CENPI

General Information

Gene Name       : CENPI
Gene ID             : ENSG00000102384.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CENPI)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CENPIENSG00000102384.1311.7113.2712.49ENCSR000AEF
HepG2CENPIENSG00000102384.138.6211.5410.08ENCSR985KAT
K562CENPIENSG00000102384.139.1910.019.60ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq CENPI-BGKcLV08-K562ENCSR242VKRCENPIK562ReleasedENCSR015KGT   CRISPRKD% = 94.6,80.7
knockdown followed by RNA-seq CENPI-BGHcLV09-HepG2ENCSR603TOCCENPIHepG2ReleasedENCSR300EBW   CRISPRKD% = 77.3,75.0






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
CENPIENCAB545QJUA303-374A1BGHcLV09-3, Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
CENPIK562CRISPRBGKcLV06-7,BGKcLV06-8BGKcLV06-1,BGKcLV06-20.0,0.0NotSatisfiedENCODE3
CENPIK562CRISPRENCSR242VKRENCSR015KGTCENPI-BGKcLV08-7,CENPI-BGKcLV08-8NT-BGKcLV08-1,NT-BGKcLV08-294.6,80.7ReleasedENCODE4
CENPIK562CRISPRBGKcLV08-9,BGKcLV08-10BGKcLV08-1,BGKcLV08-290.2,82.0NotSatisfiedENCODE4
CENPIHepG2CRISPRBGHcLV07-7,BGHcLV07-8BGHcLV07-1,BGHcLV07-20.0,0.0NotSatisfiedENCODE3
CENPIHepG2CRISPRENCSR603TOCENCSR300EBWCENPI-BGHcLV09-3,CENPI-BGHcLV09-4NT-BGHcLV09-1,NT-BGHcLV09-277.3,75.0ReleasedENCODE4
CENPIHepG2CRISPRBGHcLV10-7,BGHcLV10-8BGHcLV10-1,BGHcLV10-272.8,74.3NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
CENPIProduct_ID: A303-374A
Lot_ID: 1
Source: Bethyl Labs
Target Name: CENPI-human		 CENPI-HEPG2-CRISPR.png<br>Caption: Western blot following CRISPR against CENPI in HepG2 whole cell lysate using CENPI specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against CENPI. CENPI protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for CENPI is not avaliable on ENCORE database.



Proteins bound to RNA
  • CENPI RNA is bound by 10 proteins.  







eCLIP assay for CENPI is not avaliable on ENCORE database.





10 proteins are bound to CENPI RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX100418580100418640+3'-UTR4.613715.22159K562SND1
chrX100396097100396253+3'-UTR,intron-Distal3.623975.14864K562KHSRP
chrX100353782100353835+5'-UTR,intron-Distal,intron-Proximal4.633845.05488HepG2QKI
chrX100353358100353447+5'-UTR,intron-Proximal4.838266.57024HepG2AQR
chrX100353354100353479+5'-UTR,intron-Proximal4.6620417.76861K562AQR
chrX100353619100353730+5'-UTR,intron-Distal,intron-Proximal3.487974.01234HepG2HNRNPL
chrX100353187100353253+5'-UTR,intron-Proximal3.174334.47655HepG2NCBP2
chrX100382171100382256+CDS,intron-Proximal3.190924.03389K562ZNF622
chrX100356121100356277+CDS3.416258.93089K562ZNF622
chrX100387437100387494+CDS,intron-Proximal4.176913.02181K562PRPF8
chrX100355913100356010+intron-Distal,intron-Proximal4.904918.24653K562KHSRP
chrX100354119100354160+intron-Distal3.901057.55880K562PTBP1
chrX100353837100353915+intron-Distal,intron-Proximal3.852545.57156HepG2QKI
chrX100381851100381936+intron-Distal,intron-Proximal3.910713.24603K562KHSRP
chrX100354049100354112+intron-Distal5.114808.39565HepG2PTBP1
chrX100354112100354160+intron-Distal4.893596.42900HepG2PTBP1
chrX100378924100378996+intron-Distal4.570895.97091K562TARDBP
chrX100354046100354107+intron-Distal5.1282412.87466K562PTBP1
chrX100355846100355913+intron-Distal3.486544.08064K562KHSRP
chrX100400956100401057+intron-Distal,intron-Proximal3.015466.02054K562KHSRP
chrX100353284100353354+intron-Distal,intron-Proximal5.681378.83608K562AQR
chrX100405897100406015+intron-Distal5.272389.71026K562TARDBP
chrX100405176100405270+intron-Distal4.138837.82201HepG2QKI
chrX100406869100407029+intron-Distal3.708163.14791K562HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CENPI is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CENPI is not available on ENCORE database.

  • 134 RBPs can affect the levels of CENPI.  








The Knockdown/knockout RNA-Seq assay for CENPI is not available on ENCORE database.





134 RBPs can affect the gene expression of CENPI :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CENPIENSG00000102384.9214.51610303.73080-0.501703.156202.51380HepG2ACO1
CENPIENSG00000102384.990.11270245.82790-1.447809.019608.12090HepG2AKAP1
CENPIENSG00000102384.9212.67300305.17790-0.521003.247102.42310HepG2AKAP8L
CENPIENSG00000102384.950.08440203.40240-2.0219014.6452012.97950HepG2ASCC1
CENPIENSG00000102384.9193.37040328.50900-0.764606.292905.32460HepG2AUH
CENPIENSG00000102384.9160.65710313.67800-0.965305.139803.85900HepG2BCCIP
CENPIENSG00000102384.9118.41830272.59300-1.202907.596406.19520HepG2BCLAF1
CENPIENSG00000102384.919.89830206.21920-3.3735029.6848028.08480HepG2BOP1
CENPIENSG00000102384.9194.18770309.98630-0.674804.210403.28350HepG2CALR
CENPIENSG00000102384.9115.03710193.24620-0.748303.143502.32120HepG2CIRBP
CENPIENSG00000102384.984.97910303.68900-1.8374024.8206023.27900HepG2CKAP4
CENPIENSG00000102384.9121.97440189.31890-0.634202.418201.76950HepG2CPSF6
CENPIENSG00000102384.9152.03820255.56610-0.749304.077402.74800HepG2CPSF7
CENPIENSG00000102384.9159.08860243.22550-0.612503.296602.18420HepG2YBX3
CENPIENSG00000102384.9224.77160395.26730-0.814407.752806.77830HepG2CELF1
CENPIENSG00000102384.9170.84370280.91860-0.717505.749204.60570HepG2DDX19B
CENPIENSG00000102384.9127.22640222.74630-0.808004.349303.51850HepG2DDX21
CENPIENSG00000102384.962.03110235.48560-1.9246015.1030013.75620HepG2DDX3X
CENPIENSG00000102384.9134.05430308.39420-1.202007.420906.22540HepG2DDX55
CENPIENSG00000102384.9134.81630214.98600-0.673202.188001.32260HepG2DDX59
CENPIENSG00000102384.944.51940202.28450-2.1839015.0924013.80670HepG2DDX6
CENPIENSG00000102384.9135.82010238.86360-0.814505.239304.30060HepG2DNAJC21
CENPIENSG00000102384.9117.54230236.70450-1.009906.695305.74300HepG2DNAJC2
CENPIENSG00000102384.9102.00080205.03450-1.007305.094603.58780HepG2AGO1
CENPIENSG00000102384.972.92940194.46350-1.414908.312307.32300HepG2EIF2S1
CENPIENSG00000102384.960.16740162.82820-1.436306.093004.78790HepG2EIF3D
CENPIENSG00000102384.9234.06610419.30040-0.841108.659607.33280HepG2EIF4G1
CENPIENSG00000102384.9259.97530401.66620-0.627604.106103.12570HepG2EIF4G2
CENPIENSG00000102384.9135.24450377.15650-1.4796018.5213017.19600HepG2ETF1
CENPIENSG00000102384.9213.89650296.82070-0.472702.346101.57800HepG2EWSR1
CENPIENSG00000102384.9115.13280212.21820-0.882204.912903.45290HepG2FASTKD2
CENPIENSG00000102384.9195.93920313.38110-0.677502.992502.19380HepG2FIP1L1
CENPIENSG00000102384.989.34540189.64670-1.085803.129602.04780HepG2FTO
CENPIENSG00000102384.9383.91930216.827700.824205.574604.61440HepG2FXR1
CENPIENSG00000102384.9147.28030289.99060-0.977409.227407.57920HepG2HDGF
CENPIENSG00000102384.9138.43540241.15140-0.800704.086103.32390HepG2HNRNPA1
CENPIENSG00000102384.9267.20520390.60490-0.547803.982902.89460HepG2HNRNPA2B1
CENPIENSG00000102384.999.28460268.21980-1.4338010.980009.67880HepG2HNRNPC
CENPIENSG00000102384.9126.92560181.41280-0.515302.021001.40130HepG2HNRNPF
CENPIENSG00000102384.9140.77450203.66950-0.532801.898101.31390HepG2HNRNPK
CENPIENSG00000102384.9216.32830387.17640-0.839808.652307.52500HepG2HNRNPL
CENPIENSG00000102384.9169.36660266.44770-0.653704.240303.50280HepG2HNRNPU
CENPIENSG00000102384.9316.90840204.456500.632203.209002.48790HepG2IGF2BP2
CENPIENSG00000102384.9143.81510272.17040-0.920306.567205.48510HepG2ILF2
CENPIENSG00000102384.9128.8747075.963500.762502.528601.40190HepG2KHDRBS1
CENPIENSG00000102384.9208.01090277.66310-0.416702.293001.36290HepG2KIF1C
CENPIENSG00000102384.9186.72590348.32510-0.899504.811903.70540HepG2LARP4
CENPIENSG00000102384.9186.27600294.28240-0.659803.590202.29500HepG2LARP7
CENPIENSG00000102384.9193.98110309.02640-0.671803.714302.30560HepG2LIN28B
CENPIENSG00000102384.989.69230170.43110-0.926102.280401.32330HepG2METAP2
CENPIENSG00000102384.9133.36060212.96350-0.675303.316401.98160HepG2NAA15
CENPIENSG00000102384.9171.82320266.09580-0.631003.259701.72580HepG2NIP7
CENPIENSG00000102384.9332.82350421.45800-0.340601.943601.30180HepG2NOL12
CENPIENSG00000102384.9128.49700283.10370-1.139605.265103.73170HepG2NONO
CENPIENSG00000102384.9159.56700263.75830-0.725104.836903.75400HepG2PARN
CENPIENSG00000102384.978.72140259.98900-1.7236013.0328011.03790HepG2PCBP2
CENPIENSG00000102384.9173.74560282.40400-0.700803.487501.60630HepG2PHF6
CENPIENSG00000102384.9159.93820237.65300-0.571302.356201.67100HepG2PPIL4
CENPIENSG00000102384.957.03370237.99000-2.0610015.9475014.23080HepG2PRPF8
CENPIENSG00000102384.9164.11310402.31270-1.2936013.9531012.75540HepG2PUF60
CENPIENSG00000102384.9170.30340427.06590-1.3264020.1801018.87610HepG2PUM1
CENPIENSG00000102384.9215.76340426.75820-0.984009.958708.72850HepG2PUM2
CENPIENSG00000102384.9386.60070309.373100.321401.863701.33680HepG2PUS1
CENPIENSG00000102384.9111.04850250.84590-1.175605.331604.37020HepG2RAVER1
CENPIENSG00000102384.9143.80670309.21510-1.1045010.072608.57900HepG2RBM15
CENPIENSG00000102384.979.46310315.23630-1.9881023.7329022.51450HepG2RBM22
CENPIENSG00000102384.9171.01830354.85270-1.053108.290106.56700HepG2RBM27
CENPIENSG00000102384.9186.6328076.979301.277605.517603.37970HepG2RBM47
CENPIENSG00000102384.9315.58830213.471400.563901.989501.51450HepG2NELFE
CENPIENSG00000102384.9295.45880198.773700.571702.520701.92890HepG2RECQL
CENPIENSG00000102384.925.58440195.40960-2.9332024.4945022.88770HepG2RPLP0
CENPIENSG00000102384.9104.72430246.49760-1.235007.092005.63370HepG2RPS10
CENPIENSG00000102384.933.64650158.41670-2.2352011.8483010.68110HepG2RPS19
CENPIENSG00000102384.9116.43610327.27540-1.4910013.6767011.99460HepG2RPS2
CENPIENSG00000102384.944.9091080.05020-0.833901.977601.30170HepG2RPS3A
CENPIENSG00000102384.9186.33350334.06950-0.842305.535104.00080HepG2RPS5
CENPIENSG00000102384.935.31230235.43010-2.7371022.5732020.74340HepG2RRP9
CENPIENSG00000102384.9139.84820237.29320-0.762804.954104.13450HepG2SAFB2
CENPIENSG00000102384.9122.86150338.75030-1.4632012.1453010.67400HepG2SF3A3
CENPIENSG00000102384.996.45080202.70920-1.071505.850304.85800HepG2SF3B1
CENPIENSG00000102384.9263.71090385.74120-0.548704.330303.48090HepG2SLBP
CENPIENSG00000102384.9179.00890276.74050-0.628503.856203.11770HepG2SMN1
CENPIENSG00000102384.9114.08020256.03360-1.166307.407405.79100HepG2SMNDC1
CENPIENSG00000102384.954.29160225.55040-2.0547012.7575011.09560HepG2SNRNP70
CENPIENSG00000102384.951.59140356.05370-2.7869043.9633042.59360HepG2SRFBP1
CENPIENSG00000102384.9322.87310208.457700.631103.526203.00870HepG2SRSF1
CENPIENSG00000102384.994.68530218.12310-1.203905.931304.42110HepG2SRSF3
CENPIENSG00000102384.9229.41170397.21710-0.792007.576706.60940HepG2SRSF5
CENPIENSG00000102384.964.83640178.22820-1.4588010.162008.97400HepG2SRSF7
CENPIENSG00000102384.982.71200169.57220-1.035703.304002.71150HepG2SRSF9
CENPIENSG00000102384.9467.87830309.149100.597705.715305.02940HepG2SSB
CENPIENSG00000102384.9138.05060209.30150-0.600402.770301.53290HepG2STAU1
CENPIENSG00000102384.9132.94050234.43500-0.818403.069601.80000HepG2SUB1
CENPIENSG00000102384.9301.07040451.75220-0.585405.413204.59600HepG2SUCLG1
CENPIENSG00000102384.937.0094088.75330-1.261903.734202.17090HepG2SUGP2
CENPIENSG00000102384.9117.71580211.59470-0.846003.780002.69400HepG2SUPT6H
CENPIENSG00000102384.9157.17210307.02750-0.966005.158404.28040HepG2SUPV3L1
CENPIENSG00000102384.9276.63710187.308000.562502.451601.92000HepG2TAF15
CENPIENSG00000102384.970.75510199.62860-1.496409.384208.16500HepG2TARDBP
CENPIENSG00000102384.969.18650205.80540-1.572708.701907.13120HepG2TFIP11
CENPIENSG00000102384.964.59720258.96590-2.0032017.2015016.14870HepG2TIAL1
CENPIENSG00000102384.9102.24700261.21410-1.3532010.239109.25940HepG2TRIM56
CENPIENSG00000102384.9269.44350393.03140-0.544703.401902.42210HepG2TUFM
CENPIENSG00000102384.974.22910268.06700-1.8525016.3505014.77370HepG2U2AF1
CENPIENSG00000102384.937.77110248.81150-2.719707.071605.42010HepG2U2AF2
CENPIENSG00000102384.9257.74450416.01020-0.690703.609902.64740HepG2UBE2L3
CENPIENSG00000102384.971.21640181.38820-1.348807.726006.45850HepG2UCHL5
CENPIENSG00000102384.9102.24790300.42130-1.5549018.1132016.63250HepG2UPF1
CENPIENSG00000102384.9167.96250308.77940-0.878407.213905.60880HepG2UTP18
CENPIENSG00000102384.9137.43030290.04260-1.077608.653807.68900HepG2UTP3
CENPIENSG00000102384.9184.05380275.91240-0.584102.419801.42970HepG2XRCC6
CENPIENSG00000102384.9279.89970164.732100.764705.784904.86930HepG2ZC3H8
CENPIENSG00000102384.958.17550330.40370-2.5057034.9865033.60600HepG2ZNF622
CENPIENSG00000102384.9242.07020333.96930-0.464302.614802.05970K562AGGF1
CENPIENSG00000102384.9306.59840736.25160-1.2638016.3416015.07340K562AQR
CENPIENSG00000102384.999.28410161.44900-0.701402.871001.79390K562CCAR1
CENPIENSG00000102384.9813.828301007.05790-0.307402.334301.43880K562CELF1
CENPIENSG00000102384.9307.37460522.22950-0.764708.879407.79460K562DDX47
CENPIENSG00000102384.9239.44520334.39660-0.481903.050201.65890K562DDX6
CENPIENSG00000102384.9283.42150373.95180-0.399902.270401.48780K562DKC1
CENPIENSG00000102384.9109.31990173.61970-0.667402.758701.41680K562DNAJC21
CENPIENSG00000102384.9196.17050357.86290-0.867306.073304.67560K562EFTUD2
CENPIENSG00000102384.979.50230164.22900-1.046603.560502.40450K562EIF3A
CENPIENSG00000102384.9224.72180383.19890-0.770004.648603.26730K562EIF3D
CENPIENSG00000102384.9263.23280382.57430-0.539403.929502.98900K562EIF3G
CENPIENSG00000102384.9187.83360344.57690-0.875407.014005.71320K562EIF4A3
CENPIENSG00000102384.9556.24970819.01120-0.558206.136804.75230K562EIF4G2
CENPIENSG00000102384.9537.69020376.424300.514302.715202.01670K562G3BP2
CENPIENSG00000102384.9246.30790358.77780-0.542602.699801.30390K562GEMIN5
CENPIENSG00000102384.9364.16770576.21520-0.662005.641504.55890K562GRSF1
CENPIENSG00000102384.9159.63450269.17130-0.753804.198203.47820K562HNRNPC
CENPIENSG00000102384.9336.71580476.66580-0.501403.030202.19870K562HSPD1
CENPIENSG00000102384.9352.56680510.14580-0.533003.976802.49210K562IGF2BP3
CENPIENSG00000102384.9109.23530205.35730-0.910703.352502.31460K562KRR1
CENPIENSG00000102384.9356.15240527.17340-0.565804.669103.57110K562MAGOH
CENPIENSG00000102384.9201.91020352.52300-0.804005.123903.21740K562NONO
CENPIENSG00000102384.9318.46500441.76700-0.472203.715402.86530K562NSUN2
CENPIENSG00000102384.9341.75170469.07330-0.456902.791001.80710K562PCBP2
CENPIENSG00000102384.9216.83910348.24090-0.683503.796002.91820K562PRPF8
CENPIENSG00000102384.9578.76440893.60010-0.626706.074004.86690K562PUF60
CENPIENSG00000102384.9747.44570950.50490-0.346702.743401.68270K562PUM1
CENPIENSG00000102384.9684.99760931.28520-0.443104.548803.30850K562PUM2
CENPIENSG00000102384.9154.48820354.74880-1.199309.021907.53400K562RPS19
CENPIENSG00000102384.9292.75010435.94280-0.574504.691303.65240K562SF3A3
CENPIENSG00000102384.9266.45060391.47400-0.555003.983902.95200K562SF3B4
CENPIENSG00000102384.9359.93680502.08920-0.480203.234802.47470K562SRSF1
CENPIENSG00000102384.9338.70450474.15560-0.485303.122101.99620K562SRSF5
CENPIENSG00000102384.9220.84640337.21930-0.610603.055301.98510K562SUPV3L1
CENPIENSG00000102384.9298.83860508.17290-0.766006.562605.43120K562TARDBP
CENPIENSG00000102384.9313.65070490.18340-0.644205.329104.14030K562TIA1
CENPIENSG00000102384.9156.07590246.57360-0.659803.261102.21470K562TRIM56
CENPIENSG00000102384.9240.34050364.94380-0.602603.273302.06380K562U2AF1
CENPIENSG00000102384.9240.37820376.88580-0.648804.842303.78230K562U2AF2
CENPIENSG00000102384.9259.53060468.41650-0.851909.751008.50440K562UPF1
CENPIENSG00000102384.9289.71100416.81110-0.524804.283903.24780K562WDR43
CENPIENSG00000102384.9247.50160363.36830-0.554002.987001.71210K562XRN2
CENPIENSG00000102384.9643.83710829.40550-0.365402.630301.79300K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CENPI is not available on ENCORE database.





3 RBPs can affect the splicing of CENPI :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECENPIENSG00000102384.9chrX+100354797100355054100353432100353528100356046100356284-0.365000.000600.01368excludedK562SRSF1
SECENPIENSG00000102384.9chrX+100416516100416558100402931100403150100417821100418425-0.161000.000650.08007excludedK562DROSHA
SECENPIENSG00000102384.9chrX+100354797100355054100353432100353528100356046100356284-0.254000.000370.01143excludedHepG2SRSF1
A3SSCENPIENSG00000102384.9chrX+1003871531003872961003871781003872961003849701003850620.051000.010310.05427longerK562AQR
A3SSCENPIENSG00000102384.9chrX+1003644451003645801003644611003645801003572621003574000.228000.000140.00122longerK562AQR
A3SSCENPIENSG00000102384.9chrX+1003824431003826541003824861003826541003821261003822550.061000.019980.09530longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CENPI is not avaliable on ENCORE database.