MCM10

General Information

Gene Name       : MCM10
Gene ID             : ENSG00000065328.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MCM10)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MCM10ENSG00000065328.1613.5716.4114.99ENCSR000AEF
HepG2MCM10ENSG00000065328.1615.1822.8719.02ENCSR985KAT
K562MCM10ENSG00000065328.1628.9232.3030.61ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
MCM10Ribo-STAMP-293TshRNAMCM10-BGRSLV07-15,MCM10-BGRSLV07-16NT-BGRSLV07-1,NT-BGRSLV07-2,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MCM10 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MCM10 RNA is bound by 11 proteins.  







eCLIP assay for MCM10 is not avaliable on ENCORE database.





11 proteins are bound to MCM10 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr101325259713252658+3'-UTR4.530924.46422K562UPF1
chr101325236613252423+3'-UTR3.491284.14747K562FAM120A
chr101321292013212950+3'-UTR,CDS,intron-Proximal3.204154.74755K562ZNF622
chr101325252613252597+3'-UTR4.224435.24353K562UPF1
chr101325295513253064+3'-UTR7.9700320.44795K562PUM2
chr101325246413252525+3'-UTR4.703085.38606K562FAM120A
chr101320613913206210+5'-UTR,CDS,intron-Distal,intron-Proximal3.812777.95479K562ZNF622
chr101324623513246305+CDS3.476063.69481K562UCHL5
chr101321316013213261+CDS4.590124.97342HepG2PPIG
chr101323327113233318+CDS,intron-Proximal4.747594.13847K562AQR
chr101322817313228278+CDS4.348783.56019HepG2GRWD1
chr101323084813230921+CDS,intron-Proximal4.483394.49756K562BUD13
chr101322820213228278+CDS3.366366.02234K562UCHL5
chr101324342013243497+CDS,intron-Proximal3.154904.00731K562UCHL5
chr101321319813213255+CDS3.347635.65349K562UCHL5
chr101324350213243530+CDS3.255563.36945K562ZNF622
chr101322251013222604+CDS4.161097.87612K562UCHL5
chr101322818113228256+CDS4.463873.91454K562PUM1
chr101321482913214899+intron-Distal,intron-Proximal4.824935.70555K562PRPF8
chr101324637913246457+intron-Proximal3.700563.20886K562PRPF8
chr101323108013231133+intron-Proximal4.527314.13847K562AQR
chr101323108713231162+intron-Proximal3.238343.18246K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MCM10 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MCM10 is not available on ENCORE database.

  • 138 RBPs can affect the levels of MCM10.  








The Knockdown/knockout RNA-Seq assay for MCM10 is not available on ENCORE database.





138 RBPs can affect the gene expression of MCM10 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MCM10ENSG00000065328.12313.69810429.43530-0.453103.492002.82260HepG2ACO1
MCM10ENSG00000065328.12135.58420307.63520-1.182007.601106.76500HepG2AKAP1
MCM10ENSG00000065328.1231.18870117.21010-1.910003.898202.66530HepG2AKAP8
MCM10ENSG00000065328.12303.82880431.51260-0.506104.002703.09250HepG2AKAP8L
MCM10ENSG00000065328.1257.44630254.54620-2.1476018.9588017.12760HepG2ASCC1
MCM10ENSG00000065328.12291.79510762.92450-1.3866031.1204029.25980HepG2AUH
MCM10ENSG00000065328.12365.72210569.27610-0.638404.510903.31380HepG2BCCIP
MCM10ENSG00000065328.12200.27860494.59330-1.3042014.0034012.21060HepG2BCLAF1
MCM10ENSG00000065328.1229.56380666.12670-4.49390102.47480100.09810HepG2BOP1
MCM10ENSG00000065328.12177.94520511.93610-1.5245022.1182020.33030HepG2CALR
MCM10ENSG00000065328.12443.32140633.46710-0.514902.803301.82090HepG2CCAR1
MCM10ENSG00000065328.12154.74300241.83520-0.644202.807802.02970HepG2CIRBP
MCM10ENSG00000065328.12174.78620429.41380-1.2968019.3328017.92650HepG2CKAP4
MCM10ENSG00000065328.12225.23730611.53980-1.4410018.9465017.34330HepG2CPSF6
MCM10ENSG00000065328.12471.62390611.19350-0.374003.019602.35320HepG2CELF1
MCM10ENSG00000065328.12483.08980657.24540-0.444104.988404.03510HepG2DAZAP1
MCM10ENSG00000065328.12303.74170397.19920-0.387002.468301.67640HepG2DDX19B
MCM10ENSG00000065328.12185.05280421.10920-1.1863011.140609.88640HepG2DDX21
MCM10ENSG00000065328.12288.55330411.81880-0.513203.327102.32120HepG2DDX24
MCM10ENSG00000065328.1225.10480294.69970-3.5532041.3274039.19250HepG2DDX3X
MCM10ENSG00000065328.1239.4283079.90980-1.019102.845601.53630HepG2DDX47
MCM10ENSG00000065328.12221.26390559.74960-1.3390014.7851013.18500HepG2DDX55
MCM10ENSG00000065328.12291.76800694.44860-1.251009.427407.69550HepG2DDX59
MCM10ENSG00000065328.1243.37000253.13340-2.5451022.0630020.54310HepG2DDX6
MCM10ENSG00000065328.12169.51040309.82350-0.870106.056404.64340HepG2DHX30
MCM10ENSG00000065328.12319.97750410.87180-0.360702.140201.53240HepG2DKC1
MCM10ENSG00000065328.12180.53740321.21100-0.831205.728604.74820HepG2DNAJC21
MCM10ENSG00000065328.12183.75880318.44150-0.793205.179204.33150HepG2DNAJC2
MCM10ENSG00000065328.12213.36520319.55350-0.582703.110001.93750HepG2EFTUD2
MCM10ENSG00000065328.12174.65010387.55290-1.149909.143307.22060HepG2AGO1
MCM10ENSG00000065328.1216.38030243.36280-3.8931037.6241035.60710HepG2EIF2S1
MCM10ENSG00000065328.12147.61000311.18030-1.076007.260305.85850HepG2EIF3D
MCM10ENSG00000065328.12192.52930268.95400-0.482301.918101.38160HepG2EIF4A3
MCM10ENSG00000065328.12462.67700648.35920-0.486804.930303.86440HepG2EIF4G1
MCM10ENSG00000065328.12345.26600621.09630-0.847108.666307.25590HepG2EIF4G2
MCM10ENSG00000065328.12303.27720875.95440-1.5302039.0034037.23700HepG2ETF1
MCM10ENSG00000065328.12272.97520401.16090-0.555403.701602.40740HepG2FASTKD2
MCM10ENSG00000065328.12139.70730612.58960-2.1325015.1941012.92850HepG2FTO
MCM10ENSG00000065328.12443.61870271.334700.709103.466902.69780HepG2FXR1
MCM10ENSG00000065328.12177.02120251.71780-0.507902.034501.46090HepG2G3BP1
MCM10ENSG00000065328.12284.75570415.28030-0.544403.199302.10080HepG2GNB2L1
MCM10ENSG00000065328.12164.15900693.22590-2.0782033.0339031.10810HepG2GPKOW
MCM10ENSG00000065328.12160.57640324.28910-1.014007.115606.15260HepG2HNRNPA1
MCM10ENSG00000065328.12338.81430603.99730-0.8340011.134909.49290HepG2HNRNPA2B1
MCM10ENSG00000065328.12308.68350626.10690-1.0203016.1597014.61610HepG2HNRNPF
MCM10ENSG00000065328.12426.04870598.71920-0.490905.139104.24350HepG2HNRNPL
MCM10ENSG00000065328.12124.32610661.55840-2.4117043.3528041.33990HepG2HNRNPLL
MCM10ENSG00000065328.12328.94230616.53950-0.9064011.135909.77640HepG2IGF2BP1
MCM10ENSG00000065328.1247.59110255.87100-2.4267022.7281021.01790HepG2IGF2BP2
MCM10ENSG00000065328.12127.1468052.074401.287705.486203.72770HepG2KHDRBS1
MCM10ENSG00000065328.12337.74780668.70800-0.985408.620907.14410HepG2LARP4
MCM10ENSG00000065328.12518.66480271.429300.934105.048604.17150HepG2MAGOH
MCM10ENSG00000065328.12486.07320272.953100.832405.891504.99670HepG2MATR3
MCM10ENSG00000065328.12205.49830325.66560-0.664302.526301.51870HepG2METAP2
MCM10ENSG00000065328.12296.08150674.70830-1.188309.579607.74040HepG2MTPAP
MCM10ENSG00000065328.12309.34010586.59960-0.923208.844207.56280HepG2NSUN2
MCM10ENSG00000065328.1285.02260248.82930-1.5492011.8425010.37620HepG2PABPC4
MCM10ENSG00000065328.12333.79070252.065100.405002.213801.65990HepG2PCBP1
MCM10ENSG00000065328.12161.02170506.48780-1.6533017.0687014.83210HepG2PCBP2
MCM10ENSG00000065328.12213.25250319.61320-0.583802.520401.81370HepG2PPIL4
MCM10ENSG00000065328.12124.44220431.62520-1.7943021.7263019.78730HepG2PRPF8
MCM10ENSG00000065328.12350.22470622.10630-0.828909.050408.05600HepG2PUF60
MCM10ENSG00000065328.12556.90010660.37300-0.245901.970201.45240HepG2PUM1
MCM10ENSG00000065328.12396.38320659.90330-0.735408.372907.23440HepG2PUM2
MCM10ENSG00000065328.12194.14930277.79290-0.516802.658702.04430HepG2QKI
MCM10ENSG00000065328.12336.53210488.81640-0.538502.066401.44970HepG2RAVER1
MCM10ENSG00000065328.12309.60950562.97630-0.8626010.304208.80180HepG2RBM15
MCM10ENSG00000065328.12139.75630732.13270-2.3892062.7342060.91060HepG2RBM22
MCM10ENSG00000065328.12169.01780252.10520-0.576902.880402.19510HepG2RBM25
MCM10ENSG00000065328.12223.35020480.38840-1.104903.323501.52720HepG2RBM39
MCM10ENSG00000065328.12142.1326052.793401.428706.478304.18810HepG2RBM47
MCM10ENSG00000065328.12454.92120285.440500.672305.653104.92320HepG2NELFE
MCM10ENSG00000065328.12395.23870265.831000.572104.073903.34410HepG2RECQL
MCM10ENSG00000065328.1256.78740674.42670-3.5700083.3642080.96910HepG2RPLP0
MCM10ENSG00000065328.12129.55840480.08640-1.8897019.7692017.50460HepG2RPS10
MCM10ENSG00000065328.1285.11220302.81090-1.8310019.9774018.55760HepG2RPS19
MCM10ENSG00000065328.12253.77500452.51370-0.834406.875305.65050HepG2RPS2
MCM10ENSG00000065328.1278.17330426.94940-2.4493032.0320029.93550HepG2RRP9
MCM10ENSG00000065328.12225.71770319.11100-0.499502.688702.05100HepG2SAFB2
MCM10ENSG00000065328.12397.37770656.11680-0.723405.205304.26230HepG2SF3A3
MCM10ENSG00000065328.12200.53060654.81090-1.7073027.4202025.46220HepG2SF3B1
MCM10ENSG00000065328.12242.42930476.84670-0.976004.226402.26340HepG2SLTM
MCM10ENSG00000065328.12259.54060498.17170-0.940707.178505.58390HepG2SMNDC1
MCM10ENSG00000065328.12310.76490475.47630-0.613603.480101.67470HepG2SND1
MCM10ENSG00000065328.12190.23310728.59240-1.9373022.4656020.31210HepG2SNRNP70
MCM10ENSG00000065328.12127.52670826.91140-2.6969090.7734088.94120HepG2SRFBP1
MCM10ENSG00000065328.12753.52350278.727001.4347029.8930028.70450HepG2SRSF1
MCM10ENSG00000065328.12455.10150704.58230-0.630603.932102.71660HepG2SRSF3
MCM10ENSG00000065328.12441.30930614.21510-0.477004.683703.90570HepG2SRSF5
MCM10ENSG00000065328.12224.13860615.11920-1.4565028.7755026.99700HepG2SRSF7
MCM10ENSG00000065328.1293.84050226.75170-1.2728010.791109.82560HepG2SRSF9
MCM10ENSG00000065328.12404.22800717.94530-0.8287013.3819012.42300HepG2SSB
MCM10ENSG00000065328.12162.64600307.49710-0.918805.999504.25990HepG2STAU1
MCM10ENSG00000065328.12222.59850456.79870-1.037106.441104.64170HepG2SUB1
MCM10ENSG00000065328.12215.64460310.86830-0.527602.679601.75150HepG2SUPT6H
MCM10ENSG00000065328.1263.03290557.17090-3.1439055.7148053.48490HepG2SUPV3L1
MCM10ENSG00000065328.12156.94030644.82030-2.0387035.6841033.64750HepG2TARDBP
MCM10ENSG00000065328.12149.42900373.42100-1.3213011.679709.91830HepG2TFIP11
MCM10ENSG00000065328.1289.50690348.11800-1.9595017.7535016.68870HepG2TIAL1
MCM10ENSG00000065328.12186.66410351.31940-0.912306.132505.35120HepG2TRIM56
MCM10ENSG00000065328.12216.60010393.85140-0.862606.048905.13680HepG2U2AF1
MCM10ENSG00000065328.12136.08620549.59870-2.013908.885507.01410HepG2U2AF2
MCM10ENSG00000065328.12245.14430329.10310-0.424902.151201.48170HepG2UCHL5
MCM10ENSG00000065328.12208.27250581.87630-1.4822029.1432027.37480HepG2UPF1
MCM10ENSG00000065328.12324.68610510.06320-0.651603.986102.77200HepG2UPF2
MCM10ENSG00000065328.12401.70120598.08000-0.574205.776804.31320HepG2UTP18
MCM10ENSG00000065328.1260.10260639.95110-3.41250109.46180107.39000HepG2ZNF622
MCM10ENSG00000065328.121620.847901141.285200.506005.715803.94810K562AARS
MCM10ENSG00000065328.121609.481002009.77670-0.320402.939501.91720K562AKAP8
MCM10ENSG00000065328.121359.596401903.27380-0.485305.488604.55160K562AKAP8L
MCM10ENSG00000065328.121245.654202390.23590-0.9402017.3683016.06090K562AQR
MCM10ENSG00000065328.121427.276301996.90400-0.484506.035404.62230K562ATP5C1
MCM10ENSG00000065328.121186.175101494.46370-0.333302.364001.47900K562BCLAF1
MCM10ENSG00000065328.12869.000001322.64200-0.606006.275304.95030K562BOP1
MCM10ENSG00000065328.12573.90810761.40930-0.407902.675001.64410K562CCAR1
MCM10ENSG00000065328.121883.132402574.28520-0.451003.721502.00180K562CKAP4
MCM10ENSG00000065328.121696.839102670.30740-0.654203.083301.95340K562CNOT7
MCM10ENSG00000065328.12882.699101133.77400-0.361102.417901.43920K562CSTF2
MCM10ENSG00000065328.121466.886601847.41530-0.332804.579102.99940K562DDX21
MCM10ENSG00000065328.12550.777101028.49110-0.9010014.2366011.74850K562DDX3X
MCM10ENSG00000065328.122043.712502566.93130-0.328903.713302.97340K562DDX47
MCM10ENSG00000065328.12801.777301042.76830-0.379103.782802.18780K562DDX6
MCM10ENSG00000065328.121512.063902048.35220-0.437906.053404.68100K562DKC1
MCM10ENSG00000065328.121026.385001352.00960-0.397503.009602.05740K562EFTUD2
MCM10ENSG00000065328.12921.106601129.77070-0.294602.898101.65610K562EIF2S1
MCM10ENSG00000065328.121362.897602087.77420-0.6153012.8555011.47920K562EIF2S2
MCM10ENSG00000065328.122368.361803060.44240-0.369905.382204.09320K562EIF4G2
MCM10ENSG00000065328.12958.460501430.88250-0.578105.794604.54700K562FMR1
MCM10ENSG00000065328.12662.711301212.76240-0.8718011.045309.09410K562FTO
MCM10ENSG00000065328.121809.295101117.482900.6951015.1987013.89140K562FXR1
MCM10ENSG00000065328.12616.069801342.79880-1.1241017.6037015.53750K562GPKOW
MCM10ENSG00000065328.121598.438602782.23580-0.7996015.9176014.06970K562GRSF1
MCM10ENSG00000065328.12928.483401249.00430-0.427804.001703.29980K562HNRNPC
MCM10ENSG00000065328.121679.639802569.36570-0.613308.295306.93080K562HSPD1
MCM10ENSG00000065328.121038.599901431.63540-0.463004.672003.03940K562IGF2BP3
MCM10ENSG00000065328.121616.254302020.01310-0.321703.467502.53230K562KIF1C
MCM10ENSG00000065328.12521.979601146.48400-1.1352012.9296010.78160K562KRR1
MCM10ENSG00000065328.121575.454001933.51660-0.295502.847301.75320K562MAK16
MCM10ENSG00000065328.12899.983201310.70550-0.542406.114704.78770K562METAP2
MCM10ENSG00000065328.122540.885503262.20880-0.360503.033301.84970K562MSI2
MCM10ENSG00000065328.121613.784901908.48100-0.242002.872602.04830K562MTPAP
MCM10ENSG00000065328.121175.988401586.11600-0.431602.184101.42100K562NAA15
MCM10ENSG00000065328.12838.775101072.96360-0.355203.028001.74370K562NCBP2
MCM10ENSG00000065328.121574.506902120.49390-0.4295010.514309.18810K562NSUN2
MCM10ENSG00000065328.121682.802202565.37280-0.608302.688701.47240K562PABPC1
MCM10ENSG00000065328.12948.239101831.37450-0.949603.363302.24020K562PABPN1
MCM10ENSG00000065328.121626.298302151.37700-0.403703.848502.85730K562PPIG
MCM10ENSG00000065328.12835.381501119.83760-0.422803.472302.44420K562PSIP1
MCM10ENSG00000065328.122223.884701437.346100.6296010.518109.28100K562PTBP1
MCM10ENSG00000065328.122722.728203480.08490-0.354104.991803.68880K562PUM2
MCM10ENSG00000065328.121393.595801887.86000-0.437904.151803.50640K562PUS1
MCM10ENSG00000065328.121431.930101839.15780-0.361103.873903.18890K562RBM15
MCM10ENSG00000065328.12990.651601340.25730-0.436102.945302.10160K562RPS19
MCM10ENSG00000065328.12825.044701675.47800-1.022003.453002.07040K562SF1
MCM10ENSG00000065328.121701.726002092.38610-0.298203.708202.77120K562SF3A3
MCM10ENSG00000065328.12794.547101276.91220-0.684506.606005.06710K562SF3B1
MCM10ENSG00000065328.12894.961401154.78000-0.367703.524402.55570K562SF3B4
MCM10ENSG00000065328.121680.462301409.040200.254002.060601.44020K562SRSF1
MCM10ENSG00000065328.121022.128401330.63790-0.380503.132202.00400K562SRSF5
MCM10ENSG00000065328.12918.714801274.04160-0.471703.429702.28670K562SUPV3L1
MCM10ENSG00000065328.121994.823401588.433100.328603.508302.58420K562SYNCRIP
MCM10ENSG00000065328.121123.293301375.63500-0.292402.360301.61130K562TIA1
MCM10ENSG00000065328.12744.184401077.11140-0.533404.395003.19540K562TIAL1
MCM10ENSG00000065328.12830.910601144.15380-0.461504.215702.99440K562TRIM56
MCM10ENSG00000065328.12878.030701348.31550-0.618806.266904.66550K562UCHL5
MCM10ENSG00000065328.121319.000302248.40460-0.7695012.1645010.79140K562UPF1
MCM10ENSG00000065328.121608.499602065.49790-0.360802.845401.62650K562UTP3
MCM10ENSG00000065328.121263.767501923.88880-0.606309.103207.47640K562WDR3
MCM10ENSG00000065328.121070.829801372.80320-0.358402.458001.34020K562XRN2
MCM10ENSG00000065328.121915.600302692.89980-0.491405.803804.48050K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MCM10 is not available on ENCORE database.





8 RBPs can affect the splicing of MCM10 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMCM10ENSG00000065328.12chr10+132510901325113313246218132463641325122613253104-0.131000.000020.00088excludedK562SF3B4
SEMCM10ENSG00000065328.12chr10+132281631322828013224932132251001323088013231080-0.072000.000550.00740excludedK562AQR
SEMCM10ENSG00000065328.12chr10+132061271320620913203553132036061321292113213263-0.301000.000000.00000excludedK562U2AF1
SEMCM10ENSG00000065328.12chr10+132061271320620913203553132036061321292113213263-0.104000.002980.07617excludedK562UTP18
SEMCM10ENSG00000065328.12chr10+132061271320620913203553132036061321292113213263-0.183000.000000.00017excludedK562U2AF2
SEMCM10ENSG00000065328.12chr10+132061271320620913203553132036061321292113213263-0.100000.000170.00696excludedK562AGGF1
A3SSMCM10ENSG00000065328.12chr10+132510901325310413251226132531041324621813246364-0.371000.000010.00109shorterK562SF3B4
A3SSMCM10ENSG00000065328.12chr10+1322811613228280132281631322828013224932132251000.054000.000040.00034longerK562AQR
A3SSMCM10ENSG00000065328.12chr10+1323958913239767132396221323976713237085132372690.051000.000360.00279longerK562AQR
A3SSMCM10ENSG00000065328.12chr10+1324617713246364132462181324636413243420132435340.077000.000140.00114longerK562AQR
A3SSMCM10ENSG00000065328.12chr10+132510901325310413251226132531041324621813246364-0.064000.017790.08628shorterK562AQR
RIMCM10ENSG00000065328.12chr10+1325109013253104132510901325113313251226132531040.051000.000160.02109includedK562MTPAP
RIMCM10ENSG00000065328.12chr10+1325109013253104132510901325113313251226132531040.058000.015960.08082includedK562AQR
MXEMCM10ENSG00000065328.12chr10+13246218132463641325109013251133132434201324353413251226132517360.094000.002260.051721includedK562PPIL4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MCM10 is not avaliable on ENCORE database.