FHL2

General Information

Gene Name       : FHL2
Gene ID             : ENSG00000115641.18
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: FHL2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FHL2ENSG00000115641.181.561.821.69ENCSR000AEF
HepG2FHL2ENSG00000115641.1813.8212.8813.35ENCSR985KAT
K562FHL2ENSG00000115641.1822.6322.2722.45ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FHL2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FHL2 RNA is bound by 11 proteins.  







eCLIP assay for FHL2 is not avaliable on ENCORE database.





11 proteins are bound to FHL2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2105984104105984147-3'-UTR,CDS,intron-Distal3.357583.87559K562YBX3
chr2105977540105977609-3'-UTR,intron-Distal4.3489610.38725HepG2SUB1
chr2105977526105977593-3'-UTR,intron-Distal3.282284.00685K562TIA1
chr2105977484105977508-3'-UTR,intron-Distal3.565524.31744K562YBX3
chr2105977593105977681-3'-UTR,intron-Distal4.2314011.02703K562TIA1
chr2106002864106002998-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.275524.10374K562DDX3X
chr2106002753106002818-3'-UTR,CDS,intron-Distal,intron-Proximal5.116075.26064K562AQR
chr2105984024105984101-3'-UTR,CDS,intron-Distal,intron-Proximal4.036158.72318K562YBX3
chr2105979887105979931-3'-UTR,CDS,intron-Distal,intron-Proximal4.099084.55095K562YBX3
chr2105979781105979815-3'-UTR,CDS,intron-Distal3.527455.15600K562LIN28B
chr2106015329106015399-5'-UTR,CDS,intron-Distal3.202893.24636K562DDX3X
chr2106002778106002924-5'-UTR,CDS,intron-Distal,intron-Proximal3.849623.15006K562RBM15
chr2106015399106015467-5'-UTR,CDS,intron-Distal4.437633.86664K562DDX3X
chr2106002817106002890-5'-UTR,CDS,intron-Distal,intron-Proximal3.463184.93097K562YBX3
chr2105991456105991546-intron-Distal4.609586.76436K562HNRNPL
chr2106009096106009212-intron-Distal4.719103.74583HepG2PTBP1
chr2105991440105991524-intron-Distal3.218855.13388HepG2HNRNPL
chr2106015085106015145-intron-Distal4.297133.69238K562GTF2F1
chr2106015079106015180-intron-Distal4.998657.34038HepG2PRPF4
chr2106010982106011042-intron-Distal3.833343.09122HepG2PTBP1
chr2105991602105991683-intron-Distal3.980826.35227HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FHL2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FHL2 is not available on ENCORE database.

  • 137 RBPs can affect the levels of FHL2.  








The Knockdown/knockout RNA-Seq assay for FHL2 is not available on ENCORE database.





137 RBPs can affect the gene expression of FHL2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FHL2ENSG00000115641.14701.73350312.446301.1672024.0149022.62390HepG2ACO1
FHL2ENSG00000115641.14178.66840434.42590-1.2818013.7793011.81360HepG2ADAR
FHL2ENSG00000115641.14318.66660763.58070-1.260706.303305.53760HepG2AKAP1
FHL2ENSG00000115641.14707.54560429.938700.718605.659704.19520HepG2AKAP8
FHL2ENSG00000115641.14435.37940313.929000.471703.555502.69910HepG2AKAP8L
FHL2ENSG00000115641.141057.65810631.742500.743407.612106.34030HepG2ASCC1
FHL2ENSG00000115641.14744.20070450.749100.723309.170308.04030HepG2AUH
FHL2ENSG00000115641.14197.23130333.84990-0.759304.560903.35640HepG2BCCIP
FHL2ENSG00000115641.14221.82690517.00290-1.2207010.828308.94070HepG2CCAR1
FHL2ENSG00000115641.14171.51720600.21710-1.8071012.7826011.25370HepG2CIRBP
FHL2ENSG00000115641.14206.25430312.39610-0.599004.369703.57020HepG2CKAP4
FHL2ENSG00000115641.14688.210201571.14260-1.190903.147402.32810HepG2CNOT7
FHL2ENSG00000115641.1434.1215095.03340-1.477804.895204.00320HepG2CPSF6
FHL2ENSG00000115641.14480.76470224.283401.099905.970904.38730HepG2CPSF7
FHL2ENSG00000115641.14586.97200445.488400.397802.991101.93060HepG2YBX3
FHL2ENSG00000115641.1495.54150206.15030-1.109507.091305.48450HepG2CSTF2
FHL2ENSG00000115641.142039.46180661.784301.6237056.0366053.90970HepG2CELF1
FHL2ENSG00000115641.14181.00700288.97620-0.674905.359804.25030HepG2DDX19B
FHL2ENSG00000115641.14636.81610446.128500.513304.621603.14470HepG2DDX1
FHL2ENSG00000115641.14141.23410517.38740-1.8732029.7674027.89270HepG2DDX21
FHL2ENSG00000115641.14228.02760506.52290-1.1514013.9529011.98390HepG2DDX24
FHL2ENSG00000115641.14124.54100248.58830-0.997106.339704.35540HepG2DDX28
FHL2ENSG00000115641.14537.69060731.33140-0.443701.865301.34120HepG2DDX3X
FHL2ENSG00000115641.141217.94250328.267901.8914032.0120029.84340HepG2DDX55
FHL2ENSG00000115641.14371.96610107.917301.785104.159302.97350HepG2DDX59
FHL2ENSG00000115641.142599.68890628.514002.0482041.2722039.31060HepG2DDX6
FHL2ENSG00000115641.14272.49190421.92330-0.630804.523103.28280HepG2DHX30
FHL2ENSG00000115641.1452.47460298.93100-2.5101033.2319031.55980HepG2DKC1
FHL2ENSG00000115641.14611.46420437.462500.483004.359503.49330HepG2DNAJC21
FHL2ENSG00000115641.14124.14320411.57750-1.7292019.6351017.54440HepG2EEF2
FHL2ENSG00000115641.14171.07590488.73530-1.5144022.1560019.72940HepG2EIF3G
FHL2ENSG00000115641.14264.91970413.47020-0.642203.717801.67320HepG2EIF3H
FHL2ENSG00000115641.1479.11260667.26860-3.0763025.1253023.24650HepG2EIF4A3
FHL2ENSG00000115641.14481.63710672.46240-0.481503.250402.37160HepG2EIF4G2
FHL2ENSG00000115641.1475.70730236.02280-1.640404.258402.93070HepG2ESF1
FHL2ENSG00000115641.14274.52900517.47120-0.914507.734106.81500HepG2ETF1
FHL2ENSG00000115641.14518.59190298.655400.796008.251206.20700HepG2FAM120A
FHL2ENSG00000115641.14678.05710493.167100.459203.545602.27510HepG2FASTKD2
FHL2ENSG00000115641.14221.97070354.45600-0.675204.658103.65460HepG2FUBP3
FHL2ENSG00000115641.14453.92490673.66040-0.569601.992201.40110HepG2FXR1
FHL2ENSG00000115641.14341.53120624.70090-0.871103.925003.13920HepG2G3BP1
FHL2ENSG00000115641.14276.89060663.48480-1.260707.568806.08230HepG2G3BP2
FHL2ENSG00000115641.14106.79240297.43220-1.4778013.4666011.60730HepG2GEMIN5
FHL2ENSG00000115641.1434.10890107.72900-1.659206.194705.26280HepG2GPKOW
FHL2ENSG00000115641.14519.105301454.74820-1.486705.139403.61620HepG2GRSF1
FHL2ENSG00000115641.14474.32880298.307500.669007.182905.70030HepG2HDGF
FHL2ENSG00000115641.14267.91420524.95090-0.970405.840103.74600HepG2HLTF
FHL2ENSG00000115641.1431.92150441.65300-3.7903061.4705059.27030HepG2HNRNPA1
FHL2ENSG00000115641.141109.14180653.921700.7622015.0286013.20650HepG2HNRNPA2B1
FHL2ENSG00000115641.14190.37440491.24470-1.3676015.8414014.31750HepG2HNRNPC
FHL2ENSG00000115641.14293.78090487.99780-0.732108.322307.31100HepG2HNRNPU
FHL2ENSG00000115641.14239.65360468.20070-0.966207.350805.39250HepG2HSPD1
FHL2ENSG00000115641.14393.97880634.91720-0.688503.676702.90690HepG2IGF2BP2
FHL2ENSG00000115641.14769.77350498.475800.626804.367503.46600HepG2ILF2
FHL2ENSG00000115641.14662.364801498.83160-1.178103.871402.42010HepG2KHDRBS1
FHL2ENSG00000115641.14579.52760416.295100.477203.079901.34020HepG2CCAR2
FHL2ENSG00000115641.14386.71700285.626100.437103.164902.07670HepG2KIF1C
FHL2ENSG00000115641.14239.55430467.80180-0.965506.596104.68060HepG2KRR1
FHL2ENSG00000115641.14323.02840546.13110-0.757605.050903.91610HepG2LARP4
FHL2ENSG00000115641.14192.68160483.81390-1.3282015.8290013.18180HepG2LIN28B
FHL2ENSG00000115641.14298.74800462.26560-0.629803.813701.81220HepG2LSM11
FHL2ENSG00000115641.1483.55940673.89740-3.0117022.5446020.77350HepG2MAGOH
FHL2ENSG00000115641.14381.83490677.60180-0.827504.474203.68940HepG2MATR3
FHL2ENSG00000115641.14419.76840693.50830-0.724302.351901.76550HepG2NCBP2
FHL2ENSG00000115641.14265.25350443.65510-0.742103.899502.20730HepG2NKRF
FHL2ENSG00000115641.14867.21010705.513300.297602.451801.73680HepG2NOL12
FHL2ENSG00000115641.1425.7863091.15780-1.821805.945904.87540HepG2NSUN2
FHL2ENSG00000115641.143211.997201436.573801.160703.112802.16860HepG2PABPC1
FHL2ENSG00000115641.14365.88400483.05010-0.400802.922302.05390HepG2PARN
FHL2ENSG00000115641.14321.50650626.60890-0.9627014.8142013.59010HepG2PCBP1
FHL2ENSG00000115641.14285.42940518.35910-0.860805.745004.29600HepG2PCBP2
FHL2ENSG00000115641.14476.26480297.141600.680503.323101.42920HepG2PES1
FHL2ENSG00000115641.14316.18810435.25730-0.461102.715701.98470HepG2PPIL4
FHL2ENSG00000115641.1487.38650208.24130-1.252809.251707.95690HepG2PRPF4
FHL2ENSG00000115641.14165.74520544.91490-1.7171017.9080015.29220HepG2PRPF6
FHL2ENSG00000115641.14122.68260253.10240-1.044806.614405.42660HepG2PRPF8
FHL2ENSG00000115641.14239.13310673.50030-1.4939024.2745022.74620HepG2PUF60
FHL2ENSG00000115641.14445.15130714.98100-0.683609.917108.94090HepG2PUM1
FHL2ENSG00000115641.14496.34940714.43970-0.525504.613503.75810HepG2PUM2
FHL2ENSG00000115641.14203.83260318.24950-0.642804.820704.04970HepG2PUS1
FHL2ENSG00000115641.14537.21480690.50960-0.362202.558801.95410HepG2QKI
FHL2ENSG00000115641.14972.17710500.199600.958606.580905.51820HepG2RAVER1
FHL2ENSG00000115641.14846.23290307.406001.4608030.7319028.43480HepG2RBM15
FHL2ENSG00000115641.14323.41450555.66630-0.780806.559805.02750HepG2RBM27
FHL2ENSG00000115641.14251.23820451.22600-0.844806.318104.71420HepG2RCC2
FHL2ENSG00000115641.14304.42610709.59200-1.2209020.4566019.24840HepG2NELFE
FHL2ENSG00000115641.14340.33880660.92400-0.9575014.3904013.15410HepG2RECQL
FHL2ENSG00000115641.14389.31890286.965200.440002.117501.51020HepG2RPLP0
FHL2ENSG00000115641.14285.07710491.40140-0.785504.668003.45280HepG2RPS10
FHL2ENSG00000115641.14169.92110325.10440-0.936007.410306.46320HepG2RPS19
FHL2ENSG00000115641.14196.81420512.46460-1.3806016.6088014.77030HepG2RPS2
FHL2ENSG00000115641.14252.978001579.34960-2.6422010.204108.70680HepG2RPS3A
FHL2ENSG00000115641.14696.832601499.35690-1.105503.287601.59290HepG2SBDS
FHL2ENSG00000115641.14229.41010326.22720-0.507902.490701.59660HepG2SERBP1
FHL2ENSG00000115641.1439.48680136.94860-1.794208.509707.27490HepG2SF3A3
FHL2ENSG00000115641.14431.43400663.80400-0.621606.935406.06630HepG2SF3B4
FHL2ENSG00000115641.14346.26520506.81920-0.549605.508604.65240HepG2SMN1
FHL2ENSG00000115641.14167.8781070.976601.241903.130901.71670HepG2SNRNP200
FHL2ENSG00000115641.141917.88640488.534001.9729091.3039089.46720HepG2SRFBP1
FHL2ENSG00000115641.14227.41400692.88500-1.6073034.6976033.43610HepG2SRSF1
FHL2ENSG00000115641.141647.93420563.713701.5475070.0789068.08020HepG2SRSF9
FHL2ENSG00000115641.1451.36760424.19480-3.0458036.8673035.49250HepG2SSB
FHL2ENSG00000115641.14707.01540467.456400.596803.169501.87610HepG2SUB1
FHL2ENSG00000115641.1458.26870100.20240-0.782102.085801.44360HepG2TARDBP
FHL2ENSG00000115641.1449.16580458.12500-3.2200031.3057028.37450HepG2TBRG4
FHL2ENSG00000115641.14376.08770218.984800.780104.686603.43750HepG2TFIP11
FHL2ENSG00000115641.14779.50040572.254200.445803.130902.24590HepG2TIA1
FHL2ENSG00000115641.14145.45360474.22850-1.7050027.1127025.84350HepG2TIAL1
FHL2ENSG00000115641.14714.44670478.416900.578507.008806.18240HepG2TRIM56
FHL2ENSG00000115641.14128.04150235.33550-0.878101.961501.42270HepG2U2AF1
FHL2ENSG00000115641.14143.68030299.10190-1.057806.040204.51450HepG2UPF2
FHL2ENSG00000115641.14260.98410550.11550-1.075808.805207.02310HepG2XRCC6
FHL2ENSG00000115641.14121.10010321.64870-1.4093012.4243010.91210HepG2XRN2
FHL2ENSG00000115641.14416.89310133.574501.6419027.9853026.70890HepG2ZNF622
FHL2ENSG00000115641.14338.75770499.79370-0.561103.034801.67240HepG2ZRANB2
FHL2ENSG00000115641.141137.35740713.714900.6722011.8147010.73440K562AGGF1
FHL2ENSG00000115641.14940.93520742.651100.341302.416401.80550K562AKAP8L
FHL2ENSG00000115641.14131.26430285.47790-1.120904.528703.11220K562CCAR1
FHL2ENSG00000115641.14741.03230562.283000.398102.757501.47760K562CIRBP
FHL2ENSG00000115641.14165.87260263.88400-0.669803.698402.79350K562CPSF6
FHL2ENSG00000115641.14591.66130409.063300.532304.127102.80050K562CSTF2
FHL2ENSG00000115641.141706.530101190.810600.519006.798405.28970K562CELF1
FHL2ENSG00000115641.14981.86360799.155600.296902.635701.78470K562DKC1
FHL2ENSG00000115641.14307.01830469.08610-0.611503.763102.53980K562EIF3D
FHL2ENSG00000115641.14421.17870304.628400.467303.177202.32670K562EIF3G
FHL2ENSG00000115641.14348.15240548.59610-0.656005.609604.44530K562EIF4A3
FHL2ENSG00000115641.14460.58630348.496900.402202.105501.36190K562FIP1L1
FHL2ENSG00000115641.14456.28270570.51630-0.322302.145401.60020K562FXR1
FHL2ENSG00000115641.14355.34030623.63370-0.811509.365207.52080K562HNRNPA1
FHL2ENSG00000115641.14657.50080347.675100.919203.668402.19680K562HNRNPA2B1
FHL2ENSG00000115641.14722.35260509.207800.504304.424703.05360K562HNRNPL
FHL2ENSG00000115641.14689.34380472.432500.545004.310303.32330K562HSPD1
FHL2ENSG00000115641.14845.09950524.681800.687605.272603.67140K562IGF2BP2
FHL2ENSG00000115641.14956.81580754.443300.342702.262301.32190K562MAK16
FHL2ENSG00000115641.141130.50760882.919500.356502.823001.90260K562MBNL1
FHL2ENSG00000115641.14622.125101032.19950-0.730408.421606.49930K562MSI2
FHL2ENSG00000115641.14820.57400618.862200.406902.066001.32710K562NAA15
FHL2ENSG00000115641.14639.06040303.932801.072105.292803.80040K562PABPN1
FHL2ENSG00000115641.14433.67050631.31700-0.541803.651402.69360K562PCBP3
FHL2ENSG00000115641.14345.83960484.23760-0.485603.308502.42790K562POLR2G
FHL2ENSG00000115641.14620.18170395.669700.648305.741104.48600K562PPIG
FHL2ENSG00000115641.14686.63240361.160900.926803.394401.71780K562PPP1R8
FHL2ENSG00000115641.14287.04360426.43020-0.571003.423602.58730K562PRPF8
FHL2ENSG00000115641.14840.990601056.58180-0.329202.450001.68400K562PUF60
FHL2ENSG00000115641.14908.52880736.517400.302701.889601.42450K562PUS1
FHL2ENSG00000115641.14674.31120513.640800.392602.659001.83630K562RBM22
FHL2ENSG00000115641.14828.32580416.363300.992303.995401.39810K562DROSHA
FHL2ENSG00000115641.14585.41980277.848001.075103.801802.32570K562SF1
FHL2ENSG00000115641.14588.16490450.097600.385902.809801.94780K562SF3B4
FHL2ENSG00000115641.14644.16980338.572500.927902.603001.35580K562SFPQ
FHL2ENSG00000115641.14610.11990478.071200.351802.562801.43950K562SRSF7
FHL2ENSG00000115641.14316.42450485.70860-0.618205.133304.00660K562SYNCRIP
FHL2ENSG00000115641.14665.93910503.124400.404402.596901.54290K562TRA2A
FHL2ENSG00000115641.14833.80200639.589100.382503.660802.18870K562TROVE2
FHL2ENSG00000115641.14337.97650516.28420-0.611206.548405.29770K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FHL2 is not available on ENCORE database.





11 RBPs can affect the splicing of FHL2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFHL2ENSG00000115641.14chr2-1060131031060131541060028171060029971060152981060156810.377000.000930.03531includedK562PRPF8
SEFHL2ENSG00000115641.14chr2-106013103106013154106002817106002997106015426106015518-0.136000.002740.06722excludedK562AKAP8L
SEFHL2ENSG00000115641.14chr2-1060131031060131541060028171060029971060152981060156810.503000.000000.00000includedK562FXR1
SEFHL2ENSG00000115641.14chr2-1060131031060131541060028171060029971060152981060156810.291000.000030.01079includedK562DROSHA
SEFHL2ENSG00000115641.14chr2-106013103106013154106002817106002997106015298106015681-0.212000.000070.01029excludedHepG2DDX6
SEFHL2ENSG00000115641.14chr2-1060131031060131541060028171060029971060152981060156810.383000.002240.04791includedHepG2SRSF1
SEFHL2ENSG00000115641.14chr2-1060131031060131541060028171060029971060152981060156810.390000.000110.01637includedHepG2SUPV3L1
SEFHL2ENSG00000115641.14chr2-106013103106013154106002817106002997106015426106015518-0.170000.000830.02390excludedK562AGGF1
SEFHL2ENSG00000115641.14chr2-1060131031060131541060028171060029971060152981060156810.400000.000000.00087includedHepG2DDX55
SEFHL2ENSG00000115641.14chr2-1060131031060131541060028171060029971060152981060156810.449000.000240.09992includedK562AARS
SEFHL2ENSG00000115641.14chr2-1060131031060131541060028171060029971060152981060156810.398000.000560.09757includedHepG2FUS
MXEFHL2ENSG00000115641.14chr2-105984026105984196105990015105990190105979741105979928106002817106002997-0.153000.003290.062962includedHepG2DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FHL2 is not avaliable on ENCORE database.