SLC6A4

General Information

Gene Name       : SLC6A4
Gene ID             : ENSG00000108576.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SLC6A4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SLC6A4ENSG00000108576.96.807.877.33ENCSR000AEF
HepG2SLC6A4ENSG00000108576.912.5510.9511.75ENCSR985KAT
K562SLC6A4ENSG00000108576.90.040.010.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SLC6A4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SLC6A4 RNA is bound by 1 proteins.  







eCLIP assay for SLC6A4 is not avaliable on ENCORE database.





1 proteins are bound to SLC6A4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr172852495928525023-3'-UTR,intron-Distal3.782663.09432HepG2ZC3H11A
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SLC6A4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SLC6A4 is not available on ENCORE database.

  • 131 RBPs can affect the levels of SLC6A4.  








The Knockdown/knockout RNA-Seq assay for SLC6A4 is not available on ENCORE database.





131 RBPs can affect the gene expression of SLC6A4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SLC6A4ENSG00000108576.5146.14400252.15690-0.786903.622101.66270HepG2AARS
SLC6A4ENSG00000108576.5168.47750308.22890-0.871405.985404.46950HepG2AATF
SLC6A4ENSG00000108576.5184.57970387.81150-1.071107.912106.43200HepG2ABCF1
SLC6A4ENSG00000108576.564.37600302.63640-2.2330032.3653030.83380HepG2ACO1
SLC6A4ENSG00000108576.561.008901364.53190-4.4832041.1734039.46470HepG2AKAP1
SLC6A4ENSG00000108576.5191.32250304.08370-0.668504.873903.88070HepG2AKAP8L
SLC6A4ENSG00000108576.51782.825301129.099900.658907.435706.17690HepG2ASCC1
SLC6A4ENSG00000108576.575.73840257.27040-1.7642013.9089011.71290HepG2BCCIP
SLC6A4ENSG00000108576.5211.08830354.19520-0.746705.554104.50930HepG2CALR
SLC6A4ENSG00000108576.5203.72740376.34150-0.885405.415904.03110HepG2CCAR1
SLC6A4ENSG00000108576.574.81170129.79630-0.794902.598901.93000HepG2CPSF6
SLC6A4ENSG00000108576.5338.33080235.937900.519903.286302.17580HepG2YBX3
SLC6A4ENSG00000108576.5183.41580279.90930-0.609804.308303.29570HepG2DDX19B
SLC6A4ENSG00000108576.5474.56250236.244101.006207.328805.56890HepG2DDX1
SLC6A4ENSG00000108576.5165.19080340.19670-1.042208.772807.63570HepG2DDX21
SLC6A4ENSG00000108576.5138.00570236.65230-0.778003.803502.32380HepG2DDX27
SLC6A4ENSG00000108576.5855.082601307.25640-0.612403.105302.44710HepG2DDX3X
SLC6A4ENSG00000108576.5493.22560293.124800.750606.434004.51680HepG2DDX47
SLC6A4ENSG00000108576.598.15860252.96560-1.365809.320707.99910HepG2DDX55
SLC6A4ENSG00000108576.5274.88770147.395900.899003.745702.61370HepG2DDX59
SLC6A4ENSG00000108576.5248.509201122.63530-2.1755018.2557016.85730HepG2DDX6
SLC6A4ENSG00000108576.5382.67190223.428400.776203.724102.59370HepG2DHX30
SLC6A4ENSG00000108576.5153.07930289.54890-0.919507.215906.21930HepG2DKC1
SLC6A4ENSG00000108576.5482.14810231.640801.0575010.620609.31660HepG2DNAJC21
SLC6A4ENSG00000108576.5213.66830371.47230-0.797905.035003.82540HepG2EEF2
SLC6A4ENSG00000108576.5266.372501079.53910-2.0189015.3181013.99200HepG2EIF2S1
SLC6A4ENSG00000108576.590.56090301.55810-1.7355014.6298012.73940HepG2EIF3D
SLC6A4ENSG00000108576.5134.69440321.19080-1.2537012.1690010.23280HepG2EIF3G
SLC6A4ENSG00000108576.5106.284101193.17360-3.4888029.0046026.96840HepG2EIF4A3
SLC6A4ENSG00000108576.5213.453101161.42420-2.4439019.6623017.94510HepG2EIF4B
SLC6A4ENSG00000108576.5714.76700452.983700.657908.190506.89030HepG2EIF4G1
SLC6A4ENSG00000108576.5469.25830572.75280-0.287502.121101.58020HepG2ETF1
SLC6A4ENSG00000108576.5143.22930295.75700-1.046108.567607.11550HepG2EWSR1
SLC6A4ENSG00000108576.5161.89770324.14020-1.001508.304806.52310HepG2FASTKD2
SLC6A4ENSG00000108576.5176.69840391.57560-1.148008.672407.39970HepG2FIP1L1
SLC6A4ENSG00000108576.5399.58260210.537400.924305.772204.00650HepG2FKBP4
SLC6A4ENSG00000108576.5248.96620429.56580-0.786905.265502.98440HepG2FMR1
SLC6A4ENSG00000108576.5447.25460130.035801.7821010.191308.27480HepG2FTO
SLC6A4ENSG00000108576.5556.69490752.49350-0.434803.224802.38100HepG2FUBP3
SLC6A4ENSG00000108576.5294.620901203.39010-2.0302016.5316014.98780HepG2FXR1
SLC6A4ENSG00000108576.5595.320501116.56910-0.907304.929904.05250HepG2G3BP1
SLC6A4ENSG00000108576.5447.102801185.05670-1.4063010.201308.48760HepG2G3BP2
SLC6A4ENSG00000108576.572.32790268.50020-1.8923017.3228015.28880HepG2GEMIN5
SLC6A4ENSG00000108576.5191.30870345.68430-0.853605.850604.35340HepG2GNB2L1
SLC6A4ENSG00000108576.5276.76430147.111800.911604.983704.14080HepG2GPKOW
SLC6A4ENSG00000108576.560.11010231.92030-1.947909.779307.69550HepG2GRSF1
SLC6A4ENSG00000108576.5117.20940233.86050-0.996605.665704.78430HepG2HNRNPA1
SLC6A4ENSG00000108576.5289.43820421.97680-0.543904.264903.14680HepG2HNRNPA2B1
SLC6A4ENSG00000108576.5105.40500260.14230-1.303409.180407.97550HepG2HNRNPC
SLC6A4ENSG00000108576.5422.67160217.034700.961503.953702.13480HepG2HNRNPD
SLC6A4ENSG00000108576.5386.45020168.936101.1937014.6543013.17460HepG2HNRNPF
SLC6A4ENSG00000108576.5162.532801130.04760-2.7976026.1677024.23950HepG2HNRNPK
SLC6A4ENSG00000108576.5252.56680418.25770-0.727707.451606.39380HepG2HNRNPL
SLC6A4ENSG00000108576.5346.68770140.393501.304106.358505.44880HepG2HNRNPLL
SLC6A4ENSG00000108576.5124.20260270.11240-1.120908.852407.31320HepG2HNRNPM
SLC6A4ENSG00000108576.5880.68520258.421201.7688053.6219051.23340HepG2HNRNPU
SLC6A4ENSG00000108576.5423.76930166.352801.3489012.2754010.85990HepG2IGF2BP1
SLC6A4ENSG00000108576.5508.879201135.05640-1.157406.624205.62060HepG2IGF2BP2
SLC6A4ENSG00000108576.5100.841901064.84560-3.4005029.6418026.85620HepG2IGF2BP3
SLC6A4ENSG00000108576.5394.47190244.246100.691503.253501.80540HepG2ILF3
SLC6A4ENSG00000108576.5399.53850276.666600.530104.443303.16340HepG2KIF1C
SLC6A4ENSG00000108576.5941.85200432.474501.1228011.534709.09680HepG2KRR1
SLC6A4ENSG00000108576.5126.39350397.58590-1.6533016.0535014.08840HepG2LARP4
SLC6A4ENSG00000108576.5208.54770338.64640-0.699404.292802.87250HepG2LARP7
SLC6A4ENSG00000108576.5219.38760355.60690-0.696804.333402.81500HepG2LIN28B
SLC6A4ENSG00000108576.5150.159101203.80810-3.0030026.7356024.84710HepG2MAGOH
SLC6A4ENSG00000108576.5227.986801210.62240-2.4087019.6760018.11560HepG2MATR3
SLC6A4ENSG00000108576.5131.13690315.61160-1.267107.465305.82730HepG2METAP2
SLC6A4ENSG00000108576.5439.73850316.823600.472902.581201.79840HepG2MSI2
SLC6A4ENSG00000108576.5429.59590266.060000.691105.235503.57910HepG2NAA15
SLC6A4ENSG00000108576.5449.970801239.20180-1.4615010.024508.86310HepG2NCBP2
SLC6A4ENSG00000108576.5235.77530455.29880-0.9494010.534609.07770HepG2NOL12
SLC6A4ENSG00000108576.5300.05310124.502001.268909.427908.10690HepG2NSUN2
SLC6A4ENSG00000108576.5380.83740228.957300.734003.330702.35150HepG2PABPC1
SLC6A4ENSG00000108576.5667.374501103.87680-0.726003.841203.00200HepG2PABPC4
SLC6A4ENSG00000108576.5143.29490255.77310-0.835905.693804.53840HepG2PARN
SLC6A4ENSG00000108576.5630.674701123.45510-0.8330017.6169016.29690HepG2PCBP1
SLC6A4ENSG00000108576.5187.45220398.35470-1.087507.694206.05170HepG2PCBP2
SLC6A4ENSG00000108576.5122.73420224.66340-0.872203.594001.86020HepG2PNPT1
SLC6A4ENSG00000108576.5510.21040331.457600.622206.149005.04620HepG2PRPF4
SLC6A4ENSG00000108576.5531.464001143.09830-1.1049021.3790020.13450HepG2PTBP1
SLC6A4ENSG00000108576.5632.18710434.621700.540503.993403.29240HepG2PUF60
SLC6A4ENSG00000108576.5303.43620461.36910-0.604506.039905.23300HepG2PUM1
SLC6A4ENSG00000108576.5362.84010461.03270-0.345501.918701.35390HepG2PUM2
SLC6A4ENSG00000108576.5780.40360308.259201.3400032.3895030.71310HepG2PUS1
SLC6A4ENSG00000108576.52735.575501238.130001.1436036.9371035.09440HepG2QKI
SLC6A4ENSG00000108576.579.97660384.41640-2.2650018.6272016.95670HepG2RAVER1
SLC6A4ENSG00000108576.581.84440478.71330-2.5482047.4298045.79170HepG2RBM22
SLC6A4ENSG00000108576.5861.371701123.63490-0.383502.225601.61550HepG2RBM25
SLC6A4ENSG00000108576.5190.13420408.34870-1.102809.375907.53450HepG2RBM27
SLC6A4ENSG00000108576.5197.39050331.59680-0.748403.276002.11850HepG2RCC2
SLC6A4ENSG00000108576.5162.146801272.20790-2.9720091.5966089.60470HepG2NELFE
SLC6A4ENSG00000108576.5352.257201184.79950-1.7499050.5547048.60290HepG2RECQL
SLC6A4ENSG00000108576.5243.04400377.62340-0.635703.014802.03010HepG2RPS10
SLC6A4ENSG00000108576.579.43600293.42520-1.8851020.4388019.00650HepG2RPS19
SLC6A4ENSG00000108576.5162.00170376.61260-1.2171010.799609.30370HepG2RPS2
SLC6A4ENSG00000108576.5195.60870384.43240-0.974807.703105.93330HepG2RPS5
SLC6A4ENSG00000108576.5401.50880230.126200.802908.366707.33690HepG2SAFB2
SLC6A4ENSG00000108576.5351.51650236.741800.570202.770901.46070HepG2SART3
SLC6A4ENSG00000108576.5412.78450238.945200.788604.171602.28510HepG2SBDS
SLC6A4ENSG00000108576.592.63950554.76260-2.5822038.9863036.44310HepG2SF3A3
SLC6A4ENSG00000108576.5240.211201190.21920-2.3089063.8378061.71830HepG2SF3B4
SLC6A4ENSG00000108576.5104.22360329.29310-1.659705.435003.29330HepG2SFPQ
SLC6A4ENSG00000108576.5730.82370416.732300.8103013.8032012.44360HepG2SLBP
SLC6A4ENSG00000108576.5101.58070268.35040-1.4015012.0361010.84170HepG2SMN1
SLC6A4ENSG00000108576.585.79970391.98650-2.1918025.3612022.40850HepG2SMNDC1
SLC6A4ENSG00000108576.5407.55930154.609601.3983010.063108.57730HepG2SNRNP70
SLC6A4ENSG00000108576.552.67860540.68540-3.3595084.3985082.62380HepG2SRFBP1
SLC6A4ENSG00000108576.5209.807201242.28780-2.5659076.4279074.72260HepG2SRSF1
SLC6A4ENSG00000108576.5187.51590429.12440-1.1944015.3525014.04630HepG2SRSF5
SLC6A4ENSG00000108576.5479.18910165.977601.5295025.7907024.08480HepG2SRSF7
SLC6A4ENSG00000108576.5353.689901010.62990-1.5147034.4766032.94830HepG2SRSF9
SLC6A4ENSG00000108576.5202.89580469.43660-1.2102017.7345016.67350HepG2SSB
SLC6A4ENSG00000108576.5227.79180431.26960-0.920907.396905.43630HepG2SSRP1
SLC6A4ENSG00000108576.5185.33130488.03370-1.3969022.9846021.47250HepG2SUCLG1
SLC6A4ENSG00000108576.5127.82640251.79940-0.978105.485304.58430HepG2SUPV3L1
SLC6A4ENSG00000108576.5446.87240136.899701.7066021.5059019.84600HepG2TARDBP
SLC6A4ENSG00000108576.5838.956001026.03570-0.290402.337701.56710HepG2TIA1
SLC6A4ENSG00000108576.5109.44710251.04540-1.197709.518308.68800HepG2TIAL1
SLC6A4ENSG00000108576.5362.08190253.353000.515103.796703.15840HepG2TRIM56
SLC6A4ENSG00000108576.5237.45820334.91510-0.496102.424301.83280HepG2U2AF1
SLC6A4ENSG00000108576.5161.34060353.02050-1.129603.144302.09150HepG2U2AF2
SLC6A4ENSG00000108576.5236.51620449.43690-0.926206.245704.95860HepG2UBE2L3
SLC6A4ENSG00000108576.518.18980148.72930-3.0315021.4685019.43250HepG2UCHL5
SLC6A4ENSG00000108576.51359.58500491.987401.4664044.4014042.32570HepG2UPF1
SLC6A4ENSG00000108576.579.37160230.50800-1.538108.797606.96840HepG2UPF2
SLC6A4ENSG00000108576.5126.92220474.99790-1.9040033.7608032.02710HepG2UTP3
SLC6A4ENSG00000108576.5331.66070225.166200.558602.461301.43560HepG2XPO5
SLC6A4ENSG00000108576.5193.19900378.02530-0.968405.682003.87430HepG2XRCC5
SLC6A4ENSG00000108576.566.62780422.76140-2.6656033.6206030.69780HepG2XRCC6
SLC6A4ENSG00000108576.5251.02700384.07380-0.613503.188201.78660HepG2ZRANB2
SLC6A4ENSG00000108576.520.310901.101904.204104.238303.51570K562HNRNPC
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SLC6A4 is not available on ENCORE database.





3 RBPs can affect the splicing of SLC6A4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESLC6A4ENSG00000108576.5chr17-285361602853626028534749285348502853753228537664-0.389000.000450.01335excludedHepG2SRSF1
SESLC6A4ENSG00000108576.5chr17-285272142852734728521336285255482853018928530357-0.086000.000040.00317excludedHepG2HNRNPU
SESLC6A4ENSG00000108576.5chr17-285272142852734728521336285255482853018928530357-0.107000.000140.03748excludedHepG2PRPF4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SLC6A4 is not avaliable on ENCORE database.