SPRY1

General Information

Gene Name       : SPRY1
Gene ID             : ENSG00000164056.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SPRY1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPRY1ENSG00000164056.100.040.100.07ENCSR000AEF
HepG2SPRY1ENSG00000164056.1017.7523.9020.82ENCSR985KAT
K562SPRY1ENSG00000164056.100.260.370.32ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPRY1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPRY1 RNA is bound by 18 proteins.  







eCLIP assay for SPRY1 is not avaliable on ENCORE database.





18 proteins are bound to SPRY1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4124324715124324831+3'-UTR5.6824420.77776HepG2FUBP3
chr4124322671124322733+3'-UTR,5'-UTR,intron-Proximal4.091929.80234HepG2U2AF2
chr4124324746124324814+3'-UTR3.719904.70769HepG2ZC3H11A
chr4124323706124323750+3'-UTR4.769545.32461HepG2LIN28B
chr4124324288124324312+3'-UTR3.488513.40672HepG2FUBP3
chr4124317952124318059+5'-UTR3.645524.85956HepG2NCBP2
chr4124319663124319690+5'-UTR,intron-Distal,intron-Proximal3.978118.96944HepG2PRPF8
chr4124319659124319755+5'-UTR,intron-Distal,intron-Proximal3.724557.99874HepG2BUD13
chr4124319667124319714+5'-UTR,intron-Distal,intron-Proximal5.606498.88638HepG2AQR
chr4124318883124318918+5'-UTR,intron-Distal3.524763.68756HepG2RBM15
chr4124318782124318890+5'-UTR,intron-Distal3.9423518.78076HepG2DDX3X
chr4124319365124319449+5'-UTR,intron-Distal4.330103.84763HepG2SRSF9
chr4124319378124319437+5'-UTR,intron-Distal3.088163.80737HepG2NKRF
chr4124319390124319439+5'-UTR,intron-Distal3.995016.16249HepG2RBM15
chr4124323286124323338+CDS5.4708910.07747HepG2RBM15
chr4124323239124323278+CDS4.587534.34093HepG2RBM15
chr4124323074124323131+CDS4.116984.22136HepG2RBM15
chr4124323365124323389+CDS4.485464.61181HepG2RBM15
chr4124319876124319921+intron-Distal3.221593.72734HepG2CSTF2T
chr4124319873124319932+intron-Distal3.287807.24250HepG2RBM15
chr4124319178124319256+intron-Distal3.691489.88696HepG2RBM15
chr4124319072124319159+intron-Distal,intron-Proximal4.3464923.33219HepG2DDX3X
chr4124319672124319764+intron-Distal,intron-Proximal3.250613.39064HepG2RBM22
chr4124318654124318742+intron-Distal,intron-Proximal4.0242710.56393HepG2SF3B4
chr4124319875124319932+intron-Distal3.503536.78739HepG2XRN2
chr4124320024124320078+intron-Distal3.038093.77382HepG2HNRNPM
chr4124319690124319734+intron-Distal,intron-Proximal4.7524611.50355HepG2PRPF8
chr4124319071124319126+intron-Distal,intron-Proximal5.7093811.53317HepG2RBM15
chr4124320965124321031+intron-Distal,intron-Proximal3.119844.49282HepG2HNRNPM
chr4124319871124319936+intron-Distal4.177184.13073HepG2GTF2F1
chr4124319794124319849+intron-Distal4.067455.77834HepG2XRN2
chr4124319873124319936+intron-Distal3.186406.84207HepG2NKRF
chr4124319033124319071+intron-Distal,intron-Proximal4.692264.34093HepG2RBM15
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPRY1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPRY1 is not available on ENCORE database.

  • 124 RBPs can affect the levels of SPRY1.  








The Knockdown/knockout RNA-Seq assay for SPRY1 is not available on ENCORE database.





124 RBPs can affect the gene expression of SPRY1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPRY1ENSG00000164056.61013.38580739.091100.455303.989802.72440HepG2AATF
SPRY1ENSG00000164056.6473.768501480.82560-1.6441030.9378028.52790HepG2ABCF1
SPRY1ENSG00000164056.61722.957301161.646400.5686012.7196011.61730HepG2ACO1
SPRY1ENSG00000164056.6521.530501001.56490-0.9414012.5177010.61880HepG2ADAR
SPRY1ENSG00000164056.6555.986701167.11870-1.0698027.9506025.91120HepG2AKAP8L
SPRY1ENSG00000164056.6742.174601308.75830-0.818403.727901.79940HepG2APOBEC3C
SPRY1ENSG00000164056.61069.701601416.78090-0.405403.003902.18660HepG2ASCC1
SPRY1ENSG00000164056.6664.297401176.13140-0.8241013.4493011.96860HepG2CALR
SPRY1ENSG00000164056.6720.229201346.03850-0.9022012.2392010.73280HepG2CIRBP
SPRY1ENSG00000164056.6665.256101161.41150-0.8039019.6432018.22860HepG2CKAP4
SPRY1ENSG00000164056.61047.735301401.34420-0.419502.043001.39140HepG2CNOT7
SPRY1ENSG00000164056.6548.15910802.45110-0.549804.513403.65300HepG2CPSF6
SPRY1ENSG00000164056.6382.78140542.64520-0.503503.493602.29730HepG2CSTF2
SPRY1ENSG00000164056.61163.838101506.10340-0.371906.004304.97100HepG2DAZAP1
SPRY1ENSG00000164056.6406.301801074.36460-1.4029048.7907046.44640HepG2DDX19B
SPRY1ENSG00000164056.6253.59850814.71900-1.6838033.1724031.22350HepG2DDX21
SPRY1ENSG00000164056.6516.00710797.86430-0.628806.554905.15640HepG2DDX24
SPRY1ENSG00000164056.6488.93710808.24320-0.725105.421303.68460HepG2DDX27
SPRY1ENSG00000164056.61047.387801640.25220-0.647106.742405.80730HepG2DDX3X
SPRY1ENSG00000164056.6634.028301199.58700-0.9199013.0378011.04670HepG2DDX5
SPRY1ENSG00000164056.62137.645401408.997400.601305.627804.77380HepG2DDX6
SPRY1ENSG00000164056.6725.30140972.73340-0.423503.512302.41400HepG2DHX30
SPRY1ENSG00000164056.6267.859001111.38540-2.0528074.6454072.42360HepG2DKC1
SPRY1ENSG00000164056.6750.754901008.54950-0.425904.736603.83730HepG2DNAJC21
SPRY1ENSG00000164056.6610.66310999.59300-0.7110014.8170013.42930HepG2DNAJC2
SPRY1ENSG00000164056.6316.37850975.98410-1.6252029.4289027.06370HepG2EEF2
SPRY1ENSG00000164056.6470.52360813.65760-0.790208.255606.33820HepG2EFTUD2
SPRY1ENSG00000164056.61134.38280750.742300.595404.510703.08810HepG2AGO1
SPRY1ENSG00000164056.6926.900301354.51650-0.547304.874204.09890HepG2EIF2S1
SPRY1ENSG00000164056.6724.678501123.54390-0.632607.575505.75560HepG2EIF2S2
SPRY1ENSG00000164056.6412.22110769.77010-0.9010012.3599010.41870HepG2EIF3G
SPRY1ENSG00000164056.6450.156301496.90630-1.7335033.7035031.51680HepG2EIF4A3
SPRY1ENSG00000164056.6549.898101282.95050-1.2222022.1523019.58390HepG2ESF1
SPRY1ENSG00000164056.61609.617302016.01130-0.324804.352703.62850HepG2ETF1
SPRY1ENSG00000164056.6635.274701135.15170-0.8374012.9160011.16690HepG2EWSR1
SPRY1ENSG00000164056.6401.72850729.23310-0.860208.852806.00970HepG2EXOSC9
SPRY1ENSG00000164056.6499.43450708.08400-0.503604.573003.03660HepG2FAM120A
SPRY1ENSG00000164056.6699.512701106.70550-0.661804.020202.68150HepG2FUS
SPRY1ENSG00000164056.6984.359401510.29660-0.617606.278405.26320HepG2FXR1
SPRY1ENSG00000164056.6816.095201401.03160-0.779708.595107.45840HepG2G3BP1
SPRY1ENSG00000164056.6426.665101487.36150-1.8016041.7948038.82190HepG2G3BP2
SPRY1ENSG00000164056.6302.61250705.44520-1.2211016.0492014.07560HepG2GEMIN5
SPRY1ENSG00000164056.6597.45860837.96180-0.488003.089702.01110HepG2GNB2L1
SPRY1ENSG00000164056.6267.12420909.62330-1.7678029.4234027.59790HepG2GPKOW
SPRY1ENSG00000164056.61355.437701109.050400.289303.267102.20990HepG2HDGF
SPRY1ENSG00000164056.6239.761401018.21110-2.0864051.4908049.44760HepG2HNRNPA1
SPRY1ENSG00000164056.61074.874101384.14220-0.364804.535503.38840HepG2HNRNPA2B1
SPRY1ENSG00000164056.6408.727701132.55480-1.4704029.9403027.95270HepG2HNRNPC
SPRY1ENSG00000164056.6712.40410879.62640-0.304202.756602.04060HepG2HNRNPF
SPRY1ENSG00000164056.61178.927701371.95130-0.218802.445901.80800HepG2HNRNPL
SPRY1ENSG00000164056.6449.87670868.07190-0.9483011.1624010.00100HepG2HNRNPLL
SPRY1ENSG00000164056.6714.845901031.87880-0.529605.254003.98820HepG2HNRNPM
SPRY1ENSG00000164056.6639.127901125.06820-0.8158018.0316016.58680HepG2HNRNPU
SPRY1ENSG00000164056.6909.315001411.78920-0.634705.264803.59310HepG2HSPD1
SPRY1ENSG00000164056.6537.43710866.17890-0.688608.790207.57030HepG2IGF2BP1
SPRY1ENSG00000164056.6507.081001424.12160-1.4898029.2781027.36790HepG2IGF2BP2
SPRY1ENSG00000164056.6872.021001149.22280-0.398205.262704.27760HepG2ILF2
SPRY1ENSG00000164056.6994.069501366.24330-0.458802.563201.30510HepG2ILF3
SPRY1ENSG00000164056.61021.465801432.41620-0.487803.153402.07330HepG2KHSRP
SPRY1ENSG00000164056.61012.195601410.56290-0.478802.751301.50880HepG2KRR1
SPRY1ENSG00000164056.61090.867701690.64320-0.632105.247304.09170HepG2LARP4
SPRY1ENSG00000164056.6496.18980862.03660-0.796908.734306.68510HepG2LIN28B
SPRY1ENSG00000164056.6517.446901510.82370-1.5459030.7944028.79430HepG2MAGOH
SPRY1ENSG00000164056.6404.86390695.21840-0.780007.253704.77610HepG2MARK2
SPRY1ENSG00000164056.6635.238101519.28280-1.2580019.2860017.73880HepG2MATR3
SPRY1ENSG00000164056.6575.505901210.48300-1.0727019.2395017.35190HepG2MSI2
SPRY1ENSG00000164056.6856.001701555.07290-0.8613010.724509.51920HepG2NCBP2
SPRY1ENSG00000164056.6483.42290742.23110-0.618605.408003.41690HepG2NIP7
SPRY1ENSG00000164056.62062.867401493.448000.465906.809505.61980HepG2NOL12
SPRY1ENSG00000164056.6606.10390769.72450-0.344802.183201.51640HepG2NSUN2
SPRY1ENSG00000164056.6276.72670592.32580-1.097907.794905.22720HepG2PA2G4
SPRY1ENSG00000164056.6845.228901384.90550-0.712407.650106.46520HepG2PABPC4
SPRY1ENSG00000164056.61332.380601113.646000.258602.570301.75150HepG2PARN
SPRY1ENSG00000164056.6832.950301344.90630-0.6912014.3446013.13910HepG2PCBP1
SPRY1ENSG00000164056.6673.513701047.71780-0.637504.085802.83960HepG2PCBP2
SPRY1ENSG00000164056.6394.09100655.20840-0.733408.321106.28600HepG2PKM
SPRY1ENSG00000164056.6982.087301370.99770-0.481303.335801.40370HepG2PPIG
SPRY1ENSG00000164056.6879.647001238.16200-0.493207.417406.22440HepG2PRPF4
SPRY1ENSG00000164056.6532.616901101.46680-1.048308.105406.12810HepG2PRPF6
SPRY1ENSG00000164056.6336.08590666.28550-0.9873010.389408.95320HepG2PRPF8
SPRY1ENSG00000164056.61078.514601368.47260-0.343503.941203.31380HepG2PTBP1
SPRY1ENSG00000164056.6382.659101425.62100-1.8975055.6129053.34890HepG2PUF60
SPRY1ENSG00000164056.61130.729301513.35280-0.420507.825906.93420HepG2PUM1
SPRY1ENSG00000164056.6876.560501512.25160-0.7868014.4194012.96530HepG2PUM2
SPRY1ENSG00000164056.6601.795301183.21480-0.9754026.3410024.79950HepG2PUS1
SPRY1ENSG00000164056.61164.227301482.13190-0.348303.690602.98530HepG2QKI
SPRY1ENSG00000164056.61545.658701011.247200.612003.346202.57340HepG2RAVER1
SPRY1ENSG00000164056.61026.291501685.02070-0.7153014.1483013.16020HepG2RBM22
SPRY1ENSG00000164056.6560.319701522.99510-1.4426050.7484049.10910HepG2NELFE
SPRY1ENSG00000164056.6763.077001418.43300-0.8944022.3705020.90940HepG2RECQL
SPRY1ENSG00000164056.6567.68130947.60210-0.739208.929007.80950HepG2RPLP0
SPRY1ENSG00000164056.6717.84770993.03310-0.468202.408201.52660HepG2RPS10
SPRY1ENSG00000164056.6497.85070770.92790-0.630906.337005.44770HepG2RPS19
SPRY1ENSG00000164056.6636.05300912.87470-0.521304.015303.06020HepG2RPS2
SPRY1ENSG00000164056.6713.062701407.64160-0.9812010.362808.85280HepG2RPS3A
SPRY1ENSG00000164056.6611.956501001.93290-0.7113013.5933012.32620HepG2SAFB2
SPRY1ENSG00000164056.6919.992201336.93030-0.539203.013801.39340HepG2SBDS
SPRY1ENSG00000164056.6504.31980773.76840-0.617605.115703.84760HepG2SERBP1
SPRY1ENSG00000164056.6731.566501225.71850-0.744606.155005.12560HepG2SF3A3
SPRY1ENSG00000164056.6877.716101424.79220-0.6989014.4553013.26670HepG2SF3B4
SPRY1ENSG00000164056.61050.483201366.93420-0.379905.756504.80600HepG2SLBP
SPRY1ENSG00000164056.6643.231301168.43980-0.8612019.9208018.43830HepG2SMN1
SPRY1ENSG00000164056.6772.519701030.14900-0.415202.276201.41690HepG2SMNDC1
SPRY1ENSG00000164056.61497.167801903.18350-0.346205.331204.69830HepG2SRFBP1
SPRY1ENSG00000164056.6510.381201487.16010-1.5429059.0002057.45500HepG2SRSF1
SPRY1ENSG00000164056.61130.321801407.58490-0.316503.736603.03020HepG2SRSF5
SPRY1ENSG00000164056.6844.647901209.87140-0.518408.627507.74860HepG2SRSF9
SPRY1ENSG00000164056.6208.821801652.43950-2.98430176.32580174.02280HepG2SSB
SPRY1ENSG00000164056.6680.43220999.01930-0.554103.167401.85380HepG2STAU1
SPRY1ENSG00000164056.61162.185401600.81880-0.462008.820107.81500HepG2SUCLG1
SPRY1ENSG00000164056.6696.275901009.94190-0.536505.207303.93980HepG2SUPT6H
SPRY1ENSG00000164056.6324.78860859.94240-1.4047019.5367018.02360HepG2SUPV3L1
SPRY1ENSG00000164056.6663.241201381.35430-1.058506.410304.86130HepG2TBRG4
SPRY1ENSG00000164056.6334.275101093.27700-1.7096047.0790045.48220HepG2TIAL1
SPRY1ENSG00000164056.6872.294801102.98250-0.338503.928203.28020HepG2TRIM56
SPRY1ENSG00000164056.61003.875601392.76010-0.472405.218003.97850HepG2TUFM
SPRY1ENSG00000164056.61005.23440507.969000.9846012.6195011.02430HepG2UCHL5
SPRY1ENSG00000164056.6703.413501087.02730-0.6279011.183209.95100HepG2UPF1
SPRY1ENSG00000164056.6527.59400787.34580-0.577603.428002.30460HepG2UPF2
SPRY1ENSG00000164056.6859.334601117.29440-0.378703.599702.42090HepG2UTP18
SPRY1ENSG00000164056.6879.134301049.47850-0.255502.114001.57570HepG2UTP3
SPRY1ENSG00000164056.6345.68550846.52010-1.2921018.6254016.80300HepG2XRN2
SPRY1ENSG00000164056.6624.038201221.91850-0.9694027.1907025.48830HepG2ZC3H8
SPRY1ENSG00000164056.6800.880701195.51860-0.5780011.6839010.75170HepG2ZNF622
SPRY1ENSG00000164056.653.0664025.462101.059301.863901.40080K562PUS1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPRY1 is not available on ENCORE database.





1 RBPs can affect the splicing of SPRY1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPRY1ENSG00000164056.6chr4+124318765124319011124317949124318087124322691124322948-0.225000.001450.07536excludedHepG2AKAP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPRY1 is not avaliable on ENCORE database.