LRRC8B

General Information

Gene Name       : LRRC8B
Gene ID             : ENSG00000197147.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LRRC8B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LRRC8BENSG00000197147.134.873.664.27ENCSR000AEF
HepG2LRRC8BENSG00000197147.134.886.335.61ENCSR985KAT
K562LRRC8BENSG00000197147.1311.4110.7311.07ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LRRC8B is not avaliable on ENCORE database.



Proteins bound to RNA
  • LRRC8B RNA is bound by 16 proteins.  







eCLIP assay for LRRC8B is not avaliable on ENCORE database.





16 proteins are bound to LRRC8B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr19005943990059507+3'-UTR4.441695.66249K562TIA1
chr19005888290058932+3'-UTR4.127633.47885K562LIN28B
chr19006230190062395+3'-UTR4.170304.79477K562KHSRP
chr18999046789990582+5'-UTR,intron-Proximal4.194926.63000K562DDX3X
chr18999049089990579+5'-UTR4.834986.75419HepG2DDX3X
chr18999044889990563+5'-UTR3.641403.61570K562SRSF1
chr18999056389990708+5'-UTR,intron-Distal,intron-Proximal5.001996.85535K562SRSF1
chr19004830790048360+CDS4.060844.24775K562IGF2BP2
chr19004931490049393+CDS3.342143.69775K562YBX3
chr19004827590048370+CDS3.963693.64119HepG2UPF1
chr19004845090048535+CDS3.997413.02541K562IGF2BP2
chr18999380789993856+intron-Distal4.355674.49973K562MATR3
chr19001259090012698+intron-Distal3.287234.35941K562KHSRP
chr18999366989993759+intron-Distal3.399433.30286HepG2PTBP1
chr19003737890037464+intron-Distal5.427679.02315K562EXOSC5
chr18999396489994007+intron-Distal4.761573.18981K562PTBP1
chr19001984190019947+intron-Distal5.4609611.11632HepG2QKI
chr19000806190008145+intron-Distal3.991547.08696K562TARDBP
chr18999367189993759+intron-Distal3.761576.54730K562PTBP1
chr19001977790019942+intron-Distal5.2913020.90399K562QKI
chr18999365489993756+intron-Distal3.335038.47759K562MATR3
chr18999880689998962+intron-Distal3.296354.10487K562HNRNPK
chr19003816290038300+intron-Distal4.812746.41304K562EXOSC5
chr19003920790039315+intron-Distal4.154866.11515K562PTBP1
chr18999395689994020+intron-Distal3.613234.72029K562MATR3
chr19002521190025248+intron-Distal4.508004.74405K562AGGF1
chr19003722590037269+intron-Distal4.196273.30687K562EXOSC5
chr19002519190025288+intron-Distal4.144379.44663K562HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LRRC8B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LRRC8B is not available on ENCORE database.

  • 133 RBPs can affect the levels of LRRC8B.  








The Knockdown/knockout RNA-Seq assay for LRRC8B is not available on ENCORE database.





133 RBPs can affect the gene expression of LRRC8B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LRRC8BENSG00000197147.8345.10850481.22160-0.479702.249901.39660HepG2ABCF1
LRRC8BENSG00000197147.8504.50900410.395300.297802.002901.47040HepG2ACO1
LRRC8BENSG00000197147.8297.04580436.93040-0.556703.512702.40210HepG2ADAR
LRRC8BENSG00000197147.8182.06220409.02300-1.1678010.289908.84560HepG2ASCC1
LRRC8BENSG00000197147.8618.37000434.380100.509403.891902.23860HepG2ATP5C1
LRRC8BENSG00000197147.8228.75790499.55660-1.126808.779707.06850HepG2BCCIP
LRRC8BENSG00000197147.8608.55910460.227500.403002.812202.03420HepG2CALR
LRRC8BENSG00000197147.8958.23640333.240701.5237016.3234014.52360HepG2CNOT7
LRRC8BENSG00000197147.8356.30320486.47550-0.449302.502101.84260HepG2CPSF6
LRRC8BENSG00000197147.8162.37210308.64870-0.926706.103304.60500HepG2CSTF2
LRRC8BENSG00000197147.8435.82870546.71830-0.327002.071901.50170HepG2CELF1
LRRC8BENSG00000197147.8443.12670587.82000-0.407703.748402.90780HepG2DAZAP1
LRRC8BENSG00000197147.8219.91170380.40730-0.790605.997705.04290HepG2DDX21
LRRC8BENSG00000197147.8722.46100473.543400.609304.571503.78280HepG2DDX3X
LRRC8BENSG00000197147.8648.95560491.140200.401902.379201.65590HepG2DDX55
LRRC8BENSG00000197147.8275.57090406.75690-0.561702.863102.23570HepG2DDX6
LRRC8BENSG00000197147.8341.21600439.97450-0.366702.301701.65440HepG2DNAJC21
LRRC8BENSG00000197147.8189.31590436.07390-1.2038018.4893016.94940HepG2DNAJC2
LRRC8BENSG00000197147.8216.85840391.05180-0.850605.782204.94310HepG2EIF2S1
LRRC8BENSG00000197147.8490.43860365.112300.425602.779601.60710HepG2EIF2S2
LRRC8BENSG00000197147.8478.81740308.480700.634204.315603.20500HepG2EIF3D
LRRC8BENSG00000197147.8272.81980432.17100-0.663703.993903.22930HepG2EIF4A3
LRRC8BENSG00000197147.8836.71710420.754600.991708.475707.30530HepG2EIF4B
LRRC8BENSG00000197147.8432.07140579.95190-0.424703.471702.55010HepG2EIF4G1
LRRC8BENSG00000197147.8335.08220555.55110-0.729406.114804.92580HepG2EIF4G2
LRRC8BENSG00000197147.8920.49800485.936100.921509.133407.83880HepG2FIP1L1
LRRC8BENSG00000197147.8302.47340200.697700.591703.330402.47180HepG2FUBP3
LRRC8BENSG00000197147.8574.83700436.003700.398702.113701.50620HepG2FXR1
LRRC8BENSG00000197147.8392.12360274.659700.513602.640301.76630HepG2GEMIN5
LRRC8BENSG00000197147.8252.41800424.78660-0.750904.878303.52620HepG2GNB2L1
LRRC8BENSG00000197147.8304.82870551.48000-0.855306.759905.78630HepG2GPKOW
LRRC8BENSG00000197147.8747.62460448.467800.737204.078202.36630HepG2HLTF
LRRC8BENSG00000197147.8324.74080444.18940-0.451902.060601.49350HepG2HNRNPA1
LRRC8BENSG00000197147.8698.84710540.241000.371303.322702.31050HepG2HNRNPA2B1
LRRC8BENSG00000197147.8364.72240494.07340-0.437902.509701.84600HepG2HNRNPC
LRRC8BENSG00000197147.8451.55730288.647300.645503.669301.91060HepG2HNRNPD
LRRC8BENSG00000197147.8418.04200645.55970-0.626907.196706.11130HepG2HNRNPF
LRRC8BENSG00000197147.8339.59270535.44790-0.656907.497706.43620HepG2HNRNPL
LRRC8BENSG00000197147.8380.60300490.80730-0.366902.638002.04560HepG2HNRNPU
LRRC8BENSG00000197147.8355.53410635.69640-0.8383010.024608.72880HepG2IGF2BP1
LRRC8BENSG00000197147.8295.08140411.15000-0.478602.517001.86970HepG2IGF2BP2
LRRC8BENSG00000197147.8369.58810501.34430-0.439903.948203.08780HepG2ILF2
LRRC8BENSG00000197147.8492.04520324.861100.598903.046701.65020HepG2ILF3
LRRC8BENSG00000197147.8558.73580416.087500.425202.888601.73020HepG2LARP7
LRRC8BENSG00000197147.8305.69060436.99780-0.515602.822601.59660HepG2LIN28B
LRRC8BENSG00000197147.8823.28250438.603100.908408.725307.65580HepG2MATR3
LRRC8BENSG00000197147.8334.81250536.69440-0.680703.474302.38090HepG2MTPAP
LRRC8BENSG00000197147.8842.61590448.939800.908309.379608.25440HepG2NCBP2
LRRC8BENSG00000197147.8274.64830582.88300-1.0856015.3730013.64780HepG2NOL12
LRRC8BENSG00000197147.8323.95710466.63670-0.526503.015002.23480HepG2NSUN2
LRRC8BENSG00000197147.8571.52510399.833700.515303.203902.42840HepG2PABPC4
LRRC8BENSG00000197147.8268.37610405.64610-0.596004.675703.92100HepG2PCBP1
LRRC8BENSG00000197147.8300.20270442.83970-0.560802.685301.66220HepG2PCBP2
LRRC8BENSG00000197147.8346.01330437.76180-0.339302.045301.40310HepG2PPIL4
LRRC8BENSG00000197147.8846.16840412.799101.0354020.7603019.52790HepG2PTBP1
LRRC8BENSG00000197147.8909.17390590.679300.6221011.1802010.15640HepG2PUM1
LRRC8BENSG00000197147.8557.38320418.022700.415003.638702.95240HepG2PUS1
LRRC8BENSG00000197147.8618.79170427.326500.534002.256001.61470HepG2RAVER1
LRRC8BENSG00000197147.81173.04380735.245100.6739010.627909.75730HepG2RBM22
LRRC8BENSG00000197147.8768.37360405.702200.9213012.6951011.31270HepG2RBM25
LRRC8BENSG00000197147.8751.58890501.720300.583005.054603.69450HepG2RBM27
LRRC8BENSG00000197147.8660.70740459.373400.524205.324904.61390HepG2NELFE
LRRC8BENSG00000197147.8445.14330695.36070-0.643505.750004.81710HepG2RPLP0
LRRC8BENSG00000197147.8348.03180437.08860-0.328702.092601.51960HepG2SAFB2
LRRC8BENSG00000197147.8919.56550519.235900.824506.638305.56620HepG2SF3A3
LRRC8BENSG00000197147.8716.54310429.707200.7376010.167309.14040HepG2SF3B4
LRRC8BENSG00000197147.8622.35290509.724300.287902.215601.62970HepG2SMN1
LRRC8BENSG00000197147.8989.40890560.487700.819807.229205.55100HepG2SRSF3
LRRC8BENSG00000197147.8736.23470549.400700.422204.245203.49900HepG2SRSF5
LRRC8BENSG00000197147.8463.92300634.22600-0.451104.179503.35020HepG2SRSF7
LRRC8BENSG00000197147.8264.84670721.00080-1.4448033.1693031.84330HepG2SSB
LRRC8BENSG00000197147.8769.72130624.807900.300802.789702.16620HepG2SUCLG1
LRRC8BENSG00000197147.8334.67820488.96610-0.547002.449601.80800HepG2SUPV3L1
LRRC8BENSG00000197147.8303.49480403.25330-0.410002.267001.75070HepG2TAF15
LRRC8BENSG00000197147.8509.05980370.450800.458503.412202.48820HepG2TIA1
LRRC8BENSG00000197147.8279.29340476.93020-0.772007.581606.82890HepG2TIAL1
LRRC8BENSG00000197147.8348.00840481.17300-0.467403.925503.27770HepG2TRIM56
LRRC8BENSG00000197147.8381.21780245.118600.637003.555501.78060HepG2TROVE2
LRRC8BENSG00000197147.8252.18780415.73120-0.721204.744103.93410HepG2U2AF1
LRRC8BENSG00000197147.8256.85550447.85800-0.802103.907102.70300HepG2UPF2
LRRC8BENSG00000197147.8282.72580473.30280-0.743407.615405.98360HepG2UTP18
LRRC8BENSG00000197147.8940.68650444.577301.0812024.5308023.01520HepG2UTP3
LRRC8BENSG00000197147.8831.43470469.969600.822906.390304.82800HepG2XRCC6
LRRC8BENSG00000197147.8236.50980481.33220-1.025108.008906.78670HepG2XRN2
LRRC8BENSG00000197147.8849.36510506.442500.7459014.1640013.16710HepG2ZNF622
LRRC8BENSG00000197147.81577.82150849.598200.8930015.2861012.64050K562AARS
LRRC8BENSG00000197147.8326.49780568.15030-0.799203.264401.38710K562ADAR
LRRC8BENSG00000197147.8677.651101049.66940-0.631309.950807.19060K562AKAP1
LRRC8BENSG00000197147.8817.477201942.56910-1.2487027.4027025.75540K562AQR
LRRC8BENSG00000197147.8741.085501042.07440-0.491706.022403.96930K562BCCIP
LRRC8BENSG00000197147.81516.581401157.180800.390102.883701.43280K562BUD13
LRRC8BENSG00000197147.82397.620101776.822100.432204.529802.88260K562CIRBP
LRRC8BENSG00000197147.8732.00400914.37230-0.320902.341301.61360K562CPSF6
LRRC8BENSG00000197147.8421.29220763.98010-0.8587012.088209.68720K562CSTF2
LRRC8BENSG00000197147.81991.823402761.03800-0.471107.133305.59080K562CELF1
LRRC8BENSG00000197147.8738.419801032.40090-0.483505.832704.03390K562DDX21
LRRC8BENSG00000197147.8870.583201126.97530-0.372403.945101.78400K562DDX24
LRRC8BENSG00000197147.81446.676201063.600500.443704.831303.40210K562DDX3X
LRRC8BENSG00000197147.81219.275701883.64420-0.6275011.9469010.69520K562DDX47
LRRC8BENSG00000197147.8437.43810622.73400-0.509502.809201.46960K562DHX30
LRRC8BENSG00000197147.8386.21270634.14050-0.715403.651201.61110K562DNAJC2
LRRC8BENSG00000197147.8829.243801040.17420-0.327002.969702.14560K562EIF3G
LRRC8BENSG00000197147.8846.251801111.20890-0.393003.227002.34320K562EIF4A3
LRRC8BENSG00000197147.81790.114702245.45780-0.327004.167703.02100K562EIF4G2
LRRC8BENSG00000197147.8721.06680969.97780-0.427804.130002.50450K562EWSR1
LRRC8BENSG00000197147.8687.203701115.06080-0.698309.628407.28590K562EXOSC5
LRRC8BENSG00000197147.81126.88360813.878100.469403.379101.44700K562FAM120A
LRRC8BENSG00000197147.81222.60380807.235200.598805.568703.86790K562FKBP4
LRRC8BENSG00000197147.81268.34600930.384900.446903.898602.87970K562FMR1
LRRC8BENSG00000197147.81376.00220919.547600.581404.712302.92450K562FUS
LRRC8BENSG00000197147.81622.699501146.521100.501003.440902.63550K562G3BP2
LRRC8BENSG00000197147.8981.599501600.72260-0.7055010.377308.88810K562GRSF1
LRRC8BENSG00000197147.8699.808601136.79240-0.699909.926208.04820K562HNRNPA1
LRRC8BENSG00000197147.8506.31580929.41490-0.8763012.1795011.00220K562HNRNPC
LRRC8BENSG00000197147.82410.742301655.904500.541805.803903.94590K562HNRNPK
LRRC8BENSG00000197147.81170.175601702.39500-0.540806.924005.17870K562HNRNPL
LRRC8BENSG00000197147.8950.526201258.84830-0.405304.649103.48480K562HNRNPU
LRRC8BENSG00000197147.81137.996801619.01730-0.508603.245602.38590K562HSPD1
LRRC8BENSG00000197147.81296.363801685.98460-0.379103.515002.13200K562IGF2BP3
LRRC8BENSG00000197147.8363.20960561.76920-0.629204.883902.92130K562KHDRBS1
LRRC8BENSG00000197147.81141.396101676.53930-0.554704.703602.22860K562KHSRP
LRRC8BENSG00000197147.81181.96170900.302300.392603.221301.69400K562LARP7
LRRC8BENSG00000197147.8601.68410942.84070-0.648006.251603.92180K562LIN28B
LRRC8BENSG00000197147.81284.831801742.32090-0.439404.773603.66210K562MAGOH
LRRC8BENSG00000197147.81166.754101738.85630-0.575608.060206.38510K562MATR3
LRRC8BENSG00000197147.82364.050801711.501000.465906.089004.63820K562MBNL1
LRRC8BENSG00000197147.8680.59190852.13840-0.324302.175601.39790K562METAP2
LRRC8BENSG00000197147.8997.293001341.48110-0.427706.223605.05160K562MTPAP
LRRC8BENSG00000197147.81579.119501109.596800.509006.773004.88150K562NCBP2
LRRC8BENSG00000197147.8954.346601490.50510-0.6432016.8980015.26230K562NSUN2
LRRC8BENSG00000197147.81348.948301702.89630-0.336203.301101.81990K562PCBP1
LRRC8BENSG00000197147.8768.971901418.35280-0.8832011.356509.67200K562PCBP3
LRRC8BENSG00000197147.8659.98930907.47070-0.459403.724102.02680K562PHF6
LRRC8BENSG00000197147.81607.726102307.28140-0.521207.869805.67840K562PNPT1
LRRC8BENSG00000197147.8615.731901087.92540-0.8212013.0519011.37880K562POLR2G
LRRC8BENSG00000197147.82518.627001692.739400.573209.188008.02440K562PTBP1
LRRC8BENSG00000197147.81825.476102449.95350-0.424504.738803.67430K562PUF60
LRRC8BENSG00000197147.82547.331401093.933301.2194013.1350010.06070K562RAVER1
LRRC8BENSG00000197147.81135.935001391.07000-0.292302.653902.07180K562RBM15
LRRC8BENSG00000197147.8641.75590906.43320-0.498203.139502.26620K562RPS19
LRRC8BENSG00000197147.8654.99820909.86130-0.474202.583301.30200K562RRP9
LRRC8BENSG00000197147.8708.19180969.36640-0.452903.972502.66600K562SAFB
LRRC8BENSG00000197147.8844.877801260.40230-0.577103.291301.61460K562SBDS
LRRC8BENSG00000197147.81174.68660830.291000.500503.695402.56430K562SF3B1
LRRC8BENSG00000197147.8413.71380612.80690-0.566804.430402.78920K562SLBP
LRRC8BENSG00000197147.81380.063401065.566900.373003.351401.30650K562SLTM
LRRC8BENSG00000197147.81742.693801506.814600.209702.359901.48610K562SRPK2
LRRC8BENSG00000197147.8971.884901659.39730-0.7718013.3388011.78770K562SRSF1
LRRC8BENSG00000197147.8658.23550921.32730-0.485105.680303.98570K562SRSF7
LRRC8BENSG00000197147.8675.203501072.92400-0.668208.741506.37140K562SSB
LRRC8BENSG00000197147.8777.112901091.21690-0.489705.383204.23110K562SYNCRIP
LRRC8BENSG00000197147.8991.686701679.52970-0.7601010.391408.87860K562TARDBP
LRRC8BENSG00000197147.81326.573801620.06680-0.288302.400601.64480K562TIA1
LRRC8BENSG00000197147.8502.39540801.52230-0.673905.864804.45030K562TIAL1
LRRC8BENSG00000197147.81704.025701147.833700.569908.585607.15600K562U2AF2
LRRC8BENSG00000197147.8816.739201580.41430-0.9524028.8840026.87080K562UPF1
LRRC8BENSG00000197147.8891.733201352.31050-0.600707.987706.45610K562WDR3
LRRC8BENSG00000197147.8986.287901406.24670-0.511809.640708.16690K562WDR43
LRRC8BENSG00000197147.81690.83500894.391000.918704.634602.37150K562XPO5
LRRC8BENSG00000197147.81719.532902188.39650-0.347902.553001.73100K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LRRC8B is not available on ENCORE database.






No RBPs affect the alternative splcing events of LRRC8B on ENCORE database.





The Knockdown/knockout RNA-Seq assay for LRRC8B is not avaliable on ENCORE database.