PRNP

General Information

Gene Name       : PRNP
Gene ID             : ENSG00000171867.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PRNP)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRNPENSG00000171867.165.504.715.11ENCSR000AEF
HepG2PRNPENSG00000171867.16170.17116.37143.27ENCSR985KAT
K562PRNPENSG00000171867.1618.9120.3819.64ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRNP is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRNP RNA is bound by 26 proteins.  







eCLIP assay for PRNP is not avaliable on ENCORE database.





26 proteins are bound to PRNP RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2046810834681207+3'-UTR3.550366.98582K562UPF1
chr2046809614681014+3'-UTR3.901548.99360HepG2UPF1
chr2046798614679946+3'-UTR,CDS,intron-Proximal4.4657737.13649HepG2DDX3X
chr2046820214682158+3'-UTR3.983478.99296HepG2DDX55
chr2046809854681014+3'-UTR3.882959.47941HepG2IGF2BP1
chr2046815194681559+3'-UTR3.834236.19596HepG2UPF1
chr2046807414680793+3'-UTR4.495793.89948K562YBX3
chr2046818054681858+3'-UTR3.248574.91593K562FAM120A
chr2046806624680717+3'-UTR3.288086.87544HepG2RBFOX2
chr2046811344681208+3'-UTR3.9682011.48310HepG2IGF2BP3
chr2046812234681293+3'-UTR4.777665.44143HepG2IGF2BP3
chr2046806814680708+3'-UTR4.520905.64948HepG2UPF1
chr2046807814680839+3'-UTR3.203013.87633HepG2IGF2BP1
chr2046809624680985+3'-UTR4.413059.09952HepG2IGF2BP1
chr2046812174681270+3'-UTR5.5602812.68758HepG2IGF2BP1
chr2046804704680637+3'-UTR,CDS5.089955.54797K562SND1
chr2046806644680677+3'-UTR3.334544.79152HepG2IGF2BP3
chr2046807234680776+3'-UTR3.517785.68826HepG2TROVE2
chr2046821444682218+3'-UTR4.732569.89284HepG2FUBP3
chr2046807204680777+3'-UTR3.754815.72266HepG2AKAP1
chr2046811394681207+3'-UTR3.391788.83800HepG2IGF2BP1
chr2046806634680798+3'-UTR4.126278.84200K562PABPC4
chr2046818044681880+3'-UTR3.925218.71030K562UPF1
chr2046807494680867+3'-UTR3.148577.27935HepG2YBX3
chr2046807184680746+3'-UTR3.381764.01314HepG2IGF2BP1
chr2046806624680706+3'-UTR3.086349.11150HepG2LARP4
chr2046818094681852+3'-UTR4.075867.59881HepG2UPF1
chr2046820254682063+3'-UTR4.349214.07810K562UPF1
chr2046809624681012+3'-UTR4.676535.85248HepG2IGF2BP3
chr2046807134680793+3'-UTR5.8124914.63716HepG2UPF1
chr2046810574681118+3'-UTR3.484016.70965HepG2UPF1
chr2046807534680820+3'-UTR3.550664.37861HepG2IGF2BP3
chr2046818034681884+3'-UTR3.4769710.13957HepG2FUBP3
chr2046809054680961+3'-UTR4.9834514.05615HepG2UPF1
chr2046807464680781+3'-UTR3.716795.13058HepG2IGF2BP1
chr2046806614680754+3'-UTR4.2611514.82179HepG2TIAL1
chr2046810664681107+3'-UTR4.045973.84520HepG2TIA1
chr2046806654680774+3'-UTR3.8497913.91259K562TIA1
chr2046807214680792+3'-UTR3.0370510.84579HepG2LARP4
chr2046811284681197+3'-UTR4.3047815.47067HepG2UPF1
chr2046808124680853+3'-UTR4.279123.34655HepG2AKAP1
chr2046806624680730+3'-UTR3.8362218.35988HepG2TIA1
chr2046820054682081+3'-UTR6.163827.33718HepG2DDX6
chr2046819924682081+3'-UTR3.149488.88589HepG2FUBP3
chr2046806774680723+3'-UTR3.371086.76859HepG2IGF2BP3
chr2046808134680843+3'-UTR4.943366.52213HepG2UPF1
chr2046821124682159+3'-UTR4.691763.14375HepG2RBFOX2
chr2046810754681115+3'-UTR3.602933.14501HepG2IGF2BP3
chr2046671824667264+5'-UTR,intron-Distal,intron-Proximal4.495406.80961HepG2EFTUD2
chr2046670994667159+5'-UTR,intron-Proximal4.7212813.13184HepG2DDX3X
chr2046802044680264+CDS3.214775.59842HepG2GRSF1
chr2046801184680171+CDS4.7224142.70410HepG2SND1
chr2046801874680283+CDS3.151313.14823K562SND1
chr2046802834680366+CDS4.639954.57227K562SND1
chr2046805314680587+CDS4.2690524.52616HepG2SND1
chr2046804734680531+CDS3.3923814.80388HepG2SND1
chr2046799584680020+CDS5.0444926.26790HepG2RPS3
chr2046801954680272+CDS5.8369313.35798HepG2RPS3
chr2046804154680520+CDS3.300847.74484HepG2LIN28B
chr2046800514680171+CDS5.0605333.59660HepG2RPS3
chr2046800714680118+CDS5.1506629.97062HepG2SND1
chr2046799464680024+CDS3.0672911.48245HepG2DDX3X
chr2046800704680149+CDS5.684146.19827HepG2DDX6
chr2046801974680302+CDS5.3165250.16608HepG2SND1
chr2046799484680031+CDS3.9435712.05467HepG2GRSF1
chr2046800314680149+CDS4.5102221.62479HepG2GRSF1
chr2046679114667991+intron-Distal3.804643.71694HepG2NKRF
chr2046770884677144+intron-Distal3.728783.16028HepG2SUGP2
chr2046674084667472+intron-Distal,intron-Proximal4.234833.63902HepG2CSTF2T
chr2046778754677986+intron-Distal3.823893.91876HepG2U2AF2
chr2046765204676583+intron-Distal4.151734.53347HepG2SUGP2
chr2046675694667632+intron-Distal3.666813.05559HepG2DGCR8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRNP is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRNP is not available on ENCORE database.

  • 113 RBPs can affect the levels of PRNP.  








The Knockdown/knockout RNA-Seq assay for PRNP is not available on ENCORE database.





113 RBPs can affect the gene expression of PRNP :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRNPENSG00000171867.123168.233604265.33860-0.429003.906202.80030HepG2ABCF1
PRNPENSG00000171867.127232.861304742.076300.608906.558505.77850HepG2AKAP1
PRNPENSG00000171867.124825.424403827.493800.334202.494301.50300HepG2AKAP8
PRNPENSG00000171867.124986.169303923.680600.345602.868502.06960HepG2ASCC1
PRNPENSG00000171867.125616.231104990.489400.170302.128201.51220HepG2AUH
PRNPENSG00000171867.128600.690305219.018400.7206014.0965012.89330HepG2BOP1
PRNPENSG00000171867.126094.958203976.542500.6160011.389909.99620HepG2CALR
PRNPENSG00000171867.123970.844603020.859300.394401.973001.33220HepG2CNOT7
PRNPENSG00000171867.124875.501803512.934900.472807.087605.39290HepG2CPSF7
PRNPENSG00000171867.129268.043104272.717801.1170059.8031057.61340HepG2CELF1
PRNPENSG00000171867.121351.820002613.03760-0.9508019.8860018.27070HepG2DDX21
PRNPENSG00000171867.125213.268503902.110700.417803.359602.68620HepG2DDX6
PRNPENSG00000171867.122086.400403102.37880-0.572408.256006.65770HepG2DHX30
PRNPENSG00000171867.122576.449602915.02720-0.178101.911101.33220HepG2DKC1
PRNPENSG00000171867.122702.250403188.04470-0.238504.168003.39890HepG2DNAJC2
PRNPENSG00000171867.121658.263502406.42000-0.537204.212702.83180HepG2AGO1
PRNPENSG00000171867.122803.214903751.24690-0.420303.769403.08440HepG2EIF2S1
PRNPENSG00000171867.123324.534002490.727500.416504.079402.99560HepG2EIF3D
PRNPENSG00000171867.121819.328602467.74640-0.439805.742504.26790HepG2EIF3G
PRNPENSG00000171867.126921.786304036.268900.778008.111006.96430HepG2EIF4B
PRNPENSG00000171867.123975.637904532.51970-0.189102.640901.81970HepG2EIF4G1
PRNPENSG00000171867.122961.040104341.91200-0.552207.541906.22430HepG2EIF4G2
PRNPENSG00000171867.1210609.366105729.642500.8887046.8972044.99090HepG2ETF1
PRNPENSG00000171867.129045.204704307.035701.0704020.1371018.40140HepG2FIP1L1
PRNPENSG00000171867.124537.142803434.461300.401602.380501.33950HepG2FUS
PRNPENSG00000171867.123023.698604182.65320-0.468104.723903.83600HepG2FXR1
PRNPENSG00000171867.122598.446103880.06510-0.578406.095805.12530HepG2G3BP1
PRNPENSG00000171867.123615.034205431.75450-0.587406.513305.55920HepG2GPKOW
PRNPENSG00000171867.124041.059102796.151500.531203.665402.38170HepG2GRSF1
PRNPENSG00000171867.124020.068202908.835700.4667011.361109.57750HepG2HDGF
PRNPENSG00000171867.123449.234802552.923000.434002.727201.37150HepG2HNRNPA0
PRNPENSG00000171867.121595.240203247.42230-1.0255024.9140023.32200HepG2HNRNPA1
PRNPENSG00000171867.125147.205004222.356400.285604.668603.50670HepG2HNRNPA2B1
PRNPENSG00000171867.123498.509804818.20270-0.4618010.734009.44220HepG2HNRNPF
PRNPENSG00000171867.122835.126405183.59820-0.8705012.7686011.54660HepG2HNRNPLL
PRNPENSG00000171867.123719.121002971.856800.323503.666402.58350HepG2HNRNPM
PRNPENSG00000171867.123062.919203588.22670-0.228403.190902.54340HepG2HNRNPU
PRNPENSG00000171867.122881.555304744.59240-0.7194016.4348014.83470HepG2IGF2BP1
PRNPENSG00000171867.123210.355103665.26390-0.191203.047402.28100HepG2ILF2
PRNPENSG00000171867.123566.042902908.628400.293902.414301.35890HepG2LARP7
PRNPENSG00000171867.122772.856704184.11310-0.593506.843305.82560HepG2MAGOH
PRNPENSG00000171867.126263.230204207.543800.573806.080205.17230HepG2MATR3
PRNPENSG00000171867.123661.610302606.838200.490103.026401.92550HepG2METAP2
PRNPENSG00000171867.123975.138705285.98780-0.411202.501501.58380HepG2MTPAP
PRNPENSG00000171867.122602.559404306.66530-0.726609.427908.30010HepG2NCBP2
PRNPENSG00000171867.122027.816202629.92090-0.375103.730002.06730HepG2NIP7
PRNPENSG00000171867.123012.738004596.04900-0.609308.629807.36130HepG2NSUN2
PRNPENSG00000171867.124843.697102760.587500.811006.047804.69900HepG2PABPC1
PRNPENSG00000171867.125361.767403551.796400.5941018.6789016.84740HepG2PARN
PRNPENSG00000171867.124634.631203877.382400.257304.053503.34580HepG2PCBP1
PRNPENSG00000171867.121943.768902790.31180-0.521604.290402.20950HepG2PHF6
PRNPENSG00000171867.122546.381803200.42080-0.329804.720303.78450HepG2PPIL4
PRNPENSG00000171867.123094.796203578.23890-0.209402.586401.83690HepG2PRPF4
PRNPENSG00000171867.123194.367303945.32280-0.304604.919804.23370HepG2PTBP1
PRNPENSG00000171867.125322.908004616.480000.205303.863603.18810HepG2PUM1
PRNPENSG00000171867.126546.664404613.171000.504909.513608.30840HepG2PUM2
PRNPENSG00000171867.122281.914603103.45190-0.4436010.750809.67240HepG2PUS1
PRNPENSG00000171867.122629.590404273.00730-0.7004018.1447016.74090HepG2QKI
PRNPENSG00000171867.128257.692403137.435901.3961016.6314015.04670HepG2RAVER1
PRNPENSG00000171867.125307.377204389.849500.273703.081002.18010HepG2RBM15
PRNPENSG00000171867.127004.317704788.943200.5484014.5910013.59110HepG2RBM22
PRNPENSG00000171867.122853.492703877.98140-0.442606.195805.22370HepG2RBM25
PRNPENSG00000171867.121891.805802848.15540-0.590306.443804.82320HepG2RCC2
PRNPENSG00000171867.122926.849104390.81430-0.5851012.7413011.73720HepG2NELFE
PRNPENSG00000171867.122948.098004089.35830-0.4721012.0258010.87780HepG2RECQL
PRNPENSG00000171867.123298.100005189.81300-0.6540010.938709.73590HepG2RPLP0
PRNPENSG00000171867.123276.405802423.504500.434905.769104.91910HepG2RPS19
PRNPENSG00000171867.124046.392302309.226800.8091011.214909.80060HepG2RRP9
PRNPENSG00000171867.122435.438503195.50580-0.391909.087208.02610HepG2SAFB2
PRNPENSG00000171867.125099.445203659.734000.478503.677702.89710HepG2SF3A3
PRNPENSG00000171867.123762.230404169.73780-0.148402.156501.52370HepG2SLBP
PRNPENSG00000171867.124322.787603199.269000.434102.829601.86200HepG2SMNDC1
PRNPENSG00000171867.128256.666605708.967200.532202.147401.46230HepG2SNRNP70
PRNPENSG00000171867.127090.591905408.974600.3905011.4885010.65650HepG2SRFBP1
PRNPENSG00000171867.123349.629904287.50200-0.356107.925807.22180HepG2SRSF1
PRNPENSG00000171867.127525.502005520.408000.446902.547501.59070HepG2SRSF3
PRNPENSG00000171867.126033.499504293.813500.4906013.6370012.39150HepG2SRSF5
PRNPENSG00000171867.123975.862704733.59290-0.251703.536802.76340HepG2SRSF7
PRNPENSG00000171867.125464.480903488.074200.6476016.8991015.74160HepG2SRSF9
PRNPENSG00000171867.122832.564804696.33960-0.7294028.9209027.66000HepG2SSB
PRNPENSG00000171867.126395.326204152.144700.623106.973305.07680HepG2SSRP1
PRNPENSG00000171867.124760.818002932.022800.699206.031504.27630HepG2SUB1
PRNPENSG00000171867.122494.880504883.35300-0.9689058.7249056.56250HepG2SUCLG1
PRNPENSG00000171867.122957.396002019.035400.550605.570504.22640HepG2TFIP11
PRNPENSG00000171867.122201.257303486.83150-0.6636014.4367013.45230HepG2TIAL1
PRNPENSG00000171867.124870.897703517.787900.4694012.4090011.33960HepG2TRIM56
PRNPENSG00000171867.125819.691403684.558400.6594010.300209.07050HepG2U2AF1
PRNPENSG00000171867.125747.670904496.919600.353902.754401.91970HepG2UBE2L3
PRNPENSG00000171867.121293.092302758.44880-1.0930012.8753010.63220HepG2UPF2
PRNPENSG00000171867.122737.192303336.06090-0.285404.196402.93950HepG2UTP18
PRNPENSG00000171867.123647.183803133.524000.218903.216302.57910HepG2UTP3
PRNPENSG00000171867.121610.501102965.21750-0.8806013.7802012.17500HepG2XRN2
PRNPENSG00000171867.122835.663303531.22200-0.316506.738805.76560HepG2ZC3H8
PRNPENSG00000171867.127887.352003569.566301.14370105.75370103.71240HepG2ZNF622
PRNPENSG00000171867.12777.043301234.19710-0.6675012.0980011.00460K562AGGF1
PRNPENSG00000171867.121028.582201347.44360-0.389604.531803.33160K562ATP5C1
PRNPENSG00000171867.121117.62100651.941500.7775010.104307.87800K562CIRBP
PRNPENSG00000171867.121517.834201088.930300.479002.264501.32230K562CNOT7
PRNPENSG00000171867.122429.914101665.028100.5453010.016508.22010K562CELF1
PRNPENSG00000171867.12405.55910539.60090-0.412003.286101.82800K562DDX27
PRNPENSG00000171867.121017.908201187.38300-0.222201.942701.37860K562DDX47
PRNPENSG00000171867.121240.09040897.476000.466404.023802.98870K562FMR1
PRNPENSG00000171867.12789.31150525.841700.585906.955506.05710K562FXR1
PRNPENSG00000171867.12803.05300512.357600.648204.606203.64160K562G3BP2
PRNPENSG00000171867.12833.85660607.477900.456903.173601.84220K562HNRNPK
PRNPENSG00000171867.121155.84380795.821400.538304.271003.09820K562HNRNPM
PRNPENSG00000171867.12449.63710753.26740-0.7444010.064408.38140K562HNRNPU
PRNPENSG00000171867.121687.769001311.954800.363302.838502.03270K562HSPD1
PRNPENSG00000171867.121067.945401362.92340-0.351902.809301.97670K562KIF1C
PRNPENSG00000171867.12782.65070555.823100.493604.175202.41420K562LARP7
PRNPENSG00000171867.121147.824101526.81330-0.411604.172803.02010K562MBNL1
PRNPENSG00000171867.121932.997701481.458700.383704.071702.24380K562NOL12
PRNPENSG00000171867.12756.80240523.204900.532404.111402.46020K562NONO
PRNPENSG00000171867.12689.36650517.098000.414702.773302.02370K562PRPF8
PRNPENSG00000171867.122015.905001477.973300.447705.073203.97050K562PUF60
PRNPENSG00000171867.12939.148701240.94350-0.402004.407003.67660K562RBM15
PRNPENSG00000171867.121135.71280847.426700.422305.003903.93430K562SF3A3
PRNPENSG00000171867.121146.34650800.917500.517202.279901.40660K562SF3B1
PRNPENSG00000171867.12675.35130533.218800.340802.179601.42110K562SF3B4
PRNPENSG00000171867.12657.750201289.57860-0.971308.587106.14890K562SUCLG1
PRNPENSG00000171867.12653.21520456.448100.517003.620101.69240K562TFIP11
PRNPENSG00000171867.12828.47900497.154900.736706.764404.90730K562U2AF1
PRNPENSG00000171867.12662.59790513.284700.368302.802801.99400K562U2AF2
PRNPENSG00000171867.121226.13610910.632500.429105.863704.86180K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRNP is not available on ENCORE database.






No RBPs affect the alternative splcing events of PRNP on ENCORE database.





The Knockdown/knockout RNA-Seq assay for PRNP is not avaliable on ENCORE database.