UBB

General Information

Gene Name       : UBB
Gene ID             : ENSG00000170315.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: UBB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UBBENSG00000170315.131023.541111.061067.30ENCSR000AEF
HepG2UBBENSG00000170315.131738.661132.471435.57ENCSR985KAT
K562UBBENSG00000170315.131214.121292.881253.50ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for UBB is not avaliable on ENCORE database.



Proteins bound to RNA
  • UBB RNA is bound by 25 proteins.  







eCLIP assay for UBB is not avaliable on ENCORE database.





25 proteins are bound to UBB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr171628591016285950+3'-UTR4.9344722.38440K562RPS3
chr171628521516285220+3'-UTR,5'-UTR,intron-Distal,intron-Proximal5.7949166.23345HepG2SUB1
chr171628522016285249+3'-UTR,5'-UTR,CDS,intron-Distal5.4294768.08923HepG2SUB1
chr171628596216285988+3'-UTR3.441879.22394K562PABPC4
chr171628602816286056+3'-UTR,polyA_site4.503349.25286K562PUM2
chr171628590516285987+3'-UTR,CDS4.4216740.50268HepG2LARP4
chr171628521516285219+3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.7121310.17067K562NOLC1
chr171628521916285230+3'-UTR,5'-UTR,CDS,intron-Distal3.440748.54964K562NOLC1
chr171628591016285958+3'-UTR3.511517.09494HepG2DDX55
chr171628590316285950+3'-UTR,CDS4.120437.49320HepG2G3BP1
chr171628521516285228+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.3589670.34863K562DDX3X
chr171628590816285962+3'-UTR3.6147829.97749K562PABPC4
chr171628589816285956+3'-UTR,CDS3.6251510.16698K562LIN28B
chr171628446116284470+5'-UTR,intron-Distal8.35341400.00000HepG2SUB1
chr171628446816284482+5'-UTR,intron-Distal4.08601400.00000K562DDX3X
chr171628460216284658+5'-UTR,intron-Distal5.6019110.90062HepG2FAM120A
chr171628465316284712+5'-UTR,intron-Distal4.469844.70168K562CSTF2T
chr171628440916284497+5'-UTR,intron-Distal,intron-Proximal3.8508236.29943K562RPS3
chr171628449516284499+5'-UTR,intron-Distal,intron-Proximal3.70905400.00000K562DDX3X
chr171628442916284434+5'-UTR,intron-Proximal5.9732744.37379K562NOLC1
chr171628461916284664+5'-UTR,intron-Distal4.432234.99324HepG2GTF2F1
chr171628446216284470+5'-UTR,intron-Distal5.54549400.00000K562NOLC1
chr171628441516284499+5'-UTR,intron-Distal,intron-Proximal4.2790764.91332K562GEMIN5
chr171628447016284477+5'-UTR,intron-Distal8.01453400.00000HepG2SUB1
chr171628466416284708+5'-UTR,intron-Distal3.533044.99558HepG2GTF2F1
chr171628459416284660+5'-UTR,intron-Distal,intron-Proximal3.505114.84557HepG2CSTF2T
chr171628448716284493+5'-UTR,intron-Distal4.3396533.90960K562NOLC1
chr171628441116284500+5'-UTR,intron-Distal,intron-Proximal3.1214012.26551HepG2DDX3X
chr171628440716284495+5'-UTR,intron-Distal,intron-Proximal3.1649411.50999K562EIF3G
chr171628465816284718+5'-UTR,intron-Distal4.5776610.17684HepG2FAM120A
chr171628442516284461+5'-UTR,intron-Distal,intron-Proximal7.48501400.00000HepG2SUB1
chr171628448816284493+5'-UTR,intron-Distal9.06157400.00000HepG2SUB1
chr171628447716284484+5'-UTR,intron-Distal8.41339400.00000HepG2SUB1
chr171628456716284712+5'-UTR,intron-Distal,intron-Proximal4.4904211.11720HepG2PRPF4
chr171628448016284487+5'-UTR,intron-Distal4.2486035.89932K562NOLC1
chr171628441316284468+5'-UTR,intron-Distal,intron-Proximal4.03654400.00000K562DDX3X
chr171628445816284462+5'-UTR,intron-Distal5.69589400.00000K562NOLC1
chr171628448516284488+5'-UTR,intron-Distal8.54874400.00000HepG2SUB1
chr171628441516284496+5'-UTR,intron-Distal,intron-Proximal3.9773617.91963K562NCBP2
chr171628443416284458+5'-UTR,intron-Distal,intron-Proximal5.83677400.00000K562NOLC1
chr171628447016284480+5'-UTR,intron-Distal5.0633366.49390K562NOLC1
chr171628440916284429+5'-UTR,intron-Proximal5.0813828.19273K562NOLC1
chr171628442516284504+5'-UTR,intron-Distal,intron-Proximal3.8344441.60471K562DROSHA
chr171628449316284499+5'-UTR,intron-Distal,intron-Proximal7.81156144.79971HepG2SUB1
chr171628466016284721+5'-UTR,intron-Distal3.066544.07062HepG2CSTF2T
chr171628552616285569+CDS,intron-Distal,intron-Proximal3.7273118.21097K562YBX3
chr171628588116285886+CDS5.3909915.18855K562RPS3
chr171628555216285576+CDS,intron-Distal,intron-Proximal3.563319.04477K562RPS3
chr171628523616285280+CDS,intron-Distal3.497369.36347K562RPS3
chr171628546316285507+CDS,intron-Distal,intron-Proximal3.109766.12315HepG2GRWD1
chr171628588516285905+CDS3.203767.42808HepG2LARP4
chr171628552816285584+CDS,intron-Distal,intron-Proximal3.091215.04837HepG2ZNF800
chr171628548716285495+CDS,intron-Distal,intron-Proximal4.3896712.23631K562YBX3
chr171628536016285380+CDS,intron-Distal3.460219.85276HepG2GRWD1
chr171628536816285392+CDS,intron-Distal4.4602518.07016HepG2RPS3
chr171628534816285363+CDS,intron-Distal3.136729.24716K562SND1
chr171628567216285693+CDS,intron-Proximal4.1287539.77080K562RPS3
chr171628569316285735+CDS3.4021814.16861K562RPS3
chr171628557316285594+CDS,intron-Proximal3.560309.56024HepG2YBX3
chr171628559516285641+CDS,intron-Proximal3.287335.66692K562SND1
chr171628542016285444+CDS,intron-Distal4.1054738.49154K562RPS3
chr171628534516285395+CDS,intron-Distal4.3318453.91571K562RPS3
chr171628559416285634+CDS,intron-Proximal3.710788.84930HepG2YBX3
chr171628535316285391+CDS,intron-Distal3.540984.22136HepG2RBM15
chr171628534716285368+CDS,intron-Distal4.5838021.01142HepG2RPS3
chr171628557616285633+CDS,intron-Proximal3.6015734.57631K562YBX3
chr171628531516285345+CDS,intron-Distal3.0160414.47515K562RPS3
chr171628557716285633+CDS,intron-Proximal3.061358.40987K562METAP2
chr171628558016285623+CDS,intron-Proximal3.844324.39950HepG2SND1
chr171628503616285134+intron-Distal,intron-Proximal3.551786.85960K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for UBB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for UBB is not available on ENCORE database.

  • 114 RBPs can affect the levels of UBB.  








The Knockdown/knockout RNA-Seq assay for UBB is not available on ENCORE database.





114 RBPs can affect the gene expression of UBB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
UBBENSG00000170315.96980.158608505.70280-0.285202.786601.71080HepG2AATF
UBBENSG00000170315.914834.1191011145.348800.412403.977402.86210HepG2ABCF1
UBBENSG00000170315.98205.124409140.50830-0.155701.944201.41770HepG2ACO1
UBBENSG00000170315.910083.556508016.421600.330903.026101.98710HepG2ADAR
UBBENSG00000170315.916435.6392021819.37080-0.408803.351502.77400HepG2AKAP1
UBBENSG00000170315.910759.4474014623.65280-0.4427012.9244011.63510HepG2AUH
UBBENSG00000170315.920976.6227017152.607200.290302.485401.74780HepG2CIRBP
UBBENSG00000170315.912950.469609137.711100.5030023.3726021.86420HepG2CKAP4
UBBENSG00000170315.98014.697006164.325400.378604.022503.20770HepG2CPSF6
UBBENSG00000170315.96530.663408708.59610-0.415202.844701.46210HepG2CSTF2T
UBBENSG00000170315.910458.9251013023.40370-0.316403.837203.10220HepG2CELF1
UBBENSG00000170315.99795.055008453.288000.212404.089303.09830HepG2DDX19B
UBBENSG00000170315.911840.915109361.861400.338803.127802.06030HepG2DDX5
UBBENSG00000170315.911948.1395017952.85320-0.587406.282505.38130HepG2DDX6
UBBENSG00000170315.912586.321108744.779900.525306.643805.68120HepG2DKC1
UBBENSG00000170315.99193.342408072.238700.187502.274901.63240HepG2DNAJC21
UBBENSG00000170315.96645.033508641.76160-0.379002.621701.54750HepG2AGO1
UBBENSG00000170315.910173.7039017261.32820-0.762709.747008.67550HepG2EIF2S1
UBBENSG00000170315.914655.9642018571.69200-0.341602.005001.41350HepG2EIF4B
UBBENSG00000170315.910151.0611013233.43770-0.382603.376802.48230HepG2EIF4G2
UBBENSG00000170315.910751.453208931.190200.267502.768101.93330HepG2EWSR1
UBBENSG00000170315.97677.3142011253.78920-0.551705.942504.85650HepG2FIP1L1
UBBENSG00000170315.99047.7098011674.55710-0.367702.225201.51330HepG2FUBP3
UBBENSG00000170315.913771.6888019243.93320-0.482705.344904.40370HepG2FXR1
UBBENSG00000170315.914650.8559017853.73710-0.285201.958401.39460HepG2G3BP1
UBBENSG00000170315.97454.335308726.07710-0.227303.268902.21130HepG2HDGF
UBBENSG00000170315.910169.011908149.570600.319303.532702.81420HepG2HNRNPA1
UBBENSG00000170315.910221.7641012868.51260-0.332203.261302.25720HepG2HNRNPA2B1
UBBENSG00000170315.913020.380309064.822000.522308.417407.26090HepG2HNRNPC
UBBENSG00000170315.911701.6091010344.961200.177702.151901.51300HepG2HNRNPF
UBBENSG00000170315.912563.5592018073.46640-0.524606.283105.25990HepG2HNRNPK
UBBENSG00000170315.913379.8398010186.766500.393304.871903.93720HepG2IGF2BP1
UBBENSG00000170315.99487.2249017028.67060-0.843903.452802.35400HepG2IGF2BP3
UBBENSG00000170315.910869.888209198.214800.240806.649705.56280HepG2ILF2
UBBENSG00000170315.911820.5261018253.05380-0.626806.092104.54940HepG2KHSRP
UBBENSG00000170315.910895.5263019359.04670-0.8293010.761209.57600HepG2MATR3
UBBENSG00000170315.96273.497307647.19510-0.285702.911301.66410HepG2NAA15
UBBENSG00000170315.914801.9695019815.60560-0.420803.910303.16150HepG2NCBP2
UBBENSG00000170315.911351.9728013883.60870-0.290403.670702.79070HepG2NOL12
UBBENSG00000170315.911101.1246017649.59200-0.668907.584206.40390HepG2PABPC4
UBBENSG00000170315.97609.093908913.39110-0.228203.706102.74150HepG2PARN
UBBENSG00000170315.914537.6724019573.53170-0.4291013.4650012.28710HepG2PCBP1
UBBENSG00000170315.912319.161509567.856300.364508.685607.42070HepG2PRPF4
UBBENSG00000170315.98638.320706956.823100.312202.337301.59190HepG2PRPF8
UBBENSG00000170315.912590.2465019916.29100-0.6616028.4184027.02360HepG2PTBP1
UBBENSG00000170315.917331.8262014059.423500.301804.281403.45800HepG2PUM2
UBBENSG00000170315.915218.806009310.082000.7089038.8079037.02480HepG2PUS1
UBBENSG00000170315.912089.3132021570.92060-0.8354032.1702030.40900HepG2QKI
UBBENSG00000170315.97317.7204010162.29760-0.473809.084007.64960HepG2RBM15
UBBENSG00000170315.912461.2938019576.58670-0.6517014.8992013.39960HepG2RBM25
UBBENSG00000170315.99356.6118022165.34290-1.2442057.8459056.13050HepG2NELFE
UBBENSG00000170315.913029.7360020643.23680-0.6639032.0015030.33060HepG2RECQL
UBBENSG00000170315.914932.4894011145.062300.422005.010304.12700HepG2RPLP0
UBBENSG00000170315.97306.625409311.24550-0.349803.863602.92300HepG2RPS2
UBBENSG00000170315.914430.0546010277.821100.489403.330602.58860HepG2SF3A3
UBBENSG00000170315.98532.432706600.112900.370404.045203.20730HepG2SF3B1
UBBENSG00000170315.911294.8066020736.34310-0.8765053.6563051.70570HepG2SF3B4
UBBENSG00000170315.97953.596409351.92520-0.233706.046705.15370HepG2SMN1
UBBENSG00000170315.914099.2390015850.05680-0.168902.868002.36030HepG2SRFBP1
UBBENSG00000170315.913808.0524021643.87990-0.6484030.7805029.57810HepG2SRSF1
UBBENSG00000170315.913194.2124010163.814600.376402.794702.09590HepG2SRSF7
UBBENSG00000170315.97136.8441017608.12800-1.3029094.0100091.76410HepG2SRSF9
UBBENSG00000170315.917991.4500013761.586500.3866011.7032010.79120HepG2SSB
UBBENSG00000170315.96345.167108463.13710-0.415502.498601.35870HepG2SUB1
UBBENSG00000170315.910678.4504014882.78430-0.478907.305006.37550HepG2SUCLG1
UBBENSG00000170315.99600.676007597.820400.337503.801002.71110HepG2SUPT6H
UBBENSG00000170315.914218.7928019453.32860-0.4522011.3384010.32580HepG2TAF15
UBBENSG00000170315.94753.029606500.28010-0.451705.642904.66300HepG2TARDBP
UBBENSG00000170315.917546.041409567.388400.874805.144003.72670HepG2TBRG4
UBBENSG00000170315.99993.6623017876.05660-0.8389025.1344022.66180HepG2TIA1
UBBENSG00000170315.97212.613608750.19610-0.278802.666202.17370HepG2TIAL1
UBBENSG00000170315.97290.989708828.14050-0.276005.305704.57610HepG2TRIM56
UBBENSG00000170315.99669.7939013707.64010-0.503405.125703.96660HepG2UBE2L3
UBBENSG00000170315.94381.938105303.83550-0.275502.145301.47670HepG2UCHL5
UBBENSG00000170315.97786.647309114.87650-0.227204.230503.39670HepG2UPF1
UBBENSG00000170315.96095.534508907.86490-0.547304.280902.70390HepG2XRCC5
UBBENSG00000170315.912015.653608838.759100.442904.426403.51650HepG2XRN2
UBBENSG00000170315.910863.693609442.287000.202204.213303.41160HepG2ZC3H8
UBBENSG00000170315.920338.5776013655.054200.5747024.0824022.52270K562AGGF1
UBBENSG00000170315.920267.8300015004.893300.433705.955604.37700K562AKAP8
UBBENSG00000170315.921651.7282014208.715800.607607.902006.74440K562AKAP8L
UBBENSG00000170315.913604.9828017314.57150-0.347903.649402.99400K562AQR
UBBENSG00000170315.918040.7697014908.387900.275002.738401.82980K562ATP5C1
UBBENSG00000170315.98895.6120010901.36400-0.293306.584605.07290K562BCLAF1
UBBENSG00000170315.96914.879408542.66170-0.305002.716301.85080K562BOP1
UBBENSG00000170315.96385.558707936.91320-0.313802.799001.73720K562CCAR1
UBBENSG00000170315.97377.486609083.27650-0.300103.703302.79770K562CPSF6
UBBENSG00000170315.96959.021008270.30790-0.249103.258502.09840K562CSTF2
UBBENSG00000170315.910300.6590013974.49650-0.4401012.3936011.12130K562DDX47
UBBENSG00000170315.97062.092008885.07950-0.331302.910101.54390K562DHX30
UBBENSG00000170315.920454.6343015289.514400.419809.958608.08350K562DKC1
UBBENSG00000170315.96603.469708534.98280-0.370203.985202.34980K562DNAJC21
UBBENSG00000170315.915602.1746013863.614000.170301.983701.35670K562EIF2S2
UBBENSG00000170315.95472.984708073.32840-0.560803.449602.31650K562EIF3A
UBBENSG00000170315.99151.525107604.674400.267003.581302.23860K562EIF4B
UBBENSG00000170315.916462.6515020500.82940-0.316506.347904.94430K562EIF4G2
UBBENSG00000170315.98307.1536011963.92020-0.526304.401402.30650K562ESF1
UBBENSG00000170315.910750.298507371.136700.5443013.2966010.14360K562EWSR1
UBBENSG00000170315.910402.8203013113.35540-0.334104.207402.60460K562EXOSC5
UBBENSG00000170315.914774.0642011250.998200.392904.708903.58080K562FIP1L1
UBBENSG00000170315.97321.218709332.29030-0.350103.029001.83880K562FKBP4
UBBENSG00000170315.96388.729709242.06470-0.532707.547506.09650K562FMR1
UBBENSG00000170315.95583.761207833.50360-0.488405.430504.10250K562FTO
UBBENSG00000170315.910056.723507966.522700.336005.057102.46820K562FUBP3
UBBENSG00000170315.99925.952408781.869300.176602.197501.64660K562FXR1
UBBENSG00000170315.94093.643708430.98810-1.042306.155105.01050K562G3BP2
UBBENSG00000170315.97213.330309961.47360-0.465704.947003.02510K562GEMIN5
UBBENSG00000170315.96797.186108672.27450-0.351504.045003.08830K562GPKOW
UBBENSG00000170315.911303.1359014678.48240-0.377005.301103.82980K562HNRNPA1
UBBENSG00000170315.97622.8024010744.63960-0.495208.651807.64710K562HNRNPC
UBBENSG00000170315.914952.2066012628.780300.243502.421101.44090K562HNRNPL
UBBENSG00000170315.912265.9992016256.06140-0.406308.100106.57570K562HNRNPU
UBBENSG00000170315.918397.4606015253.069800.270302.497501.73800K562HSPD1
UBBENSG00000170315.96242.715208014.10670-0.360403.354601.71480K562KHDRBS1
UBBENSG00000170315.918772.1645015078.953100.316003.931802.92650K562KIF1C
UBBENSG00000170315.94820.929007405.09120-0.619206.079304.63320K562KRR1
UBBENSG00000170315.920255.1760014434.305600.488702.824701.73640K562MAK16
UBBENSG00000170315.97010.543008465.11580-0.272002.660401.80500K562METAP2
UBBENSG00000170315.99573.6106011453.47410-0.258705.449404.33770K562MTPAP
UBBENSG00000170315.918219.3676011840.242700.621706.267504.73810K562NAA15
UBBENSG00000170315.910168.8083014104.27670-0.472002.678601.46650K562PABPC1
UBBENSG00000170315.916497.4734012773.029000.369004.059403.04190K562PPIG
UBBENSG00000170315.912009.200009668.834300.312602.987602.20860K562PRPF8
UBBENSG00000170315.931208.5632014091.055501.147108.175007.29000K562PUS1
UBBENSG00000170315.922544.6300013729.686900.7154015.2975013.88720K562RBM15
UBBENSG00000170315.95654.161808247.71070-0.544705.916104.46090K562SF3B1
UBBENSG00000170315.96886.654408742.23580-0.344203.422502.00170K562SLBP
UBBENSG00000170315.99768.033007626.986000.356905.207402.80880K562SLTM
UBBENSG00000170315.911453.4035012865.00130-0.167703.214002.21280K562SRPK2
UBBENSG00000170315.911440.4409014761.08250-0.367703.848502.22530K562SSRP1
UBBENSG00000170315.97841.287509907.94710-0.337503.092602.01130K562UCHL5
UBBENSG00000170315.98018.9969010089.15950-0.331302.916801.66840K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for UBB is not available on ENCORE database.





7 RBPs can affect the splicing of UBB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUBBENSG00000170315.9chr17+162852151628529616284603162847761628540716285444-0.309000.000000.00000excludedK562SMNDC1
SEUBBENSG00000170315.9chr17+162852151628529616284603162847761628540716285500-0.133000.000100.06625excludedK562HLTF
SEUBBENSG00000170315.9chr17+1628521516285296162846031628477616285407162855000.134000.001000.03760includedK562HNRNPU
A3SSUBBENSG00000170315.9chr17+1628536016285444162854071628544416284408162844290.827000.000450.08318longerK562SUPV3L1
A5SSUBBENSG00000170315.9chr17+1628476516284993162847651628477616285215162852690.105000.000000.00000longerK562AQR
A5SSUBBENSG00000170315.9chr17+1628460316284820162846031628477616285215162860540.083000.000380.03847longerHepG2RBM22
A5SSUBBENSG00000170315.9chr17+1628460316284820162846031628477616285215162860540.084000.000010.00116longerHepG2HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for UBB is not avaliable on ENCORE database.