COPB1

General Information

Gene Name : COPB1
Gene ID : ENSG00000129083.12
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: COPB1)

Not Available

Antibody Validation

View validation images for all COPB1 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	COPB1	ENSG00000129083.12	67.80	64.96	66.38	ENCSR000AEF
HepG2	COPB1	ENSG00000129083.12	70.86	93.83	82.34	ENCSR985KAT
K562	COPB1	ENSG00000129083.12	65.85	61.63	63.74	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
COPB1	ENCAB996UZN	A304-724A	1			Released, ENCODE4		BGKcLV46-11, Submitted, ENCORE2
COPB1	ENCAB732UJL	A304-723A	1			Released, ENCODE4		BGKcLV46-11, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
COPB1	K562	CRISPR	BGKcLV28-31,BGKcLV28-32	BGKcLV28-1,BGKcLV28-2	25.8,36.3	NotSatisfied	ENCODE4
COPB1	K562	CRISPR	BGKcLV35-13,BGKcLV35-14	BGKcLV35-1,BGKcLV35-2	54.1,40.8	NotSatisfied	ENCORE2
COPB1	K562	CRISPR	BGKcLV46-9,BGKcLV46-10	BGKcLV46-1,BGKcLV46-2	50.5,53.2	NotSatisfied	ENCORE2
COPB1	K562	CRISPR	COPB1-BGKcLV46-11,COPB1-BGKcLV46-12	NT-BGKcLV46-1,NT-BGKcLV46-2	80.4,76.9	Submitting	ENCORE2
COPB1	HepG2	CRISPR	BGHcLV29-31,BGHcLV29-32	BGHcLV29-1,BGHcLV29-2	0,2	NotSatisfied	ENCODE4
COPB1	HepG2	CRISPR	BGHcLV34-11,BGHcLV34-12	BGHcLV34-1,BGHcLV34-2	0.0,0.0	NotSatisfied	ENCORE2
COPB1	HepG2	CRISPR	BGHcLV47-9,BGHcLV47-10	BGHcLV47-1,BGHcLV47-2	60.0,59.2	LibPreping	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
COPB1	Product_ID: A304-723A Lot_ID: 1 Source: Bethyl Labs Target Name: COPB1-human
COPB1	Product_ID: A304-724A Lot_ID: 1 Source: Bethyl Labs Target Name: COPB1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for COPB1 is not avaliable on ENCORE database.

Proteins bound to RNA

COPB1 RNA is bound by 48 proteins.

CanvasJS.com

eCLIP assay for COPB1 is not avaliable on ENCORE database.

48 proteins are bound to COPB1 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr11	14521059	14521130	-	intron-Distal	7.87385	58.46593	K562	GTF2F1
chr11	14520486	14520563	-	3'-UTR,5'-UTR,intron-Distal,intron-Proximal	6.18872	48.61699	K562	SF3B4
chr11	14521065	14521138	-	intron-Distal	5.70660	40.80239	HepG2	PRPF4
chr11	14521293	14521389	-	5'-UTR,intron-Distal,intron-Proximal	4.50468	32.60350	K562	DDX3X
chr11	14479111	14479195	-	3'-UTR,intron-Distal	5.65903	32.39336	HepG2	SUB1
chr11	14521058	14521132	-	intron-Distal	4.11888	32.05223	HepG2	FAM120A
chr11	14521012	14521124	-	intron-Distal	3.67103	31.47792	K562	DROSHA
chr11	14520909	14520951	-	intron-Distal	4.93925	30.48265	K562	CSTF2T
chr11	14521058	14521130	-	intron-Distal	4.50060	29.28265	K562	CSTF2T
chr11	14497364	14497466	-	CDS,intron-Distal,intron-Proximal	4.20927	28.53220	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 167 entries

eCLIP assay for COPB1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for COPB1 is not available on ENCORE database.
99 RBPs can affect the levels of COPB1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for COPB1 is not available on ENCORE database.

99 RBPs can affect the gene expression of COPB1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
COPB1	ENSG00000129083.8	1703.85390	3602.54860	-1.08020	53.13640	50.76520	HepG2	HNRNPU
COPB1	ENSG00000129083.8	2446.33100	3741.41200	-0.61300	25.96030	24.31740	HepG2	SMN1
COPB1	ENSG00000129083.8	4543.27420	8522.69680	-0.90760	20.94510	19.19100	K562	PTBP1
COPB1	ENSG00000129083.8	2088.21460	3500.71650	-0.74540	17.99360	16.92280	HepG2	TIAL1
COPB1	ENSG00000129083.8	3722.53980	7456.96600	-1.00230	17.64550	16.22820	K562	FXR1
COPB1	ENSG00000129083.8	2804.66880	4049.78720	-0.53000	16.60610	15.32260	HepG2	PUS1
COPB1	ENSG00000129083.8	2406.33310	3531.83060	-0.55360	15.25770	14.08300	HepG2	TRIM56
COPB1	ENSG00000129083.8	5344.95570	8772.33830	-0.71480	14.70410	12.65320	K562	MAGOH
COPB1	ENSG00000129083.8	2347.62080	3357.45360	-0.51620	13.74230	12.55940	HepG2	UTP3
COPB1	ENSG00000129083.8	3859.76100	5529.02860	-0.51850	12.53220	11.59110	HepG2	RBM22
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 115 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for COPB1 is not available on ENCORE database.

2 RBPs can affect the splicing of COPB1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	COPB1	ENSG00000129083.8	chr11	-	14498464	14498604			14498464	14498561	14501114	14501363	0.09300	0.00000	0.00000	longer	K562	AQR
A3SS	COPB1	ENSG00000129083.8	chr11	-	14481753	14481979			14481753	14481843	14482731	14482920	0.06100	0.00000	0.00000	longer	K562	AQR
A3SS	COPB1	ENSG00000129083.8	chr11	-	14482731	14482965			14482731	14482877	14486456	14486576	0.08700	0.00000	0.00000	longer	K562	AQR
A3SS	COPB1	ENSG00000129083.8	chr11	-	14520383	14520603			14520383	14520531	14521252	14521441	0.07000	0.00002	0.00018	longer	K562	AQR
MXE	COPB1	ENSG00000129083.8	chr11	-	14481753	14481843	14482731	14482877	14480077	14480233	14486456	14486576	0.12800	0.00004	0.00401	1included	K562	TAF15

Showing 1 to 5 of 5 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

COPB1

General Information

Functions

Localization

Domains (AlphaFold: COPB1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for COPB1 is not avaliable on ENCORE database.

48 proteins are bound to COPB1 RNA:

eCLIP assay for COPB1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for COPB1 is not available on ENCORE database.

99 RBPs can affect the gene expression of COPB1 :

The Knockdown/knockout RNA-Seq assay for COPB1 is not available on ENCORE database.

2 RBPs can affect the splicing of COPB1 :

The Knockdown/knockout RNA-Seq assay for COPB1 is not avaliable on ENCORE database.