DARS

General Information

Gene Name       : DARS
Gene ID             : ENSG00000115866.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: DARS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DARSENSG00000115866.10123.51105.35114.43ENCSR000AEF
HepG2DARSENSG00000115866.1078.64109.4194.03ENCSR985KAT
K562DARSENSG00000115866.10101.73112.49107.11ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq DARS-BGHcLV29-HepG2ENCSR574ZTODARSHepG2ReleasedENCSR462MFN   CRISPRKD% = 51.2,54.2






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
DARSENCAB187BNVA304-799A1Released, ENCODE4BGHcLV29-57, Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
DARSK562CRISPRBGKcLV28-57,BGKcLV28-58BGKcLV28-1,BGKcLV28-238.7,41.0NotSatisfiedENCODE4
DARSK562CRISPRBGKcLV35-21,BGKcLV35-22BGKcLV35-1,BGKcLV35-20.0,0.0NotSatisfiedENCORE2
DARSHepG2CRISPRENCSR574ZTOENCSR462MFNDARS-BGHcLV29-57,DARS-BGHcLV29-58NT-BGHcLV29-1,NT-BGHcLV29-251.2,54.2ReleasedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
DARSProduct_ID: A304-799A
Lot_ID: 1
Source: Bethyl Labs
Target Name: DARS-human		 DARS1-HEPG2-CRISPR-A304-799A.png<br>Caption: Western blot following CRISPR against DARS in HepG2 whole cell lysate using DARS specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against DARS. DARS protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.
 Bethyl_A304-799A_1_DARS.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the DARS specific antibody, A304-799A. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the DARS-specific antibody, A304-799A. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.








RNA Targets

  • eCLIP assay for DARS is not avaliable on ENCORE database.



Proteins bound to RNA
  • DARS RNA is bound by 33 proteins.  







eCLIP assay for DARS is not avaliable on ENCORE database.





33 proteins are bound to DARS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2136664750136664799-3'-UTR,intron-Distal,intron-Proximal3.3252929.43653K562PABPC4
chr2136664432136664474-3'-UTR,intron-Distal4.040323.61881HepG2TIAL1
chr2136664799136664823-3'-UTR,intron-Distal,intron-Proximal4.200497.28182K562PABPC4
chr2136664285136664350-3'-UTR,intron-Distal,intron-Proximal4.3761911.46767HepG2SUB1
chr2136664546136664599-3'-UTR,intron-Distal3.457535.92362K562IGF2BP1
chr2136664612136664702-3'-UTR,intron-Distal6.7352715.75633HepG2SUB1
chr2136736842136736887-5'-UTR,CDS,intron-Distal,intron-Proximal3.3627920.39257HepG2BCLAF1
chr2136742972136742982-5'-UTR,CDS,intron-Distal4.089065.77244K562UCHL5
chr2136743068136743116-5'-UTR,CDS,intron-Distal,intron-Proximal3.7352923.30028K562DDX3X
chr2136742973136743113-5'-UTR,CDS,intron-Distal,intron-Proximal3.102557.92610HepG2UCHL5
chr2136736904136736932-5'-UTR,CDS,intron-Distal3.439654.37145K562GRWD1
chr2136736844136736930-5'-UTR,CDS,intron-Distal3.553949.44524HepG2G3BP1
chr2136736877136736937-5'-UTR,CDS,intron-Distal,intron-Proximal4.661423.98716K562IGF2BP1
chr2136736901136736934-5'-UTR,CDS,intron-Distal3.4651413.63814HepG2BCLAF1
chr2136719035136719068-5'-UTR,CDS,intron-Distal3.0622812.76800HepG2BCLAF1
chr2136740979136741008-5'-UTR,CDS,intron-Distal3.6121910.38320HepG2BCLAF1
chr2136718987136719035-5'-UTR,CDS,intron-Distal3.2705817.20879HepG2BCLAF1
chr2136719025136719072-5'-UTR,CDS,intron-Distal,intron-Proximal3.512223.39008HepG2AQR
chr2136736862136736894-5'-UTR,CDS,intron-Distal3.8187611.74413HepG2GRWD1
chr2136742941136742994-5'-UTR,CDS,intron-Distal3.785724.90219HepG2AQR
chr2136742972136742988-5'-UTR,CDS,intron-Distal3.098706.46814K562ZNF622
chr2136740966136741025-5'-UTR,CDS,intron-Distal,intron-Proximal3.024898.97671HepG2PPIG
chr2136740969136741019-5'-UTR,CDS,intron-Distal,intron-Proximal5.085487.18438HepG2G3BP1
chr2136742973136743068-5'-UTR,CDS,intron-Distal,intron-Proximal3.7926246.73601K562DDX3X
chr2136719060136719068-5'-UTR,CDS,intron-Distal3.288776.56666K562YBX3
chr2136743116136743170-5'-UTR,CDS,intron-Distal,intron-Proximal4.109956.42503K562DDX3X
chr2136740968136741024-5'-UTR,CDS,intron-Distal,intron-Proximal3.6659710.63268K562UCHL5
chr2136736847136736862-5'-UTR,CDS,intron-Distal3.002366.95311HepG2GRWD1
chr2136743003136743130-5'-UTR,CDS,intron-Distal,intron-Proximal3.6799419.89620K562GEMIN5
chr2136670055136670100-CDS,intron-Distal,intron-Proximal4.0065614.72858HepG2BCLAF1
chr2136664894136664933-CDS,intron-Distal3.736255.14242HepG2G3BP1
chr2136690316136690385-CDS,intron-Distal,intron-Proximal4.515198.47339HepG2PRPF8
chr2136690406136690412-CDS,intron-Distal3.8934711.16705K562UCHL5
chr2136670059136670114-CDS,intron-Distal3.0370216.00000K562YBX3
chr2136691507136691556-CDS,intron-Distal3.0123118.06214HepG2BCLAF1
chr2136691479136691558-CDS,intron-Distal,intron-Proximal3.351249.24847K562ZNF800
chr2136678048136678074-CDS,intron-Distal3.313145.96568HepG2GRWD1
chr2136673796136673883-CDS,intron-Distal3.1552325.09415HepG2BCLAF1
chr2136672060136672081-CDS,intron-Distal4.626376.53064K562GRWD1
chr2136669047136669063-CDS,intron-Distal3.189904.96885HepG2G3BP1
chr2136678032136678047-CDS,intron-Distal4.4228415.99938HepG2BCLAF1
chr2136691479136691513-CDS,intron-Distal,intron-Proximal3.009958.02644HepG2G3BP1
chr2136673839136673891-CDS,intron-Distal3.095197.78685HepG2GRWD1
chr2136678021136678075-CDS,intron-Distal,intron-Proximal4.555973.50232K562IGF2BP1
chr2136673911136673941-CDS,intron-Distal3.4345912.00921HepG2BCLAF1
chr2136678139136678159-CDS,intron-Distal,intron-Proximal3.586618.52291HepG2G3BP1
chr2136691479136691484-CDS,intron-Distal,intron-Proximal4.3653411.98560K562UCHL5
chr2136690382136690405-CDS,intron-Distal4.2015515.77730K562UCHL5
chr2136678159136678171-CDS,intron-Distal,intron-Proximal3.347698.09984HepG2G3BP1
chr2136690353136690392-CDS,intron-Distal3.797585.37552K562PUM1
chr2136690361136690419-CDS,intron-Distal,intron-Proximal3.558359.57460K562GPKOW
chr2136680405136680448-CDS,intron-Distal5.038517.77669HepG2G3BP1
chr2136673795136673864-CDS,intron-Distal,intron-Proximal3.4255510.95121HepG2G3BP1
chr2136681956136681965-CDS,intron-Distal,intron-Proximal3.215078.02162HepG2BCLAF1
chr2136678098136678122-CDS,intron-Distal3.321419.03865HepG2BCLAF1
chr2136690276136690374-CDS,intron-Distal,intron-Proximal3.022944.90577K562EFTUD2
chr2136678047136678098-CDS,intron-Distal4.0652920.67097HepG2BCLAF1
chr2136673795136673856-CDS,intron-Distal,intron-Proximal3.594478.23581K562RPS3
chr2136691484136691518-CDS,intron-Distal3.7912117.08805K562UCHL5
chr2136673888136673942-CDS,intron-Distal4.715603.98311K562IGF2BP1
chr2136673800136673866-CDS,intron-Distal3.478529.05790HepG2RPS3
chr2136668771136668780-CDS,intron-Distal3.079387.37965K562YBX3
chr2136680464136680488-CDS,intron-Distal3.134518.30744HepG2BCLAF1
chr2136672069136672081-CDS,intron-Distal4.827956.29942HepG2G3BP1
chr2136672020136672126-CDS,intron-Distal,intron-Proximal4.5986416.70946K562SF3B4
chr2136668711136668748-CDS,intron-Distal3.117773.28075K562GRWD1
chr2136682055136682068-CDS,intron-Distal4.656345.50717HepG2G3BP1
chr2136668951136668978-CDS,intron-Distal,intron-Proximal3.071868.24506K562YBX3
chr2136690349136690387-CDS,intron-Distal,intron-Proximal3.2878612.58970HepG2BCLAF1
chr2136680402136680443-CDS,intron-Distal3.4819412.03080HepG2BCLAF1
chr2136682011136682055-CDS,intron-Distal3.736468.54875HepG2G3BP1
chr2136700950136700982-CDS,intron-Distal,intron-Proximal3.372774.41873K562ZNF800
chr2136681972136681978-CDS,intron-Distal,intron-Proximal4.256607.16838HepG2BCLAF1
chr2136690370136690413-CDS,intron-Distal,intron-Proximal3.000236.95507HepG2G3BP1
chr2136669046136669063-CDS,intron-Distal3.7592110.10467HepG2BCLAF1
chr2136678022136678032-CDS,intron-Distal,intron-Proximal4.5444417.22692HepG2BCLAF1
chr2136678074136678094-CDS,intron-Distal3.596635.31167HepG2GRWD1
chr2136683119136683195-intron-Distal3.487975.39573HepG2KHSRP
chr2136731856136731939-intron-Distal4.312368.60427HepG2CSTF2
chr2136682160136682218-intron-Distal,intron-Proximal3.859097.07404HepG2U2AF2
chr2136729945136730021-intron-Distal3.212093.46325HepG2SUGP2
chr2136731860136731942-intron-Distal4.176614.48935K562CSTF2T
chr2136684377136684445-intron-Distal4.9162321.92778HepG2QKI
chr2136687299136687339-intron-Distal3.661463.19036K562HNRNPL
chr2136684903136684953-intron-Distal5.040147.27881HepG2KHSRP
chr2136683036136683081-intron-Distal3.095034.64228HepG2KHSRP
chr2136683218136683280-intron-Distal3.512785.14864K562KHSRP
chr2136682493136682544-intron-Distal3.153365.98045K562KHSRP
chr2136682366136682454-intron-Distal3.067543.03131K562HNRNPL
chr2136684485136684576-intron-Distal3.2215211.13262K562KHSRP
chr2136683166136683192-intron-Distal4.307645.46313K562KHSRP
chr2136684741136684802-intron-Distal4.3011115.06734K562KHSRP
chr2136682220136682269-intron-Distal5.3463519.74910K562KHSRP
chr2136685547136685634-intron-Distal3.440284.99653HepG2CSTF2
chr2136683192136683218-intron-Distal4.213835.19823K562KHSRP
chr2136742938136742962-intron-Distal4.976194.02817HepG2PRPF8
chr2136742841136742961-intron-Distal4.078548.63083HepG2PRPF4
chr2136684686136684783-intron-Distal3.7735517.41789HepG2KHSRP
chr2136673486136673586-intron-Distal3.489788.44889K562KHSRP
chr2136690271136690329-intron-Distal,intron-Proximal5.132165.56495HepG2RBM22
chr2136703811136703885-intron-Distal4.869395.96444HepG2PCBP2
chr2136673397136673465-intron-Distal3.211364.18806HepG2U2AF2
chr2136684375136684451-intron-Distal5.0053915.63398K562QKI
chr2136684472136684555-intron-Distal3.6547410.39508HepG2U2AF2
chr2136700632136700735-intron-Distal,intron-Proximal3.237003.51804HepG2HNRNPL
chr2136695972136696074-intron-Distal4.291073.89826HepG2BCLAF1
chr2136684681136684741-intron-Distal4.8694116.87092K562KHSRP
chr2136684810136684892-intron-Distal3.7790310.34114K562KHSRP
chr2136682405136682477-intron-Distal3.083035.57010K562KHSRP
chr2136683113136683138-intron-Distal4.653427.39957K562KHSRP
chr2136673354136673571-intron-Distal3.8671911.54555HepG2KHSRP
chr2136684299136684377-intron-Distal5.8754242.84395HepG2QKI
chr2136684986136685029-intron-Distal3.301914.13575K562KHSRP
chr2136684422136684465-intron-Distal3.796324.77518HepG2U2AF2
chr2136742406136742472-intron-Distal4.107413.93804HepG2U2AF1
chr2136684598136684656-intron-Distal3.249496.18258HepG2U2AF2
chr2136684315136684374-intron-Distal6.7968918.92750K562QKI
chr2136682159136682220-intron-Distal,intron-Proximal4.5653423.37872K562KHSRP
chr2136673363136673471-intron-Distal3.365835.57010K562KHSRP
chr2136708389136708503-intron-Distal4.013823.31570HepG2HNRNPK
chr2136695093136695178-intron-Distal4.530344.34038HepG2BCLAF1
chr2136684892136684969-intron-Distal4.4680016.19264K562KHSRP
chr2136683138136683166-intron-Distal4.989519.48201K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DARS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DARS is not available on ENCORE database.

  • 130 RBPs can affect the levels of DARS.  








The Knockdown/knockout RNA-Seq assay for DARS is not available on ENCORE database.





130 RBPs can affect the gene expression of DARS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DARSENSG00000115866.63103.886103773.68970-0.281905.179504.39940HepG2ACO1
DARSENSG00000115866.66609.449408249.44060-0.319802.165401.68840HepG2AKAP1
DARSENSG00000115866.63334.411803791.23880-0.185202.193701.50170HepG2AKAP8L
DARSENSG00000115866.64887.466606825.78600-0.481905.174004.11700HepG2ASCC1
DARSENSG00000115866.64783.277705634.79930-0.236402.916202.21440HepG2AUH
DARSENSG00000115866.62155.104603412.53370-0.663106.949405.42580HepG2BCCIP
DARSENSG00000115866.62287.284202965.27770-0.374502.832401.92350HepG2BCLAF1
DARSENSG00000115866.62138.566302883.73910-0.431302.752602.15570HepG2BOP1
DARSENSG00000115866.65301.780606484.94510-0.290602.269901.56450HepG2CIRBP
DARSENSG00000115866.62814.613803772.65220-0.4226012.0009010.81380HepG2CKAP4
DARSENSG00000115866.63188.839504621.18090-0.535203.379102.52740HepG2CNOT7
DARSENSG00000115866.61628.410302107.97380-0.372403.105301.97090HepG2CSTF2
DARSENSG00000115866.64106.881005514.60190-0.425209.274208.22630HepG2CELF1
DARSENSG00000115866.65106.799305929.79480-0.215604.318103.42550HepG2DAZAP1
DARSENSG00000115866.61573.821003500.12190-1.1531030.5787028.68840HepG2DDX21
DARSENSG00000115866.65103.315207902.48270-0.630908.164807.14140HepG2DDX3X
DARSENSG00000115866.62353.859403355.20200-0.511404.474303.51500HepG2DDX55
DARSENSG00000115866.65025.081206788.06000-0.433903.695602.99010HepG2DDX6
DARSENSG00000115866.62578.948403610.34220-0.4854011.5510010.36520HepG2DKC1
DARSENSG00000115866.62168.533903329.03520-0.6184022.8784021.16340HepG2DNAJC2
DARSENSG00000115866.62413.503103529.01390-0.548103.205002.21880HepG2EEF2
DARSENSG00000115866.63691.567406525.86040-0.8219013.3952012.15890HepG2EIF2S1
DARSENSG00000115866.62247.299502810.46490-0.322603.529202.20660HepG2EIF2S2
DARSENSG00000115866.62628.225503304.80140-0.330503.846702.59980HepG2EIF3G
DARSENSG00000115866.64226.907307212.00420-0.770809.987008.78960HepG2EIF4A3
DARSENSG00000115866.63813.297807021.59020-0.8808010.144808.86990HepG2EIF4B
DARSENSG00000115866.64661.525006469.32050-0.4728013.0731011.92460HepG2ETF1
DARSENSG00000115866.63010.393503687.37620-0.292602.907302.05300HepG2EWSR1
DARSENSG00000115866.62879.754603741.22230-0.377603.041302.23810HepG2FIP1L1
DARSENSG00000115866.63031.462904192.43700-0.467802.874101.73720HepG2FUS
DARSENSG00000115866.64403.525707276.12170-0.7245010.903809.61910HepG2FXR1
DARSENSG00000115866.63130.452706749.92660-1.1085021.0948019.33510HepG2G3BP1
DARSENSG00000115866.65379.229307165.57690-0.413704.141603.04290HepG2G3BP2
DARSENSG00000115866.61818.824802550.98800-0.488003.113802.15920HepG2GEMIN5
DARSENSG00000115866.62910.041204051.03000-0.477204.312003.03370HepG2GNB2L1
DARSENSG00000115866.62958.099004277.70370-0.532203.701902.40980HepG2GRSF1
DARSENSG00000115866.61929.836203390.93110-0.8132016.2714014.91500HepG2HNRNPA1
DARSENSG00000115866.62534.447203771.76400-0.573608.597607.42820HepG2HNRNPC
DARSENSG00000115866.65252.156606834.31270-0.379904.020203.19220HepG2HNRNPK
DARSENSG00000115866.64856.488005401.66320-0.153502.585701.93300HepG2HNRNPL
DARSENSG00000115866.62737.496603746.82890-0.4528010.965209.82520HepG2HNRNPU
DARSENSG00000115866.62719.274503643.80890-0.422202.879301.61960HepG2HSPD1
DARSENSG00000115866.62167.419406861.24430-1.6625050.4065047.96990HepG2IGF2BP2
DARSENSG00000115866.63528.438106438.61370-0.867704.501703.25690HepG2IGF2BP3
DARSENSG00000115866.63137.105103827.26510-0.286906.347105.28190HepG2ILF2
DARSENSG00000115866.64838.174606901.06850-0.512404.168202.91640HepG2KHSRP
DARSENSG00000115866.62606.496803640.54080-0.482003.178901.83480HepG2KRR1
DARSENSG00000115866.63099.183405619.55910-0.8586010.128308.54260HepG2LARP4
DARSENSG00000115866.63263.402907278.65980-1.1573024.7947022.96140HepG2MAGOH
DARSENSG00000115866.63874.858507319.47700-0.9176014.3985013.04080HepG2MATR3
DARSENSG00000115866.61982.804402998.65380-0.596803.679002.47100HepG2METAP2
DARSENSG00000115866.62379.279203027.67990-0.347703.900402.94420HepG2MSI2
DARSENSG00000115866.63133.143907491.95620-1.2577027.6929025.84130HepG2NCBP2
DARSENSG00000115866.61784.647103080.80980-0.787705.176303.65720HepG2NONO
DARSENSG00000115866.63761.343802539.548300.566605.862504.79790HepG2NSUN2
DARSENSG00000115866.64956.687306672.37220-0.428804.011603.15290HepG2PABPC4
DARSENSG00000115866.63104.264103708.74400-0.256703.770002.79880HepG2PARN
DARSENSG00000115866.63676.583106688.67820-0.8634040.7901038.95460HepG2PCBP1
DARSENSG00000115866.61747.165602369.24710-0.439403.124001.81530HepG2PKM
DARSENSG00000115866.61828.855102165.77010-0.243902.824602.04500HepG2PRPF4
DARSENSG00000115866.62035.635302588.42150-0.346602.511601.74050HepG2PRPF8
DARSENSG00000115866.63169.028306806.20750-1.1028062.3888060.58360HepG2PTBP1
DARSENSG00000115866.64184.903605612.86790-0.423505.748904.93100HepG2PUF60
DARSENSG00000115866.63399.993305958.22750-0.8094050.9622049.06760HepG2PUM1
DARSENSG00000115866.64228.660405953.92480-0.493609.417208.21730HepG2PUM2
DARSENSG00000115866.62524.424003843.71590-0.6065020.7557019.35150HepG2PUS1
DARSENSG00000115866.65030.918807370.80640-0.5510012.6890011.49250HepG2QKI
DARSENSG00000115866.64069.025605407.19300-0.410208.073907.29730HepG2RBM22
DARSENSG00000115866.65236.114506689.66360-0.353404.360203.52960HepG2RBM25
DARSENSG00000115866.63099.006904784.66600-0.626606.757805.20290HepG2RBM27
DARSENSG00000115866.64005.060407574.46660-0.9193046.4795044.88050HepG2NELFE
DARSENSG00000115866.64373.633607054.92890-0.6898027.7307026.14050HepG2RECQL
DARSENSG00000115866.61182.923702787.56040-1.2366013.5891012.35920HepG2RPS19
DARSENSG00000115866.62423.516604412.96980-0.8646013.0980011.45980HepG2RPS2
DARSENSG00000115866.62565.083404639.51700-0.855009.542408.08640HepG2RPS3A
DARSENSG00000115866.61565.416802798.09510-0.837906.263404.86210HepG2SERBP1
DARSENSG00000115866.62453.186103762.40460-0.617004.819603.91450HepG2SF3A3
DARSENSG00000115866.63688.736707085.73290-0.9418049.1416047.24900HepG2SF3B4
DARSENSG00000115866.62386.630003891.20910-0.7052034.1074032.27720HepG2SMN1
DARSENSG00000115866.61634.311003902.75270-1.2558015.8553013.50470HepG2SMNDC1
DARSENSG00000115866.66717.709806107.293000.137302.040401.58970HepG2SRFBP1
DARSENSG00000115866.63472.161407396.13750-1.0909072.9484071.27940HepG2SRSF1
DARSENSG00000115866.63313.746105541.79410-0.7419029.8591028.10680HepG2SRSF5
DARSENSG00000115866.64440.247206017.29510-0.4385012.3744011.35410HepG2SRSF9
DARSENSG00000115866.63471.307205302.69420-0.6112015.9674014.94390HepG2SSB
DARSENSG00000115866.62882.765404035.57890-0.485303.648102.36800HepG2STIP1
DARSENSG00000115866.64413.439406302.62830-0.5141019.4869018.07540HepG2SUCLG1
DARSENSG00000115866.62112.734703340.09660-0.660807.256906.24460HepG2SUPV3L1
DARSENSG00000115866.64566.545806648.39840-0.5419013.2062012.11800HepG2TAF15
DARSENSG00000115866.6928.250502791.16870-1.5883019.5555017.94910HepG2TARDBP
DARSENSG00000115866.62130.113403565.02440-0.743003.698702.47270HepG2TBRG4
DARSENSG00000115866.61672.180202238.77690-0.421003.266602.18790HepG2TFIP11
DARSENSG00000115866.64955.916106108.48260-0.301703.340902.42620HepG2TIA1
DARSENSG00000115866.61719.514803640.81890-1.0823035.9777034.54780HepG2TIAL1
DARSENSG00000115866.62653.142403845.49170-0.535503.808802.09710HepG2TRA2A
DARSENSG00000115866.62289.814503673.28520-0.6818023.1999021.76590HepG2TRIM56
DARSENSG00000115866.63755.485705483.40430-0.546109.824807.98890HepG2TUFM
DARSENSG00000115866.62627.014903200.24680-0.284802.403201.81420HepG2U2AF1
DARSENSG00000115866.64516.262505804.01170-0.361903.157502.26360HepG2UBE2L3
DARSENSG00000115866.61100.277501973.12840-0.8426011.9040010.34670HepG2UCHL5
DARSENSG00000115866.62852.297903336.68320-0.226303.312202.55910HepG2UPF1
DARSENSG00000115866.62014.040903058.62360-0.602804.139602.90040HepG2UPF2
DARSENSG00000115866.62369.828803221.42810-0.4429010.069209.03970HepG2UTP3
DARSENSG00000115866.62276.967403287.95740-0.530105.598604.57910HepG2XRN2
DARSENSG00000115866.61373.407202137.31190-0.6380018.6153017.14610HepG2ZC3H8
DARSENSG00000115866.64803.751904284.012600.165102.160501.64840K562AGGF1
DARSENSG00000115866.65865.766307122.39690-0.280002.680701.45960K562APOBEC3C
DARSENSG00000115866.63576.685907152.87210-0.9999023.9055022.36810K562AQR
DARSENSG00000115866.64804.587406509.20150-0.438102.359401.39180K562CNOT7
DARSENSG00000115866.64924.302505668.23090-0.203002.435201.40180K562CPEB4
DARSENSG00000115866.63053.081504411.61020-0.531007.843106.51140K562CPSF6
DARSENSG00000115866.63162.852203986.72680-0.334003.649102.43110K562DDX3X
DARSENSG00000115866.62537.021003308.42910-0.383003.377602.36510K562EFTUD2
DARSENSG00000115866.63220.571304214.77790-0.388107.223806.14230K562EIF2S2
DARSENSG00000115866.62757.139103542.58990-0.361602.465301.49520K562EIF3D
DARSENSG00000115866.62539.873704165.22560-0.7136012.6155010.82120K562EIF4A3
DARSENSG00000115866.63023.837403751.08830-0.310903.977002.54620K562EIF4B
DARSENSG00000115866.64805.659504008.230200.261702.153301.40290K562FIP1L1
DARSENSG00000115866.63656.200704488.69480-0.296002.521201.70550K562FMR1
DARSENSG00000115866.62478.296404331.67320-0.8056027.1087025.34020K562FXR1
DARSENSG00000115866.65417.725404255.134000.348402.127301.51930K562G3BP2
DARSENSG00000115866.63253.512604212.00780-0.372504.226303.25060K562GPKOW
DARSENSG00000115866.61801.171803713.72370-1.0439028.5487026.71550K562HNRNPC
DARSENSG00000115866.62553.652503316.33570-0.377004.243302.79390K562HNRNPF
DARSENSG00000115866.64378.230205300.25490-0.275702.588401.56840K562HNRNPL
DARSENSG00000115866.63486.783705438.21270-0.641206.999705.06440K562IGF2BP2
DARSENSG00000115866.62916.605803596.19120-0.302202.842601.43410K562LARP7
DARSENSG00000115866.63742.193505717.42440-0.611508.915407.36150K562MAGOH
DARSENSG00000115866.64642.839705706.14130-0.297502.666401.76090K562MATR3
DARSENSG00000115866.63356.636504111.38720-0.292602.760601.88500K562METAP2
DARSENSG00000115866.63553.635404011.94730-0.175002.233901.50330K562MTPAP
DARSENSG00000115866.64031.461804457.52610-0.144902.406101.70570K562NSUN2
DARSENSG00000115866.62752.898303656.47880-0.409503.472201.80990K562NUSAP1
DARSENSG00000115866.64059.523505087.47110-0.325602.804801.81930K562PCBP2
DARSENSG00000115866.65841.597908294.17550-0.505709.042606.72290K562PNPT1
DARSENSG00000115866.61738.934502291.04800-0.397804.977803.89940K562POLR2G
DARSENSG00000115866.62441.632203219.47570-0.399003.723502.85290K562PRPF8
DARSENSG00000115866.62340.189603329.73560-0.508806.376904.91400K562PSIP1
DARSENSG00000115866.63577.854005554.68070-0.634609.629508.44510K562PTBP1
DARSENSG00000115866.66035.336208806.96910-0.545208.441207.00730K562PUF60
DARSENSG00000115866.67535.174309178.35970-0.284604.835003.55250K562PUM2
DARSENSG00000115866.65219.807404420.671600.239601.970701.49760K562PUS1
DARSENSG00000115866.65148.129704307.425700.257103.369402.72480K562RBM15
DARSENSG00000115866.63494.593905327.41000-0.608307.157105.72660K562RBM22
DARSENSG00000115866.62438.728803037.91980-0.317003.377502.28300K562RCC2
DARSENSG00000115866.64553.117903291.988700.467803.512901.99860K562RRP9
DARSENSG00000115866.63746.625404398.60080-0.231502.744901.93300K562SF3A3
DARSENSG00000115866.62950.364404424.59600-0.5847011.674109.84090K562SF3B4
DARSENSG00000115866.62185.978302879.87010-0.397704.152602.82180K562SRFBP1
DARSENSG00000115866.63762.955004506.47590-0.260105.090603.86740K562SRPK2
DARSENSG00000115866.62648.977005445.20590-1.0396021.0390019.10760K562SRSF1
DARSENSG00000115866.61540.645702186.32040-0.505005.982704.32780K562SRSF4
DARSENSG00000115866.62714.256803285.79000-0.275703.601602.25440K562SRSF7
DARSENSG00000115866.62445.016103117.49130-0.350502.484801.52680K562SUPV3L1
DARSENSG00000115866.61871.993902297.90320-0.295702.983502.12660K562SYNCRIP
DARSENSG00000115866.64168.988605511.40590-0.402704.097903.23150K562TARDBP
DARSENSG00000115866.64304.043905316.24140-0.304703.087702.21450K562TIA1
DARSENSG00000115866.62600.919403202.65270-0.300202.116601.30930K562TIAL1
DARSENSG00000115866.63260.175304124.61330-0.339302.471601.44780K562U2AF1
DARSENSG00000115866.63184.212004259.82590-0.419906.328505.12270K562U2AF2
DARSENSG00000115866.63453.308104726.41800-0.4528012.1776010.80340K562UPF1
DARSENSG00000115866.62586.261203359.34810-0.377303.217101.87920K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DARS is not available on ENCORE database.





7 RBPs can affect the splicing of DARS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDARSENSG00000115866.6chr2-136736843136736936136718965136719068136742972136743062-0.069000.000000.00022excludedK562SF3B4
SEDARSENSG00000115866.6chr2-136670055136670136136668951136669063136672038136672081-0.058000.000000.00000excludedHepG2U2AF1
SEDARSENSG00000115866.6chr2-136670055136670136136668951136669063136672038136672081-0.068000.000000.00000excludedHepG2U2AF2
SEDARSENSG00000115866.6chr2-136740966136741024136718965136719068136742972136743254-0.070000.000360.00731excludedK562PUS1
SEDARSENSG00000115866.6chr2-136670055136670136136668951136669063136672038136672081-0.051000.000000.00000excludedK562U2AF1
SEDARSENSG00000115866.6chr2-136690352136690408136681956136682068136691479136691560-0.061000.000090.00339excludedHepG2SRSF1
SEDARSENSG00000115866.6chr2-136740966136741024136718965136719068136742972136743254-0.153000.000030.00095excludedK562U2AF2
SEDARSENSG00000115866.6chr2-136670055136670136136668951136669063136672038136672081-0.057000.000000.00000excludedK562TARDBP
MXEDARSENSG00000115866.6chr2-1366832631366833971366880511366881691366819561366820681366903521366904120.391000.014960.087431includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DARS is not avaliable on ENCORE database.