00000151224.8879.940901120.31100-0.348404.733103.79610HepG2ILF2
MAT1AENSG00000151224.81716.562901321.738300.377002.238501.49920HepG2LARP4
MAT1AENSG00000151224.8954.710001484.00680-0.636404.590103.12580HepG2LARP7
MAT1AENSG00000151224.8983.699801557.57980-0.663005.403903.70820HepG2LIN28B
MAT1AENSG00000151224.88195.433803252.868301.3330032.6601030.61000HepG2MAGOH
MAT1AENSG00000151224.8798.661901256.09220-0.653304.995702.87530HepG2MARK2
MAT1AENSG00000151224.82202.787103270.97860-0.570405.615904.74260HepG2MATR3
MAT1AENSG00000151224.8509.467901065.22650-1.064108.655506.89990HepG2METAP2
MAT1AENSG00000151224.8864.362601615.49030-0.9023017.0697015.26130HepG2MSI2
MAT1AENSG00000151224.81433.01310814.890400.814306.658705.11790HepG2MTPAP
MAT1AENSG00000151224.81087.099001356.59220-0.319502.619401.43690HepG2NAA15
MAT1AENSG00000151224.82182.919601341.741800.702109.270506.77390HepG2NIP7
MAT1AENSG00000151224.81385.857201958.84810-0.499207.284306.06040HepG2NOL12
MAT1AENSG00000151224.82046.97940708.422401.5307038.9502036.68830HepG2NSUN2
MAT1AENSG00000151224.8439.11450800.55770-0.866402.498901.66360HepG2PABPC1
MAT1AENSG00000151224.82082.149002981.21120-0.517805.137304.16640HepG2PABPC4
MAT1AENSG00000151224.8434.455001085.59060-1.3212037.2437034.84670HepG2PARN
MAT1AENSG00000151224.83688.365803152.198500.226502.188101.63800HepG2PCBP1
MAT1AENSG00000151224.82230.594301589.305500.488902.985701.90800HepG2PCBP2
MAT1AENSG00000151224.81226.31230978.227900.326003.336902.53390HepG2PPIL4
MAT1AENSG00000151224.81778.702301414.572800.330402.663701.90330HepG2PRPF4
MAT1AENSG00000151224.8838.641101254.63520-0.581104.969203.92160HepG2PRPF8
MAT1AENSG00000151224.82558.853403207.34590-0.325905.607304.88390HepG2PTBP1
MAT1AENSG00000151224.84490.371401869.958501.2637040.5318038.57950HepG2PUF60
MAT1AENSG00000151224.8961.640501983.62290-1.0446026.1315024.20320HepG2PUM2
MAT1AENSG00000151224.84517.611502003.973201.1726073.0809070.84730HepG2PUS1
MAT1AENSG00000151224.82719.073903473.92030-0.353403.270702.59970HepG2QKI
MAT1AENSG00000151224.8598.426301533.29680-1.3574013.3584011.91820HepG2RAVER1
MAT1AENSG00000151224.81308.179101736.01990-0.408204.624303.55090HepG2RBM15
MAT1AENSG00000151224.8707.101102603.23540-1.8803096.3541094.16790HepG2RBM22
MAT1AENSG00000151224.81972.100303152.69810-0.6769012.8186011.42800HepG2RBM25
MAT1AENSG00000151224.81248.951801789.54770-0.518903.145002.08390HepG2RBM27
MAT1AENSG00000151224.8440.67550845.96020-0.940903.922602.10210HepG2RBM47
MAT1AENSG00000151224.82648.677101453.199100.8659011.506809.38920HepG2RCC2
MAT1AENSG00000151224.82904.160203569.57930-0.297602.410401.89930HepG2NELFE
MAT1AENSG00000151224.83493.111901373.032101.3470037.5634035.72170HepG2RPLP0
MAT1AENSG00000151224.83101.511701506.931301.0413011.185809.41850HepG2RPS10
MAT1AENSG00000151224.8810.11790990.49520-0.290002.096501.55470HepG2RPS19
MAT1AENSG00000151224.82739.15370879.028601.6396029.0755026.61530HepG2RPS3A
MAT1AENSG00000151224.81284.504101684.74570-0.391302.392101.39790HepG2RPS5
MAT1AENSG00000151224.8743.797901241.03050-0.738606.890605.71260HepG2RRP9
MAT1AENSG00000151224.81286.70330976.710900.397602.190901.60590HepG2SAFB2
MAT1AENSG00000151224.81518.41130993.996100.611206.673705.22160HepG2SERBP1
MAT1AENSG00000151224.81651.611202666.20810-0.690906.200005.16700HepG2SF3A3
MAT1AENSG00000151224.82251.35840790.736501.5094040.5582038.27110HepG2SF3B1
MAT1AENSG00000151224.82029.438703339.50130-0.7186017.0070015.73060HepG2SF3B4
MAT1AENSG00000151224.82909.636101793.158500.6982027.4122025.65220HepG2SLBP
MAT1AENSG00000151224.8586.447901138.99100-0.9577026.8994025.22960HepG2SMN1
MAT1AENSG00000151224.8663.401002940.25450-2.14800164.55140162.24440HepG2SRFBP1
MAT1AENSG00000151224.84142.152303485.618300.248902.546602.08780HepG2SRSF1
MAT1AENSG00000151224.81584.382401846.40490-0.220802.109301.55430HepG2SRSF5
MAT1AENSG00000151224.82618.644301252.128001.0643019.5507018.00720HepG2SRSF7
MAT1AENSG00000151224.82059.260902835.65170-0.4616010.542609.58800HepG2SRSF9
MAT1AENSG00000151224.88237.083302552.829901.68990159.93100157.71930HepG2SSB
MAT1AENSG00000151224.81393.384602080.03960-0.578003.040101.69640HepG2SSRP1
MAT1AENSG00000151224.8507.24110764.39610-0.591602.507701.46850HepG2STIP1
MAT1AENSG00000151224.81607.848402099.79120-0.385106.694805.80110HepG2SUCLG1
MAT1AENSG00000151224.81435.78490778.818300.8824013.2483011.84810HepG2TARDBP
MAT1AENSG00000151224.81419.093002878.84770-1.0205018.0351015.96720HepG2TIA1
MAT1AENSG00000151224.82835.538101065.645101.4118053.2407051.57380HepG2TIAL1
MAT1AENSG00000151224.8759.614601075.24840-0.501307.473406.62350HepG2TRIM56
MAT1AENSG00000151224.82337.701401707.630300.453004.411803.62720HepG2U2AF1
MAT1AENSG00000151224.8339.20400956.67920-1.4959015.3444013.59540HepG2UCHL5
MAT1AENSG00000151224.83164.464202364.510400.420309.527508.36610HepG2UPF1
MAT1AENSG00000151224.8759.160801508.49900-0.990609.527807.29330HepG2XRCC5
MAT1AENSG00000151224.8971.778001686.62960-0.795406.970105.35380HepG2XRCC6
MAT1AENSG00000151224.82735.798301594.423700.778809.045907.75310HepG2XRN2
MAT1AENSG00000151224.82167.349001396.054700.6345018.3038016.84330HepG2ZC3H8
MAT1AENSG00000151224.81477.697202600.52090-0.8154027.0929025.82970HepG2ZNF622
MAT1AENSG00000151224.833.636707.191402.225603.308002.67770K562AQR
MAT1AENSG00000151224.819.888203.790402.391402.257001.31680K562CNOT7
MAT1AENSG00000151224.813.424400.504104.735002.864601.41250K562GEMIN5
MAT1AENSG00000151224.851.972003.089704.072108.806007.43860K562GRSF1
MAT1AENSG00000151224.842.781004.664703.197007.884606.15060K562HNRNPA1
MAT1AENSG00000151224.854.182005.084703.413508.703207.69440K562HNRNPC
MAT1AENSG00000151224.813.759000.499404.783903.066101.68360K562NONO
MAT1AENSG00000151224.816.927002.997402.497402.503601.82780K562TARDBP
MAT1AENSG00000151224.839.863008.102702.298504.442003.30800K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAT1A is not available on ENCORE database.





3 RBPs can affect the splicing of MAT1A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMAT1AENSG00000151224.8chr10-820436718204379482040435820405488204526782045345-0.241000.000050.00166excludedHepG2U2AF1
SEMAT1AENSG00000151224.8chr10-820436718204379482040435820405488204526782045345-0.313000.000000.00000excludedHepG2HNRNPK
SEMAT1AENSG00000151224.8chr10-820436718204379482040435820405488204526782045345-0.231000.000000.00001excludedHepG2PCBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAT1A is not avaliable on ENCORE database.