APP

General Information

Gene Name       : APP
Gene ID             : ENSG00000142192.20
Essential Gene : No

Functions

Localization

Domains (AlphaFold: APP)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878APPENSG00000142192.2055.6961.8658.77ENCSR000AEF
HepG2APPENSG00000142192.20141.17109.65125.41ENCSR985KAT
K562APPENSG00000142192.200.060.000.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for APP is not avaliable on ENCORE database.



Proteins bound to RNA
  • APP RNA is bound by 27 proteins.  







eCLIP assay for APP is not avaliable on ENCORE database.





27 proteins are bound to APP RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr212725354327253605-3'-UTR,intron-Distal,intron-Proximal3.005906.13103HepG2DDX6
chr212725354727253599-3'-UTR,intron-Distal,intron-Proximal3.895848.33996HepG2IGF2BP1
chr212725380227253867-3'-UTR,intron-Distal,intron-Proximal4.391845.79075HepG2IGF2BP3
chr212725320827253269-3'-UTR,intron-Distal3.051796.60473HepG2RBFOX2
chr212725393927253992-3'-UTR,CDS,intron-Distal3.183064.82195HepG2ZNF800
chr212725308027253106-3'-UTR,intron-Distal3.352763.77853HepG2IGF2BP1
chr212725317327253245-3'-UTR,intron-Distal3.787679.53035HepG2DDX6
chr212725395627253996-3'-UTR,CDS,intron-Distal4.093825.96402HepG2RPS3
chr212725342327253481-3'-UTR,intron-Distal4.039556.98813HepG2TIAL1
chr212725320327253265-3'-UTR,intron-Distal4.2858215.43174HepG2IGF2BP1
chr212725317427253246-3'-UTR,intron-Distal3.4789014.11806HepG2DDX55
chr212725391227253934-3'-UTR,intron-Distal4.354613.73296HepG2IGF2BP1
chr212725390327253996-3'-UTR,CDS,intron-Distal4.168645.99887HepG2IGF2BP3
chr212725302027253056-3'-UTR,intron-Distal4.302994.94157HepG2IGF2BP1
chr212725351327253603-3'-UTR,intron-Distal,intron-Proximal3.037735.65145HepG2TIA1
chr212725393427253992-3'-UTR,CDS,intron-Distal4.6400814.62433HepG2IGF2BP1
chr212725376827253860-3'-UTR,intron-Distal,intron-Proximal3.358964.45128HepG2HNRNPL
chr212725319527253261-3'-UTR,intron-Distal5.206587.57470HepG2IGF2BP3
chr212725339227253470-3'-UTR,intron-Distal4.179714.36138HepG2TIA1
chr212725333327253392-3'-UTR,intron-Distal3.789473.82363HepG2TIA1
chr212725319127253261-3'-UTR,intron-Distal3.149497.36943HepG2FAM120A
chr212725339427253460-3'-UTR,intron-Distal4.191454.61003HepG2IGF2BP3
chr212725310627253119-3'-UTR,intron-Distal3.161093.13437HepG2IGF2BP1
chr212748440227484447-5'-UTR,CDS,intron-Distal,intron-Proximal4.5100211.19306HepG2RPS3
chr212754298827543082-5'-UTR,intron-Distal,intron-Proximal4.3898851.40459HepG2DDX3X
chr212754295927543077-5'-UTR,intron-Distal,intron-Proximal3.001988.77312HepG2SDAD1
chr212748445127484464-5'-UTR,CDS,intron-Distal,intron-Proximal4.8848124.32080HepG2DDX3X
chr212748440027484451-5'-UTR,CDS,intron-Distal,intron-Proximal4.7130334.01147HepG2DDX3X
chr212754299827543081-5'-UTR,intron-Distal,intron-Proximal3.7152414.40474HepG2RPS3
chr212754288027542988-5'-UTR,CDS,intron-Distal,intron-Proximal3.9394924.77812HepG2GRWD1
chr212748444827484463-5'-UTR,CDS,intron-Distal,intron-Proximal3.127828.45480HepG2GRWD1
chr212748444727484464-5'-UTR,CDS,intron-Distal,intron-Proximal3.8661610.76238HepG2RPS3
chr212748439127484448-5'-UTR,CDS,intron-Distal,intron-Proximal3.639649.55915HepG2GRWD1
chr212754293727542988-5'-UTR,CDS,intron-Distal,intron-Proximal3.7751525.26193HepG2DDX3X
chr212754288027542940-5'-UTR,CDS,intron-Distal4.3403220.16147HepG2RPS3
chr212734739827347414-CDS,intron-Distal,intron-Proximal4.6379819.12916HepG2SND1
chr212739430127394323-CDS,intron-Distal3.772968.24547HepG2SND1
chr212728420427284262-CDS,intron-Distal4.379624.13513HepG2LIN28B
chr212735465627354716-CDS,intron-Distal,intron-Proximal3.7189422.77001HepG2SND1
chr212746230827462338-CDS,intron-Distal4.933757.48847HepG2GRWD1
chr212735465627354712-CDS,intron-Distal,intron-Proximal3.172106.46352HepG2LIN28B
chr212737244427372485-CDS,intron-Distal3.9434712.52977HepG2SND1
chr212728409527284168-CDS,intron-Distal3.9697625.16991HepG2SND1
chr212739415527394178-CDS,intron-Distal,intron-Proximal3.362544.48593HepG2FTO
chr212734830627348338-CDS,intron-Distal,intron-Proximal4.020698.19556HepG2BCLAF1
chr212728405227284078-CDS,intron-Distal,intron-Proximal4.4961222.49749HepG2SND1
chr212748434927484402-CDS,intron-Distal,intron-Proximal5.0970311.07772HepG2RPS3
chr212737235927372404-CDS,intron-Distal3.8478215.34970HepG2SND1
chr212734746527347542-CDS,intron-Distal,intron-Proximal3.3549514.17045HepG2BCLAF1
chr212732804227328069-CDS,intron-Distal3.126993.50792HepG2ZNF800
chr212739415427394166-CDS,intron-Distal,intron-Proximal3.163364.50748HepG2GRWD1
chr212754287927542937-CDS,intron-Distal4.7981772.08537HepG2DDX3X
chr212726403327264049-CDS,intron-Distal,intron-Proximal3.9607016.61313HepG2SND1
chr212742555127425582-CDS,intron-Distal,intron-Proximal4.4753620.59139HepG2SND1
chr212734738227347398-CDS,intron-Distal,intron-Proximal5.0090023.11120HepG2SND1
chr212737242627372496-CDS,intron-Distal3.7540715.59767HepG2BCLAF1
chr212732794727328024-CDS,intron-Distal4.0459217.70371HepG2SND1
chr212742333727423409-CDS,intron-Distal,intron-Proximal3.026889.00189HepG2BCLAF1
chr212739416627394224-CDS,intron-Distal,intron-Proximal3.1998411.82658HepG2GRWD1
chr212732690327326966-CDS,intron-Distal,intron-Proximal3.4618917.88965HepG2SND1
chr212737232927372358-CDS,intron-Distal,intron-Proximal4.3813310.74047HepG2GRWD1
chr212739422027394268-CDS,intron-Distal,intron-Proximal3.7726724.14462HepG2BCLAF1
chr212739416827394208-CDS,intron-Distal,intron-Proximal4.1126314.81576HepG2SND1
chr212728407827284095-CDS,intron-Distal4.5056428.23719HepG2SND1
chr212734741427347452-CDS,intron-Distal,intron-Proximal3.4547418.39872HepG2SND1
chr212726407527264157-CDS,intron-Distal,intron-Proximal3.515808.03230HepG2ZNF800
chr212739419827394328-CDS,intron-Distal,intron-Proximal3.102968.13023HepG2SDAD1
chr212742340127423421-CDS,intron-Distal,intron-Proximal4.130398.59673HepG2SND1
chr212737234727372420-CDS,intron-Distal3.448329.68982HepG2ZNF800
chr212734741727347460-CDS,intron-Distal,intron-Proximal3.432025.60408HepG2ZNF800
chr212734828527348300-CDS,intron-Distal4.450118.41475HepG2BCLAF1
chr212748433327484386-CDS,intron-Distal3.678989.49961HepG2GRWD1
chr212727733527277385-CDS,intron-Distal,intron-Proximal4.1349144.75017HepG2SND1
chr212725401927254082-CDS,intron-Distal3.139254.99723HepG2IGF2BP1
chr212728406127284134-CDS,intron-Distal4.522498.09380HepG2RPS3
chr212746230227462322-CDS,intron-Distal4.291325.27247HepG2RPS3
chr212725401827254073-CDS,intron-Distal3.8223936.45310HepG2SND1
chr212742332727423411-CDS,intron-Distal,intron-Proximal5.656448.82609HepG2ZNF800
chr212746233827462381-CDS,intron-Distal,intron-Proximal3.220797.87063HepG2GRWD1
chr212725403027254084-CDS,intron-Distal4.6359712.28002HepG2RPS3
chr212748431727484406-CDS,intron-Distal,intron-Proximal3.812317.44969HepG2FASTKD2
chr212748429527484333-CDS,intron-Distal,intron-Proximal3.242088.10388HepG2GRWD1
chr212742331627423385-CDS,intron-Distal,intron-Proximal3.8274529.78741HepG2SND1
chr212734826627348285-CDS,intron-Distal,intron-Proximal3.886067.65975HepG2BCLAF1
chr212739415727394349-CDS,intron-Distal,intron-Proximal3.4675332.83520HepG2FXR2
chr212742342127423478-CDS,intron-Distal,intron-Proximal4.4785221.70494HepG2SND1
chr212726409327264144-CDS,intron-Distal,intron-Proximal4.128127.55572HepG2RPS3
chr212739417127394220-CDS,intron-Distal,intron-Proximal3.8731715.80228HepG2BCLAF1
chr212737232927372355-CDS,intron-Distal,intron-Proximal4.9496711.75511HepG2SND1
chr212739428527394359-CDS,intron-Distal,intron-Proximal4.9167422.82155HepG2TRA2A
chr212725407327254082-CDS,intron-Distal3.8302220.82661HepG2SND1
chr212739421527394224-CDS,intron-Distal,intron-Proximal3.557587.54912HepG2SND1
chr212742555227425623-CDS,intron-Distal3.399768.03770HepG2GRWD1
chr212726408727264137-CDS,intron-Distal,intron-Proximal3.7175324.09105HepG2SND1
chr212739426827394350-CDS,intron-Distal3.7223224.15551HepG2BCLAF1
chr212742558227425616-CDS,intron-Distal5.1642019.89982HepG2SND1
chr212739416827394204-CDS,intron-Distal,intron-Proximal3.542043.10693HepG2UCHL5
chr212735465627354706-CDS,intron-Distal,intron-Proximal3.6243110.26109HepG2BCLAF1
chr212734746027347540-CDS,intron-Distal,intron-Proximal4.3697011.35955HepG2ZNF800
chr212742344827423464-CDS,intron-Distal,intron-Proximal3.539114.34695HepG2BCLAF1
chr212737238027372409-CDS,intron-Distal3.441848.80587HepG2GRWD1
chr212739415227394348-CDS,intron-Distal,intron-Proximal3.3929232.34313HepG2ZNF800
chr212742562327425663-CDS,intron-Distal3.269857.33264HepG2GRWD1
chr212735476927354789-CDS,intron-Distal3.5745110.93821HepG2SND1
chr212732804427328069-CDS,intron-Distal5.8807622.69923HepG2SND1
chr212739418627394285-CDS,intron-Distal,intron-Proximal3.9880811.51503HepG2TRA2A
chr212726997027269985-CDS,intron-Distal3.241329.17063HepG2SND1
chr212746225827462278-CDS,intron-Distal,intron-Proximal3.067324.12887HepG2GRWD1
chr212737235827372380-CDS,intron-Distal4.1011212.39122HepG2GRWD1
chr212732690327326962-CDS,intron-Distal,intron-Proximal3.350183.07643HepG2LIN28B
chr212727733827277385-CDS,intron-Distal3.284418.46940HepG2RPS3
chr212734828127348330-CDS,intron-Distal,intron-Proximal3.952017.03378HepG2GRWD1
chr212742349327423509-CDS,intron-Distal3.305798.38040HepG2SND1
chr212739422427394267-CDS,intron-Distal,intron-Proximal3.6398120.92614HepG2SND1
chr212739415527394171-CDS,intron-Distal,intron-Proximal4.715079.30195HepG2BCLAF1
chr212734831227348332-CDS,intron-Distal,intron-Proximal3.500618.87034HepG2SND1
chr212739422427394274-CDS,intron-Distal,intron-Proximal3.3035715.92603HepG2GRWD1
chr212753210127532153-intron-Distal4.219383.62366HepG2HNRNPM
chr212754177527541850-intron-Distal,intron-Proximal4.080914.03786HepG2NKRF
chr212734209727342164-intron-Distal4.280444.51355HepG2PTBP1
chr212737205927372132-intron-Distal3.741533.14375HepG2RBFOX2
chr212739718127397293-intron-Distal3.899103.05187HepG2QKI
chr212754176627541844-intron-Distal,intron-Proximal3.053554.90123HepG2CSTF2T
chr212738140927381507-intron-Distal4.665694.17759HepG2QKI
chr212737217127372257-intron-Distal,intron-Proximal3.560063.35585HepG2QKI
chr212753032927530386-intron-Distal3.462093.66782HepG2HNRNPM
chr212737582027375919-intron-Distal4.042033.45317HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for APP is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for APP is not available on ENCORE database.

  • 132 RBPs can affect the levels of APP.  








The Knockdown/knockout RNA-Seq assay for APP is not available on ENCORE database.





132 RBPs can affect the gene expression of APP :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
APPENSG00000142192.1610887.264707711.821200.497407.387705.73370HepG2AATF
APPENSG00000142192.166149.3115011561.39140-0.9108016.6851014.73370HepG2ABCF1
APPENSG00000142192.165592.558707635.13380-0.449105.025803.73750HepG2ADAR
APPENSG00000142192.1632307.3112012566.333101.3622030.7683029.23540HepG2AKAP1
APPENSG00000142192.1621552.0391015924.664100.436503.981802.73750HepG2AKAP8
APPENSG00000142192.1614116.542609352.280000.5939022.0669020.20570HepG2AKAP8L
APPENSG00000142192.1622122.6934010601.063901.0612071.6464069.09430HepG2AUH
APPENSG00000142192.169800.069508288.427900.241602.082901.55850HepG2BOP1
APPENSG00000142192.1610632.829108660.753500.295902.968701.69560HepG2BUD13
APPENSG00000142192.1613104.130108517.790700.6214014.8236013.28810HepG2CALR
APPENSG00000142192.166350.107109878.31350-0.637509.244607.90220HepG2CIRBP
APPENSG00000142192.1629336.0831017422.696100.751606.311905.15760HepG2CNOT7
APPENSG00000142192.1614755.837407609.240000.9554022.6617020.93180HepG2CPSF6
APPENSG00000142192.1615538.568109519.420100.7068013.7245011.50050HepG2CPSF7
APPENSG00000142192.163101.344003968.54290-0.355703.372602.19410HepG2CSTF2
APPENSG00000142192.1619394.7122010726.714000.8544040.5360038.65980HepG2CELF1
APPENSG00000142192.1613485.3778011532.997500.225505.836604.81600HepG2DAZAP1
APPENSG00000142192.166415.506608609.10870-0.4243013.7429012.18820HepG2DDX19B
APPENSG00000142192.165207.476008511.17940-0.7088014.1896012.79480HepG2DDX21
APPENSG00000142192.165453.310408326.60400-0.6106013.0097011.09020HepG2DDX24
APPENSG00000142192.163879.171905910.47800-0.607506.078904.25560HepG2DDX27
APPENSG00000142192.1616359.2870012037.224600.442504.499903.71690HepG2DDX3X
APPENSG00000142192.1615929.4952020550.71480-0.367504.234902.64990HepG2DDX47
APPENSG00000142192.1613731.706808640.847200.668204.220403.02790HepG2DDX59
APPENSG00000142192.167718.691609513.80530-0.301702.647501.65530HepG2DDX5
APPENSG00000142192.1632268.7118010341.100401.6416043.4853041.48160HepG2DDX6
APPENSG00000142192.163704.813508905.82110-1.2653088.7397086.40210HepG2DKC1
APPENSG00000142192.169910.996007688.174000.366307.191606.10130HepG2DNAJC21
APPENSG00000142192.165508.934808038.52940-0.545207.195505.78270HepG2EEF2
APPENSG00000142192.168266.539806701.043700.302802.565901.49490HepG2EFTUD2
APPENSG00000142192.1648317.586109940.281802.2811096.8117093.95530HepG2EIF2S1
APPENSG00000142192.168093.601206525.329900.310602.763901.86130HepG2EIF3D
APPENSG00000142192.165034.835408035.94040-0.6745015.6170013.48630HepG2EIF3G
APPENSG00000142192.1620183.9489010696.007300.9160011.3588010.01100HepG2EIF4B
APPENSG00000142192.168515.8780011378.74540-0.4181011.045309.59180HepG2EIF4G1
APPENSG00000142192.1613390.3868010899.977800.296802.814701.99510HepG2EIF4G2
APPENSG00000142192.166556.8083010014.04050-0.6110010.271508.37980HepG2ESF1
APPENSG00000142192.1614820.2351012170.819900.284002.939002.32280HepG2ETF1
APPENSG00000142192.1610935.509609096.102900.265602.775701.93950HepG2EWSR1
APPENSG00000142192.167562.674905832.349900.374705.649803.93670HepG2FAM120A
APPENSG00000142192.1610383.141708109.675200.356404.334302.94990HepG2FASTKD2
APPENSG00000142192.1621706.4066011673.887200.8947014.8382013.29070HepG2FIP1L1
APPENSG00000142192.1614746.874109918.187300.572204.542203.13420HepG2FUS
APPENSG00000142192.1623180.6813010281.768701.1727024.9280023.01190HepG2G3BP1
APPENSG00000142192.166516.9189010916.28990-0.7442012.3225010.45150HepG2G3BP2
APPENSG00000142192.165852.926408625.69840-0.559506.283405.34530HepG2GPKOW
APPENSG00000142192.1615730.873709347.536500.750806.627904.37170HepG2GTF2F1
APPENSG00000142192.1611111.968708887.019000.322206.962405.50320HepG2HDGF
APPENSG00000142192.163131.602807761.82970-1.3095046.0955044.11890HepG2HNRNPA1
APPENSG00000142192.1621462.9210014388.235700.576905.395803.39310HepG2HNRNPAB
APPENSG00000142192.1610846.951608633.627800.329203.608602.82460HepG2HNRNPC
APPENSG00000142192.1610172.2464015091.60180-0.569104.698102.72400HepG2HNRNPD
APPENSG00000142192.1610681.320309260.714000.205803.412702.62240HepG2HNRNPF
APPENSG00000142192.1616855.7820010412.784500.6948012.7465011.35730HepG2HNRNPK
APPENSG00000142192.1617241.2334010505.419000.7146052.4292049.98330HepG2HNRNPL
APPENSG00000142192.169669.698608576.545400.173002.620202.03060HepG2HNRNPU
APPENSG00000142192.167440.289609119.20930-0.293503.562102.74880HepG2IGF2BP1
APPENSG00000142192.1618765.088209808.729100.935804.936503.63860HepG2IGF2BP3
APPENSG00000142192.1611173.806608760.652600.3509013.0943011.63150HepG2ILF2
APPENSG00000142192.1612199.8709016985.51870-0.477403.260801.80970HepG2ILF3
APPENSG00000142192.1612066.4461016603.20860-0.460503.685702.27780HepG2KHDRBS1
APPENSG00000142192.168113.4503010512.32020-0.373702.467601.53050HepG2KHSRP
APPENSG00000142192.1610524.938008509.194600.306609.167707.40440HepG2KIF1C
APPENSG00000142192.166885.427808814.96210-0.356403.777602.35790HepG2LIN28B
APPENSG00000142192.165923.1871011088.30940-0.9046016.1478014.62600HepG2MAGOH
APPENSG00000142192.166844.9871011150.16250-0.703909.142408.04960HepG2MATR3
APPENSG00000142192.1614834.058306829.230101.119005.813004.33530HepG2METAP2
APPENSG00000142192.1612461.419707932.680900.6515012.290709.78760HepG2NAA15
APPENSG00000142192.1616230.9804011412.643000.508005.524904.64430HepG2NCBP2
APPENSG00000142192.164698.444507298.91770-0.6355010.706309.31270HepG2NSUN2
APPENSG00000142192.1617990.7829010162.930100.8238013.6338012.05760HepG2PABPC4
APPENSG00000142192.1613614.096108489.277500.6813028.7574026.59600HepG2PARN
APPENSG00000142192.166628.993907649.58850-0.206602.481401.77930HepG2PPIL4
APPENSG00000142192.169487.7631010624.39700-0.163202.178601.68200HepG2PTBP1
APPENSG00000142192.1619529.1397011589.191300.7527060.2003058.19590HepG2PUM1
APPENSG00000142192.1616053.7011011580.554100.471109.750608.53090HepG2PUM2
APPENSG00000142192.167033.869109481.44300-0.4308014.0937012.89130HepG2PUS1
APPENSG00000142192.1615371.0965011505.958800.417708.537107.53130HepG2QKI
APPENSG00000142192.1612987.547609060.002300.519402.911502.18990HepG2RAVER1
APPENSG00000142192.1618081.4839012197.441600.5678013.4733011.79580HepG2RBM15
APPENSG00000142192.1621320.7160010172.682601.0675059.3536057.57400HepG2RBM22
APPENSG00000142192.164408.618108220.36900-0.8989015.7592013.33560HepG2RCC2
APPENSG00000142192.166938.4823011823.72900-0.7690036.6380035.14890HepG2NELFE
APPENSG00000142192.167765.1339011012.56830-0.5041016.9845015.66900HepG2RECQL
APPENSG00000142192.167122.570909336.19330-0.390404.144103.17340HepG2RPS2
APPENSG00000142192.168347.0136017496.79030-1.0678015.1922013.37640HepG2RPS3A
APPENSG00000142192.1612763.538104820.418701.4047033.4106031.29290HepG2RRP9
APPENSG00000142192.169480.1425016620.26120-0.810007.073804.73860HepG2SBDS
APPENSG00000142192.168162.905206372.538100.357103.559102.48890HepG2SERBP1
APPENSG00000142192.1619169.021009590.446600.9990013.6476012.08280HepG2SF3A3
APPENSG00000142192.167903.2670011060.92650-0.4850015.6464014.41660HepG2SF3B4
APPENSG00000142192.1611681.148608906.911400.3911016.6628015.28830HepG2SMN1
APPENSG00000142192.1616664.815409240.267700.850709.698507.83330HepG2SMNDC1
APPENSG00000142192.1615855.061509065.778100.806307.731106.41820HepG2SNRNP70
APPENSG00000142192.1620746.4542011489.899200.8524028.7084027.53620HepG2SRFBP1
APPENSG00000142192.167951.138306016.473400.402103.691001.82990HepG2SRP68
APPENSG00000142192.166721.7492011545.39310-0.7804044.0359042.64800HepG2SRSF1
APPENSG00000142192.1613407.581008766.939300.612806.303004.73440HepG2SRSF3
APPENSG00000142192.1616703.4776010779.313300.6318027.3484025.66590HepG2SRSF5
APPENSG00000142192.1610928.093609098.173700.264305.185304.28000HepG2SRSF7
APPENSG00000142192.1610881.783209392.947700.212203.935903.30130HepG2SRSF9
APPENSG00000142192.163073.838909976.35190-1.6985057.9875056.39120HepG2SSB
APPENSG00000142192.1612899.056508466.915900.607304.845303.24670HepG2SUB1
APPENSG00000142192.1610333.6899012258.76510-0.246505.691004.85790HepG2SUCLG1
APPENSG00000142192.1612700.5635017492.72080-0.461903.491501.98280HepG2SUGP2
APPENSG00000142192.1612734.695307881.471600.6921015.0803013.02460HepG2SUPT6H
APPENSG00000142192.164862.096406288.31870-0.371102.952802.25760HepG2SUPV3L1
APPENSG00000142192.168189.0790010377.95030-0.341706.166105.38530HepG2TAF15
APPENSG00000142192.1614888.467708023.235100.8918020.6679019.02880HepG2TARDBP
APPENSG00000142192.1610673.5069016968.63200-0.668803.238402.08490HepG2TBRG4
APPENSG00000142192.167905.039004214.855800.9072014.5749012.66180HepG2TFIP11
APPENSG00000142192.1612819.261609535.391100.426806.992305.67100HepG2TIA1
APPENSG00000142192.163854.421608333.61390-1.1124043.9799042.43200HepG2TIAL1
APPENSG00000142192.1613940.016508408.220500.7293034.9646033.24240HepG2TRIM56
APPENSG00000142192.1618669.797609985.390900.9027013.7487012.31170HepG2U2AF1
APPENSG00000142192.1625173.8991010791.523101.221904.709203.39740HepG2U2AF2
APPENSG00000142192.165452.941103714.721500.553706.609905.42390HepG2UCHL5
APPENSG00000142192.1611512.495208505.260900.4367014.2294012.87910HepG2UPF1
APPENSG00000142192.163851.802105758.24440-0.580104.391603.10920HepG2UPF2
APPENSG00000142192.1611685.9922015672.01630-0.423402.771901.67320HepG2XPO5
APPENSG00000142192.162439.574606190.15930-1.3433035.0563032.66390HepG2XRN2
APPENSG00000142192.169076.274506934.620700.3882010.981109.79340HepG2ZC3H8
APPENSG00000142192.1626540.927609354.157401.50440230.03180227.36210HepG2ZNF622
APPENSG00000142192.1625.082004.753302.399602.878502.28070K562AQR
APPENSG00000142192.1616.034401.124503.833702.963002.14070K562HSPD1
APPENSG00000142192.168.7818054.78640-2.641207.285406.02600K562MTPAP
APPENSG00000142192.166.2873060.86760-3.2752010.351109.03330K562NSUN2
APPENSG00000142192.161.0655056.16400-5.7200015.0240012.14230K562NUFIP2
APPENSG00000142192.16147.090701.138907.0128034.1445031.57170K562PRPF8
APPENSG00000142192.163.7208060.06820-4.0129012.8580011.20310K562SF3A3
APPENSG00000142192.1669.6886010.343402.752108.157506.42740K562SF3B1
APPENSG00000142192.165.6344061.54180-3.4492011.308809.57370K562SRPK2
APPENSG00000142192.165.6267064.53960-3.5198012.4115011.02740K562UPF1
APPENSG00000142192.162.6044055.22380-4.4062012.7470010.81400K562WDR3
APPENSG00000142192.161.5468057.43080-5.2145015.7396013.94380K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for APP is not available on ENCORE database.





25 RBPs can affect the splicing of APP :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902737232927372497-0.143000.000000.00039excludedHepG2RBM22
SEAPPENSG00000142192.16chr21-273482782734834127347382273475412735465627354790-0.052000.002460.04304excludedHepG2U2AF1
SEAPPENSG00000142192.16chr21-273723292737249727354656273547902739415527394358-0.073000.000000.00003excludedHepG2HNRNPM
SEAPPENSG00000142192.16chr21-2736967427369731273546562735479027372329273724970.171000.000000.00000includedHepG2HNRNPK
SEAPPENSG00000142192.16chr21-273723292737249727354656273547902739415527394358-0.067000.000000.00000excludedHepG2QKI
SEAPPENSG00000142192.16chr21-2736967427369731273546562735479027394155273943580.075000.003120.03619includedHepG2U2AF2
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902739415527394358-0.132000.000010.00112excludedHepG2AKAP1
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902739415527394358-0.119000.000080.05172excludedHepG2FAM120A
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902737232927372497-0.125000.000060.00706excludedHepG2NCBP2
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902739415527394358-0.103000.000240.06460excludedHepG2EFTUD2
SEAPPENSG00000142192.16chr21-2736967427369731273546562735479027372329273724970.120000.000130.01010includedHepG2SFPQ
SEAPPENSG00000142192.16chr21-273723292737249727354656273547902739415527394358-0.071000.000000.00000excludedHepG2PTBP1
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902737232927372497-0.181000.000010.00239excludedHepG2HNRNPA1
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902737232927372497-0.138000.000030.00658excludedHepG2PCBP2
SEAPPENSG00000142192.16chr21-273723292737249727354656273547902739415527394358-0.067000.000000.00000excludedHepG2SF3A3
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902737232927372497-0.147000.000000.00001excludedHepG2RBFOX2
SEAPPENSG00000142192.16chr21-2736967427369731273546562735479027372329273724970.119000.000380.02254includedHepG2PCBP1
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902739415527394358-0.132000.000020.00200excludedHepG2SF3B4
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902739415527394358-0.094000.001690.06404excludedHepG2HNRNPU
SEAPPENSG00000142192.16chr21-273696742736973127354656273547902739415527394358-0.119000.000010.00319excludedHepG2XRCC6
MXEAPPENSG00000142192.16chr21-27369674273697312737232927372497273546562735479027394155273943580.120000.000360.048801includedHepG2HNRNPA1
MXEAPPENSG00000142192.16chr21-27369674273697312737232927372497273546562735479027394155273943580.087000.000010.001411includedHepG2PTBP1
MXEAPPENSG00000142192.16chr21-2736967427369731273723292737249727354656273547902739415527394358-0.142000.000000.000022includedHepG2TAF15
MXEAPPENSG00000142192.16chr21-2736967427369731273723292737249727354656273547902739415527394358-0.155000.000000.000002includedHepG2SRSF9
MXEAPPENSG00000142192.16chr21-2736967427369731273723292737249727354656273547902739415527394358-0.126000.000000.001112includedHepG2TIA1
MXEAPPENSG00000142192.16chr21-27369674273697312737232927372497273546562735479027394155273943580.107000.000000.000011includedHepG2SF3A3
MXEAPPENSG00000142192.16chr21-2736967427369731273723292737249727354656273547902739415527394358-0.067000.000740.012362includedHepG2SFPQ
MXEAPPENSG00000142192.16chr21-2736967427369731273723292737249727354656273547902739415527394358-0.076000.006410.096272includedHepG2DDX55
MXEAPPENSG00000142192.16chr21-2736967427369731273723292737249727354656273547902739415527394358-0.143000.000000.000072includedHepG2PCBP1
MXEAPPENSG00000142192.16chr21-27369674273697312737232927372497273546562735479027394155273943580.059000.000060.004541includedHepG2RBFOX2
MXEAPPENSG00000142192.16chr21-2736967427369731273723292737249727354656273547902739415527394358-0.106000.000020.001012includedHepG2HNRNPK
MXEAPPENSG00000142192.16chr21-2736967427369731273723292737249727354656273547902739415527394358-0.107000.000290.013862includedHepG2SUPV3L1
MXEAPPENSG00000142192.16chr21-27369674273697312737232927372497273546562735479027394155273943580.076000.000130.007191includedHepG2NCBP2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for APP is not avaliable on ENCORE database.