ITPK1

General Information

Gene Name       : ITPK1
Gene ID             : ENSG00000100605.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ITPK1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ITPK1ENSG00000100605.1613.8224.8019.31ENCSR000AEF
HepG2ITPK1ENSG00000100605.1647.7332.3240.02ENCSR985KAT
K562ITPK1ENSG00000100605.1623.5221.7722.64ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ITPK1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ITPK1 RNA is bound by 10 proteins.  







eCLIP assay for ITPK1 is not avaliable on ENCORE database.





10 proteins are bound to ITPK1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr149348296793483066-3'-UTR,CDS,intron-Distal,intron-Proximal5.039724.68690HepG2PRPF8
chr149340766093407770-3'-UTR,intron-Distal4.3492110.04737K562UPF1
chr149348303093483156-3'-UTR,CDS,intron-Distal,intron-Proximal3.768754.51003HepG2PPIG
chr149340693293406974-3'-UTR,intron-Distal3.434015.15749K562YBX3
chr149340653593406621-3'-UTR,intron-Distal5.531658.40676K562UPF1
chr149358136493581433-5'-UTR,CDS,intron-Distal,intron-Proximal4.464065.34978HepG2PRPF8
chr149358150693581541-5'-UTR,CDS,intron-Distal,intron-Proximal4.605273.53084HepG2DDX3X
chr149358141193581474-5'-UTR,CDS,intron-Distal,intron-Proximal3.693446.13978HepG2PPIG
chr149341829693418357-CDS,intron-Distal3.717533.25175K562YBX3
chr149354292993542964-CDS,intron-Distal,intron-Proximal4.064364.96634HepG2PPIG
chr149352561693525655-intron-Distal4.183405.12778HepG2PCBP2
chr149352470693524824-intron-Distal6.4569718.08872HepG2PCBP2
chr149352514893525203-intron-Distal5.703908.17201HepG2PCBP2
chr149352654993526619-intron-Distal4.297604.68055HepG2CSTF2T
chr149356599293566053-intron-Distal6.8025117.30835HepG2XPO5
chr149352471893524797-intron-Distal3.812894.02963HepG2DDX59
chr149352556393525670-intron-Distal4.779335.15063HepG2CSTF2T
chr149352505293525125-intron-Distal6.2919313.20639HepG2PCBP2
chr149352467793524798-intron-Distal3.058833.57155HepG2ILF3
chr149352470793524794-intron-Distal5.203566.44863HepG2CSTF2T
chr149352585993525933-intron-Distal5.7270310.94693HepG2PCBP2
chr149352598393526028-intron-Distal4.806384.05003HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ITPK1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ITPK1 is not available on ENCORE database.

  • 118 RBPs can affect the levels of ITPK1.  








The Knockdown/knockout RNA-Seq assay for ITPK1 is not available on ENCORE database.





118 RBPs can affect the gene expression of ITPK1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ITPK1ENSG00000100605.12239.83890494.68110-1.0444010.774208.84870HepG2AATF
ITPK1ENSG00000100605.12731.39070980.61010-0.423002.424901.84870HepG2ACO1
ITPK1ENSG00000100605.12483.609401019.61840-1.076106.190505.43090HepG2AKAP1
ITPK1ENSG00000100605.12558.90040779.49180-0.479903.275002.14780HepG2AKAP8
ITPK1ENSG00000100605.12413.82600843.57170-1.027505.674504.57190HepG2ASCC1
ITPK1ENSG00000100605.12481.89280655.65250-0.444202.189801.35910HepG2BCCIP
ITPK1ENSG00000100605.12565.38110876.65230-0.632805.631604.81410HepG2BOP1
ITPK1ENSG00000100605.12808.872001280.68860-0.662905.257103.89220HepG2CCAR1
ITPK1ENSG00000100605.121093.19590801.476000.447702.291001.58320HepG2CIRBP
ITPK1ENSG00000100605.12663.69190980.15020-0.562504.074903.29710HepG2CKAP4
ITPK1ENSG00000100605.12302.82190506.61410-0.742404.648502.73800HepG2CSTF2T
ITPK1ENSG00000100605.12407.35170742.49790-0.8661012.7601011.57660HepG2CELF1
ITPK1ENSG00000100605.121269.23830798.217700.6690016.0135014.48230HepG2DAZAP1
ITPK1ENSG00000100605.12881.21750545.505600.691807.548606.48430HepG2DDX21
ITPK1ENSG00000100605.12389.95770534.04940-0.453703.064102.10190HepG2DDX24
ITPK1ENSG00000100605.12333.64030488.17170-0.549103.048501.58150HepG2DDX28
ITPK1ENSG00000100605.121568.04570976.552200.683105.237204.40000HepG2DDX3X
ITPK1ENSG00000100605.12646.67780938.11430-0.536703.654902.89590HepG2DKC1
ITPK1ENSG00000100605.12731.24990502.512200.541103.203502.45170HepG2DNAJC21
ITPK1ENSG00000100605.12445.29940590.22270-0.406502.443801.40280HepG2EFTUD2
ITPK1ENSG00000100605.12286.83740502.52500-0.809005.718104.13330HepG2AGO1
ITPK1ENSG00000100605.121080.83590806.422200.422402.781602.18680HepG2EIF2S1
ITPK1ENSG00000100605.12430.15090574.77790-0.418202.651701.76550HepG2EIF3D
ITPK1ENSG00000100605.121963.13090891.004801.1396016.9252015.35360HepG2EIF4A3
ITPK1ENSG00000100605.12606.13980867.87430-0.517802.124801.51900HepG2EIF4B
ITPK1ENSG00000100605.12566.22410787.61990-0.476103.615302.67940HepG2EIF4G1
ITPK1ENSG00000100605.12985.92860754.466300.385903.032002.18110HepG2EIF4G2
ITPK1ENSG00000100605.12750.904501106.28980-0.559005.755604.23470HepG2ESF1
ITPK1ENSG00000100605.12923.471001178.80160-0.352204.288103.56770HepG2ETF1
ITPK1ENSG00000100605.12491.05360785.96960-0.678604.534003.54210HepG2FUBP3
ITPK1ENSG00000100605.121188.23630899.551000.401402.390401.74550HepG2FXR1
ITPK1ENSG00000100605.12454.35770834.16850-0.876504.890504.01740HepG2G3BP1
ITPK1ENSG00000100605.12670.41210511.745700.389502.441401.60450HepG2GEMIN5
ITPK1ENSG00000100605.12821.66420501.111300.713303.276202.16250HepG2GNB2L1
ITPK1ENSG00000100605.12709.79860936.05220-0.399202.246901.36110HepG2HDGF
ITPK1ENSG00000100605.12317.38370525.72390-0.728102.980001.54290HepG2HLTF
ITPK1ENSG00000100605.12958.54200564.313800.764204.457803.59280HepG2HNRNPC
ITPK1ENSG00000100605.12513.46750845.36450-0.719303.383202.61310HepG2HNRNPK
ITPK1ENSG00000100605.12531.60260847.97940-0.673704.697803.06370HepG2KRR1
ITPK1ENSG00000100605.12386.39960601.50980-0.638503.386702.22610HepG2METAP2
ITPK1ENSG00000100605.121226.06100926.050900.404802.383001.79280HepG2NCBP2
ITPK1ENSG00000100605.12465.88290771.95930-0.728606.584505.45520HepG2NSUN2
ITPK1ENSG00000100605.12604.42960845.24380-0.483803.297601.55340HepG2NUP35
ITPK1ENSG00000100605.12526.49810306.021900.782702.407501.59030HepG2PABPC1
ITPK1ENSG00000100605.12367.02960554.87220-0.596306.078204.90050HepG2PARN
ITPK1ENSG00000100605.12654.70670907.38940-0.470905.553904.74050HepG2PCBP1
ITPK1ENSG00000100605.12679.27970499.993500.442003.840702.98530HepG2PPIL4
ITPK1ENSG00000100605.12618.59530766.58590-0.309502.529301.78600HepG2PRPF4
ITPK1ENSG00000100605.12643.83740923.35600-0.520205.942605.20220HepG2PTBP1
ITPK1ENSG00000100605.121178.28110755.615800.640908.321507.36190HepG2PUF60
ITPK1ENSG00000100605.12616.46440998.77890-0.696105.472404.65940HepG2PUS1
ITPK1ENSG00000100605.12549.67070999.90360-0.8632013.8367012.59420HepG2QKI
ITPK1ENSG00000100605.12918.878401363.49530-0.569407.757006.42410HepG2RBM15
ITPK1ENSG00000100605.12439.31930907.51980-1.0467010.518109.26290HepG2RBM25
ITPK1ENSG00000100605.12869.303701027.56230-0.241301.793001.33730HepG2NELFE
ITPK1ENSG00000100605.12596.57610957.11500-0.6820010.439509.35770HepG2RECQL
ITPK1ENSG00000100605.12667.18320499.219500.418304.173503.41030HepG2SAFB2
ITPK1ENSG00000100605.12633.67400861.61140-0.443302.604801.91920HepG2SF3B1
ITPK1ENSG00000100605.12603.48730961.23710-0.6716010.012708.99190HepG2SF3B4
ITPK1ENSG00000100605.12816.37840582.167600.487706.585005.65800HepG2SMN1
ITPK1ENSG00000100605.12268.16800958.71120-1.8380023.4169021.22540HepG2SNRNP70
ITPK1ENSG00000100605.12762.850101112.77360-0.544708.889308.13150HepG2SRFBP1
ITPK1ENSG00000100605.12400.88830613.93790-0.614903.344601.55520HepG2SRP68
ITPK1ENSG00000100605.12774.490001003.36250-0.373503.791603.26010HepG2SRSF1
ITPK1ENSG00000100605.12526.03150927.23550-0.817804.242702.97520HepG2SRSF3
ITPK1ENSG00000100605.12612.22740746.11870-0.285301.967701.42830HepG2SRSF5
ITPK1ENSG00000100605.12696.21110824.13890-0.243401.902301.31390HepG2SRSF7
ITPK1ENSG00000100605.12548.67850816.32250-0.573207.757806.91870HepG2SRSF9
ITPK1ENSG00000100605.12726.47140966.10690-0.411305.074004.42070HepG2SSB
ITPK1ENSG00000100605.12485.41000845.65540-0.800907.634205.65680HepG2SSRP1
ITPK1ENSG00000100605.12450.26230861.21130-0.935607.909205.95900HepG2STAU1
ITPK1ENSG00000100605.12429.25710641.69860-0.580103.012202.31020HepG2SUPV3L1
ITPK1ENSG00000100605.12324.09830901.96970-1.4766028.4133026.86300HepG2TAF15
ITPK1ENSG00000100605.12635.78930848.72850-0.416802.938502.19410HepG2TARDBP
ITPK1ENSG00000100605.12266.09380430.05220-0.692602.961201.93120HepG2TFIP11
ITPK1ENSG00000100605.12552.19050828.67230-0.585606.274805.02010HepG2TIA1
ITPK1ENSG00000100605.12796.31760544.685400.547805.740605.07060HepG2TIAL1
ITPK1ENSG00000100605.121131.87140918.297400.301603.127402.49720HepG2UTP3
ITPK1ENSG00000100605.12277.35770492.07800-0.827104.139602.58890HepG2XRCC5
ITPK1ENSG00000100605.12335.54780631.68470-0.912705.018604.05080HepG2XRN2
ITPK1ENSG00000100605.12581.61200756.50600-0.379303.860703.09010HepG2ZC3H8
ITPK1ENSG00000100605.121417.096501046.083200.437808.086607.27920HepG2ZNF622
ITPK1ENSG00000100605.12272.00020499.95440-0.878204.716602.98400HepG2ZRANB2
ITPK1ENSG00000100605.12693.262101076.05230-0.634306.534104.65840K562ABCF1
ITPK1ENSG00000100605.12535.681401078.02070-1.0089014.0195012.84190K562AQR
ITPK1ENSG00000100605.12318.04900548.71100-0.786806.591305.23140K562BOP1
ITPK1ENSG00000100605.12547.02790749.56390-0.454402.847201.40550K562BUD13
ITPK1ENSG00000100605.12633.14430828.69790-0.388303.021201.78040K562CCDC124
ITPK1ENSG00000100605.12893.450401161.93850-0.379104.321102.91990K562CPEB4
ITPK1ENSG00000100605.12455.80410583.43330-0.356202.302001.58010K562CPSF6
ITPK1ENSG00000100605.121205.655601666.70070-0.467206.436404.96080K562CELF1
ITPK1ENSG00000100605.12407.10420251.037300.697403.664902.75820K562EIF3G
ITPK1ENSG00000100605.121017.559201355.24910-0.413405.630904.31340K562EIF4G2
ITPK1ENSG00000100605.12362.06980634.72950-0.809904.197002.76240K562FKBP4
ITPK1ENSG00000100605.12422.93110593.63720-0.489203.214802.28780K562FMR1
ITPK1ENSG00000100605.1251.55090221.58080-2.1038016.1541014.09540K562G3BP2
ITPK1ENSG00000100605.12804.771301031.72770-0.358403.464902.18990K562GLRX3
ITPK1ENSG00000100605.12471.56610730.05410-0.630503.816903.12980K562HNRNPC
ITPK1ENSG00000100605.12262.35930382.15410-0.542602.831701.58400K562HNRNPK
ITPK1ENSG00000100605.12476.96350636.30640-0.415802.266901.42870K562HNRNPM
ITPK1ENSG00000100605.12578.12790940.51960-0.702103.764502.08260K562ILF2
ITPK1ENSG00000100605.12558.98120765.75280-0.454103.532602.58820K562KIF1C
ITPK1ENSG00000100605.12210.65070475.64420-1.175003.844602.73050K562KRR1
ITPK1ENSG00000100605.121105.048601444.50860-0.386503.575602.28990K562MSI2
ITPK1ENSG00000100605.12400.50350532.30380-0.410402.720501.50300K562NCBP2
ITPK1ENSG00000100605.121141.909901482.53630-0.376603.312201.66400K562NOL12
ITPK1ENSG00000100605.12872.461101205.23810-0.466208.274507.08240K562NSUN2
ITPK1ENSG00000100605.12556.53070393.100000.501504.026902.38600K562PCBP1
ITPK1ENSG00000100605.12662.152201016.59530-0.618504.416903.36720K562PCBP3
ITPK1ENSG00000100605.121101.312901392.57840-0.338503.231201.68380K562PNPT1
ITPK1ENSG00000100605.12528.52890779.71360-0.561004.431003.41470K562POLR2G
ITPK1ENSG00000100605.121206.157701478.63700-0.293802.342401.59210K562PUF60
ITPK1ENSG00000100605.121113.403301573.06080-0.498606.887005.14040K562PUM1
ITPK1ENSG00000100605.1294.09990211.38820-1.167604.939802.94850K562RAVER1
ITPK1ENSG00000100605.12839.66620597.623500.490504.068602.86390K562RCC2
ITPK1ENSG00000100605.12469.79670295.746200.667604.000202.76880K562RPS3
ITPK1ENSG00000100605.12783.463401189.24600-0.602109.716808.25830K562SF3A3
ITPK1ENSG00000100605.12316.86720529.76880-0.741505.214003.85690K562SF3B1
ITPK1ENSG00000100605.12996.696501218.40670-0.289803.353902.33510K562SRPK2
ITPK1ENSG00000100605.12527.00340383.021900.460303.087802.34430K562SRSF1
ITPK1ENSG00000100605.12418.40750285.470900.551503.308802.14380K562SRSF4
ITPK1ENSG00000100605.12650.384201014.91840-0.642006.540604.39890K562SSRP1
ITPK1ENSG00000100605.12639.75320928.24060-0.537004.187502.58800K562STAU1
ITPK1ENSG00000100605.12559.16190387.636600.528503.718602.89270K562TARDBP
ITPK1ENSG00000100605.12146.81740230.85350-0.653003.182101.46430K562TBRG4
ITPK1ENSG00000100605.12537.48680373.921000.523403.972002.96650K562TIA1
ITPK1ENSG00000100605.12544.33000366.943400.568804.014102.65950K562TRA2A
ITPK1ENSG00000100605.12668.38470904.72260-0.436803.131701.63850K562TRIP6
ITPK1ENSG00000100605.12136.76610214.64730-0.650302.738301.65230K562U2AF1
ITPK1ENSG00000100605.12114.33290221.72860-0.955606.223505.02760K562U2AF2
ITPK1ENSG00000100605.121071.489301277.93870-0.254202.671801.96570K562UPF1
ITPK1ENSG00000100605.12673.295001041.24540-0.629002.802901.59380K562UTP3
ITPK1ENSG00000100605.12846.956301093.49320-0.368603.196202.25970K562WDR3
ITPK1ENSG00000100605.12856.373201137.09620-0.409005.755904.58160K562WDR43
ITPK1ENSG00000100605.121028.683701277.03470-0.312002.536601.30440K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ITPK1 is not available on ENCORE database.





2 RBPs can affect the splicing of ITPK1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEITPK1ENSG00000100605.12chr14-935429399354296493483020934831469358141393581562-0.180000.000250.00995excludedHepG2SF3A3
SEITPK1ENSG00000100605.12chr14-935429399354296493483020934831469358141393581562-0.215000.001920.04606excludedK562AGGF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ITPK1 is not avaliable on ENCORE database.