TUBE1

General Information

Gene Name       : TUBE1
Gene ID             : ENSG00000074935.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TUBE1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TUBE1ENSG00000074935.137.979.138.55ENCSR000AEF
HepG2TUBE1ENSG00000074935.1310.5215.6313.07ENCSR985KAT
K562TUBE1ENSG00000074935.1321.8420.6921.27ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TUBE1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TUBE1 RNA is bound by 7 proteins.  







eCLIP assay for TUBE1 is not avaliable on ENCORE database.





7 proteins are bound to TUBE1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6112397663112397723-3'-UTR,CDS,intron-Distal,intron-Proximal4.878168.65151HepG2U2AF2
chr6112397299112397363-3'-UTR,CDS,intron-Distal,intron-Proximal3.230563.66791K562U2AF1
chr6112393960112394090-3'-UTR,CDS,intron-Distal,intron-Proximal4.952036.13315HepG2BCLAF1
chr6112397517112397591-3'-UTR,CDS,intron-Distal,intron-Proximal3.950115.65086HepG2BCLAF1
chr6112397630112397734-3'-UTR,CDS,intron-Distal,intron-Proximal3.502777.50495K562BUD13
chr6112396018112396064-3'-UTR,CDS,intron-Distal,intron-Proximal4.305633.79000HepG2U2AF2
chr6112397346112397380-3'-UTR,CDS,intron-Distal,intron-Proximal4.505316.14774K562U2AF2
chr6112397255112397383-3'-UTR,CDS,intron-Distal,intron-Proximal4.8590924.61138HepG2U2AF2
chr6112397269112397346-3'-UTR,CDS,intron-Distal,intron-Proximal4.0569211.75068K562U2AF2
chr6112397653112397724-3'-UTR,CDS,intron-Distal,intron-Proximal5.4506712.56491K562U2AF2
chr6112397467112397536-3'-UTR,CDS,intron-Distal,intron-Proximal3.514574.44627K562KHSRP
chr6112402306112402403-3'-UTR,5'-UTR,CDS,intron-Distal3.620837.05173K562ZNF622
chr6112408469112408539-CDS,intron-Distal,intron-Proximal4.747893.45799HepG2U2AF2
chr6112408388112408438-CDS,intron-Distal,intron-Proximal4.933746.59451HepG2PRPF8
chr6112400714112400809-intron-Distal,intron-Proximal3.419623.18246K562PRPF8
chr6112397427112397497-intron-Distal,intron-Proximal4.349203.20552HepG2KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TUBE1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TUBE1 is not available on ENCORE database.

  • 115 RBPs can affect the levels of TUBE1.  








The Knockdown/knockout RNA-Seq assay for TUBE1 is not available on ENCORE database.





115 RBPs can affect the gene expression of TUBE1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TUBE1ENSG00000074935.9152.30560252.02030-0.726604.944304.17670HepG2ACO1
TUBE1ENSG00000074935.9430.89190318.620700.435401.846101.40190HepG2AKAP1
TUBE1ENSG00000074935.9187.50970263.62770-0.491501.996401.32500HepG2ASCC1
TUBE1ENSG00000074935.9497.32110292.273700.766805.867203.91940HepG2ATP5C1
TUBE1ENSG00000074935.9351.54350504.85160-0.522204.643003.79410HepG2AUH
TUBE1ENSG00000074935.9365.10290273.566200.416302.245801.54600HepG2CALR
TUBE1ENSG00000074935.9496.52200344.290600.528102.652201.70150HepG2CCAR1
TUBE1ENSG00000074935.9365.91020250.465800.546802.840202.05650HepG2CIRBP
TUBE1ENSG00000074935.9308.43890408.32470-0.404701.908101.32600HepG2CPSF6
TUBE1ENSG00000074935.9165.98340315.42870-0.926308.259907.26180HepG2CELF1
TUBE1ENSG00000074935.9250.34820339.23830-0.438403.046002.27450HepG2DAZAP1
TUBE1ENSG00000074935.9324.98300165.335500.974907.297006.24790HepG2DDX21
TUBE1ENSG00000074935.9244.93450161.673700.599202.833801.90700HepG2DDX24
TUBE1ENSG00000074935.9522.32440305.205500.775105.828904.95350HepG2DDX3X
TUBE1ENSG00000074935.9232.67580152.148700.612702.407801.37930HepG2AGO1
TUBE1ENSG00000074935.9343.57230245.637900.484002.762501.59550HepG2EIF2S2
TUBE1ENSG00000074935.9439.15730334.614800.392102.328301.54860HepG2EIF4G1
TUBE1ENSG00000074935.91171.92500579.651101.0155024.7290023.24160HepG2ETF1
TUBE1ENSG00000074935.9194.45200133.452000.543002.147001.36330HepG2GEMIN5
TUBE1ENSG00000074935.9254.11140462.87080-0.865106.350305.40670HepG2GPKOW
TUBE1ENSG00000074935.9333.20910231.591300.524702.592201.91890HepG2HNRNPC
TUBE1ENSG00000074935.9214.79110309.04290-0.524903.666202.89770HepG2HNRNPL
TUBE1ENSG00000074935.9452.05530282.713200.677104.007303.26010HepG2MATR3
TUBE1ENSG00000074935.9380.73440264.661500.524503.331102.44660HepG2MSI2
TUBE1ENSG00000074935.9405.95640289.368600.488302.334001.75010HepG2NCBP2
TUBE1ENSG00000074935.9284.33640391.67230-0.462002.204801.53500HepG2NSUN2
TUBE1ENSG00000074935.9379.74330257.682900.559302.793902.06860HepG2PABPC4
TUBE1ENSG00000074935.9517.77520310.769000.736403.972202.14340HepG2PNPT1
TUBE1ENSG00000074935.9277.24030205.192900.434102.246901.57570HepG2PPIL4
TUBE1ENSG00000074935.9363.19500216.758100.744603.739902.33240HepG2PRPF6
TUBE1ENSG00000074935.9284.29630191.941300.566602.586801.80430HepG2PRPF8
TUBE1ENSG00000074935.9182.27090321.08720-0.816905.922005.09430HepG2PUF60
TUBE1ENSG00000074935.9262.69290340.59000-0.374701.991101.41640HepG2PUM2
TUBE1ENSG00000074935.9465.89380296.781600.650505.292004.46920HepG2QKI
TUBE1ENSG00000074935.9340.59440484.47810-0.508404.012503.41860HepG2RBM22
TUBE1ENSG00000074935.9362.25260269.350200.427402.224701.61470HepG2RBM25
TUBE1ENSG00000074935.9497.53560334.684100.571902.939801.34850HepG2RBM47
TUBE1ENSG00000074935.9237.56900325.25800-0.453201.989301.39890HepG2RPLP0
TUBE1ENSG00000074935.9294.85840195.424500.593302.411001.52850HepG2RPS10
TUBE1ENSG00000074935.9543.97340269.983201.010608.131306.93050HepG2SF3A3
TUBE1ENSG00000074935.9380.82290285.301500.416502.464801.90220HepG2SF3B4
TUBE1ENSG00000074935.9349.56530194.105800.848602.959301.30410HepG2SLTM
TUBE1ENSG00000074935.9280.05000486.48670-0.796704.314703.33000HepG2SNRNP70
TUBE1ENSG00000074935.9405.04500297.794600.443702.735002.26410HepG2SRSF1
TUBE1ENSG00000074935.9315.93550470.44860-0.574402.900601.87090HepG2SRSF3
TUBE1ENSG00000074935.9289.34620185.962600.637702.494601.35550HepG2SUB1
TUBE1ENSG00000074935.9100.30020247.66650-1.304107.489006.46440HepG2SUPV3L1
TUBE1ENSG00000074935.9469.02950267.674000.809108.332907.44460HepG2TAF15
TUBE1ENSG00000074935.999.83460166.00670-0.733602.746901.75500HepG2TFIP11
TUBE1ENSG00000074935.9316.54610199.768800.664002.849401.36000HepG2TRA2A
TUBE1ENSG00000074935.9155.82990239.43520-0.619703.062202.33550HepG2UPF1
TUBE1ENSG00000074935.9484.07760231.163101.0662013.8043012.62010HepG2UTP3
TUBE1ENSG00000074935.9301.33900195.635500.623102.532601.33270HepG2XRCC5
TUBE1ENSG00000074935.9351.66630218.818900.684403.462902.27690HepG2XRCC6
TUBE1ENSG00000074935.9216.66110295.01670-0.445402.604601.94950HepG2ZC3H8
TUBE1ENSG00000074935.9557.09490263.330901.0809017.1913016.11840HepG2ZNF622
TUBE1ENSG00000074935.9529.94150805.67420-0.604404.608903.00520K562ABCF1
TUBE1ENSG00000074935.91685.939002229.77140-0.403303.973703.18900K562AKAP8L
TUBE1ENSG00000074935.9488.840801111.56960-1.1852017.9354016.60810K562AQR
TUBE1ENSG00000074935.9378.18550491.10840-0.376902.501501.59140K562BCLAF1
TUBE1ENSG00000074935.9325.76400505.40930-0.633602.698601.83610K562BOP1
TUBE1ENSG00000074935.9361.58150561.14660-0.634104.492402.62640K562BUD13
TUBE1ENSG00000074935.91963.510202560.82080-0.383204.517702.97070K562CCDC124
TUBE1ENSG00000074935.9922.739301226.64150-0.410703.486302.03650K562CIRBP
TUBE1ENSG00000074935.9430.839601128.77960-1.3895013.9728011.63270K562CNOT7
TUBE1ENSG00000074935.9574.56840928.70390-0.6927010.071107.97600K562CPEB4
TUBE1ENSG00000074935.9352.92610537.42430-0.606703.892002.96250K562CPSF6
TUBE1ENSG00000074935.9821.432401322.53600-0.6871011.030309.15510K562CELF1
TUBE1ENSG00000074935.9551.19210757.39760-0.458503.961702.68380K562DDX3X
TUBE1ENSG00000074935.9467.19310960.85470-1.0403023.3043021.60150K562DDX47
TUBE1ENSG00000074935.9139.59440309.90980-1.150602.658001.34270K562DNAJC21
TUBE1ENSG00000074935.9273.52900381.44280-0.479802.388201.54160K562EFTUD2
TUBE1ENSG00000074935.9599.02160831.91720-0.473805.522803.78170K562EIF2S1
TUBE1ENSG00000074935.9712.68820532.743400.419702.282501.62000K562EIF2S2
TUBE1ENSG00000074935.9292.59120408.44620-0.481302.220001.30340K562EIF3D
TUBE1ENSG00000074935.9229.18430757.72970-1.7252040.4272037.36570K562EIF3G
TUBE1ENSG00000074935.9408.22630791.28660-0.9548012.9562011.12420K562EIF4A3
TUBE1ENSG00000074935.9653.722101075.40470-0.7181012.0967010.20880K562EIF4G2
TUBE1ENSG00000074935.9392.32800579.08450-0.561704.319003.24430K562FIP1L1
TUBE1ENSG00000074935.9358.82150546.75990-0.607604.309503.24210K562FMR1
TUBE1ENSG00000074935.9222.61040463.40370-1.057708.893507.16640K562FTO
TUBE1ENSG00000074935.9407.76980822.90350-1.0130018.4085016.95810K562FXR1
TUBE1ENSG00000074935.91270.56720833.702600.607802.485601.82150K562G3BP2
TUBE1ENSG00000074935.9447.75930622.75620-0.475904.169802.77850K562GLRX3
TUBE1ENSG00000074935.9231.01470513.13130-1.151307.844706.50220K562GPKOW
TUBE1ENSG00000074935.9435.45580709.97930-0.705305.531804.46010K562GRSF1
TUBE1ENSG00000074935.9546.930701056.24970-0.949507.572605.08700K562HNRNPAB
TUBE1ENSG00000074935.9255.71690502.87040-0.9756010.048108.96740K562HNRNPC
TUBE1ENSG00000074935.9303.91920449.14010-0.563503.824702.45800K562HNRNPF
TUBE1ENSG00000074935.9553.66100868.38550-0.649307.316705.51890K562HNRNPL
TUBE1ENSG00000074935.91458.44200785.162900.8933013.2099011.51440K562HSPD1
TUBE1ENSG00000074935.9741.360401163.84680-0.650704.915203.23780K562IGF2BP3
TUBE1ENSG00000074935.9540.429701029.99590-0.930506.158003.98220K562ILF2
TUBE1ENSG00000074935.9670.20000448.577100.579105.101602.92810K562LSM11
TUBE1ENSG00000074935.9792.849301202.81890-0.601306.442105.13210K562MAGOH
TUBE1ENSG00000074935.9690.881901200.44880-0.7971010.116108.24690K562MATR3
TUBE1ENSG00000074935.9284.64950500.86360-0.815206.473405.10460K562METAP2
TUBE1ENSG00000074935.9607.812901146.23460-0.9152013.7662011.43420K562MSI2
TUBE1ENSG00000074935.9372.57380654.75050-0.8134011.7104010.17590K562MTPAP
TUBE1ENSG00000074935.9848.360801176.40510-0.471604.650902.68130K562NOL12
TUBE1ENSG00000074935.9466.93980727.46660-0.639609.248907.99280K562NSUN2
TUBE1ENSG00000074935.9495.133001084.42430-1.131009.265307.00340K562PABPC1
TUBE1ENSG00000074935.9654.026101070.29500-0.710608.656206.89120K562PCBP2
TUBE1ENSG00000074935.9207.37990326.82600-0.656204.260103.26230K562POLR2G
TUBE1ENSG00000074935.9496.41690657.32690-0.405102.575201.78820K562PPIG
TUBE1ENSG00000074935.9446.806601168.57960-1.3870020.6730018.93130K562PTBP1
TUBE1ENSG00000074935.9545.456101173.31550-1.1051017.7908015.66490K562PUF60
TUBE1ENSG00000074935.9799.601201222.78860-0.612809.874008.04050K562PUM2
TUBE1ENSG00000074935.91603.549002154.58850-0.426105.898005.05960K562RBM15
TUBE1ENSG00000074935.9482.689701120.77960-1.2153020.5117018.00830K562RBM22
TUBE1ENSG00000074935.9562.116601179.38250-1.0691011.836409.57360K562NELFE
TUBE1ENSG00000074935.9558.08340746.23330-0.419104.601302.55970K562RPS10
TUBE1ENSG00000074935.9215.64990378.12200-0.810204.837203.75510K562RPS19
TUBE1ENSG00000074935.9640.368101006.63500-0.652603.787601.92680K562RPS3A
TUBE1ENSG00000074935.9503.84520836.06910-0.730603.013901.96370K562RPS3
TUBE1ENSG00000074935.9252.68170379.55190-0.587002.651001.35090K562RRP9
TUBE1ENSG00000074935.9668.915001028.13390-0.620103.432601.69450K562SBDS
TUBE1ENSG00000074935.9400.63340717.85370-0.8414012.2184010.60670K562SF3A3
TUBE1ENSG00000074935.9951.03100695.803300.450703.723101.80770K562SND1
TUBE1ENSG00000074935.9449.706901145.54590-1.3490021.0581019.12520K562SRSF1
TUBE1ENSG00000074935.9608.367501006.20680-0.725903.156501.40560K562STIP1
TUBE1ENSG00000074935.9181.36000359.43640-0.986906.989805.32080K562SUPV3L1
TUBE1ENSG00000074935.9462.12680327.806300.495303.477402.55760K562SYNCRIP
TUBE1ENSG00000074935.9487.282001159.47850-1.2506015.9967014.02340K562TARDBP
TUBE1ENSG00000074935.9200.75740327.62050-0.706604.278602.20960K562TFIP11
TUBE1ENSG00000074935.9289.39350433.67530-0.583603.492202.43530K562TIAL1
TUBE1ENSG00000074935.9343.12810460.83790-0.425502.566201.66170K562TRIM56
TUBE1ENSG00000074935.9504.47130677.59590-0.425702.792201.40590K562TRIP6
TUBE1ENSG00000074935.9456.84470688.59500-0.592005.471103.67180K562TROVE2
TUBE1ENSG00000074935.91076.289601323.07780-0.297802.807101.39500K562UBE2L3
TUBE1ENSG00000074935.9223.62010380.39550-0.766505.063503.64220K562UCHL5
TUBE1ENSG00000074935.9439.31660771.34990-0.8121013.5165012.07350K562UPF1
TUBE1ENSG00000074935.9418.90470686.35900-0.7123010.490508.96730K562WDR43
TUBE1ENSG00000074935.9861.178501317.33880-0.613206.903504.86460K562WRN
TUBE1ENSG00000074935.9222.24230387.31160-0.801405.715303.75930K562XRN2
TUBE1ENSG00000074935.9770.731801252.05590-0.700006.556605.13900K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TUBE1 is not available on ENCORE database.





12 RBPs can affect the splicing of TUBE1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETUBE1ENSG00000074935.9chr6-112400835112400957112397524112397712112402294112402410-0.053000.007090.06176excludedK562AQR
SETUBE1ENSG00000074935.9chr6-1124068611124069461124053911124054491124077581124078110.155000.000170.06626includedK562KHSRP
SETUBE1ENSG00000074935.9chr6-112405391112405449112402294112402410112407758112407811-0.185000.000580.01462excludedK562U2AF1
SETUBE1ENSG00000074935.9chr6-1124053911124054491124022941124024101124077581124078110.235000.000560.05965includedHepG2LARP4
SETUBE1ENSG00000074935.9chr6-112405391112405449112402294112402410112407758112407811-0.060000.001070.06778excludedK562HNRNPUL1
SETUBE1ENSG00000074935.9chr6-1124053911124054491124022941124024101124077581124078110.157000.000890.03439includedK562HNRNPU
A3SSTUBE1ENSG00000074935.9chr6-1123971391123973741123971391123973151123975241123977120.244000.000370.07588longerHepG2PTBP1
A3SSTUBE1ENSG00000074935.9chr6-1123971391123973741123971391123973151123975241123977120.262000.000000.00000longerK562PUS1
A3SSTUBE1ENSG00000074935.9chr6-1123971391123973741123971391123973151123975241123977120.146000.000270.04650longerK562UTP18
A3SSTUBE1ENSG00000074935.9chr6-1123971391123973741123971391123973151123975241123977120.151000.000420.04828longerK562RBM15
A3SSTUBE1ENSG00000074935.9chr6-1123971391123973741123971391123973151123975241123977120.308000.000030.00458longerHepG2SF3B4
MXETUBE1ENSG00000074935.9chr6-1123959121123960531123971391123973741123939601123941011123975241123977120.052000.007370.049441includedK562AQR
MXETUBE1ENSG00000074935.9chr6-1123959121123960531123971391123973441123939601123941011123975241123977120.069000.005890.041281includedK562AQR
MXETUBE1ENSG00000074935.9chr6-112397524112397712112400835112400957112397201112397315112402294112402410-0.159000.000440.026232includedK562IGF2BP2
MXETUBE1ENSG00000074935.9chr6-1124053911124054491124084351124085091124022941124024101124086121124087120.089000.007980.083621includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TUBE1 is not avaliable on ENCORE database.