SERPINB6

General Information

Gene Name       : SERPINB6
Gene ID             : ENSG00000124570.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SERPINB6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SERPINB6ENSG00000124570.190.620.460.54ENCSR000AEF
HepG2SERPINB6ENSG00000124570.1926.1631.6028.88ENCSR985KAT
K562SERPINB6ENSG00000124570.19117.21118.29117.75ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SERPINB6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SERPINB6 RNA is bound by 31 proteins.  







eCLIP assay for SERPINB6 is not avaliable on ENCORE database.





31 proteins are bound to SERPINB6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr629595632959600-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.0669413.03281K562SF3B4
chr629484632948540-3'-UTR,CDS,intron-Distal3.115453.69308K562DDX6
chr629484322948527-3'-UTR,intron-Distal3.141555.91053HepG2LARP4
chr629595532959657-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.192914.32536HepG2SF3B4
chr629484772948504-3'-UTR,intron-Distal5.8565722.79979K562PABPC4
chr629484222948477-3'-UTR,intron-Distal4.9474017.28377K562PABPC4
chr629484442948557-3'-UTR,CDS,intron-Distal4.581989.43046K562PCBP1
chr629485042948548-3'-UTR,CDS,intron-Distal5.4270010.44987K562PABPC4
chr629714242971512-5'-UTR,intron-Distal,intron-Proximal3.833885.97131K562DDX3X
chr629601822960257-5'-UTR,intron-Distal4.996138.12044K562HNRNPM
chr629612382961324-5'-UTR,intron-Distal4.479675.31505K562HNRNPM
chr629612172961328-5'-UTR,intron-Distal4.117033.72005K562MATR3
chr629607942960892-5'-UTR,intron-Distal4.342904.47904K562HNRNPK
chr629714912971584-5'-UTR,intron-Distal,intron-Proximal3.376006.73713HepG2CSTF2T
chr629596822959786-5'-UTR,intron-Distal3.619235.45345K562HNRNPL
chr629596002959623-5'-UTR,intron-Distal,intron-Proximal5.481417.91936K562SF3B4
chr629533292953419-CDS,intron-Distal3.533803.91115K562LIN28B
chr629548532954942-CDS,intron-Distal3.9762910.40970K562LIN28B
chr629548992954919-CDS,intron-Distal3.122595.92071K562YBX3
chr629485682948592-CDS,intron-Distal4.104176.57313K562PABPC4
chr629491472949253-CDS,intron-Distal,intron-Proximal3.709016.02304HepG2GRWD1
chr629487582948851-CDS,intron-Distal3.772416.23998K562PUM1
chr629594012959501-CDS,intron-Distal,intron-Proximal3.616743.86355HepG2PPIG
chr629488632948904-CDS,intron-Distal3.463873.33377K562PUM1
chr629488062948929-CDS,intron-Distal3.414006.87883K562ZNF800
chr629487942948838-CDS,intron-Distal3.176973.08948K562DDX55
chr629488532948934-CDS,intron-Distal4.234814.72880HepG2GRWD1
chr629558092955894-CDS,intron-Distal3.3884714.54182K562YBX3
chr629491502949233-CDS,intron-Distal3.514587.33476K562PABPC4
chr629491492949299-CDS,intron-Distal4.3053512.52201HepG2BCLAF1
chr629593842959401-intron-Distal,intron-Proximal4.035845.26367K562AQR
chr629664622966533-intron-Distal3.993094.02219K562KHDRBS1
chr629556812955754-intron-Distal,intron-Proximal4.560864.09264K562AQR
chr629638362963951-intron-Distal3.577287.71901K562RBFOX2
chr629653412965438-intron-Distal3.282634.43137K562KHDRBS1
chr629697782969933-intron-Distal3.184203.70419K562KHDRBS1
chr629716112971674-intron-Distal,intron-Proximal4.140156.08301HepG2EFTUD2
chr629700162970041-intron-Distal3.008238.93911K562HNRNPL
chr629567172956739-intron-Distal5.027316.44303K562AQR
chr629674142967463-intron-Distal4.164773.59909K562EXOSC5
chr629616272961671-intron-Distal,intron-Proximal4.579155.68226HepG2HNRNPM
chr629638512963953-intron-Distal3.629468.37391HepG2RBFOX2
chr629700022970059-intron-Distal3.289957.63703K562AGGF1
chr629638632963956-intron-Distal3.990819.08614K562EXOSC5
chr629716072971668-intron-Distal,intron-Proximal3.260133.06644K562GTF2F1
chr629710722971169-intron-Distal3.303783.36034K562SRSF1
chr629715922971669-intron-Distal,intron-Proximal3.345546.62443K562CSTF2T
chr629566752956717-intron-Distal5.284597.23718K562AQR
chr629715852971667-intron-Distal,intron-Proximal3.501894.34865K562NONO
chr629673502967462-intron-Distal4.043578.65817HepG2HNRNPM
chr629647752964857-intron-Distal3.206634.09325K562KHDRBS1
chr629638482963968-intron-Distal3.500347.51388K562HNRNPM
chr629699782970068-intron-Distal3.3390013.22532HepG2HNRNPL
chr629715952971669-intron-Distal,intron-Proximal3.249373.40641HepG2GTF2F1
chr629636882963741-intron-Distal3.981523.28572K562HNRNPM
chr629636822963812-intron-Distal3.620705.22800K562RBFOX2
chr629673612967449-intron-Distal3.100716.35387K562HNRNPM
chr629716052971675-intron-Distal,intron-Proximal3.341646.58651HepG2CSTF2T
chr629716192971665-intron-Distal,intron-Proximal5.369253.62726K562DROSHA
chr629659552966029-intron-Distal3.257164.30020K562KHDRBS1
chr629716162971677-intron-Distal,intron-Proximal4.440484.57620HepG2PRPF4
chr629637662963822-intron-Distal4.394493.59909K562EXOSC5
chr629593602959384-intron-Distal,intron-Proximal5.206366.83960K562AQR
chr629692682969351-intron-Distal5.7275711.75303HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SERPINB6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SERPINB6 is not available on ENCORE database.

  • 110 RBPs can affect the levels of SERPINB6.  








The Knockdown/knockout RNA-Seq assay for SERPINB6 is not available on ENCORE database.





110 RBPs can affect the gene expression of SERPINB6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SERPINB6ENSG00000124570.131133.45240899.965400.332702.485001.46630HepG2AATF
SERPINB6ENSG00000124570.131293.892301690.50230-0.385702.720601.78560HepG2ABCF1
SERPINB6ENSG00000124570.132116.061801502.522200.493906.779305.91310HepG2ACO1
SERPINB6ENSG00000124570.13704.001201071.17510-0.605505.970404.58010HepG2ADAR
SERPINB6ENSG00000124570.133156.111801876.176400.750308.670207.78790HepG2AKAP1
SERPINB6ENSG00000124570.132239.039601766.598700.341802.319301.36170HepG2AKAP8
SERPINB6ENSG00000124570.131922.683701552.394700.308502.080701.39580HepG2ASCC1
SERPINB6ENSG00000124570.131452.096401004.659800.531304.186903.03550HepG2BCCIP
SERPINB6ENSG00000124570.13764.590301474.87660-0.9478013.5868012.02100HepG2CIRBP
SERPINB6ENSG00000124570.131177.078501502.09290-0.351805.487304.61050HepG2CKAP4
SERPINB6ENSG00000124570.131766.725101392.138300.343703.126301.95150HepG2CPSF7
SERPINB6ENSG00000124570.13815.802001098.45920-0.429204.787103.45130HepG2YBX3
SERPINB6ENSG00000124570.13404.17980620.60420-0.618704.839903.46810HepG2CSTF2
SERPINB6ENSG00000124570.132027.424001710.664800.245002.813702.16590HepG2CELF1
SERPINB6ENSG00000124570.131484.292101100.024500.432104.266702.84920HepG2DDX1
SERPINB6ENSG00000124570.13783.92190992.35190-0.340102.400701.76370HepG2DDX21
SERPINB6ENSG00000124570.132661.260401797.270000.566205.932205.04900HepG2DDX3X
SERPINB6ENSG00000124570.132041.06300987.777301.0470014.8154013.21300HepG2DDX55
SERPINB6ENSG00000124570.13912.359601298.91070-0.509602.306601.41660HepG2DDX59
SERPINB6ENSG00000124570.132364.089101543.810000.614705.889905.01730HepG2DDX6
SERPINB6ENSG00000124570.13843.541401437.48000-0.7690017.1117015.74750HepG2DKC1
SERPINB6ENSG00000124570.131396.06260914.218500.610704.895403.41720HepG2AGO1
SERPINB6ENSG00000124570.132225.993601484.183500.584706.115505.25290HepG2EIF2S1
SERPINB6ENSG00000124570.131183.89410857.273500.465603.716202.67750HepG2EIF3D
SERPINB6ENSG00000124570.13580.72620937.43850-0.690908.799207.09030HepG2EIF3G
SERPINB6ENSG00000124570.131173.667401640.23660-0.482903.550802.82900HepG2EIF4A3
SERPINB6ENSG00000124570.131203.345401596.92530-0.408202.244701.62150HepG2EIF4B
SERPINB6ENSG00000124570.13970.165601464.38480-0.594006.650005.04490HepG2ESF1
SERPINB6ENSG00000124570.13987.25310766.158500.365703.302902.01100HepG2FAM120A
SERPINB6ENSG00000124570.132574.828001706.995300.592905.869704.79020HepG2FIP1L1
SERPINB6ENSG00000124570.13669.871001124.70530-0.7476010.374108.90040HepG2FUBP3
SERPINB6ENSG00000124570.13868.030901629.66840-0.9088013.0250011.10450HepG2G3BP2
SERPINB6ENSG00000124570.132378.439901690.379900.492608.945307.44670HepG2HNRNPA2B1
SERPINB6ENSG00000124570.13637.408701211.27100-0.9262013.9626012.52110HepG2HNRNPC
SERPINB6ENSG00000124570.131332.572801626.80370-0.287803.270902.49590HepG2HNRNPF
SERPINB6ENSG00000124570.13792.401301554.32420-0.9720015.6226014.10180HepG2HNRNPK
SERPINB6ENSG00000124570.131592.610901177.735900.435304.771203.56200HepG2HNRNPM
SERPINB6ENSG00000124570.131217.824001601.94070-0.395504.333603.44450HepG2IGF2BP1
SERPINB6ENSG00000124570.131029.142901560.46090-0.600506.068005.10560HepG2IGF2BP2
SERPINB6ENSG00000124570.131173.010301569.51530-0.420102.492701.55000HepG2KHSRP
SERPINB6ENSG00000124570.131310.45390957.850000.452104.510203.05780HepG2LARP7
SERPINB6ENSG00000124570.131123.919801655.38790-0.558605.264504.36570HepG2MAGOH
SERPINB6ENSG00000124570.131107.430201664.67230-0.588005.179004.34050HepG2MATR3
SERPINB6ENSG00000124570.131765.230901381.502400.353503.399802.50550HepG2MSI2
SERPINB6ENSG00000124570.131178.286801703.90050-0.532204.636303.82840HepG2NCBP2
SERPINB6ENSG00000124570.131293.660901823.00030-0.494903.124301.60410HepG2NKRF
SERPINB6ENSG00000124570.13761.427001097.19440-0.527004.545603.59340HepG2NSUN2
SERPINB6ENSG00000124570.131258.149701512.39450-0.265503.003102.37440HepG2PCBP1
SERPINB6ENSG00000124570.13821.594501073.21960-0.385404.140003.25510HepG2PPIL4
SERPINB6ENSG00000124570.13635.665501121.76470-0.8194016.7881015.14740HepG2PRPF4
SERPINB6ENSG00000124570.131385.142601741.00550-0.329902.781402.18330HepG2PUF60
SERPINB6ENSG00000124570.131472.823101846.82310-0.326503.205802.48330HepG2PUM2
SERPINB6ENSG00000124570.131071.822901530.40130-0.513809.961108.91490HepG2PUS1
SERPINB6ENSG00000124570.131015.432501666.71740-0.7149013.4934012.26530HepG2QKI
SERPINB6ENSG00000124570.131445.967801064.847300.441301.945601.34420HepG2RAVER1
SERPINB6ENSG00000124570.132607.281001923.711200.438605.991604.78930HepG2RBM15
SERPINB6ENSG00000124570.132322.478501833.395600.341004.615903.99140HepG2RBM22
SERPINB6ENSG00000124570.13924.179701512.62910-0.7108010.998409.71430HepG2RBM25
SERPINB6ENSG00000124570.131162.031001712.65950-0.5596010.596509.66510HepG2NELFE
SERPINB6ENSG00000124570.13760.988901595.06450-1.0677032.7202031.03880HepG2RECQL
SERPINB6ENSG00000124570.131366.522001752.41500-0.358803.079902.36540HepG2RPLP0
SERPINB6ENSG00000124570.13657.679501045.80090-0.669204.421103.23320HepG2RPS10
SERPINB6ENSG00000124570.131226.29160837.221300.550505.330104.03480HepG2SERBP1
SERPINB6ENSG00000124570.13829.548201358.58090-0.711705.100804.16580HepG2SF3A3
SERPINB6ENSG00000124570.13560.249901224.84410-1.1285018.8519017.18540HepG2SF3B1
SERPINB6ENSG00000124570.13936.646201602.23460-0.7745018.5354017.21830HepG2SF3B4
SERPINB6ENSG00000124570.131224.738301669.45540-0.446908.262407.14850HepG2SLBP
SERPINB6ENSG00000124570.131547.421401249.657800.308204.668903.86980HepG2SMN1
SERPINB6ENSG00000124570.132429.634202070.755600.230502.953602.44130HepG2SRFBP1
SERPINB6ENSG00000124570.13935.303601672.36420-0.8384022.5375021.46750HepG2SRSF1
SERPINB6ENSG00000124570.131347.812001719.04920-0.351004.638203.86330HepG2SRSF5
SERPINB6ENSG00000124570.131237.497301598.26910-0.369104.932704.04470HepG2SRSF7
SERPINB6ENSG00000124570.131856.200701360.538500.448108.284107.42070HepG2SRSF9
SERPINB6ENSG00000124570.131261.903401797.91090-0.5107010.199709.33440HepG2SSB
SERPINB6ENSG00000124570.131461.54900995.094900.554503.442002.09170HepG2SUB1
SERPINB6ENSG00000124570.132435.930701954.981200.317205.931305.08380HepG2SUCLG1
SERPINB6ENSG00000124570.131449.921601940.56660-0.420502.574201.30110HepG2SUGP2
SERPINB6ENSG00000124570.131634.106201152.621000.503506.212204.84010HepG2SUPT6H
SERPINB6ENSG00000124570.131045.135601503.12550-0.524308.121507.24240HepG2TAF15
SERPINB6ENSG00000124570.13929.817201206.00510-0.375202.780802.05490HepG2TARDBP
SERPINB6ENSG00000124570.131253.241001882.40950-0.586902.455701.44700HepG2TBRG4
SERPINB6ENSG00000124570.13907.80110659.107600.461802.916601.89490HepG2TFIP11
SERPINB6ENSG00000124570.13820.586801169.28000-0.510906.207305.51160HepG2TIAL1
SERPINB6ENSG00000124570.131501.143001179.642600.347604.754004.05520HepG2TRIM56
SERPINB6ENSG00000124570.131529.304001204.853600.343904.858803.97420HepG2UPF1
SERPINB6ENSG00000124570.13769.706001107.02580-0.524308.691307.61120HepG2ZC3H8
SERPINB6ENSG00000124570.131927.360101325.108300.5404014.1427013.14690HepG2ZNF622
SERPINB6ENSG00000124570.132172.625904695.90080-1.1120027.4425025.79370K562AQR
SERPINB6ENSG00000124570.136365.057005267.691400.272903.111901.85000K562CCDC124
SERPINB6ENSG00000124570.135838.116606855.81860-0.231802.498801.57260K562CELF1
SERPINB6ENSG00000124570.134828.150004118.445600.229303.350702.64400K562DDX47
SERPINB6ENSG00000124570.134212.168204935.59690-0.228702.877101.98270K562DKC1
SERPINB6ENSG00000124570.131490.288801995.63500-0.421304.025002.90730K562EFTUD2
SERPINB6ENSG00000124570.135480.850803468.757900.6599019.8746018.20800K562EIF2S2
SERPINB6ENSG00000124570.131992.508502432.63880-0.287903.511502.62110K562EIF3G
SERPINB6ENSG00000124570.131503.592302348.80930-0.643509.413407.89270K562EIF4A3
SERPINB6ENSG00000124570.134178.887102969.313300.492906.421205.09030K562FIP1L1
SERPINB6ENSG00000124570.132421.168802969.73500-0.294602.752001.32540K562G3BP1
SERPINB6ENSG00000124570.131513.429702607.22150-0.7847015.5574014.22470K562HNRNPC
SERPINB6ENSG00000124570.131942.203203102.38100-0.675708.968906.70360K562HNRNPK
SERPINB6ENSG00000124570.132555.443703721.95860-0.542508.445406.52590K562HNRNPL
SERPINB6ENSG00000124570.133076.394302442.478700.332802.413701.54780K562HNRNPM
SERPINB6ENSG00000124570.135930.342804025.511500.558807.998806.66160K562HSPD1
SERPINB6ENSG00000124570.132460.548103106.18380-0.336202.207201.32120K562IGF2BP2
SERPINB6ENSG00000124570.132278.282703264.52220-0.518907.425306.02090K562MAGOH
SERPINB6ENSG00000124570.138049.730505943.286100.437605.738404.11510K562MSI2
SERPINB6ENSG00000124570.132501.611203061.68450-0.291504.624303.60030K562MTPAP
SERPINB6ENSG00000124570.133052.737303401.57490-0.156101.947601.30840K562NSUN2
SERPINB6ENSG00000124570.131992.348902904.62460-0.543907.457005.81920K562PCBP2
SERPINB6ENSG00000124570.134121.546103185.605500.371503.009902.14250K562PCBP3
SERPINB6ENSG00000124570.133293.140302443.492600.430406.247705.04880K562POLR2G
SERPINB6ENSG00000124570.134084.341803371.012000.276802.262301.52190K562PPIG
SERPINB6ENSG00000124570.131582.633001941.99190-0.295202.204901.53150K562PRPF8
SERPINB6ENSG00000124570.131842.332402337.74830-0.343603.144002.17100K562PSIP1
SERPINB6ENSG00000124570.133756.334003171.684400.244002.277501.66740K562PTBP1
SERPINB6ENSG00000124570.135761.512804548.765400.340903.539502.93700K562PUS1
SERPINB6ENSG00000124570.135154.689004431.929300.217902.426301.86450K562RBM15
SERPINB6ENSG00000124570.133127.719704383.49180-0.487007.352004.81890K562RBM17
SERPINB6ENSG00000124570.131943.988503041.29130-0.645709.684707.96090K562RBM22
SERPINB6ENSG00000124570.131987.122302395.77370-0.269804.157102.22670K562RPS10
SERPINB6ENSG00000124570.132234.747003034.97490-0.441603.808301.66050K562SAFB2
SERPINB6ENSG00000124570.131452.520302059.15050-0.503504.365003.12590K562SF3B1
SERPINB6ENSG00000124570.131631.998702375.06960-0.541308.804507.23090K562SF3B4
SERPINB6ENSG00000124570.132866.717003439.17670-0.262704.006802.90210K562SRPK2
SERPINB6ENSG00000124570.132102.944203109.30310-0.564209.390608.09850K562SRSF1
SERPINB6ENSG00000124570.131439.809501879.79580-0.384702.898201.85590K562SUPV3L1
SERPINB6ENSG00000124570.134390.396703792.410900.211102.772201.50150K562TROVE2
SERPINB6ENSG00000124570.132701.274301989.768500.440904.096802.83250K562UCHL5
SERPINB6ENSG00000124570.132510.024303606.78040-0.5230013.7187012.26520K562UPF1
SERPINB6ENSG00000124570.132434.523903037.14790-0.319103.296401.45100K562UPF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SERPINB6 is not available on ENCORE database.





6 RBPs can affect the splicing of SERPINB6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESERPINB6ENSG00000124570.13chr6-2969012296914729594012959576297172429718190.405000.004830.07387includedK562SRSF1
SESERPINB6ENSG00000124570.13chr6-2969012296914729594012959576297176629720900.179000.000060.00275includedHepG2HNRNPK
SESERPINB6ENSG00000124570.13chr6-2969012296914729594012959576297135029714400.327000.000300.09381includedK562KHSRP
SESERPINB6ENSG00000124570.13chr6-2961203296133029594012959576297176629720900.051000.002020.07014includedHepG2MATR3
SESERPINB6ENSG00000124570.13chr6-2969012296914729594012959576297148129715390.130000.000020.00135includedK562TARDBP
SESERPINB6ENSG00000124570.13chr6-2966633296682429594012959576297148129715390.139000.001220.04736includedK562SF3B1
SESERPINB6ENSG00000124570.13chr6-2969012296914729594012959576297176629720900.155000.000010.00100includedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SERPINB6 is not avaliable on ENCORE database.