EIF2A

General Information

Gene Name : EIF2A
Gene ID : ENSG00000144895.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: EIF2A)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	EIF2A	ENSG00000144895.11	197.77	143.53	170.65	ENCSR000AEF
HepG2	EIF2A	ENSG00000144895.11	57.77	94.21	75.99	ENCSR985KAT
K562	EIF2A	ENSG00000144895.11	114.01	129.41	121.71	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
EIF2A	K562	CRISPR	BGKcLV13-25,BGKcLV13-26	BGKcLV13-1,BGKcLV13-2		NotSatisfied	ENCODE4
EIF2A	K562	CRISPR	BGKcLV13-27,BGKcLV13-28	BGKcLV13-1,BGKcLV13-2		NotSatisfied	ENCODE4
EIF2A	K562	CRISPR	BGKcLV15-17,BGKcLV15-18	BGKcLV15-1,BGKcLV15-2	Need discussion,	NotSatisfied	ENCODE4
EIF2A	K562	CRISPR	BGKcLV15-19,BGKcLV15-20	BGKcLV15-1,BGKcLV15-2	Need discussion,	NotSatisfied	ENCODE4
EIF2A	HepG2	CRISPR	BGHcLV14-25,BGHcLV14-26	BGHcLV14-1,BGHcLV14-2	0.0,0.0	NotSatisfied	ENCODE4
EIF2A	HepG2	CRISPR	BGHcLV14-27,BGHcLV14-28	BGHcLV14-1,BGHcLV14-2	0.0,0.0	NotSatisfied	ENCODE4
EIF2A	HepG2	CRISPR	BGHcLV16-19,BGHcLV16-20	BGHcLV16-1,BGHcLV16-2	0.0,0.0	NotSatisfied	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for EIF2A is not avaliable on ENCORE database.

Proteins bound to RNA

EIF2A RNA is bound by 15 proteins.

CanvasJS.com

eCLIP assay for EIF2A is not avaliable on ENCORE database.

15 proteins are bound to EIF2A RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr3	150301691	150301791	+	3'-UTR,CDS	4.60115	24.33549	HepG2	BCLAF1
chr3	150301934	150302014	+	3'-UTR	4.04237	20.58690	K562	PUM2
chr3	150280365	150280401	+	3'-UTR,CDS,intron-Distal	3.36390	16.48892	K562	YBX3
chr3	150280344	150280365	+	3'-UTR,CDS,intron-Distal	3.05846	13.43132	K562	YBX3
chr3	150283166	150283240	+	intron-Distal	3.68513	12.06787	HepG2	U2AF2
chr3	150290253	150290315	+	3'-UTR,CDS	4.00621	11.64153	HepG2	BCLAF1
chr3	150301638	150301691	+	3'-UTR,CDS	3.81491	11.46750	HepG2	BCLAF1
chr3	150285345	150285458	+	intron-Distal,intron-Proximal	3.08447	10.98868	K562	KHSRP
chr3	150282881	150282918	+	intron-Distal,intron-Proximal	3.68567	10.10950	K562	KHSRP
chr3	150280336	150280344	+	3'-UTR,CDS,intron-Distal,intron-Proximal	3.25118	9.91876	K562	YBX3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 50 entries

eCLIP assay for EIF2A is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for EIF2A is not available on ENCORE database.
120 RBPs can affect the levels of EIF2A.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for EIF2A is not available on ENCORE database.

120 RBPs can affect the gene expression of EIF2A :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
EIF2A	ENSG00000144895.7	1808.61140	4736.58620	-1.38900	86.45460	84.50950	HepG2	NELFE
EIF2A	ENSG00000144895.7	1248.23060	3562.78040	-1.51310	76.21000	74.23880	HepG2	RBM22
EIF2A	ENSG00000144895.7	850.23430	2394.72450	-1.49390	55.10980	53.41590	HepG2	TIAL1
EIF2A	ENSG00000144895.7	1077.10380	4682.73350	-2.12020	55.23850	52.77690	HepG2	DDX3X
EIF2A	ENSG00000144895.7	2007.30460	4256.04270	-1.08430	53.15080	51.41560	HepG2	PTBP1
EIF2A	ENSG00000144895.7	1289.42820	4439.33230	-1.78360	48.50380	46.09770	HepG2	NCBP2
EIF2A	ENSG00000144895.7	2438.16520	4625.12490	-0.92370	46.59100	45.16440	HepG2	SRSF1
EIF2A	ENSG00000144895.7	2320.48740	4262.64810	-0.87730	35.58150	33.86570	HepG2	ETF1
EIF2A	ENSG00000144895.7	931.26380	2230.38150	-1.26000	31.90930	30.17120	HepG2	HNRNPA1
EIF2A	ENSG00000144895.7	2566.01040	4411.45140	-0.78170	30.82530	29.17620	HepG2	RECQL
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 144 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for EIF2A is not available on ENCORE database.

20 RBPs can affect the splicing of EIF2A :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	is_included	Cell Line	Affected by RBP
SE	EIF2A	ENSG00000144895.7	chr3	+	150280343	150280447	150276174	150276249	150281301	150281401	-0.06600	excluded	K562	SF3B4
SE	EIF2A	ENSG00000144895.7	chr3	+	150293435	150293549	150285962	150286079	150299404	150299533	-0.05900	excluded	K562	AQR
SE	EIF2A	ENSG00000144895.7	chr3	+	150276174	150276249	150270140	150270212	150280328	150280447	-0.09700	excluded	K562	PUS1
SE	EIF2A	ENSG00000144895.7	chr3	+	150280328	150280447	150276174	150276249	150281301	150281401	-0.15400	excluded	K562	U2AF1
SE	EIF2A	ENSG00000144895.7	chr3	+	150276174	150276249	150270142	150270212	150280328	150280695	-0.07100	excluded	K562	HNRNPUL1
SE	EIF2A	ENSG00000144895.7	chr3	+	150276174	150276249	150270140	150270212	150280328	150280447	-0.07200	excluded	K562	UTP18
SE	EIF2A	ENSG00000144895.7	chr3	+	150280328	150280447	150276174	150276249	150281301	150281401	-0.08200	excluded	K562	U2AF2
SE	EIF2A	ENSG00000144895.7	chr3	+	150276174	150276249	150270140	150270212	150280328	150280447	-0.05600	excluded	K562	RBM15
SE	EIF2A	ENSG00000144895.7	chr3	+	150276174	150276249	150270142	150270212	150280328	150280695	-0.07100	excluded	K562	AGGF1
A3SS	EIF2A	ENSG00000144895.7	chr3	+	150285947	150286079	150285962	150286079	150285662	150285833	0.08500	longer	K562	AQR

Showing 1 to 10 of 41 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

EIF2A

General Information

Functions

Localization

Domains (AlphaFold: EIF2A)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for EIF2A is not avaliable on ENCORE database.

15 proteins are bound to EIF2A RNA:

eCLIP assay for EIF2A is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for EIF2A is not available on ENCORE database.

120 RBPs can affect the gene expression of EIF2A :

The Knockdown/knockout RNA-Seq assay for EIF2A is not available on ENCORE database.

20 RBPs can affect the splicing of EIF2A :

The Knockdown/knockout RNA-Seq assay for EIF2A is not avaliable on ENCORE database.