VRK1

General Information

Gene Name       : VRK1
Gene ID             : ENSG00000100749.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: VRK1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878VRK1ENSG00000100749.760.8251.3156.06ENCSR000AEF
HepG2VRK1ENSG00000100749.715.9635.1625.56ENCSR985KAT
K562VRK1ENSG00000100749.766.0271.6368.82ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for VRK1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • VRK1 RNA is bound by 19 proteins.  







eCLIP assay for VRK1 is not avaliable on ENCORE database.





19 proteins are bound to VRK1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr149734760797347699+3'-UTR,intron-Distal4.2997615.66535HepG2SUB1
chr149734760997347693+3'-UTR,intron-Distal4.0275111.55560K562TIA1
chr149732149797321577+CDS,intron-Proximal5.589948.93732K562SF3B4
chr149734747297347541+CDS,intron-Distal,intron-Proximal3.442344.41130K562AQR
chr149731932897319428+CDS,intron-Proximal3.746025.47851K562SF3B4
chr149734245297342556+CDS,intron-Distal,intron-Proximal3.031114.63112K562AQR
chr149734237797342461+CDS,intron-Distal,intron-Proximal3.1883111.37435K562UCHL5
chr149730410497304152+CDS4.165303.45943HepG2BCLAF1
chr149729987097299909+CDS3.446865.23038K562ZNF622
chr149734237897342453+CDS,intron-Distal3.288236.50573K562ZNF800
chr149726389097263966+intron-Distal4.826863.70058HepG2XPO5
chr149733298597333076+intron-Distal3.238154.86332HepG2SUGP2
chr149730720797307255+intron-Distal4.233817.61465K562EXOSC5
chr149730683297306858+intron-Distal4.304824.48560K562EXOSC5
chr149731962097319678+intron-Distal4.724317.66316K562KHSRP
chr149730666597306725+intron-Distal3.795815.78672K562HNRNPM
chr149727824097278315+intron-Distal4.764106.38584HepG2QKI
chr149727313397273221+intron-Distal5.8096011.50340HepG2PCBP2
chr149731954297319620+intron-Distal,intron-Proximal3.564336.80241K562KHSRP
chr149728527597285429+intron-Distal4.453134.58794K562KHSRP
chr149733380597333869+intron-Distal3.967677.54016K562TARDBP
chr149730543697305481+intron-Distal3.341595.02082K562EXOSC5
chr149732842697328491+intron-Distal4.598864.97123HepG2PCBP2
chr149732753597327617+intron-Distal3.7694010.23826K562KHSRP
chr149732736597327474+intron-Distal3.299518.65519K562KHSRP
chr149730568997305736+intron-Distal4.706985.44433K562EXOSC5
chr149729226097292362+intron-Distal4.525555.25174K562KHSRP
chr149732116897321276+intron-Distal3.874369.94478K562KHSRP
chr149727017797270274+intron-Distal3.406164.30679K562KHSRP
chr149739547197395603+intron-Distal4.535703.60414HepG2DDX59
chr149727758097277682+intron-Distal4.302773.83958HepG2QKI
chr149733393497334008+intron-Distal3.289865.49076K562PTBP1
chr149731971297319759+intron-Distal3.067873.46531K562KHSRP
chr149730666597306717+intron-Distal4.611318.51158K562EXOSC5
chr149733261697332670+intron-Distal3.885023.39864HepG2SUGP2
chr149727869797278749+intron-Distal3.954965.32632HepG2QKI
chr149730737797307431+intron-Distal3.261093.72904K562EXOSC5
chr149736922297369305+intron-Distal3.095253.06005HepG2QKI
chr149729649897296634+intron-Distal4.479095.46313K562KHSRP
chr149732137397321474+intron-Distal,intron-Proximal4.0962113.11913K562KHSRP
chr149733211497332192+intron-Distal3.185104.16517K562KHSRP
chr149731931997319391+intron-Proximal4.169334.89018K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for VRK1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for VRK1 is not available on ENCORE database.

  • 127 RBPs can affect the levels of VRK1.  








The Knockdown/knockout RNA-Seq assay for VRK1 is not available on ENCORE database.





127 RBPs can affect the gene expression of VRK1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
VRK1ENSG00000100749.3261.76340363.59690-0.474103.323102.66660HepG2ACO1
VRK1ENSG00000100749.3242.00800350.58210-0.534702.315001.82410HepG2AKAP1
VRK1ENSG00000100749.3223.94790365.33780-0.706106.075704.97940HepG2AKAP8L
VRK1ENSG00000100749.385.91100290.07230-1.7555015.6224013.92460HepG2ASCC1
VRK1ENSG00000100749.3213.45520604.25770-1.5012029.3244027.51380HepG2AUH
VRK1ENSG00000100749.3281.49360418.27380-0.571302.119801.30210HepG2BCCIP
VRK1ENSG00000100749.3113.18080363.50690-1.6834011.481109.81260HepG2BCLAF1
VRK1ENSG00000100749.359.64710338.55140-2.5049031.1792029.54490HepG2BOP1
VRK1ENSG00000100749.3185.95890424.00440-1.1891013.1542011.68590HepG2CALR
VRK1ENSG00000100749.3124.72720275.59020-1.143707.700806.46120HepG2CIRBP
VRK1ENSG00000100749.398.88200363.55710-1.8784030.1952028.53320HepG2CKAP4
VRK1ENSG00000100749.3113.42120310.79650-1.4543012.6041011.25590HepG2CPSF6
VRK1ENSG00000100749.3315.86750595.01580-0.9136012.3529011.18410HepG2CELF1
VRK1ENSG00000100749.3486.82220639.76730-0.394203.727302.88820HepG2DAZAP1
VRK1ENSG00000100749.3249.10790336.29300-0.432902.952402.09260HepG2DDX19B
VRK1ENSG00000100749.3141.56390283.19580-1.000307.211706.16860HepG2DDX21
VRK1ENSG00000100749.3124.93490335.82050-1.4265012.3947011.16110HepG2DDX3X
VRK1ENSG00000100749.3218.30840411.21900-0.913504.609903.63870HepG2DDX55
VRK1ENSG00000100749.3140.90480352.93620-1.324708.043306.42420HepG2DDX59
VRK1ENSG00000100749.364.23980288.50180-2.1670019.4414017.99880HepG2DDX6
VRK1ENSG00000100749.3181.86200310.91930-0.773705.220803.89990HepG2DHX30
VRK1ENSG00000100749.3200.58630347.87380-0.794306.601305.63970HepG2DKC1
VRK1ENSG00000100749.3175.79800322.37010-0.874807.420306.31260HepG2DNAJC21
VRK1ENSG00000100749.3170.50390319.49610-0.906008.958007.86520HepG2DNAJC2
VRK1ENSG00000100749.3124.70040260.73580-1.064106.379104.71450HepG2AGO1
VRK1ENSG00000100749.336.61540277.31890-2.9210029.7996027.98940HepG2EIF2S1
VRK1ENSG00000100749.3104.04210268.61050-1.368309.276207.71780HepG2EIF3D
VRK1ENSG00000100749.3158.94500306.45790-0.947205.828704.90250HepG2EIF4A3
VRK1ENSG00000100749.3390.48650631.18760-0.692808.248506.94620HepG2EIF4G1
VRK1ENSG00000100749.3215.71530604.63410-1.4869019.5224017.51690HepG2EIF4G2
VRK1ENSG00000100749.3226.97170693.75870-1.6119035.3147033.60420HepG2ETF1
VRK1ENSG00000100749.3221.25370355.33390-0.683504.761903.67200HepG2EWSR1
VRK1ENSG00000100749.3139.82330311.35440-1.155004.425903.14760HepG2FTO
VRK1ENSG00000100749.3165.35480286.84590-0.794704.467103.62990HepG2G3BP1
VRK1ENSG00000100749.3157.97080239.16790-0.598402.605601.74050HepG2GEMIN5
VRK1ENSG00000100749.3240.83760376.19800-0.643403.577602.41180HepG2GNB2L1
VRK1ENSG00000100749.3131.30840352.27880-1.4238010.857309.64630HepG2GPKOW
VRK1ENSG00000100749.3127.54260325.45820-1.3515011.8556010.66760HepG2HNRNPA1
VRK1ENSG00000100749.3379.49710587.97450-0.631704.145303.03820HepG2HNRNPA2B1
VRK1ENSG00000100749.3117.83740362.00300-1.6192016.6516015.09130HepG2HNRNPC
VRK1ENSG00000100749.3171.13070414.75930-1.2772017.2494015.65630HepG2HNRNPF
VRK1ENSG00000100749.3197.24100290.50230-0.558602.580401.90440HepG2HNRNPK
VRK1ENSG00000100749.3421.14230582.77270-0.468604.515203.67080HepG2HNRNPL
VRK1ENSG00000100749.3108.00590336.18910-1.6382015.4091014.08810HepG2HNRNPLL
VRK1ENSG00000100749.3278.86280359.61030-0.366902.194001.64750HepG2HNRNPU
VRK1ENSG00000100749.3200.25170408.41850-1.0282010.654309.32260HepG2IGF2BP1
VRK1ENSG00000100749.373.73890291.56580-1.9833018.9187017.33220HepG2IGF2BP2
VRK1ENSG00000100749.3196.82610117.948600.738703.085701.81220HepG2KHDRBS1
VRK1ENSG00000100749.3184.40980293.27810-0.669402.872501.84890HepG2KHSRP
VRK1ENSG00000100749.3335.93350605.20870-0.849303.629502.67930HepG2LARP4
VRK1ENSG00000100749.3167.06780281.13690-0.750802.520701.51380HepG2METAP2
VRK1ENSG00000100749.3188.91580318.39590-0.753104.174703.40260HepG2NCBP2
VRK1ENSG00000100749.3196.62290377.44970-0.940904.031002.69400HepG2NONO
VRK1ENSG00000100749.3199.76490298.12010-0.577602.732501.98820HepG2NSUN2
VRK1ENSG00000100749.354.85400113.18270-1.045003.235702.27170HepG2PABPC1
VRK1ENSG00000100749.3103.67990283.53020-1.4514011.8489010.38210HepG2PABPC4
VRK1ENSG00000100749.3124.45900326.45900-1.3912010.508908.66580HepG2PCBP2
VRK1ENSG00000100749.3180.33690285.67180-0.663704.272603.33480HepG2PRPF4
VRK1ENSG00000100749.381.63970317.39040-1.9589012.2160010.69090HepG2PRPF8
VRK1ENSG00000100749.3158.91550605.58940-1.9301034.3167032.51010HepG2PUF60
VRK1ENSG00000100749.3418.82500642.86660-0.618208.111907.20690HepG2PUM1
VRK1ENSG00000100749.3462.49190642.39290-0.474003.807203.02490HepG2PUM2
VRK1ENSG00000100749.3224.47230370.35270-0.722406.728105.83950HepG2PUS1
VRK1ENSG00000100749.3210.93540283.54160-0.426801.886301.35530HepG2QKI
VRK1ENSG00000100749.3239.50880398.57540-0.734805.960604.76200HepG2RBM15
VRK1ENSG00000100749.3296.38550579.85600-0.9682012.4108011.47440HepG2RBM22
VRK1ENSG00000100749.3174.08900257.34210-0.563902.691602.02490HepG2RBM25
VRK1ENSG00000100749.3190.60740360.85420-0.920805.298403.82210HepG2RCC2
VRK1ENSG00000100749.374.00240446.81250-2.5940041.5396039.63320HepG2RPLP0
VRK1ENSG00000100749.3142.74560309.48560-1.116406.812105.37770HepG2RPS10
VRK1ENSG00000100749.393.94690261.35480-1.4761012.5998011.40240HepG2RPS19
VRK1ENSG00000100749.3243.52420409.84540-0.751005.074804.01130HepG2RPS2
VRK1ENSG00000100749.380.31230313.98130-1.9670012.4569010.98710HepG2RRP9
VRK1ENSG00000100749.3150.22660262.33410-0.804304.524103.33670HepG2SERBP1
VRK1ENSG00000100749.3187.44680368.90370-0.976806.141105.11350HepG2SF3A3
VRK1ENSG00000100749.3136.95100332.74170-1.2807011.166409.83640HepG2SF3B1
VRK1ENSG00000100749.3351.43600580.67960-0.724509.191608.03000HepG2SLBP
VRK1ENSG00000100749.3188.56390321.32430-0.769004.234803.03090HepG2SMNDC1
VRK1ENSG00000100749.3193.88630415.94730-1.101203.423001.92840HepG2SNRNP200
VRK1ENSG00000100749.3132.54980370.24030-1.4819010.634009.11090HepG2SNRNP70
VRK1ENSG00000100749.3212.96640654.92970-1.6207035.6468034.38110HepG2SRFBP1
VRK1ENSG00000100749.3683.18560284.519501.2636023.0650021.98740HepG2SRSF1
VRK1ENSG00000100749.3339.56960597.93940-0.8163010.708009.58420HepG2SRSF5
VRK1ENSG00000100749.3149.81900407.49080-1.4435020.3579018.78940HepG2SRSF7
VRK1ENSG00000100749.397.07630231.47950-1.2537010.351109.40250HepG2SRSF9
VRK1ENSG00000100749.3287.13680568.64040-0.9858014.8091013.81170HepG2SSB
VRK1ENSG00000100749.3179.02370258.85470-0.532002.428601.54350HepG2SUPT6H
VRK1ENSG00000100749.382.04770409.41100-2.3190016.7365015.31830HepG2SUPV3L1
VRK1ENSG00000100749.394.02930327.76840-1.8015018.4620016.88740HepG2TARDBP
VRK1ENSG00000100749.3115.92980274.44350-1.243307.405405.91410HepG2TFIP11
VRK1ENSG00000100749.367.41370349.46270-2.3740034.2235032.82480HepG2TIAL1
VRK1ENSG00000100749.3150.91260352.55000-1.2241015.1744014.00270HepG2TRIM56
VRK1ENSG00000100749.3417.17010591.64620-0.504103.755402.72210HepG2TUFM
VRK1ENSG00000100749.3104.61940484.43430-2.211209.842507.86270HepG2U2AF2
VRK1ENSG00000100749.3426.29660626.25540-0.554903.364502.44240HepG2UBE2L3
VRK1ENSG00000100749.3106.46250327.16120-1.6197020.7534019.18790HepG2UPF1
VRK1ENSG00000100749.3206.30710336.27570-0.704905.505004.07300HepG2UTP18
VRK1ENSG00000100749.3226.56460315.86120-0.479402.703602.11220HepG2UTP3
VRK1ENSG00000100749.353.32030359.81470-2.7545050.4317048.85020HepG2ZNF622
VRK1ENSG00000100749.31638.241503424.96930-1.0639023.7321022.20030K562AQR
VRK1ENSG00000100749.31544.675502003.95740-0.375506.074304.63180K562BCLAF1
VRK1ENSG00000100749.3491.31040753.61090-0.617205.848704.16700K562CCAR1
VRK1ENSG00000100749.31670.773902513.27150-0.589103.307801.70970K562CKAP4
VRK1ENSG00000100749.32490.111302927.53840-0.233502.534101.47730K562CPEB4
VRK1ENSG00000100749.31221.638401702.88750-0.479205.812404.68340K562CPSF6
VRK1ENSG00000100749.31172.483201580.09120-0.430404.671703.26620K562DDX3X
VRK1ENSG00000100749.32348.990803029.15360-0.366906.314605.38750K562DDX47
VRK1ENSG00000100749.3992.575001642.35110-0.726504.139503.00410K562EFTUD2
VRK1ENSG00000100749.31441.326501735.53370-0.268003.084001.79410K562EIF2S1
VRK1ENSG00000100749.31727.566202449.52080-0.503805.466604.50590K562EIF2S2
VRK1ENSG00000100749.3483.45930766.57740-0.665002.856701.83430K562EIF3A
VRK1ENSG00000100749.3538.901301758.89030-1.7066012.5057010.12420K562EIF3D
VRK1ENSG00000100749.31540.795901937.01500-0.330204.019203.06980K562EIF3G
VRK1ENSG00000100749.3931.677101650.78280-0.8252013.5322011.65330K562EIF4A3
VRK1ENSG00000100749.31227.274901486.59800-0.276602.513001.43040K562EIF4B
VRK1ENSG00000100749.33395.403004370.73400-0.364306.389004.98330K562EIF4G2
VRK1ENSG00000100749.31321.562501732.68660-0.390803.305702.36630K562FMR1
VRK1ENSG00000100749.31136.304601625.82250-0.516805.842504.69250K562GPKOW
VRK1ENSG00000100749.32368.922303264.54410-0.462703.419202.58110K562GRSF1
VRK1ENSG00000100749.3617.191201938.48770-1.6511051.6411049.20470K562HNRNPC
VRK1ENSG00000100749.31228.226101731.05120-0.495105.744804.01500K562HNRNPF
VRK1ENSG00000100749.33050.591102581.216500.240902.530101.67500K562HNRNPU
VRK1ENSG00000100749.31696.912602335.34860-0.460705.228903.49020K562IGF2BP3
VRK1ENSG00000100749.3840.127901388.29180-0.724606.258104.79150K562KRR1
VRK1ENSG00000100749.31403.891401877.11400-0.419104.337102.53970K562LARP7
VRK1ENSG00000100749.31428.294501966.02370-0.461003.956302.13840K562LIN28B
VRK1ENSG00000100749.31162.798801728.47190-0.571907.689005.09240K562LSM11
VRK1ENSG00000100749.31865.653102413.04500-0.371203.831302.83350K562MAGOH
VRK1ENSG00000100749.31279.228701586.99090-0.311002.599401.75470K562METAP2
VRK1ENSG00000100749.31536.304802104.27680-0.453908.737307.37510K562MTPAP
VRK1ENSG00000100749.32013.710902337.93590-0.215403.291502.48360K562NSUN2
VRK1ENSG00000100749.31398.056101908.59460-0.449103.443101.79030K562NUSAP1
VRK1ENSG00000100749.31274.344502147.02300-0.7526012.5532010.38120K562PCBP2
VRK1ENSG00000100749.31351.631301892.54990-0.485605.240003.19720K562PHF6
VRK1ENSG00000100749.3968.724701738.05150-0.8433013.2766010.99890K562PSIP1
VRK1ENSG00000100749.32399.050504768.77330-0.9912023.3567020.90540K562PUF60
VRK1ENSG00000100749.34336.257304969.87960-0.196802.274001.40210K562PUM2
VRK1ENSG00000100749.32007.243402656.83790-0.404503.779503.15870K562PUS1
VRK1ENSG00000100749.31824.355302248.05030-0.301302.452201.66430K562RBM22
VRK1ENSG00000100749.3518.436201585.71900-1.6129047.2427043.84260K562RCC2
VRK1ENSG00000100749.31006.940101628.24390-0.693303.341402.44250K562RPS19
VRK1ENSG00000100749.31032.461901318.76250-0.353102.402601.47700K562RPS3
VRK1ENSG00000100749.31286.324402182.61200-0.762803.091801.79700K562SF1
VRK1ENSG00000100749.31778.526002307.10160-0.375405.302204.19940K562SF3A3
VRK1ENSG00000100749.31172.496201546.27340-0.399202.787801.81060K562SF3B1
VRK1ENSG00000100749.31314.307902102.03400-0.6775012.5427010.64110K562SF3B4
VRK1ENSG00000100749.3803.718201503.22210-0.9033014.4412011.63660K562SRFBP1
VRK1ENSG00000100749.3903.694901273.18490-0.494505.217903.69250K562SRSF4
VRK1ENSG00000100749.31649.031102170.56170-0.396403.767802.50550K562SRSF5
VRK1ENSG00000100749.33441.642002625.497500.390403.858602.23320K562SSRP1
VRK1ENSG00000100749.31543.553002326.05040-0.591607.157005.96160K562TARDBP
VRK1ENSG00000100749.31657.946202243.73460-0.436505.523104.30190K562TIA1
VRK1ENSG00000100749.3867.163301671.71820-0.9470013.7498011.55670K562TIAL1
VRK1ENSG00000100749.31044.132601775.95340-0.7663011.731409.48640K562TRIM56
VRK1ENSG00000100749.31700.126402023.61190-0.251302.207301.49000K562U2AF2
VRK1ENSG00000100749.31763.393102478.97130-0.4914010.791109.48760K562UPF1
VRK1ENSG00000100749.31606.897402121.16390-0.400604.488003.36100K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for VRK1 is not available on ENCORE database.





6 RBPs can affect the splicing of VRK1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEVRK1ENSG00000100749.3chr14+973224669732258797321560973216939732286497322923-0.073000.000050.00176excludedK562SF3B4
SEVRK1ENSG00000100749.3chr14+973224669732258797321560973216939732286497322923-0.080000.000030.00208excludedK562PRPF8
SEVRK1ENSG00000100749.3chr14+973224669732258797321560973216939732286497322923-0.068000.000090.00267excludedK562U2AF2
SEVRK1ENSG00000100749.3chr14+973224669732258797321560973216939732286497322923-0.051000.000510.01619excludedK562AGGF1
SEVRK1ENSG00000100749.3chr14+973224669732258797321560973216939732286497322923-0.073000.005110.07047excludedK562HNRNPC
A3SSVRK1ENSG00000100749.3chr14+9734749297347728973475139734772897342366973424570.101000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for VRK1 is not avaliable on ENCORE database.