ESPL1

General Information

Gene Name       : ESPL1
Gene ID             : ENSG00000135476.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ESPL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ESPL1ENSG00000135476.1112.0019.4415.72ENCSR000AEF
HepG2ESPL1ENSG00000135476.1116.3011.1813.74ENCSR985KAT
K562ESPL1ENSG00000135476.1120.9419.8120.38ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ESPL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ESPL1 RNA is bound by 9 proteins.  







eCLIP assay for ESPL1 is not avaliable on ENCORE database.





9 proteins are bound to ESPL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr125368419853684264+3'-UTR,CDS,intron-Proximal4.009894.68902HepG2PPIG
chr125367784153677886+3'-UTR,CDS,intron-Proximal3.334643.34848HepG2PPIG
chr125367781553677901+3'-UTR,CDS,intron-Proximal3.673645.29272K562BUD13
chr125368180553681907+3'-UTR,CDS4.386816.64430HepG2PPIG
chr125367731853677371+3'-UTR,CDS,intron-Proximal4.027314.98250K562AQR
chr125366282253662923+5'-UTR,CDS3.849043.66655K562YBX3
chr125366208953662187+5'-UTR,intron-Proximal3.345244.09778HepG2NCBP2
chr125366275853662829+5'-UTR,CDS,intron-Proximal5.249154.90235K562SF3B4
chr125366216153662242+5'-UTR,intron-Proximal4.842334.48002K562AQR
chr125366867153668719+5'-UTR,CDS3.836145.79938K562LIN28B
chr125366303453663134+5'-UTR,CDS5.495529.68097K562RBM15
chr125366317053663267+5'-UTR,CDS4.5692410.40953K562RBM15
chr125366328753663337+5'-UTR,CDS4.850365.17013K562RBM15
chr125366339053663427+5'-UTR,CDS4.345133.81597K562RBM15
chr125367052953670590+5'-UTR,CDS4.377166.36347HepG2PPIG
chr125366345453663515+5'-UTR,CDS4.843637.33752K562RBM15
chr125367795153677997+intron-Proximal4.734824.09264K562AQR
chr125367795153678014+intron-Proximal4.245663.49003K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ESPL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ESPL1 is not available on ENCORE database.

  • 140 RBPs can affect the levels of ESPL1.  








The Knockdown/knockout RNA-Seq assay for ESPL1 is not available on ENCORE database.





140 RBPs can affect the gene expression of ESPL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ESPL1ENSG00000135476.7270.07910507.29860-0.909508.806307.02220HepG2AATF
ESPL1ENSG00000135476.7467.55950832.78940-0.8328015.8059014.60580HepG2ACO1
ESPL1ENSG00000135476.7830.06610545.513700.605505.470604.13350HepG2ADAR
ESPL1ENSG00000135476.7191.14260434.01370-1.183109.434608.51650HepG2AKAP1
ESPL1ENSG00000135476.7114.18770236.94240-1.053106.658005.08530HepG2AKAP8
ESPL1ENSG00000135476.7625.03550836.77670-0.420904.552903.58640HepG2AKAP8L
ESPL1ENSG00000135476.765.56450359.10640-2.4534029.7110027.56210HepG2ASCC1
ESPL1ENSG00000135476.7529.83890795.33510-0.586005.512103.60580HepG2ATP5C1
ESPL1ENSG00000135476.7462.417201114.69920-1.2694034.1543032.21950HepG2AUH
ESPL1ENSG00000135476.7471.64020666.57460-0.499102.339601.48030HepG2BCCIP
ESPL1ENSG00000135476.7279.91600579.08160-1.048806.004504.73850HepG2BCLAF1
ESPL1ENSG00000135476.724.18570502.89640-4.3780026.4398024.90380HepG2BOP1
ESPL1ENSG00000135476.7500.61180660.39550-0.399602.946801.67750HepG2BUD13
ESPL1ENSG00000135476.7183.21620606.25740-1.7264029.6166027.64210HepG2CALR
ESPL1ENSG00000135476.7618.05360341.176900.857107.966606.70530HepG2CIRBP
ESPL1ENSG00000135476.7221.65010832.69810-1.9095063.0368060.85590HepG2CKAP4
ESPL1ENSG00000135476.772.28000245.07910-1.761602.338401.63840HepG2CNOT7
ESPL1ENSG00000135476.7119.95140461.65910-1.9444010.468009.21550HepG2CPSF6
ESPL1ENSG00000135476.7323.34110519.39310-0.683804.153502.36840HepG2CSTF2T
ESPL1ENSG00000135476.7433.41430902.99620-1.0590021.2485019.80320HepG2CELF1
ESPL1ENSG00000135476.7551.99190970.91590-0.8147010.763209.45220HepG2DAZAP1
ESPL1ENSG00000135476.7378.57370559.75490-0.564204.329803.50150HepG2DDX21
ESPL1ENSG00000135476.7283.48160547.72120-0.9502010.868309.10410HepG2DDX24
ESPL1ENSG00000135476.7229.09260415.74480-0.859806.146305.24910HepG2DDX3X
ESPL1ENSG00000135476.7292.15910655.44350-1.165706.201705.09860HepG2DDX55
ESPL1ENSG00000135476.7172.47570524.25680-1.603907.327505.77640HepG2DDX59
ESPL1ENSG00000135476.7444.19430681.73060-0.618005.193403.84310HepG2DDX5
ESPL1ENSG00000135476.795.02600357.15100-1.9101018.8087017.39110HepG2DDX6
ESPL1ENSG00000135476.7539.14810796.77700-0.563506.583705.62310HepG2DKC1
ESPL1ENSG00000135476.7394.58840549.27330-0.477203.068802.33270HepG2DNAJC21
ESPL1ENSG00000135476.7438.06960544.49750-0.313801.888401.33130HepG2DNAJC2
ESPL1ENSG00000135476.7317.01140484.30080-0.611404.292402.90770HepG2EFTUD2
ESPL1ENSG00000135476.7181.64060515.41680-1.5047016.3134013.88440HepG2AGO1
ESPL1ENSG00000135476.788.15810343.32040-1.9614020.2541018.74840HepG2EIF2S1
ESPL1ENSG00000135476.7209.16440471.62140-1.1730011.588509.87850HepG2EIF3D
ESPL1ENSG00000135476.7463.46850957.89120-1.0474022.1244020.24370HepG2EIF4G1
ESPL1ENSG00000135476.7616.58230917.59430-0.573605.169604.07660HepG2EIF4G2
ESPL1ENSG00000135476.7378.676201279.81430-1.7569064.1990062.03100HepG2ETF1
ESPL1ENSG00000135476.7457.04340813.86370-0.8325010.969309.33510HepG2EWSR1
ESPL1ENSG00000135476.7272.37590533.40440-0.9696010.950708.93050HepG2FASTKD2
ESPL1ENSG00000135476.7376.58870545.48320-0.534502.568301.34150HepG2FKBP4
ESPL1ENSG00000135476.7254.68540462.50690-0.860803.163202.07480HepG2FTO
ESPL1ENSG00000135476.71071.51720382.825301.4848025.5445023.69390HepG2FXR1
ESPL1ENSG00000135476.7542.90000377.015700.526003.275602.30150HepG2G3BP2
ESPL1ENSG00000135476.7502.90910795.12990-0.660907.337605.84300HepG2HDGF
ESPL1ENSG00000135476.7288.22690559.24410-0.956304.633502.80020HepG2HLTF
ESPL1ENSG00000135476.7347.90030554.53630-0.672605.281604.42900HepG2HNRNPA1
ESPL1ENSG00000135476.7546.80320892.31240-0.706507.654306.23720HepG2HNRNPA2B1
ESPL1ENSG00000135476.7280.68940616.84390-1.1359013.5599012.13470HepG2HNRNPC
ESPL1ENSG00000135476.7375.36040570.38440-0.603706.750205.69630HepG2HNRNPF
ESPL1ENSG00000135476.7530.34900359.615600.560403.706502.90660HepG2HNRNPK
ESPL1ENSG00000135476.7633.65630884.42200-0.481006.363205.38110HepG2HNRNPL
ESPL1ENSG00000135476.7280.25580499.35590-0.833303.743603.02110HepG2HNRNPLL
ESPL1ENSG00000135476.796.58950360.95990-1.9019020.9012019.24100HepG2IGF2BP2
ESPL1ENSG00000135476.7476.36530625.91370-0.393902.991402.23160HepG2ILF2
ESPL1ENSG00000135476.7451.10720234.022600.946703.162001.87150HepG2KHDRBS1
ESPL1ENSG00000135476.7406.31490623.33930-0.617405.176702.99200HepG2CCAR2
ESPL1ENSG00000135476.7498.26350968.58280-0.959009.282507.75320HepG2LARP4
ESPL1ENSG00000135476.7576.56190382.959000.590203.377902.65240HepG2MAGOH
ESPL1ENSG00000135476.7511.55230385.098200.409601.927601.39640HepG2MATR3
ESPL1ENSG00000135476.7261.01140493.56300-0.919105.373203.94670HepG2METAP2
ESPL1ENSG00000135476.7530.98860720.30570-0.439903.561302.64560HepG2MSI2
ESPL1ENSG00000135476.7338.48260604.88060-0.837609.288107.12070HepG2NAA15
ESPL1ENSG00000135476.7588.05470394.166100.577003.685602.95870HepG2NCBP2
ESPL1ENSG00000135476.7229.21990442.82850-0.950004.182703.26810HepG2NSUN2
ESPL1ENSG00000135476.7443.59550606.50030-0.451304.055803.05320HepG2PARN
ESPL1ENSG00000135476.7283.51230551.50280-0.960005.019803.65470HepG2PCBP2
ESPL1ENSG00000135476.7428.43600661.97290-0.627704.124902.08090HepG2PHF6
ESPL1ENSG00000135476.7551.77540390.027200.500403.904102.43460HepG2PKM
ESPL1ENSG00000135476.7320.65970617.89270-0.9463014.3908012.84360HepG2PRPF4
ESPL1ENSG00000135476.7208.22990505.28710-1.278908.023106.73150HepG2PRPF8
ESPL1ENSG00000135476.7704.95450919.04570-0.382602.897302.28910HepG2PUF60
ESPL1ENSG00000135476.7690.20770975.61620-0.499307.499606.62160HepG2PUM1
ESPL1ENSG00000135476.7708.30530848.26310-0.260102.278701.70670HepG2PUS1
ESPL1ENSG00000135476.7151.63650532.02180-1.8109013.9792012.50270HepG2RAVER1
ESPL1ENSG00000135476.7621.02170909.46620-0.550406.242505.02020HepG2RBM15
ESPL1ENSG00000135476.7107.848201069.68990-3.31010123.90950121.52590HepG2RBM22
ESPL1ENSG00000135476.7242.66390379.88900-0.646604.395103.56130HepG2RBM25
ESPL1ENSG00000135476.7479.01700832.06670-0.796608.274706.55510HepG2RBM27
ESPL1ENSG00000135476.7542.29330236.865601.194903.113801.48550HepG2RBM47
ESPL1ENSG00000135476.7600.40570430.133200.481104.122003.48470HepG2NELFE
ESPL1ENSG00000135476.7763.32990400.625200.9300015.4626014.19740HepG2RECQL
ESPL1ENSG00000135476.780.09740614.49880-2.9396062.3261060.15030HepG2RPLP0
ESPL1ENSG00000135476.7197.52280522.95660-1.404709.206407.58240HepG2RPS10
ESPL1ENSG00000135476.7115.07820458.95350-1.9957031.4334029.74480HepG2RPS19
ESPL1ENSG00000135476.7362.90550767.36850-1.0803013.9896012.28800HepG2RPS2
ESPL1ENSG00000135476.7581.32670783.33560-0.430303.127501.98010HepG2RPS5
ESPL1ENSG00000135476.747.33200499.80070-3.4005026.7800024.83360HepG2RRP9
ESPL1ENSG00000135476.7306.88130460.56000-0.585703.868602.75500HepG2SERBP1
ESPL1ENSG00000135476.7315.00180691.50450-1.1344011.204709.78670HepG2SF3A3
ESPL1ENSG00000135476.7188.77460494.22080-1.388506.594305.54350HepG2SF3B1
ESPL1ENSG00000135476.7302.40440402.38270-0.412102.505701.93900HepG2SF3B4
ESPL1ENSG00000135476.7624.94700881.23930-0.495806.650505.63780HepG2SLBP
ESPL1ENSG00000135476.7393.09750636.32900-0.694909.734108.64420HepG2SMN1
ESPL1ENSG00000135476.7360.26420543.48660-0.593202.615401.68660HepG2SMNDC1
ESPL1ENSG00000135476.7138.62070549.92270-1.9881011.007309.46300HepG2SNRNP70
ESPL1ENSG00000135476.7206.268401208.17890-2.55020116.24530114.21310HepG2SRFBP1
ESPL1ENSG00000135476.7227.60840531.90540-1.224605.594504.13010HepG2SRSF3
ESPL1ENSG00000135476.7509.20330907.43410-0.8336014.7433013.46070HepG2SRSF5
ESPL1ENSG00000135476.7180.27940560.39650-1.6362032.7022030.83530HepG2SRSF7
ESPL1ENSG00000135476.7149.10120341.70450-1.1965013.5306012.47480HepG2SRSF9
ESPL1ENSG00000135476.7363.31310594.44510-0.710305.474403.79710HepG2STAU1
ESPL1ENSG00000135476.7281.53470497.23920-0.820604.574103.01570HepG2SUB1
ESPL1ENSG00000135476.7123.51720260.23180-1.075106.193604.21980HepG2SUGP2
ESPL1ENSG00000135476.7369.20740600.96520-0.702907.139505.67880HepG2SUPT6H
ESPL1ENSG00000135476.7128.64910652.38690-2.3423014.9407013.58610HepG2SUPV3L1
ESPL1ENSG00000135476.7267.19340486.91470-0.865802.885502.14670HepG2TARDBP
ESPL1ENSG00000135476.7516.79210252.479701.033305.073303.66260HepG2TBRG4
ESPL1ENSG00000135476.794.56220437.21290-2.2090014.3562012.45260HepG2TFIP11
ESPL1ENSG00000135476.7270.21850595.32180-1.1395016.6832015.64240HepG2TIAL1
ESPL1ENSG00000135476.7305.14130600.74310-0.9773010.519209.52500HepG2TRIM56
ESPL1ENSG00000135476.7494.37220761.41090-0.623105.305704.45130HepG2U2AF1
ESPL1ENSG00000135476.7141.58750385.31870-1.444408.918407.55180HepG2UCHL5
ESPL1ENSG00000135476.7177.31440613.25820-1.7902040.9586038.94430HepG2UPF1
ESPL1ENSG00000135476.7311.89350630.34810-1.0151015.9425013.74190HepG2UTP18
ESPL1ENSG00000135476.7336.89520592.07760-0.8135010.326809.28680HepG2UTP3
ESPL1ENSG00000135476.7419.51290585.26930-0.480402.321401.35240HepG2XRCC6
ESPL1ENSG00000135476.7473.40300609.77920-0.365203.138102.43050HepG2ZC3H8
ESPL1ENSG00000135476.7268.06430674.46740-1.3312030.8680029.54720HepG2ZNF622
ESPL1ENSG00000135476.71935.172801682.765700.201501.980801.48490K562AGGF1
ESPL1ENSG00000135476.71065.959601326.52580-0.315503.426601.72230K562AKAP1
ESPL1ENSG00000135476.71766.738902455.06260-0.474705.107404.35260K562AQR
ESPL1ENSG00000135476.7779.840901062.74270-0.446503.464602.48930K562BOP1
ESPL1ENSG00000135476.73415.418504233.27500-0.309703.958302.78160K562CELF1
ESPL1ENSG00000135476.71252.472002545.68230-1.0233038.6669036.51230K562DDX47
ESPL1ENSG00000135476.71422.876601884.28770-0.405205.864504.52500K562DKC1
ESPL1ENSG00000135476.71023.462301385.34130-0.436803.947202.32150K562DNAJC21
ESPL1ENSG00000135476.71629.973202322.00820-0.510509.680508.45980K562EIF2S2
ESPL1ENSG00000135476.7739.932001310.40840-0.824606.091004.56120K562EIF3A
ESPL1ENSG00000135476.71341.216401711.77070-0.351902.291001.35970K562EIF3D
ESPL1ENSG00000135476.71149.602501404.21190-0.288602.083801.36680K562EIF4A3
ESPL1ENSG00000135476.7699.62120905.87120-0.372702.984201.32370K562FASTKD2
ESPL1ENSG00000135476.7897.483801285.10070-0.517902.337101.31280K562FKBP4
ESPL1ENSG00000135476.7649.81630974.65040-0.584904.985803.71760K562FTO
ESPL1ENSG00000135476.71731.710801460.318300.245802.433301.85870K562FXR1
ESPL1ENSG00000135476.7253.33530768.57250-1.6011020.0648017.69270K562G3BP2
ESPL1ENSG00000135476.7695.339901078.72620-0.633507.112805.83880K562GPKOW
ESPL1ENSG00000135476.71756.842903094.24200-0.8166016.7538014.85140K562GRSF1
ESPL1ENSG00000135476.72013.832502454.75440-0.285602.650101.60020K562HNRNPA1
ESPL1ENSG00000135476.7717.339001479.17440-1.0441020.9147019.34990K562HNRNPC
ESPL1ENSG00000135476.71333.013301765.02920-0.405004.299001.95030K562HNRNPH1
ESPL1ENSG00000135476.7981.011801347.39450-0.457803.429202.38400K562HNRNPM
ESPL1ENSG00000135476.71313.998102220.89590-0.7572011.545609.94770K562HSPD1
ESPL1ENSG00000135476.7417.82890921.27220-1.140708.317706.59870K562KRR1
ESPL1ENSG00000135476.72716.921803669.54400-0.433605.103203.57390K562MSI2
ESPL1ENSG00000135476.71779.625302155.54570-0.276503.779802.84670K562MTPAP
ESPL1ENSG00000135476.71128.597301459.14400-0.370602.078001.33590K562NAA15
ESPL1ENSG00000135476.71455.708801859.61580-0.353302.821801.99160K562PPIG
ESPL1ENSG00000135476.7998.037901556.18900-0.640906.221305.09620K562PRPF8
ESPL1ENSG00000135476.72592.077703756.22060-0.535207.070605.76370K562PUF60
ESPL1ENSG00000135476.73331.976003995.52970-0.262002.904801.80940K562PUM1
ESPL1ENSG00000135476.73069.843803914.62420-0.350705.764804.36150K562PUM2
ESPL1ENSG00000135476.7339.40810733.30450-1.111408.078805.60080K562RAVER1
ESPL1ENSG00000135476.7622.743501584.82220-1.3476017.0247014.97960K562RPS19
ESPL1ENSG00000135476.72050.250202363.26220-0.205002.175201.44430K562SF3A3
ESPL1ENSG00000135476.7566.689201026.14950-0.856608.959607.13830K562SF3B1
ESPL1ENSG00000135476.7629.48590799.15090-0.344302.711701.86580K562SF3B4
ESPL1ENSG00000135476.7560.786801408.12890-1.328305.814204.79740K562SRSF1
ESPL1ENSG00000135476.71526.100401976.50430-0.373105.362903.71270K562SRSF7
ESPL1ENSG00000135476.71663.492202149.26890-0.369603.212301.72960K562SSRP1
ESPL1ENSG00000135476.71465.054001965.76090-0.424103.511902.07020K562STAU1
ESPL1ENSG00000135476.71033.552601506.13480-0.543205.007503.60590K562SUPV3L1
ESPL1ENSG00000135476.7427.63060754.44230-0.819004.553302.50980K562TAF15
ESPL1ENSG00000135476.71757.151301355.593100.374203.319202.26420K562TRIM56
ESPL1ENSG00000135476.7554.30120744.96350-0.426502.518401.48280K562U2AF1
ESPL1ENSG00000135476.7425.89690769.39600-0.8532012.0239010.32980K562U2AF2
ESPL1ENSG00000135476.71657.522202539.46750-0.6155017.0444015.42770K562UPF1
ESPL1ENSG00000135476.71538.212202172.94120-0.498406.630405.24210K562WDR3
ESPL1ENSG00000135476.71878.588702259.61310-0.266403.935602.93830K562WDR43
ESPL1ENSG00000135476.7989.526301672.81950-0.757504.318702.21960K562XRCC6
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ESPL1 is not available on ENCORE database.





7 RBPs can affect the splicing of ESPL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEESPL1ENSG00000135476.7chr12+536838685368399653683187536833785368413053684253-0.181000.002540.04412excludedK562SRSF1
SEESPL1ENSG00000135476.7chr12+536797075368069653677841536779515368175553682125-0.707000.000000.00000excludedK562SRSF1
SEESPL1ENSG00000135476.7chr12+536797075368069653677841536779515368175553682125-0.168000.000870.01083excludedK562AQR
SEESPL1ENSG00000135476.7chr12+536797075368069653677841536779515368175553682125-0.382000.001020.06022excludedHepG2FTO
SEESPL1ENSG00000135476.7chr12+536797075368069653677841536779515368175553682125-0.398000.000010.00176excludedHepG2SSB
A3SSESPL1ENSG00000135476.7chr12+5367084253671011536708665367101153670403536706430.160000.000370.00284longerK562AQR
A3SSESPL1ENSG00000135476.7chr12+5366857353668794536686005366879453666504536666410.246000.000000.00002longerK562AQR
A3SSESPL1ENSG00000135476.7chr12+5368230453682483536823215368248353681755536821250.066000.011230.05836longerK562AQR
A3SSESPL1ENSG00000135476.7chr12+536628075366334953663309536633495366247453662631-0.174000.003230.01966shorterK562AQR
A5SSESPL1ENSG00000135476.7chr12+5368658953686824536865895368675453687056536874190.078000.003260.05071longerK562AQR
A5SSESPL1ENSG00000135476.7chr12+5366253853662712536625385366263153662807536638690.216000.000110.01393longerK562SF3B4
A5SSESPL1ENSG00000135476.7chr12+5367125353671399536712535367139253671604536717440.359000.000230.01666longerK562SRSF1
A5SSESPL1ENSG00000135476.7chr12+5366253853662712536625385366263153662807536638690.107000.000170.09401longerK562PUM1
RIESPL1ENSG00000135476.7chr12+5368232153683087536823215368248353682873536830870.066000.002780.01869includedK562PUS1
RIESPL1ENSG00000135476.7chr12+5368232153683087536823215368248353682873536830870.172000.001780.03784includedK562SRSF1
RIESPL1ENSG00000135476.7chr12+5368232153683087536823215368248353682873536830870.174000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ESPL1 is not avaliable on ENCORE database.