EME2

General Information

Gene Name       : EME2
Gene ID             : ENSG00000197774.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EME2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EME2ENSG00000197774.120.501.400.95ENCSR000AEF
HepG2EME2ENSG00000197774.124.931.473.20ENCSR985KAT
K562EME2ENSG00000197774.123.862.353.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EME2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EME2 RNA is bound by 19 proteins.  







eCLIP assay for EME2 is not avaliable on ENCORE database.





19 proteins are bound to EME2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1618286621828750+3'-UTR4.002498.07504HepG2HNRNPK
chr1618284021828481+3'-UTR,intron-Proximal3.824426.49229HepG2SF3B4
chr1618262551826312+3'-UTR,5'-UTR4.176895.80295HepG2PPIG
chr1618288061828854+3'-UTR3.613855.03283HepG2RBFOX2
chr1618287501828796+3'-UTR3.973553.41442HepG2HNRNPK
chr1618307441830806+3'-UTR3.920667.58805HepG2HNRNPC
chr1618262581826325+3'-UTR,5'-UTR3.270515.63456HepG2RBFOX2
chr1618285331828632+3'-UTR3.634085.16259HepG2SRSF1
chr1618307471830804+3'-UTR3.227553.51117HepG2LSM11
chr1618271541827209+5'-UTR4.915294.65049HepG2SLTM
chr1618232231823330+5'-UTR,CDS4.273157.95933HepG2NCBP2
chr1618243401824383+CDS,intron-Proximal4.326588.96422HepG2PRPF8
chr1618252631825324+CDS,intron-Proximal3.420754.05505HepG2SF3B4
chr1618234361823469+CDS4.660685.27053HepG2PPIG
chr1618237311823826+CDS3.117694.11060HepG2SRSF1
chr1618232661823335+CDS3.519813.65452K562BUD13
chr1618254211825462+CDS,intron-Proximal3.440996.74268HepG2PRPF8
chr1618232641823350+CDS3.102899.66368HepG2PPIG
chr1618232481823328+CDS3.992244.41713HepG2SRSF1
chr1618253161825413+CDS,intron-Proximal3.5007410.35370HepG2PPIG
chr1618252661825345+CDS,intron-Proximal4.151404.59504K562RBFOX2
chr1618237151823842+CDS3.9560713.94981HepG2PPIG
chr1618232741823330+CDS3.299463.98124K562GEMIN5
chr1618232651823323+CDS3.406485.92454HepG2XRN2
chr1618252591825382+CDS,intron-Proximal4.256618.82190HepG2PRPF4
chr1618233281823386+CDS3.694953.21539HepG2SRSF1
chr1618255711825619+CDS4.738328.98365HepG2PPIG
chr1618234681823512+CDS,intron-Proximal3.294906.12954HepG2PRPF8
chr1618232441823369+CDS4.6652611.02823HepG2PRPF4
chr1618251701825271+CDS,intron-Proximal3.478243.49653K562PRPF8
chr1618252631825386+CDS,intron-Proximal4.2861114.41023HepG2RBFOX2
chr1618251721825247+CDS,intron-Proximal4.755165.23978HepG2PRPF4
chr1618258341825889+CDS4.133968.40792HepG2PPIG
chr1618251531825234+CDS,intron-Proximal4.8135511.68672HepG2RBFOX2
chr1618263901826468+intron-Distal,intron-Proximal4.049155.51270K562GTF2F1
chr1618239871824085+intron-Distal4.460483.99137K562NONO
chr1618245831824668+intron-Distal4.280316.73856HepG2XPO5
chr1618276691827748+intron-Distal4.899086.80961HepG2EFTUD2
chr1618263961826463+intron-Distal,intron-Proximal4.240144.09073K562SLTM
chr1618234861823590+intron-Distal,intron-Proximal3.309903.80158K562NONO
chr1618246731824713+intron-Distal3.572793.60408HepG2XPO5
chr1618263971826473+intron-Distal,intron-Proximal3.031434.29345HepG2PRPF4
chr1618239731824030+intron-Distal4.170853.71567HepG2RBFOX2
chr1618263971826462+intron-Distal,intron-Proximal3.965533.02711K562EWSR1
chr1618243831824436+intron-Proximal3.495089.04139HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EME2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EME2 is not available on ENCORE database.

  • 136 RBPs can affect the levels of EME2.  








The Knockdown/knockout RNA-Seq assay for EME2 is not available on ENCORE database.





136 RBPs can affect the gene expression of EME2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EME2ENSG00000197774.8602.73250384.324700.649104.174103.03300HepG2ABCF1
EME2ENSG00000197774.8229.00200389.77770-0.767307.640506.73230HepG2ACO1
EME2ENSG00000197774.8176.47330101.744200.794403.551102.43730HepG2ADAR
EME2ENSG00000197774.8543.94730197.394301.4623012.4669010.40160HepG2BCCIP
EME2ENSG00000197774.8475.71260171.499001.4718013.7671011.98560HepG2BCLAF1
EME2ENSG00000197774.8677.79870224.238101.5957026.0421024.51300HepG2BOP1
EME2ENSG00000197774.8364.06570237.794600.614402.245101.37600HepG2CCAR1
EME2ENSG00000197774.8500.20100389.674200.360102.745102.08120HepG2CKAP4
EME2ENSG00000197774.8193.4106099.469400.959203.803802.90050HepG2CNOT7
EME2ENSG00000197774.8410.56790205.851900.995908.282807.14580HepG2CPSF6
EME2ENSG00000197774.8185.83450104.334800.832704.437503.14840HepG2YBX3
EME2ENSG00000197774.8191.28700121.898800.650002.474201.45350HepG2CSTF2
EME2ENSG00000197774.8391.55350256.983600.607405.503904.50660HepG2DAZAP1
EME2ENSG00000197774.8457.04100360.479900.342302.538701.73700HepG2DDX19B
EME2ENSG00000197774.8171.66710104.485300.716203.008801.80510HepG2DDX1
EME2ENSG00000197774.8355.26160185.542000.937003.978303.17820HepG2DDX21
EME2ENSG00000197774.8250.56810146.991800.769403.652402.04850HepG2DDX28
EME2ENSG00000197774.8492.24680194.090601.3426011.4935010.04650HepG2DDX55
EME2ENSG00000197774.8350.39830242.221800.532602.931801.89340HepG2DDX5
EME2ENSG00000197774.8154.4966098.816300.644702.430501.51070HepG2DHX30
EME2ENSG00000197774.8533.68690372.906800.517104.471403.64760HepG2DKC1
EME2ENSG00000197774.8183.53600102.455900.841004.490003.61090HepG2DNAJC21
EME2ENSG00000197774.8286.46840101.541101.4962018.2593016.72500HepG2DNAJC2
EME2ENSG00000197774.8315.30180178.425700.821303.022902.06010HepG2EEF2
EME2ENSG00000197774.8233.62060148.684300.651802.792201.67790HepG2EFTUD2
EME2ENSG00000197774.8568.52230150.308001.9192027.4942025.76080HepG2EIF2S1
EME2ENSG00000197774.8673.21750166.075902.0191030.8074028.71930HepG2EIF4A3
EME2ENSG00000197774.8458.21220161.759401.5021010.072308.80020HepG2EIF4B
EME2ENSG00000197774.8759.08260520.487700.544306.368605.51870HepG2ETF1
EME2ENSG00000197774.8236.89450158.647100.578302.522401.77040HepG2FUBP3
EME2ENSG00000197774.8395.77980167.660701.2391011.043609.75290HepG2FXR1
EME2ENSG00000197774.8475.30900155.478801.6120018.9345017.26920HepG2G3BP1
EME2ENSG00000197774.8420.63240165.127401.3489013.3244011.38500HepG2G3BP2
EME2ENSG00000197774.8335.98420128.919901.3818012.4721010.67030HepG2GEMIN5
EME2ENSG00000197774.8214.7684092.084901.221604.294902.91230HepG2GRSF1
EME2ENSG00000197774.8332.80590103.437401.685808.914207.85070HepG2HNRNPA1
EME2ENSG00000197774.8377.55420115.051601.714303.701202.90920HepG2HNRNPC
EME2ENSG00000197774.8399.17810310.239300.363602.351401.68630HepG2HNRNPF
EME2ENSG00000197774.8425.98350234.083500.8637010.510509.27490HepG2HNRNPL
EME2ENSG00000197774.8362.76370114.291201.6662023.8860022.24260HepG2HNRNPU
EME2ENSG00000197774.8423.93190158.022701.4236014.3917012.98720HepG2IGF2BP2
EME2ENSG00000197774.8313.10680148.370601.077303.736702.59150HepG2IGF2BP3
EME2ENSG00000197774.8229.94660116.745200.977807.744406.58210HepG2ILF2
EME2ENSG00000197774.8176.5300094.808000.896703.907902.44550HepG2KHDRBS1
EME2ENSG00000197774.8325.74460158.977801.034805.553504.08120HepG2KHSRP
EME2ENSG00000197774.8783.62060251.389901.6401020.6550018.36900HepG2LARP4
EME2ENSG00000197774.8231.54110146.083500.664402.709901.58770HepG2LARP7
EME2ENSG00000197774.8270.82530153.285900.821003.092301.81060HepG2LIN28B
EME2ENSG00000197774.8570.55980167.719701.7662024.1478022.33030HepG2MAGOH
EME2ENSG00000197774.8466.46730168.642601.4677014.3810013.02370HepG2MATR3
EME2ENSG00000197774.8493.15560172.602201.5145015.6817014.25770HepG2NCBP2
EME2ENSG00000197774.8233.46920132.072700.821804.096602.35990HepG2NIP7
EME2ENSG00000197774.8501.04160304.094700.720304.215402.45580HepG2NKRF
EME2ENSG00000197774.8380.56250254.826000.578504.303403.35160HepG2NOL12
EME2ENSG00000197774.8178.04290104.343900.770802.854101.38050HepG2NOLC1
EME2ENSG00000197774.8468.07720178.281201.392508.565606.60300HepG2NONO
EME2ENSG00000197774.8415.12100292.889000.503102.966501.30550HepG2NUP35
EME2ENSG00000197774.8438.89510153.654601.5141014.2502012.64830HepG2PABPC4
EME2ENSG00000197774.8193.72300113.132900.775903.631502.67470HepG2PARN
EME2ENSG00000197774.8404.32310162.926301.3112015.3152014.07190HepG2PCBP1
EME2ENSG00000197774.8293.58100179.415200.710403.385302.23910HepG2PCBP2
EME2ENSG00000197774.8250.58350101.939201.2975011.7389010.28330HepG2PPIL4
EME2ENSG00000197774.8236.81590149.666100.661902.550501.77390HepG2PRPF8
EME2ENSG00000197774.8438.60010165.818501.4032017.8038016.64370HepG2PTBP1
EME2ENSG00000197774.8415.55490243.261900.772406.384005.52810HepG2PUF60
EME2ENSG00000197774.8578.73330258.242701.1641022.5432021.18520HepG2PUM1
EME2ENSG00000197774.8551.24450397.011100.473404.475303.72820HepG2PUS1
EME2ENSG00000197774.8319.07570179.511200.829703.749903.03950HepG2QKI
EME2ENSG00000197774.8281.43220394.08040-0.485703.133902.22610HepG2RBM15
EME2ENSG00000197774.8538.60720435.025700.308001.826001.38220HepG2RBM22
EME2ENSG00000197774.8331.92120162.946001.026305.221504.32220HepG2RBM25
EME2ENSG00000197774.8359.01150176.165501.027006.225304.72930HepG2RBM27
EME2ENSG00000197774.8353.68050143.055401.305808.870506.97960HepG2RCC2
EME2ENSG00000197774.8587.56880184.511001.6710031.5070030.10240HepG2NELFE
EME2ENSG00000197774.8460.70240171.899501.4222012.0870010.93590HepG2RECQL
EME2ENSG00000197774.8255.68180170.141300.587502.262101.40610HepG2RPS10
EME2ENSG00000197774.8363.79830140.938301.368008.020807.03740HepG2RPS19
EME2ENSG00000197774.8524.54470162.449501.6910020.7440018.72370HepG2RPS2
EME2ENSG00000197774.8426.6591099.909002.0943023.2568021.03890HepG2RPS3A
EME2ENSG00000197774.8185.24650101.783300.863804.904804.08800HepG2SAFB2
EME2ENSG00000197774.8246.07730141.396500.799303.418702.36930HepG2SERBP1
EME2ENSG00000197774.8381.46270548.00130-0.522602.847002.16220HepG2SF3A3
EME2ENSG00000197774.8377.60350172.575901.129509.079908.10320HepG2SF3B4
EME2ENSG00000197774.8363.12740233.269800.638405.489704.55890HepG2SLBP
EME2ENSG00000197774.8329.56040118.699901.4731018.4846017.04820HepG2SMN1
EME2ENSG00000197774.8134.20620245.21290-0.869603.638002.73750HepG2SNRNP70
EME2ENSG00000197774.8289.32790180.157400.683303.399702.88950HepG2SRSF1
EME2ENSG00000197774.8379.77820304.792700.317201.910801.32120HepG2SRSF7
EME2ENSG00000197774.8692.53550426.578000.699009.639608.79590HepG2SSB
EME2ENSG00000197774.8487.26640273.160500.8349010.344709.27120HepG2SUCLG1
EME2ENSG00000197774.8366.04290261.970100.482502.709001.77650HepG2SUPT6H
EME2ENSG00000197774.8314.87130193.197100.704602.921802.22940HepG2SUPV3L1
EME2ENSG00000197774.8232.41530129.482800.843803.999002.82640HepG2TFIP11
EME2ENSG00000197774.8446.93310111.067802.0085012.2352011.31360HepG2TIAL1
EME2ENSG00000197774.8336.46160112.047201.5862021.4757020.08990HepG2TRIM56
EME2ENSG00000197774.8406.21840237.672100.773206.357104.94630HepG2TUFM
EME2ENSG00000197774.8591.83140251.582401.2341012.1509010.35100HepG2UBE2L3
EME2ENSG00000197774.8312.60870114.115701.4538013.1227011.49780HepG2UCHL5
EME2ENSG00000197774.8609.94310485.991500.327602.504701.83450HepG2UPF1
EME2ENSG00000197774.8483.17890176.864201.4498011.207009.10950HepG2UPF2
EME2ENSG00000197774.8694.01320499.545700.474203.432002.27970HepG2UTP18
EME2ENSG00000197774.8199.9710089.490201.159903.820102.52570HepG2XPO5
EME2ENSG00000197774.8307.15050190.398200.689803.340902.17270HepG2XRCC6
EME2ENSG00000197774.8529.81150190.181801.4780015.2791013.60180HepG2XRN2
EME2ENSG00000197774.8273.61400173.041900.660903.116301.73450HepG2ZRANB2
EME2ENSG00000197774.8130.01450237.97390-0.872104.667803.96440K562AGGF1
EME2ENSG00000197774.8173.87420261.45740-0.588503.253802.16610K562AKAP8
EME2ENSG00000197774.81154.42760671.690000.7812011.674809.13400K562APOBEC3C
EME2ENSG00000197774.8494.42930305.918500.692504.351403.13050K562BCLAF1
EME2ENSG00000197774.8369.43890259.922100.507202.947901.85340K562CCAR1
EME2ENSG00000197774.8348.98190475.50210-0.446303.233901.59390K562CEBPZ
EME2ENSG00000197774.8341.40880246.309900.470902.494001.74760K562CPSF6
EME2ENSG00000197774.8660.76610935.88250-0.502203.288502.22450K562CELF1
EME2ENSG00000197774.8924.30480545.310100.7612013.0632011.75720K562DDX47
EME2ENSG00000197774.8403.06310262.800200.616903.420101.52320K562DDX51
EME2ENSG00000197774.8405.03780251.758600.685903.064301.71110K562EEF2
EME2ENSG00000197774.8382.84680243.201100.654503.570402.52520K562EFTUD2
EME2ENSG00000197774.8483.53200264.387200.870904.588003.26240K562EIF3A
EME2ENSG00000197774.8496.85680260.315100.932507.124505.34710K562EIF3D
EME2ENSG00000197774.8317.27640134.626501.2367011.8556010.18680K562EIF3G
EME2ENSG00000197774.8377.94980170.496701.148402.212201.47510K562EIF4A3
EME2ENSG00000197774.81243.27710761.210000.7077012.4690010.54760K562EIF4G2
EME2ENSG00000197774.865.74650119.02120-0.856202.931801.54760K562FUS
EME2ENSG00000197774.8603.97000177.308101.7681029.0395027.21540K562FXR1
EME2ENSG00000197774.827.6949060.00690-1.115502.443201.78510K562G3BP2
EME2ENSG00000197774.8362.06050243.833600.570202.880301.42470K562GEMIN5
EME2ENSG00000197774.890.93540235.24140-1.371204.004802.45200K562HNRNPA2B1
EME2ENSG00000197774.8556.00290247.992901.1647014.0187012.75860K562HNRNPC
EME2ENSG00000197774.8339.83480221.559200.617003.519202.22110K562HNRNPF
EME2ENSG00000197774.8651.61320492.769200.403002.861801.78370K562HNRNPL
EME2ENSG00000197774.8734.74950440.929800.736605.318304.06680K562HNRNPU
EME2ENSG00000197774.8341.57580551.42190-0.691005.440404.34180K562HSPD1
EME2ENSG00000197774.8177.82790262.81350-0.563602.911802.06360K562KIF1C
EME2ENSG00000197774.8281.65870105.124001.4218011.799109.97530K562MAGOH
EME2ENSG00000197774.8161.07590251.54930-0.643103.343302.12890K562MAK16
EME2ENSG00000197774.8269.34860104.898701.3604012.5860010.49540K562MATR3
EME2ENSG00000197774.8690.03580414.394100.735602.280301.54420K562MTPAP
EME2ENSG00000197774.898.76710206.35900-1.063104.833803.56240K562NAA15
EME2ENSG00000197774.857.97920102.79580-0.826202.761301.41290K562PCBP1
EME2ENSG00000197774.8553.30440367.816200.589003.871202.88760K562PCBP3
EME2ENSG00000197774.8471.39030282.119300.740506.675505.44180K562POLR2G
EME2ENSG00000197774.8393.55130236.664700.733604.490603.53590K562PRPF8
EME2ENSG00000197774.8267.01460102.140501.386309.123407.96410K562PTBP1
EME2ENSG00000197774.81103.24810830.548400.409503.780502.83050K562PUF60
EME2ENSG00000197774.8116.22100245.63430-1.079606.353505.56930K562PUS1
EME2ENSG00000197774.8157.73970239.27530-0.601103.195102.56550K562RBM15
EME2ENSG00000197774.8521.96790842.93870-0.691507.691305.08830K562RBM17
EME2ENSG00000197774.8230.2554097.897201.233809.238007.56010K562RBM22
EME2ENSG00000197774.8166.3488095.464200.801103.461101.85040K562RBM34
EME2ENSG00000197774.8351.95280203.028400.793605.727604.29330K562RCC2
EME2ENSG00000197774.8295.83760103.031301.5216014.6274012.15910K562NELFE
EME2ENSG00000197774.8509.99740241.011901.081303.654602.71280K562RPS19
EME2ENSG00000197774.8175.7579058.127101.596207.634005.85930K562RPS3
EME2ENSG00000197774.8488.06950251.401100.957009.705307.74970K562SAFB
EME2ENSG00000197774.874.68110216.22800-1.533704.613902.90280K562SNRNP200
EME2ENSG00000197774.878.20300138.86950-0.828403.270701.85830K562SSB
EME2ENSG00000197774.885.78890258.72750-1.592605.034702.90200K562SUPT6H
EME2ENSG00000197774.8329.26260229.039300.523502.295301.37450K562SUPV3L1
EME2ENSG00000197774.8527.17700282.984400.8975010.038808.46720K562SYNCRIP
EME2ENSG00000197774.8369.21420101.329701.8653023.0880020.62560K562TARDBP
EME2ENSG00000197774.8171.0543097.748900.807203.772702.79640K562TIA1
EME2ENSG00000197774.8582.66730794.89510-0.448104.482902.86220K562TROVE2
EME2ENSG00000197774.8633.45510434.402900.544106.204604.99090K562WDR43
EME2ENSG00000197774.8373.64660246.975100.597203.198201.86650K562XRN2
EME2ENSG00000197774.883.41290254.55730-1.609604.295102.10090K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EME2 is not available on ENCORE database.





2 RBPs can affect the splicing of EME2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A5SSEME2ENSG00000197774.8chr16+1825569182572718255691825685182579718259870.191000.002540.04144longerK562AQR
RIEME2ENSG00000197774.8chr16+182504118254091825041182513318253151825409-0.454000.000310.04457excludedK562HNRNPL
RIEME2ENSG00000197774.8chr16+1825041182540918250411825133182531518254090.329000.013130.06839includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EME2 is not avaliable on ENCORE database.