TUBB6

General Information

Gene Name       : TUBB6
Gene ID             : ENSG00000176014.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TUBB6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TUBB6ENSG00000176014.1221.4537.4229.44ENCSR000AEF
HepG2TUBB6ENSG00000176014.1243.1916.7729.98ENCSR985KAT
K562TUBB6ENSG00000176014.1279.1747.2463.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TUBB6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TUBB6 RNA is bound by 7 proteins.  







eCLIP assay for TUBB6 is not avaliable on ENCORE database.





7 proteins are bound to TUBB6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr181232624112326357+3'-UTR,intron-Distal4.3307816.43977K562YBX3
chr181232505412325105+3'-UTR,CDS,intron-Distal,intron-Proximal3.374365.58962K562RBM15
chr181232506412325070+3'-UTR,CDS,intron-Distal,intron-Proximal3.205897.11210K562YBX3
chr181232507012325084+3'-UTR,CDS,intron-Distal3.016857.54748K562YBX3
chr181232493612324990+3'-UTR,CDS,intron-Distal,intron-Proximal4.287393.48187K562RBM15
chr181232637712326435+3'-UTR,intron-Distal3.261506.15304K562YBX3
chr181232571712325729+3'-UTR,CDS,intron-Distal4.038303.65750K562YBX3
chr181232627512326345+3'-UTR,intron-Distal3.353385.66840K562ZNF622
chr181232508412325101+3'-UTR,CDS,intron-Distal,intron-Proximal3.254258.04936K562YBX3
chr181232626212326315+3'-UTR,intron-Distal3.788748.69423K562PUM2
chr181232643012326515+3'-UTR,intron-Distal4.244675.47880HepG2SUB1
chr181232603012326052+3'-UTR,CDS,intron-Distal3.480564.31744K562YBX3
chr181231094112310943+5'-UTR,CDS,intron-Distal,intron-Proximal3.079115.56979K562YBX3
chr181231095112310976+5'-UTR,CDS,intron-Distal3.453346.61971K562YBX3
chr181231089412310973+5'-UTR,CDS,intron-Distal,intron-Proximal3.155945.42785K562SF3B4
chr181231094812311027+5'-UTR,CDS,intron-Distal3.804684.49723K562ZNF800
chr181230869112308806+CDS,intron-Distal,intron-Proximal4.080954.49723K562ZNF800
chr181230877512308795+CDS,intron-Distal,intron-Proximal3.225726.15304K562YBX3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TUBB6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TUBB6 is not available on ENCORE database.

  • 144 RBPs can affect the levels of TUBB6.  








The Knockdown/knockout RNA-Seq assay for TUBB6 is not available on ENCORE database.





144 RBPs can affect the gene expression of TUBB6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TUBB6ENSG00000176014.8440.28580265.175600.731405.610004.13210HepG2AATF
TUBB6ENSG00000176014.8261.27470500.57010-0.938007.494006.04890HepG2ABCF1
TUBB6ENSG00000176014.81924.55490388.680402.30780144.14010141.53310HepG2ACO1
TUBB6ENSG00000176014.8170.07180323.39690-0.927206.762605.29130HepG2ADAR
TUBB6ENSG00000176014.81214.82830140.406803.1130071.9461069.83810HepG2AKAP1
TUBB6ENSG00000176014.81126.55910320.833901.8119034.3153031.24360HepG2AKAP8
TUBB6ENSG00000176014.8595.16120390.499000.607906.737905.59620HepG2AKAP8L
TUBB6ENSG00000176014.8279.09440116.159701.264509.053707.68560HepG2ASCC1
TUBB6ENSG00000176014.8775.01540434.203600.8358013.9426012.61140HepG2AUH
TUBB6ENSG00000176014.8512.31970300.927600.767504.867603.61980HepG2BCCIP
TUBB6ENSG00000176014.8640.54310381.847900.746204.584903.62160HepG2CALR
TUBB6ENSG00000176014.81206.37650846.639500.510803.333802.25590HepG2CCAR1
TUBB6ENSG00000176014.8809.14190412.137300.9732012.9848010.80750HepG2CPSF7
TUBB6ENSG00000176014.8317.50650185.872900.772404.966003.58150HepG2CSTF2
TUBB6ENSG00000176014.81467.06560486.109101.5935045.8561043.89720HepG2CELF1
TUBB6ENSG00000176014.8384.96500522.69250-0.441203.994603.12990HepG2DAZAP1
TUBB6ENSG00000176014.8180.10810359.46950-0.9970012.1332010.64160HepG2DDX19B
TUBB6ENSG00000176014.8130.31570286.29350-1.135509.063107.44230HepG2DDX24
TUBB6ENSG00000176014.8402.13730134.466601.5803015.7981014.42960HepG2DDX3X
TUBB6ENSG00000176014.81618.61790295.877202.4516057.1275054.42420HepG2DDX55
TUBB6ENSG00000176014.81037.46050508.138901.029706.417304.95720HepG2DDX59
TUBB6ENSG00000176014.8273.33200431.00380-0.657004.501403.22650HepG2DDX5
TUBB6ENSG00000176014.81077.89740115.586003.2211030.1855028.47450HepG2DDX6
TUBB6ENSG00000176014.8140.95340314.08930-1.156009.979708.25010HepG2DHX30
TUBB6ENSG00000176014.880.24950371.85950-2.2122034.2516032.56180HepG2DKC1
TUBB6ENSG00000176014.8523.96610325.656400.686007.112806.02790HepG2DNAJC21
TUBB6ENSG00000176014.8387.86540269.401600.525702.485001.44270HepG2AGO1
TUBB6ENSG00000176014.8367.66490111.039801.7272017.5456016.14290HepG2EIF2S1
TUBB6ENSG00000176014.8588.87090379.655300.633205.449003.84460HepG2EIF2S2
TUBB6ENSG00000176014.8462.29910261.068400.824305.795304.52140HepG2EIF3D
TUBB6ENSG00000176014.8166.45610276.26370-0.730904.606703.25470HepG2EIF3G
TUBB6ENSG00000176014.8435.66790119.511701.8660015.0850013.55750HepG2EIF4B
TUBB6ENSG00000176014.8279.97980493.97320-0.819107.022205.74960HepG2EIF4G2
TUBB6ENSG00000176014.8169.24240433.56070-1.3571015.2395013.01100HepG2ESF1
TUBB6ENSG00000176014.8347.44700498.50710-0.520804.202003.48840HepG2ETF1
TUBB6ENSG00000176014.81112.57630379.802101.5505036.8954034.25250HepG2EWSR1
TUBB6ENSG00000176014.8344.85850233.400600.563103.552802.21160HepG2FAM120A
TUBB6ENSG00000176014.8426.69820278.780700.614004.357502.96870HepG2FASTKD2
TUBB6ENSG00000176014.81676.76360505.436201.7300019.8450018.11980HepG2FIP1L1
TUBB6ENSG00000176014.8217.19720448.23400-1.045204.207702.95620HepG2FTO
TUBB6ENSG00000176014.8603.87340123.885302.2851037.3148035.15140HepG2FXR1
TUBB6ENSG00000176014.8508.19060114.863402.1454017.8275016.21390HepG2G3BP1
TUBB6ENSG00000176014.8358.67890232.437100.625803.117902.16280HepG2GEMIN5
TUBB6ENSG00000176014.8428.41280256.060400.742404.750603.41550HepG2GNB2L1
TUBB6ENSG00000176014.8281.07930507.25680-0.851706.417305.47010HepG2GPKOW
TUBB6ENSG00000176014.8544.99860270.515101.010407.251804.89780HepG2GTF2F1
TUBB6ENSG00000176014.8140.41230328.77600-1.2274010.164909.04290HepG2HNRNPA1
TUBB6ENSG00000176014.8757.12060480.366500.656308.673607.19480HepG2HNRNPA2B1
TUBB6ENSG00000176014.8242.55320365.69380-0.592303.356202.59880HepG2HNRNPC
TUBB6ENSG00000176014.8590.47660765.88580-0.375201.996701.38060HepG2HNRNPF
TUBB6ENSG00000176014.8281.43110116.445801.273005.924704.93290HepG2HNRNPK
TUBB6ENSG00000176014.8375.68660476.13470-0.341802.435101.79890HepG2HNRNPL
TUBB6ENSG00000176014.8182.96460484.08360-1.4037015.3737014.05550HepG2HNRNPLL
TUBB6ENSG00000176014.8601.00240348.675400.785407.980006.49450HepG2HNRNPM
TUBB6ENSG00000176014.8494.50300754.19120-0.609003.502102.69520HepG2IGF2BP1
TUBB6ENSG00000176014.8412.47430116.735401.8210020.6234018.97740HepG2IGF2BP2
TUBB6ENSG00000176014.8596.03610109.634702.442605.919904.50540HepG2IGF2BP3
TUBB6ENSG00000176014.8628.76820371.076600.7607012.2199010.80160HepG2ILF2
TUBB6ENSG00000176014.8458.00520306.822500.577902.777201.45430HepG2ILF3
TUBB6ENSG00000176014.8198.26790117.454700.755202.784201.77890HepG2KHSRP
TUBB6ENSG00000176014.8379.30660226.627000.742904.891902.75120HepG2CCAR2
TUBB6ENSG00000176014.8624.30780250.931901.3149017.5382014.97230HepG2LARP7
TUBB6ENSG00000176014.8203.27590123.929000.713802.175901.59220HepG2MAGOH
TUBB6ENSG00000176014.81190.21330124.604603.2557036.1020034.03400HepG2MATR3
TUBB6ENSG00000176014.8627.78160273.206501.200208.917507.14550HepG2METAP2
TUBB6ENSG00000176014.8782.62130408.981400.9362011.9674010.40360HepG2MSI2
TUBB6ENSG00000176014.8434.70530127.525001.7692019.6095018.02200HepG2NCBP2
TUBB6ENSG00000176014.8500.11690331.067800.595003.194501.65640HepG2NKRF
TUBB6ENSG00000176014.8998.99890518.300500.9466017.3168015.50990HepG2NOL12
TUBB6ENSG00000176014.884.79720429.22570-2.3396030.0899028.05540HepG2NSUN2
TUBB6ENSG00000176014.8413.60930254.970400.697804.001101.59420HepG2NUSAP1
TUBB6ENSG00000176014.8947.15370287.675601.7191018.5308016.21830HepG2PABPC1
TUBB6ENSG00000176014.8336.57960113.502001.568108.392007.14990HepG2PABPC4
TUBB6ENSG00000176014.8624.84510359.592700.7970010.766209.27810HepG2PARN
TUBB6ENSG00000176014.8254.98710126.612801.009903.632902.95750HepG2PCBP1
TUBB6ENSG00000176014.8227.66940324.01530-0.509103.189902.40360HepG2PPIL4
TUBB6ENSG00000176014.844.04790274.55280-2.6399035.2345033.12240HepG2PRPF4
TUBB6ENSG00000176014.8563.78800128.857502.1293046.2989044.64650HepG2PTBP1
TUBB6ENSG00000176014.8813.10560525.209300.6305010.189909.20170HepG2PUM1
TUBB6ENSG00000176014.8962.19020524.826800.874407.574506.48860HepG2PUM2
TUBB6ENSG00000176014.8251.93840395.89490-0.652005.927605.08680HepG2PUS1
TUBB6ENSG00000176014.848.09310139.50410-1.536404.512303.74180HepG2QKI
TUBB6ENSG00000176014.8826.75030262.095301.6573015.9702014.41710HepG2RAVER1
TUBB6ENSG00000176014.81328.24430555.164901.2584024.6447022.53630HepG2RBM15
TUBB6ENSG00000176014.81780.43240416.663102.0952037.3790035.89990HepG2RBM22
TUBB6ENSG00000176014.8471.26900302.595100.639103.738302.57580HepG2RBM27
TUBB6ENSG00000176014.8463.19750143.385901.691609.986209.07660HepG2NELFE
TUBB6ENSG00000176014.8282.42860133.581101.080106.293605.41680HepG2RECQL
TUBB6ENSG00000176014.855.08170257.54140-2.2252018.0337015.86950HepG2RPS10
TUBB6ENSG00000176014.8583.07800254.066801.1984015.5462014.25350HepG2RPS19
TUBB6ENSG00000176014.8447.51910279.052000.681304.168003.19460HepG2RPS2
TUBB6ENSG00000176014.8575.89670284.874001.015409.604407.61810HepG2RPS5
TUBB6ENSG00000176014.8400.90880225.765600.828305.178104.13540HepG2RRP9
TUBB6ENSG00000176014.8163.25140300.23930-0.879004.405802.46850HepG2SBDS
TUBB6ENSG00000176014.8411.11090254.939100.689304.423603.24620HepG2SERBP1
TUBB6ENSG00000176014.8250.69390479.15280-0.934608.401207.23460HepG2SF3B1
TUBB6ENSG00000176014.8458.73230134.113701.7741023.1647021.73510HepG2SF3B4
TUBB6ENSG00000176014.8268.68850474.39520-0.820209.703908.51510HepG2SLBP
TUBB6ENSG00000176014.8869.07280377.286601.2037031.3134029.53660HepG2SMN1
TUBB6ENSG00000176014.8731.06110267.484501.4504017.2953014.88680HepG2SMNDC1
TUBB6ENSG00000176014.8303.61430533.13950-0.812304.802603.75960HepG2SNRNP70
TUBB6ENSG00000176014.82236.66270470.611902.24860147.62580145.40740HepG2SRFBP1
TUBB6ENSG00000176014.8487.21420140.003501.7990030.7457029.54410HepG2SRSF1
TUBB6ENSG00000176014.8976.61760488.502600.9993021.8402020.31230HepG2SRSF5
TUBB6ENSG00000176014.8511.73470113.915602.1673012.0651011.05670HepG2SRSF9
TUBB6ENSG00000176014.8124.57130408.61330-1.7138026.5329025.30920HepG2SSB
TUBB6ENSG00000176014.8794.75170348.051601.1911014.6553012.13040HepG2SSRP1
TUBB6ENSG00000176014.8414.49160244.946800.758803.782002.37280HepG2SUB1
TUBB6ENSG00000176014.81388.44260555.564001.3213048.6798046.64870HepG2SUCLG1
TUBB6ENSG00000176014.8787.59200352.416501.1601011.884809.14270HepG2SUGP2
TUBB6ENSG00000176014.8464.01930341.221300.443402.905301.94160HepG2SUPT6H
TUBB6ENSG00000176014.8649.34420294.536801.1404010.766109.57620HepG2SUPV3L1
TUBB6ENSG00000176014.8157.33020471.80600-1.5844019.5234017.92070HepG2TARDBP
TUBB6ENSG00000176014.8196.57550341.86760-0.798403.025301.91130HepG2TBRG4
TUBB6ENSG00000176014.8409.88290197.415101.053908.867407.28700HepG2TFIP11
TUBB6ENSG00000176014.8183.24500115.623300.664202.701901.87490HepG2TIA1
TUBB6ENSG00000176014.8739.63800353.023901.0670016.9905015.94320HepG2TIAL1
TUBB6ENSG00000176014.8663.55930356.144600.8977014.5761013.42520HepG2TRIM56
TUBB6ENSG00000176014.8806.55740310.049801.379205.048303.69070HepG2U2AF2
TUBB6ENSG00000176014.81337.87450511.624601.3867021.7232019.43460HepG2UBE2L3
TUBB6ENSG00000176014.8615.07510204.476101.5887017.6675016.20220HepG2UPF1
TUBB6ENSG00000176014.8431.11020197.416301.1267010.054309.02670HepG2UTP3
TUBB6ENSG00000176014.8679.44950288.280201.2368012.0449010.00630HepG2XRCC6
TUBB6ENSG00000176014.8157.14720289.93930-0.883605.054904.08320HepG2XRN2
TUBB6ENSG00000176014.8515.27080270.948500.9272012.9075011.63150HepG2ZC3H8
TUBB6ENSG00000176014.8718.10540224.887001.6749020.3739019.22750HepG2ZNF622
TUBB6ENSG00000176014.82644.795502179.599100.279002.353901.74990K562AKAP8L
TUBB6ENSG00000176014.84171.140203433.435500.280702.740001.50550K562APOBEC3C
TUBB6ENSG00000176014.82202.512603248.00110-0.560407.314806.43410K562AQR
TUBB6ENSG00000176014.81857.514101434.695100.372503.247402.08780K562CCAR1
TUBB6ENSG00000176014.82018.150001396.108000.531506.242204.36220K562CIRBP
TUBB6ENSG00000176014.81895.729002481.78160-0.388604.862903.94570K562EIF2S2
TUBB6ENSG00000176014.81325.65530955.104600.472905.637104.51610K562EIF3G
TUBB6ENSG00000176014.83318.464403891.13830-0.229702.835901.88620K562EIF4G2
TUBB6ENSG00000176014.81049.441601653.63020-0.656007.197905.24360K562FKBP4
TUBB6ENSG00000176014.81369.551301767.48070-0.368002.658401.76290K562FTO
TUBB6ENSG00000176014.82266.140501613.909200.489608.746107.74290K562FXR1
TUBB6ENSG00000176014.8632.88800873.62620-0.465102.673701.98160K562G3BP2
TUBB6ENSG00000176014.81404.396901903.10020-0.438405.070604.28460K562HNRNPC
TUBB6ENSG00000176014.82571.615003119.32670-0.278602.598501.57720K562HNRNPL
TUBB6ENSG00000176014.82437.528101879.016900.375302.762201.83290K562HNRNPM
TUBB6ENSG00000176014.81725.540102560.87750-0.569604.681603.51270K562HNRNPU
TUBB6ENSG00000176014.82330.594403097.40690-0.410404.287803.30350K562HSPD1
TUBB6ENSG00000176014.81712.331101369.016400.322702.838101.98660K562MAGOH
TUBB6ENSG00000176014.81916.076401366.208300.487906.288504.81540K562MATR3
TUBB6ENSG00000176014.82101.356802743.20950-0.384507.530806.25400K562MTPAP
TUBB6ENSG00000176014.82326.375503041.84960-0.386903.076402.19830K562PCBP3
TUBB6ENSG00000176014.81839.185702333.12830-0.343203.759002.81990K562POLR2G
TUBB6ENSG00000176014.82274.934101330.100400.7742015.3612013.86190K562PTBP1
TUBB6ENSG00000176014.8739.12170977.62670-0.403503.921601.77110K562QKI
TUBB6ENSG00000176014.81878.062701275.296600.558306.765005.38260K562RBM22
TUBB6ENSG00000176014.8616.42500828.68500-0.426903.342901.86370K562RBM25
TUBB6ENSG00000176014.81598.789001243.255700.362802.749901.37820K562RBM34
TUBB6ENSG00000176014.82039.397401557.436600.388904.370603.12360K562RCC2
TUBB6ENSG00000176014.8647.27780940.60330-0.539208.074605.51900K562RPS10
TUBB6ENSG00000176014.82605.803703081.22410-0.241804.109102.99150K562SRPK2
TUBB6ENSG00000176014.81679.600801303.964600.365103.622102.82040K562SRSF1
TUBB6ENSG00000176014.81270.22900871.421200.543506.026804.36460K562SRSF4
TUBB6ENSG00000176014.81524.654401231.552700.307902.319901.37210K562SRSF5
TUBB6ENSG00000176014.82157.339902997.52050-0.474505.336003.41330K562SSRP1
TUBB6ENSG00000176014.82128.086102741.66280-0.365502.972401.66910K562STAU1
TUBB6ENSG00000176014.8483.34470857.57100-0.827204.739802.63840K562TAF15
TUBB6ENSG00000176014.8643.91850910.66810-0.500004.226802.21980K562TBRG4
TUBB6ENSG00000176014.81775.430201272.962600.479906.007004.73050K562TIA1
TUBB6ENSG00000176014.81584.602801249.271000.342902.757301.66800K562TRA2A
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TUBB6 is not available on ENCORE database.





4 RBPs can affect the splicing of TUBB6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETUBB6ENSG00000176014.8chr18+1230868512308794123082421230834812329144123298250.062000.001450.07536includedHepG2AKAP1
SETUBB6ENSG00000176014.8chr18+1231094112311052123086851230879412325065123250990.196000.002270.08208includedHepG2SFPQ
SETUBB6ENSG00000176014.8chr18+123109411231105212308685123087941232506512325099-0.193000.000370.01013excludedK562U2AF1
SETUBB6ENSG00000176014.8chr18+123109411231105212308685123087941232506512325099-0.107000.004860.07089excludedK562U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TUBB6 is not avaliable on ENCORE database.