FAM35A

General Information

Gene Name       : FAM35A
Gene ID             :
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FAM35A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FAM35A is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAM35A RNA is bound by 17 proteins.  







eCLIP assay for FAM35A is not avaliable on ENCORE database.





17 proteins are bound to FAM35A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr108891110888911198+3'-UTR,CDS3.469145.76104HepG2BCLAF1
chr108885493788855012+5'-UTR,intron-Distal,intron-Proximal5.264964.38825K562DROSHA
chr108885494488855007+5'-UTR,intron-Distal,intron-Proximal4.818403.32488HepG2DDX3X
chr108885491988855009+5'-UTR,intron-Distal,intron-Proximal3.895095.51270K562GTF2F1
chr108885668988856748+5'-UTR,intron-Proximal4.674609.24431K562DDX3X
chr108885496488855007+5'-UTR,intron-Distal,intron-Proximal4.145155.63105K562DDX3X
chr108885499788855093+5'-UTR,intron-Distal,intron-Proximal3.711503.39008HepG2AQR
chr108885493188854999+5'-UTR,intron-Distal4.232964.13881HepG2PRPF4
chr108885493988855012+5'-UTR,intron-Distal,intron-Proximal3.977417.15658HepG2NCBP2
chr108885492788855005+5'-UTR,intron-Distal4.177184.14518HepG2GTF2F1
chr108885492688854999+5'-UTR,intron-Distal4.082587.41879HepG2FAM120A
chr108893023388930283+CDS,intron-Proximal3.872825.97823HepG2BCLAF1
chr108891788688917912+CDS4.952036.13315HepG2BCLAF1
chr108893023388930260+CDS,intron-Proximal3.986273.24150HepG2HLTF
chr108894684088946919+CDS,intron-Proximal3.344365.00751HepG2BCLAF1
chr108891141888911508+CDS3.247254.35275HepG2HLTF
chr108895022688950303+CDS,intron-Proximal3.388535.40232HepG2U2AF2
chr108886138488861507+intron-Distal4.659017.20371HepG2ILF3
chr108886349888863620+intron-Distal3.890073.31824HepG2TIAL1
chr108886347388863580+intron-Distal3.992839.06734HepG2U2AF2
chr108886073988860830+intron-Distal3.122484.33187HepG2QKI
chr108889732688897408+intron-Distal3.992434.15306K562SAFB2
chr108888984988889912+intron-Distal3.006184.32069HepG2SUGP2
chr108888811888888178+intron-Distal4.092697.32721HepG2MATR3
chr108888790788887970+intron-Distal3.174115.67580HepG2U2AF2
chr108889762488897676+intron-Distal3.986273.26547HepG2HLTF
chr108888842488888525+intron-Distal3.742796.02877HepG2SUGP2
chr108886338088863453+intron-Distal3.029615.01844HepG2U2AF2
chr108885504288855208+intron-Distal,intron-Proximal4.455014.74377HepG2FASTKD2
chr108889877188898840+intron-Distal3.397833.07152HepG2HLTF
chr108885676188856831+intron-Proximal3.783914.96262HepG2TIAL1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAM35A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAM35A is not available on ENCORE database.

  • 111 RBPs can affect the levels of FAM35A.  








The Knockdown/knockout RNA-Seq assay for FAM35A is not available on ENCORE database.





111 RBPs can affect the gene expression of FAM35A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAM35AENSG00000122376.71062.936401343.49890-0.337904.508103.76820HepG2ACO1
FAM35AENSG00000122376.71214.383902451.86120-1.013708.871907.97880HepG2AKAP1
FAM35AENSG00000122376.71502.495102028.79790-0.433302.650601.88180HepG2ASCC1
FAM35AENSG00000122376.71604.214902095.74520-0.385606.432105.45440HepG2AUH
FAM35AENSG00000122376.7705.48000934.54270-0.405702.091501.30580HepG2BCLAF1
FAM35AENSG00000122376.71197.885201505.86600-0.330102.569201.98970HepG2BOP1
FAM35AENSG00000122376.7710.070702269.70330-1.676506.834305.28520HepG2CCAR1
FAM35AENSG00000122376.7937.329501343.18330-0.5190010.102508.99410HepG2CKAP4
FAM35AENSG00000122376.7996.214601602.74150-0.686004.591803.60230HepG2CNOT7
FAM35AENSG00000122376.71227.394101690.39670-0.461807.409806.45330HepG2CELF1
FAM35AENSG00000122376.71065.104601242.53320-0.222302.285401.52250HepG2DDX19B
FAM35AENSG00000122376.7654.696101085.82480-0.729907.202106.15990HepG2DDX21
FAM35AENSG00000122376.71335.01190989.407900.432102.658501.39440HepG2DDX27
FAM35AENSG00000122376.7803.764701071.86290-0.415303.702602.14390HepG2DDX52
FAM35AENSG00000122376.72275.127901569.890500.535202.648801.69420HepG2DDX59
FAM35AENSG00000122376.7729.469401101.50350-0.594608.845507.64020HepG2DNAJC21
FAM35AENSG00000122376.7750.580101091.75970-0.540609.724408.59060HepG2DNAJC2
FAM35AENSG00000122376.7956.552101278.95040-0.419002.944701.99600HepG2EEF2
FAM35AENSG00000122376.7789.904801066.27810-0.432803.222702.02730HepG2EFTUD2
FAM35AENSG00000122376.71400.877301939.71940-0.469503.027302.40790HepG2EIF2S1
FAM35AENSG00000122376.7666.228201038.27200-0.640105.221204.00840HepG2EIF3D
FAM35AENSG00000122376.72664.978001793.186300.5715013.2741011.71380HepG2EIF4G1
FAM35AENSG00000122376.71541.788902406.16750-0.6421014.8991013.68230HepG2ETF1
FAM35AENSG00000122376.7853.633001312.81750-0.621008.131906.71370HepG2EWSR1
FAM35AENSG00000122376.7467.203301682.35060-1.8484018.3252016.65250HepG2FIP1L1
FAM35AENSG00000122376.7989.353101436.55210-0.538103.483502.22880HepG2FUS
FAM35AENSG00000122376.7979.378202162.38710-1.1427011.8581010.52740HepG2FXR1
FAM35AENSG00000122376.71022.022902006.27330-0.973108.904907.74700HepG2G3BP1
FAM35AENSG00000122376.7657.99080924.46180-0.490503.887202.81160HepG2GEMIN5
FAM35AENSG00000122376.7832.049001181.61710-0.506003.789002.59190HepG2GNB2L1
FAM35AENSG00000122376.7901.701801567.12280-0.797409.191908.06980HepG2GPKOW
FAM35AENSG00000122376.71063.066101282.64260-0.270902.839101.84930HepG2HDGF
FAM35AENSG00000122376.7815.716801354.80550-0.731905.952703.87410HepG2HNRNPA0
FAM35AENSG00000122376.7722.660101112.05600-0.621807.170206.20270HepG2HNRNPA1
FAM35AENSG00000122376.7694.779401236.95100-0.8322011.7023010.36440HepG2HNRNPC
FAM35AENSG00000122376.71435.870402030.73460-0.500103.782402.97580HepG2HNRNPK
FAM35AENSG00000122376.71237.318301655.88780-0.420408.427207.30970HepG2HNRNPL
FAM35AENSG00000122376.7872.090201161.11340-0.413002.337401.46200HepG2HNRNPM
FAM35AENSG00000122376.7871.719001228.77340-0.495307.937506.95100HepG2HNRNPU
FAM35AENSG00000122376.71266.873602039.45470-0.686905.297204.39030HepG2IGF2BP2
FAM35AENSG00000122376.71036.245701255.15240-0.276503.599302.77300HepG2ILF2
FAM35AENSG00000122376.71589.578702163.13910-0.444503.036602.34970HepG2MAGOH
FAM35AENSG00000122376.7665.110401086.68030-0.708304.249002.95820HepG2METAP2
FAM35AENSG00000122376.7938.668401362.16220-0.537203.082702.23090HepG2MSI2
FAM35AENSG00000122376.7624.74960970.57660-0.635602.865601.75080HepG2NONO
FAM35AENSG00000122376.71432.978401838.37380-0.359405.437404.63310HepG2PCBP1
FAM35AENSG00000122376.7794.069701429.67400-0.848307.007905.15600HepG2PRPF6
FAM35AENSG00000122376.7497.76210815.91180-0.713005.692604.57810HepG2PRPF8
FAM35AENSG00000122376.71147.426801870.57070-0.7051017.2513016.10900HepG2PTBP1
FAM35AENSG00000122376.71400.383601826.41190-0.383207.771206.88190HepG2PUM1
FAM35AENSG00000122376.71323.804101825.11130-0.463306.330105.33020HepG2PUM2
FAM35AENSG00000122376.7970.103601368.43740-0.496308.838207.84150HepG2PUS1
FAM35AENSG00000122376.7928.658801312.48870-0.499102.303801.65720HepG2RAVER1
FAM35AENSG00000122376.7995.936002075.59300-1.059403.414901.37860HepG2RBM17
FAM35AENSG00000122376.71406.184602011.11670-0.516208.971908.16130HepG2RBM22
FAM35AENSG00000122376.7819.258501133.41960-0.468302.874401.79220HepG2RCC2
FAM35AENSG00000122376.71269.088302081.80160-0.7140018.3283017.17390HepG2NELFE
FAM35AENSG00000122376.7686.750101010.24020-0.556805.865405.00980HepG2RPS19
FAM35AENSG00000122376.7951.380701287.29890-0.436303.408102.52100HepG2RPS2
FAM35AENSG00000122376.71219.96550807.135600.595905.521904.44620HepG2RRP9
FAM35AENSG00000122376.72367.918801480.279500.677709.727708.47730HepG2SF3B1
FAM35AENSG00000122376.71512.495701947.58330-0.364805.648504.85450HepG2SF3B4
FAM35AENSG00000122376.7911.634001945.29380-1.093503.440201.77820HepG2SFPQ
FAM35AENSG00000122376.71394.543001649.65210-0.242403.169902.42680HepG2SLBP
FAM35AENSG00000122376.71061.935601276.12150-0.265103.257902.56930HepG2SMN1
FAM35AENSG00000122376.71943.550802271.49280-0.224902.700202.20240HepG2SRFBP1
FAM35AENSG00000122376.71636.163202032.82360-0.313204.617604.04590HepG2SRSF1
FAM35AENSG00000122376.7859.266201592.79890-0.890409.546307.59240HepG2SRSF3
FAM35AENSG00000122376.71191.698001698.75210-0.511509.709008.63070HepG2SRSF5
FAM35AENSG00000122376.71385.780301653.78290-0.255103.184502.60120HepG2SRSF9
FAM35AENSG00000122376.72488.167101972.211800.335205.716905.03080HepG2SSB
FAM35AENSG00000122376.71494.501301932.00440-0.370406.722205.82750HepG2SUCLG1
FAM35AENSG00000122376.7996.214601856.43410-0.898003.104401.97700HepG2TBRG4
FAM35AENSG00000122376.71151.991401680.84040-0.545107.341705.80930HepG2TUFM
FAM35AENSG00000122376.71222.586701635.03280-0.419407.081806.04920HepG2UPF1
FAM35AENSG00000122376.7684.485401578.56250-1.2055041.1125039.20370HepG2UTP3
FAM35AENSG00000122376.71074.074501276.80560-0.249402.762702.09090HepG2ZC3H8
FAM35AENSG00000122376.71588.610001798.22540-0.178802.050701.56140HepG2ZNF622
FAM35AENSG00000122376.72044.367103043.40000-0.574007.556405.56080K562ABCF1
FAM35AENSG00000122376.7927.310602332.43280-1.3307029.3455027.63750K562AQR
FAM35AENSG00000122376.71054.288401343.01230-0.349204.519603.27540K562BCLAF1
FAM35AENSG00000122376.71184.183201650.72290-0.479204.087503.02540K562BOP1
FAM35AENSG00000122376.7334.95410574.83380-0.779207.311005.38160K562CCAR1
FAM35AENSG00000122376.71219.490701755.20140-0.525406.946705.69620K562CPSF6
FAM35AENSG00000122376.7796.425301018.87520-0.355403.383702.19610K562CSTF2
FAM35AENSG00000122376.72864.171002432.787400.235403.031902.35320K562DDX47
FAM35AENSG00000122376.7793.630301227.46310-0.629104.473002.81190K562EEF2
FAM35AENSG00000122376.7831.446101186.08910-0.512504.389403.22250K562EFTUD2
FAM35AENSG00000122376.7887.628601073.53240-0.274302.603601.43870K562EIF2S1
FAM35AENSG00000122376.71347.466801921.80090-0.512207.291606.20620K562EIF2S2
FAM35AENSG00000122376.71068.985502187.60300-1.0331020.9505018.38680K562FIP1L1
FAM35AENSG00000122376.71296.697801785.85770-0.461804.518803.42330K562FMR1
FAM35AENSG00000122376.71054.700101513.66770-0.521204.900103.64720K562FTO
FAM35AENSG00000122376.71470.640501061.888600.469706.857005.96480K562FXR1
FAM35AENSG00000122376.71586.091501144.258300.471003.138302.37650K562G3BP2
FAM35AENSG00000122376.71116.675801675.79280-0.585607.442406.13690K562GPKOW
FAM35AENSG00000122376.71849.310002561.19320-0.469805.024704.00740K562GRSF1
FAM35AENSG00000122376.7747.928201223.54050-0.710108.604007.60300K562HNRNPC
FAM35AENSG00000122376.7744.187001092.47410-0.553904.308202.84650K562HNRNPF
FAM35AENSG00000122376.71741.522902198.49260-0.336203.305702.13870K562HNRNPL
FAM35AENSG00000122376.7746.236701329.96970-0.833708.879106.64910K562IGF2BP2
FAM35AENSG00000122376.71026.491701430.89860-0.479203.063202.07530K562KRR1
FAM35AENSG00000122376.71021.042501635.75770-0.679909.953708.21650K562METAP2
FAM35AENSG00000122376.71478.179101883.17800-0.349303.394702.57620K562NSUN2
FAM35AENSG00000122376.7862.497501204.46340-0.481803.730601.97600K562NUSAP1
FAM35AENSG00000122376.71035.587401457.65820-0.493204.162803.14120K562PCBP3
FAM35AENSG00000122376.7864.573901194.44080-0.466304.104302.31200K562PHF6
FAM35AENSG00000122376.7856.973001118.07790-0.383703.408902.51300K562POLR2G
FAM35AENSG00000122376.71749.595502483.28570-0.505205.812104.54860K562PPIG
FAM35AENSG00000122376.7668.381101096.99080-0.714808.581806.80100K562PSIP1
FAM35AENSG00000122376.72603.929703292.41060-0.338503.167902.14220K562PUM2
FAM35AENSG00000122376.7996.929801303.11280-0.386402.365001.59310K562RBM22
FAM35AENSG00000122376.7602.470801000.66210-0.732009.447407.59540K562RCC2
FAM35AENSG00000122376.71236.67140996.220800.311802.381201.38090K562SAFB
FAM35AENSG00000122376.7690.268301333.29750-0.949805.069203.08660K562SFPQ
FAM35AENSG00000122376.7596.08860948.62160-0.670307.022705.17230K562SRFBP1
FAM35AENSG00000122376.71450.227101903.50360-0.392403.900702.80770K562SRPK2
FAM35AENSG00000122376.7852.076401331.81140-0.644303.991203.14810K562SRSF1
FAM35AENSG00000122376.7729.96270990.77390-0.440703.803902.54000K562SRSF4
FAM35AENSG00000122376.7803.775401257.60680-0.645805.255803.72320K562SRSF5
FAM35AENSG00000122376.7872.429901102.03270-0.337103.120401.74130K562SSB
FAM35AENSG00000122376.71799.928501121.455300.6825011.9976010.28740K562SYNCRIP
FAM35AENSG00000122376.71001.286001348.04430-0.429003.110102.35990K562TARDBP
FAM35AENSG00000122376.7911.051501300.29780-0.513204.473403.39510K562TIA1
FAM35AENSG00000122376.7818.633801055.14590-0.366202.305201.45680K562TIAL1
FAM35AENSG00000122376.7912.267701275.58990-0.483604.327302.90990K562TRA2A
FAM35AENSG00000122376.7840.584101120.73300-0.415003.406102.33640K562TRIM56
FAM35AENSG00000122376.71908.354302559.34100-0.423403.882702.15540K562TRIP6
FAM35AENSG00000122376.71591.075501916.31860-0.268303.328601.92750K562TROVE2
FAM35AENSG00000122376.7938.342801146.07340-0.288502.277301.54970K562U2AF2
FAM35AENSG00000122376.7820.493501182.89310-0.527804.302003.00590K562UCHL5
FAM35AENSG00000122376.71565.421901996.76020-0.351103.266102.48910K562UPF1
FAM35AENSG00000122376.71291.132901776.07030-0.460103.864402.43270K562UTP3
FAM35AENSG00000122376.71232.423401708.58640-0.471303.157602.22630K562WDR3
FAM35AENSG00000122376.72066.465502627.77920-0.346703.416402.44110K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAM35A is not available on ENCORE database.





4 RBPs can affect the splicing of FAM35A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFAM35AENSG00000122376.7chr10+889356458893585288930596889307318893983188940060-0.192000.007280.09848excludedK562SF3B4
SEFAM35AENSG00000122376.7chr10+888566908885674688854952888550058891110688911391-0.220000.003390.05340excludedK562U2AF2
SEFAM35AENSG00000122376.7chr10+889356458893585288930596889307318893983188940060-0.256000.000010.00068excludedK562HNRNPU
SEFAM35AENSG00000122376.7chr10+8893564588935852889305968893073188939831889400600.201000.001600.02820includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAM35A is not avaliable on ENCORE database.