PRPF4B

General Information

Gene Name : PRPF4B
Gene ID : ENSG00000112739.16
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: PRPF4B)

Not Available

Antibody Validation

Cell Signaling Technology: 8577S

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	PRPF4B	ENSG00000112739.16	54.86	50.71	52.78	ENCSR000AEF
HepG2	PRPF4B	ENSG00000112739.16	43.93	64.64	54.28	ENCSR985KAT
K562	PRPF4B	ENSG00000112739.16	53.35	62.27	57.81	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
PRPF4B		8577S	1			Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
PRPF4B	K562	CRISPR	BGKcLV42-71,BGKcLV42-72	BGKcLV42-1,BGKcLV42-2	0.0,0.0	NotSatisfied	ENCORE2
PRPF4B	K562	CRISPR	BGKcLV44-47,BGKcLV44-48	BGKcLV44-1,BGKcLV44-2		NotSatisfied	ENCORE2
PRPF4B	HepG2	CRISPR	BGHcLV45-51,BGHcLV45-52	BGHcLV45-1,BGHcLV45-2	39.5,28.4	NotSatisfied	ENCORE2
PRPF4B	HepG2	CRISPR	BGHcLV47-49,BGHcLV47-50	BGHcLV47-1,BGHcLV47-2		NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
PRPF4B	Product_ID: 8577S Lot_ID: 1 Source: Cell Signaling Technology Target Name: PRPF4B-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for PRPF4B is not avaliable on ENCORE database.

Proteins bound to RNA

PRPF4B RNA is bound by 40 proteins.

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eCLIP assay for PRPF4B is not avaliable on ENCORE database.

40 proteins are bound to PRPF4B RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr6	4061937	4061969	+	3'-UTR,intron-Proximal	8.25322	197.81449	K562	AQR
chr6	4062401	4062445	+	3'-UTR,intron-Proximal	7.46688	114.51692	K562	AQR
chr6	4061933	4061937	+	3'-UTR,intron-Proximal	8.03756	107.09339	K562	AQR
chr6	4061977	4061989	+	3'-UTR,intron-Proximal	6.86352	98.10357	K562	AQR
chr6	4061969	4061977	+	3'-UTR,intron-Proximal	7.66377	97.44602	K562	AQR
chr6	4061989	4061998	+	3'-UTR,intron-Proximal	7.21878	95.79572	K562	AQR
chr6	4061998	4062025	+	3'-UTR,intron-Proximal	7.12265	87.54969	K562	AQR
chr6	4065010	4065089	+	3'-UTR,intron-Proximal	4.83124	64.37869	HepG2	U2AF2
chr6	4032076	4032208	+	CDS	4.21831	41.14039	K562	ZNF622
chr6	4032120	4032263	+	CDS	3.73911	40.76787	K562	UCHL5
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 284 entries

eCLIP assay for PRPF4B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for PRPF4B is not available on ENCORE database.
106 RBPs can affect the levels of PRPF4B.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for PRPF4B is not available on ENCORE database.

106 RBPs can affect the gene expression of PRPF4B :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PRPF4B	ENSG00000112739.12	1558.45480	2762.63900	-0.82590	35.72560	33.63010	HepG2	DNAJC2
PRPF4B	ENSG00000112739.12	2002.86110	3109.38270	-0.63460	19.09670	17.61670	HepG2	HNRNPU
PRPF4B	ENSG00000112739.12	8426.89790	4987.94990	0.75650	13.92730	12.75430	K562	PUS1
PRPF4B	ENSG00000112739.12	4043.12670	6608.54460	-0.70890	14.83700	12.73860	K562	METAP2
PRPF4B	ENSG00000112739.12	3968.56720	5189.07300	-0.38690	12.38550	11.43620	HepG2	ZNF622
PRPF4B	ENSG00000112739.12	2433.27400	3724.98100	-0.61430	10.72400	9.61280	K562	HNRNPC
PRPF4B	ENSG00000112739.12	2225.63490	3048.34770	-0.45380	10.31610	9.33220	HepG2	TRIM56
PRPF4B	ENSG00000112739.12	4274.21080	3076.42560	0.47430	9.73680	8.78760	HepG2	TAF15
PRPF4B	ENSG00000112739.12	1914.76180	2787.34240	-0.54170	8.67980	7.48930	HepG2	DNAJC21
PRPF4B	ENSG00000112739.12	4203.94050	3264.53170	0.36480	7.74530	6.79080	HepG2	RECQL
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 128 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for PRPF4B is not available on ENCORE database.

48 RBPs can affect the splicing of PRPF4B :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	PRPF4B	ENSG00000112739.12	chr6	+	4062790	4062867	4061888	4062533	4063307	4063790	0.19900	0.00000	included	K562	SRSF1
SE	PRPF4B	ENSG00000112739.12	chr6	+	4056760	4056922	4056554	4056669	4057269	4057421	-0.07500	0.00016	excluded	K562	SRSF1
SE	PRPF4B	ENSG00000112739.12	chr6	+	4056760	4056922	4056554	4056669	4057269	4057421	-0.09900	0.00000	excluded	K562	PRPF8
SE	PRPF4B	ENSG00000112739.12	chr6	+	4056554	4056669	4052953	4053107	4057269	4057421	-0.21800	0.00000	excluded	K562	AKAP8L
SE	PRPF4B	ENSG00000112739.12	chr6	+	4056760	4056922	4056554	4056669	4057269	4057421	0.15800	0.00008	included	K562	HNRNPA1
SE	PRPF4B	ENSG00000112739.12	chr6	+	4056554	4056669	4052953	4053107	4057269	4057421	-0.37300	0.00000	excluded	K562	PUS1
SE	PRPF4B	ENSG00000112739.12	chr6	+	4062790	4062867	4062448	4062533	4063307	4063790	-0.24100	0.00000	excluded	K562	PUS1
SE	PRPF4B	ENSG00000112739.12	chr6	+	4056760	4056922	4056554	4056669	4057269	4057421	-0.09000	0.00005	excluded	K562	EFTUD2
SE	PRPF4B	ENSG00000112739.12	chr6	+	4056760	4056922	4056554	4056669	4057269	4057421	0.08000	0.00085	included	HepG2	HNRNPL
SE	PRPF4B	ENSG00000112739.12	chr6	+	4056760	4056922	4056554	4056669	4057269	4057421	0.13300	0.00007	included	K562	HNRNPL

Showing 1 to 10 of 111 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

PRPF4B

General Information

Functions

Localization

Domains (AlphaFold: PRPF4B)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for PRPF4B is not avaliable on ENCORE database.

40 proteins are bound to PRPF4B RNA:

eCLIP assay for PRPF4B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for PRPF4B is not available on ENCORE database.

106 RBPs can affect the gene expression of PRPF4B :

The Knockdown/knockout RNA-Seq assay for PRPF4B is not available on ENCORE database.

48 RBPs can affect the splicing of PRPF4B :

The Knockdown/knockout RNA-Seq assay for PRPF4B is not avaliable on ENCORE database.