SEMA4B

General Information

Gene Name       : SEMA4B
Gene ID             : ENSG00000185033.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SEMA4B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SEMA4BENSG00000185033.142.345.523.93ENCSR000AEF
HepG2SEMA4BENSG00000185033.149.112.745.92ENCSR985KAT
K562SEMA4BENSG00000185033.1412.217.339.77ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SEMA4B is not avaliable on ENCORE database.



Proteins bound to RNA
  • SEMA4B RNA is bound by 20 proteins.  







eCLIP assay for SEMA4B is not avaliable on ENCORE database.





20 proteins are bound to SEMA4B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr159076905790769079+3'-UTR,CDS,intron-Proximal3.792563.79442K562AQR
chr159076462990764708+3'-UTR,CDS4.349044.98640K562YBX3
chr159076302490763097+3'-UTR,CDS,intron-Proximal3.302494.11795K562YBX3
chr159076110690761155+3'-UTR,intron-Proximal3.344383.94787K562AQR
chr159076701590767071+3'-UTR,CDS,intron-Proximal4.284413.83824K562BUD13
chr159076105890761080+3'-UTR,CDS,intron-Proximal3.973855.47926K562AQR
chr159077085190770875+3'-UTR,CDS,intron-Proximal3.056563.08662K562YBX3
chr159077196090772035+3'-UTR,intron-Distal4.391494.78313HepG2UPF1
chr159076701890767074+3'-UTR,CDS,intron-Proximal4.451967.08280K562SF3B4
chr159076310390763172+3'-UTR,CDS,intron-Proximal3.874884.98250K562AQR
chr159076862590768677+3'-UTR,CDS,intron-Proximal4.992115.69951K562AQR
chr159077269490772754+3'-UTR3.014674.34904K562UPF1
chr159076108090761106+3'-UTR,intron-Proximal4.314046.48405K562AQR
chr159077228390772374+3'-UTR,intron-Distal5.378667.21253K562UPF1
chr159076299690763060+3'-UTR,CDS,intron-Proximal6.2119215.90046K562AQR
chr159076814890768204+3'-UTR,CDS,intron-Proximal3.423114.50936K562SF3B4
chr159077237890772511+3'-UTR,CDS,intron-Distal,intron-Proximal5.183977.98718HepG2UPF1
chr159076721890767287+3'-UTR,CDS,intron-Proximal5.6973710.84943K562AQR
chr159077270390772810+3'-UTR4.952898.88051HepG2PCBP2
chr159076494090765000+3'-UTR,CDS,intron-Proximal4.133983.28461K562BUD13
chr159076112690761213+3'-UTR,intron-Distal,intron-Proximal3.107803.13218K562PRPF8
chr159077235490772468+3'-UTR,intron-Distal,intron-Proximal4.063446.75060K562RBM15
chr159076499390765015+3'-UTR,CDS,intron-Proximal3.707605.35619K562AQR
chr159077239490772506+3'-UTR,CDS,intron-Proximal4.824485.85041HepG2AKAP1
chr159077153890771617+3'-UTR,CDS,intron-Distal,intron-Proximal3.659764.68928K562RBM15
chr159074473290744797+3'-UTR,5'-UTR,intron-Distal5.508956.58500HepG2DDX3X
chr159077074090770803+3'-UTR,CDS,intron-Proximal4.951964.69961K562SF3B4
chr159077277090772806+3'-UTR3.722194.14074K562UPF1
chr159077199790772034+3'-UTR,intron-Distal3.090623.04831K562RBM15
chr159077239190772544+3'-UTR,CDS,intron-Proximal5.2537013.75064K562UPF1
chr159076484790764995+3'-UTR,CDS3.001533.14823K562SND1
chr159076062090760676+3'-UTR,CDS,intron-Proximal5.699469.62108K562SF3B4
chr159077128090771333+3'-UTR,CDS3.463793.77784K562RBM15
chr159076294890763146+3'-UTR,CDS,intron-Proximal3.090464.68044K562BUD13
chr159072831190728325+5'-UTR,intron-Distal,intron-Proximal3.303924.28285K562AQR
chr159072824090728303+5'-UTR,intron-Distal3.645153.86664K562DDX3X
chr159072829390728368+5'-UTR,intron-Distal,intron-Proximal4.378397.35008K562PRPF8
chr159072818090728240+5'-UTR,intron-Distal5.145154.54356K562DDX3X
chr159072815290728281+5'-UTR,intron-Distal4.282474.87288HepG2NCBP2
chr159074493590745032+CDS,intron-Distal,intron-Proximal3.950553.86479HepG2PRPF8
chr159074484090744905+CDS,intron-Distal5.174925.65234K562XRCC6
chr159075100390751058+intron-Distal4.643818.02514K562SLTM
chr159072832590728356+intron-Distal,intron-Proximal3.986075.26367K562AQR
chr159074944590749517+intron-Distal4.365916.47842K562SLTM
chr159075105890751106+intron-Distal4.172675.71515K562SLTM
chr159073617590736254+intron-Distal4.554685.18738K562TARDBP
chr159075030590750357+intron-Distal3.950875.71515K562SLTM
chr159075098990751050+intron-Distal4.076563.26547HepG2HLTF
chr159074973590749763+intron-Distal4.227143.75568K562SLTM
chr159074986190749918+intron-Distal4.289903.36882K562SLTM
chr159075339090753428+intron-Distal4.479164.53722K562SLTM
chr159075302790753126+intron-Distal4.257114.96047K562SLTM
chr159075346390753534+intron-Distal5.687839.34978K562SLTM
chr159075059890750686+intron-Distal4.957986.79841HepG2HLTF
chr159075012390750192+intron-Distal4.469024.95197K562SAFB2
chr159075165490751761+intron-Distal3.456684.74067K562ILF3
chr159074571390745850+intron-Distal4.354303.90241K562MATR3
chr159075584790755943+intron-Distal3.775063.37809K562HNRNPL
chr159076501590765043+intron-Proximal4.239115.47926K562AQR
chr159076907990769112+intron-Proximal5.038675.65342K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SEMA4B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SEMA4B is not available on ENCORE database.

  • 130 RBPs can affect the levels of SEMA4B.  








The Knockdown/knockout RNA-Seq assay for SEMA4B is not available on ENCORE database.





130 RBPs can affect the gene expression of SEMA4B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SEMA4BENSG00000185033.10315.74890599.06030-0.923903.083602.08740HepG2ABCF1
SEMA4BENSG00000185033.10171.05460277.90310-0.700102.897701.87800HepG2ADAR
SEMA4BENSG00000185033.102390.62530768.008301.6381030.9175029.38090HepG2AKAP1
SEMA4BENSG00000185033.101065.45220614.736100.7933015.6042013.99160HepG2AKAP8L
SEMA4BENSG00000185033.10951.12140635.369300.581902.095301.40770HepG2ASCC1
SEMA4BENSG00000185033.101327.22330615.391801.1087030.9166029.05980HepG2AUH
SEMA4BENSG00000185033.10661.15790272.855401.2768012.6397010.91100HepG2BCLAF1
SEMA4BENSG00000185033.10457.35460320.851700.511303.205302.56690HepG2BOP1
SEMA4BENSG00000185033.10740.27690448.564000.722704.049402.56980HepG2BUD13
SEMA4BENSG00000185033.10508.66730344.149000.563603.901903.00920HepG2CALR
SEMA4BENSG00000185033.10413.69850611.72300-0.564306.723105.76900HepG2CKAP4
SEMA4BENSG00000185033.10719.98230294.565301.2893018.3225016.73720HepG2CPSF6
SEMA4BENSG00000185033.10919.79290493.004400.8996011.414309.34860HepG2CPSF7
SEMA4BENSG00000185033.10423.85950284.981700.572604.449503.15900HepG2YBX3
SEMA4BENSG00000185033.10117.50380193.91340-0.722702.407301.40070HepG2CSTF2
SEMA4BENSG00000185033.10677.38750445.996500.602803.587302.87450HepG2CELF1
SEMA4BENSG00000185033.10624.65520479.522800.381403.705402.86800HepG2DAZAP1
SEMA4BENSG00000185033.10383.51970565.89390-0.561206.623105.41850HepG2DDX19B
SEMA4BENSG00000185033.10425.14410285.387700.574904.241202.82770HepG2DDX1
SEMA4BENSG00000185033.101370.12970735.494000.897404.023903.28090HepG2DDX3X
SEMA4BENSG00000185033.101142.34310308.862601.8869030.0034027.89990HepG2DDX55
SEMA4BENSG00000185033.10635.60370334.498600.926005.576804.20220HepG2DDX59
SEMA4BENSG00000185033.102821.10870632.275202.1575056.5077054.28030HepG2DDX6
SEMA4BENSG00000185033.10398.60680269.903900.562402.741001.75980HepG2DHX30
SEMA4BENSG00000185033.10299.83220585.40250-0.9653013.7396012.46760HepG2DKC1
SEMA4BENSG00000185033.10802.14020279.842501.5191035.9352033.73980HepG2DNAJC21
SEMA4BENSG00000185033.10512.94750277.354200.8870012.9270011.62790HepG2DNAJC2
SEMA4BENSG00000185033.10278.91030424.29160-0.605302.368001.51260HepG2EEF2
SEMA4BENSG00000185033.101927.07310607.354401.6657021.8716020.31230HepG2EIF2S1
SEMA4BENSG00000185033.10516.29630344.366600.584203.368402.37590HepG2EIF3D
SEMA4BENSG00000185033.10988.24250453.201201.1246017.6122015.69980HepG2EIF4G2
SEMA4BENSG00000185033.10307.00650518.72380-0.756703.831602.55980HepG2ESF1
SEMA4BENSG00000185033.101037.77490706.604300.554406.595905.73360HepG2ETF1
SEMA4BENSG00000185033.10542.42620343.904100.657302.804501.68230HepG2FUS
SEMA4BENSG00000185033.10960.88670628.275300.612902.320701.70910HepG2G3BP1
SEMA4BENSG00000185033.10963.23190340.499101.5001023.8087020.95190HepG2GNB2L1
SEMA4BENSG00000185033.10999.61670584.158300.7749015.1574013.18120HepG2HDGF
SEMA4BENSG00000185033.10588.65790314.249200.905403.252002.50620HepG2HNRNPC
SEMA4BENSG00000185033.10563.07900436.798600.366303.059702.35280HepG2HNRNPL
SEMA4BENSG00000185033.10446.99390318.673300.488102.620902.00520HepG2HNRNPLL
SEMA4BENSG00000185033.101013.59080638.500200.666602.819802.13920HepG2IGF2BP2
SEMA4BENSG00000185033.10526.30130318.874400.722809.602008.31980HepG2ILF2
SEMA4BENSG00000185033.10743.06680559.322300.409704.610303.30270HepG2KIF1C
SEMA4BENSG00000185033.101049.96730489.210501.1017017.4680015.64630HepG2MSI2
SEMA4BENSG00000185033.10617.20330410.864900.587003.790502.36720HepG2NAA15
SEMA4BENSG00000185033.10939.12370475.495600.9818018.1239016.28530HepG2NOL12
SEMA4BENSG00000185033.10287.91410174.248900.724403.033301.51390HepG2NOLC1
SEMA4BENSG00000185033.102847.20850747.643901.9290017.4071015.14580HepG2PABPC1
SEMA4BENSG00000185033.101346.54500620.801801.117009.945708.59480HepG2PABPC4
SEMA4BENSG00000185033.10459.06850278.433500.721307.197006.04750HepG2PPIL4
SEMA4BENSG00000185033.10597.10190481.857500.309302.593402.01490HepG2PUM1
SEMA4BENSG00000185033.10851.66290481.498900.8227011.7792010.44820HepG2PUM2
SEMA4BENSG00000185033.10474.26510623.24260-0.394103.615302.93080HepG2PUS1
SEMA4BENSG00000185033.10960.25390728.193200.399001.968501.42760HepG2QKI
SEMA4BENSG00000185033.101294.66830659.475400.9731019.9705018.03140HepG2RBM15
SEMA4BENSG00000185033.10958.96460660.922200.536904.328803.50040HepG2RBM25
SEMA4BENSG00000185033.10564.80720748.35080-0.406002.950402.39430HepG2NELFE
SEMA4BENSG00000185033.10459.81070697.06200-0.600206.651205.75470HepG2RECQL
SEMA4BENSG00000185033.10547.15410378.767100.530503.088601.94950HepG2RPS5
SEMA4BENSG00000185033.10752.46070278.006401.4364035.7315033.81150HepG2SAFB2
SEMA4BENSG00000185033.10671.38180465.558900.528103.194602.46830HepG2SF3A3
SEMA4BENSG00000185033.10632.62480435.252100.539406.333905.34110HepG2SLBP
SEMA4BENSG00000185033.10414.33310324.208100.353802.156001.57670HepG2SMN1
SEMA4BENSG00000185033.10633.28570321.068300.979907.102205.51630HepG2SMNDC1
SEMA4BENSG00000185033.10514.25430265.148500.955602.853001.51970HepG2SNRNP200
SEMA4BENSG00000185033.10642.60810350.971200.872505.724004.59100HepG2SNRNP70
SEMA4BENSG00000185033.102129.90500667.018601.6749066.3050064.69150HepG2SRFBP1
SEMA4BENSG00000185033.10289.99140730.72310-1.3333018.0265017.04080HepG2SRSF1
SEMA4BENSG00000185033.10875.60770448.184000.9661019.5516018.09170HepG2SRSF5
SEMA4BENSG00000185033.10448.73900333.230700.429302.850702.14480HepG2SRSF7
SEMA4BENSG00000185033.10354.24610579.09650-0.709108.932908.11320HepG2SSB
SEMA4BENSG00000185033.10603.66860293.421301.040703.138501.84950HepG2SUB1
SEMA4BENSG00000185033.10729.31330509.697800.516806.470605.58960HepG2SUCLG1
SEMA4BENSG00000185033.101037.35200408.153301.3456012.5606010.67810HepG2SUPT6H
SEMA4BENSG00000185033.10488.23830307.409200.667302.916202.22450HepG2SUPV3L1
SEMA4BENSG00000185033.10329.73950656.90340-0.994407.750006.88770HepG2TAF15
SEMA4BENSG00000185033.10294.20730903.04890-1.618006.303904.76820HepG2TBRG4
SEMA4BENSG00000185033.10995.08430603.497500.7214010.204108.61910HepG2TIA1
SEMA4BENSG00000185033.10785.92750306.043601.3606033.3024031.61290HepG2TRIM56
SEMA4BENSG00000185033.10582.29920443.469500.392802.612401.76470HepG2TUFM
SEMA4BENSG00000185033.10385.20490517.22530-0.425201.825401.30460HepG2U2AF1
SEMA4BENSG00000185033.10587.72930308.135300.931502.538101.59470HepG2U2AF2
SEMA4BENSG00000185033.101063.12090469.417001.1793015.1971013.21310HepG2UBE2L3
SEMA4BENSG00000185033.10116.61580181.55590-0.638702.132201.46610HepG2UCHL5
SEMA4BENSG00000185033.10972.73780412.880201.2362026.1097024.41280HepG2UPF1
SEMA4BENSG00000185033.10588.33820398.618700.561505.659904.85270HepG2UTP3
SEMA4BENSG00000185033.101860.16610454.088302.03430131.04010128.85030HepG2ZNF622
SEMA4BENSG00000185033.10939.32250616.629900.607108.905007.96200K562AGGF1
SEMA4BENSG00000185033.10935.99170677.600600.466004.182602.91960K562AKAP8
SEMA4BENSG00000185033.101136.00580641.635700.824008.811807.57420K562AKAP8L
SEMA4BENSG00000185033.10813.110801372.22920-0.755004.057002.50410K562APOBEC3C
SEMA4BENSG00000185033.10813.528301191.32630-0.550305.033704.28450K562AQR
SEMA4BENSG00000185033.10899.53990673.238400.418004.338503.16650K562ATP5C1
SEMA4BENSG00000185033.101048.49200568.161500.883809.074607.31210K562BCLAF1
SEMA4BENSG00000185033.10876.97960528.905300.729407.206805.77570K562BOP1
SEMA4BENSG00000185033.10750.27180505.431400.569803.070201.55700K562BUD13
SEMA4BENSG00000185033.10712.80730549.579600.375102.502601.51000K562CCAR1
SEMA4BENSG00000185033.101128.56300736.892600.614902.608101.47430K562CCDC124
SEMA4BENSG00000185033.101005.54610636.830600.658906.818504.86630K562CIRBP
SEMA4BENSG00000185033.102004.204301011.343500.9867021.0740018.31280K562CPEB4
SEMA4BENSG00000185033.10701.20090431.035300.701907.643205.75550K562CSTF2
SEMA4BENSG00000185033.101551.75120852.793500.8635015.9650013.37270K562DDX3X
SEMA4BENSG00000185033.10616.445601046.32720-0.7633010.100308.94560K562DDX47
SEMA4BENSG00000185033.101132.83040786.710800.525903.360202.57980K562EIF2S2
SEMA4BENSG00000185033.10199.76510559.00990-1.4846012.0924010.00520K562EIF3A
SEMA4BENSG00000185033.101084.94240802.314200.435304.963403.34950K562EIF4B
SEMA4BENSG00000185033.101069.52770777.681700.459605.120303.26120K562EWSR1
SEMA4BENSG00000185033.10728.88310572.226800.349002.054901.31410K562FMR1
SEMA4BENSG00000185033.10433.32680926.53190-1.0964022.9278021.30230K562FXR1
SEMA4BENSG00000185033.1075.76360289.43340-1.9337017.0588014.92230K562G3BP2
SEMA4BENSG00000185033.10676.51360536.893800.333401.992501.31510K562GPKOW
SEMA4BENSG00000185033.10930.622701254.41410-0.430702.510801.65910K562HNRNPU
SEMA4BENSG00000185033.10453.01390707.13490-0.642402.062401.37210K562HSPD1
SEMA4BENSG00000185033.101425.77200594.693901.261403.821502.54190K562IGF2BP2
SEMA4BENSG00000185033.101040.27220604.676400.7826010.167607.74580K562IGF2BP3
SEMA4BENSG00000185033.10392.58170574.20110-0.548603.614301.89550K562ILF3
SEMA4BENSG00000185033.10873.44210680.920800.359102.413001.65000K562KIF1C
SEMA4BENSG00000185033.10688.95280458.486900.587403.489502.42630K562KRR1
SEMA4BENSG00000185033.10914.36950651.820900.488204.271702.85370K562MAK16
SEMA4BENSG00000185033.101223.18430762.805300.681209.533407.64660K562MBNL1
SEMA4BENSG00000185033.10702.97370524.075700.423603.099602.16970K562METAP2
SEMA4BENSG00000185033.101273.326401657.63440-0.380503.737702.42630K562MSI2
SEMA4BENSG00000185033.10392.899801034.58520-1.3968022.2486019.99600K562PCBP3
SEMA4BENSG00000185033.101031.624801598.04400-0.631408.286306.05150K562PNPT1
SEMA4BENSG00000185033.10313.56080793.53310-1.3395025.5939023.37390K562POLR2G
SEMA4BENSG00000185033.10865.18790592.278900.546602.324001.57310K562PPIG
SEMA4BENSG00000185033.10873.10810575.397500.601505.535104.19200K562PSIP1
SEMA4BENSG00000185033.10942.696501696.79850-0.847908.290006.87500K562PUF60
SEMA4BENSG00000185033.102178.334001768.343500.300703.106902.09180K562PUM2
SEMA4BENSG00000185033.101040.38990636.295800.709307.394406.55330K562PUS1
SEMA4BENSG00000185033.101016.16210619.999900.7127010.883809.72990K562RBM15
SEMA4BENSG00000185033.10883.94310567.100400.640205.646003.46340K562RBM34
SEMA4BENSG00000185033.10919.73100525.291900.8080011.069509.06030K562RCC2
SEMA4BENSG00000185033.10348.16390707.14810-1.0222013.5257011.31650K562SAFB
SEMA4BENSG00000185033.10386.18700731.06860-0.9207010.910408.23400K562SDAD1
SEMA4BENSG00000185033.10807.29640444.262900.861603.818502.33960K562SF1
SEMA4BENSG00000185033.101633.171401019.596700.6796013.4752011.78590K562SF3A3
SEMA4BENSG00000185033.10403.72480300.736500.424802.570301.74920K562SF3B4
SEMA4BENSG00000185033.10154.43090260.82810-0.756104.502202.35610K562SND1
SEMA4BENSG00000185033.10786.65000497.930000.659706.298504.57930K562SRFBP1
SEMA4BENSG00000185033.10647.87840903.19840-0.479303.531501.79700K562SRSF9
SEMA4BENSG00000185033.101178.404101480.44860-0.329203.507901.81180K562SUCLG1
SEMA4BENSG00000185033.10280.33950795.97450-1.5055031.2412028.81750K562SYNCRIP
SEMA4BENSG00000185033.10138.98480284.09440-1.031404.738502.63840K562TAF15
SEMA4BENSG00000185033.10802.57450580.674900.466802.730401.91930K562TIA1
SEMA4BENSG00000185033.10798.08250588.266500.440002.386901.51790K562TRIM56
SEMA4BENSG00000185033.10728.816201105.46250-0.601004.838702.48400K562TUFM
SEMA4BENSG00000185033.10194.84970280.30390-0.524602.316701.32760K562U2AF1
SEMA4BENSG00000185033.101358.009901095.690300.309603.565402.75760K562UPF1
SEMA4BENSG00000185033.101378.28020774.551100.831309.933907.81430K562UTP3
SEMA4BENSG00000185033.10664.74220974.90720-0.552508.883307.45370K562WDR43
SEMA4BENSG00000185033.10632.08960846.26260-0.421003.740701.59190K562ZNF800
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SEMA4B is not available on ENCORE database.





4 RBPs can affect the splicing of SEMA4B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESEMA4BENSG00000185033.10chr15+9074468990744967907281949072831390760670907608340.372000.000410.09008includedK562PUM1
SESEMA4BENSG00000185033.10chr15+907446899074496790728194907283139076067090760834-0.473000.000090.00229excludedK562PUS1
SESEMA4BENSG00000185033.10chr15+9074468990744967907281949072831390760670907608340.430000.000140.03193includedK562EIF4G2
A3SSSEMA4BENSG00000185033.10chr15+9077076990770874907707889077087490768892907690590.073000.007340.04047longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SEMA4B is not avaliable on ENCORE database.