SMS

General Information

Gene Name       : SMS
Gene ID             : ENSG00000102172.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SMS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SMSENSG00000102172.15106.4193.65100.03ENCSR000AEF
HepG2SMSENSG00000102172.1554.2781.8268.05ENCSR985KAT
K562SMSENSG00000102172.15130.82130.04130.43ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SMS is not avaliable on ENCORE database.



Proteins bound to RNA
  • SMS RNA is bound by 20 proteins.  







eCLIP assay for SMS is not avaliable on ENCORE database.





20 proteins are bound to SMS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX2201274822012771+3'-UTR,intron-Distal3.7108210.45191K562NOLC1
chrX2201275722012836+3'-UTR,intron-Distal4.4315110.81737K562TIA1
chrX2201277122012798+3'-UTR,intron-Distal3.3417712.72294K562NOLC1
chrX2201275022012834+3'-UTR,intron-Distal4.287786.74349HepG2DDX55
chrX2201277022012788+3'-UTR,intron-Distal5.6291935.73745HepG2SUB1
chrX2201274922012770+3'-UTR,intron-Distal5.1285325.76607HepG2SUB1
chrX2201278822012830+3'-UTR,intron-Distal3.111738.23088K562PABPC4
chrX2201278822012820+3'-UTR,intron-Distal4.7453115.29070HepG2SUB1
chrX2201274722012825+3'-UTR,intron-Distal3.047943.10134K562APOBEC3C
chrX2195889421958936+5'-UTR5.053989.40283K562YBX3
chrX2199064121990677+5'-UTR,CDS,intron-Distal3.196137.93618K562UCHL5
chrX2198540721985433+5'-UTR,CDS3.891563.67607K562YBX3
chrX2195896021958992+5'-UTR,CDS,intron-Proximal3.825036.42513K562YBX3
chrX2199067721990690+CDS,intron-Distal,intron-Proximal3.591475.17903K562UCHL5
chrX2199699321997039+CDS,intron-Proximal6.1331618.21203K562LIN28B
chrX2199517721995275+CDS,intron-Proximal3.342596.39282HepG2GRWD1
chrX2199517721995190+CDS,intron-Proximal3.188887.86167K562YBX3
chrX2199520921995246+CDS3.222547.87605K562YBX3
chrX2199517921995232+CDS4.284463.90287K562LIN28B
chrX2199517721995294+CDS,intron-Proximal3.611609.28980HepG2BCLAF1
chrX2199620921996233+CDS,intron-Proximal5.1639610.32591K562LIN28B
chrX2195935021959466+CDS,intron-Distal3.000483.54092HepG2NKRF
chrX2199517621995259+CDS,intron-Proximal3.4778711.59993K562UCHL5
chrX2196542121965495+intron-Distal4.562305.79972HepG2RBFOX2
chrX2201208422012170+intron-Distal3.983296.90077HepG2PTBP1
chrX2201198722012084+intron-Distal3.140514.86294HepG2PTBP1
chrX2201296222013044+intron-Distal3.693253.11181HepG2CSTF2
chrX2201208722012150+intron-Distal6.4246019.77775HepG2PCBP2
chrX2197055221970594+intron-Distal3.961533.30687K562EXOSC5
chrX2201207622012158+intron-Distal4.185566.11515K562PTBP1
chrX2201296222013038+intron-Distal3.245363.99385K562CSTF2T
chrX2198491521985116+intron-Distal3.309074.52210K562KHSRP
chrX2196999221970059+intron-Distal3.299503.43829K562EXOSC5
chrX2201198022012076+intron-Distal3.469095.44125K562PTBP1
chrX2201210322012184+intron-Distal3.128813.06005HepG2QKI
chrX2201201322012087+intron-Distal4.8327311.86431HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SMS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SMS is not available on ENCORE database.

  • 122 RBPs can affect the levels of SMS.  








The Knockdown/knockout RNA-Seq assay for SMS is not available on ENCORE database.





122 RBPs can affect the gene expression of SMS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SMSENSG00000102172.11670.343301457.96750-1.1210011.549008.29360HepG2AARS
SMSENSG00000102172.111465.296202041.30320-0.478303.786402.69350HepG2ABCF1
SMSENSG00000102172.112013.897501627.126600.307604.711103.95810HepG2ACO1
SMSENSG00000102172.11791.211501617.88800-1.0320017.4004015.26480HepG2ADAR
SMSENSG00000102172.11964.733401292.61700-0.422102.662801.77920HepG2BCLAF1
SMSENSG00000102172.111239.923401946.52020-0.650608.884307.88670HepG2BOP1
SMSENSG00000102172.111388.162202786.24660-1.0051010.831008.94200HepG2CCAR1
SMSENSG00000102172.111291.513001626.73070-0.332905.213404.35220HepG2CKAP4
SMSENSG00000102172.111338.485801772.66020-0.405301.944801.30870HepG2CNOT7
SMSENSG00000102172.113557.167702435.001600.5467013.3074012.10440HepG2CELF1
SMSENSG00000102172.112273.573702617.99720-0.203502.641301.91370HepG2DAZAP1
SMSENSG00000102172.112641.082801462.490200.8526011.335109.90020HepG2DDX55
SMSENSG00000102172.111424.433002029.27360-0.510602.552401.61500HepG2DDX59
SMSENSG00000102172.111076.315701616.88400-0.587106.562005.06270HepG2DDX5
SMSENSG00000102172.11678.706701556.70830-1.1976038.8199037.06060HepG2DKC1
SMSENSG00000102172.111397.989901614.73920-0.207902.414901.79890HepG2DNAJC2
SMSENSG00000102172.111210.320701577.16790-0.381902.824301.89440HepG2EEF2
SMSENSG00000102172.11886.836301232.94870-0.475403.555802.35060HepG2EIF3G
SMSENSG00000102172.11834.818501950.76630-1.2245019.7684018.08400HepG2EIF4A3
SMSENSG00000102172.112668.202101899.432700.490203.311402.56270HepG2EIF4B
SMSENSG00000102172.112230.147302583.01080-0.211902.315201.53770HepG2EIF4G1
SMSENSG00000102172.111771.531202474.32390-0.482005.113504.02640HepG2EIF4G2
SMSENSG00000102172.111934.322102878.65560-0.5736013.8447012.66480HepG2ETF1
SMSENSG00000102172.112128.085201589.955800.420504.834603.73660HepG2EWSR1
SMSENSG00000102172.111664.288001244.339500.419403.767402.46320HepG2FASTKD2
SMSENSG00000102172.11729.731201139.98030-0.643606.191404.85190HepG2GEMIN5
SMSENSG00000102172.111076.693701422.34560-0.401702.815201.78610HepG2GNB2L1
SMSENSG00000102172.111358.861902025.67220-0.576005.533704.64990HepG2GPKOW
SMSENSG00000102172.111214.051101640.91490-0.434702.404801.36620HepG2GRSF1
SMSENSG00000102172.11816.060101644.74990-1.0111019.3099017.85780HepG2HNRNPA1
SMSENSG00000102172.111098.012501829.47440-0.7365011.026109.72070HepG2HNRNPC
SMSENSG00000102172.111280.357501882.60640-0.5562010.882709.58460HepG2HNRNPF
SMSENSG00000102172.111472.962001933.13910-0.392203.206102.53470HepG2HNRNPLL
SMSENSG00000102172.111302.236001817.37950-0.480908.958807.91620HepG2HNRNPU
SMSENSG00000102172.111099.571401853.84000-0.7536013.7468012.26100HepG2IGF2BP1
SMSENSG00000102172.111210.324401688.81350-0.480603.413702.06450HepG2KHDRBS1
SMSENSG00000102172.112269.148802940.76000-0.374002.353301.59160HepG2LARP4
SMSENSG00000102172.111181.048301969.06860-0.737408.975607.80770HepG2MAGOH
SMSENSG00000102172.111302.532701668.48870-0.357203.140502.28190HepG2MSI2
SMSENSG00000102172.111358.358001971.61970-0.537503.414802.32990HepG2MTPAP
SMSENSG00000102172.111200.020501714.12050-0.514405.325604.30370HepG2NSUN2
SMSENSG00000102172.112310.858501620.123500.512202.648201.78400HepG2PABPC1
SMSENSG00000102172.111236.019101751.14870-0.502609.135208.13630HepG2PCBP1
SMSENSG00000102172.111357.957101620.95830-0.255402.483001.78080HepG2PPIL4
SMSENSG00000102172.111540.588601781.93850-0.210001.995401.51730HepG2PTBP1
SMSENSG00000102172.111797.482002478.18440-0.463303.582602.91590HepG2PUF60
SMSENSG00000102172.111302.898301657.32780-0.347105.293604.49170HepG2PUS1
SMSENSG00000102172.113354.463901473.934701.186308.056806.89220HepG2RAVER1
SMSENSG00000102172.111063.282102027.87660-0.9314017.1212015.70780HepG2RPLP0
SMSENSG00000102172.11899.985701447.60470-0.685704.865403.62900HepG2RPS10
SMSENSG00000102172.11747.411201245.80170-0.7371010.615509.50700HepG2RPS19
SMSENSG00000102172.111159.156101549.67420-0.418903.529402.62770HepG2RPS2
SMSENSG00000102172.11942.729001779.74900-0.916809.639308.17390HepG2RPS3A
SMSENSG00000102172.112055.604601581.875100.377803.221002.05590HepG2RPS5
SMSENSG00000102172.11654.932301116.27750-0.769307.030505.84380HepG2RRP9
SMSENSG00000102172.111488.151701913.40760-0.362603.176002.42200HepG2SF3B1
SMSENSG00000102172.111934.710302376.34380-0.296604.814003.92900HepG2SLBP
SMSENSG00000102172.11657.544801433.69270-1.1246013.6882010.44040HepG2SND1
SMSENSG00000102172.114051.425202717.493700.5761018.7391017.74050HepG2SRFBP1
SMSENSG00000102172.11779.114601393.02820-0.838309.266906.62780HepG2SRP68
SMSENSG00000102172.111926.896102446.93440-0.344705.262704.44190HepG2SRSF5
SMSENSG00000102172.111101.873901849.56350-0.7472018.8367017.31470HepG2SRSF7
SMSENSG00000102172.112136.778801575.386900.439608.949508.05700HepG2SRSF9
SMSENSG00000102172.111293.967102359.40520-0.8666030.2269028.94470HepG2SSB
SMSENSG00000102172.112386.426802782.76300-0.221703.025902.38070HepG2SUCLG1
SMSENSG00000102172.111667.789901392.066800.260602.265701.41050HepG2SUPT6H
SMSENSG00000102172.111292.996601740.64210-0.428906.007405.23380HepG2TAF15
SMSENSG00000102172.111373.086801884.29590-0.456604.540103.64110HepG2TARDBP
SMSENSG00000102172.11962.391801596.75540-0.730403.440502.25560HepG2TBRG4
SMSENSG00000102172.11579.337301765.94540-1.6080055.5231053.82200HepG2TIAL1
SMSENSG00000102172.111926.367502421.20150-0.329803.195602.25020HepG2TUFM
SMSENSG00000102172.112206.736301763.417400.323402.616502.00480HepG2U2AF1
SMSENSG00000102172.11508.43740860.12560-0.758507.421706.17100HepG2UCHL5
SMSENSG00000102172.111066.194601412.49050-0.405805.896805.07740HepG2UTP3
SMSENSG00000102172.11314.138501429.08590-2.18560112.93390110.11280HepG2ZC3H8
SMSENSG00000102172.112036.960301609.045200.340106.454805.71060HepG2ZNF622
SMSENSG00000102172.115061.834903625.702000.4813013.5790012.42380K562AGGF1
SMSENSG00000102172.114886.840503984.201300.294502.863101.85990K562AKAP8
SMSENSG00000102172.115642.769803772.732600.580709.467708.17510K562AKAP8L
SMSENSG00000102172.112629.738805859.59560-1.1559030.2919028.55010K562AQR
SMSENSG00000102172.114926.167803958.552500.315404.828003.58580K562ATP5C1
SMSENSG00000102172.112740.800403305.29520-0.270204.257103.04880K562BCLAF1
SMSENSG00000102172.112549.693003632.24860-0.510502.324601.53130K562BOP1
SMSENSG00000102172.113004.016404136.68450-0.461604.352402.50570K562BUD13
SMSENSG00000102172.111300.355201713.45650-0.398003.403502.20850K562CCAR1
SMSENSG00000102172.113484.764906554.31740-0.911407.421005.63470K562CNOT7
SMSENSG00000102172.112511.204103862.38220-0.621103.167302.32710K562CPSF6
SMSENSG00000102172.112046.333802507.55890-0.293203.455902.25430K562CSTF2
SMSENSG00000102172.114655.685605755.86710-0.306005.679504.79640K562DDX47
SMSENSG00000102172.115640.594804059.571800.4744010.870008.89730K562DKC1
SMSENSG00000102172.112162.407202888.39790-0.417602.651301.40100K562EEF2
SMSENSG00000102172.111747.406702791.05190-0.675607.038805.52940K562EFTUD2
SMSENSG00000102172.113211.945704486.19670-0.482008.848107.67320K562EIF2S2
SMSENSG00000102172.111118.298301742.92860-0.640203.894002.67810K562EIF3A
SMSENSG00000102172.112488.999902912.86310-0.226902.555401.78970K562EIF3G
SMSENSG00000102172.111741.915002605.15720-0.580708.161106.75370K562EIF4A3
SMSENSG00000102172.115773.206907061.81760-0.290704.643803.43990K562EIF4G2
SMSENSG00000102172.112137.569302590.09810-0.277002.527901.32110K562EXOSC5
SMSENSG00000102172.112293.236203062.11540-0.417103.622502.30730K562FKBP4
SMSENSG00000102172.112602.868503929.37940-0.594203.192902.26880K562FMR1
SMSENSG00000102172.112428.836703330.28510-0.455402.296201.46770K562FTO
SMSENSG00000102172.113150.693602709.243600.217702.428901.85480K562FXR1
SMSENSG00000102172.113049.660004075.88450-0.418507.265805.47310K562GLRX3
SMSENSG00000102172.112157.346103687.83230-0.773504.502703.49350K562GPKOW
SMSENSG00000102172.114559.503705978.70210-0.391003.490502.64410K562GRSF1
SMSENSG00000102172.113304.826103934.62620-0.251702.425101.42260K562HNRNPA1
SMSENSG00000102172.111467.050703528.16820-1.2660039.8227037.64300K562HNRNPC
SMSENSG00000102172.112348.424703150.38090-0.423805.075503.46600K562HNRNPF
SMSENSG00000102172.114406.341003511.147000.327502.213301.38430K562HNRNPM
SMSENSG00000102172.113392.325804357.16870-0.361105.660704.37150K562HNRNPU
SMSENSG00000102172.115502.642404003.723500.458707.009905.55300K562KIF1C
SMSENSG00000102172.112234.355303148.40410-0.494802.448401.57620K562KRR1
SMSENSG00000102172.114660.745303832.620500.282102.516801.50640K562MAK16
SMSENSG00000102172.115693.583304485.194000.344104.175803.02260K562MBNL1
SMSENSG00000102172.112535.671003599.64810-0.505502.498801.67050K562METAP2
SMSENSG00000102172.115900.759707527.12900-0.351203.621302.32870K562MSI2
SMSENSG00000102172.112701.888904285.27240-0.6654023.9960021.95590K562MTPAP
SMSENSG00000102172.114841.692403143.804000.622905.952004.47920K562NAA15
SMSENSG00000102172.113216.457004761.25830-0.5659027.7736025.80970K562NSUN2
SMSENSG00000102172.114103.805106296.76040-0.617604.294402.73250K562PABPC1
SMSENSG00000102172.112439.585503294.59820-0.433503.895802.90910K562PCBP3
SMSENSG00000102172.115652.643707256.25740-0.360305.576403.63840K562PNPT1
SMSENSG00000102172.111893.483202527.10760-0.416405.344604.23340K562POLR2G
SMSENSG00000102172.112202.686903163.29510-0.522206.646905.14370K562PSIP1
SMSENSG00000102172.116600.322507704.92270-0.223202.236201.50360K562PUF60
SMSENSG00000102172.116309.114808029.84820-0.347906.636505.13600K562PUM2
SMSENSG00000102172.116999.169703741.334800.9035018.9739017.58460K562PUS1
SMSENSG00000102172.114616.104003645.516900.340505.318304.52020K562RBM15
SMSENSG00000102172.111822.774603518.59360-0.9489020.0244017.53820K562RBM22
SMSENSG00000102172.111890.215702766.91180-0.549704.414903.37930K562RPS19
SMSENSG00000102172.114080.985205969.78340-0.548803.144601.50860K562SBDS
SMSENSG00000102172.113600.751204698.24240-0.383807.232105.96190K562SF3A3
SMSENSG00000102172.113174.918405194.29300-0.710203.191401.75500K562SFPQ
SMSENSG00000102172.111870.302902735.62830-0.548604.000602.69570K562SRFBP1
SMSENSG00000102172.111914.864802711.64240-0.501905.017602.75660K562SRP68
SMSENSG00000102172.114195.485004813.45940-0.198203.322502.30780K562SRPK2
SMSENSG00000102172.112915.701103596.69740-0.302803.208002.45120K562SRSF1
SMSENSG00000102172.111589.522601966.11980-0.306802.353301.39390K562SRSF4
SMSENSG00000102172.111690.413802630.31680-0.637904.269502.98320K562SUPV3L1
SMSENSG00000102172.112970.646002534.701600.228902.082201.36930K562SYNCRIP
SMSENSG00000102172.112334.386803640.31490-0.641008.905007.54170K562TARDBP
SMSENSG00000102172.112957.142703511.43630-0.247902.355401.60760K562TIA1
SMSENSG00000102172.111586.068903042.60600-0.9399015.6573013.29960K562TIAL1
SMSENSG00000102172.112327.445503231.95980-0.473705.844604.35400K562TRIM56
SMSENSG00000102172.111449.808802783.54640-0.9411010.504208.47460K562UCHL5
SMSENSG00000102172.112982.839105048.46820-0.7592032.2239030.09030K562UPF1
SMSENSG00000102172.113183.893604319.80650-0.440206.161404.82400K562WDR3
SMSENSG00000102172.115721.233006942.14820-0.279102.916601.58870K562WRN
SMSENSG00000102172.112212.812002833.92350-0.356902.725001.52980K562XRN2
SMSENSG00000102172.114731.643206601.22240-0.480406.695805.26050K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SMS is not available on ENCORE database.





16 RBPs can affect the splicing of SMS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.157000.000000.00000excludedK562SF3B4
SESMSENSG00000102172.11chrX+2198510021985163219586902195899121985313219854340.066000.000000.00000includedHepG2U2AF1
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.061000.000060.00346excludedK562AKAP8L
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.101000.000140.00267excludedHepG2U2AF2
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.054000.000200.00309excludedK562AQR
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.110000.000000.00000excludedK562PUS1
SESMSENSG00000102172.11chrX+2198510021985163219586902195899121985313219854340.069000.000140.00448includedK562U2AF1
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.140000.000050.00275excludedHepG2SF3A3
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.085000.000220.01384excludedHepG2SF3B4
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.100000.000000.00001excludedK562UTP18
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.085000.001010.02005excludedK562U2AF2
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.082000.000000.00014excludedK562RBM15
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.080000.000000.00014excludedK562AGGF1
SESMSENSG00000102172.11chrX+219906242199068921985313219854342199517821995354-0.082000.001240.04809excludedK562SF3B1
MXESMSENSG00000102172.11chrX+21985313219854342199001421990108219586902195899121990624219906890.077000.000980.017971includedK562DROSHA
MXESMSENSG00000102172.11chrX+21985313219854342199001421990108219586902195899121990624219906890.167000.000000.000021includedK562XRN2
MXESMSENSG00000102172.11chrX+21985313219854342199001421990108219586902195899121990624219906890.090000.001450.050421includedK562LIN28B
MXESMSENSG00000102172.11chrX+21985313219854342199001421990108219586902195899121990624219906890.088000.007190.048481includedK562AQR
MXESMSENSG00000102172.11chrX+21985313219854342199062421990689219586902195899121995178219953540.163000.000010.000881includedHepG2DDX55
MXESMSENSG00000102172.11chrX+21985313219854342199001421990108219586902195899121990624219906890.115000.000250.007881includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SMS is not avaliable on ENCORE database.