RYBP

General Information

Gene Name : RYBP
Gene ID : ENSG00000163602.10
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: RYBP)

Not Available

Antibody Validation

Thermo Fisher: PA5-19943

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	RYBP	ENSG00000163602.10	5.85	5.96	5.90	ENCSR000AEF
HepG2	RYBP	ENSG00000163602.10	5.45	9.40	7.43	ENCSR985KAT
K562	RYBP	ENSG00000163602.10	10.64	11.14	10.89	ENCSR000AEO

Assays

4 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
eCLIP	eCLIP: 4140	ENCSR179MPN	RYBP	K562	Released	ENCAB686SDS	ENCSR407QDZ
knockdown followed by RNA-seq	RYBP-BGKcLV19-K562	ENCSR607RGV	RYBP	K562	Released		ENCSR978MMZ	CRISPR	KD% = 55.2,60.8
knockdown followed by RNA-seq	RYBP-BGHcLV20-HepG2	ENCSR439TMT	RYBP	HepG2	Released		ENCSR306EWE	CRISPR	KD% = 87.0,86.9
knockdown followed by RNA-seq	RYBP-BGRSLV06-RS293		RYBP	Ribo-STAMP-293T	Released			shRNA	KD% = ,

eCLIP

RBP	Exp_UID	Cell_Line	ENCODE_ACCESSION	Control_ENCODE_ACCESSION	ENCODE_Antibody_ID	Antibody	Lot_num	Status	Project
RYBP	4140	K562	ENCSR179MPN	ENCSR407QDZ	ENCAB686SDS	PA5-19943	UCF2796583	Released	ENCODE4

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
RYBP	ENCAB686SDS	PA5-19943	UCF2796583				BGHcLV20-31, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
RYBP	K562	CRISPR	ENCSR607RGV	ENCSR978MMZ	RYBP-BGKcLV19-43,RYBP-BGKcLV19-44	NT-BGKcLV19-1,NT-BGKcLV19-2	55.2,60.8	Released	ENCODE4
RYBP	HepG2	CRISPR	ENCSR439TMT	ENCSR306EWE	RYBP-BGHcLV20-31,RYBP-BGHcLV20-32	NT-BGHcLV20-1,NT-BGHcLV20-2	87.0,86.9	Released	ENCODE4
RYBP	HepG2	CRISPR			BGHcLV20-33,BGHcLV20-34	BGHcLV20-1,BGHcLV20-2	84.2,81.9	NotSatisfied	ENCODE4
RYBP	Ribo-STAMP-293T	shRNA			RYBP-BGRSLV06-35,RYBP-BGRSLV06-36	NT-BGRSLV06-1,NT-BGRSLV06-2	,	Released	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
RYBP	Product_ID: PA5-19943 Lot_ID: UCF2796583 Source: Thermo Fisher Target Name: RYBP-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for RYBP is not avaliable on ENCORE database.

Proteins bound to RNA

RYBP RNA is bound by 28 proteins.

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eCLIP assay for RYBP is not avaliable on ENCORE database.

28 proteins are bound to RYBP RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr3	72495025	72495093	-	intron-Distal	6.45012	64.08058	K562	EXOSC5
chr3	72493189	72493245	-	intron-Distal	5.15974	25.80087	K562	EXOSC5
chr3	72494991	72495025	-	intron-Distal	6.56476	25.04720	K562	EXOSC5
chr3	72495327	72495417	-	intron-Distal	5.60653	23.04165	K562	EXOSC5
chr3	72494724	72494778	-	intron-Distal	5.58975	23.04165	K562	EXOSC5
chr3	72493345	72493411	-	intron-Distal	5.38000	20.72804	K562	EXOSC5
chr3	72483367	72483432	-	intron-Distal	6.26410	20.44285	HepG2	QKI
chr3	72495456	72495523	-	intron-Distal	4.06090	19.14480	K562	EXOSC5
chr3	72493440	72493497	-	intron-Distal	4.80512	17.34220	K562	EXOSC5
chr3	72494781	72494819	-	intron-Distal	6.02873	16.65497	K562	EXOSC5
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 102 entries

eCLIP assay for RYBP is not avaliable on ENCORE database.

Summary
DE Affected by

Diffrential Expression

The Knockdown/knockout assay for RYBP is not available on ENCORE database.
125 RBPs can affect the levels of RYBP.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for RYBP is not available on ENCORE database.

125 RBPs can affect the gene expression of RYBP :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RYBP	ENSG00000163602.9	690.48710	1921.11460	-1.47630	72.98010	70.63640	HepG2	SUCLG1
RYBP	ENSG00000163602.9	1032.63560	2678.19310	-1.37490	70.63190	68.98250	HepG2	SRSF1
RYBP	ENSG00000163602.9	969.23120	2565.81520	-1.40450	67.28120	65.10940	HepG2	SF3B4
RYBP	ENSG00000163602.9	720.02220	1578.29780	-1.13230	45.60710	43.58160	HepG2	SMN1
RYBP	ENSG00000163602.9	1279.18580	2742.75680	-1.10040	44.42750	42.85090	HepG2	NELFE
RYBP	ENSG00000163602.9	1120.60800	2464.54270	-1.13700	43.75250	42.12990	HepG2	PTBP1
RYBP	ENSG00000163602.9	532.55800	1476.77380	-1.47140	43.62900	42.08560	HepG2	TIAL1
RYBP	ENSG00000163602.9	816.20070	2628.28010	-1.68710	37.67950	35.54970	HepG2	MATR3
RYBP	ENSG00000163602.9	944.78540	2962.11010	-1.64860	35.47870	33.85680	HepG2	AKAP1
RYBP	ENSG00000163602.9	1321.39430	2554.58250	-0.95100	34.36810	32.65750	HepG2	RECQL
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 150 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

RYBP

General Information

Functions

Localization

Domains (AlphaFold: RYBP)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for RYBP is not avaliable on ENCORE database.

28 proteins are bound to RYBP RNA:

eCLIP assay for RYBP is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for RYBP is not available on ENCORE database.

125 RBPs can affect the gene expression of RYBP :

The Knockdown/knockout RNA-Seq assay for RYBP is not available on ENCORE database.

No RBPs affect the alternative splcing events of RYBP on ENCORE database.

The Knockdown/knockout RNA-Seq assay for RYBP is not avaliable on ENCORE database.