C21orf58

General Information

Gene Name       : C21orf58
Gene ID             : ENSG00000160298.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C21orf58)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878C21orf58ENSG00000160298.170.824.562.69ENCSR000AEF
HepG2C21orf58ENSG00000160298.175.441.903.67ENCSR985KAT
K562C21orf58ENSG00000160298.1711.667.139.39ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C21orf58 is not avaliable on ENCORE database.



Proteins bound to RNA
  • C21orf58 RNA is bound by 27 proteins.  







eCLIP assay for C21orf58 is not avaliable on ENCORE database.





27 proteins are bound to C21orf58 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr214772132447721381-3'-UTR,intron-Distal3.631543.04470K562FUS
chr214773858747738740-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.717379.87426K562HNRNPK
chr214772168847721765-3'-UTR,intron-Distal3.187903.95743K562AKAP8L
chr214773473247734795-3'-UTR,CDS,intron-Distal,intron-Proximal3.310193.99124HepG2PPIG
chr214772116947721226-3'-UTR,intron-Distal3.922713.05053K562DROSHA
chr214772114747721231-3'-UTR,intron-Distal3.108283.60267K562FUS
chr214772138147721496-3'-UTR,intron-Distal3.574686.17457K562FUS
chr214773538847735459-3'-UTR,5'-UTR,CDS,intron-Distal4.252895.80295HepG2PPIG
chr214773861547738694-5'-UTR,intron-Distal,intron-Proximal3.983415.65933HepG2DDX59
chr214774368847743721-5'-UTR,intron-Distal3.364373.04831K562RBM15
chr214774286047742906-5'-UTR,intron-Distal4.816846.57313K562RBM15
chr214774311747743183-5'-UTR,intron-Distal3.282506.56546K562RBM15
chr214774334547743382-5'-UTR,intron-Distal3.909843.04254K562UCHL5
chr214774303647743075-5'-UTR,intron-Distal3.720087.09919K562RBM15
chr214774324747743279-5'-UTR,intron-Distal3.518884.22460K562RBM15
chr214773846047738587-5'-UTR,intron-Distal5.398907.95752K562HNRNPK
chr214774363847743741-5'-UTR,intron-Distal4.326435.47892K562DDX3X
chr214774277847742833-5'-UTR,intron-Distal5.341379.33028K562RBM15
chr214773848147738605-5'-UTR,intron-Distal,intron-Proximal3.171425.96194HepG2PCBP2
chr214773457747734638-CDS,intron-Distal,intron-Proximal3.567224.00200K562EIF4G2
chr214773145747731568-CDS,intron-Distal,intron-Proximal4.4662518.31691K562SF3B4
chr214772237947722444-CDS,intron-Distal,intron-Proximal3.843604.68902HepG2PPIG
chr214773146047731588-CDS,intron-Distal,intron-Proximal3.597213.48391K562SMNDC1
chr214773143947731632-CDS,intron-Distal,intron-Proximal4.4944625.41171K562FAM120A
chr214773144547731618-CDS,intron-Distal,intron-Proximal5.5538323.01577K562GTF2F1
chr214773142547731560-CDS,intron-Distal,intron-Proximal3.128183.93367K562BUD13
chr214772244447722492-CDS,intron-Distal,intron-Proximal4.849945.86613HepG2PPIG
chr214772241647722487-CDS,intron-Distal3.720985.21950K562DDX24
chr214773146547731583-CDS,intron-Distal,intron-Proximal3.591504.77785K562RBFOX2
chr214773144447731555-CDS,intron-Distal,intron-Proximal3.399574.50097K562FUS
chr214773171447731780-intron-Distal5.417637.03699K562GTF2F1
chr214773267747732772-intron-Distal3.676516.94888K562EWSR1
chr214773266347732713-intron-Distal3.232363.29111K562FAM120A
chr214773265247732776-intron-Distal3.816849.25963K562CSTF2T
chr214773369347733796-intron-Distal3.8875310.74936K562FAM120A
chr214773265547732772-intron-Distal3.433823.22046K562AKAP8L
chr214773183847731872-intron-Distal4.615983.72755K562EIF4G2
chr214773150647731582-intron-Distal,intron-Proximal5.3798219.64888K562CSTF2T
chr214773450147734582-intron-Distal,intron-Proximal3.775827.33509K562EFTUD2
chr214773372347733872-intron-Distal3.760557.28329K562FUS
chr214773341447733468-intron-Distal3.159043.15535K562EWSR1
chr214773366347733825-intron-Distal3.622329.94105K562EWSR1
chr214773150847731594-intron-Distal,intron-Proximal5.133976.03756HepG2FAM120A
chr214772208847722142-intron-Distal,intron-Proximal4.022203.58113K562EWSR1
chr214773181347731860-intron-Distal4.103716.80849K562FAM120A
chr214773176547731868-intron-Distal5.007804.57154HepG2FAM120A
chr214773177047731859-intron-Distal4.271674.13104K562APOBEC3C
chr214773266247732769-intron-Distal3.742664.96298K562GTF2F1
chr214773372847733824-intron-Distal4.088705.93121K562FTO
chr214773180747731863-intron-Distal4.580295.62460K562CSTF2T
chr214773180747731871-intron-Distal5.011166.78005K562FASTKD2
chr214773208047732118-intron-Distal3.612493.41462K562EWSR1
chr214773151247731622-intron-Distal,intron-Proximal4.6076010.76744K562EWSR1
chr214773182047731869-intron-Distal4.592413.86024K562EWSR1
chr214773163747731678-intron-Distal,intron-Proximal4.419324.94603K562CSTF2T
chr214773150147731590-intron-Distal,intron-Proximal4.603996.14250K562DROSHA
chr214773151547731673-intron-Distal,intron-Proximal7.4085631.45845K562EIF4G2
chr214773172047731791-intron-Distal4.692723.58113K562EWSR1
chr214773784847737926-intron-Distal,intron-Proximal4.078858.79285K562AQR
chr214773180447731870-intron-Distal5.424543.77360K562GTF2F1
chr214773174347731811-intron-Distal4.467278.98738K562FAM120A
chr214773176947731867-intron-Distal5.083373.72302K562FTO
chr214773451047734574-intron-Distal,intron-Proximal4.011883.19482K562AKAP8L
chr214772350547723599-intron-Distal3.297374.09735K562ILF3
chr214773148647731584-intron-Distal,intron-Proximal4.763327.60571K562FTO
chr214773373647733823-intron-Distal3.460599.02184K562CSTF2T
chr214773787547737917-intron-Distal,intron-Proximal3.428163.47285K562PRPF8
chr214773152147731576-intron-Distal,intron-Proximal3.399976.20002K562FASTKD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C21orf58 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C21orf58 is not available on ENCORE database.

  • 113 RBPs can affect the levels of C21orf58.  








The Knockdown/knockout RNA-Seq assay for C21orf58 is not available on ENCORE database.





113 RBPs can affect the gene expression of C21orf58 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C21orf58ENSG00000160298.1382.79550199.75540-1.270609.829408.82720HepG2ACO1
C21orf58ENSG00000160298.13129.4814070.305600.880903.344302.25530HepG2ADAR
C21orf58ENSG00000160298.1332.7353080.88530-1.305003.307702.73310HepG2AKAP1
C21orf58ENSG00000160298.13108.71160200.71670-0.884705.436604.39510HepG2AKAP8L
C21orf58ENSG00000160298.1315.8837066.92510-2.075005.999704.86620HepG2ASCC1
C21orf58ENSG00000160298.13106.41550207.03910-0.960206.047705.09490HepG2AUH
C21orf58ENSG00000160298.1310.74830131.19390-3.609507.293006.37550HepG2BOP1
C21orf58ENSG00000160298.1337.35210146.57200-1.9723011.6396010.23510HepG2CALR
C21orf58ENSG00000160298.13385.68750198.944100.955006.103404.62960HepG2CCAR1
C21orf58ENSG00000160298.1329.7932063.58360-1.093702.350701.63350HepG2CIRBP
C21orf58ENSG00000160298.1363.99360199.73930-1.6421014.4225013.15360HepG2CKAP4
C21orf58ENSG00000160298.13108.55520157.43870-0.536402.023101.45700HepG2CELF1
C21orf58ENSG00000160298.13128.34980184.75770-0.525602.251901.49450HepG2DDX19B
C21orf58ENSG00000160298.1360.56020103.77350-0.777002.313101.68540HepG2DDX21
C21orf58ENSG00000160298.1348.48460101.50150-1.065903.694802.62900HepG2DDX24
C21orf58ENSG00000160298.1326.5665077.48050-1.544204.540303.75390HepG2DDX3X
C21orf58ENSG00000160298.1359.06870136.76240-1.211202.251601.37280HepG2DDX59
C21orf58ENSG00000160298.1320.3501066.56080-1.709604.243403.49150HepG2DDX6
C21orf58ENSG00000160298.13118.6662070.176200.757802.988902.31590HepG2DNAJC2
C21orf58ENSG00000160298.1326.4946095.51900-1.850107.418705.64390HepG2AGO1
C21orf58ENSG00000160298.1322.4601063.98310-1.510303.583402.91290HepG2EIF2S1
C21orf58ENSG00000160298.1340.11360123.00920-1.616604.933103.75250HepG2EIF3D
C21orf58ENSG00000160298.1397.87780167.01370-0.770903.689702.74660HepG2EIF4G1
C21orf58ENSG00000160298.13194.5685071.345601.447308.660807.49550HepG2FXR1
C21orf58ENSG00000160298.13111.5936066.180900.753702.230401.63010HepG2G3BP1
C21orf58ENSG00000160298.13137.0568070.262900.963803.551302.53670HepG2G3BP2
C21orf58ENSG00000160298.13130.50830190.72580-0.547402.655501.69560HepG2HDGF
C21orf58ENSG00000160298.13247.2080079.498201.636603.893203.08130HepG2HNRNPC
C21orf58ENSG00000160298.13135.0030078.972300.773503.212702.56300HepG2HNRNPU
C21orf58ENSG00000160298.1319.8427067.27050-1.761404.921904.04440HepG2IGF2BP2
C21orf58ENSG00000160298.13121.9916047.703101.354505.734103.92720HepG2KHDRBS1
C21orf58ENSG00000160298.13143.0726067.664301.080203.130402.05500HepG2KHSRP
C21orf58ENSG00000160298.13109.33300210.27690-0.943602.446601.66900HepG2LARP4
C21orf58ENSG00000160298.13180.0953071.370501.335307.171506.13160HepG2MAGOH
C21orf58ENSG00000160298.1346.77250128.71910-1.460504.466003.14750HepG2METAP2
C21orf58ENSG00000160298.13247.14680167.888300.557802.736601.97690HepG2NOL12
C21orf58ENSG00000160298.13100.9010044.509701.180603.282401.70040HepG2NOLC1
C21orf58ENSG00000160298.1331.1540065.41700-1.070302.431701.75080HepG2PABPC4
C21orf58ENSG00000160298.13150.3549070.436201.093905.929904.88210HepG2PPIL4
C21orf58ENSG00000160298.1325.0669062.73370-1.323502.901502.07460HepG2PRPF8
C21orf58ENSG00000160298.13108.54010160.25660-0.562202.025701.50360HepG2PUF60
C21orf58ENSG00000160298.13108.51120169.99190-0.647602.685002.02400HepG2PUM2
C21orf58ENSG00000160298.1327.89350102.67960-1.880102.244601.60480HepG2RAVER1
C21orf58ENSG00000160298.13114.07450282.41370-1.3078010.949609.41720HepG2RBM15
C21orf58ENSG00000160298.1316.57040198.69630-3.5839032.9674031.56740HepG2RBM22
C21orf58ENSG00000160298.13212.4794084.216901.335008.865907.99800HepG2NELFE
C21orf58ENSG00000160298.13224.1538078.427601.5150011.8826010.73910HepG2RECQL
C21orf58ENSG00000160298.1321.0252099.40760-2.241209.760708.60930HepG2RPLP0
C21orf58ENSG00000160298.1320.76280119.72290-2.527608.681207.66550HepG2RPS19
C21orf58ENSG00000160298.1351.84870108.88980-1.070503.757502.82950HepG2RPS2
C21orf58ENSG00000160298.1312.2135062.05720-2.345106.086604.96930HepG2RRP9
C21orf58ENSG00000160298.13137.2110070.325900.964204.519703.73020HepG2SAFB2
C21orf58ENSG00000160298.1348.23860120.11380-1.316103.499302.43830HepG2SERBP1
C21orf58ENSG00000160298.1394.32840269.26220-1.5132011.9076010.45030HepG2SF3A3
C21orf58ENSG00000160298.1351.09870128.90580-1.335002.191301.55880HepG2SF3B1
C21orf58ENSG00000160298.1344.10290224.41090-2.3472024.0955022.99600HepG2SRFBP1
C21orf58ENSG00000160298.13104.96560158.21950-0.592002.389701.80270HepG2SRSF5
C21orf58ENSG00000160298.1352.2173090.65180-0.795802.343501.69880HepG2SRSF7
C21orf58ENSG00000160298.1333.4334066.90040-1.000702.619302.07870HepG2SRSF9
C21orf58ENSG00000160298.1322.7419080.94940-1.831705.169404.28990HepG2SUPV3L1
C21orf58ENSG00000160298.1329.8485076.72090-1.362004.333203.73630HepG2TIAL1
C21orf58ENSG00000160298.1357.10000188.95680-1.726502.539001.93480HepG2U2AF1
C21orf58ENSG00000160298.1327.82410122.59880-2.139505.558004.11520HepG2U2AF2
C21orf58ENSG00000160298.1381.24350238.79470-1.5554014.9067013.53450HepG2UPF1
C21orf58ENSG00000160298.13172.20760245.44490-0.511202.534101.52560HepG2UTP18
C21orf58ENSG00000160298.13127.24460230.54640-0.857505.586504.78410HepG2UTP3
C21orf58ENSG00000160298.13187.8428079.685701.237005.898904.85180HepG2XRN2
C21orf58ENSG00000160298.1340.24410262.62800-2.7062036.8293035.42550HepG2ZNF622
C21orf58ENSG00000160298.13289.61900510.10950-0.816704.390902.86450K562AARS
C21orf58ENSG00000160298.13575.684701642.48390-1.5125058.7010056.15690K562AGGF1
C21orf58ENSG00000160298.131419.007101804.72850-0.346903.144102.08160K562AKAP8
C21orf58ENSG00000160298.13618.406801709.05110-1.4666037.4015034.54750K562AKAP8L
C21orf58ENSG00000160298.131169.667701793.15350-0.6164011.523609.47660K562ATP5C1
C21orf58ENSG00000160298.13649.75550486.581700.417103.526802.43650K562BCLAF1
C21orf58ENSG00000160298.13781.58700499.532400.645706.175404.42800K562CCAR1
C21orf58ENSG00000160298.131596.422501962.94880-0.298203.107701.84690K562CCDC124
C21orf58ENSG00000160298.131297.69940886.051000.550408.468106.34850K562DDX21
C21orf58ENSG00000160298.13532.107601164.17270-1.1295030.0467028.12270K562DDX47
C21orf58ENSG00000160298.13879.50470559.262300.653103.867402.24700K562DHX30
C21orf58ENSG00000160298.13984.032901839.23590-0.9023021.7589018.94110K562DKC1
C21orf58ENSG00000160298.13667.45350495.512200.429603.857302.40540K562EIF2S1
C21orf58ENSG00000160298.13842.81310667.453300.336403.012402.26740K562EIF2S2
C21orf58ENSG00000160298.13340.78950508.09610-0.576202.325101.41110K562EIF3A
C21orf58ENSG00000160298.13198.31060285.75780-0.527002.956802.13450K562EIF3G
C21orf58ENSG00000160298.13844.24410630.352900.421403.623802.14710K562EXOSC5
C21orf58ENSG00000160298.13895.96080532.241800.751308.705907.10880K562FIP1L1
C21orf58ENSG00000160298.13321.37900484.89300-0.593402.721401.60640K562FKBP4
C21orf58ENSG00000160298.13336.47050490.18810-0.542903.612602.93600K562FXR1
C21orf58ENSG00000160298.1399.22570205.00960-1.046905.313604.26220K562G3BP2
C21orf58ENSG00000160298.131326.03860557.710001.2494026.4214024.65800K562HNRNPC
C21orf58ENSG00000160298.13193.17400357.12700-0.886503.276301.92040K562HNRNPK
C21orf58ENSG00000160298.13524.70830721.56430-0.459603.098202.25840K562HSPD1
C21orf58ENSG00000160298.13828.024001813.82790-1.1313012.7641010.59520K562KIF1C
C21orf58ENSG00000160298.13146.70220373.82980-1.349506.046304.60570K562KRR1
C21orf58ENSG00000160298.13248.50450540.66380-1.121506.166403.98560K562LARP7
C21orf58ENSG00000160298.13980.859201736.20060-0.823803.451602.20840K562MAK16
C21orf58ENSG00000160298.13645.17970375.079000.782408.375706.66950K562MATR3
C21orf58ENSG00000160298.13932.170702031.93180-1.1242016.1426013.70840K562MBNL1
C21orf58ENSG00000160298.131371.332901020.735600.425906.296905.11930K562MTPAP
C21orf58ENSG00000160298.13421.024201424.22850-1.7582018.4207015.53550K562NAA15
C21orf58ENSG00000160298.131548.159901134.116600.448909.129307.88120K562NSUN2
C21orf58ENSG00000160298.13132.15710216.73940-0.713703.351301.33250K562PABPC4
C21orf58ENSG00000160298.13315.65170987.40370-1.645306.506904.79580K562PABPN1
C21orf58ENSG00000160298.131753.74510801.804701.129004.097803.08390K562PCBP3
C21orf58ENSG00000160298.131233.42030614.995301.0039019.3126017.30980K562POLR2G
C21orf58ENSG00000160298.13791.93550604.243500.390202.724901.91070K562PPIG
C21orf58ENSG00000160298.13177.24380400.73190-1.1769010.704209.21500K562PRPF8
C21orf58ENSG00000160298.13905.269201388.57010-0.617203.796602.84480K562PUF60
C21orf58ENSG00000160298.13887.708201477.49750-0.735005.211403.71280K562PUM1
C21orf58ENSG00000160298.13346.846701695.10890-2.2890069.0816066.29400K562PUS1
C21orf58ENSG00000160298.1390.52550195.61150-1.111604.419702.56640K562RAVER1
C21orf58ENSG00000160298.13828.71310532.948700.636803.576601.37700K562RBFOX2
C21orf58ENSG00000160298.13504.017701651.46320-1.7122037.6852035.40960K562RBM15
C21orf58ENSG00000160298.13526.70530341.351000.625602.929801.49380K562RBM34
C21orf58ENSG00000160298.13157.46590408.09670-1.3739012.8303011.05120K562RPS19
C21orf58ENSG00000160298.13307.51250903.34730-1.554606.030604.04510K562SF1
C21orf58ENSG00000160298.13849.547801119.10190-0.397604.603603.57540K562SF3A3
C21orf58ENSG00000160298.13152.60570213.20840-0.482502.076101.33710K562SF3B4
C21orf58ENSG00000160298.13751.74990550.119500.450403.413601.99710K562SLBP
C21orf58ENSG00000160298.13469.819301036.90820-1.142104.399102.74000K562SNRNP200
C21orf58ENSG00000160298.13575.85970432.764100.412002.429101.48480K562SRFBP1
C21orf58ENSG00000160298.13773.86500383.096601.014308.460806.48620K562SRSF4
C21orf58ENSG00000160298.13961.65510790.662300.282402.501601.39270K562SRSF7
C21orf58ENSG00000160298.13342.50320616.87880-0.848909.259707.75120K562SYNCRIP
C21orf58ENSG00000160298.13608.21010362.323500.747205.641504.61100K562TARDBP
C21orf58ENSG00000160298.13700.63300349.524101.0032014.1051012.13490K562TIA1
C21orf58ENSG00000160298.13516.97750343.186500.591002.714601.63540K562TRA2A
C21orf58ENSG00000160298.1395.90990198.75970-1.051305.445903.80810K562U2AF1
C21orf58ENSG00000160298.13578.61860410.551400.494903.008001.93840K562UCHL5
C21orf58ENSG00000160298.131486.032501202.528900.305303.768902.94230K562UPF1
C21orf58ENSG00000160298.13842.462801718.46240-1.028403.014901.64460K562UTP18
C21orf58ENSG00000160298.13574.20540418.188500.457302.441501.32980K562XRN2
C21orf58ENSG00000160298.13573.915301220.66730-1.088804.032301.95000K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C21orf58 is not available on ENCORE database.





11 RBPs can affect the splicing of C21orf58 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEC21orf58ENSG00000160298.13chr21-477346294773479447731369477314814773538747735461-0.156000.000050.00309excludedK562AKAP8L
SEC21orf58ENSG00000160298.13chr21-477346294773479447731369477314814773538747735461-0.192000.000080.00203excludedK562PUS1
SEC21orf58ENSG00000160298.13chr21-477346294773479447731369477314814773538747735461-0.108000.002100.05932excludedK562UTP18
SEC21orf58ENSG00000160298.13chr21-4773668247736881477353874773546147737121477371820.137000.003490.07116includedK562AGGF1
A3SSC21orf58ENSG00000160298.13chr21-4772239847722536477223984772249047731369477314810.078000.000410.00311longerK562AQR
A3SSC21orf58ENSG00000160298.13chr21-4773462947734963477346294773479447735387477354750.250000.014530.07279longerK562AQR
RIC21orf58ENSG00000160298.13chr21-477347844773546147734784477349634773538747735461-0.337000.000040.00918excludedK562APOBEC3C
RIC21orf58ENSG00000160298.13chr21-477210434772206847721043477216274772191047722068-0.452000.000090.02074excludedK562DDX55
RIC21orf58ENSG00000160298.13chr21-477347844773546147734784477349634773538747735461-0.413000.000000.00006excludedK562EIF4G2
RIC21orf58ENSG00000160298.13chr21-477347844773546147734784477349634773538747735461-0.237000.001320.08296excludedK562ZC3H8
RIC21orf58ENSG00000160298.13chr21-4772104347722068477210434772162747721910477220680.089000.013430.06978includedK562AQR
RIC21orf58ENSG00000160298.13chr21-477347844773546147734784477349634773538747735461-0.465000.000810.03208excludedK562TARDBP
RIC21orf58ENSG00000160298.13chr21-477347844773546147734784477349634773538747735461-0.499000.000040.00132excludedK562FXR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for C21orf58 is not avaliable on ENCORE database.