PECR

General Information

Gene Name       : PECR
Gene ID             : ENSG00000115425.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PECR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PECRENSG00000115425.1319.0619.5919.32ENCSR000AEF
HepG2PECRENSG00000115425.1382.0875.7378.91ENCSR985KAT
K562PECRENSG00000115425.135.895.645.76ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PECR is not avaliable on ENCORE database.



Proteins bound to RNA
  • PECR RNA is bound by 22 proteins.  







eCLIP assay for PECR is not avaliable on ENCORE database.





22 proteins are bound to PECR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2216903809216903881-3'-UTR,intron-Distal,intron-Proximal3.459684.73068HepG2TIAL1
chr2216903185216903257-3'-UTR,intron-Distal3.372635.24326HepG2ZC3H11A
chr2216861066216861127-3'-UTR,5'-UTR,CDS,intron-Distal3.650096.02304HepG2GRWD1
chr2216861021216861066-3'-UTR,CDS,intron-Distal,intron-Proximal3.007523.41665HepG2GRWD1
chr2216861096216861179-3'-UTR,5'-UTR,CDS,intron-Distal3.305358.02162HepG2BCLAF1
chr2216860991216861059-3'-UTR,CDS,intron-Distal,intron-Proximal3.982525.13777HepG2PRPF8
chr2216861018216861061-3'-UTR,CDS,intron-Distal,intron-Proximal3.482385.15776HepG2BCLAF1
chr2216916174216916223-5'-UTR,CDS,intron-Distal3.107766.07405HepG2GRWD1
chr2216916187216916228-5'-UTR,CDS,intron-Distal4.0163318.76581HepG2BCLAF1
chr2216908618216908697-5'-UTR,CDS,intron-Distal,intron-Proximal3.3103915.81591HepG2PPIG
chr2216946431216946495-5'-UTR,CDS,intron-Distal,intron-Proximal4.515298.63366HepG2NCBP2
chr2216913984216914020-5'-UTR,CDS,intron-Distal,intron-Proximal3.357367.87154HepG2PPIG
chr2216946420216946493-5'-UTR,CDS,intron-Distal,intron-Proximal4.567674.38588HepG2DDX3X
chr2216914048216914088-5'-UTR,CDS,intron-Distal3.4447813.90696HepG2BCLAF1
chr2216916171216916187-5'-UTR,CDS,intron-Distal,intron-Proximal3.5416813.50876HepG2BCLAF1
chr2216908697216908740-5'-UTR,CDS,intron-Distal,intron-Proximal3.230289.91328HepG2PPIG
chr2216914088216914096-5'-UTR,CDS,intron-Distal3.461898.57930HepG2BCLAF1
chr2216931183216931301-CDS,intron-Distal,intron-Proximal3.876004.57180HepG2AQR
chr2216946364216946420-CDS,intron-Distal3.754113.68253HepG2DDX3X
chr2216923675216923699-CDS,intron-Distal3.424517.33138HepG2BCLAF1
chr2216946313216946369-CDS,intron-Distal3.339533.87906HepG2SRSF9
chr2216931156216931210-CDS,intron-Distal3.336708.34074HepG2PPIG
chr2216931107216931141-CDS,intron-Distal,intron-Proximal3.569969.83905HepG2BCLAF1
chr2216916239216916269-CDS,intron-Distal,intron-Proximal3.682213.80065HepG2PPIG
chr2216931159216931227-CDS,intron-Distal3.8431217.06349HepG2BCLAF1
chr2216923618216923634-CDS,intron-Distal4.218924.52024HepG2PPIG
chr2216930035216930072-CDS,intron-Distal4.0243713.87674HepG2BCLAF1
chr2216916228216916270-CDS,intron-Distal,intron-Proximal3.4371317.01386HepG2BCLAF1
chr2216923616216923639-CDS,intron-Distal,intron-Proximal3.441869.80919HepG2BCLAF1
chr2216923532216923594-intron-Distal,intron-Proximal3.058583.37783HepG2TIAL1
chr2216890489216890528-intron-Distal4.021413.62366HepG2HNRNPM
chr2216864119216864204-intron-Distal3.086824.63410HepG2SUGP2
chr2216941024216941144-intron-Distal4.466455.27745HepG2ILF3
chr2216945667216945732-intron-Distal3.494183.32156HepG2DDX59
chr2216873298216873380-intron-Distal3.555604.52901HepG2DDX59
chr2216926488216926595-intron-Distal5.563668.26701HepG2HNRNPL
chr2216895294216895373-intron-Distal3.387706.20894HepG2PTBP1
chr2216902232216902305-intron-Distal4.381544.17759HepG2QKI
chr2216880261216880366-intron-Distal3.858964.45128HepG2HNRNPL
chr2216945330216945394-intron-Distal4.770453.92947HepG2DDX59
chr2216898177216898244-intron-Distal3.124064.37446HepG2MATR3
chr2216877961216878037-CDS,intron-Distal3.070076.27275HepG2DDX3X
chr2216896489216896525-intron-Distal3.550517.02083HepG2PTBP1
chr2216873294216873379-intron-Distal3.828273.16533HepG2EIF3D
chr2216943419216943516-intron-Distal3.113043.78872HepG2DDX59
chr2216926657216926762-intron-Distal3.3514426.66398HepG2HNRNPL
chr2216923782216923867-intron-Distal,intron-Proximal3.139256.52355HepG2KHSRP
chr2216941981216942051-intron-Distal4.137477.36309HepG2DDX59
chr2216895004216895062-intron-Distal3.865273.60408HepG2XPO5
chr2216939166216939213-intron-Distal4.910986.42900HepG2PTBP1
chr2216905190216905285-intron-Distal4.239064.18168HepG2ILF3
chr2216923521216923601-intron-Distal,intron-Proximal3.869637.67357HepG2EFTUD2
chr2216942926216943003-intron-Distal3.173346.01439HepG2DDX59
chr2216896086216896145-intron-Distal6.9780058.75482HepG2PTBP1
chr2216896303216896374-intron-Distal5.7794613.69751HepG2PTBP1
chr2216860977216861018-intron-Distal,intron-Proximal3.017573.17233HepG2BCLAF1
chr2216889637216889731-intron-Distal4.6479410.21863HepG2PTBP1
chr2216896070216896137-intron-Distal4.961844.90095K562PTBP1
chr2216940518216940566-intron-Distal4.616733.44037HepG2DDX59
chr2216860961216861017-intron-Distal,intron-Proximal4.093783.61881HepG2TIAL1
chr2216892822216892923-intron-Distal3.457163.54383HepG2HNRNPL
chr2216895284216895392-intron-Distal4.422053.98468HepG2ILF3
chr2216908506216908556-intron-Distal,intron-Proximal3.384753.78824HepG2KHSRP
chr2216894391216894488-intron-Distal3.264103.61733HepG2XPO5
chr2216939105216939160-intron-Distal6.6628020.34407HepG2PTBP1
chr2216879854216879983-intron-Distal3.4100113.24933HepG2HNRNPL
chr2216874913216874981-intron-Distal3.777703.77855HepG2DDX59
chr2216891924216892002-intron-Distal3.888413.19026HepG2HNRNPL
chr2216924963216925031-intron-Distal3.002263.06355HepG2KHSRP
chr2216874637216874708-intron-Distal3.878513.77855HepG2DDX59
chr2216873180216873298-intron-Distal4.558053.77855HepG2DDX59
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PECR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PECR is not available on ENCORE database.

  • 138 RBPs can affect the levels of PECR.  








The Knockdown/knockout RNA-Seq assay for PECR is not available on ENCORE database.





138 RBPs can affect the gene expression of PECR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PECRENSG00000115425.9720.724701084.02430-0.588906.229904.68980HepG2AATF
PECRENSG00000115425.91950.348101472.882400.405003.140802.13540HepG2ABCF1
PECRENSG00000115425.9476.298401476.42110-1.6322072.5296070.50590HepG2ACO1
PECRENSG00000115425.9678.880704964.26740-2.87040102.1691099.75780HepG2AKAP1
PECRENSG00000115425.91359.272001974.48440-0.538604.924103.54910HepG2AKAP8
PECRENSG00000115425.91170.880901483.24600-0.341204.365503.41710HepG2AKAP8L
PECRENSG00000115425.93343.059304107.58420-0.297102.158401.46110HepG2ASCC1
PECRENSG00000115425.91920.19020911.237801.0752016.3669014.48070HepG2BCLAF1
PECRENSG00000115425.91686.60270988.184500.7712014.3760012.85690HepG2CALR
PECRENSG00000115425.91019.773701399.25570-0.456402.860401.86780HepG2CCAR1
PECRENSG00000115425.91829.220301475.965800.309504.890504.05390HepG2CKAP4
PECRENSG00000115425.91012.27590527.203100.941108.137207.01010HepG2CPSF6
PECRENSG00000115425.9360.81240647.76940-0.844208.711506.98030HepG2CSTF2
PECRENSG00000115425.9770.245801733.11160-1.1700036.8446035.04360HepG2CELF1
PECRENSG00000115425.93490.309501863.344100.9054047.8913045.59920HepG2DAZAP1
PECRENSG00000115425.91691.853001365.416200.309204.631703.59010HepG2DDX19B
PECRENSG00000115425.91240.38340906.967000.451602.524301.42070HepG2DDX1
PECRENSG00000115425.91662.249701195.692300.475205.027604.14170HepG2DDX21
PECRENSG00000115425.91734.188101170.338300.567207.928906.39940HepG2DDX24
PECRENSG00000115425.91709.95660964.758500.825608.185506.11230HepG2DDX27
PECRENSG00000115425.91084.36370781.096700.473203.473201.90750HepG2DDX28
PECRENSG00000115425.93148.401404755.54220-0.595006.960006.00950HepG2DDX3X
PECRENSG00000115425.9771.033401026.98440-0.413503.726402.16280HepG2DDX52
PECRENSG00000115425.9574.199301031.10070-0.844608.286507.02930HepG2DDX55
PECRENSG00000115425.92495.083701215.747201.0371020.2008017.85580HepG2DDX5
PECRENSG00000115425.91483.403804084.75680-1.4613030.5513028.82990HepG2DDX6
PECRENSG00000115425.91646.11790857.761800.9403017.1136015.04120HepG2DHX30
PECRENSG00000115425.92828.716601412.500101.0018032.5230030.86040HepG2DKC1
PECRENSG00000115425.91509.11670889.325800.7628016.1095014.54890HepG2DNAJC21
PECRENSG00000115425.91296.24370881.505500.5562011.6033010.36800HepG2DNAJC2
PECRENSG00000115425.91602.110401225.215500.386802.961202.00860HepG2EEF2
PECRENSG00000115425.92308.622103927.12550-0.7664011.074409.93620HepG2EIF2S1
PECRENSG00000115425.9814.289201117.11950-0.456204.814103.29600HepG2EIF2S2
PECRENSG00000115425.9517.95530994.54260-0.9412011.259509.57300HepG2EIF3D
PECRENSG00000115425.91396.503601129.312600.306302.596801.55040HepG2EIF3G
PECRENSG00000115425.92849.794204340.10440-0.606906.177205.22640HepG2EIF4A3
PECRENSG00000115425.9901.326304225.37790-2.2290051.5442048.92010HepG2EIF4B
PECRENSG00000115425.92563.454201838.455200.4795010.284008.86530HepG2EIF4G1
PECRENSG00000115425.92528.439601761.095200.521706.225405.02740HepG2EIF4G2
PECRENSG00000115425.91779.932801275.728800.480404.641003.26490HepG2ESF1
PECRENSG00000115425.91386.247802127.88230-0.6182014.2588013.06420HepG2ETF1
PECRENSG00000115425.91852.166001442.607900.360403.512302.56940HepG2EWSR1
PECRENSG00000115425.9639.52580888.99150-0.475204.836103.25300HepG2FAM120A
PECRENSG00000115425.91534.935601139.589500.429604.349802.96260HepG2FASTKD2
PECRENSG00000115425.9394.537101487.20550-1.9144039.8364037.60790HepG2FIP1L1
PECRENSG00000115425.91245.32800858.233200.537004.356702.78850HepG2FKBP4
PECRENSG00000115425.91130.44480528.181801.097705.747404.28770HepG2FTO
PECRENSG00000115425.9639.668801469.96770-1.2004014.1189011.86580HepG2FUS
PECRENSG00000115425.91378.523404378.47170-1.6673047.1704044.73920HepG2FXR1
PECRENSG00000115425.91915.311104061.94370-1.0846019.1980017.52180HepG2G3BP1
PECRENSG00000115425.9690.162601227.76370-0.831009.926807.96480HepG2GNB2L1
PECRENSG00000115425.9866.81240597.527000.536601.987301.43880HepG2GPKOW
PECRENSG00000115425.9659.746301665.03460-1.3356016.9116014.27510HepG2GRSF1
PECRENSG00000115425.9915.398701385.25130-0.597703.752501.92480HepG2GTF2F1
PECRENSG00000115425.91448.347201712.55170-0.241702.291901.43310HepG2HNRNPA2B1
PECRENSG00000115425.9481.99700998.69870-1.0510015.7122014.19120HepG2HNRNPC
PECRENSG00000115425.91698.60290862.513300.9776028.7121026.78450HepG2HNRNPF
PECRENSG00000115425.91604.255704112.45760-1.3581037.5759035.31300HepG2HNRNPK
PECRENSG00000115425.91357.284601697.31030-0.322504.903704.02600HepG2HNRNPL
PECRENSG00000115425.92017.49810570.240001.8228033.5799031.77550HepG2HNRNPLL
PECRENSG00000115425.9581.275701025.96310-0.8197012.2415010.48680HepG2HNRNPM
PECRENSG00000115425.91587.635602149.62190-0.437202.977701.69790HepG2HSPD1
PECRENSG00000115425.91900.74130849.323801.1621027.5188025.53100HepG2IGF2BP1
PECRENSG00000115425.92549.821904128.97280-0.695409.437508.27340HepG2IGF2BP2
PECRENSG00000115425.91609.504403874.47710-1.267407.830206.24090HepG2IGF2BP3
PECRENSG00000115425.91298.856201013.390500.358005.596404.58540HepG2ILF2
PECRENSG00000115425.92435.464701753.483700.473902.907701.54670HepG2ILF3
PECRENSG00000115425.92488.610504152.86200-0.738807.597405.85190HepG2KHSRP
PECRENSG00000115425.9977.251101477.59920-0.596504.664803.57830HepG2LARP4
PECRENSG00000115425.9713.973401202.76550-0.752409.811907.81030HepG2LARP7
PECRENSG00000115425.91828.121801263.006100.533406.193604.40750HepG2LIN28B
PECRENSG00000115425.93135.680404379.99800-0.482204.762603.90910HepG2MAGOH
PECRENSG00000115425.92202.297704404.59560-1.0000015.9511014.53240HepG2MATR3
PECRENSG00000115425.9523.722201040.83660-0.990908.096706.39450HepG2METAP2
PECRENSG00000115425.9945.268001203.41680-0.348303.111602.25600HepG2MSI2
PECRENSG00000115425.91378.06540581.786601.2440013.1072010.99000HepG2MTPAP
PECRENSG00000115425.91681.472404508.41620-1.4229032.8821030.90770HepG2NCBP2
PECRENSG00000115425.91269.377001847.69760-0.541608.325907.02540HepG2NOL12
PECRENSG00000115425.91204.35180505.698501.2518014.6619013.08560HepG2NSUN2
PECRENSG00000115425.92537.256404015.34950-0.662308.186906.95920HepG2PABPC4
PECRENSG00000115425.9503.15240981.99070-0.9647020.5323018.64830HepG2PARN
PECRENSG00000115425.92363.551104135.93630-0.8073016.2451014.97470HepG2PCBP1
PECRENSG00000115425.91905.649701154.192400.723307.109104.53040HepG2PHF6
PECRENSG00000115425.91294.53550884.867700.548808.338907.10700HepG2PPIL4
PECRENSG00000115425.92072.35990947.761601.1286041.7442039.50060HepG2PRPF4
PECRENSG00000115425.91827.871904208.27810-1.2031038.2028036.65440HepG2PTBP1
PECRENSG00000115425.91454.761101763.83790-0.277902.072401.54540HepG2PUF60
PECRENSG00000115425.91284.636601872.44900-0.5436013.2271012.13450HepG2PUM1
PECRENSG00000115425.91445.534101871.04570-0.372204.009803.20700HepG2PUM2
PECRENSG00000115425.92827.418801503.811000.9108037.9817036.20630HepG2PUS1
PECRENSG00000115425.93002.339404558.07780-0.6023012.0034010.83660HepG2QKI
PECRENSG00000115425.9447.432201342.88230-1.5856016.7915015.19430HepG2RAVER1
PECRENSG00000115425.91201.758701536.99550-0.355003.320902.39030HepG2RBM15
PECRENSG00000115425.9754.283201778.52440-1.2375039.7111038.19530HepG2RBM22
PECRENSG00000115425.92171.048004136.59410-0.9301024.2710022.39020HepG2RBM25
PECRENSG00000115425.9777.304501450.32590-0.8998012.4058010.29580HepG2RBM27
PECRENSG00000115425.91537.293004683.56880-1.6072049.0374047.41730HepG2NELFE
PECRENSG00000115425.92268.818904361.81880-0.9430027.7219026.13250HepG2RECQL
PECRENSG00000115425.91386.96390929.222300.577706.179605.21540HepG2RPLP0
PECRENSG00000115425.91979.146601319.100100.585203.847302.73380HepG2RPS10
PECRENSG00000115425.9346.53550967.79560-1.4817031.9343030.23090HepG2RPS19
PECRENSG00000115425.9982.355801365.38240-0.475003.975202.67140HepG2RPS5
PECRENSG00000115425.9539.05150786.80700-0.545603.662902.77580HepG2RRP9
PECRENSG00000115425.91438.02730883.498200.7027017.0396015.63710HepG2SAFB2
PECRENSG00000115425.91237.149202012.30090-0.701806.004504.98690HepG2SF3A3
PECRENSG00000115425.91745.83730564.367901.6291041.6621039.35270HepG2SF3B1
PECRENSG00000115425.91564.083704381.70460-1.4862048.2752046.40040HepG2SF3B4
PECRENSG00000115425.9439.986801021.24270-1.214803.920202.13260HepG2SFPQ
PECRENSG00000115425.93138.391101691.362900.8917043.7255041.64520HepG2SLBP
PECRENSG00000115425.9549.483001030.29740-0.9069022.7206021.15810HepG2SMN1
PECRENSG00000115425.9325.17380627.97870-0.949502.460901.72460HepG2SNRNP70
PECRENSG00000115425.91463.793302008.79310-0.456608.759208.00510HepG2SRFBP1
PECRENSG00000115425.91504.211004573.41050-1.6043054.6555053.14800HepG2SRSF1
PECRENSG00000115425.91124.374801741.60150-0.6313012.8256011.61010HepG2SRSF5
PECRENSG00000115425.91637.83210847.410300.9506027.0341025.29640HepG2SRSF7
PECRENSG00000115425.91424.539003720.59220-1.3850046.0453044.34400HepG2SRSF9
PECRENSG00000115425.94316.083201744.134601.3071082.7109080.91000HepG2SSB
PECRENSG00000115425.91109.885301571.57210-0.501803.485802.23830HepG2STIP1
PECRENSG00000115425.91460.893101980.62210-0.439108.399107.41380HepG2SUCLG1
PECRENSG00000115425.91709.194601004.035100.767405.933104.58400HepG2SUPT6H
PECRENSG00000115425.91335.362401026.439800.379502.396501.76140HepG2SUPV3L1
PECRENSG00000115425.92256.565704110.37020-0.8651024.3472022.91180HepG2TAF15
PECRENSG00000115425.91629.92880556.069401.5514037.2523035.17100HepG2TARDBP
PECRENSG00000115425.9485.77670687.98350-0.502103.107102.05210HepG2TFIP11
PECRENSG00000115425.92805.640203777.28360-0.429006.255905.00410HepG2TIA1
PECRENSG00000115425.9633.87910972.62590-0.617709.870908.90590HepG2TRIM56
PECRENSG00000115425.9566.151401093.94980-0.950302.800201.80320HepG2U2AF2
PECRENSG00000115425.9311.98080606.34610-0.958709.952408.51260HepG2UCHL5
PECRENSG00000115425.92118.010501784.602700.247003.217302.47520HepG2UPF1
PECRENSG00000115425.91143.955201834.32600-0.6812015.3514013.17020HepG2UTP18
PECRENSG00000115425.91300.583601722.96460-0.405706.669205.80810HepG2UTP3
PECRENSG00000115425.9767.495201320.50650-0.782906.355704.45650HepG2XRCC5
PECRENSG00000115425.9753.879301476.80510-0.970109.702507.85250HepG2XRCC6
PECRENSG00000115425.92215.781001010.417601.1328020.1256018.25510HepG2XRN2
PECRENSG00000115425.91478.67430935.286300.6607016.0406014.64210HepG2ZC3H8
PECRENSG00000115425.9116.71520174.42960-0.579701.794301.30140K562AQR
PECRENSG00000115425.987.36720150.54210-0.785003.534202.81000K562DDX47
PECRENSG00000115425.985.65200139.24540-0.701102.573601.98550K562FXR1
PECRENSG00000115425.9244.12820129.696700.912403.072401.76770K562HNRNPA2B1
PECRENSG00000115425.920.8289087.14760-2.064907.556306.61640K562HNRNPC
PECRENSG00000115425.9430.78540132.212801.7040020.7316018.71210K562HSPD1
PECRENSG00000115425.9263.75170134.810300.968203.367801.69790K562PPP1R8
PECRENSG00000115425.985.70790155.59800-0.860304.168103.37010K562PTBP1
PECRENSG00000115425.9220.84480305.71900-0.469201.867101.40380K562PUS1
PECRENSG00000115425.994.08490149.20680-0.665302.568801.76130K562RBM22
PECRENSG00000115425.976.90080152.53640-0.988104.439503.54800K562SRSF1
PECRENSG00000115425.9268.62210142.475200.914803.007701.50280K562SUPT6H
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PECR is not available on ENCORE database.





4 RBPs can affect the splicing of PECR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPECRENSG00000115425.9chr2-216923617216923699216916171216916268216930034216930200-0.059000.000010.00091excludedHepG2SF3A3
SEPECRENSG00000115425.9chr2-2169254322169255132169236172169236992169300342169302000.059000.000000.00000includedHepG2SF3B4
SEPECRENSG00000115425.9chr2-2169254322169255132169236172169236992169300342169302000.190000.000000.00000includedHepG2HNRNPC
SEPECRENSG00000115425.9chr2-2169254322169255132169236172169236992169300342169302000.812000.000140.00369includedK562HNRNPC
MXEPECRENSG00000115425.9chr2-216916171216916268216923617216923699216913985216914096216930034216930200-0.157000.007750.066462includedHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PECR is not avaliable on ENCORE database.