DSC2

General Information

Gene Name       : DSC2
Gene ID             : ENSG00000134755.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DSC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DSC2ENSG00000134755.152.732.072.40ENCSR000AEF
HepG2DSC2ENSG00000134755.1510.2416.3613.30ENCSR985KAT
K562DSC2ENSG00000134755.156.026.386.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DSC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DSC2 RNA is bound by 13 proteins.  







eCLIP assay for DSC2 is not avaliable on ENCORE database.





13 proteins are bound to DSC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr182864702028647129-3'-UTR,intron-Distal3.988517.90541HepG2FUBP3
chr182864687728646947-3'-UTR,intron-Distal5.177546.43721K562PUM2
chr182864700028647098-3'-UTR,intron-Distal3.543494.79415HepG2KHSRP
chr182868225928682353-5'-UTR,intron-Distal4.923174.97000K562DDX3X
chr182868218728682353-5'-UTR,intron-Distal3.012454.23993HepG2NCBP2
chr182868197328682068-5'-UTR,intron-Distal,intron-Proximal4.2034713.46198HepG2DDX3X
chr182868224628682367-5'-UTR,intron-Distal4.6318237.08616HepG2DDX3X
chr182868208628682168-5'-UTR,intron-Distal6.1329119.15345HepG2DDX3X
chr182865481128654874-CDS,intron-Distal,intron-Proximal3.636474.62153HepG2LIN28B
chr182865077028650817-CDS,intron-Distal,intron-Proximal4.378973.60906K562SND1
chr182866660528666640-CDS,intron-Distal3.657383.02850K562YBX3
chr182867349128673568-CDS,intron-Distal,intron-Proximal4.827995.68502HepG2PRPF8
chr182866291028663008-CDS,intron-Distal3.943826.88279HepG2LIN28B
chr182866290328662995-CDS,intron-Distal4.166974.34615K562LIN28B
chr182866943528669528-CDS,intron-Distal3.517393.20659K562SND1
chr182865469328654769-CDS,intron-Distal3.369663.20659K562SND1
chr182867217728672223-CDS,intron-Distal3.828133.02250K562YBX3
chr182866220328662363-CDS,intron-Distal,intron-Proximal3.336173.81692HepG2LIN28B
chr182866006528660100-CDS,intron-Distal4.187843.71570HepG2BCLAF1
chr182868148328681569-intron-Distal4.078543.25631HepG2PRPF4
chr182867490828674991-intron-Distal3.990773.84389HepG2SUGP2
chr182868163928681729-intron-Distal3.133973.87304HepG2FAM120A
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DSC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DSC2 is not available on ENCORE database.

  • 121 RBPs can affect the levels of DSC2.  








The Knockdown/knockout RNA-Seq assay for DSC2 is not available on ENCORE database.





121 RBPs can affect the gene expression of DSC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DSC2ENSG00000134755.102290.711201062.679901.1080048.5377046.76840HepG2ACO1
DSC2ENSG00000134755.102929.495002323.871700.334002.154901.67900HepG2AKAP1
DSC2ENSG00000134755.102012.909401067.587400.9148011.161309.75510HepG2AKAP8L
DSC2ENSG00000134755.10831.271301435.75610-0.7884018.3918016.91370HepG2AUH
DSC2ENSG00000134755.10467.840701036.64520-1.1478010.522908.63790HepG2BCCIP
DSC2ENSG00000134755.101079.49560855.908800.334702.816401.57300HepG2BUD13
DSC2ENSG00000134755.101589.321801060.467700.583604.104503.18980HepG2CALR
DSC2ENSG00000134755.102528.665801826.812800.468904.540503.56290HepG2CIRBP
DSC2ENSG00000134755.10874.407201062.34640-0.280903.054502.36300HepG2CKAP4
DSC2ENSG00000134755.10723.767701288.44200-0.832004.192503.24570HepG2CNOT7
DSC2ENSG00000134755.102318.296101183.391700.9700018.1353016.55770HepG2CPSF6
DSC2ENSG00000134755.101436.84050940.828700.610808.306106.49390HepG2CPSF7
DSC2ENSG00000134755.101005.59420640.488200.650707.669306.01990HepG2CSTF2
DSC2ENSG00000134755.101152.456701348.97210-0.227101.933801.37800HepG2CELF1
DSC2ENSG00000134755.10929.354701450.43050-0.6422015.0147013.52790HepG2DAZAP1
DSC2ENSG00000134755.10811.601601041.44370-0.359702.747302.07080HepG2DDX21
DSC2ENSG00000134755.101320.663101018.991600.374003.447602.42200HepG2DDX24
DSC2ENSG00000134755.10525.24930772.29810-0.556203.447701.88630HepG2DDX28
DSC2ENSG00000134755.101022.345301435.59440-0.489804.564802.92520HepG2DDX47
DSC2ENSG00000134755.102130.767101019.179401.0639016.4152014.74990HepG2DDX55
DSC2ENSG00000134755.102472.307901343.820200.879406.412504.95340HepG2DDX59
DSC2ENSG00000134755.101421.724901016.670200.483707.612506.59420HepG2DKC1
DSC2ENSG00000134755.10698.32940926.07700-0.407203.488102.70530HepG2DNAJC21
DSC2ENSG00000134755.10539.96000917.83920-0.7654015.7545014.32270HepG2DNAJC2
DSC2ENSG00000134755.101252.51280917.471700.449003.633102.58670HepG2EEF2
DSC2ENSG00000134755.101457.20550958.897900.603704.767203.30840HepG2AGO1
DSC2ENSG00000134755.101108.77940866.587500.355503.326102.03540HepG2EIF2S2
DSC2ENSG00000134755.101479.50800744.824300.9900014.3568012.48500HepG2EIF3D
DSC2ENSG00000134755.101520.414101977.98550-0.379602.083901.48270HepG2EIF4B
DSC2ENSG00000134755.10826.541101430.97810-0.7918017.8320016.09690HepG2EIF4G1
DSC2ENSG00000134755.101390.29170989.517600.490505.051103.61910HepG2ESF1
DSC2ENSG00000134755.102857.060701648.388300.7934026.3422024.81070HepG2ETF1
DSC2ENSG00000134755.102020.965501153.277600.8092010.025108.68120HepG2FIP1L1
DSC2ENSG00000134755.101188.32200848.385500.486004.345202.78020HepG2FKBP4
DSC2ENSG00000134755.101140.551702049.68570-0.8457011.9789010.64110HepG2FXR1
DSC2ENSG00000134755.101117.202102018.54470-0.8534012.4754010.58610HepG2G3BP2
DSC2ENSG00000134755.101035.73750663.182300.643106.317204.96690HepG2GEMIN5
DSC2ENSG00000134755.101406.68570991.958700.503804.706503.37620HepG2GNB2L1
DSC2ENSG00000134755.102125.040901341.533900.663507.218606.21570HepG2GPKOW
DSC2ENSG00000134755.102010.563601242.830000.693904.354902.58320HepG2HLTF
DSC2ENSG00000134755.101800.815201333.009200.433902.972402.00920HepG2HNRNPA2B1
DSC2ENSG00000134755.10840.949001018.38340-0.276202.023001.40320HepG2HNRNPF
DSC2ENSG00000134755.101561.207901925.22510-0.302402.228301.59640HepG2HNRNPK
DSC2ENSG00000134755.102370.240701280.244400.8885014.4500013.16640HepG2HNRNPLL
DSC2ENSG00000134755.10724.745701033.06330-0.511407.398606.44470HepG2HNRNPU
DSC2ENSG00000134755.101877.355301377.591600.446502.562201.38400HepG2HSPD1
DSC2ENSG00000134755.10898.366601055.24330-0.232202.235101.56800HepG2ILF2
DSC2ENSG00000134755.10778.144101020.43840-0.391102.779701.56330HepG2LIN28B
DSC2ENSG00000134755.101526.253902061.89960-0.434003.241402.56280HepG2MATR3
DSC2ENSG00000134755.101483.57100933.668500.668009.787308.35640HepG2MSI2
DSC2ENSG00000134755.101000.18870783.937800.351402.663301.47130HepG2NAA15
DSC2ENSG00000134755.101664.125002110.48760-0.342802.315701.73400HepG2NCBP2
DSC2ENSG00000134755.101197.08800878.671900.446004.030802.30640HepG2NIP7
DSC2ENSG00000134755.101903.497901135.132800.7457010.671309.27910HepG2NSUN2
DSC2ENSG00000134755.10891.348201823.71320-1.0328034.2531032.52590HepG2PCBP1
DSC2ENSG00000134755.101103.57070891.291200.308103.103802.29010HepG2PRPF4
DSC2ENSG00000134755.101143.69840786.529800.540005.154004.08620HepG2PRPF8
DSC2ENSG00000134755.10849.403801855.69910-1.1274037.7863036.24170HepG2PTBP1
DSC2ENSG00000134755.102067.432901372.944600.590507.341406.42980HepG2PUF60
DSC2ENSG00000134755.101829.390701457.456100.327805.676504.89020HepG2PUM1
DSC2ENSG00000134755.102222.859101456.382300.6099010.748809.47540HepG2PUM2
DSC2ENSG00000134755.10740.178801082.39340-0.548309.070908.06230HepG2PUS1
DSC2ENSG00000134755.101056.756602009.76220-0.9274023.0647021.51860HepG2QKI
DSC2ENSG00000134755.103040.322001184.981601.3593014.7763013.26840HepG2RAVER1
DSC2ENSG00000134755.103290.843901377.758401.2560054.1014052.38080HepG2RBM22
DSC2ENSG00000134755.102331.527901823.990600.354103.687302.91630HepG2RBM25
DSC2ENSG00000134755.101315.74230951.513300.467503.708402.47900HepG2RCC2
DSC2ENSG00000134755.101669.084902065.21270-0.307204.112603.47630HepG2NELFE
DSC2ENSG00000134755.101289.358301923.46900-0.5771012.2652011.10720HepG2RECQL
DSC2ENSG00000134755.101587.435901096.919000.533106.055005.10130HepG2RPLP0
DSC2ENSG00000134755.10951.42020724.709000.392603.266602.60570HepG2RPS19
DSC2ENSG00000134755.10860.144301292.83920-0.587903.062702.22210HepG2RPS3A
DSC2ENSG00000134755.101553.213401103.124200.493604.784903.35910HepG2RPS5
DSC2ENSG00000134755.10751.116701289.01870-0.779205.883303.70450HepG2RTF1
DSC2ENSG00000134755.102739.119901416.162200.9516010.356108.98690HepG2SF3A3
DSC2ENSG00000134755.101451.136001932.01750-0.412906.744405.88510HepG2SF3B4
DSC2ENSG00000134755.101813.976901316.470200.462409.880008.68130HepG2SLBP
DSC2ENSG00000134755.101444.377901072.895700.428807.759006.76710HepG2SMN1
DSC2ENSG00000134755.10544.960601207.84480-1.1482013.2670011.11690HepG2SMNDC1
DSC2ENSG00000134755.102244.810501409.999200.670804.968503.91000HepG2SNRNP70
DSC2ENSG00000134755.103945.810101556.146501.3422087.4653085.66810HepG2SRFBP1
DSC2ENSG00000134755.102115.538001363.431300.633705.642004.17040HepG2SRSF3
DSC2ENSG00000134755.102182.298901355.600500.6868017.7225016.33280HepG2SRSF5
DSC2ENSG00000134755.102059.965601640.621300.328305.067604.36140HepG2SRSF9
DSC2ENSG00000134755.101979.568401107.374000.837907.245305.35160HepG2SUB1
DSC2ENSG00000134755.101966.077201541.676100.350706.017305.16370HepG2SUCLG1
DSC2ENSG00000134755.101058.14800778.989400.441804.592303.39650HepG2SUPT6H
DSC2ENSG00000134755.102458.197901014.668801.2765024.0118022.37610HepG2SUPV3L1
DSC2ENSG00000134755.10838.420001812.61310-1.1123033.1934031.53300HepG2TAF15
DSC2ENSG00000134755.101574.823601247.663900.335902.649101.93730HepG2TARDBP
DSC2ENSG00000134755.101028.32990680.152700.596305.893404.52380HepG2TFIP11
DSC2ENSG00000134755.101301.565301665.53870-0.355703.497902.56190HepG2TIA1
DSC2ENSG00000134755.10635.713101012.78250-0.6719012.0055010.95100HepG2TRIM56
DSC2ENSG00000134755.101891.274501341.332900.495606.454105.03430HepG2TUFM
DSC2ENSG00000134755.101317.61820986.714100.417103.527602.82320HepG2U2AF1
DSC2ENSG00000134755.102308.736901250.074300.885002.626101.66540HepG2U2AF2
DSC2ENSG00000134755.10283.80280599.45860-1.0788010.059908.61460HepG2UCHL5
DSC2ENSG00000134755.101547.444401255.915900.301003.849203.04550HepG2UPF1
DSC2ENSG00000134755.103309.742701381.272001.2606086.2681084.35660HepG2ZNF622
DSC2ENSG00000134755.101150.68300833.707200.464803.864402.39420K562ABCF1
DSC2ENSG00000134755.10746.35040540.722000.464903.164202.23030K562BOP1
DSC2ENSG00000134755.10797.66070580.693900.457902.962901.48770K562BUD13
DSC2ENSG00000134755.101107.38220727.324600.606403.316802.13450K562CNOT7
DSC2ENSG00000134755.10870.81590574.913400.598906.343305.15620K562CPSF6
DSC2ENSG00000134755.101563.228801213.024700.365804.011502.82760K562CELF1
DSC2ENSG00000134755.10992.29700827.592300.261802.231201.63590K562DDX47
DSC2ENSG00000134755.10515.85440678.08420-0.394503.567002.55550K562DKC1
DSC2ENSG00000134755.10362.99640226.631600.679504.411602.68410K562DNAJC21
DSC2ENSG00000134755.10354.09640487.33640-0.460802.706501.80470K562EFTUD2
DSC2ENSG00000134755.10837.22260630.296400.409504.058703.21260K562EIF2S2
DSC2ENSG00000134755.101390.53060986.673700.494907.423805.90090K562EIF4G2
DSC2ENSG00000134755.10901.48360637.156200.500603.084301.36130K562ESF1
DSC2ENSG00000134755.10577.63700357.826000.690805.423303.74650K562FKBP4
DSC2ENSG00000134755.10898.87110585.017400.619505.821504.57080K562FMR1
DSC2ENSG00000134755.10818.79270495.879700.723405.144003.85390K562FTO
DSC2ENSG00000134755.10739.40760470.656100.651603.828202.96640K562G3BP2
DSC2ENSG00000134755.10880.71070623.830600.497405.526903.93850K562GLRX3
DSC2ENSG00000134755.10793.49120548.877300.531604.527503.51480K562GPKOW
DSC2ENSG00000134755.10587.92980412.524000.511103.886203.19350K562HNRNPC
DSC2ENSG00000134755.10309.78150492.88830-0.670004.452603.25200K562HNRNPM
DSC2ENSG00000134755.10456.09080609.51000-0.418302.911301.68340K562IGF2BP3
DSC2ENSG00000134755.101280.62830664.171400.947106.682604.42870K562ILF2
DSC2ENSG00000134755.10379.23900220.180400.784305.497103.39750K562ILF3
DSC2ENSG00000134755.10392.96640212.799600.884807.010804.69200K562KHDRBS1
DSC2ENSG00000134755.101622.746301051.722800.625608.025806.15040K562MSI2
DSC2ENSG00000134755.10956.70990728.744600.392602.979802.20880K562NSUN2
DSC2ENSG00000134755.101219.03000698.748300.802805.380503.64150K562PABPC1
DSC2ENSG00000134755.10844.45630641.624200.396202.320801.55950K562PCBP3
DSC2ENSG00000134755.10444.41690633.84760-0.512203.451401.68460K562PKM
DSC2ENSG00000134755.10627.08640492.124000.349502.319801.58630K562POLR2G
DSC2ENSG00000134755.101384.480701076.557100.362803.272002.38590K562PUF60
DSC2ENSG00000134755.101560.621301144.934600.446805.804304.20930K562PUM1
DSC2ENSG00000134755.101646.519301121.965200.553309.651607.83340K562PUM2
DSC2ENSG00000134755.10457.11220624.94930-0.451202.962002.40370K562PUS1
DSC2ENSG00000134755.10237.48670337.31420-0.506202.770101.77980K562RCC2
DSC2ENSG00000134755.10243.02790457.19690-0.911703.095201.79870K562SF1
DSC2ENSG00000134755.10885.61260719.072200.300402.156101.42830K562SF3A3
DSC2ENSG00000134755.10696.68350522.087200.416102.273701.40210K562SF3B1
DSC2ENSG00000134755.10364.64000232.133800.651404.199702.61980K562SLBP
DSC2ENSG00000134755.10655.87840522.395000.328202.609001.37210K562SSB
DSC2ENSG00000134755.10680.27860459.125600.567103.918402.69380K562SUPV3L1
DSC2ENSG00000134755.10331.70080493.64590-0.573604.555703.49410K562SYNCRIP
DSC2ENSG00000134755.10461.84190585.71350-0.342802.137301.42560K562TIA1
DSC2ENSG00000134755.10596.34740471.076200.340102.244901.52230K562U2AF2
DSC2ENSG00000134755.10480.25800772.70270-0.6861010.253608.98330K562UPF1
DSC2ENSG00000134755.10831.92900661.178400.331302.116901.35240K562WDR3
DSC2ENSG00000134755.101453.81810864.062800.7505011.105209.24790K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DSC2 is not available on ENCORE database.





4 RBPs can affect the splicing of DSC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDSC2ENSG00000134755.10chr18-2864826428648310286459392864817828648859286491170.310000.000020.00086includedK562SF3B4
SEDSC2ENSG00000134755.10chr18-286628912866302628662203286623892866653828666705-0.058000.000280.00479excludedHepG2U2AF2
SEDSC2ENSG00000134755.10chr18-2864826428648310286459392864817828648859286491170.208000.000000.00000includedHepG2AKAP1
SEDSC2ENSG00000134755.10chr18-2864826428648310286459392864817828648859286490690.165000.000010.00195includedHepG2IGF2BP3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DSC2 is not avaliable on ENCORE database.