EDEM3

General Information

Gene Name       : EDEM3
Gene ID             : ENSG00000116406.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EDEM3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EDEM3ENSG00000116406.1810.279.7310.00ENCSR000AEF
HepG2EDEM3ENSG00000116406.1812.5510.6311.59ENCSR985KAT
K562EDEM3ENSG00000116406.1816.1021.2418.67ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EDEM3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EDEM3 RNA is bound by 13 proteins.  







eCLIP assay for EDEM3 is not avaliable on ENCORE database.





13 proteins are bound to EDEM3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1184659765184659788-3'-UTR,intron-Distal3.761713.39866K562LSM11
chr1184659687184659913-3'-UTR,intron-Distal4.7003011.64294K562CPSF6
chr1184661875184661917-3'-UTR,intron-Distal3.9995811.58326K562UPF1
chr1184661594184661639-3'-UTR,intron-Distal4.6540916.08546K562PUM2
chr1184661874184661914-3'-UTR,intron-Distal3.039417.18667K562FAM120A
chr1184659727184659765-3'-UTR,intron-Distal3.640734.93068K562LSM11
chr1184659788184659842-3'-UTR,intron-Distal5.3735816.31233K562LSM11
chr1184661104184661135-3'-UTR,intron-Distal4.016166.14808K562UPF1
chr1184659716184659764-3'-UTR,intron-Distal5.8102847.66756K562PUM2
chr1184660650184660725-3'-UTR,intron-Distal3.0338314.42441K562UPF1
chr1184659972184659995-3'-UTR,intron-Distal4.380098.16666K562FAM120A
chr1184659758184659883-3'-UTR,intron-Distal4.705345.08199HepG2FUBP3
chr1184661380184661429-3'-UTR,intron-Distal3.482617.91779K562UPF1
chr1184659713184659889-3'-UTR,intron-Distal4.354843.71057HepG2LSM11
chr1184661088184661136-3'-UTR,intron-Distal3.617057.65557K562FAM120A
chr1184659810184659860-3'-UTR,intron-Distal5.655359.86388K562PUM2
chr1184661806184661853-3'-UTR,intron-Distal3.483396.84281K562UPF1
chr1184662901184662986-3'-UTR,intron-Distal,intron-Proximal3.204987.57209K562FAM120A
chr1184659758184659844-3'-UTR,intron-Distal4.0166116.63347K562KHSRP
chr1184659951184659972-3'-UTR,intron-Distal3.764427.34697K562FAM120A
chr1184661237184661301-3'-UTR,intron-Distal3.283768.42351K562FAM120A
chr1184659686184659716-3'-UTR,intron-Distal6.5283230.16250K562PUM2
chr1184662905184662982-3'-UTR,intron-Distal,intron-Proximal3.748183.56497HepG2FAM120A
chr1184662915184663057-3'-UTR,intron-Distal,intron-Proximal3.220973.73678HepG2UPF1
chr1184661815184661845-3'-UTR,intron-Distal5.241527.73381K562FAM120A
chr1184663133184663234-3'-UTR,CDS,intron-Distal,intron-Proximal5.319368.07539HepG2BCLAF1
chr1184723931184723982-5'-UTR,intron-Distal4.084955.48791HepG2DDX3X
chr1184723919184723982-5'-UTR,intron-Distal4.437504.54835K562NCBP2
chr1184723649184723699-5'-UTR,CDS,intron-Distal4.973756.05264HepG2DDX3X
chr1184723650184723764-5'-UTR,CDS,intron-Distal,intron-Proximal3.052634.39112K562DDX3X
chr1184723717184723814-5'-UTR,CDS,intron-Distal,intron-Proximal4.266238.97908HepG2DDX3X
chr1184723908184723984-5'-UTR,intron-Distal3.329383.77385HepG2NCBP2
chr1184690422184690521-CDS,intron-Distal,intron-Proximal3.737866.39464HepG2BCLAF1
chr1184663327184663397-CDS,intron-Distal4.3980610.00297K562PUM2
chr1184718682184718751-CDS,intron-Distal,intron-Proximal3.709314.36528HepG2U2AF2
chr1184701863184701975-CDS,intron-Distal,intron-Proximal3.428164.06013K562PRPF8
chr1184695339184695421-CDS,intron-Distal,intron-Proximal3.199704.76426K562PRPF8
chr1184701959184702010-CDS,intron-Distal,intron-Proximal3.359823.57857HepG2BCLAF1
chr1184671852184671920-intron-Distal,intron-Proximal3.666843.26999K562KHSRP
chr1184663939184663990-intron-Distal3.607853.06150K562KHSRP
chr1184678267184678399-intron-Distal4.422344.07628HepG2PTBP1
chr1184701508184701586-intron-Distal3.366074.10408K562KHSRP
chr1184667888184667940-intron-Distal5.068336.19339K562PTBP1
chr1184664607184664697-intron-Distal4.059203.25538K562KHSRP
chr1184720676184720757-intron-Distal4.237809.41035K562KHSRP
chr1184678285184678346-intron-Distal4.167303.30744K562PTBP1
chr1184720613184720676-intron-Distal4.708946.07567K562KHSRP
chr1184720481184720613-intron-Distal3.8934012.80002K562KHSRP
chr1184681311184681372-intron-Distal4.408864.45977HepG2U2AF2
chr1184713302184713381-intron-Distal4.363005.68841K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EDEM3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EDEM3 is not available on ENCORE database.

  • 124 RBPs can affect the levels of EDEM3.  








The Knockdown/knockout RNA-Seq assay for EDEM3 is not available on ENCORE database.





124 RBPs can affect the gene expression of EDEM3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EDEM3ENSG00000116406.14964.33370673.137400.518504.284202.97720HepG2AATF
EDEM3ENSG00000116406.141203.89520957.447900.330304.076703.36550HepG2ACO1
EDEM3ENSG00000116406.14582.73970754.61350-0.372902.343101.42310HepG2ADAR
EDEM3ENSG00000116406.142663.382701465.167900.8621010.786509.80300HepG2AKAP1
EDEM3ENSG00000116406.141879.682001212.324100.632606.952805.73270HepG2ASCC1
EDEM3ENSG00000116406.142072.484001253.083700.7258018.6147017.13030HepG2AUH
EDEM3ENSG00000116406.14580.48910825.57860-0.508102.632201.72040HepG2BCCIP
EDEM3ENSG00000116406.141198.35560717.449800.740008.195906.75380HepG2BCLAF1
EDEM3ENSG00000116406.141259.03080964.359800.384603.138002.50500HepG2BOP1
EDEM3ENSG00000116406.141752.80960817.262101.1007012.1272010.70230HepG2CALR
EDEM3ENSG00000116406.14697.84270957.32920-0.456106.447505.50890HepG2CKAP4
EDEM3ENSG00000116406.141848.84110885.332801.0622019.5879017.96370HepG2CPSF6
EDEM3ENSG00000116406.141555.08560930.563600.7407015.1540013.88760HepG2CELF1
EDEM3ENSG00000116406.141321.078901000.812000.400405.621604.61610HepG2DAZAP1
EDEM3ENSG00000116406.14674.28520885.54320-0.393204.872203.80610HepG2DDX19B
EDEM3ENSG00000116406.141197.15880726.833300.7198010.076408.38610HepG2DDX24
EDEM3ENSG00000116406.142532.537801403.564300.8514012.1524010.92750HepG2DDX3X
EDEM3ENSG00000116406.141448.275201005.361100.526502.450101.53080HepG2DDX59
EDEM3ENSG00000116406.141156.65850786.633400.556105.362504.00070HepG2DDX5
EDEM3ENSG00000116406.14609.43910753.14950-0.305502.928102.26030HepG2DNAJC2
EDEM3ENSG00000116406.141015.54400683.996700.570103.931502.59930HepG2AGO1
EDEM3ENSG00000116406.141866.365201159.063100.687207.808706.84780HepG2EIF2S1
EDEM3ENSG00000116406.141716.966701280.951100.422503.024302.35630HepG2EIF4A3
EDEM3ENSG00000116406.141310.43440987.166400.408604.910803.84750HepG2EIF4G1
EDEM3ENSG00000116406.141528.88410945.677400.693008.242306.86920HepG2EIF4G2
EDEM3ENSG00000116406.141902.857201438.731400.403306.498505.64150HepG2ETF1
EDEM3ENSG00000116406.14656.51460935.67700-0.511205.050803.92580HepG2EWSR1
EDEM3ENSG00000116406.141551.08410886.854500.806403.566602.40790HepG2FTO
EDEM3ENSG00000116406.141165.52230651.795400.8384012.4791010.86740HepG2FUBP3
EDEM3ENSG00000116406.14768.124001292.27430-0.750508.441207.28700HepG2FXR1
EDEM3ENSG00000116406.14382.88200514.50650-0.426302.524601.67370HepG2GEMIN5
EDEM3ENSG00000116406.14899.575801306.85210-0.538803.316702.09220HepG2GRSF1
EDEM3ENSG00000116406.141218.02690914.142900.414005.252603.95340HepG2HDGF
EDEM3ENSG00000116406.141285.42220919.665100.483006.380205.06200HepG2HNRNPA2B1
EDEM3ENSG00000116406.141295.09150853.300300.601806.734705.69150HepG2HNRNPC
EDEM3ENSG00000116406.141400.65300957.743200.548305.272604.43350HepG2HNRNPLL
EDEM3ENSG00000116406.14615.46910865.85540-0.492407.183806.06230HepG2ILF2
EDEM3ENSG00000116406.14938.114301299.98470-0.470703.330202.64350HepG2MATR3
EDEM3ENSG00000116406.14784.45370992.39090-0.339202.987202.19540HepG2NOL12
EDEM3ENSG00000116406.141102.12370849.226500.376002.590801.86610HepG2NSUN2
EDEM3ENSG00000116406.141904.845401185.101900.684607.780506.58420HepG2PABPC4
EDEM3ENSG00000116406.14588.21410839.03710-0.512406.268205.07260HepG2PARN
EDEM3ENSG00000116406.14684.670101144.62350-0.7414014.6470013.43110HepG2PCBP1
EDEM3ENSG00000116406.141414.51280951.688600.571603.615502.43650HepG2PCBP2
EDEM3ENSG00000116406.14608.86600756.04390-0.312302.447301.74950HepG2PPIL4
EDEM3ENSG00000116406.14876.41250654.768400.420504.524003.55920HepG2PRPF4
EDEM3ENSG00000116406.14796.73080626.382600.346902.322401.57910HepG2PRPF8
EDEM3ENSG00000116406.141832.208101005.485200.8656029.6472028.12230HepG2PUM1
EDEM3ENSG00000116406.14765.71620975.23580-0.348903.994103.27930HepG2PUS1
EDEM3ENSG00000116406.142117.789101261.411900.7474015.7077014.39630HepG2QKI
EDEM3ENSG00000116406.141801.784201144.800100.654209.913008.69290HepG2RBM25
EDEM3ENSG00000116406.141121.220201296.19190-0.209201.814401.35620HepG2NELFE
EDEM3ENSG00000116406.141316.38550902.037600.545203.224802.20610HepG2RPS10
EDEM3ENSG00000116406.14407.23130562.26780-0.465403.150502.50080HepG2RPS19
EDEM3ENSG00000116406.14812.44670619.646000.390702.541801.78490HepG2RRP9
EDEM3ENSG00000116406.141563.62170947.973400.721909.572008.33500HepG2SF3B1
EDEM3ENSG00000116406.141241.68920908.123600.451206.676305.66210HepG2SLBP
EDEM3ENSG00000116406.14707.93210880.31490-0.314403.371502.67280HepG2SMN1
EDEM3ENSG00000116406.14529.85420935.84090-0.820706.953905.38140HepG2SMNDC1
EDEM3ENSG00000116406.142395.611201054.787801.1833013.4396011.73740HepG2SNRNP70
EDEM3ENSG00000116406.141774.214801358.180200.385406.145305.47970HepG2SRFBP1
EDEM3ENSG00000116406.141459.49300935.193400.6420012.0810010.89990HepG2SRSF5
EDEM3ENSG00000116406.141507.597401029.698900.5499010.714809.75250HepG2SRSF9
EDEM3ENSG00000116406.141015.906701179.20680-0.215001.911301.46450HepG2SSB
EDEM3ENSG00000116406.141320.23020858.356800.621004.110502.63020HepG2SUB1
EDEM3ENSG00000116406.141047.47390703.428700.574306.824505.39280HepG2SUPT6H
EDEM3ENSG00000116406.141013.24870808.076000.326302.128101.52450HepG2SUPV3L1
EDEM3ENSG00000116406.141483.895101137.623100.383304.552203.86090HepG2TAF15
EDEM3ENSG00000116406.141222.85240933.517700.389403.107002.34440HepG2TARDBP
EDEM3ENSG00000116406.14702.56340541.668300.375102.277901.36660HepG2TFIP11
EDEM3ENSG00000116406.141395.919801045.353600.417104.379803.33610HepG2TIA1
EDEM3ENSG00000116406.14663.95900823.65890-0.311002.225601.76750HepG2TIAL1
EDEM3ENSG00000116406.141603.04770979.349700.710806.597505.27400HepG2UBE2L3
EDEM3ENSG00000116406.14200.89120477.40390-1.2488012.6583011.05920HepG2UCHL5
EDEM3ENSG00000116406.141241.476101056.226100.233002.248801.60840HepG2UPF1
EDEM3ENSG00000116406.14449.15530740.13720-0.720603.210602.12820HepG2UPF2
EDEM3ENSG00000116406.14385.41490795.46010-1.045408.013006.78990HepG2XRN2
EDEM3ENSG00000116406.14867.37760646.189600.424605.085104.22200HepG2ZC3H8
EDEM3ENSG00000116406.14771.751701161.64390-0.5900011.8717010.93580HepG2ZNF622
EDEM3ENSG00000116406.142612.110303226.13820-0.304602.585101.41140K562ABCF1
EDEM3ENSG00000116406.141217.700702617.05330-1.1038045.0787042.83550K562AGGF1
EDEM3ENSG00000116406.142258.009302875.65180-0.348803.432902.31160K562AKAP8
EDEM3ENSG00000116406.141528.282002723.13940-0.8334011.8108010.33320K562AKAP8L
EDEM3ENSG00000116406.142480.380402959.98680-0.255001.924501.41850K562AQR
EDEM3ENSG00000116406.142623.271903127.59750-0.253702.524701.40890K562CCDC124
EDEM3ENSG00000116406.141624.747502385.40130-0.554004.134502.30870K562CKAP4
EDEM3ENSG00000116406.141771.246502727.44660-0.6228014.2089011.77730K562CPEB4
EDEM3ENSG00000116406.141029.397301247.95640-0.277802.364001.39960K562CSTF2
EDEM3ENSG00000116406.142393.586903070.51810-0.359303.330801.71860K562DDX19B
EDEM3ENSG00000116406.141450.967001742.97710-0.264502.856401.62440K562DDX21
EDEM3ENSG00000116406.141327.352701605.62710-0.274602.737601.44170K562DDX6
EDEM3ENSG00000116406.141470.626601739.36250-0.242102.721001.52730K562EIF2S1
EDEM3ENSG00000116406.141183.745101763.94420-0.575409.783908.28410K562EIF3G
EDEM3ENSG00000116406.141064.759501489.90230-0.484706.915004.96130K562EIF4B
EDEM3ENSG00000116406.14918.831001444.17020-0.6524010.799307.94730K562EWSR1
EDEM3ENSG00000116406.141310.930602318.96260-0.8229014.1358012.06450K562FIP1L1
EDEM3ENSG00000116406.141083.188401560.84870-0.527007.943304.83880K562FUBP3
EDEM3ENSG00000116406.141555.041802084.17260-0.422504.714102.79490K562G3BP1
EDEM3ENSG00000116406.141993.726101594.664200.322102.756601.96340K562GPKOW
EDEM3ENSG00000116406.141969.768002905.61120-0.560804.152503.22980K562GRSF1
EDEM3ENSG00000116406.141744.147301323.526200.398004.172903.45520K562HNRNPC
EDEM3ENSG00000116406.14780.411701181.79410-0.598706.826004.95350K562HNRNPF
EDEM3ENSG00000116406.141437.157001907.32750-0.408303.098102.10900K562HNRNPM
EDEM3ENSG00000116406.142252.131503144.09450-0.481405.753604.62120K562HSPD1
EDEM3ENSG00000116406.141540.086002179.61370-0.501104.029102.69430K562IGF2BP2
EDEM3ENSG00000116406.142040.403002890.01270-0.502206.702905.29030K562KIF1C
EDEM3ENSG00000116406.141956.603602766.38750-0.499706.001804.19360K562MAK16
EDEM3ENSG00000116406.141917.534302286.48370-0.253902.153701.35010K562MATR3
EDEM3ENSG00000116406.142663.303303237.53290-0.281702.772301.86290K562MBNL1
EDEM3ENSG00000116406.14780.027601556.59190-0.9968018.8033016.44830K562METAP2
EDEM3ENSG00000116406.142251.991203723.87020-0.725607.446105.64330K562MSI2
EDEM3ENSG00000116406.141615.890202269.26890-0.489903.551002.52340K562NAA15
EDEM3ENSG00000116406.141661.908302042.16540-0.297305.426704.43350K562NSUN2
EDEM3ENSG00000116406.14995.031501302.95910-0.389002.803301.37300K562NUSAP1
EDEM3ENSG00000116406.141421.537602092.28550-0.557602.390501.48440K562PABPN1
EDEM3ENSG00000116406.141573.576402239.33570-0.509007.304405.04510K562PCBP1
EDEM3ENSG00000116406.14996.012601292.08300-0.375502.955301.47410K562PHF6
EDEM3ENSG00000116406.141419.026901117.265600.344803.432002.53280K562POLR2G
EDEM3ENSG00000116406.141424.930802632.40570-0.8855015.8714013.38750K562PPIG
EDEM3ENSG00000116406.14830.086301186.64750-0.515604.865803.62350K562PSIP1
EDEM3ENSG00000116406.141663.894802225.89220-0.419805.101404.22290K562PTBP1
EDEM3ENSG00000116406.144900.820103811.784800.362504.229503.22620K562PUF60
EDEM3ENSG00000116406.14987.482702700.77290-1.4515039.3762037.27910K562PUS1
EDEM3ENSG00000116406.141648.823302631.35890-0.6744014.8903013.50020K562RBM15
EDEM3ENSG00000116406.141391.056102134.57510-0.617807.620906.13720K562RBM22
EDEM3ENSG00000116406.141094.483201670.27650-0.609803.731402.15600K562RBM25
EDEM3ENSG00000116406.141298.522801788.30670-0.461703.176801.35040K562RECQL
EDEM3ENSG00000116406.141267.17180995.413300.348102.802401.71260K562SAFB
EDEM3ENSG00000116406.141378.101601830.86690-0.409802.891802.01610K562SF3B4
EDEM3ENSG00000116406.141432.217602333.13430-0.704003.141801.71970K562SFPQ
EDEM3ENSG00000116406.14735.357801026.20290-0.480803.575202.36580K562SRFBP1
EDEM3ENSG00000116406.141548.248502060.69690-0.412503.987802.68650K562SRSF5
EDEM3ENSG00000116406.141421.257401819.52770-0.356404.565202.86250K562SSB
EDEM3ENSG00000116406.141628.807801120.603700.539407.610406.23870K562SYNCRIP
EDEM3ENSG00000116406.141692.939702208.49360-0.383503.353502.57260K562TARDBP
EDEM3ENSG00000116406.14775.093601141.37540-0.558304.834003.56720K562TIAL1
EDEM3ENSG00000116406.141604.869602090.25420-0.381203.337902.11760K562TRA2A
EDEM3ENSG00000116406.14866.579401212.38950-0.484404.563803.27950K562TRIM56
EDEM3ENSG00000116406.141674.102902125.30530-0.344304.167402.60920K562TROVE2
EDEM3ENSG00000116406.14836.400101426.88230-0.770606.622404.97070K562UCHL5
EDEM3ENSG00000116406.141831.254002738.13460-0.580402.780601.48270K562UTP18
EDEM3ENSG00000116406.141343.913401852.82310-0.463305.558604.29720K562WDR3
EDEM3ENSG00000116406.142414.504203334.80740-0.465905.065103.84170K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EDEM3 is not available on ENCORE database.





2 RBPs can affect the splicing of EDEM3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEDEM3ENSG00000116406.14chr1-1846778161846779491846772861846774781846795271846796810.070000.000650.07662includedK562RBM22
A3SSEDEM3ENSG00000116406.14chr1-1846882951846884051846882951846883791846885761846887510.054000.000600.00438longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EDEM3 is not avaliable on ENCORE database.