ESPN

General Information

Gene Name       : ESPN
Gene ID             : ENSG00000187017.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ESPN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ESPNENSG00000187017.160.000.000.00ENCSR000AEF
HepG2ESPNENSG00000187017.1656.277.6331.95ENCSR985KAT
K562ESPNENSG00000187017.160.080.050.07ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ESPN is not avaliable on ENCORE database.



Proteins bound to RNA
  • ESPN RNA is bound by 30 proteins.  







eCLIP assay for ESPN is not avaliable on ENCORE database.





30 proteins are bound to ESPN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr165205106520652+3'-UTR,intron-Distal3.7455611.04347HepG2UPF1
chr165207166520848+3'-UTR,intron-Distal4.3671815.18786HepG2UPF1
chr165208786520977+3'-UTR,intron-Distal4.0075613.13293HepG2PCBP2
chr165202836520424+3'-UTR,intron-Distal3.3831618.12205HepG2LARP4
chr165207556520864+3'-UTR,intron-Distal3.291423.84083HepG2IGF2BP3
chr165203266520377+3'-UTR,intron-Distal4.458734.33022HepG2HNRNPK
chr165203176520401+3'-UTR,intron-Distal3.120175.11134HepG2PCBP2
chr165206526520714+3'-UTR,intron-Distal3.398495.45714HepG2UPF1
chr165202056520283+3'-UTR,intron-Distal,intron-Proximal3.260788.24214HepG2LARP4
chr165212296521302+3'-UTR,CDS,intron-Proximal3.721826.16549HepG2U2AF2
chr165202036520274+3'-UTR,intron-Distal,intron-Proximal3.236835.75977HepG2UPF1
chr165086326508708+5'-UTR,CDS,intron-Proximal5.232096.15027K562EFTUD2
chr165086936508752+5'-UTR,CDS,intron-Proximal3.106215.78238HepG2PPIG
chr165086356508759+5'-UTR,CDS,intron-Proximal4.6044312.26180HepG2AQR
chr165086936508761+5'-UTR,CDS,intron-Proximal3.8422319.00134HepG2DDX3X
chr164849876485132+5'-UTR,CDS4.041525.66107K562FXR2
chr165085766508627+5'-UTR,intron-Distal,intron-Proximal5.0780414.03816HepG2DDX3X
chr165172436517308+CDS,intron-Proximal3.1504712.34748HepG2G3BP1
chr165006276500747+CDS,intron-Proximal3.160375.61109K562RBFOX2
chr165172386517324+CDS,intron-Proximal3.8590315.66093HepG2PPIG
chr165120636512154+CDS3.907777.91657HepG2PPIG
chr165089366508998+CDS,intron-Distal,intron-Proximal5.148895.16101HepG2PCBP1
chr165201076520196+CDS,intron-Proximal3.030504.04186HepG2PPIG
chr165006586500749+CDS,intron-Proximal3.5486213.75318K562AQR
chr165172306517302+CDS,intron-Proximal4.031906.61645HepG2BUD13
chr165116046511717+CDS,intron-Proximal3.3738014.57854HepG2AQR
chr165006426500721+CDS,intron-Proximal5.012435.02679K562BUD13
chr165119666512057+CDS3.058167.30608HepG2RPS3
chr165174186517454+CDS,intron-Proximal3.328854.40420HepG2PPIG
chr164851326485201+CDS4.288153.42335K562FXR2
chr165200676520138+CDS3.509109.11529HepG2LARP4
chr165090186509144+CDS,intron-Distal3.297447.51354HepG2UPF1
chr165174196517472+CDS,intron-Proximal3.9118712.12948HepG2AQR
chr165173086517326+CDS,intron-Proximal3.702908.03852HepG2G3BP1
chr165117836511808+CDS4.347413.79199HepG2PPIG
chr165148216514887+intron-Distal3.060745.00212HepG2RBM15
chr165080176508078+intron-Distal4.446394.23351K562BUD13
chr165139446513997+intron-Distal5.552727.55877HepG2SLTM
chr165051166505272+intron-Distal4.619698.86029K562AGGF1
chr165179716518068+intron-Distal4.271793.77753HepG2ILF3
chr165194926519545+intron-Distal3.439469.60323HepG2HNRNPL
chr165066876506744+intron-Distal3.699873.99908K562BUD13
chr165064536506511+intron-Distal4.186414.13881HepG2PRPF4
chr165049466505047+intron-Distal4.595843.80299K562HNRNPL
chr165055256505569+intron-Distal4.425213.93614HepG2AQR
chr165061976506259+intron-Distal3.867883.53160K562RBFOX2
chr165140356514095+intron-Distal4.595596.20747HepG2SLTM
chr165091946509248+intron-Distal,intron-Proximal3.8037310.10000HepG2EFTUD2
chr165198446519954+intron-Distal4.227038.87704HepG2HNRNPK
chr165167296516811+intron-Distal5.7051110.79848HepG2CSTF2
chr165142206514274+intron-Distal4.516246.20747HepG2SLTM
chr165111506511216+intron-Distal4.575414.13073HepG2GTF2F1
chr165078566507981+intron-Distal4.199838.55060HepG2UPF1
chr165176296517710+intron-Distal7.3071030.05789HepG2QKI
chr165168906516930+intron-Distal5.095596.38758HepG2SLTM
chr165060576506135+intron-Distal,intron-Proximal4.151404.59504K562RBFOX2
chr165137996513840+intron-Distal4.287335.10133HepG2SLTM
chr165111496511210+intron-Distal4.3210910.30373HepG2EFTUD2
chr165140956514160+intron-Distal4.171596.66289HepG2SLTM
chr165195456519606+intron-Distal3.8194311.65948HepG2HNRNPL
chr165074286507470+intron-Distal3.049023.65461K562BUD13
chr165146776514743+intron-Distal3.998613.07274HepG2SRSF9
chr165168116516884+intron-Distal4.703075.61812HepG2CSTF2
chr165051306505238+intron-Distal4.885674.94713K562HNRNPL
chr165093886509460+intron-Distal3.881653.06084HepG2HNRNPK
chr165168306516890+intron-Distal3.758604.54081HepG2SLTM
chr165080096508069+intron-Distal3.470935.39783HepG2NKRF
chr165072166507291+intron-Distal3.002463.60519K562BUD13
chr165094066509443+intron-Distal5.033186.65725HepG2DDX59
chr165198526519930+intron-Distal4.071247.66599HepG2DDX59
chr165168846516973+intron-Distal3.769815.37079HepG2CSTF2
chr165164256516509+intron-Distal4.234439.38497HepG2SLTM
chr165111446511207+intron-Distal3.625107.70534HepG2PRPF4
chr165155126515558+intron-Distal5.125046.97212HepG2SLTM
chr165079886508078+intron-Distal3.027573.80948HepG2GRSF1
chr165060406506105+intron-Distal,intron-Proximal3.876693.99908K562BUD13
chr165116076511658+intron-Proximal3.149026.28639HepG2EFTUD2
chr165199976520025+intron-Proximal4.338263.25089HepG2AQR
chr165086446508687+intron-Proximal3.329963.57490HepG2NKRF
chr165115876511662+intron-Proximal3.6199610.85577HepG2PRPF4
chr165086426508693+intron-Proximal3.797738.46496HepG2BUD13
chr165200256520048+intron-Proximal5.285728.16909HepG2AQR
chr165086506508701+intron-Proximal4.861687.56947K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ESPN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ESPN is not available on ENCORE database.

  • 121 RBPs can affect the levels of ESPN.  








The Knockdown/knockout RNA-Seq assay for ESPN is not available on ENCORE database.





121 RBPs can affect the gene expression of ESPN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ESPNENSG00000187017.101119.519601911.06170-0.771506.383605.53830HepG2ACO1
ESPNENSG00000187017.10687.54300357.429100.943702.888301.87090HepG2ADAR
ESPNENSG00000187017.10605.665902526.87610-2.060804.010103.38680HepG2AKAP1
ESPNENSG00000187017.10938.91070467.864501.004803.207402.23830HepG2BCLAF1
ESPNENSG00000187017.10248.90120707.07380-1.506303.700403.01980HepG2BOP1
ESPNENSG00000187017.101293.046601910.23980-0.563005.235804.37320HepG2CKAP4
ESPNENSG00000187017.10998.38410649.075800.621102.375301.73150HepG2CPSF6
ESPNENSG00000187017.10690.99330366.550100.914604.172102.91840HepG2YBX3
ESPNENSG00000187017.101186.88980767.139900.6295012.9753011.56980HepG2DAZAP1
ESPNENSG00000187017.103797.000202080.429200.867903.394402.71810HepG2DDX6
ESPNENSG00000187017.10804.78710359.894701.160908.343707.17570HepG2DNAJC21
ESPNENSG00000187017.10961.10710356.760401.4296046.8286044.41560HepG2DNAJC2
ESPNENSG00000187017.101387.03730724.992300.9359014.4064012.65670HepG2EIF4G2
ESPNENSG00000187017.101118.160201867.08780-0.739702.606301.79570HepG2EWSR1
ESPNENSG00000187017.10883.567302188.16420-1.308304.874103.87700HepG2FIP1L1
ESPNENSG00000187017.101307.882602096.85560-0.6810011.155709.62210HepG2FUBP3
ESPNENSG00000187017.101820.20020735.623001.3070016.2229014.79680HepG2GPKOW
ESPNENSG00000187017.10940.04720398.964301.2364015.0310013.53310HepG2HNRNPF
ESPNENSG00000187017.101178.75760698.807100.7542017.6596016.09270HepG2HNRNPL
ESPNENSG00000187017.101654.06830702.032601.2363012.4940011.28190HepG2HNRNPLL
ESPNENSG00000187017.10907.509201508.95510-0.733603.119602.11290HepG2HNRNPM
ESPNENSG00000187017.10931.87730401.493301.2147020.7389019.19040HepG2HNRNPU
ESPNENSG00000187017.10967.24810392.860101.2998026.6122024.65480HepG2IGF2BP1
ESPNENSG00000187017.10708.704201973.30810-1.477402.575301.62840HepG2IGF2BP3
ESPNENSG00000187017.10614.68570410.109600.583707.371306.23590HepG2ILF2
ESPNENSG00000187017.101174.37640595.576500.979402.906601.67950HepG2KHDRBS1
ESPNENSG00000187017.102267.076101746.697100.376104.745903.41790HepG2KIF1C
ESPNENSG00000187017.101042.214002242.61060-1.105501.964801.42880HepG2MATR3
ESPNENSG00000187017.101041.615301769.71140-0.764703.302602.42250HepG2MSI2
ESPNENSG00000187017.101436.79640716.320701.004103.386002.30630HepG2MTPAP
ESPNENSG00000187017.101035.45190460.086801.1702013.9748011.10620HepG2NIP7
ESPNENSG00000187017.101122.13310760.694100.560807.388706.15820HepG2NOL12
ESPNENSG00000187017.101942.52790622.598701.6415019.7431017.97870HepG2NSUN2
ESPNENSG00000187017.101281.833702148.39610-0.745106.838005.95170HepG2PCBP1
ESPNENSG00000187017.102445.247901817.179800.428203.946301.88710HepG2PES1
ESPNENSG00000187017.101398.05080358.097401.9649013.2338011.69260HepG2PPIL4
ESPNENSG00000187017.101123.523902186.27910-0.960407.923407.09480HepG2PTBP1
ESPNENSG00000187017.102321.87460726.147801.6769055.3217053.07000HepG2PUF60
ESPNENSG00000187017.10528.36520770.83650-0.544907.661306.77690HepG2PUM1
ESPNENSG00000187017.10568.38490770.27440-0.438503.772702.99450HepG2PUM2
ESPNENSG00000187017.101494.250201946.48080-0.381402.961102.32950HepG2PUS1
ESPNENSG00000187017.10252.472801528.48580-2.5979062.4821060.66300HepG2RBM22
ESPNENSG00000187017.101320.07260498.344201.405308.750606.87250HepG2RCC2
ESPNENSG00000187017.101417.160702432.94780-0.779707.013106.22050HepG2NELFE
ESPNENSG00000187017.101456.290602266.27030-0.638004.627303.85880HepG2RECQL
ESPNENSG00000187017.10390.43680800.26760-1.035401.972701.44600HepG2RPS19
ESPNENSG00000187017.10156.70200403.61160-1.364902.350201.61960HepG2RRP9
ESPNENSG00000187017.101133.43760357.539001.6644014.1616012.87280HepG2SAFB2
ESPNENSG00000187017.101309.85270590.864701.148403.289601.86670HepG2SART3
ESPNENSG00000187017.101556.575702292.82640-0.558803.824403.02640HepG2SF3A3
ESPNENSG00000187017.101065.945002275.82980-1.0943010.852709.79970HepG2SF3B4
ESPNENSG00000187017.102247.92640696.259501.6908022.6008020.98140HepG2SLBP
ESPNENSG00000187017.10803.830601726.31600-1.1027022.6266021.55320HepG2SRFBP1
ESPNENSG00000187017.10343.917902375.62420-2.7882038.8645037.54240HepG2SRSF1
ESPNENSG00000187017.101098.20380716.963400.6151010.332009.22480HepG2SRSF5
ESPNENSG00000187017.10637.13020391.989500.700702.360301.71390HepG2SRSF7
ESPNENSG00000187017.101251.939001932.82650-0.626504.890704.19530HepG2SRSF9
ESPNENSG00000187017.101765.365401498.759300.236102.061101.60220HepG2SSB
ESPNENSG00000187017.10473.669002135.72150-2.1728024.2218022.78990HepG2TAF15
ESPNENSG00000187017.10549.64350390.071300.494701.739201.32310HepG2TIAL1
ESPNENSG00000187017.101325.86230393.616701.7520071.8520069.55130HepG2TRIM56
ESPNENSG00000187017.101370.40340709.413200.949802.666601.81060HepG2TUFM
ESPNENSG00000187017.10762.478301871.12280-1.295104.888904.06700HepG2U2AF1
ESPNENSG00000187017.101460.09930750.901100.959304.624203.52240HepG2UBE2L3
ESPNENSG00000187017.10782.220101963.15090-1.3275034.9801033.21010HepG2UTP3
ESPNENSG00000187017.101560.68590562.131901.473108.679706.75700HepG2XPO5
ESPNENSG00000187017.101456.70130518.958801.488909.179807.88050HepG2XRN2
ESPNENSG00000187017.10610.38800869.97930-0.511302.219301.60820HepG2ZC3H8
ESPNENSG00000187017.101722.909502236.33370-0.376305.285404.59140HepG2ZNF622
ESPNENSG00000187017.1017.2691066.22160-1.939103.575402.21530K562AARS
ESPNENSG00000187017.10134.2202043.041401.640704.133302.01800K562ADAR
ESPNENSG00000187017.1079.0250043.573100.858802.162601.65000K562AGGF1
ESPNENSG00000187017.10171.5415045.339401.9196013.5675011.95470K562AKAP8L
ESPNENSG00000187017.10634.6030069.460203.191509.429708.45040K562AQR
ESPNENSG00000187017.1099.2033047.571201.060203.871302.77470K562ATP5C1
ESPNENSG00000187017.1094.6279039.116001.274402.798601.83300K562BCLAF1
ESPNENSG00000187017.10160.4792042.160201.9283010.261207.85130K562CCAR1
ESPNENSG00000187017.1031.144908.956001.798002.812701.52110K562CIRBP
ESPNENSG00000187017.10343.8308093.859701.8730014.0610010.88240K562CKAP4
ESPNENSG00000187017.10169.3059058.966601.521602.900401.80630K562CNOT7
ESPNENSG00000187017.10102.1641029.675301.783507.010105.21230K562CSTF2
ESPNENSG00000187017.10274.90170129.339301.087706.364404.89700K562CELF1
ESPNENSG00000187017.10108.0836051.123101.080004.061502.27010K562DDX19B
ESPNENSG00000187017.10260.93170121.106701.107307.089205.12030K562DDX21
ESPNENSG00000187017.10244.98040102.600301.2555010.776909.58650K562DDX47
ESPNENSG00000187017.10150.5418047.215201.672707.588405.23560K562DHX30
ESPNENSG00000187017.10190.9808049.761101.940203.059701.70810K562EEF2
ESPNENSG00000187017.10176.8184042.877402.043904.726603.37340K562EIF3A
ESPNENSG00000187017.10549.98440105.115202.3873046.9244043.71300K562EIF4G2
ESPNENSG00000187017.1099.00750253.50070-1.356407.868005.69770K562EXOSC5
ESPNENSG00000187017.10162.0552068.303001.246406.824605.44450K562FIP1L1
ESPNENSG00000187017.1037.2407094.51030-1.343602.393101.59600K562FMR1
ESPNENSG00000187017.1024.5470049.56410-1.013701.874301.35720K562FXR1
ESPNENSG00000187017.10340.5792085.168701.9995027.8915024.97610K562GLRX3
ESPNENSG00000187017.10223.5402088.634201.334508.928807.49390K562GPKOW
ESPNENSG00000187017.10243.0512052.976702.197709.692606.47160K562HNRNPA0
ESPNENSG00000187017.10370.79990106.587501.7985010.948809.01070K562HNRNPA1
ESPNENSG00000187017.10224.0555072.343201.6308011.1416010.01170K562HNRNPC
ESPNENSG00000187017.108.8423056.18960-2.667806.613505.07930K562HNRNPM
ESPNENSG00000187017.1054.1486092.59110-0.773902.033301.34680K562HSPD1
ESPNENSG00000187017.1026.480908.515301.636702.471701.36230K562IGF2BP3
ESPNENSG00000187017.10102.4347048.117701.090002.148201.43160K562KIF1C
ESPNENSG00000187017.10166.7419075.722601.138703.258602.23670K562KRR1
ESPNENSG00000187017.1024.2174070.20800-1.535602.751401.36800K562LARP7
ESPNENSG00000187017.1026.543508.783001.595502.274601.50830K562MAGOH
ESPNENSG00000187017.1046.176708.761102.397903.214002.21420K562MATR3
ESPNENSG00000187017.1015.1677047.58310-1.649403.273701.92650K562NCBP2
ESPNENSG00000187017.10204.6116099.502501.040006.667005.57670K562NSUN2
ESPNENSG00000187017.1065.4648027.769101.237102.273901.39390K562PABPN1
ESPNENSG00000187017.101081.72310322.449701.746103.862902.88100K562PCBP3
ESPNENSG00000187017.10666.61660247.308801.430402.553101.78640K562POLR2G
ESPNENSG00000187017.10137.2455045.008201.608407.061103.88840K562RBFOX2
ESPNENSG00000187017.10125.3151043.811301.516107.480506.53590K562RBM15
ESPNENSG00000187017.10187.86650106.244100.822203.628001.77830K562RBM17
ESPNENSG00000187017.1039.052708.169702.257004.917503.75700K562RBM22
ESPNENSG00000187017.10160.1382052.684801.603805.056302.84150K562RPS3A
ESPNENSG00000187017.10104.5358040.305001.374904.096702.85000K562RPS3
ESPNENSG00000187017.10200.6232079.909301.328005.783603.20320K562SAFB2
ESPNENSG00000187017.10435.28930220.424400.981605.908704.32770K562SAFB
ESPNENSG00000187017.10245.8364053.737502.193604.916702.77400K562SBDS
ESPNENSG00000187017.10412.22410227.863800.855203.362101.74640K562SDAD1
ESPNENSG00000187017.1044.7204098.16260-1.134204.166203.17880K562SF3A3
ESPNENSG00000187017.10123.7366046.404801.414803.032701.70470K562SLBP
ESPNENSG00000187017.10178.87060100.567800.830604.125103.00550K562SRPK2
ESPNENSG00000187017.1081.4931038.900401.066802.613201.59630K562SRSF4
ESPNENSG00000187017.1027.227307.912501.782702.591801.58170K562SRSF5
ESPNENSG00000187017.10161.8523081.945500.981804.311902.68460K562STAU1
ESPNENSG00000187017.10242.19700100.050201.275403.463401.77800K562SUCLG1
ESPNENSG00000187017.1061.73070248.08640-2.0068011.8014010.10960K562SYNCRIP
ESPNENSG00000187017.10102.924808.464903.603906.951805.78030K562TARDBP
ESPNENSG00000187017.1028.186908.167001.787002.566201.78130K562TIA1
ESPNENSG00000187017.10189.2902079.848801.245207.459505.06380K562TRIP6
ESPNENSG00000187017.10477.50560234.429001.026308.822405.78750K562TRNAU1AP
ESPNENSG00000187017.10248.79460176.030100.499002.550501.33670K562TROVE2
ESPNENSG00000187017.10123.0781054.449901.176504.939303.33480K562UTP3
ESPNENSG00000187017.10246.7051090.277901.450205.110703.90350K562WDR3
ESPNENSG00000187017.10321.6098093.866001.7765024.2325022.11420K562WDR43
ESPNENSG00000187017.10214.4350082.372401.380205.313603.52370K562WRN
ESPNENSG00000187017.10280.4801078.212301.8423020.0973017.65200K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ESPN is not available on ENCORE database.





7 RBPs can affect the splicing of ESPN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEESPNENSG00000187017.10chr1+650895265091516508844650886265116626511808-0.178000.001220.06520excludedHepG2NCBP2
SEESPNENSG00000187017.10chr1+6510503651053065089526509151651166265118080.281000.000040.00401includedHepG2PTBP1
SEESPNENSG00000187017.10chr1+6510503651053065089526509151651166265118080.469000.000000.00003includedHepG2SRSF1
SEESPNENSG00000187017.10chr1+650895265091516508844650886265116626511808-0.337000.001340.03236excludedHepG2SRSF1
SEESPNENSG00000187017.10chr1+651189265120996511717651180865172436517323-0.054000.000130.00609excludedHepG2SF3A3
SEESPNENSG00000187017.10chr1+650895265091516508844650886265116626511808-0.202000.001380.06182excludedHepG2PCBP1
SEESPNENSG00000187017.10chr1+651050365105306508952650915165116626511808-0.216000.000230.06034excludedHepG2NOL12
SEESPNENSG00000187017.10chr1+650895265091516508844650886265116626511808-0.224000.000480.02576excludedHepG2SF3B4
A5SSESPNENSG00000187017.10chr1+650870065091516508700650886265116626511808-0.188000.000920.09276shorterHepG2NCBP2
A5SSESPNENSG00000187017.10chr1+650870065091516508700650886265116626511808-0.226000.000510.04263shorterHepG2SF3B4
A5SSESPNENSG00000187017.10chr1+650870065091516508700650886265116626511808-0.337000.001470.07937shorterHepG2SRSF1
MXEESPNENSG00000187017.10chr1+651166265118086511892651215665087006508862651724365173230.054000.000000.000461includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ESPN is not avaliable on ENCORE database.