APOE

General Information

Gene Name       : APOE
Gene ID             : ENSG00000130203.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: APOE)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878APOEENSG00000130203.90.000.020.01ENCSR000AEF
HepG2APOEENSG00000130203.9668.10128.37398.24ENCSR985KAT
K562APOEENSG00000130203.923.6411.7817.71ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for APOE is not avaliable on ENCORE database.



Proteins bound to RNA
  • APOE RNA is bound by 19 proteins.  







eCLIP assay for APOE is not avaliable on ENCORE database.





19 proteins are bound to APOE RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194541259745412621+3'-UTR4.79657400.00000HepG2LARP4
chr194541254245412611+3'-UTR4.716806.34161K562PCBP1
chr194541247545412581+3'-UTR,CDS3.339545.60676K562DDX55
chr194541254345412566+3'-UTR3.85595400.00000HepG2LARP4
chr194541251545412621+3'-UTR4.23373400.00000HepG2PCBP1
chr194541258045412597+3'-UTR4.42526400.00000HepG2LARP4
chr194541253545412543+3'-UTR3.66688400.00000HepG2LARP4
chr194541250445412574+3'-UTR3.74051400.00000HepG2RPS3
chr194541252445412535+3'-UTR3.76617400.00000HepG2LARP4
chr194541249745412524+3'-UTR,CDS3.89954400.00000HepG2LARP4
chr194541258145412594+3'-UTR3.3334256.42327HepG2RPS3
chr194541256645412580+3'-UTR3.92529400.00000HepG2LARP4
chr194540986245409925+5'-UTR,CDS,intron-Proximal5.4728024.54154K562LIN28B
chr194540987445409924+5'-UTR,CDS3.5100326.51234HepG2LIN28B
chr194540909545409098+5'-UTR4.34912400.00000HepG2DDX3X
chr194540905445409095+5'-UTR4.64198400.00000HepG2DDX3X
chr194540910445409126+5'-UTR,intron-Proximal4.171313.59236HepG2AQR
chr194540980345409888+5'-UTR,CDS,intron-Proximal4.820454.40745K562SF3B4
chr194540988045409904+5'-UTR,CDS4.253405.21590K562DDX3X
chr194540986045409880+5'-UTR,CDS4.33669400.00000HepG2DDX3X
chr194540985845409860+5'-UTR,CDS,intron-Proximal4.54493400.00000HepG2DDX3X
chr194541189545411928+CDS5.14319400.00000HepG2SND1
chr194541185045411885+CDS4.89433400.00000HepG2SND1
chr194541244145412461+CDS3.8691586.41218HepG2LARP4
chr194541183545411925+CDS4.5430237.27113K562SND1
chr194541115345411203+CDS4.0392131.87507K562SND1
chr194541101645411025+CDS,intron-Proximal4.03650400.00000HepG2DDX3X
chr194541230545412358+CDS5.27364400.00000HepG2RPS3
chr194541225945412265+CDS5.66691400.00000HepG2SND1
chr194541241045412465+CDS4.98695400.00000HepG2RPS3
chr194541181545411923+CDS3.2202626.42243HepG2FTO
chr194541112345411153+CDS4.3774924.26445K562SND1
chr194541233945412350+CDS4.1252966.64346HepG2LARP4
chr194541224245412371+CDS6.2526616.35794K562PABPC4
chr194541198945411996+CDS5.21251400.00000HepG2SND1
chr194541224545412258+CDS6.01867400.00000HepG2SND1
chr194541201345412037+CDS5.22419400.00000HepG2SND1
chr194541112545411151+CDS5.26077400.00000HepG2RPS3
chr194540990945409924+CDS4.37592400.00000HepG2DDX3X
chr194541103145411096+CDS4.216288.14875K562LIN28B
chr194541230945412318+CDS5.61725400.00000HepG2SND1
chr194541240945412416+CDS5.52638400.00000HepG2SND1
chr194541102545411089+CDS3.79267400.00000HepG2DDX3X
chr194541191845411974+CDS3.9733858.76404HepG2NOL12
chr194541101645411053+CDS,intron-Proximal5.867218.39621K562DDX3X
chr194541199645412013+CDS5.28060400.00000HepG2SND1
chr194541198245411989+CDS5.11316400.00000HepG2SND1
chr194541235245412373+CDS5.48995400.00000HepG2SND1
chr194540990245409924+CDS3.0022251.99848HepG2LARP4
chr194540990445409925+CDS,intron-Proximal5.018138.96385K562DDX3X
chr194541215545412185+CDS4.4730714.67867K562SND1
chr194541243745412471+CDS4.7936514.60240K562LIN28B
chr194541246245412465+CDS5.20593400.00000HepG2SND1
chr194541241445412478+CDS6.2770127.51042K562SND1
chr194541205645412198+CDS3.1192150.08097HepG2NOL12
chr194541215745412164+CDS5.40288400.00000HepG2SND1
chr194541229945412309+CDS5.35598400.00000HepG2SND1
chr194541112845411166+CDS3.7166177.79102HepG2LARP4
chr194541102545411065+CDS3.3899077.09452HepG2LARP4
chr194541230545412339+CDS4.43327400.00000HepG2LARP4
chr194541192545412038+CDS4.5663058.05394K562SND1
chr194541221445412262+CDS4.80492400.00000HepG2RPS3
chr194541185045411894+CDS4.610163.12173K562ZNF800
chr194541114945411181+CDS4.56241400.00000HepG2SND1
chr194541238645412437+CDS5.0436616.79818K562LIN28B
chr194541218645412215+CDS6.08592400.00000HepG2SND1
chr194541228045412299+CDS5.75534400.00000HepG2SND1
chr194541206645412129+CDS4.52211400.00000HepG2RPS3
chr194541188545411891+CDS5.07466400.00000HepG2SND1
chr194541216345412255+CDS3.59117400.00000HepG2LARP4
chr194541113545411149+CDS4.24206400.00000HepG2SND1
chr194541217345412204+CDS3.5788016.74069HepG2PCBP1
chr194541212945412162+CDS4.93784400.00000HepG2RPS3
chr194541192845411937+CDS4.92152400.00000HepG2SND1
chr194541205945412063+CDS4.69634400.00000HepG2SND1
chr194541208645412135+CDS5.47045400.00000HepG2SND1
chr194541189145411895+CDS5.09496400.00000HepG2SND1
chr194541246145412483+CDS4.0723783.61654HepG2LARP4
chr194541112345411190+CDS3.24304400.00000HepG2DDX3X
chr194541104345411117+CDS5.04658400.00000HepG2RPS3
chr194541199345412048+CDS3.2948719.12576HepG2NOL12
chr194541175245411835+CDS,intron-Proximal4.2192713.30484HepG2AQR
chr194541118145411193+CDS4.81950400.00000HepG2SND1
chr194541226945412342+CDS3.1964622.40126HepG2PCBP1
chr194541195145411979+CDS5.42933400.00000HepG2RPS3
chr194541237145412393+CDS4.6665167.13551HepG2LARP4
chr194541117945411186+CDS3.4660430.87341HepG2LARP4
chr194541193245411972+CDS3.6098966.25061HepG2LARP4
chr194541204545412059+CDS5.08172400.00000HepG2SND1
chr194541235045412371+CDS4.4766365.96082HepG2LARP4
chr194541244145412453+CDS5.42593400.00000HepG2SND1
chr194541191245411928+CDS3.1756229.06997HepG2G3BP1
chr194541237345412392+CDS5.34428400.00000HepG2SND1
chr194541233245412348+CDS5.39402400.00000HepG2SND1
chr194541241045412433+CDS3.6188832.20266HepG2LIN28B
chr194541230545412364+CDS3.1325124.39867HepG2SDAD1
chr194541194745411975+CDS5.43331400.00000HepG2SND1
chr194541248445412497+CDS4.0228374.92614HepG2LARP4
chr194541246545412490+CDS5.18233400.00000HepG2RPS3
chr194541221145412259+CDS4.4160811.52681K562SND1
chr194541218545412211+CDS5.4687117.02594K562SND1
chr194541226545412280+CDS5.86145400.00000HepG2SND1
chr194541231845412332+CDS5.74597400.00000HepG2SND1
chr194541239345412415+CDS4.2435770.26051HepG2LARP4
chr194541243345412482+CDS3.4154434.42614HepG2LIN28B
chr194541191045411920+CDS3.5947840.68275HepG2LARP4
chr194541181745411920+CDS3.627668.95271K562PUM1
chr194541208645412130+CDS3.5563721.57217HepG2PCBP1
chr194541101745411022+CDS5.05863400.00000HepG2RPS3
chr194540988545409909+CDS4.06371400.00000HepG2DDX3X
chr194541220445412259+CDS3.1766531.03293HepG2PCBP1
chr194541226545412356+CDS5.0442431.93371K562SND1
chr194541219245412214+CDS5.10391400.00000HepG2RPS3
chr194541241645412441+CDS5.59256400.00000HepG2SND1
chr194541200545412043+CDS5.13941400.00000HepG2RPS3
chr194540991645409924+CDS5.33526400.00000HepG2RPS3
chr194541225545412275+CDS4.30646400.00000HepG2LARP4
chr194541113045411189+CDS3.0100744.25552HepG2NOL12
chr194541120245411246+CDS,intron-Proximal4.7654010.73647HepG2AQR
chr194541181245411835+CDS4.3456514.15185K562SND1
chr194541183745411923+CDS3.4450553.05355HepG2SDAD1
chr194541113745411185+CDS3.2024225.36278HepG2SDAD1
chr194541193745411947+CDS5.14496400.00000HepG2SND1
chr194541230045412358+CDS3.4068954.36452HepG2NOL12
chr194541203845412137+CDS4.3434345.88233K562SND1
chr194541246545412494+CDS5.03951400.00000HepG2SND1
chr194541206345412078+CDS4.85096400.00000HepG2SND1
chr194541193645411987+CDS3.1105719.12080HepG2SDAD1
chr194541213745412155+CDS3.608699.73703K562SND1
chr194541115145411171+CDS5.46286400.00000HepG2RPS3
chr194541183545411910+CDS3.65823400.00000HepG2LARP4
chr194541102245411043+CDS4.85762400.00000HepG2RPS3
chr194541187545411925+CDS5.16607400.00000HepG2RPS3
chr194541101645411083+CDS,intron-Proximal3.1519024.61506HepG2SDAD1
chr194541183745411918+CDS3.0267049.53010HepG2NOL12
chr194541186945411925+CDS3.1491429.02159HepG2PCBP1
chr194541192645411951+CDS5.27561400.00000HepG2RPS3
chr194541183945411875+CDS4.98827400.00000HepG2RPS3
chr194541108945411110+CDS3.3508744.75928HepG2DDX3X
chr194541207845412086+CDS5.16691400.00000HepG2SND1
chr194541117145411202+CDS5.36247400.00000HepG2RPS3
chr194541239245412406+CDS5.41940400.00000HepG2SND1
chr194541226245412305+CDS5.18058400.00000HepG2RPS3
chr194541227545412302+CDS4.45005400.00000HepG2LARP4
chr194540990745409960+CDS,intron-Proximal3.326249.25586HepG2AQR
chr194541221545412243+CDS5.90057400.00000HepG2SND1
chr194541213545412157+CDS5.36685400.00000HepG2SND1
chr194541193245411969+CDS4.0043418.90665HepG2PCBP1
chr194541216445412186+CDS5.57278400.00000HepG2SND1
chr194541120345411209+CDS3.250746.54315K562SND1
chr194540992145409924+CDS3.0890041.99371HepG2GRWD1
chr194540990445409924+CDS3.2519119.54452HepG2SDAD1
chr194541241545412441+CDS4.0249683.05714HepG2LARP4
chr194541178945411799+CDS,intron-Proximal3.897238.92387K562SND1
chr194541197545411981+CDS5.31659400.00000HepG2SND1
chr194541136045411437+intron-Distal4.3916411.64729HepG2PTBP1
chr194541134545411435+intron-Distal5.216933.42734K562PTBP1
chr194540923545409294+intron-Distal,intron-Proximal3.203527.06076HepG2PRPF4
chr194541096145411004+intron-Proximal3.922753.74254HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for APOE is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for APOE is not available on ENCORE database.

  • 147 RBPs can affect the levels of APOE.  








The Knockdown/knockout RNA-Seq assay for APOE is not available on ENCORE database.





147 RBPs can affect the gene expression of APOE :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
APOEENSG00000130203.532807.8722016694.179400.9746020.4225018.31140HepG2ABCF1
APOEENSG00000130203.55417.509003490.470500.634105.454604.12070HepG2ADAR
APOEENSG00000130203.56942.9665017117.19520-1.301806.607805.82490HepG2AKAP1
APOEENSG00000130203.519921.0010012368.027500.687608.907307.15260HepG2AKAP8
APOEENSG00000130203.518233.0262013968.311800.384309.998108.65060HepG2AKAP8L
APOEENSG00000130203.517045.1546012900.525600.401802.012601.41000HepG2AUH
APOEENSG00000130203.510878.144604870.650001.159104.767903.53670HepG2BCCIP
APOEENSG00000130203.58303.786404231.198700.9726010.536808.92800HepG2BCLAF1
APOEENSG00000130203.516776.651408187.319701.0349010.095809.04600HepG2BOP1
APOEENSG00000130203.515825.9899012503.294500.339902.822601.57720HepG2BUD13
APOEENSG00000130203.517817.9625012958.880800.459303.590802.46520HepG2CCAR1
APOEENSG00000130203.523731.8472013454.981500.8186010.078208.68240HepG2CIRBP
APOEENSG00000130203.511820.8156013899.79300-0.233705.753004.85710HepG2CKAP4
APOEENSG00000130203.518221.604307515.933601.2775025.6535023.82750HepG2CPSF6
APOEENSG00000130203.517778.8851013742.523500.371402.781401.67420HepG2CPSF7
APOEENSG00000130203.55711.469903579.599900.674004.713303.38810HepG2YBX3
APOEENSG00000130203.54839.362103007.114000.686304.560903.21990HepG2CSTF2
APOEENSG00000130203.58711.611306194.450100.4919010.480109.38500HepG2CELF1
APOEENSG00000130203.58792.588906660.496700.4006014.0753012.62120HepG2DAZAP1
APOEENSG00000130203.514868.9773012858.589500.209504.204303.20030HepG2DDX19B
APOEENSG00000130203.510826.457506635.583800.706203.894903.10390HepG2DDX21
APOEENSG00000130203.519310.0743015706.739100.297902.919701.58960HepG2DDX47
APOEENSG00000130203.58265.439904789.389400.787104.631103.65790HepG2DDX55
APOEENSG00000130203.515641.3162010382.938600.591002.868901.83900HepG2DDX5
APOEENSG00000130203.535103.5227014089.866401.316906.844005.90740HepG2DDX6
APOEENSG00000130203.56267.897303389.836200.886707.454305.91530HepG2DHX30
APOEENSG00000130203.522039.0775013301.943200.7283035.8343034.12030HepG2DKC1
APOEENSG00000130203.59997.961603514.448501.5082016.1342014.57150HepG2DNAJC21
APOEENSG00000130203.55357.808203484.069400.620805.222104.37160HepG2DNAJC2
APOEENSG00000130203.523176.4917013537.863200.775604.128803.41310HepG2EIF2S1
APOEENSG00000130203.57873.4014014569.76190-0.887902.609301.93940HepG2EIF4B
APOEENSG00000130203.514501.196306294.625601.2039020.2904018.24870HepG2EIF4G2
APOEENSG00000130203.519082.3306014812.330200.365308.985408.00590HepG2ETF1
APOEENSG00000130203.512172.0178016855.97190-0.469703.620202.74770HepG2FIP1L1
APOEENSG00000130203.56317.392003985.809000.664403.407702.00540HepG2FKBP4
APOEENSG00000130203.524194.742507529.797901.683905.945604.45940HepG2FTO
APOEENSG00000130203.56363.0644018243.58700-1.5196066.9915063.68240HepG2FUBP3
APOEENSG00000130203.58437.445804842.792700.800904.943003.57890HepG2GNB2L1
APOEENSG00000130203.524090.500008518.603201.499705.128804.27480HepG2GPKOW
APOEENSG00000130203.58535.121104218.906201.016407.130804.86330HepG2HNRNPA0
APOEENSG00000130203.59378.300903548.125101.402207.741806.74310HepG2HNRNPA1
APOEENSG00000130203.57140.068704119.063400.793503.736602.10170HepG2HNRNPAB
APOEENSG00000130203.59125.192403946.850501.209101.959601.36500HepG2HNRNPC
APOEENSG00000130203.515516.964406800.094201.1901039.2476037.10760HepG2HNRNPF
APOEENSG00000130203.512127.078806067.185100.9990017.7532016.18180HepG2HNRNPL
APOEENSG00000130203.518212.791408129.577001.1636018.9962017.56810HepG2HNRNPLL
APOEENSG00000130203.59380.5496011626.72900-0.309702.853101.88730HepG2HNRNPM
APOEENSG00000130203.57902.126903920.740301.0110032.4081030.53340HepG2HNRNPU
APOEENSG00000130203.517037.752406696.269001.347208.365607.16970HepG2IGF2BP1
APOEENSG00000130203.521640.6904014232.555400.604504.992804.11040HepG2IGF2BP2
APOEENSG00000130203.56532.742704004.869200.705806.729405.63580HepG2ILF2
APOEENSG00000130203.59289.171504856.899700.935403.646402.09970HepG2ILF3
APOEENSG00000130203.59199.649304753.162900.952604.186402.66740HepG2KHDRBS1
APOEENSG00000130203.514378.4773012709.215900.177903.663902.49170HepG2KIF1C
APOEENSG00000130203.526488.4058013690.652400.9521013.7031011.88850HepG2LARP4
APOEENSG00000130203.525513.1921015107.165400.755906.782505.76940HepG2MAGOH
APOEENSG00000130203.516455.596208293.938500.9883011.426909.44920HepG2MTPAP
APOEENSG00000130203.57986.888404291.315200.896106.515504.32880HepG2NIP7
APOEENSG00000130203.59430.492406604.537900.5138011.209509.71490HepG2NOL12
APOEENSG00000130203.515524.617504400.568601.818707.931606.05670HepG2NONO
APOEENSG00000130203.519087.775707209.363601.4046030.7826028.72480HepG2NSUN2
APOEENSG00000130203.59085.495904554.624100.996106.424905.03640HepG2PABPC1
APOEENSG00000130203.55082.349303880.589600.389103.774802.80320HepG2PARN
APOEENSG00000130203.59487.6418015272.10550-0.686807.714906.78220HepG2PCBP1
APOEENSG00000130203.59523.167703496.949101.4452025.5137023.44500HepG2PPIL4
APOEENSG00000130203.511063.927008211.902000.430002.664501.90390HepG2PRPF4
APOEENSG00000130203.515581.595106304.625301.3053049.1116047.00730HepG2PUF60
APOEENSG00000130203.510453.194206692.656600.6432038.8625037.16540HepG2PUM1
APOEENSG00000130203.513858.416606687.756501.051105.631504.68820HepG2PUM2
APOEENSG00000130203.59673.9545016828.77890-0.798805.425704.59340HepG2QKI
APOEENSG00000130203.521201.3100012380.200100.7760031.0711029.70390HepG2RBM22
APOEENSG00000130203.59589.518405723.810300.744405.673804.23780HepG2RBM27
APOEENSG00000130203.511921.7595016109.73150-0.434302.764302.14810HepG2RECQL
APOEENSG00000130203.523648.260807323.608701.6910011.3937010.17200HepG2RPLP0
APOEENSG00000130203.513881.918206395.330601.1180010.603209.49530HepG2RPS19
APOEENSG00000130203.512182.071005278.271901.2065015.3518013.58120HepG2RPS2
APOEENSG00000130203.514265.315905008.345001.5100018.0073016.06900HepG2RPS3A
APOEENSG00000130203.58099.324905388.614300.587803.193402.03310HepG2RPS5
APOEENSG00000130203.56839.247503491.464500.9699024.9759023.30720HepG2SAFB2
APOEENSG00000130203.527235.0857017127.178400.669102.813002.13380HepG2SF3A3
APOEENSG00000130203.512120.2925016178.10730-0.416602.963802.35570HepG2SF3B4
APOEENSG00000130203.514089.847306045.190701.2207070.4177068.00700HepG2SLBP
APOEENSG00000130203.57188.825904071.421600.8201020.7108019.19960HepG2SMN1
APOEENSG00000130203.510626.9383013982.68540-0.395908.171607.43660HepG2SRFBP1
APOEENSG00000130203.56672.9097016887.38980-1.3396020.1165019.08830HepG2SRSF1
APOEENSG00000130203.518812.199506224.921201.59540154.91900151.37830HepG2SRSF5
APOEENSG00000130203.515518.446506680.461701.2159010.323709.12690HepG2SRSF7
APOEENSG00000130203.517184.0336013739.607700.322603.692503.07530HepG2SRSF9
APOEENSG00000130203.523746.4505012139.766200.9679067.0748065.40840HepG2SSB
APOEENSG00000130203.57240.357004359.100400.731903.124001.95080HepG2STIP1
APOEENSG00000130203.512427.329507079.431500.8117046.0451044.05190HepG2SUCLG1
APOEENSG00000130203.510236.9720013581.47800-0.407902.944801.57340HepG2SUGP2
APOEENSG00000130203.515643.2992011377.644600.459206.844105.41040HepG2SUPT6H
APOEENSG00000130203.525078.931004766.939002.3952089.8161087.13340HepG2SUPV3L1
APOEENSG00000130203.56040.4256015181.67560-1.3296013.3456012.25230HepG2TAF15
APOEENSG00000130203.517402.898707927.249201.1343013.8560012.43580HepG2TARDBP
APOEENSG00000130203.511490.009503194.609801.8466031.5993029.11210HepG2TFIP11
APOEENSG00000130203.59074.8755013947.09980-0.620003.479402.54610HepG2TIA1
APOEENSG00000130203.513670.495003808.916401.8435044.1579042.60680HepG2TIAL1
APOEENSG00000130203.510426.137903843.840601.43950103.33070100.52640HepG2TRIM56
APOEENSG00000130203.516287.735106159.382001.402805.622204.32310HepG2TUFM
APOEENSG00000130203.516686.040206519.628701.355702.393001.61820HepG2UBE2L3
APOEENSG00000130203.55268.751502815.414300.904008.371007.05160HepG2UCHL5
APOEENSG00000130203.527233.8149015189.214100.8423023.5181021.87460HepG2UPF1
APOEENSG00000130203.511528.954304362.884201.401803.315202.21280HepG2UPF2
APOEENSG00000130203.519622.7282014664.550500.4201012.4901011.35830HepG2UTP3
APOEENSG00000130203.510134.568104486.375401.175609.722007.69520HepG2XPO5
APOEENSG00000130203.514936.518304692.553601.6703049.3944046.73180HepG2XRN2
APOEENSG00000130203.511905.980908103.490200.555006.790505.81430HepG2ZC3H8
APOEENSG00000130203.528616.2305016705.192100.7764066.4018064.65460HepG2ZNF622
APOEENSG00000130203.5101.00700230.86680-1.192603.390502.06710K562AARS
APOEENSG00000130203.5675.59850476.464000.503702.834601.59230K562ABCF1
APOEENSG00000130203.5405.65080202.785101.000204.499602.27730K562ADAR
APOEENSG00000130203.51334.81810559.520401.2543039.8133037.71670K562AGGF1
APOEENSG00000130203.51163.73740614.885100.9203015.0926012.36650K562AKAP8
APOEENSG00000130203.51381.23440582.220301.246208.634907.41470K562AKAP8L
APOEENSG00000130203.5756.47170610.915600.308202.622101.73430K562ATP5C1
APOEENSG00000130203.5857.34470640.294800.421003.577001.32450K562AUH
APOEENSG00000130203.5428.52590201.517601.088402.860401.52010K562BCCIP
APOEENSG00000130203.5318.26500194.741300.708605.047903.73570K562BCLAF1
APOEENSG00000130203.5987.31720668.612200.562205.197103.53950K562CCDC124
APOEENSG00000130203.5949.90000623.762000.606703.124501.98500K562CNOT7
APOEENSG00000130203.5596.50980391.552900.607204.846703.81310K562CPSF6
APOEENSG00000130203.5346.22750147.740301.228603.808902.54280K562CSTF2
APOEENSG00000130203.5647.748901002.18630-0.629606.676505.17810K562CELF1
APOEENSG00000130203.51026.65840656.471700.645107.338304.97070K562DDX19B
APOEENSG00000130203.5989.02490642.956500.621208.928206.75100K562DDX21
APOEENSG00000130203.5772.64910643.328000.264202.041501.46770K562DDX47
APOEENSG00000130203.51047.23010477.289901.1335025.7274021.84110K562DDX6
APOEENSG00000130203.51059.39580626.423200.7579013.9557011.66190K562DKC1
APOEENSG00000130203.5756.28200213.545301.824306.133004.15390K562DNAJC21
APOEENSG00000130203.5242.27030390.05460-0.687102.883102.15200K562EIF2S2
APOEENSG00000130203.5435.47160187.074601.2189010.159408.00380K562EIF3D
APOEENSG00000130203.5246.27530491.82060-0.9979010.808809.16260K562EIF4A3
APOEENSG00000130203.51087.16410814.860400.415804.022102.89150K562EIF4G2
APOEENSG00000130203.5731.74840263.944901.4710027.9964024.38670K562EXOSC5
APOEENSG00000130203.566.28700219.52950-1.727604.917503.34170K562FKBP4
APOEENSG00000130203.5484.01370337.683500.519303.198902.21070K562FTO
APOEENSG00000130203.5163.80060511.46850-1.6427028.7001026.88460K562FXR1
APOEENSG00000130203.511.06680106.83500-3.2711016.0008013.95880K562G3BP2
APOEENSG00000130203.5431.92680693.67980-0.683508.242006.35860K562GLRX3
APOEENSG00000130203.5840.93620373.834401.169509.018307.57560K562GPKOW
APOEENSG00000130203.51199.64720519.681201.2068014.6967012.91610K562GRSF1
APOEENSG00000130203.5141.61870252.29910-0.833102.350801.79460K562HNRNPC
APOEENSG00000130203.51557.49040581.434701.421403.815802.54880K562HNRNPL
APOEENSG00000130203.5524.55450281.785900.896407.680406.00530K562HNRNPM
APOEENSG00000130203.5658.42790464.388200.503603.695602.78000K562HSPD1
APOEENSG00000130203.5352.89850200.461300.815803.733002.01210K562KHDRBS1
APOEENSG00000130203.5947.23480591.457200.679307.774605.60540K562MAK16
APOEENSG00000130203.51044.90640469.490801.154107.900004.53540K562NFX1
APOEENSG00000130203.5356.51640891.41690-1.3221023.0123019.24980K562NOL12
APOEENSG00000130203.5731.65400172.472002.0847015.7879012.65210K562NONO
APOEENSG00000130203.51086.56870810.333400.423104.574803.64390K562NSUN2
APOEENSG00000130203.51331.14150599.251401.1513010.606408.22120K562PABPC1
APOEENSG00000130203.5411.18740199.132701.046006.358403.15640K562PARN
APOEENSG00000130203.5100.01310185.31580-0.889803.226001.76600K562PCBP1
APOEENSG00000130203.5287.39440165.679500.794504.200601.88220K562PES1
APOEENSG00000130203.5151.64660257.51410-0.763904.827603.76930K562POLR2G
APOEENSG00000130203.5554.37940388.910300.511303.702102.73200K562PPIG
APOEENSG00000130203.5182.24690504.35760-1.4686010.886507.81630K562PRPF6
APOEENSG00000130203.5474.55950226.251301.068607.663006.01600K562PSIP1
APOEENSG00000130203.5112.38110184.11910-0.712202.615001.96650K562PTBP1
APOEENSG00000130203.51401.02380926.524800.596508.570706.85470K562PUM2
APOEENSG00000130203.5892.57930577.303000.628606.040005.27540K562PUS1
APOEENSG00000130203.513.63280101.91400-2.9022010.533607.78260K562RAVER1
APOEENSG00000130203.5947.48860562.577500.752007.984907.00880K562RBM15
APOEENSG00000130203.5512.58940206.611301.3108017.2692014.80130K562RCC2
APOEENSG00000130203.5162.94010111.001200.553702.146001.39400K562SF3B4
APOEENSG00000130203.582.99910162.01480-0.965004.500202.24370K562SLTM
APOEENSG00000130203.555.74470145.21130-1.381206.977304.10260K562SND1
APOEENSG00000130203.5379.50620169.957601.158804.759902.56270K562SRP68
APOEENSG00000130203.5381.80810819.19910-1.1014024.0187021.71400K562SRPK2
APOEENSG00000130203.5862.54220574.314900.586704.272002.92050K562SRSF4
APOEENSG00000130203.5392.32970170.536601.201909.749307.63690K562SRSF5
APOEENSG00000130203.5774.29450573.734000.432404.416702.91680K562SRSF7
APOEENSG00000130203.5248.02490449.40810-0.857504.928403.07180K562SSRP1
APOEENSG00000130203.5276.54680411.01330-0.571703.316201.91540K562STAU1
APOEENSG00000130203.5327.66500176.200500.894905.401904.19910K562TIA1
APOEENSG00000130203.5363.37500217.593300.739704.481003.26860K562TIAL1
APOEENSG00000130203.548.00360106.88260-1.154804.618003.58660K562U2AF2
APOEENSG00000130203.5399.75740174.252701.1978010.521708.49010K562UCHL5
APOEENSG00000130203.51408.27680859.213700.7127011.9076010.54680K562UPF1
APOEENSG00000130203.5977.44390491.190400.9926016.9112013.57440K562UPF2
APOEENSG00000130203.51291.41080585.426001.141308.808006.21010K562UTP18
APOEENSG00000130203.5290.07280489.25290-0.754204.508202.96650K562UTP3
APOEENSG00000130203.5423.75270764.52460-0.8513015.4365013.65580K562WDR43
APOEENSG00000130203.5264.65140475.15020-0.844304.246302.17320K562XRCC6
APOEENSG00000130203.5470.89960177.533301.407208.208305.83010K562XRN2
APOEENSG00000130203.51037.36050608.856100.768604.808503.62410K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for APOE is not available on ENCORE database.





4 RBPs can affect the splicing of APOE :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A5SSAPOEENSG00000130203.5chr19+4540906845409301454090684540918045409858454099240.061000.000010.01245longerHepG2UCHL5
MXEAPOEENSG00000130203.5chr19+4540985845409924454110164541120945409010454090984541178945412650-0.084000.000780.038442includedHepG2BCCIP
MXEAPOEENSG00000130203.5chr19+45409858454099244541101645411209454090104540909845411789454126500.082000.000000.000001includedHepG2SFPQ
MXEAPOEENSG00000130203.5chr19+45409858454099244541101645411209454090104540909845411789454126500.069000.000000.000001includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for APOE is not avaliable on ENCORE database.