THAP4

General Information

Gene Name       : THAP4
Gene ID             : ENSG00000176946.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: THAP4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878THAP4ENSG00000176946.113.6421.7812.71ENCSR000AEF
HepG2THAP4ENSG00000176946.11115.8236.3076.06ENCSR985KAT
K562THAP4ENSG00000176946.1153.0729.6341.35ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for THAP4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • THAP4 RNA is bound by 17 proteins.  







eCLIP assay for THAP4 is not avaliable on ENCORE database.





17 proteins are bound to THAP4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2242523981242524108-3'-UTR,CDS,intron-Distal3.513068.07578K562YBX3
chr2242576385242576522-5'-UTR,CDS,intron-Distal4.5836641.30178HepG2DDX3X
chr2242576317242576363-CDS,intron-Distal4.332274.27476HepG2AQR
chr2242573147242573214-CDS,intron-Distal4.090213.98564K562LIN28B
chr2242545690242545764-CDS,intron-Distal,intron-Proximal3.285785.24055HepG2PRPF8
chr2242576353242576432-CDS,intron-Distal3.536355.59242K562DDX3X
chr2242542308242542389-CDS,intron-Distal,intron-Proximal4.054256.79646HepG2PRPF8
chr2242545852242545904-CDS,intron-Distal,intron-Proximal4.242863.79000HepG2U2AF2
chr2242573115242573211-CDS,intron-Distal4.626889.16903HepG2LIN28B
chr2242572761242572805-CDS,intron-Distal3.217413.34848HepG2PPIG
chr2242541289242541361-CDS,intron-Distal,intron-Proximal3.120223.22545HepG2PPIG
chr2242541270242541313-CDS,intron-Distal,intron-Proximal3.910295.93840HepG2PRPF8
chr2242545778242545878-CDS,intron-Distal4.004406.33071HepG2SRSF1
chr2242559046242559123-intron-Distal7.3733041.74783HepG2AGGF1
chr2242545943242546029-intron-Distal,intron-Proximal3.950388.55689HepG2U2AF2
chr2242526114242526181-intron-Distal3.524523.64762HepG2QKI
chr2242541570242541674-intron-Distal,intron-Proximal4.502546.06839HepG2PRPF4
chr2242560296242560365-intron-Distal4.576384.07596K562GTF2F1
chr2242559052242559138-intron-Distal4.791265.00643HepG2CDC40
chr2242559123242559164-intron-Distal5.2767313.58116HepG2AGGF1
chr2242559889242560013-intron-Distal5.891516.88699HepG2XPO5
chr2242559192242559238-intron-Distal4.719898.21618HepG2HNRNPL
chr2242558963242559000-intron-Distal3.894467.34576K562HNRNPL
chr2242559202242559254-intron-Distal4.217544.59145HepG2XPO5
chr2242560079242560143-intron-Distal4.1079116.06595HepG2HNRNPL
chr2242559673242559697-intron-Distal5.0535711.63577K562AGGF1
chr2242559196242559333-intron-Distal5.2758635.69228HepG2AGGF1
chr2242559970242560025-intron-Distal3.342413.62826K562HNRNPL
chr2242560343242560377-intron-Distal6.2624130.63769K562AGGF1
chr2242572271242572331-intron-Distal,intron-Proximal4.653074.65563K562AQR
chr2242560340242560360-intron-Distal4.532985.43961HepG2AGGF1
chr2242558902242558963-intron-Distal5.4416712.28795K562HNRNPL
chr2242559042242559161-intron-Distal5.4134210.93217K562HNRNPL
chr2242559052242559150-intron-Distal3.991224.32914K562YBX3
chr2242542326242542375-intron-Distal,intron-Proximal5.260145.69951K562AQR
chr2242560828242560873-intron-Distal3.666348.16843K562AGGF1
chr2242559900242560041-intron-Distal5.5491053.64268K562AGGF1
chr2242559034242559163-intron-Distal5.2554841.13053HepG2HNRNPL
chr2242559045242559145-intron-Distal4.249378.01571HepG2GTF2F1
chr2242558916242559000-intron-Distal5.6625616.68855HepG2AGGF1
chr2242559518242559597-intron-Distal5.1393614.12351HepG2AGGF1
chr2242560137242560172-intron-Distal6.1913113.29577HepG2AGGF1
chr2242560062242560137-intron-Distal4.7184221.06589HepG2AGGF1
chr2242531741242531803-intron-Distal3.632615.12003HepG2HNRNPM
chr2242559535242559598-intron-Distal6.8630322.50268K562AGGF1
chr2242558205242558244-intron-Distal5.5170911.04892K562AGGF1
chr2242558917242558999-intron-Distal7.6754042.82595K562AGGF1
chr2242559803242559842-intron-Distal4.208456.88493HepG2AGGF1
chr2242559432242559493-intron-Distal7.1118827.70262K562AGGF1
chr2242559918242560045-intron-Distal5.5695942.57643HepG2AGGF1
chr2242559029242559143-intron-Distal4.560064.05848HepG2QKI
chr2242572244242572308-intron-Distal,intron-Proximal4.330526.77750HepG2RBM22
chr2242559940242560051-intron-Distal3.8501718.39704HepG2HNRNPL
chr2242559083242559143-intron-Distal4.407365.48327HepG2XPO5
chr2242559333242559385-intron-Distal5.0903518.04552HepG2AGGF1
chr2242558919242558991-intron-Distal5.523026.88699HepG2XPO5
chr2242560077242560179-intron-Distal3.830586.92817K562HNRNPL
chr2242559410242559491-intron-Distal4.9692117.32939HepG2AGGF1
chr2242559389242559490-intron-Distal3.194087.63423HepG2HNRNPL
chr2242559213242559310-intron-Distal7.9742254.61562K562AGGF1
chr2242567664242567755-intron-Distal4.226934.79286HepG2PRPF4
chr2242559038242559158-intron-Distal7.6016998.66264K562AGGF1
chr2242560120242560181-intron-Distal5.5761226.68206K562AGGF1
chr2242566895242567002-intron-Distal4.159236.98528HepG2HNRNPM
chr2242560309242560381-intron-Distal3.479147.28538K562HNRNPL
chr2242559902242559921-intron-Distal4.717767.94930HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for THAP4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for THAP4 is not available on ENCORE database.

  • 120 RBPs can affect the levels of THAP4.  








The Knockdown/knockout RNA-Seq assay for THAP4 is not available on ENCORE database.





120 RBPs can affect the gene expression of THAP4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
THAP4ENSG00000176946.7461.96720643.64590-0.478502.828801.74710HepG2AATF
THAP4ENSG00000176946.7979.235801241.81200-0.342704.421403.68810HepG2ACO1
THAP4ENSG00000176946.7909.517401560.49260-0.778802.009901.33650HepG2ASCC1
THAP4ENSG00000176946.71435.320401786.74060-0.316004.036903.23700HepG2AUH
THAP4ENSG00000176946.7631.46730933.43110-0.563805.975404.90000HepG2CALR
THAP4ENSG00000176946.71036.031701241.39690-0.260902.963102.27970HepG2CKAP4
THAP4ENSG00000176946.7690.56490973.23490-0.495004.039803.22320HepG2CPSF6
THAP4ENSG00000176946.7852.65040572.574500.574406.184104.66280HepG2YBX3
THAP4ENSG00000176946.7356.26390659.31960-0.888004.743702.81450HepG2CSTF2T
THAP4ENSG00000176946.71256.58860941.682500.416105.258704.42480HepG2CELF1
THAP4ENSG00000176946.71248.518501012.532400.302103.772902.93010HepG2DAZAP1
THAP4ENSG00000176946.7390.39910694.81760-0.831708.828607.22090HepG2DDX24
THAP4ENSG00000176946.7591.763001105.18870-0.901205.915004.50580HepG2DDX59
THAP4ENSG00000176946.7909.438401188.04000-0.385504.618903.78320HepG2DKC1
THAP4ENSG00000176946.7831.60890562.191400.564704.151803.30550HepG2DNAJC21
THAP4ENSG00000176946.7886.33630557.276300.669405.776604.88520HepG2DNAJC2
THAP4ENSG00000176946.7373.80640653.77530-0.806505.453003.90500HepG2AGO1
THAP4ENSG00000176946.7586.23870851.12940-0.537903.251302.27810HepG2EIF3D
THAP4ENSG00000176946.7893.449501648.00950-0.883302.388901.79390HepG2EIF4A3
THAP4ENSG00000176946.7812.68000998.93180-0.297702.557701.74730HepG2EIF4G1
THAP4ENSG00000176946.71239.75550956.911600.373502.481001.70840HepG2EIF4G2
THAP4ENSG00000176946.71540.629602051.48290-0.413107.449506.54320HepG2ETF1
THAP4ENSG00000176946.7929.844501213.34330-0.383903.507902.56550HepG2EWSR1
THAP4ENSG00000176946.71186.960801743.54710-0.554804.546803.57720HepG2FIP1L1
THAP4ENSG00000176946.7439.46530590.15300-0.425302.580501.34980HepG2FKBP4
THAP4ENSG00000176946.7933.969301374.16930-0.557106.813205.61260HepG2FUBP3
THAP4ENSG00000176946.7792.830301543.07640-0.960702.624901.97600HepG2G3BP1
THAP4ENSG00000176946.71343.541101071.194900.326703.827502.99610HepG2HNRNPF
THAP4ENSG00000176946.71131.81020922.337300.295203.365902.62900HepG2HNRNPL
THAP4ENSG00000176946.7965.681601202.78800-0.316802.675101.73860HepG2HNRNPM
THAP4ENSG00000176946.7770.89780627.166500.297602.622302.03230HepG2HNRNPU
THAP4ENSG00000176946.7682.624701647.34010-1.271008.539506.45070HepG2HSPD1
THAP4ENSG00000176946.71358.649101054.820100.365103.615502.79640HepG2IGF2BP1
THAP4ENSG00000176946.7843.11530640.627100.396104.857003.90820HepG2ILF2
THAP4ENSG00000176946.71235.136801835.33970-0.571402.202801.46830HepG2LARP4
THAP4ENSG00000176946.71108.876201410.81980-0.347403.250502.37630HepG2MSI2
THAP4ENSG00000176946.71192.964901004.025400.248701.958601.31430HepG2NOL12
THAP4ENSG00000176946.7950.75010642.680900.564903.207101.64790HepG2NOLC1
THAP4ENSG00000176946.71236.656001618.06410-0.387805.583304.76820HepG2PCBP1
THAP4ENSG00000176946.7942.68290559.379600.752805.720604.69510HepG2PPIL4
THAP4ENSG00000176946.7425.62310546.72610-0.361202.139701.42510HepG2PRPF8
THAP4ENSG00000176946.71088.566801646.50710-0.5970011.8329010.85770HepG2PTBP1
THAP4ENSG00000176946.71453.188601017.420500.5142010.970109.95320HepG2PUM1
THAP4ENSG00000176946.7943.895201264.84480-0.422306.390405.52340HepG2PUS1
THAP4ENSG00000176946.71165.178301783.06650-0.6138010.257309.16180HepG2QKI
THAP4ENSG00000176946.7864.019101714.64640-0.9888026.0319024.76680HepG2RBM22
THAP4ENSG00000176946.7936.853801618.30090-0.7886013.2422011.83180HepG2RBM25
THAP4ENSG00000176946.71115.973901832.34920-0.7154016.5820015.47120HepG2NELFE
THAP4ENSG00000176946.71400.924501706.68420-0.284803.253302.59190HepG2RECQL
THAP4ENSG00000176946.71577.135001153.955600.450602.120001.51230HepG2RPLP0
THAP4ENSG00000176946.71041.88290558.509900.8994021.0876019.54560HepG2SAFB2
THAP4ENSG00000176946.71301.264301714.10750-0.397505.713204.91490HepG2SF3B4
THAP4ENSG00000176946.71483.80980918.991900.6911017.4848016.00440HepG2SLBP
THAP4ENSG00000176946.7786.57970651.300700.272202.424201.81660HepG2SMN1
THAP4ENSG00000176946.71024.49570637.377900.684602.503701.59600HepG2SMNDC1
THAP4ENSG00000176946.7731.523901159.41910-0.664404.313403.32920HepG2SNRNP70
THAP4ENSG00000176946.71634.417701936.60590-0.244803.288902.75740HepG2SRFBP1
THAP4ENSG00000176946.7789.512801789.20570-1.1803041.8928040.53110HepG2SRSF1
THAP4ENSG00000176946.71152.12110946.315000.283802.872402.23460HepG2SRSF5
THAP4ENSG00000176946.71019.015301455.65590-0.514509.211908.30930HepG2SRSF9
THAP4ENSG00000176946.71160.666401681.39020-0.5347010.758509.87600HepG2SSB
THAP4ENSG00000176946.71432.570801076.218500.412506.744005.84850HepG2SUCLG1
THAP4ENSG00000176946.7271.87900705.81260-1.3763012.5813011.31430HepG2SUPV3L1
THAP4ENSG00000176946.7628.837001608.34240-1.3548042.7901040.92700HepG2TAF15
THAP4ENSG00000176946.7806.786701026.32850-0.347202.402901.72050HepG2TARDBP
THAP4ENSG00000176946.71126.067201477.70470-0.392103.578702.63260HepG2TIA1
THAP4ENSG00000176946.71021.18780614.861100.7318014.0061012.87630HepG2TRIM56
THAP4ENSG00000176946.71281.39900936.351500.452503.627202.61260HepG2TUFM
THAP4ENSG00000176946.71533.56890991.115900.629705.968204.70960HepG2UBE2L3
THAP4ENSG00000176946.7635.15080416.888700.607304.189503.25430HepG2UCHL5
THAP4ENSG00000176946.7808.056301351.00270-0.7415017.2032015.75330HepG2UPF1
THAP4ENSG00000176946.71143.262101388.64020-0.280502.851001.78870HepG2UTP18
THAP4ENSG00000176946.7674.044401105.57350-0.7139014.8416013.48630HepG2ZC3H8
THAP4ENSG00000176946.71297.321501485.84410-0.195702.139301.64070HepG2ZNF622
THAP4ENSG00000176946.71404.93230878.059300.6780013.0622011.92720K562AGGF1
THAP4ENSG00000176946.71288.58350913.681400.495903.984003.19810K562AKAP8L
THAP4ENSG00000176946.7924.666001220.61900-0.400602.868002.27100K562AQR
THAP4ENSG00000176946.71280.22860958.711200.417103.070402.10720K562ATP5C1
THAP4ENSG00000176946.7380.56420546.90740-0.523203.302302.34770K562BOP1
THAP4ENSG00000176946.7440.81430581.48530-0.399602.781001.99650K562CPSF6
THAP4ENSG00000176946.7766.87400487.834900.652504.622801.94580K562DDX28
THAP4ENSG00000176946.7945.43300631.887600.581206.510104.83000K562DDX3X
THAP4ENSG00000176946.71835.188001229.775500.5774012.1021010.84470K562DDX47
THAP4ENSG00000176946.71508.01040983.055700.6172011.786509.72760K562DKC1
THAP4ENSG00000176946.7910.76520593.634400.617402.781401.77440K562EIF3A
THAP4ENSG00000176946.7449.74730219.086501.0375011.8034010.14070K562EIF3G
THAP4ENSG00000176946.7501.32930681.06500-0.442002.771101.64360K562FKBP4
THAP4ENSG00000176946.7411.01450591.71370-0.525703.801402.79410K562FMR1
THAP4ENSG00000176946.7365.25170501.55950-0.457502.467801.60580K562FTO
THAP4ENSG00000176946.7957.61970686.530000.480005.585304.76750K562FXR1
THAP4ENSG00000176946.744.32300169.38350-1.9342011.8341010.16480K562G3BP2
THAP4ENSG00000176946.7384.87030783.87370-1.0262014.5405013.25940K562HNRNPC
THAP4ENSG00000176946.7250.94280369.06210-0.556502.675001.46600K562HNRNPK
THAP4ENSG00000176946.7864.15220599.867800.526503.841602.73410K562HNRNPM
THAP4ENSG00000176946.7708.86080369.836100.938502.867101.81860K562IGF2BP2
THAP4ENSG00000176946.7585.18760376.069700.637805.786703.95330K562IGF2BP3
THAP4ENSG00000176946.7569.87390865.31960-0.602602.889001.43740K562ILF2
THAP4ENSG00000176946.71202.50490969.571100.310502.313801.56790K562KIF1C
THAP4ENSG00000176946.7323.25640474.09890-0.552502.790401.85270K562KRR1
THAP4ENSG00000176946.7580.47820759.52220-0.387902.790901.39610K562LARP7
THAP4ENSG00000176946.7732.53070388.426700.9151012.3951010.52650K562MAGOH
THAP4ENSG00000176946.71264.04360928.177500.445502.646801.60210K562MAK16
THAP4ENSG00000176946.7512.65620387.599700.403302.501601.62780K562MATR3
THAP4ENSG00000176946.71491.443801086.174800.457405.391904.03730K562MBNL1
THAP4ENSG00000176946.71149.068501603.57980-0.480805.225103.68110K562MSI2
THAP4ENSG00000176946.7796.477901089.46040-0.451906.158404.99220K562MTPAP
THAP4ENSG00000176946.7751.57620450.088300.739605.754903.74090K562NONO
THAP4ENSG00000176946.7985.338901210.54320-0.297003.869703.00420K562NSUN2
THAP4ENSG00000176946.71074.80670601.451000.837504.035502.78230K562PABPN1
THAP4ENSG00000176946.7517.60870379.807000.446503.184201.73570K562PCBP1
THAP4ENSG00000176946.7561.469301065.91580-0.924805.088403.95960K562PCBP3
THAP4ENSG00000176946.7488.94500817.53960-0.741604.216203.22430K562POLR2G
THAP4ENSG00000176946.71197.30110827.912700.532105.292104.09650K562PPIG
THAP4ENSG00000176946.7698.35100377.400000.8878012.0622010.72740K562PTBP1
THAP4ENSG00000176946.71440.549601710.67880-0.247902.625601.68940K562PUM2
THAP4ENSG00000176946.71193.19190905.971900.397203.290702.70630K562PUS1
THAP4ENSG00000176946.71422.51330882.856900.688108.024007.04490K562RBM15
THAP4ENSG00000176946.7507.37990352.736100.524403.344401.77760K562RBM34
THAP4ENSG00000176946.7773.10110452.179900.773706.170804.94370K562RPS19
THAP4ENSG00000176946.7599.78660408.932400.552502.714601.72080K562RPS3
THAP4ENSG00000176946.71005.70770728.617600.464902.960801.84230K562SAFB
THAP4ENSG00000176946.7916.271201194.41570-0.382503.610702.68650K562SF3A3
THAP4ENSG00000176946.7255.75510176.030000.538802.845701.97870K562SF3B4
THAP4ENSG00000176946.71039.290001223.69730-0.235602.435801.55160K562SRPK2
THAP4ENSG00000176946.7580.91010370.006600.650705.892504.86860K562SRSF1
THAP4ENSG00000176946.7560.08710394.664900.504903.169302.02560K562SRSF4
THAP4ENSG00000176946.7519.78510349.514700.572503.747402.48930K562SRSF5
THAP4ENSG00000176946.7687.85800956.81490-0.476103.835002.21270K562SSRP1
THAP4ENSG00000176946.71070.67020820.088400.384602.101201.38480K562SYNCRIP
THAP4ENSG00000176946.7600.14340374.408800.680604.717403.78600K562TARDBP
THAP4ENSG00000176946.7627.20700361.175900.796108.842807.26470K562TIA1
THAP4ENSG00000176946.7583.49860354.567800.718606.446204.61330K562TRA2A
THAP4ENSG00000176946.790.86190169.49150-0.899504.640503.60620K562U2AF2
THAP4ENSG00000176946.71008.842101283.56030-0.347504.450403.56150K562UPF1
THAP4ENSG00000176946.7807.417201098.30910-0.443904.434703.31610K562WDR3
THAP4ENSG00000176946.7963.734801375.11930-0.512805.590804.29230K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for THAP4 is not available on ENCORE database.





1 RBPs can affect the splicing of THAP4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A5SSTHAP4ENSG00000176946.7chr2-242576355242576864242576776242576864242572331242573494-0.303000.000010.00538shorterHepG2SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for THAP4 is not avaliable on ENCORE database.