SFXN2

General Information

Gene Name       : SFXN2
Gene ID             : ENSG00000156398.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SFXN2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SFXN2ENSG00000156398.1210.1513.2911.72ENCSR000AEF
HepG2SFXN2ENSG00000156398.1221.7218.3820.05ENCSR985KAT
K562SFXN2ENSG00000156398.1217.3815.9716.68ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SFXN2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SFXN2 RNA is bound by 21 proteins.  







eCLIP assay for SFXN2 is not avaliable on ENCORE database.





21 proteins are bound to SFXN2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10104492650104492704+3'-UTR,CDS,intron-Proximal5.025967.46483HepG2PRPF8
chr10104493323104493447+3'-UTR,CDS,intron-Proximal4.670875.70555K562PRPF8
chr10104495618104495675+3'-UTR,CDS,intron-Proximal3.993825.18845HepG2U2AF2
chr10104486741104486810+3'-UTR,CDS,intron-Proximal4.5757213.94155HepG2PPIG
chr10104486901104486952+3'-UTR,CDS,intron-Proximal4.456244.62947HepG2AQR
chr10104495620104495672+3'-UTR,CDS,intron-Proximal3.324264.16939HepG2PPIG
chr10104493315104493377+3'-UTR,CDS,intron-Proximal5.700667.41664HepG2EFTUD2
chr10104493314104493382+3'-UTR,CDS,intron-Proximal6.1026824.36373HepG2PRPF8
chr10104486889104486964+3'-UTR,CDS,intron-Proximal4.3765519.55694HepG2PRPF8
chr10104497357104497448+3'-UTR,CDS,intron-Proximal3.2218012.47043HepG2SF3A3
chr10104486794104486829+3'-UTR,CDS3.369303.65567HepG2BUD13
chr10104492518104492626+3'-UTR,CDS,intron-Proximal3.5474012.36261HepG2SF3A3
chr10104486694104486807+3'-UTR,CDS,intron-Proximal5.709656.41139HepG2EFTUD2
chr10104486857104486927+3'-UTR,CDS,intron-Proximal3.983074.04622HepG2GRWD1
chr10104486747104486811+3'-UTR,CDS3.138083.94979HepG2BCLAF1
chr10104492644104492739+3'-UTR,CDS,intron-Proximal4.454178.80047HepG2EFTUD2
chr10104488230104488296+3'-UTR,CDS,intron-Proximal3.057457.61685HepG2PPIG
chr10104474381104474450+5'-UTR,intron-Proximal3.705845.03370HepG2NCBP2
chr10104489464104489528+CDS,intron-Distal,intron-Proximal3.100163.05068HepG2U2AF2
chr10104489150104489195+CDS,intron-Distal,intron-Proximal3.114145.39110HepG2PRPF8
chr10104486492104486556+CDS,intron-Proximal3.8090810.42618HepG2PPIG
chr10104486715104486794+CDS,intron-Proximal3.0295410.00177HepG2BUD13
chr10104488285104488325+CDS,intron-Proximal4.911555.35117HepG2PRPF8
chr10104489669104489737+intron-Distal3.795856.87708HepG2EFTUD2
chr10104494802104494916+intron-Distal4.507418.06993HepG2DDX59
chr10104492498104492529+intron-Distal,intron-Proximal3.204274.90942HepG2SF3B4
chr10104496194104496248+intron-Distal4.148473.72818HepG2ILF3
chr10104494902104494950+intron-Distal4.8972617.11308HepG2PCBP2
chr10104489704104489808+intron-Distal3.205744.19099HepG2PRPF4
chr10104494950104495024+intron-Distal7.2163229.40935HepG2PCBP2
chr10104489712104489840+intron-Distal3.168195.24631HepG2GTF2F1
chr10104495024104495085+intron-Distal6.8680724.37680HepG2PCBP2
chr10104489764104489830+intron-Distal3.863885.51372HepG2EFTUD2
chr10104489657104489712+intron-Distal,intron-Proximal3.053213.15890HepG2GTF2F1
chr10104495103104495152+intron-Distal6.5931219.77775HepG2PCBP2
chr10104494093104494181+intron-Distal4.587284.05848HepG2QKI
chr10104495247104495308+intron-Distal6.2012116.02947HepG2PCBP2
chr10104494805104494922+intron-Distal4.881656.93250HepG2HNRNPK
chr10104490164104490243+intron-Distal4.227454.21977HepG2HNRNPL
chr10104494984104495033+intron-Distal3.124703.25356HepG2DDX59
chr10104496191104496253+intron-Distal3.365224.76325HepG2HNRNPC
chr10104495152104495216+intron-Distal5.6951924.31537HepG2PCBP2
chr10104488286104488370+intron-Proximal4.895794.86944K562AQR
chr10104486914104486958+intron-Proximal4.823594.65563K562AQR
chr10104493382104493439+intron-Proximal4.7103115.12562HepG2PRPF8
chr10104493383104493439+intron-Proximal5.317495.11689HepG2RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SFXN2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SFXN2 is not available on ENCORE database.

  • 121 RBPs can affect the levels of SFXN2.  








The Knockdown/knockout RNA-Seq assay for SFXN2 is not available on ENCORE database.





121 RBPs can affect the gene expression of SFXN2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SFXN2ENSG00000156398.8573.60910277.501701.047509.675708.08120HepG2ABCF1
SFXN2ENSG00000156398.8119.24880252.03730-1.079709.242508.26410HepG2ACO1
SFXN2ENSG00000156398.8115.7475052.655701.136203.116101.34050HepG2APOBEC3C
SFXN2ENSG00000156398.8133.20770464.22750-1.8012030.6504028.79980HepG2AUH
SFXN2ENSG00000156398.8123.66150191.62670-0.631902.548501.97070HepG2BOP1
SFXN2ENSG00000156398.8147.97490237.96200-0.685403.460602.61120HepG2CALR
SFXN2ENSG00000156398.8126.81400251.98350-0.990608.199807.17260HepG2CKAP4
SFXN2ENSG00000156398.8225.33150393.35830-0.803807.186506.24240HepG2CELF1
SFXN2ENSG00000156398.8365.53340270.409900.434802.262601.44670HepG2DDX24
SFXN2ENSG00000156398.877.97910190.84890-1.291306.988306.03570HepG2DDX3X
SFXN2ENSG00000156398.8167.12510261.32760-0.644902.377001.65400HepG2DDX55
SFXN2ENSG00000156398.892.78940199.77110-1.106304.603203.35380HepG2DDX59
SFXN2ENSG00000156398.885.64700163.89960-0.936303.587802.89180HepG2DDX6
SFXN2ENSG00000156398.8485.73440241.131701.0102012.6442011.41210HepG2DKC1
SFXN2ENSG00000156398.8339.82510209.322500.699003.744302.68320HepG2EEF2
SFXN2ENSG00000156398.8422.76150174.191701.2791011.7603010.47080HepG2EIF4A3
SFXN2ENSG00000156398.8252.08210169.560200.572002.020501.42730HepG2EIF4B
SFXN2ENSG00000156398.8400.54450240.454000.736105.337103.86880HepG2ESF1
SFXN2ENSG00000156398.8317.07250532.99850-0.749308.271907.32830HepG2ETF1
SFXN2ENSG00000156398.8109.68130280.23180-1.353308.118606.87650HepG2FIP1L1
SFXN2ENSG00000156398.8174.81010103.729200.752903.166202.32850HepG2FUBP3
SFXN2ENSG00000156398.8326.04850175.688900.892005.762804.78770HepG2FXR1
SFXN2ENSG00000156398.8456.19180173.013001.3987015.0469013.00450HepG2G3BP2
SFXN2ENSG00000156398.8231.66380151.278900.614702.811001.90540HepG2GEMIN5
SFXN2ENSG00000156398.8146.27260236.89520-0.695603.640402.46630HepG2GNB2L1
SFXN2ENSG00000156398.8173.27580321.83520-0.893306.557705.51730HepG2HNRNPF
SFXN2ENSG00000156398.8390.65720166.652201.229006.499104.89310HepG2KHSRP
SFXN2ENSG00000156398.8229.59760107.154701.099305.559703.77850HepG2KRR1
SFXN2ENSG00000156398.8532.12230175.749901.5981019.8896018.21260HepG2MAGOH
SFXN2ENSG00000156398.8382.43140176.743901.113408.318007.27480HepG2MATR3
SFXN2ENSG00000156398.8233.42880101.611001.199803.791302.12370HepG2NKRF
SFXN2ENSG00000156398.815.8052051.52670-1.704903.750902.70410HepG2PABPC1
SFXN2ENSG00000156398.8225.41310162.252400.474202.218401.66370HepG2PCBP1
SFXN2ENSG00000156398.8157.99590301.19680-0.930805.220003.82310HepG2PCBP2
SFXN2ENSG00000156398.8354.33810222.646800.670303.192801.38810HepG2PHF6
SFXN2ENSG00000156398.854.86600201.65270-1.8779012.2642010.73660HepG2PRPF8
SFXN2ENSG00000156398.8337.04700165.105801.0295010.013909.10000HepG2PTBP1
SFXN2ENSG00000156398.8326.43080424.65100-0.379501.945101.37660HepG2PUM2
SFXN2ENSG00000156398.8390.32020256.716500.604405.096604.30680HepG2PUS1
SFXN2ENSG00000156398.8264.22730178.796700.563402.855002.22250HepG2QKI
SFXN2ENSG00000156398.8100.17630290.57920-1.536408.765507.55660HepG2RAVER1
SFXN2ENSG00000156398.8119.24050445.48740-1.9015029.9064028.56750HepG2RBM22
SFXN2ENSG00000156398.8430.20640279.928100.619903.485402.36580HepG2RBM27
SFXN2ENSG00000156398.8497.01940183.740301.4355021.0957019.87510HepG2NELFE
SFXN2ENSG00000156398.8571.66130171.141101.7399033.5759031.88020HepG2RECQL
SFXN2ENSG00000156398.8103.54180346.79320-1.7439011.042609.83410HepG2RPLP0
SFXN2ENSG00000156398.8178.04730285.58840-0.681702.931901.96190HepG2RPS10
SFXN2ENSG00000156398.8157.6055056.575401.478007.277805.99190HepG2RPS3A
SFXN2ENSG00000156398.8390.76400263.534200.568202.872201.77560HepG2RPS5
SFXN2ENSG00000156398.855.33250199.48220-1.8501011.175709.76190HepG2RRP9
SFXN2ENSG00000156398.8210.18240340.11870-0.694403.613002.83890HepG2SF3A3
SFXN2ENSG00000156398.8113.80720188.35240-0.726803.020402.28480HepG2SF3B1
SFXN2ENSG00000156398.8248.44810171.882200.531402.642302.06220HepG2SF3B4
SFXN2ENSG00000156398.8115.10780209.57740-0.864503.218302.37370HepG2SNRNP70
SFXN2ENSG00000156398.8106.64080503.16040-2.2383044.9782043.59700HepG2SRFBP1
SFXN2ENSG00000156398.8536.61370179.413601.5805026.6559025.51700HepG2SRSF1
SFXN2ENSG00000156398.8204.49560395.27960-0.950809.653008.57840HepG2SRSF5
SFXN2ENSG00000156398.8899.15240436.860301.0413023.1328021.96840HepG2SSB
SFXN2ENSG00000156398.8167.98040271.57570-0.693102.646801.47350HepG2SUB1
SFXN2ENSG00000156398.8134.19430260.16490-0.955104.559803.72360HepG2SUPV3L1
SFXN2ENSG00000156398.8324.90980161.280101.010408.958408.04330HepG2TAF15
SFXN2ENSG00000156398.8197.41990105.000900.910802.869401.78470HepG2TBRG4
SFXN2ENSG00000156398.894.65190174.38990-0.881603.484702.37920HepG2TFIP11
SFXN2ENSG00000156398.878.90340239.77450-1.6035010.919809.64980HepG2U2AF1
SFXN2ENSG00000156398.840.34080167.69910-2.055606.249004.69750HepG2U2AF2
SFXN2ENSG00000156398.8234.53280414.02460-0.819904.380303.31160HepG2UBE2L3
SFXN2ENSG00000156398.8461.29530256.103300.848906.468705.37570HepG2XRN2
SFXN2ENSG00000156398.8202.73440266.99190-0.397201.967201.38570HepG2ZC3H8
SFXN2ENSG00000156398.8168.73330331.73960-0.975306.456705.71230HepG2ZNF622
SFXN2ENSG00000156398.880.34560178.23860-1.149506.688505.86210K562AGGF1
SFXN2ENSG00000156398.8122.88290195.82890-0.672303.268402.17760K562AKAP8
SFXN2ENSG00000156398.851.21900185.45840-1.8563013.3695011.77210K562AKAP8L
SFXN2ENSG00000156398.8614.83860398.462900.625703.441302.04830K562APOBEC3C
SFXN2ENSG00000156398.879.83650399.27140-2.3222013.1201011.97760K562AQR
SFXN2ENSG00000156398.8130.27010194.57730-0.578802.279601.45800K562ATP5C1
SFXN2ENSG00000156398.878.30050164.14050-1.067804.773103.61490K562BOP1
SFXN2ENSG00000156398.8198.79210305.03980-0.617703.122301.59370K562BUD13
SFXN2ENSG00000156398.8191.15500369.45750-0.950706.947104.57550K562CKAP4
SFXN2ENSG00000156398.876.57540174.53670-1.188606.921505.67390K562CPSF6
SFXN2ENSG00000156398.8113.30570209.12210-0.884105.118703.09240K562DDX19B
SFXN2ENSG00000156398.8202.51340307.46910-0.602403.794202.37090K562DDX21
SFXN2ENSG00000156398.8431.92870346.414900.318201.865701.31090K562DDX47
SFXN2ENSG00000156398.8135.17330199.61030-0.562402.770501.89590K562DKC1
SFXN2ENSG00000156398.871.31260270.21400-1.9219016.3313013.90020K562EFTUD2
SFXN2ENSG00000156398.8279.33640395.13850-0.500403.515102.71940K562EIF2S2
SFXN2ENSG00000156398.8112.85210289.38750-1.358609.865707.74510K562EIF3D
SFXN2ENSG00000156398.8265.08470166.033600.674904.154903.18860K562EIF3G
SFXN2ENSG00000156398.8183.53870314.79030-0.778305.168403.98570K562FIP1L1
SFXN2ENSG00000156398.895.32440177.57100-0.897504.088303.04490K562FMR1
SFXN2ENSG00000156398.873.60250150.50050-1.031904.453103.26830K562FTO
SFXN2ENSG00000156398.8281.9149097.685401.5289015.3709014.05370K562FXR1
SFXN2ENSG00000156398.8173.48250263.47330-0.602903.238302.00070K562GLRX3
SFXN2ENSG00000156398.8105.88280166.64620-0.654302.421101.67640K562GPKOW
SFXN2ENSG00000156398.897.64080193.60210-0.987503.906501.57370K562HLTF
SFXN2ENSG00000156398.844.78710132.91070-1.569305.320103.44010K562HNRNPA2B1
SFXN2ENSG00000156398.888.42360218.46580-1.304908.396807.40740K562HNRNPC
SFXN2ENSG00000156398.8124.32940195.03880-0.649602.583801.48500K562HNRNPF
SFXN2ENSG00000156398.895.65790222.53840-1.218109.143306.11900K562HNRNPH1
SFXN2ENSG00000156398.8469.44490313.026400.584604.436803.06410K562HNRNPL
SFXN2ENSG00000156398.8170.52790319.50960-0.905905.102703.87640K562HNRNPU
SFXN2ENSG00000156398.886.45570143.00410-0.726002.379901.44790K562IGF2BP2
SFXN2ENSG00000156398.8246.22900144.485900.769003.965801.64900K562KHSRP
SFXN2ENSG00000156398.884.41350196.84220-1.221507.232105.74390K562KIF1C
SFXN2ENSG00000156398.841.69910142.27780-1.770607.922706.24920K562KRR1
SFXN2ENSG00000156398.8136.16100211.40290-0.634702.804201.40490K562LARP7
SFXN2ENSG00000156398.899.75780188.40650-0.917304.671803.16840K562MAK16
SFXN2ENSG00000156398.8339.20320149.909101.1780011.803109.77310K562MATR3
SFXN2ENSG00000156398.895.75900162.66250-0.764402.761601.88570K562METAP2
SFXN2ENSG00000156398.856.64300154.55910-1.448206.289904.75570K562NAA15
SFXN2ENSG00000156398.8190.34240307.81760-0.693503.792002.93370K562NSUN2
SFXN2ENSG00000156398.879.53840133.64990-0.748702.655401.69660K562PCBP2
SFXN2ENSG00000156398.8180.69470269.03010-0.574202.630801.82160K562PCBP3
SFXN2ENSG00000156398.8178.18750262.94760-0.561402.258201.57680K562PRPF8
SFXN2ENSG00000156398.8131.40080195.86320-0.575902.403801.56690K562PSIP1
SFXN2ENSG00000156398.8331.77200145.957201.1845012.1443010.80390K562PTBP1
SFXN2ENSG00000156398.8789.54820492.687000.680305.106404.00020K562PUF60
SFXN2ENSG00000156398.895.99330179.21330-0.900704.643903.89560K562RBM15
SFXN2ENSG00000156398.8275.61040499.35180-0.857408.202805.52130K562RBM17
SFXN2ENSG00000156398.831.73400143.08570-2.172808.164405.17280K562RBM39
SFXN2ENSG00000156398.8270.00060147.250600.874605.758204.10160K562NELFE
SFXN2ENSG00000156398.8185.93120267.89260-0.526902.052601.35430K562RPS19
SFXN2ENSG00000156398.8324.38920183.876200.818905.680604.12880K562SAFB
SFXN2ENSG00000156398.8129.75010225.05270-0.794502.994901.35630K562SERBP1
SFXN2ENSG00000156398.8178.78560303.66880-0.764302.962902.12150K562SF3A3
SFXN2ENSG00000156398.853.14990158.46250-1.576007.979806.27160K562SF3B1
SFXN2ENSG00000156398.842.9625074.56440-0.795402.122401.37490K562SF3B4
SFXN2ENSG00000156398.842.09940122.13750-1.536604.717802.97920K562SNRNP200
SFXN2ENSG00000156398.8198.07970274.37950-0.470102.489701.38350K562SRSF7
SFXN2ENSG00000156398.8216.41940377.80900-0.803805.562903.70480K562STAU1
SFXN2ENSG00000156398.871.62710146.12050-1.028602.815801.37540K562SUPT6H
SFXN2ENSG00000156398.8143.31000254.68110-0.829604.146102.88170K562SUPV3L1
SFXN2ENSG00000156398.8464.00790206.981201.1645014.2801012.41770K562SYNCRIP
SFXN2ENSG00000156398.890.44770139.68450-0.627002.134901.42380K562TIA1
SFXN2ENSG00000156398.8120.25970188.39600-0.647602.397601.53120K562TIAL1
SFXN2ENSG00000156398.8238.98500368.34690-0.624102.765401.38460K562TRIP6
SFXN2ENSG00000156398.818.1713069.48730-1.935105.861004.14130K562U2AF1
SFXN2ENSG00000156398.816.6151071.80670-2.111606.430305.21080K562U2AF2
SFXN2ENSG00000156398.8158.35850269.50300-0.767104.021502.77130K562UCHL5
SFXN2ENSG00000156398.8106.81670186.47970-0.803902.754701.46850K562UTP18
SFXN2ENSG00000156398.8172.93230279.28070-0.691502.101201.33980K562WDR3
SFXN2ENSG00000156398.8352.78430204.744000.784903.351001.56720K562XRCC6
SFXN2ENSG00000156398.8235.00920449.88370-0.936804.570903.41990K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SFXN2 is not available on ENCORE database.





3 RBPs can affect the splicing of SFXN2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESFXN2ENSG00000156398.8chr10+1044874311044875481044867431044869141044881871044882680.308000.001260.02487includedHepG2U2AF1
SESFXN2ENSG00000156398.8chr10+1044749791044750851044743921044744381044863681044865540.071000.004540.04294includedK562AQR
SESFXN2ENSG00000156398.8chr10+1044763451044764681044743831044744381044863681044865540.197000.001700.05829includedHepG2HNRNPC
SESFXN2ENSG00000156398.8chr10+104489075104489151104488187104488286104489479104489565-0.388000.003190.09235excludedHepG2HNRNPC
SESFXN2ENSG00000156398.8chr10+1044874311044875481044867431044869141044881871044882680.251000.003400.05142includedK562HNRNPC
A3SSSFXN2ENSG00000156398.8chr10+1044914311044915401044914791044915401044894791044895650.072000.009900.05244longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SFXN2 is not avaliable on ENCORE database.