SMPDL3A

General Information

Gene Name       : SMPDL3A
Gene ID             : ENSG00000172594.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SMPDL3A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SMPDL3AENSG00000172594.120.160.060.11ENCSR000AEF
HepG2SMPDL3AENSG00000172594.123.436.995.21ENCSR985KAT
K562SMPDL3AENSG00000172594.120.310.430.37ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SMPDL3A is not avaliable on ENCORE database.



Proteins bound to RNA
  • SMPDL3A RNA is bound by 1 proteins.  







eCLIP assay for SMPDL3A is not avaliable on ENCORE database.





1 proteins are bound to SMPDL3A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6123110401123110489+5'-UTR4.739015.48791HepG2DDX3X
chr6123110489123110578+5'-UTR,CDS3.703475.65659HepG2DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SMPDL3A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SMPDL3A is not available on ENCORE database.

  • 123 RBPs can affect the levels of SMPDL3A.  








The Knockdown/knockout RNA-Seq assay for SMPDL3A is not available on ENCORE database.





123 RBPs can affect the gene expression of SMPDL3A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SMPDL3AENSG00000172594.8490.257201157.77070-1.2397016.3319015.14860HepG2AKAP1
SMPDL3AENSG00000172594.8890.77040528.592600.752807.159005.01830HepG2ATP5C1
SMPDL3AENSG00000172594.8854.62520435.663200.9720019.2194017.71490HepG2AUH
SMPDL3AENSG00000172594.8431.42650184.235701.2275011.444509.78030HepG2BCLAF1
SMPDL3AENSG00000172594.82052.13630367.184802.4824093.6720091.35660HepG2BOP1
SMPDL3AENSG00000172594.81286.44750417.354801.6239046.3644044.01180HepG2CALR
SMPDL3AENSG00000172594.81317.99430910.132800.534104.858103.84900HepG2CIRBP
SMPDL3AENSG00000172594.81341.54990565.222701.246905.903504.78440HepG2CNOT7
SMPDL3AENSG00000172594.81377.74220337.100902.0310045.9081043.60000HepG2CPSF6
SMPDL3AENSG00000172594.8817.64890482.409000.761108.536206.70460HepG2CPSF7
SMPDL3AENSG00000172594.8760.19670391.733000.9564016.0169014.72030HepG2CELF1
SMPDL3AENSG00000172594.8896.67110421.257801.0898026.7184024.85660HepG2DAZAP1
SMPDL3AENSG00000172594.8437.61620264.876100.724206.383204.70530HepG2DDX1
SMPDL3AENSG00000172594.8481.02220304.055900.661705.020904.13540HepG2DDX21
SMPDL3AENSG00000172594.8467.52640297.558800.651805.076203.83160HepG2DDX24
SMPDL3AENSG00000172594.8319.22740195.049100.710603.752202.28540HepG2DDX27
SMPDL3AENSG00000172594.8322.09770157.948801.027907.876605.72080HepG2DDX28
SMPDL3AENSG00000172594.83325.431301109.079601.5841039.1406037.07050HepG2DDX3X
SMPDL3AENSG00000172594.81361.81150761.233200.839006.742304.79620HepG2DDX47
SMPDL3AENSG00000172594.8488.34580208.411001.2284011.4581010.01370HepG2DDX55
SMPDL3AENSG00000172594.8976.63940382.801101.351104.538203.29630HepG2DDX59
SMPDL3AENSG00000172594.81046.58330552.101600.9226012.5984010.63490HepG2DDX5
SMPDL3AENSG00000172594.8567.93380952.66830-0.746306.573405.65280HepG2DDX6
SMPDL3AENSG00000172594.8654.29540250.505201.3850021.9119019.65430HepG2DHX30
SMPDL3AENSG00000172594.8493.20090392.667200.328802.102701.49970HepG2DKC1
SMPDL3AENSG00000172594.8945.91290259.729301.8646055.7400053.15540HepG2DNAJC21
SMPDL3AENSG00000172594.8335.66250257.421000.382802.320901.71280HepG2DNAJC2
SMPDL3AENSG00000172594.8457.46600280.005000.708102.845501.72210HepG2AGO1
SMPDL3AENSG00000172594.81602.42750915.876800.806909.956808.87260HepG2EIF2S1
SMPDL3AENSG00000172594.8675.053501012.17740-0.584404.412103.60860HepG2EIF4A3
SMPDL3AENSG00000172594.8448.73350985.44730-1.1349011.331709.98510HepG2EIF4B
SMPDL3AENSG00000172594.8564.20780415.554700.441103.347902.44270HepG2EIF4G1
SMPDL3AENSG00000172594.8923.27840398.082401.213607.263405.97250HepG2EIF4G2
SMPDL3AENSG00000172594.8720.17490500.149800.525905.982305.15460HepG2ETF1
SMPDL3AENSG00000172594.8211.51450401.08030-0.923108.577607.12340HepG2EWSR1
SMPDL3AENSG00000172594.8452.21670289.763200.642004.839003.39020HepG2FASTKD2
SMPDL3AENSG00000172594.8335.39320591.57870-0.818706.144505.04130HepG2FIP1L1
SMPDL3AENSG00000172594.8435.67130173.492701.3283013.6629011.27680HepG2FKBP4
SMPDL3AENSG00000172594.81428.40350337.667802.0806018.3383015.88780HepG2FTO
SMPDL3AENSG00000172594.8364.09020646.63940-0.828708.985407.60990HepG2FUBP3
SMPDL3AENSG00000172594.8274.448301021.16620-1.8956037.8397035.64880HepG2FXR1
SMPDL3AENSG00000172594.8647.802601005.65050-0.634505.910904.59820HepG2G3BP2
SMPDL3AENSG00000172594.8646.19000382.144500.757706.066405.14440HepG2GPKOW
SMPDL3AENSG00000172594.8319.29420523.18310-0.712404.178502.81370HepG2GRSF1
SMPDL3AENSG00000172594.8782.37140381.921701.034507.272004.94110HepG2HLTF
SMPDL3AENSG00000172594.8715.20070477.693700.582203.470501.92400HepG2HNRNPA0
SMPDL3AENSG00000172594.8188.00950262.21740-0.480002.133701.55910HepG2HNRNPA1
SMPDL3AENSG00000172594.8578.95990387.124500.580602.706001.77920HepG2HNRNPA2B1
SMPDL3AENSG00000172594.8732.57400489.575800.581303.587901.84210HepG2HNRNPD
SMPDL3AENSG00000172594.8503.83520201.349301.3232022.3144020.54690HepG2HNRNPF
SMPDL3AENSG00000172594.8172.94700959.15370-2.4714058.8173055.95890HepG2HNRNPK
SMPDL3AENSG00000172594.8503.28170383.748400.391102.923802.23260HepG2HNRNPL
SMPDL3AENSG00000172594.83183.66710364.686303.12590136.34330133.23550HepG2HNRNPLL
SMPDL3AENSG00000172594.8163.44430408.12170-1.3202015.1885013.26400HepG2HNRNPM
SMPDL3AENSG00000172594.8630.56760198.273401.6691021.5094019.71540HepG2IGF2BP1
SMPDL3AENSG00000172594.8661.02620295.956101.1592025.4022023.45790HepG2ILF2
SMPDL3AENSG00000172594.8233.50450329.35530-0.496202.547901.46110HepG2LARP7
SMPDL3AENSG00000172594.8637.159501021.52230-0.681006.320405.33740HepG2MAGOH
SMPDL3AENSG00000172594.8706.889701027.25240-0.539203.886503.15010HepG2MATR3
SMPDL3AENSG00000172594.8927.57170478.718100.9542013.5058011.86220HepG2MSI2
SMPDL3AENSG00000172594.8829.08290371.901201.156503.003901.98960HepG2MTPAP
SMPDL3AENSG00000172594.8611.16480401.997400.604302.663001.47130HepG2NAA15
SMPDL3AENSG00000172594.8723.57820323.353701.1619014.7875013.20760HepG2NSUN2
SMPDL3AENSG00000172594.81063.81300773.987400.458803.275701.53630HepG2NUP35
SMPDL3AENSG00000172594.8888.28370516.532000.782104.703703.52320HepG2PABPC1
SMPDL3AENSG00000172594.81749.41940936.441700.9015012.3966010.89780HepG2PABPC4
SMPDL3AENSG00000172594.8483.89880316.013700.614603.592701.67730HepG2PHF6
SMPDL3AENSG00000172594.8348.69650258.421800.432102.585901.87220HepG2PPIL4
SMPDL3AENSG00000172594.8259.58560396.78620-0.612202.886501.64260HepG2PRPF6
SMPDL3AENSG00000172594.8501.30010958.56980-0.9352017.9086016.74450HepG2PTBP1
SMPDL3AENSG00000172594.8295.04520398.73270-0.434502.469301.90220HepG2PUF60
SMPDL3AENSG00000172594.8709.86330423.256600.7459011.9358010.88630HepG2PUM1
SMPDL3AENSG00000172594.81298.00880422.957301.6176045.7494043.33960HepG2PUM2
SMPDL3AENSG00000172594.8754.21360418.042100.8512014.9324013.70230HepG2PUS1
SMPDL3AENSG00000172594.8790.795101038.22810-0.392703.873603.15140HepG2QKI
SMPDL3AENSG00000172594.8555.25240364.274100.608002.636401.94780HepG2RAVER1
SMPDL3AENSG00000172594.8641.34100418.043100.617305.294704.63570HepG2RBM22
SMPDL3AENSG00000172594.8759.85370942.23100-0.310402.284001.66600HepG2RBM25
SMPDL3AENSG00000172594.8830.95670545.824600.606203.789802.00380HepG2RBM47
SMPDL3AENSG00000172594.8169.92370322.50270-0.924404.828203.41770HepG2RCC2
SMPDL3AENSG00000172594.8263.139001066.82470-2.0194067.6873065.88770HepG2NELFE
SMPDL3AENSG00000172594.8346.15300993.55030-1.5212042.8158040.96870HepG2RECQL
SMPDL3AENSG00000172594.8704.71090216.874901.7001030.1895028.46340HepG2RPLP0
SMPDL3AENSG00000172594.81071.10830357.743401.5820019.6293017.37150HepG2RPS10
SMPDL3AENSG00000172594.8178.89790279.85270-0.645503.567002.87840HepG2RPS19
SMPDL3AENSG00000172594.8302.65130159.141900.927205.852704.75310HepG2RRP9
SMPDL3AENSG00000172594.8666.57770396.197200.750503.443401.73790HepG2RTF1
SMPDL3AENSG00000172594.8499.66380258.025200.9533013.1857011.93630HepG2SAFB2
SMPDL3AENSG00000172594.8541.67970280.901500.947306.442205.02410HepG2SERBP1
SMPDL3AENSG00000172594.8270.92700699.08530-1.3676014.5341012.92110HepG2SF3A3
SMPDL3AENSG00000172594.8628.68150360.975700.800307.763206.63440HepG2SF3B1
SMPDL3AENSG00000172594.8641.78560998.05660-0.637009.910408.89260HepG2SF3B4
SMPDL3AENSG00000172594.8571.00250382.290000.578706.206605.22210HepG2SLBP
SMPDL3AENSG00000172594.8159.31190300.90580-0.917508.351907.32840HepG2SMN1
SMPDL3AENSG00000172594.81488.96130401.645701.8902019.3969017.38240HepG2SNRNP70
SMPDL3AENSG00000172594.81190.16820472.182601.3336025.5332024.41190HepG2SRFBP1
SMPDL3AENSG00000172594.8755.152901041.72980-0.464106.262605.62170HepG2SRSF1
SMPDL3AENSG00000172594.8603.95450197.812701.6102035.1210033.20430HepG2SRSF7
SMPDL3AENSG00000172594.8603.81940409.998400.558406.037105.33480HepG2SSB
SMPDL3AENSG00000172594.8544.36680395.073900.462402.530101.34130HepG2STAU1
SMPDL3AENSG00000172594.8642.43330340.410200.916203.610902.22580HepG2SUB1
SMPDL3AENSG00000172594.8856.06720399.404801.0998017.9381015.76170HepG2SUPT6H
SMPDL3AENSG00000172594.8551.97170207.497901.4114010.122308.96400HepG2SUPV3L1
SMPDL3AENSG00000172594.8551.51160936.27740-0.7635012.2642011.21340HepG2TAF15
SMPDL3AENSG00000172594.81577.18240355.418102.1497064.2930061.68740HepG2TARDBP
SMPDL3AENSG00000172594.8286.69940139.095601.043407.262705.77910HepG2TFIP11
SMPDL3AENSG00000172594.8517.68770281.550600.878609.867909.02640HepG2TIAL1
SMPDL3AENSG00000172594.8374.11490284.047700.397202.544401.99920HepG2TRIM56
SMPDL3AENSG00000172594.8510.69720389.519100.390702.251201.46890HepG2TUFM
SMPDL3AENSG00000172594.8659.09840412.282900.676804.290303.23570HepG2UBE2L3
SMPDL3AENSG00000172594.8965.16820619.979600.6385010.630809.42300HepG2UPF1
SMPDL3AENSG00000172594.8287.25650190.078300.595602.218801.32510HepG2UPF2
SMPDL3AENSG00000172594.8436.37980598.56930-0.455903.906403.21350HepG2UTP3
SMPDL3AENSG00000172594.81067.92840508.135001.0714011.099208.94620HepG2XPO5
SMPDL3AENSG00000172594.8178.58090400.56010-1.165408.892307.10440HepG2XRCC6
SMPDL3AENSG00000172594.8694.11350322.131601.1074013.6382012.33480HepG2ZC3H8
SMPDL3AENSG00000172594.81262.35560681.862000.8885025.5480024.30910HepG2ZNF622
SMPDL3AENSG00000172594.863.6996017.883001.832604.370303.66450K562AQR
SMPDL3AENSG00000172594.835.3252012.390401.511402.184301.41550K562BOP1
SMPDL3AENSG00000172594.838.0815013.170101.531702.517101.76800K562CPSF6
SMPDL3AENSG00000172594.85.4449021.30650-1.968302.160101.45050K562EIF3G
SMPDL3AENSG00000172594.847.5041013.408901.824803.734202.73630K562FMR1
SMPDL3AENSG00000172594.834.2455011.369001.590702.446601.58900K562FTO
SMPDL3AENSG00000172594.834.1560013.740001.313701.981201.39580K562G3BP2
SMPDL3AENSG00000172594.851.5348010.743102.262002.161201.34750K562KRR1
SMPDL3AENSG00000172594.855.925107.056202.986407.490406.12270K562PCBP3
SMPDL3AENSG00000172594.843.749405.412003.014906.981305.71840K562POLR2G
SMPDL3AENSG00000172594.845.8246016.748301.452002.276001.53680K562PUF60
SMPDL3AENSG00000172594.852.9411017.828301.570102.988401.87490K562PUM1
SMPDL3AENSG00000172594.831.6174012.367601.354101.913601.31290K562SRSF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SMPDL3A is not available on ENCORE database.





14 RBPs can affect the splicing of SMPDL3A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESMPDL3AENSG00000172594.8chr6+123122454123122551123117968123118113123124808123124978-0.310000.000000.00014excludedHepG2HNRNPK
SESMPDL3AENSG00000172594.8chr6+123116821123117035123110314123110603123117968123118113-0.232000.002380.05397excludedHepG2HNRNPK
SESMPDL3AENSG00000172594.8chr6+1231273771231275021231260531231262341231302351231308650.186000.000010.00173includedHepG2DDX59
SESMPDL3AENSG00000172594.8chr6+1231224541231225511231179681231181131231248081231249780.116000.000010.00123includedHepG2TBRG4
SESMPDL3AENSG00000172594.8chr6+1231168211231170351231103141231106031231179681231181130.207000.000000.00001includedHepG2TBRG4
SESMPDL3AENSG00000172594.8chr6+123122454123122551123117968123118113123124808123124978-0.149000.000360.03603excludedHepG2QKI
SESMPDL3AENSG00000172594.8chr6+123127377123127502123126053123126234123130235123130865-0.125000.010300.09349excludedHepG2U2AF2
SESMPDL3AENSG00000172594.8chr6+123122454123122551123117968123118113123124808123124978-0.136000.000110.06405excludedHepG2SUGP2
SESMPDL3AENSG00000172594.8chr6+123110933123111054123110314123110603123117968123118113-0.094000.001090.07484excludedHepG2DDX3X
SESMPDL3AENSG00000172594.8chr6+1231273771231275021231260531231262341231302351231308650.170000.000060.00752includedHepG2FTO
SESMPDL3AENSG00000172594.8chr6+1231224541231225511231179681231181131231248081231249780.111000.002750.08912includedHepG2MATR3
SESMPDL3AENSG00000172594.8chr6+1231224541231225511231179681231181131231248081231249780.114000.000080.00305includedHepG2SRSF1
SESMPDL3AENSG00000172594.8chr6+123127377123127502123126053123126234123130235123130865-0.185000.002320.05874excludedHepG2SF3A3
SESMPDL3AENSG00000172594.8chr6+123116854123117035123110314123110603123117968123118490-0.176000.002100.08060excludedHepG2SF3B4
SESMPDL3AENSG00000172594.8chr6+1231224541231225511231179681231181131231248081231249780.143000.000490.09514includedHepG2EIF3D
SESMPDL3AENSG00000172594.8chr6+123122454123122551123117968123118113123126053123126234-0.494000.002140.07568excludedHepG2HNRNPU
MXESMPDL3AENSG00000172594.8chr6+123122454123122551123124808123125028123117968123118113123126053123126234-0.225000.000170.029502includedHepG2SUGP2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SMPDL3A is not avaliable on ENCORE database.