NUS1

General Information

Gene Name       : NUS1
Gene ID             : ENSG00000153989.7
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NUS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NUS1ENSG00000153989.737.6131.6434.62ENCSR000AEF
HepG2NUS1ENSG00000153989.729.6658.0943.88ENCSR985KAT
K562NUS1ENSG00000153989.732.9636.1334.55ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NUS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NUS1 RNA is bound by 28 proteins.  







eCLIP assay for NUS1 is not avaliable on ENCORE database.





28 proteins are bound to NUS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6118028304118028387+3'-UTR3.616795.22676K562IGF2BP1
chr6118030284118030370+3'-UTR3.713393.02250K562YBX3
chr6118028324118028329+3'-UTR4.273398.92807K562TARDBP
chr6118028329118028394+3'-UTR5.5512252.80799K562TARDBP
chr6118030981118031049+3'-UTR3.012823.01436K562CSTF2T
chr6118030821118030884+3'-UTR4.6823916.08546K562PUM2
chr6118030975118031051+3'-UTR3.066123.13903HepG2CSTF2
chr6117996668117996710+5'-UTR4.108284.71605K562FUS
chr6117996696117996778+5'-UTR4.1025028.50315HepG2FAM120A
chr6117996699117996774+5'-UTR3.405396.81539HepG2NCBP2
chr6117996685117996771+5'-UTR4.6905429.68554HepG2GTF2F1
chr6117996710117996780+5'-UTR3.100045.60791K562FUS
chr6117996712117996772+5'-UTR3.034107.27537K562FASTKD2
chr6117996698117996772+5'-UTR3.9572911.25636K562DROSHA
chr6117996681117996773+5'-UTR3.4683310.67728HepG2PCBP2
chr6117996684117996777+5'-UTR3.020255.84488HepG2FUS
chr6117996676117996770+5'-UTR5.0357551.09711HepG2PRPF4
chr6117996700117996773+5'-UTR3.9754516.02902K562CSTF2T
chr6117996699117996768+5'-UTR3.453888.49967HepG2RPS3
chr6117996675117996782+5'-UTR3.397746.91729HepG2FTO
chr6117996696117996782+5'-UTR4.6662321.54981K562GTF2F1
chr6117996719117996771+5'-UTR3.032097.14956K562FAM120A
chr6117996706117996771+5'-UTR5.03243400.00000HepG2DDX3X
chr6118024865118024946+CDS,intron-Proximal3.167364.20978K562AQR
chr6117996925117996975+CDS6.3902010.46216HepG2DDX3X
chr6118015251118015310+CDS3.967663.69113K562LIN28B
chr6117996935117996968+CDS3.637075.18989HepG2PRPF4
chr6117997221117997354+CDS,intron-Distal,intron-Proximal5.1904110.93557HepG2EFTUD2
chr6118015251118015315+CDS4.064603.72865HepG2LIN28B
chr6117997238117997323+CDS,intron-Proximal3.511328.16221HepG2PRPF8
chr6118028053118028119+CDS,intron-Proximal3.286894.35314HepG2U2AF2
chr6118028025118028119+CDS,intron-Proximal6.3372214.07789K562SF3B4
chr6118022094118022165+intron-Distal4.075814.13866K562PPIL4
chr6118002310118002398+intron-Distal3.752466.71645HepG2PTBP1
chr6118011075118011175+intron-Distal5.368647.60539K562LIN28B
chr6118018868118018955+intron-Distal3.136053.08145HepG2HLTF
chr6118011082118011141+intron-Distal4.253854.13513HepG2LIN28B
chr6118024898118024968+intron-Distal,intron-Proximal4.646214.96013K562PRPF8
chr6118022062118022157+intron-Distal4.671367.10262K562SAFB2
chr6118021029118021092+intron-Distal3.761503.12651K562SAFB2
chr6118002325118002401+intron-Distal3.398413.80761K562PTBP1
chr6118022082118022168+intron-Distal3.089063.10112K562UCHL5
chr6118008033118008107+intron-Distal4.146904.13641K562TARDBP
chr6118015373118015438+intron-Proximal4.527314.13847K562AQR
chr6118024869118024962+intron-Proximal3.952854.75435K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NUS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NUS1 is not available on ENCORE database.

  • 119 RBPs can affect the levels of NUS1.  








The Knockdown/knockout RNA-Seq assay for NUS1 is not available on ENCORE database.





119 RBPs can affect the gene expression of NUS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NUS1ENSG00000153989.72278.747603228.49560-0.502604.637103.44310HepG2ABCF1
NUS1ENSG00000153989.72098.612502942.62800-0.4877012.6083011.51170HepG2ACO1
NUS1ENSG00000153989.71687.510202618.46770-0.633807.061305.55900HepG2ADAR
NUS1ENSG00000153989.72139.931202956.61830-0.466405.719504.65310HepG2AKAP8L
NUS1ENSG00000153989.73255.739204041.54090-0.311902.329101.60570HepG2ASCC1
NUS1ENSG00000153989.72239.520302914.30790-0.380003.691602.08150HepG2ATP5C1
NUS1ENSG00000153989.72252.110702936.71320-0.382902.173801.34630HepG2BCCIP
NUS1ENSG00000153989.72049.111402765.92430-0.432804.751303.99330HepG2BOP1
NUS1ENSG00000153989.72148.905502942.18690-0.4533012.2406011.04240HepG2CKAP4
NUS1ENSG00000153989.72009.849502722.53610-0.437902.277201.58810HepG2CNOT7
NUS1ENSG00000153989.7813.172302370.57850-1.5436016.5782015.08670HepG2DDX21
NUS1ENSG00000153989.71420.304502187.77460-0.623304.553002.79690HepG2DDX28
NUS1ENSG00000153989.73799.243704679.09010-0.300502.170601.60930HepG2DDX3X
NUS1ENSG00000153989.71956.771402887.25750-0.561204.521803.55780HepG2DDX55
NUS1ENSG00000153989.72532.776904019.04150-0.666107.392506.42640HepG2DDX6
NUS1ENSG00000153989.71609.487302613.31190-0.6993025.8825024.08230HepG2DNAJC2
NUS1ENSG00000153989.71723.696802491.39550-0.531404.667703.49720HepG2EEF2
NUS1ENSG00000153989.71316.940502077.10360-0.657408.084806.19460HepG2EFTUD2
NUS1ENSG00000153989.72695.036303863.99280-0.519805.517404.69660HepG2EIF2S1
NUS1ENSG00000153989.71075.067802449.55990-1.1881032.2705029.13690HepG2EIF2S2
NUS1ENSG00000153989.73183.892204157.42940-0.384902.312601.68100HepG2EIF4B
NUS1ENSG00000153989.73430.354904083.05170-0.251302.027201.32250HepG2EIF4G2
NUS1ENSG00000153989.74752.785105350.90930-0.171001.914901.39510HepG2ETF1
NUS1ENSG00000153989.71946.288802875.64950-0.563208.606707.14890HepG2EWSR1
NUS1ENSG00000153989.71790.642603260.13480-0.8645011.4823010.06660HepG2FIP1L1
NUS1ENSG00000153989.73119.832004308.03770-0.465604.750103.85970HepG2FXR1
NUS1ENSG00000153989.72968.263003996.63740-0.429203.619202.86210HepG2G3BP1
NUS1ENSG00000153989.7954.659401800.84720-0.9156014.2647012.37060HepG2GEMIN5
NUS1ENSG00000153989.71836.905902878.35260-0.648007.317206.30650HepG2GPKOW
NUS1ENSG00000153989.71753.646002520.01180-0.523103.160801.96550HepG2GRSF1
NUS1ENSG00000153989.71345.249902661.98760-0.9846021.9704020.44920HepG2HNRNPA1
NUS1ENSG00000153989.71737.810802960.92480-0.7688013.8125012.37770HepG2HNRNPC
NUS1ENSG00000153989.72427.120603098.60950-0.352406.448505.41590HepG2HNRNPF
NUS1ENSG00000153989.71870.399602941.35220-0.6531019.4121017.91890HepG2HNRNPU
NUS1ENSG00000153989.72379.464203051.22870-0.358804.625903.71100HepG2IGF2BP1
NUS1ENSG00000153989.73303.177704062.60160-0.298502.171701.56540HepG2IGF2BP2
NUS1ENSG00000153989.72471.322603004.50150-0.281805.721604.70030HepG2ILF2
NUS1ENSG00000153989.71270.593304086.08290-1.6852033.8159030.40140HepG2KHSRP
NUS1ENSG00000153989.72243.557802690.05440-0.261804.539003.24410HepG2KIF1C
NUS1ENSG00000153989.73103.219604309.53910-0.473804.638303.79520HepG2MAGOH
NUS1ENSG00000153989.72935.131904333.75210-0.562205.632604.75790HepG2MATR3
NUS1ENSG00000153989.71563.924502639.10880-0.7549013.8017012.14410HepG2MSI2
NUS1ENSG00000153989.71958.518902801.61740-0.516503.498402.40070HepG2MTPAP
NUS1ENSG00000153989.72153.547704435.91180-1.0425018.4764016.93610HepG2NCBP2
NUS1ENSG00000153989.73390.533904284.63760-0.337702.972702.18270HepG2NOL12
NUS1ENSG00000153989.71636.687402650.54030-0.695503.674302.40050HepG2NONO
NUS1ENSG00000153989.71871.270202476.59160-0.404303.889801.97960HepG2NUP35
NUS1ENSG00000153989.72564.542903950.81610-0.623407.372806.20700HepG2PABPC4
NUS1ENSG00000153989.73276.368503756.58290-0.197302.460301.88050HepG2PCBP1
NUS1ENSG00000153989.71320.856301672.58200-0.340603.513802.12640HepG2PKM
NUS1ENSG00000153989.71502.988502623.45890-0.8036021.9165019.99710HepG2PPIL4
NUS1ENSG00000153989.71463.806402401.10820-0.7140019.4367017.71170HepG2PRPF4
NUS1ENSG00000153989.71390.423202228.05450-0.680306.287405.12220HepG2PRPF8
NUS1ENSG00000153989.72405.159603822.51090-0.6684020.7270019.49650HepG2PTBP1
NUS1ENSG00000153989.72789.040204089.83330-0.552308.761407.78000HepG2PUF60
NUS1ENSG00000153989.73650.282104341.27120-0.250102.996302.38520HepG2PUM1
NUS1ENSG00000153989.71762.610602997.28660-0.7659028.7929027.19420HepG2PUS1
NUS1ENSG00000153989.72901.922004139.77280-0.5125010.037008.95160HepG2QKI
NUS1ENSG00000153989.71257.698101689.69030-0.426003.151801.32880HepG2RBM14
NUS1ENSG00000153989.72805.557803426.28110-0.288403.329002.39730HepG2RBM15
NUS1ENSG00000153989.73935.835304472.40570-0.184401.944601.49030HepG2RBM22
NUS1ENSG00000153989.72732.680304254.04830-0.6385019.9809018.78330HepG2NELFE
NUS1ENSG00000153989.73461.116503962.13920-0.195002.485301.89720HepG2RECQL
NUS1ENSG00000153989.72315.649903338.21780-0.527707.485406.44330HepG2RPLP0
NUS1ENSG00000153989.7758.479701967.94810-1.3755034.2628032.51030HepG2RPS19
NUS1ENSG00000153989.72104.999803043.39260-0.531902.771701.97130HepG2RPS2
NUS1ENSG00000153989.71966.452302732.47920-0.474603.251602.38600HepG2RPS3A
NUS1ENSG00000153989.73807.433102619.430300.5395017.4620016.04130HepG2SAFB2
NUS1ENSG00000153989.71380.898101975.27280-0.516405.225603.94410HepG2SERBP1
NUS1ENSG00000153989.71084.314502458.42380-1.181004.275102.50890HepG2SF1
NUS1ENSG00000153989.72109.695402718.81680-0.365903.502002.71710HepG2SF3B1
NUS1ENSG00000153989.73439.305703979.64230-0.210502.830502.23300HepG2SF3B4
NUS1ENSG00000153989.72301.717103054.74240-0.4083011.3203010.15700HepG2SMN1
NUS1ENSG00000153989.71969.600102815.17520-0.515303.715702.59260HepG2SMNDC1
NUS1ENSG00000153989.74379.169105051.48060-0.206003.027402.51060HepG2SRFBP1
NUS1ENSG00000153989.72937.608204153.91970-0.4998014.4351013.53510HepG2SRSF1
NUS1ENSG00000153989.73249.446304037.79410-0.313403.149702.48760HepG2SRSF5
NUS1ENSG00000153989.72382.905603044.34060-0.353406.640805.63880HepG2SRSF7
NUS1ENSG00000153989.72894.356503379.46480-0.223603.208602.62350HepG2SRSF9
NUS1ENSG00000153989.73798.297204385.99110-0.207602.912002.38940HepG2SSB
NUS1ENSG00000153989.73826.713804592.35870-0.263103.266502.60200HepG2SUCLG1
NUS1ENSG00000153989.71720.988502201.88710-0.355503.366702.33620HepG2SUPT6H
NUS1ENSG00000153989.71998.115102874.44320-0.524603.916703.13330HepG2SUPV3L1
NUS1ENSG00000153989.72996.954303733.80120-0.317104.553803.86230HepG2TAF15
NUS1ENSG00000153989.71460.053102858.23940-0.9691027.2771026.00650HepG2TIAL1
NUS1ENSG00000153989.71924.268302883.61160-0.5836015.6074014.42040HepG2TRIM56
NUS1ENSG00000153989.73237.776603995.15720-0.303202.875301.98230HepG2TUFM
NUS1ENSG00000153989.72022.769004228.52390-1.0638019.9102017.69010HepG2UBE2L3
NUS1ENSG00000153989.72390.541102903.19300-0.280304.438903.59030HepG2UPF1
NUS1ENSG00000153989.73391.769702802.916700.275004.582703.84310HepG2UTP3
NUS1ENSG00000153989.71814.845402716.29290-0.581804.241502.67020HepG2XRCC5
NUS1ENSG00000153989.71697.180502829.56740-0.737407.177606.02200HepG2XRN2
NUS1ENSG00000153989.72965.541903959.62260-0.417104.435602.86100K562ABCF1
NUS1ENSG00000153989.72917.378704754.56730-0.7046011.6636010.58010K562AQR
NUS1ENSG00000153989.72004.439702501.73680-0.319705.216103.88010K562BCLAF1
NUS1ENSG00000153989.7808.125701141.72350-0.498602.608001.59260K562CCAR1
NUS1ENSG00000153989.72928.394603652.81470-0.318904.530803.09080K562CPEB4
NUS1ENSG00000153989.75189.258504211.518500.301104.711803.51950K562DKC1
NUS1ENSG00000153989.71525.445402062.24410-0.435002.201801.38750K562EFTUD2
NUS1ENSG00000153989.71732.018703126.09710-0.8519027.0678025.21690K562EIF2S2
NUS1ENSG00000153989.71484.766302010.06580-0.437005.321103.52210K562EXOSC5
NUS1ENSG00000153989.71896.319902846.38990-0.585907.936006.42570K562FIP1L1
NUS1ENSG00000153989.71630.223302316.91550-0.507104.690203.57460K562FMR1
NUS1ENSG00000153989.71501.289201963.71850-0.387403.045602.08140K562FTO
NUS1ENSG00000153989.72761.924102241.796400.300903.169801.72370K562FUS
NUS1ENSG00000153989.74620.132002950.398900.646903.215602.44430K562G3BP2
NUS1ENSG00000153989.72738.000204165.91340-0.6055010.579309.07510K562GRSF1
NUS1ENSG00000153989.71314.245502226.22970-0.7604011.4649010.32170K562HNRNPC
NUS1ENSG00000153989.71529.431001987.74740-0.378103.689202.35180K562HNRNPF
NUS1ENSG00000153989.74289.685503375.768600.345602.901801.63690K562HNRNPK
NUS1ENSG00000153989.72505.410403417.94520-0.448103.891101.60130K562KHSRP
NUS1ENSG00000153989.72755.872303544.83160-0.363204.032002.90180K562MATR3
NUS1ENSG00000153989.71418.276402122.35500-0.581505.370504.12410K562METAP2
NUS1ENSG00000153989.72297.909002805.08570-0.287703.319502.43680K562MTPAP
NUS1ENSG00000153989.72320.993603116.58770-0.425209.715308.43180K562NSUN2
NUS1ENSG00000153989.71961.649202556.79210-0.382303.090202.20950K562PCBP3
NUS1ENSG00000153989.71639.123501961.11150-0.258702.236901.51610K562POLR2G
NUS1ENSG00000153989.72788.699002006.788400.474605.008504.00280K562PRPF8
NUS1ENSG00000153989.71327.490101995.97070-0.588405.508804.17050K562PSIP1
NUS1ENSG00000153989.72350.077603450.74600-0.554208.256207.15020K562PTBP1
NUS1ENSG00000153989.74839.778306073.49780-0.327605.293303.94550K562PUM2
NUS1ENSG00000153989.74331.381403781.895200.195602.072001.54520K562RBM15
NUS1ENSG00000153989.72532.350303309.54240-0.386202.969502.09580K562RBM22
NUS1ENSG00000153989.72513.255003225.64500-0.360003.078501.58600K562RBM34
NUS1ENSG00000153989.72515.062303482.60290-0.469604.300002.90050K562NELFE
NUS1ENSG00000153989.72565.813203075.44690-0.261403.167902.29560K562SF3A3
NUS1ENSG00000153989.71317.360901726.00530-0.389803.550702.34930K562SRFBP1
NUS1ENSG00000153989.72518.972103382.73990-0.425405.071804.11850K562SRSF1
NUS1ENSG00000153989.71623.354602128.91510-0.391104.229102.88460K562SRSF4
NUS1ENSG00000153989.72505.848301967.094600.349104.086003.08380K562SYNCRIP
NUS1ENSG00000153989.72631.772803302.61810-0.327603.200402.31060K562TIA1
NUS1ENSG00000153989.71400.279901919.83520-0.455303.877902.76030K562TIAL1
NUS1ENSG00000153989.71458.748102039.16000-0.483205.422503.99240K562TRIM56
NUS1ENSG00000153989.71343.235503329.46420-1.3096031.2692027.35060K562TRIP6
NUS1ENSG00000153989.73809.800802860.841400.413203.315302.09540K562U2AF1
NUS1ENSG00000153989.74073.815902954.317000.463507.541306.21360K562U2AF2
NUS1ENSG00000153989.75082.960706570.37700-0.370304.232602.49840K562UBE2L3
NUS1ENSG00000153989.72767.064403304.59310-0.256103.825902.99310K562UPF1
NUS1ENSG00000153989.72384.002802827.62120-0.246202.122701.35760K562WDR3
NUS1ENSG00000153989.74332.521005356.27930-0.306003.001002.09710K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NUS1 is not available on ENCORE database.





3 RBPs can affect the splicing of NUS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSNUS1ENSG00000153989.7chr6+1180247301180248671180247671180248671180151541180153430.071000.000000.00000longerK562AQR
A5SSNUS1ENSG00000153989.7chr6+117996664117997248117996664117996685118014204118014330-0.127000.000020.01160shorterK562HNRNPK
A5SSNUS1ENSG00000153989.7chr6+117996664117997248117996664117996685118014204118014330-0.108000.000260.01871shorterK562SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NUS1 is not avaliable on ENCORE database.