HIPK1

General Information

Gene Name       : HIPK1
Gene ID             : ENSG00000163349.21
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HIPK1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HIPK1ENSG00000163349.2116.8211.9414.38ENCSR000AEF
HepG2HIPK1ENSG00000163349.2116.8018.9817.89ENCSR985KAT
K562HIPK1ENSG00000163349.2124.9024.1424.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HIPK1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HIPK1 RNA is bound by 30 proteins.  







eCLIP assay for HIPK1 is not avaliable on ENCORE database.





30 proteins are bound to HIPK1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1114517499114517587+3'-UTR3.8906817.77591K562PUM2
chr1114520059114520169+3'-UTR5.1624814.26643HepG2FUBP3
chr1114519432114519485+3'-UTR5.6117214.79039K562YBX3
chr1114517698114517761+3'-UTR3.863377.08696K562TARDBP
chr1114517566114517629+3'-UTR3.004915.58413K562TARDBP
chr1114519173114519219+3'-UTR3.301736.97264K562YBX3
chr1114517627114517724+3'-UTR3.696845.77184K562HNRNPM
chr1114516380114516442+3'-UTR3.887467.23979K562IGF2BP1
chr1114517602114517664+3'-UTR3.573825.35418HepG2FUBP3
chr1114519395114519432+3'-UTR6.0159917.71054K562YBX3
chr1114517715114517765+3'-UTR3.733487.71013HepG2PCBP2
chr1114518687114518716+3'-UTR3.513833.88742K562FAM120A
chr1114520247114520312+3'-UTR4.426323.50357HepG2QKI
chr1114517469114517602+3'-UTR5.5950118.57663HepG2FUBP3
chr1114516181114516227+3'-UTR3.053983.50044K562YBX3
chr1114518601114518706+3'-UTR3.789867.00366K562LIN28B
chr1114517428114517564+3'-UTR3.554498.11912K562KHSRP
chr1114520216114520317+3'-UTR4.130668.92068K562QKI
chr1114519387114519395+3'-UTR5.016857.83423K562YBX3
chr1114519874114519954+3'-UTR3.677058.05918HepG2FUBP3
chr1114518601114518670+3'-UTR4.1905413.98309K562PUM2
chr1114519021114519033+3'-UTR4.024298.28294K562YBX3
chr1114516813114516864+3'-UTR4.705345.08199HepG2FUBP3
chr1114517752114517785+3'-UTR3.084843.60337HepG2FUBP3
chr1114517629114517681+3'-UTR3.209303.80809K562TARDBP
chr1114519880114519931+3'-UTR4.251584.48529K562TIA1
chr1114519685114519752+3'-UTR3.926543.06406HepG2IGF2BP1
chr1114517392114517478+3'-UTR3.494157.84664K562PUM2
chr1114472438114472533+5'-UTR,intron-Distal4.078285.64813K562DDX24
chr1114472441114472544+5'-UTR,intron-Distal3.557029.68101HepG2GRSF1
chr1114472429114472524+5'-UTR,intron-Distal3.716294.74378HepG2GTF2F1
chr1114472363114472413+5'-UTR,intron-Distal3.509034.29728K562GEMIN5
chr1114495363114495425+5'-UTR,CDS,intron-Proximal3.870157.16374K562AQR
chr1114515672114515751+CDS3.835706.95607K562IGF2BP2
chr1114499758114499797+CDS4.220615.13745K562YBX3
chr1114508808114508886+CDS3.586494.53184K562IGF2BP1
chr1114508846114508895+CDS,intron-Proximal4.651036.99355K562LIN28B
chr1114506033114506141+CDS,intron-Distal3.310805.44638K562IGF2BP2
chr1114505041114505118+CDS,intron-Proximal3.337876.61270K562PRPF8
chr1114483651114483757+CDS3.094815.43812K562UCHL5
chr1114511093114511143+CDS3.641927.95579K562IGF2BP1
chr1114483216114483261+CDS3.907133.02541K562IGF2BP2
chr1114483861114483929+CDS3.584437.39702K562RBM15
chr1114483565114483646+CDS3.941835.38772K562RBM15
chr1114500637114500730+CDS,intron-Proximal3.978205.02403K562SF3B4
chr1114499248114499335+CDS,intron-Proximal3.092407.20615HepG2BCLAF1
chr1114511095114511152+CDS4.012616.34884HepG2IGF2BP1
chr1114511143114511252+CDS4.2574117.78232K562IGF2BP1
chr1114511269114511349+CDS,intron-Proximal4.682528.30573K562AQR
chr1114500737114500823+CDS3.900005.23915K562IGF2BP1
chr1114499243114499330+CDS,intron-Proximal3.066926.84704K562DDX24
chr1114512757114512809+CDS3.898017.40140K562YBX3
chr1114483553114483659+CDS3.969153.11149HepG2G3BP1
chr1114508889114508955+CDS,intron-Proximal4.153076.39176K562AQR
chr1114505043114505061+CDS,intron-Proximal3.290533.81856K562IGF2BP1
chr1114499247114499321+CDS,intron-Proximal3.091933.21510HepG2PPIG
chr1114484026114484066+CDS4.597005.40333K562RBM15
chr1114510569114510627+CDS,intron-Proximal4.942345.65342K562AQR
chr1114484048114484149+CDS,intron-Proximal4.049094.16174HepG2PRPF8
chr1114511172114511243+CDS3.167754.85736K562IGF2BP2
chr1114495502114495604+CDS,intron-Proximal3.319794.83230K562AQR
chr1114504997114505058+CDS4.286354.29122K562IGF2BP2
chr1114511094114511151+CDS4.0796211.18511K562IGF2BP2
chr1114504937114505006+CDS,intron-Proximal3.939336.49446K562IGF2BP1
chr1114506007114506105+CDS,intron-Distal,intron-Proximal3.045045.39469K562IGF2BP1
chr1114505057114505119+CDS,intron-Proximal4.577076.39176K562AQR
chr1114504965114505081+CDS,intron-Proximal4.081684.67436K562GRWD1
chr1114505945114506035+CDS,intron-Distal,intron-Proximal5.090315.17615K562AQR
chr1114483206114483245+CDS4.411015.17013K562RBM15
chr1114505956114506024+CDS,intron-Distal,intron-Proximal3.689356.46304K562SF3B4
chr1114484067114484129+CDS,intron-Proximal4.288117.94395K562PRPF8
chr1114508851114508957+CDS,intron-Proximal3.646105.43815HepG2PRPF8
chr1114499790114499855+CDS,intron-Proximal3.294593.50904K562LIN28B
chr1114501078114501148+intron-Distal4.057863.89294K562KHSRP
chr1114502239114502258+intron-Distal3.931123.53569K562LIN28B
chr1114488220114488267+intron-Distal3.955224.57394K562HNRNPM
chr1114505437114505514+intron-Distal3.944054.77518HepG2U2AF2
chr1114484125114484248+intron-Distal,intron-Proximal3.143943.51696K562KHSRP
chr1114501148114501226+intron-Distal3.101553.28806K562KHSRP
chr1114484134114484192+intron-Distal,intron-Proximal3.834664.58287K562PRPF8
chr1114486133114486191+intron-Distal4.580366.13339K562KHSRP
chr1114514702114514792+intron-Distal3.314674.05280K562CSTF2T
chr1114502412114502508+intron-Distal3.998323.45805K562KHSRP
chr1114486019114486123+intron-Distal3.009735.88259K562KHSRP
chr1114505284114505400+intron-Distal3.360356.18396K562KHSRP
chr1114499451114499499+intron-Proximal3.199873.26275K562BUD13
chr1114484130114484166+intron-Proximal5.662637.81430K562AQR
chr1114484086114484130+intron-Proximal5.0800418.60307K562AQR
chr1114499453114499521+intron-Proximal4.190863.64144K562EFTUD2
chr1114484081114484086+intron-Proximal4.3605910.81562K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HIPK1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HIPK1 is not available on ENCORE database.

  • 96 RBPs can affect the levels of HIPK1.  








The Knockdown/knockout RNA-Seq assay for HIPK1 is not available on ENCORE database.





96 RBPs can affect the gene expression of HIPK1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HIPK1ENSG00000163349.171664.825001232.807600.433304.334403.02080HepG2AATF
HIPK1ENSG00000163349.171203.417401913.76780-0.669307.245305.81770HepG2ABCF1
HIPK1ENSG00000163349.17668.081502044.59090-1.6137031.0914029.54930HepG2AKAP1
HIPK1ENSG00000163349.172066.529902395.54200-0.213102.351401.70920HepG2AUH
HIPK1ENSG00000163349.17897.859201463.59020-0.705006.646005.15930HepG2BCCIP
HIPK1ENSG00000163349.172415.530101607.285600.587606.750505.57590HepG2CIRBP
HIPK1ENSG00000163349.17768.599201609.86150-1.0666040.0443038.20410HepG2CKAP4
HIPK1ENSG00000163349.171020.671802044.30160-1.002109.262707.89190HepG2CNOT7
HIPK1ENSG00000163349.171005.776001359.55420-0.434804.048603.24210HepG2DDX21
HIPK1ENSG00000163349.171615.406301330.931100.279402.342801.50940HepG2DDX24
HIPK1ENSG00000163349.172615.046801958.659800.416903.521402.82490HepG2DDX3X
HIPK1ENSG00000163349.171010.911401439.01450-0.509403.823402.92980HepG2DDX55
HIPK1ENSG00000163349.17907.707201797.34320-0.9856016.8738014.69130HepG2DDX5
HIPK1ENSG00000163349.171046.895901682.30230-0.684306.538005.61990HepG2DDX6
HIPK1ENSG00000163349.171179.246901540.55090-0.385605.338704.45390HepG2DKC1
HIPK1ENSG00000163349.171269.359201566.58860-0.303501.916001.35470HepG2DNAJC2
HIPK1ENSG00000163349.171702.326901140.002000.578406.188204.87610HepG2EIF3D
HIPK1ENSG00000163349.17864.925601573.46620-0.8633015.5909013.70270HepG2EWSR1
HIPK1ENSG00000163349.171455.03310967.098700.589207.336906.09330HepG2FUBP3
HIPK1ENSG00000163349.171350.017001892.38610-0.487202.959201.80770HepG2GRSF1
HIPK1ENSG00000163349.171805.967201537.298400.232302.595301.64370HepG2HDGF
HIPK1ENSG00000163349.17865.504801595.80180-0.8827014.9181013.61240HepG2HNRNPA1
HIPK1ENSG00000163349.172139.006201615.544400.404803.536502.83500HepG2HNRNPLL
HIPK1ENSG00000163349.17798.897301763.26440-1.1422041.9215039.78730HepG2HNRNPU
HIPK1ENSG00000163349.171465.866302000.52990-0.448602.962901.68720HepG2HSPD1
HIPK1ENSG00000163349.172171.615601700.609100.352602.689202.02250HepG2IGF2BP2
HIPK1ENSG00000163349.171079.481801710.40680-0.664005.517004.05350HepG2KHSRP
HIPK1ENSG00000163349.17895.335501305.88720-0.544504.861002.72290HepG2CCAR2
HIPK1ENSG00000163349.171669.638702639.17920-0.660606.190204.93880HepG2LARP4
HIPK1ENSG00000163349.17950.735201445.04660-0.604006.713204.98340HepG2LARP7
HIPK1ENSG00000163349.17865.477501871.44910-1.1126031.4449029.12420HepG2NOL12
HIPK1ENSG00000163349.172039.589601653.830800.302401.986301.36620HepG2PABPC4
HIPK1ENSG00000163349.171864.098801584.186700.234602.505701.92130HepG2PCBP1
HIPK1ENSG00000163349.171281.153701572.69750-0.295803.137302.35700HepG2PPIL4
HIPK1ENSG00000163349.171924.226401456.399700.401806.186705.08180HepG2PRPF4
HIPK1ENSG00000163349.171459.015101110.079100.394202.916202.08730HepG2PRPF8
HIPK1ENSG00000163349.172509.896901611.936400.6387015.9130014.80790HepG2PTBP1
HIPK1ENSG00000163349.172348.814401895.001400.309603.272902.54360HepG2PUM2
HIPK1ENSG00000163349.172119.764501640.123400.370006.607805.72670HepG2PUS1
HIPK1ENSG00000163349.172444.823601745.836900.485707.629306.67020HepG2QKI
HIPK1ENSG00000163349.172557.067401550.824600.721404.719903.81290HepG2RAVER1
HIPK1ENSG00000163349.172220.515201584.432800.486806.232705.25780HepG2RBM25
HIPK1ENSG00000163349.171978.559101670.778300.243802.717402.10570HepG2RECQL
HIPK1ENSG00000163349.17693.477901109.22770-0.677608.512007.50410HepG2RPS19
HIPK1ENSG00000163349.171420.245902052.57100-0.531303.791902.85470HepG2RPS3A
HIPK1ENSG00000163349.171343.397301570.28710-0.225102.530401.90990HepG2SAFB2
HIPK1ENSG00000163349.173229.901602057.801600.650302.101101.51240HepG2SF3A3
HIPK1ENSG00000163349.172104.526801678.292700.326404.502003.77540HepG2SF3B4
HIPK1ENSG00000163349.171438.876301712.89030-0.251503.282902.52970HepG2SLBP
HIPK1ENSG00000163349.171480.292201831.25760-0.307005.150904.31810HepG2SMN1
HIPK1ENSG00000163349.171005.998901581.68450-0.652805.154703.82130HepG2SMNDC1
HIPK1ENSG00000163349.173213.922702596.414500.307705.727505.07940HepG2SRFBP1
HIPK1ENSG00000163349.172272.971901720.542600.401602.636701.66260HepG2SRSF3
HIPK1ENSG00000163349.172127.379201763.836600.270303.392902.71200HepG2SRSF5
HIPK1ENSG00000163349.171682.764501425.121400.239602.700802.15430HepG2SRSF9
HIPK1ENSG00000163349.171382.121702254.35340-0.7058020.0494018.94350HepG2SSB
HIPK1ENSG00000163349.17615.035401290.61270-1.0693011.389509.10020HepG2STAU1
HIPK1ENSG00000163349.171006.830101304.75420-0.374003.602202.53850HepG2SUPT6H
HIPK1ENSG00000163349.171129.138201574.47470-0.479607.157406.32860HepG2TAF15
HIPK1ENSG00000163349.171932.277201574.494500.295302.236601.57510HepG2TARDBP
HIPK1ENSG00000163349.172178.014001446.798500.590009.288407.77380HepG2TIA1
HIPK1ENSG00000163349.171131.256201713.48220-0.599009.512708.68290HepG2TIAL1
HIPK1ENSG00000163349.17936.294501557.31660-0.734005.848003.75530HepG2TRA2A
HIPK1ENSG00000163349.17765.224601728.64770-1.1757043.4784041.59300HepG2TRIM56
HIPK1ENSG00000163349.172224.007701745.256200.349603.597802.58990HepG2TUFM
HIPK1ENSG00000163349.172590.367401652.986900.648008.432107.33410HepG2U2AF1
HIPK1ENSG00000163349.17558.78980846.23010-0.598705.106404.06640HepG2UCHL5
HIPK1ENSG00000163349.171345.412001824.95400-0.439808.186407.09040HepG2UPF1
HIPK1ENSG00000163349.17824.636901311.74230-0.669704.397503.11370HepG2UPF2
HIPK1ENSG00000163349.171360.673301838.48080-0.434202.604201.54750HepG2XPO5
HIPK1ENSG00000163349.17668.600601410.15440-1.0766016.3445014.61180HepG2XRN2
HIPK1ENSG00000163349.172732.062102007.102000.4448012.0803011.13850HepG2ZNF622
HIPK1ENSG00000163349.171570.024202473.13140-0.655607.584305.09120K562AKAP1
HIPK1ENSG00000163349.175376.934203996.988900.427804.537903.82060K562AQR
HIPK1ENSG00000163349.173243.486502458.894600.399403.785602.76450K562BOP1
HIPK1ENSG00000163349.173745.177204446.48780-0.247602.516801.40350K562CCDC124
HIPK1ENSG00000163349.173293.626104235.21180-0.362806.278304.57560K562CPEB4
HIPK1ENSG00000163349.173396.281902614.374600.377403.647502.74820K562CPSF6
HIPK1ENSG00000163349.173592.504304166.16350-0.213702.391701.58560K562DKC1
HIPK1ENSG00000163349.173150.462902474.301300.348403.206002.21810K562EFTUD2
HIPK1ENSG00000163349.174308.882502649.419200.701508.352506.39750K562EIF3D
HIPK1ENSG00000163349.173342.028102618.412300.351903.660702.71980K562EIF4A3
HIPK1ENSG00000163349.176162.229005324.855900.210603.130802.13410K562EIF4G2
HIPK1ENSG00000163349.172445.605703523.95550-0.527006.899605.50800K562FIP1L1
HIPK1ENSG00000163349.172580.880304686.89600-0.8608013.6152011.91910K562GRSF1
HIPK1ENSG00000163349.172097.035602898.56160-0.467004.144702.98990K562HNRNPM
HIPK1ENSG00000163349.172638.841603510.10430-0.411606.791205.38950K562HNRNPU
HIPK1ENSG00000163349.172742.218804777.65440-0.8010014.8863013.11880K562HSPD1
HIPK1ENSG00000163349.171276.502402131.53680-0.739707.151905.57510K562KRR1
HIPK1ENSG00000163349.171866.000502365.66620-0.342303.180201.66740K562LARP7
HIPK1ENSG00000163349.171615.018202436.39670-0.593208.684607.06920K562METAP2
HIPK1ENSG00000163349.172613.614603213.77740-0.298205.085104.01260K562MTPAP
HIPK1ENSG00000163349.173377.308905824.15540-0.7862015.2774012.23950K562NOL12
HIPK1ENSG00000163349.171718.186402405.41020-0.485404.928102.79810K562NUSAP1
HIPK1ENSG00000163349.171783.191602385.22450-0.419704.108702.31350K562PHF6
HIPK1ENSG00000163349.172744.199204000.47000-0.543807.021405.60240K562PPIG
HIPK1ENSG00000163349.173011.936902407.775200.322902.766802.01810K562PRPF8
HIPK1ENSG00000163349.171314.477802190.52670-0.7368011.787409.65470K562PSIP1
HIPK1ENSG00000163349.175725.348903839.636100.576308.418107.51860K562PUS1
HIPK1ENSG00000163349.174649.816003741.018000.313604.416003.68500K562RBM15
HIPK1ENSG00000163349.171580.671802452.72930-0.633906.482605.22140K562RPS19
HIPK1ENSG00000163349.173006.248902321.924900.372504.098302.77110K562SAFB
HIPK1ENSG00000163349.174511.203303523.402600.356406.038704.87030K562SF3A3
HIPK1ENSG00000163349.174163.180902458.166700.760003.548202.09570K562SNRNP200
HIPK1ENSG00000163349.172640.399203199.77080-0.277202.668501.97260K562SRSF1
HIPK1ENSG00000163349.173155.965602613.735500.271902.868702.03300K562SYNCRIP
HIPK1ENSG00000163349.171983.174903238.42940-0.7075010.490408.96740K562TARDBP
HIPK1ENSG00000163349.172644.225703123.81700-0.240502.160901.44480K562TIA1
HIPK1ENSG00000163349.172222.082403065.26890-0.464105.810404.09150K562TRA2A
HIPK1ENSG00000163349.171727.425202238.23360-0.373703.516602.42530K562TRIM56
HIPK1ENSG00000163349.173079.460203671.07120-0.253503.804402.30510K562TROVE2
HIPK1ENSG00000163349.175241.297606549.87590-0.321503.077801.59330K562UBE2L3
HIPK1ENSG00000163349.171943.245602467.47660-0.344602.654801.65900K562UCHL5
HIPK1ENSG00000163349.172690.860903786.30950-0.4927013.5567012.11140K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HIPK1 is not available on ENCORE database.





11 RBPs can affect the splicing of HIPK1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHIPK1ENSG00000163349.17chr1+114499745114499908114499248114499433114500687114500913-0.122000.000000.00008excludedK562AKAP8L
SEHIPK1ENSG00000163349.17chr1+1145052561145053041145048891145050601145060081145061430.051000.010950.08731includedK562AQR
SEHIPK1ENSG00000163349.17chr1+114497272114497392114495387114495511114498184114498271-0.064000.000250.00529excludedK562PUS1
SEHIPK1ENSG00000163349.17chr1+114499745114499908114499248114499433114500687114500913-0.261000.000000.00000excludedK562PUS1
SEHIPK1ENSG00000163349.17chr1+114506008114506143114504938114505060114508751114508894-0.127000.004950.08066excludedK562U2AF1
SEHIPK1ENSG00000163349.17chr1+114499745114499908114499248114499433114500687114500913-0.115000.003450.06125excludedK562U2AF1
SEHIPK1ENSG00000163349.17chr1+114499745114499908114499248114499433114500687114500913-0.073000.000590.04510excludedK562HNRNPUL1
SEHIPK1ENSG00000163349.17chr1+114499745114499908114499248114499433114500687114500913-0.100000.000010.00086excludedK562UTP18
SEHIPK1ENSG00000163349.17chr1+114499745114499908114499248114499433114500687114500913-0.063000.000970.02671excludedK562RBM15
SEHIPK1ENSG00000163349.17chr1+114499745114499908114499248114499433114500687114500913-0.120000.000000.00022excludedK562AGGF1
A3SSHIPK1ENSG00000163349.17chr1+114514445114514576114514520114514576114512577114512819-0.249000.000060.01076shorterK562EFTUD2
A5SSHIPK1ENSG00000163349.17chr1+114499745114499976114499745114499908114500687114500913-0.065000.000390.03785shorterK562FXR1
A5SSHIPK1ENSG00000163349.17chr1+114499745114499908114499745114499806114500687114500913-0.111000.000040.00761shorterK562UTP18
A5SSHIPK1ENSG00000163349.17chr1+1144997451144999081144997451144998061145006871145009130.118000.001510.07350longerK562SRSF1
A5SSHIPK1ENSG00000163349.17chr1+114499745114499908114499745114499806114500687114500913-0.157000.000000.00011shorterK562AKAP8L

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HIPK1 is not avaliable on ENCORE database.