ERAP1

General Information

Gene Name       : ERAP1
Gene ID             : ENSG00000164307.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ERAP1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ERAP1ENSG00000164307.1248.3666.7657.56ENCSR000AEF
HepG2ERAP1ENSG00000164307.1240.0327.8633.95ENCSR985KAT
K562ERAP1ENSG00000164307.1216.8721.2119.04ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ERAP1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ERAP1 RNA is bound by 8 proteins.  







eCLIP assay for ERAP1 is not avaliable on ENCORE database.





8 proteins are bound to ERAP1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr59611160296111707-3'-UTR,intron-Distal,intron-Proximal3.315494.00430HepG2UPF1
chr59611026696110335-3'-UTR,intron-Distal3.518746.04577K562FAM120A
chr59613656496136684-3'-UTR,CDS,intron-Distal,intron-Proximal3.729766.81385HepG2BCLAF1
chr59613658896136704-3'-UTR,CDS,intron-Distal,intron-Proximal3.563958.65614K562SND1
chr59611052896110567-3'-UTR,intron-Distal4.078933.54010K562UPF1
chr59611151096111578-3'-UTR,intron-Distal,intron-Proximal3.249263.73678HepG2UPF1
chr59613929096139363-3'-UTR,5'-UTR,CDS,intron-Distal3.897234.98210K562SND1
chr59611039196110460-3'-UTR,intron-Distal4.247506.48274K562UPF1
chr59611144496111503-3'-UTR,intron-Distal4.199833.45012HepG2UPF1
chr59613289696133007-3'-UTR,CDS,intron-Distal,intron-Proximal3.8314910.07444K562SND1
chr59611022696110291-3'-UTR,intron-Distal4.591005.51435HepG2ZC3H11A
chr59611026896110358-3'-UTR,intron-Distal3.699095.44797K562ZC3H11A
chr59613294096133013-3'-UTR,CDS,intron-Distal,intron-Proximal3.698863.68471HepG2BCLAF1
chr59613078896130867-CDS,intron-Distal,intron-Proximal4.669886.27746HepG2LIN28B
chr59611616296116202-CDS,intron-Distal4.130223.60906K562SND1
chr59611749296117560-CDS,intron-Distal,intron-Proximal4.009926.07295HepG2SND1
chr59611751396117559-CDS,intron-Distal,intron-Proximal3.028753.14823K562SND1
chr59613074496130798-CDS,intron-Distal,intron-Proximal4.307967.35426K562SND1
chr59611218196112225-CDS,intron-Distal4.558205.31986K562SND1
chr59612910396129150-CDS,intron-Distal4.727776.21049K562SND1
chr59613079196130823-CDS,intron-Distal3.291223.30795HepG2SND1
chr59612919696129216-CDS,intron-Distal3.476164.08796K562SND1
chr59611678196116842-CDS,intron-Distal3.468043.30795HepG2SND1
chr59612427896124345-CDS,intron-Distal3.850685.86901K562SND1
chr59611678896116847-CDS,intron-Distal3.237685.80107K562SND1
chr59611741796117458-CDS,intron-Distal4.321234.57227K562SND1
chr59612954496129601-CDS,intron-Distal4.5760110.97979K562SND1
chr59611876196118840-CDS,intron-Distal4.707664.94988HepG2SND1
chr59612950496129543-CDS,intron-Distal,intron-Proximal4.257108.55362K562SND1
chr59613656896136619-CDS,intron-Distal,intron-Proximal3.203433.03966HepG2SND1
chr59612423396124289-CDS,intron-Distal,intron-Proximal3.452183.85049HepG2SND1
chr59613080896130868-CDS,intron-Distal,intron-Proximal4.370914.23668K562LIN28B
chr59612960196129660-CDS,intron-Distal5.6745312.54806K562SND1
chr59612429696124391-CDS,intron-Distal,intron-Proximal4.813425.84094HepG2SND1
chr59612950596129554-CDS,intron-Distal,intron-Proximal3.421483.03966HepG2SND1
chr59614326796143442-intron-Distal4.167405.72412HepG2FAM120A
chr59614338396143480-intron-Distal3.134063.51554HepG2PRPF4
chr59614331596143454-intron-Distal3.937413.44758HepG2CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ERAP1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ERAP1 is not available on ENCORE database.

  • 125 RBPs can affect the levels of ERAP1.  








The Knockdown/knockout RNA-Seq assay for ERAP1 is not available on ENCORE database.





125 RBPs can affect the gene expression of ERAP1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ERAP1ENSG00000164307.81008.268001292.72210-0.358502.921401.82510HepG2AATF
ERAP1ENSG00000164307.81107.219301624.36630-0.5529011.8209010.75160HepG2ACO1
ERAP1ENSG00000164307.81263.430302467.61910-0.9658012.9561011.89230HepG2AKAP1
ERAP1ENSG00000164307.82040.086201560.766700.386303.443801.89020HepG2ATP5C1
ERAP1ENSG00000164307.8643.110301012.86310-0.655304.995303.73300HepG2BCCIP
ERAP1ENSG00000164307.81208.15400903.819000.418603.531902.86450HepG2BOP1
ERAP1ENSG00000164307.81940.848501296.003300.582507.612705.67160HepG2BUD13
ERAP1ENSG00000164307.81006.947101624.01420-0.6896018.7634017.36950HepG2CKAP4
ERAP1ENSG00000164307.82277.80810829.744301.4568036.5590034.46150HepG2CPSF6
ERAP1ENSG00000164307.81961.104501424.469900.461104.931303.48140HepG2CPSF7
ERAP1ENSG00000164307.81038.089201502.30660-0.5332011.270909.81620HepG2DDX19B
ERAP1ENSG00000164307.81465.809001210.486700.276002.678201.53860HepG2DDX1
ERAP1ENSG00000164307.81798.391501395.740900.365603.713802.64470HepG2DDX24
ERAP1ENSG00000164307.81491.772502363.89870-0.664107.607806.61750HepG2DDX3X
ERAP1ENSG00000164307.81562.19320942.239200.729304.309803.10550HepG2DDX59
ERAP1ENSG00000164307.81437.678601144.813900.328502.637501.67820HepG2DHX30
ERAP1ENSG00000164307.8823.321801176.48110-0.514909.417108.30000HepG2DNAJC2
ERAP1ENSG00000164307.81138.341001438.42670-0.337602.247401.41480HepG2EEF2
ERAP1ENSG00000164307.82984.575101952.109300.612407.060606.14510HepG2EIF2S1
ERAP1ENSG00000164307.8823.283102100.33190-1.3512018.8654017.18490HepG2EIF4B
ERAP1ENSG00000164307.82038.842301753.221200.217602.182801.42430HepG2EIF4G1
ERAP1ENSG00000164307.82357.952501679.480400.489405.262104.15750HepG2EIF4G2
ERAP1ENSG00000164307.81745.863702112.39900-0.274903.436502.77750HepG2ETF1
ERAP1ENSG00000164307.81198.176101587.29700-0.405704.165603.14040HepG2EWSR1
ERAP1ENSG00000164307.81303.22550828.906100.652706.276504.44440HepG2FKBP4
ERAP1ENSG00000164307.81444.21270831.189000.796903.452402.31400HepG2FTO
ERAP1ENSG00000164307.81608.270201288.019100.320302.824702.02960HepG2FUBP3
ERAP1ENSG00000164307.8991.010002176.39330-1.1350020.4183018.72120HepG2FXR1
ERAP1ENSG00000164307.81869.906001550.805400.269803.355202.28570HepG2HDGF
ERAP1ENSG00000164307.81596.621801198.319600.413902.777302.12960HepG2HNRNPA1
ERAP1ENSG00000164307.8851.600701332.91370-0.646307.775206.66020HepG2HNRNPC
ERAP1ENSG00000164307.81979.100301618.852400.289804.486503.64450HepG2HNRNPL
ERAP1ENSG00000164307.8843.839101205.14190-0.514206.088804.75010HepG2HNRNPM
ERAP1ENSG00000164307.81109.181801324.10090-0.255502.693702.09520HepG2HNRNPU
ERAP1ENSG00000164307.81000.476501429.21500-0.514502.856101.62380HepG2LIN28B
ERAP1ENSG00000164307.81240.248902177.15140-0.8118010.755109.48620HepG2MAGOH
ERAP1ENSG00000164307.81767.279902189.39580-0.309001.855501.33350HepG2MATR3
ERAP1ENSG00000164307.81752.78550915.486800.936908.618706.88330HepG2MTPAP
ERAP1ENSG00000164307.81850.927901187.061400.640808.660406.57410HepG2NAA15
ERAP1ENSG00000164307.81290.831002241.01640-0.7959010.088408.92270HepG2NCBP2
ERAP1ENSG00000164307.81563.64630795.904100.9741016.1584014.51980HepG2NSUN2
ERAP1ENSG00000164307.8792.528101196.97480-0.594903.132402.18480HepG2PABPC1
ERAP1ENSG00000164307.82677.420201995.992100.423603.622102.80320HepG2PABPC4
ERAP1ENSG00000164307.81550.729301964.32030-0.341104.957604.18190HepG2PCBP1
ERAP1ENSG00000164307.81464.632001180.991400.310403.304902.50560HepG2PPIL4
ERAP1ENSG00000164307.81820.182301135.080400.6812015.9405014.33280HepG2PRPF4
ERAP1ENSG00000164307.81466.066301998.80780-0.447207.847007.02080HepG2PTBP1
ERAP1ENSG00000164307.8995.914501682.16860-0.7562012.0935010.96550HepG2PUF60
ERAP1ENSG00000164307.82292.658601785.682100.360407.530006.65130HepG2PUM1
ERAP1ENSG00000164307.82196.393501784.386500.299603.046302.34180HepG2PUM2
ERAP1ENSG00000164307.81237.268201765.58610-0.513008.254807.47050HepG2RBM22
ERAP1ENSG00000164307.82968.232301964.613800.595309.844608.62980HepG2RBM25
ERAP1ENSG00000164307.81363.706502224.44920-0.7059018.1083016.95950HepG2NELFE
ERAP1ENSG00000164307.8624.235201136.21030-0.8641013.5188012.29080HepG2RPS19
ERAP1ENSG00000164307.81077.458401513.25410-0.490002.793701.98930HepG2RPS2
ERAP1ENSG00000164307.81137.267602182.61930-0.9405011.105809.69340HepG2SF3A3
ERAP1ENSG00000164307.81100.424302080.94790-0.9192028.8376027.27900HepG2SF3B4
ERAP1ENSG00000164307.82388.654801612.908400.5664016.2290014.78890HepG2SLBP
ERAP1ENSG00000164307.81041.291201375.10410-0.401206.856105.91370HepG2SMN1
ERAP1ENSG00000164307.82433.62970988.525601.2997016.1338014.27340HepG2SNRNP70
ERAP1ENSG00000164307.81205.894601994.18480-0.7257020.2876019.25730HepG2SRFBP1
ERAP1ENSG00000164307.81503.77000948.513900.664706.770004.41090HepG2SRP68
ERAP1ENSG00000164307.8853.646702172.08730-1.3474060.3877058.82530HepG2SRSF1
ERAP1ENSG00000164307.81374.398901660.87950-0.273103.213002.54660HepG2SRSF5
ERAP1ENSG00000164307.82110.277501539.746400.454602.511801.36690HepG2SUB1
ERAP1ENSG00000164307.81460.497501179.352200.308402.382201.50480HepG2SUPT6H
ERAP1ENSG00000164307.82088.64230874.947901.2552028.3340026.48210HepG2TARDBP
ERAP1ENSG00000164307.82321.137701793.938800.371604.342903.30440HepG2TIA1
ERAP1ENSG00000164307.8752.879701286.59390-0.7731013.3024012.34520HepG2TIAL1
ERAP1ENSG00000164307.8664.96990927.89090-0.480703.045601.41310HepG2TROVE2
ERAP1ENSG00000164307.82107.291801643.384300.358603.724202.69610HepG2TUFM
ERAP1ENSG00000164307.8614.456601494.26580-1.2821018.3560016.68430HepG2U2AF1
ERAP1ENSG00000164307.8804.991501691.35190-1.071103.400002.30150HepG2U2AF2
ERAP1ENSG00000164307.8425.77200585.64680-0.459902.753601.99580HepG2UCHL5
ERAP1ENSG00000164307.82237.924201935.647800.209202.463201.79790HepG2UPF1
ERAP1ENSG00000164307.81562.359001868.79460-0.258403.119002.48950HepG2UTP3
ERAP1ENSG00000164307.8738.93400975.89130-0.401302.430501.74750HepG2XRN2
ERAP1ENSG00000164307.81439.739101120.166700.362005.469604.57620HepG2ZC3H8
ERAP1ENSG00000164307.81525.090802128.84460-0.4812012.1924011.24780HepG2ZNF622
ERAP1ENSG00000164307.82426.362601391.965900.8016012.9078010.40900K562ABCF1
ERAP1ENSG00000164307.81244.789501595.93520-0.358503.373202.00000K562APOBEC3C
ERAP1ENSG00000164307.82251.190601702.781500.402705.583904.23310K562ATP5C1
ERAP1ENSG00000164307.81802.15930764.500201.2370024.0467021.54360K562BOP1
ERAP1ENSG00000164307.81513.66350969.625200.642406.584504.34360K562BUD13
ERAP1ENSG00000164307.8756.76450495.721900.610205.516803.90510K562CCAR1
ERAP1ENSG00000164307.81525.102401104.662700.465205.644103.48570K562CEBPZ
ERAP1ENSG00000164307.82250.636701346.045000.741505.090203.59560K562CNOT7
ERAP1ENSG00000164307.81857.962501389.208300.419406.721504.96120K562CPEB4
ERAP1ENSG00000164307.81494.39820812.823700.8785015.9490014.02530K562CPSF6
ERAP1ENSG00000164307.83848.168902224.037000.7909019.4022017.08160K562CELF1
ERAP1ENSG00000164307.81654.336101269.692100.381704.910903.27070K562DDX21
ERAP1ENSG00000164307.81287.369901009.451100.350803.193202.06810K562DDX3X
ERAP1ENSG00000164307.82036.741301437.400900.502709.699408.56820K562DDX47
ERAP1ENSG00000164307.8733.27940554.986400.401802.624501.33470K562DHX30
ERAP1ENSG00000164307.8660.07350868.02430-0.395102.770601.85740K562EFTUD2
ERAP1ENSG00000164307.81604.076501108.830800.532609.664107.34770K562EIF2S1
ERAP1ENSG00000164307.82687.496201005.641101.4180062.8755060.47610K562EIF2S2
ERAP1ENSG00000164307.8958.77420504.224200.927006.706205.08870K562EIF3A
ERAP1ENSG00000164307.81287.19220929.245400.470003.000201.92010K562EIF3D
ERAP1ENSG00000164307.81030.77280838.331300.298002.629301.85130K562EIF3G
ERAP1ENSG00000164307.8723.21890949.77390-0.393203.835202.44100K562EIF4B
ERAP1ENSG00000164307.82611.210201808.688300.5297010.322408.55320K562EIF4G2
ERAP1ENSG00000164307.81500.104601064.067500.495403.479901.62250K562ESF1
ERAP1ENSG00000164307.81304.08890827.143700.656707.513606.06900K562FMR1
ERAP1ENSG00000164307.81312.67610701.128800.9047011.949709.92150K562FTO
ERAP1ENSG00000164307.8613.657601096.78420-0.8378015.8366014.49940K562FXR1
ERAP1ENSG00000164307.81448.476901120.058500.370902.064401.46600K562G3BP2
ERAP1ENSG00000164307.81374.59070954.497400.526107.593105.76750K562GLRX3
ERAP1ENSG00000164307.81116.78700775.999200.525104.199703.22710K562GPKOW
ERAP1ENSG00000164307.81545.888301111.149000.476304.660403.27840K562HNRNPA1
ERAP1ENSG00000164307.81089.82650823.160600.404803.439402.15730K562HNRNPF
ERAP1ENSG00000164307.8461.19560823.11710-0.835708.047106.32480K562HNRNPM
ERAP1ENSG00000164307.82701.481101356.641100.9936019.7416017.77180K562HSPD1
ERAP1ENSG00000164307.81472.382301116.929100.398502.633101.64070K562IGF2BP2
ERAP1ENSG00000164307.81428.659101136.153700.330402.655701.49720K562IGF2BP3
ERAP1ENSG00000164307.81806.953001229.597400.555302.823101.38640K562ILF2
ERAP1ENSG00000164307.8817.25140517.939200.657906.015803.82590K562ILF3
ERAP1ENSG00000164307.8833.13420500.467000.735207.448805.05970K562KHDRBS1
ERAP1ENSG00000164307.81115.65170662.730900.751306.257004.79090K562KRR1
ERAP1ENSG00000164307.8823.466901174.06030-0.511705.710904.49020K562MAGOH
ERAP1ENSG00000164307.81320.756201929.52810-0.546907.788006.10970K562MBNL1
ERAP1ENSG00000164307.81072.81370757.481800.502004.879703.69620K562METAP2
ERAP1ENSG00000164307.82402.577601927.862400.317502.640601.53920K562MSI2
ERAP1ENSG00000164307.81515.557301003.521500.5947010.262308.80720K562MTPAP
ERAP1ENSG00000164307.81798.921401115.047700.6899021.2736019.48990K562NSUN2
ERAP1ENSG00000164307.81858.458201293.162600.523102.838001.58850K562PABPC1
ERAP1ENSG00000164307.8614.78460982.56730-0.676503.059502.00800K562PABPN1
ERAP1ENSG00000164307.8561.764901044.66160-0.8950012.7945010.59460K562PCBP2
ERAP1ENSG00000164307.81967.388901413.574900.476804.068703.05920K562PCBP3
ERAP1ENSG00000164307.81356.413101084.272200.323002.855002.04080K562POLR2G
ERAP1ENSG00000164307.81821.677201198.011400.604504.220101.96500K562PPIL4
ERAP1ENSG00000164307.8550.59860844.69130-0.617405.553504.49020K562PRPF8
ERAP1ENSG00000164307.8638.15090826.35870-0.372902.348401.52110K562PSIP1
ERAP1ENSG00000164307.8799.628101140.65730-0.512505.874404.93630K562PTBP1
ERAP1ENSG00000164307.81478.228001973.39980-0.416804.034703.05420K562PUF60
ERAP1ENSG00000164307.83174.669802099.131600.5967011.307009.07960K562PUM1
ERAP1ENSG00000164307.83069.448202056.619700.5776012.5023010.46540K562PUM2
ERAP1ENSG00000164307.8815.000701093.86980-0.424603.610602.63900K562RBM22
ERAP1ENSG00000164307.81371.465201062.431900.368203.439201.93890K562RBM25
ERAP1ENSG00000164307.81093.28570860.307500.345602.034501.34000K562RPS19
ERAP1ENSG00000164307.81747.221501201.147700.540503.154801.45680K562RPS3A
ERAP1ENSG00000164307.81547.404201100.200300.492005.912604.75660K562SF3A3
ERAP1ENSG00000164307.81036.18240738.175700.489103.464202.37210K562SF3B1
ERAP1ENSG00000164307.8759.600701164.71230-0.616708.543606.99700K562SF3B4
ERAP1ENSG00000164307.8882.68870545.940800.693107.359305.32180K562SLBP
ERAP1ENSG00000164307.81010.89750769.789400.393003.369001.58900K562SND1
ERAP1ENSG00000164307.8775.854401118.20060-0.527305.807104.79070K562SRSF1
ERAP1ENSG00000164307.81073.81450864.763100.312303.001801.66030K562SSB
ERAP1ENSG00000164307.81815.637501312.884000.467604.575302.77600K562SSRP1
ERAP1ENSG00000164307.81699.396501200.758800.501004.599302.91350K562STAU1
ERAP1ENSG00000164307.82506.332901721.803000.541609.050206.57840K562SUCLG1
ERAP1ENSG00000164307.82078.216101234.360300.751503.262001.67300K562SUPT6H
ERAP1ENSG00000164307.8795.484201087.53660-0.451204.659003.58620K562SYNCRIP
ERAP1ENSG00000164307.8756.125501131.74320-0.581805.792004.74480K562TARDBP
ERAP1ENSG00000164307.81201.07880794.791200.595605.530704.16440K562TIAL1
ERAP1ENSG00000164307.82808.225302225.056800.335703.394701.82170K562UBE2L3
ERAP1ENSG00000164307.81163.17150865.481400.426403.161602.07010K562UCHL5
ERAP1ENSG00000164307.82358.875801182.305200.9964036.6355034.37700K562UPF1
ERAP1ENSG00000164307.81922.078001056.395900.8634011.538409.30140K562UTP3
ERAP1ENSG00000164307.81860.033301011.667000.8785017.3826015.19520K562WDR3
ERAP1ENSG00000164307.83004.130801556.698400.9484020.6084018.10380K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ERAP1 is not available on ENCORE database.





5 RBPs can affect the splicing of ERAP1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEERAP1ENSG00000164307.8chr5-9611298296113113961101879611225596116126961162080.102000.005540.08770includedK562U2AF1
SEERAP1ENSG00000164307.8chr5-961242339612438896122173961222539612599896126070-0.143000.006760.09109excludedK562U2AF2
A5SSERAP1ENSG00000164307.8chr5-961214919612167596121526961216759611962796119784-0.161000.000290.02070shorterHepG2SRSF1
MXEERAP1ENSG00000164307.8chr5-96129505961296609612968996129791961291029612921696130744961308650.175000.000380.009641includedHepG2U2AF1
MXEERAP1ENSG00000164307.8chr5-96129505961296609612968996129791961291029612921696130744961308650.084000.001940.026821includedK562U2AF2
MXEERAP1ENSG00000164307.8chr5-9612950596129660961296899612979196129102961292169613074496130865-0.081000.006490.057542includedHepG2SFPQ
MXEERAP1ENSG00000164307.8chr5-9612950596129660961296899612979196129102961292169613074496130865-0.080000.006720.077122includedHepG2HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ERAP1 is not avaliable on ENCORE database.