CSE1L

General Information

Gene Name : CSE1L
Gene ID : ENSG00000124207.16
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CSE1L)

Not Available

Antibody Validation

View validation images for all CSE1L antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CSE1L	ENSG00000124207.16	95.84	89.18	92.51	ENCSR000AEF
HepG2	CSE1L	ENSG00000124207.16	112.00	219.29	165.64	ENCSR985KAT
K562	CSE1L	ENSG00000124207.16	146.43	171.30	158.87	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	CSE1L-BGKcLV28-K562	ENCSR877CJJ	CSE1L	K562	Released		ENCSR220DTX	CRISPR	KD% = 73.9,78.9

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CSE1L	ENCAB024AVF	A300-473A	2			Released, ENCODE4	BGHcLV34-15, Released, ENCODE4	BGKcLV28-43, Released, ENCODE4
CSE1L	ENCAB578YRG	A300-472A	2			Released, ENCODE4	BGHcLV34-15, Released, ENCODE4	BGKcLV28-43, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
CSE1L	K562	CRISPR	ENCSR877CJJ	ENCSR220DTX	CSE1L-BGKcLV28-43,CSE1L-BGKcLV28-44	NT-BGKcLV28-1,NT-BGKcLV28-2	73.9,78.9	Released	ENCODE4
CSE1L	HepG2	CRISPR			BGHcLV29-43,BGHcLV29-44	BGHcLV29-1,BGHcLV29-2	32.7,34.2	NotSatisfied	ENCODE4
CSE1L	HepG2	CRISPR			CSE1L-BGHcLV34-15,CSE1L-BGHcLV34-16	NT-BGHcLV34-1,NT-BGHcLV34-2	52.0,60.8	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CSE1L	Product_ID: A300-472A Lot_ID: 2 Source: Bethyl Labs Target Name: CSE1L-human
CSE1L	Product_ID: A300-473A Lot_ID: 2 Source: Bethyl Labs Target Name: CSE1L-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CSE1L is not avaliable on ENCORE database.

Proteins bound to RNA

CSE1L RNA is bound by 34 proteins.

CanvasJS.com

eCLIP assay for CSE1L is not avaliable on ENCORE database.

34 proteins are bound to CSE1L RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr20	47705840	47705921	+	CDS	4.77159	84.73485	K562	PUM2
chr20	47662913	47662954	+	5'-UTR	4.15694	38.66456	K562	DDX3X
chr20	47674989	47675041	+	5'-UTR,CDS,intron-Proximal	4.49504	36.71963	K562	DDX3X
chr20	47691991	47692022	+	CDS	4.33532	33.98586	K562	YBX3
chr20	47662954	47662961	+	5'-UTR,intron-Proximal	4.12844	30.53347	K562	DDX3X
chr20	47692022	47692027	+	CDS	4.45346	30.37915	K562	YBX3
chr20	47711252	47711312	+	CDS,intron-Proximal	3.53408	26.50118	HepG2	U2AF2
chr20	47682977	47683047	+	CDS,intron-Distal	5.56575	26.33504	K562	LIN28B
chr20	47691985	47691991	+	CDS	4.44093	24.84269	K562	YBX3
chr20	47662864	47662958	+	5'-UTR	5.18101	23.23109	K562	GEMIN5
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 138 entries

eCLIP assay for CSE1L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CSE1L is not available on ENCORE database.
143 RBPs can affect the levels of CSE1L.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CSE1L is not available on ENCORE database.

143 RBPs can affect the gene expression of CSE1L :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CSE1L	ENSG00000124207.12	1633.45370	5580.13060	-1.77240	201.33600	198.79540	HepG2	ZNF622
CSE1L	ENSG00000124207.12	12193.03200	3771.59580	1.69270	185.00030	182.74410	HepG2	SRSF1
CSE1L	ENSG00000124207.12	1447.92210	7083.27040	-2.29040	129.22750	125.97270	HepG2	PUF60
CSE1L	ENSG00000124207.12	2798.41410	7011.33310	-1.32510	90.77300	88.21110	HepG2	SRSF7
CSE1L	ENSG00000124207.12	2479.64210	4849.76120	-0.96780	60.57790	58.44990	HepG2	CKAP4
CSE1L	ENSG00000124207.12	2580.18220	8775.93050	-1.76610	57.05170	54.57850	HepG2	CPSF6
CSE1L	ENSG00000124207.12	1970.67210	5570.16250	-1.49900	54.46140	52.77290	HepG2	TIAL1
CSE1L	ENSG00000124207.12	2891.37950	7687.78890	-1.41080	49.48050	47.46820	HepG2	RPLP0
CSE1L	ENSG00000124207.12	3712.03470	7136.43290	-0.94300	47.54520	45.25660	HepG2	HNRNPF
CSE1L	ENSG00000124207.12	4694.78680	8305.62620	-0.82300	46.28480	44.88970	HepG2	SRFBP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 180 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CSE1L is not available on ENCORE database.

19 RBPs can affect the splicing of CSE1L :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	CSE1L	ENSG00000124207.12	chr20	+	47712712	47712737	47711268	47711500	47712885	47713123	0.13200	0.00000	included	K562	SF3B4
SE	CSE1L	ENSG00000124207.12	chr20	+	47711014	47711151	47710676	47710823	47711268	47711500	0.16800	0.00000	included	K562	SF3B4
SE	CSE1L	ENSG00000124207.12	chr20	+	47704545	47704643	47700562	47700699	47705783	47705934	-0.07800	0.00000	excluded	K562	SF3B4
SE	CSE1L	ENSG00000124207.12	chr20	+	47712712	47712764	47711268	47711500	47712885	47713123	0.09100	0.00000	included	K562	PRPF8
SE	CSE1L	ENSG00000124207.12	chr20	+	47701819	47701923	47700562	47700699	47704545	47704643	-0.09200	0.00000	excluded	HepG2	U2AF1
SE	CSE1L	ENSG00000124207.12	chr20	+	47701819	47701923	47700562	47700699	47704545	47704643	-0.09400	0.00000	excluded	HepG2	U2AF2
SE	CSE1L	ENSG00000124207.12	chr20	+	47701819	47701923	47700536	47700699	47704545	47704643	-0.05400	0.00000	excluded	K562	AQR
SE	CSE1L	ENSG00000124207.12	chr20	+	47708538	47708664	47707473	47707559	47710676	47710823	-0.07800	0.00000	excluded	K562	AQR
SE	CSE1L	ENSG00000124207.12	chr20	+	47691263	47691387	47689104	47689234	47691854	47692057	-0.05500	0.00007	excluded	K562	AQR
SE	CSE1L	ENSG00000124207.12	chr20	+	47701819	47701977	47700562	47700699	47704545	47704643	-0.09600	0.00040	excluded	HepG2	SRSF7

Showing 1 to 10 of 57 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CSE1L

General Information

Functions

Localization

Domains (AlphaFold: CSE1L)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CSE1L is not avaliable on ENCORE database.

34 proteins are bound to CSE1L RNA:

eCLIP assay for CSE1L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CSE1L is not available on ENCORE database.

143 RBPs can affect the gene expression of CSE1L :

The Knockdown/knockout RNA-Seq assay for CSE1L is not available on ENCORE database.

19 RBPs can affect the splicing of CSE1L :

The Knockdown/knockout RNA-Seq assay for CSE1L is not avaliable on ENCORE database.